LOCUS       DAVHBD010000001       108052 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000001 DAVHBD010000000
VERSION     DAVHBD010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 108052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 108052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..108052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.001"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(151..228)
                     /locus_tag="VVK04_000001"
                     /pseudo
     CDS             complement(151..228)
                     /locus_tag="VVK04_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            299..913
                     /locus_tag="VVK04_000002"
     CDS             299..913
                     /locus_tag="VVK04_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU3988729.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAVLRLVF"
     gene            1017..1847
                     /locus_tag="VVK04_000003"
     CDS             1017..1847
                     /locus_tag="VVK04_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3988730.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKIFDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1888..1965
                     /locus_tag="VVK04_000004"
                     /pseudo
     CDS             1888..1965
                     /locus_tag="VVK04_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            2069..2899
                     /locus_tag="VVK04_000005"
     CDS             2069..2899
                     /locus_tag="VVK04_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3988731.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            3053..3907
                     /locus_tag="VVK04_000006"
     CDS             3053..3907
                     /locus_tag="VVK04_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU3988732.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNVTTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            4007..5380
                     /locus_tag="VVK04_000007"
     CDS             4007..5380
                     /locus_tag="VVK04_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU3988733.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            5373..6434
                     /locus_tag="VVK04_000008"
     CDS             5373..6434
                     /locus_tag="VVK04_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU3988734.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            6436..7128
                     /locus_tag="VVK04_000009"
     CDS             6436..7128
                     /locus_tag="VVK04_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3988735.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(7158..7727)
                     /locus_tag="VVK04_000010"
     CDS             complement(7158..7727)
                     /locus_tag="VVK04_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU3988736.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7862..8476
                     /locus_tag="VVK04_000011"
     CDS             7862..8476
                     /locus_tag="VVK04_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU3988737.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            8478..10124
                     /locus_tag="VVK04_000012"
     CDS             8478..10124
                     /locus_tag="VVK04_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU3988738.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            10136..11422
                     /locus_tag="VVK04_000013"
     CDS             10136..11422
                     /locus_tag="VVK04_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3988739.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGHPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            11474..12007
                     /locus_tag="VVK04_000014"
     CDS             11474..12007
                     /locus_tag="VVK04_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3988740.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            12085..12555
                     /gene="nrdI"
                     /locus_tag="VVK04_000015"
     CDS             12085..12555
                     /gene="nrdI"
                     /locus_tag="VVK04_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU3988741.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12848..14110)
                     /locus_tag="VVK04_000016"
     CDS             complement(12848..14110)
                     /locus_tag="VVK04_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU3988742.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(14420..14878)
                     /locus_tag="VVK04_000017"
     CDS             complement(14420..14878)
                     /locus_tag="VVK04_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU3988743.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14875..15315)
                     /locus_tag="VVK04_000018"
     CDS             complement(14875..15315)
                     /locus_tag="VVK04_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3988744.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            15671..17620
                     /gene="mutL"
                     /locus_tag="VVK04_000019"
     CDS             15671..17620
                     /gene="mutL"
                     /locus_tag="VVK04_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU3988745.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17945..18412)
                     /locus_tag="VVK04_000020"
     CDS             complement(17945..18412)
                     /locus_tag="VVK04_000020"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU3988746.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(18413..19618)
                     /locus_tag="VVK04_000021"
     CDS             complement(18413..19618)
                     /locus_tag="VVK04_000021"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU3988747.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(19638..20273)
                     /gene="ribE"
                     /locus_tag="VVK04_000022"
     CDS             complement(19638..20273)
                     /gene="ribE"
                     /locus_tag="VVK04_000022"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU3988748.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(20258..21358)
                     /gene="ribD"
                     /locus_tag="VVK04_000023"
     CDS             complement(20258..21358)
                     /gene="ribD"
                     /locus_tag="VVK04_000023"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU3988749.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVQQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(21492..21606)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            21763..22356
                     /gene="ruvA"
                     /locus_tag="VVK04_000024"
     CDS             21763..22356
                     /gene="ruvA"
                     /locus_tag="VVK04_000024"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU3988750.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            22366..22929
                     /locus_tag="VVK04_000025"
     CDS             22366..22929
                     /locus_tag="VVK04_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU3988751.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQA
                     GLSWETVLNKRQAFREVFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22926..23603
                     /locus_tag="VVK04_000026"
     CDS             22926..23603
                     /locus_tag="VVK04_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3988752.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(23758..24789)
                     /locus_tag="VVK04_000027"
     CDS             complement(23758..24789)
                     /locus_tag="VVK04_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU3988753.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCPKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(25044..25727)
                     /locus_tag="VVK04_000028"
     CDS             complement(25044..25727)
                     /locus_tag="VVK04_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU3988754.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(25739..26683)
                     /locus_tag="VVK04_000029"
     CDS             complement(25739..26683)
                     /locus_tag="VVK04_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU3988755.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            26815..29646
                     /gene="uvrA"
                     /locus_tag="VVK04_000030"
     CDS             26815..29646
                     /gene="uvrA"
                     /locus_tag="VVK04_000030"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU3988756.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            29639..30700
                     /locus_tag="VVK04_000031"
     CDS             29639..30700
                     /locus_tag="VVK04_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU3988757.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            30832..31230
                     /gene="spx"
                     /locus_tag="VVK04_000032"
     CDS             30832..31230
                     /gene="spx"
                     /locus_tag="VVK04_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU3988758.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            31296..31865
                     /locus_tag="VVK04_000033"
     CDS             31296..31865
                     /locus_tag="VVK04_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU3988759.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            31952..32218
                     /locus_tag="VVK04_000034"
     CDS             31952..32218
                     /locus_tag="VVK04_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU3988760.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            32222..32641
                     /gene="ruvX"
                     /locus_tag="VVK04_000035"
     CDS             32222..32641
                     /gene="ruvX"
                     /locus_tag="VVK04_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU3988761.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            32657..32962
                     /locus_tag="VVK04_000036"
     CDS             32657..32962
                     /locus_tag="VVK04_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU3988762.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            33220..34470
                     /locus_tag="VVK04_000037"
     CDS             33220..34470
                     /locus_tag="VVK04_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU3988763.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLHPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            34467..35009
                     /locus_tag="VVK04_000038"
     CDS             34467..35009
                     /locus_tag="VVK04_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU3988764.1"
                     /translation="MTPLFELVILGKLLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQSTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            35155..36687
                     /gene="cls"
                     /locus_tag="VVK04_000039"
     CDS             35155..36687
                     /gene="cls"
                     /locus_tag="VVK04_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU3988765.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLFELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36765..36908
                     /locus_tag="VVK04_000040"
     CDS             36765..36908
                     /locus_tag="VVK04_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988766.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            36945..38483
                     /locus_tag="VVK04_000041"
     CDS             36945..38483
                     /locus_tag="VVK04_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU3988767.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSVRRSRRETPVSLWSRFFKGNLYLLVFGLVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            38603..40810
                     /gene="nrdD"
                     /locus_tag="VVK04_000042"
     CDS             38603..40810
                     /gene="nrdD"
                     /locus_tag="VVK04_000042"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU3988768.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40822..40962
                     /locus_tag="VVK04_000043"
     CDS             40822..40962
                     /locus_tag="VVK04_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988769.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            41006..41512
                     /locus_tag="VVK04_000044"
     CDS             41006..41512
                     /locus_tag="VVK04_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3988770.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            41505..42095
                     /gene="nrdG"
                     /locus_tag="VVK04_000045"
     CDS             41505..42095
                     /gene="nrdG"
                     /locus_tag="VVK04_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU3988771.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            42092..42709
                     /locus_tag="VVK04_000046"
     CDS             42092..42709
                     /locus_tag="VVK04_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU3988772.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42975..43283
                     /gene="rpsJ"
                     /locus_tag="VVK04_000047"
     CDS             42975..43283
                     /gene="rpsJ"
                     /locus_tag="VVK04_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU3988773.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            43499..44125
                     /gene="rplC"
                     /locus_tag="VVK04_000048"
     CDS             43499..44125
                     /gene="rplC"
                     /locus_tag="VVK04_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU3988774.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            44150..44773
                     /gene="rplD"
                     /locus_tag="VVK04_000049"
     CDS             44150..44773
                     /gene="rplD"
                     /locus_tag="VVK04_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU3988775.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44773..45069
                     /locus_tag="VVK04_000050"
     CDS             44773..45069
                     /locus_tag="VVK04_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU3988776.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            45087..45920
                     /gene="rplB"
                     /locus_tag="VVK04_000051"
     CDS             45087..45920
                     /gene="rplB"
                     /locus_tag="VVK04_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU3988777.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            46024..46305
                     /gene="rpsS"
                     /locus_tag="VVK04_000052"
     CDS             46024..46305
                     /gene="rpsS"
                     /locus_tag="VVK04_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU3988778.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            46317..46661
                     /gene="rplV"
                     /locus_tag="VVK04_000053"
     CDS             46317..46661
                     /gene="rplV"
                     /locus_tag="VVK04_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU3988779.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            46674..47327
                     /gene="rpsC"
                     /locus_tag="VVK04_000054"
     CDS             46674..47327
                     /gene="rpsC"
                     /locus_tag="VVK04_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU3988780.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            47331..47744
                     /gene="rplP"
                     /locus_tag="VVK04_000055"
     CDS             47331..47744
                     /gene="rplP"
                     /locus_tag="VVK04_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU3988781.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            47754..47960
                     /locus_tag="VVK04_000056"
     CDS             47754..47960
                     /locus_tag="VVK04_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU3988782.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47985..48245
                     /gene="rpsQ"
                     /locus_tag="VVK04_000057"
     CDS             47985..48245
                     /gene="rpsQ"
                     /locus_tag="VVK04_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU3988783.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            48271..48639
                     /gene="rplN"
                     /locus_tag="VVK04_000058"
     CDS             48271..48639
                     /gene="rplN"
                     /locus_tag="VVK04_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU3988784.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            48717..49022
                     /gene="rplX"
                     /locus_tag="VVK04_000059"
     CDS             48717..49022
                     /gene="rplX"
                     /locus_tag="VVK04_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU3988785.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            49046..49588
                     /gene="rplE"
                     /locus_tag="VVK04_000060"
     CDS             49046..49588
                     /gene="rplE"
                     /locus_tag="VVK04_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU3988786.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            49606..49875
                     /gene="rpsN"
                     /locus_tag="VVK04_000061"
     CDS             49606..49875
                     /gene="rpsN"
                     /locus_tag="VVK04_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU3988787.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            50160..50558
                     /gene="rpsH"
                     /locus_tag="VVK04_000062"
     CDS             50160..50558
                     /gene="rpsH"
                     /locus_tag="VVK04_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU3988788.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            50750..51286
                     /gene="rplF"
                     /locus_tag="VVK04_000063"
     CDS             50750..51286
                     /gene="rplF"
                     /locus_tag="VVK04_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU3988789.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            51370..51726
                     /gene="rplR"
                     /locus_tag="VVK04_000064"
     CDS             51370..51726
                     /gene="rplR"
                     /locus_tag="VVK04_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU3988790.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            51744..52238
                     /gene="rpsE"
                     /locus_tag="VVK04_000065"
     CDS             51744..52238
                     /gene="rpsE"
                     /locus_tag="VVK04_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU3988791.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            52210..52434
                     /gene="rpmD"
                     /locus_tag="VVK04_000066"
     CDS             52210..52434
                     /gene="rpmD"
                     /locus_tag="VVK04_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU3988792.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            52579..53019
                     /gene="rplO"
                     /locus_tag="VVK04_000067"
     CDS             52579..53019
                     /gene="rplO"
                     /locus_tag="VVK04_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU3988793.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSVEEAITAKGGSVEVI"
     gene            53032..54342
                     /gene="secY"
                     /locus_tag="VVK04_000068"
     CDS             53032..54342
                     /gene="secY"
                     /locus_tag="VVK04_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU3988794.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            54493..55131
                     /locus_tag="VVK04_000069"
     CDS             54493..55131
                     /locus_tag="VVK04_000069"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU3988795.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            55248..55466
                     /gene="infA"
                     /locus_tag="VVK04_000070"
     CDS             55248..55466
                     /gene="infA"
                     /locus_tag="VVK04_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU3988796.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            55491..55607
                     /gene="rpmJ"
                     /locus_tag="VVK04_000071"
     CDS             55491..55607
                     /gene="rpmJ"
                     /locus_tag="VVK04_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU3988797.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            55625..55990
                     /gene="rpsM"
                     /locus_tag="VVK04_000072"
     CDS             55625..55990
                     /gene="rpsM"
                     /locus_tag="VVK04_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU3988798.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            56008..56391
                     /gene="rpsK"
                     /locus_tag="VVK04_000073"
     CDS             56008..56391
                     /gene="rpsK"
                     /locus_tag="VVK04_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU3988799.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            56434..57369
                     /locus_tag="VVK04_000074"
     CDS             56434..57369
                     /locus_tag="VVK04_000074"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU3988800.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            57381..57767
                     /gene="rplQ"
                     /locus_tag="VVK04_000075"
     CDS             57381..57767
                     /gene="rplQ"
                     /locus_tag="VVK04_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU3988801.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            58032..58298
                     /locus_tag="VVK04_000076"
     CDS             58032..58298
                     /locus_tag="VVK04_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU3988802.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            58308..59645
                     /locus_tag="VVK04_000077"
     CDS             58308..59645
                     /locus_tag="VVK04_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU3988803.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59889..60581
                     /locus_tag="VVK04_000078"
     CDS             59889..60581
                     /locus_tag="VVK04_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU3988804.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(60684..62329)
                     /locus_tag="VVK04_000079"
                     /pseudo
     CDS             complement(60684..62329)
                     /locus_tag="VVK04_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(62319..63347)
                     /locus_tag="VVK04_000080"
                     /pseudo
     CDS             complement(62319..63347)
                     /locus_tag="VVK04_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810335.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(63422..64543)
                     /locus_tag="VVK04_000081"
                     /pseudo
     CDS             complement(63422..64543)
                     /locus_tag="VVK04_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(64760..64957)
                     /locus_tag="VVK04_000082"
     CDS             complement(64760..64957)
                     /locus_tag="VVK04_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU3988805.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKHLHISPKELKLLGRIVK"
     gene            complement(65032..65808)
                     /locus_tag="VVK04_000083"
     CDS             complement(65032..65808)
                     /locus_tag="VVK04_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU3988806.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            65930..66676
                     /locus_tag="VVK04_000084"
     CDS             65930..66676
                     /locus_tag="VVK04_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU3988807.1"
                     /translation="MKRLEQIIKLVSEHEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            66689..67669
                     /locus_tag="VVK04_000085"
     CDS             66689..67669
                     /locus_tag="VVK04_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU3988808.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDTPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67864..68184
                     /locus_tag="VVK04_000086"
     CDS             67864..68184
                     /locus_tag="VVK04_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU3988809.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            68230..68538
                     /locus_tag="VVK04_000087"
     CDS             68230..68538
                     /locus_tag="VVK04_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU3988810.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            68555..69853
                     /locus_tag="VVK04_000088"
     CDS             68555..69853
                     /locus_tag="VVK04_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU3988811.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            70004..72442
                     /locus_tag="VVK04_000089"
     CDS             70004..72442
                     /locus_tag="VVK04_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU3988812.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKTDLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            72461..73129
                     /locus_tag="VVK04_000090"
     CDS             72461..73129
                     /locus_tag="VVK04_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU3988813.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            73147..74235
                     /locus_tag="VVK04_000091"
     CDS             73147..74235
                     /locus_tag="VVK04_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU3988814.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            74690..77191
                     /locus_tag="VVK04_000092"
     CDS             74690..77191
                     /locus_tag="VVK04_000092"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU3988815.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVANYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVAEAAYTEDGLHVNSDFLDGLNKEEA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTRADGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            77386..78081
                     /locus_tag="VVK04_000093"
     CDS             77386..78081
                     /locus_tag="VVK04_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3988816.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            78093..78509
                     /locus_tag="VVK04_000094"
     CDS             78093..78509
                     /locus_tag="VVK04_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3988817.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(79324..79416)
                     /locus_tag="VVK04_000095"
     CDS             complement(79324..79416)
                     /locus_tag="VVK04_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU3988818.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            79577..80548
                     /gene="ruvB"
                     /locus_tag="VVK04_000096"
     CDS             79577..80548
                     /gene="ruvB"
                     /locus_tag="VVK04_000096"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU3988819.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            80637..81101
                     /locus_tag="VVK04_000097"
     CDS             80637..81101
                     /locus_tag="VVK04_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU3988820.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            81332..82090
                     /locus_tag="VVK04_000098"
     CDS             81332..82090
                     /locus_tag="VVK04_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU3988821.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            82099..82902
                     /locus_tag="VVK04_000099"
     CDS             82099..82902
                     /locus_tag="VVK04_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU3988822.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            82924..84183
                     /gene="rseP"
                     /locus_tag="VVK04_000100"
     CDS             82924..84183
                     /gene="rseP"
                     /locus_tag="VVK04_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU3988823.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            84196..86049
                     /locus_tag="VVK04_000101"
     CDS             84196..86049
                     /locus_tag="VVK04_000101"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU3988824.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            86149..87528
                     /gene="bglA"
                     /locus_tag="VVK04_000102"
     CDS             86149..87528
                     /gene="bglA"
                     /locus_tag="VVK04_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU3988825.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGICLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            87721..89529
                     /gene="glmS"
                     /locus_tag="VVK04_000103"
     CDS             87721..89529
                     /gene="glmS"
                     /locus_tag="VVK04_000103"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU3988826.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(89667..89744)
                     /locus_tag="VVK04_000104"
                     /pseudo
     CDS             complement(89667..89744)
                     /locus_tag="VVK04_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            89801..90850
                     /locus_tag="VVK04_000105"
     CDS             89801..90850
                     /locus_tag="VVK04_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU3988827.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(90950..94765)
                     /gene="spuA"
                     /locus_tag="VVK04_000106"
     CDS             complement(90950..94765)
                     /gene="spuA"
                     /locus_tag="VVK04_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU3988828.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQE
                     AQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLG
                     FLLKNKKEN"
     gene            95182..95595
                     /gene="rpsL"
                     /locus_tag="VVK04_000107"
     CDS             95182..95595
                     /gene="rpsL"
                     /locus_tag="VVK04_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU3988829.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            95615..96085
                     /gene="rpsG"
                     /locus_tag="VVK04_000108"
     CDS             95615..96085
                     /gene="rpsG"
                     /locus_tag="VVK04_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU3988830.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            96510..98591
                     /gene="fusA"
                     /locus_tag="VVK04_000109"
     CDS             96510..98591
                     /gene="fusA"
                     /locus_tag="VVK04_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU3988831.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            98695..103086
                     /locus_tag="VVK04_000110"
     CDS             98695..103086
                     /locus_tag="VVK04_000110"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU3988832.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVSRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFINKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            103188..103451
                     /locus_tag="VVK04_000111"
     CDS             103188..103451
                     /locus_tag="VVK04_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU3988833.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            103444..103722
                     /locus_tag="VVK04_000112"
     CDS             103444..103722
                     /locus_tag="VVK04_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU3988834.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            103743..103895
                     /locus_tag="VVK04_000113"
     CDS             103743..103895
                     /locus_tag="VVK04_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988835.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            103917..105158
                     /locus_tag="VVK04_000114"
     CDS             103917..105158
                     /locus_tag="VVK04_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU3988836.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENVGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            105168..105398
                     /locus_tag="VVK04_000115"
     CDS             105168..105398
                     /locus_tag="VVK04_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU3988837.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            105711..106433
                     /locus_tag="VVK04_000116"
     CDS             105711..106433
                     /locus_tag="VVK04_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU3988838.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            106650..107984
                     /gene="pepC"
                     /locus_tag="VVK04_000117"
     CDS             106650..107984
                     /gene="pepC"
                     /locus_tag="VVK04_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU3988839.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAVLNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
BASE COUNT        32217 a        19956 c        24129 g        31750 t
ORIGIN      
        1 aatagtccat gctgtggctg gattcttttc agcctactta tactcttcga aactctcttc
       61 aaaccacgtc agcttcacct tgccgtaggt atggttactg acttcgtcag ttctatccac
      121 aacctcaaaa cagtgttttg agctgacttc atcagttcta tccacaacct caaaacggtg
      181 ttttgagcaa cctgcggcta gtttcctagt ttgctctttg attttcattg agtattatta
      241 agacaatatg aggagaaaga tgaaagaaaa aggattttag gagggggcgc aggcagccat
      301 gccaacggct cttggctatg tcagtatcgg cctggcctgt ggaattatcg gtgcgcccta
      361 tgtgacacct gttgagatgg gcttgatgag tctctttgtt tatgctggga gtgcccagtt
      421 tgccatgttg gcactgattg tggttcaagc tcctgtggca gctattgcta tgacggtttt
      481 tctaatcaac ttgcgtctct ttttgttgag tttacacgca tcgacttatt tccgtcatac
      541 cagtctttgg tacaatatcg gtatgtctag tatcttgaca gatgagacct atggcgtttt
      601 gatgggtgaa ttggcccata cagacaaggt aaatcctatg tggatgcacg gaaacaatct
      661 taacagctat gtggcttggt ttgtggggac agtagtcgga acggctctgg gtggcctgct
      721 accaaatcca gaaatctttg ccttgattct ttcaagtgta gtgacaggta aggttgggag
      781 ccttcctcaa attaaatggc tagacttctt agccgtcttt ccaacagctt gggtagcctt
      841 tcgctaccgc aatctagtcg gaacagttct ctttggagta gtcttgattg ccgtcttgcg
      901 tttggtcttt taaatcagcc ataaagaaaa cctatcacag atatatatat catataatgg
      961 tgtaaatgat ttttttctgt taagattata aggtattcta ttttggagga aatgacatga
     1021 aaaaaatcgt taaatactca tctcttgctg ccctagggct tgttgctgca ggtgtgctag
     1081 cagcttgctc aggtggtgct aagaaagaag gacaagcagc tagcaagaaa gaaattattg
     1141 ttgcaactaa ttcttcacca aaaccattca actatgaaga aaatggcgaa ttgactggtt
     1201 acgagattga agtcgttcgc gctatcttta aagactctga caagtatgat gtcaagtttg
     1261 agaagacaga gtggtcaggt gtctttgcgg gtcttgacgc tgaccgttac caaatggctg
     1321 ttaacaatat cagctacact aaagaacgtg cggagaaata cctttatgca gccccaactg
     1381 ttaaagaccc taacgttctt gtagtcaaga aagacgattc tagcatcaaa tcgcttgatg
     1441 atgttggtgg aaaatcaaca gaagttgttc aaggaacaac atctgctaaa cagttagaag
     1501 actacaacaa acaacactca gataatccaa ctatccttaa ctatactaaa gcaaacttac
     1561 aacaaatcat gggccacttg agcgatggtc agtttgacta caagattttt gataaaatca
     1621 ctgttgaaac agtcatcaag aaccaaggtt tggacaactt gaaagtcatc gatcttccaa
     1681 gcgaccaaca accgtacgtt tacccacttc ttgctaaagg tcaagatgag ttgaaaacat
     1741 ttgtagacaa acgtatccaa gaactctaca aagacggaac tcttgaaaaa ttgtctaaac
     1801 aattcttcgg agacacttac ctaccggcag aagctgatat taaataattt cttgaaatca
     1861 tccattctga gtaagatggg tgatttttca gttcgctact gcaatctagt cggaacagtt
     1921 ctctttggag tggtcttgat tgccatcttg cgtttggtct tttaaattac ccataaaaaa
     1981 aacttatcac agagatagat atcatataat ggcgtaaatg ctctttttct gttaagatta
     2041 taaggtattc tattttggag gaaatgacat gaaaaaaatc gttaaatact catctcttgc
     2101 tgccctagga cttgttgctg caggtgtgct tgcggcttgc tcaggtggtg ctaagaaaga
     2161 aggagaagca gctagcaaga aagaaatcat cgttgcaacc aatggatcac caaggccatt
     2221 tatctatgaa gaaaatggcg aattgactgg ttacgagatt gaagtcgttc gcgctatctt
     2281 taaagattct gacaaatatg atgtcaagtt tgaaaagaca gaatggtcag gtgtctttgc
     2341 tggtcttgac gctgaccgtt acaatatggc tgtcaacaat cttagctaca ctaaagaacg
     2401 tgcggagaaa tacctctatg ccgcaccaat tgcccaaaat cctaatgtcc ttgtcgtgaa
     2461 gaaagatgac tctagtatca agtctctcga tgatatcggt ggaaaatcga cggaagtcgt
     2521 tcaagccact acatcagcta agcagttaga agcatacaat gctgaacaca cggacaaccc
     2581 aactatcctt aactatacta aggcagactt ccaacaaatc atggtacgtt tgagcgatgg
     2641 acaatttgac tacaagattt ttgataaaat cggtgttgaa acagtgatca agaaccaagg
     2701 tttggacaac ttgaaagtta tcgaacttcc aagcgaccaa caaccgtacg tttacccact
     2761 tcttgctcaa ggtcaagatg agttgaaatc atttgtagac aaacgcatca aagaacttta
     2821 taaagatgga actcttgaaa aattgtctaa acaattcttc ggagacactt atctaccggc
     2881 agaagctgat attaaataat ttcttgaaat catccattct gagtaaggtg ggtggtttct
     2941 cagtttttag ggatatagtt ttaaactata tatctgacta tctaataaca atttgtgaaa
     3001 tcaaacaaat tgtgagatac tagtacggta ttatttttaa ggagaaagaa tcatgaaaat
     3061 caaaaaatgg cttggcctag cagcccttgc tacagtcgca ggtttggctc ttgcagcttg
     3121 cggaaactca gaaaagaaag cagacaatgt aacaactatc aaaatcgcaa ctgttaaccg
     3181 tagcggttct gaagaaaaac gttgggacaa aatccaagaa ttggttaaaa aagacggaat
     3241 taccttggaa tttacagagt tcacagacta ctcacaacca aacaaagcaa ctgctgatgg
     3301 cgaagtagat ttgaacgctt tccaacacta taacttcttg aacaactgga acaaagaaaa
     3361 cggaaaagac cttgtagcga ttgcagatac ttacatctct ccaatccgcc tttactcagg
     3421 tttgaatgga agtgccaaca agtacactaa agtagaagac atcccagcaa acggagaaat
     3481 cgctgtaccg aatgacgcta caaacgaaag ccgtgcgctt tacttgcttc aatcagctgg
     3541 cttgattaaa ttggatgttt ctggaactgc tcttgcaaca gttgccaaca tcaaagaaaa
     3601 tccaaagaac ttgaaaatca ctgaattgga cgctagccaa acagctcgtt cattgtcatc
     3661 agttgacgct gccgttgtaa acaatacctt cgttacagaa gcaaaattgg actacaagaa
     3721 agcacttttc aaagaacaag ctgatgaaaa ctcaaaacaa tggtacaaca tcattgttgc
     3781 gaaaaaagat tgggaaacat cacctaaggc tgatgctatc aagaaagtaa tcgcagctta
     3841 ccacacagat gacgtgaaaa aagttatcga agaatcatca gacggtttgg atcaaccagt
     3901 ttggtaataa gaaacaggga ggtgggagag agaattccac ctcttgcttt tgtatagagc
     3961 acggagtgta aagaagacta ttcgttcata gaaaggtaga gagaatatgg tttttcctag
     4021 cgaacaagaa cagattgaaa aatttgaaaa ggatcatgta gcccagcatt attttgaggt
     4081 tttgcgtacc ttgatttcta agaaatcagt ctttgcccag caggttggac tcaaggaagt
     4141 cgcaaattat ctgggtgaga ttttcaagcg tgttggagct gaagtggaga ttgatgagag
     4201 ctatacagcg ccctttgtca tggcacattt caagagttcg cgtccagatg ccaagacctt
     4261 gattttctat aaccactatg acactgtgcc agcggatggg gatcaggtct ggacagagga
     4321 tccttttacg ctttcggtcc gcaatggctt catgtatggg cgtggggttg atgacgacaa
     4381 gggtcatatc acagctcgct tgagtgcttt gagaaaatat atgcagcacc atgatgattt
     4441 acctgtcaat atcagcttta tcatggaggg agcggaggaa tcggcttcaa cagacctaga
     4501 taagtatttg gaaaagcatg cagacaaact ccgtggggcg gatttgttgg tctgggaaca
     4561 agggaccaaa aatgccttgg aacagctgga aatttctggt ggcaataagg ggattgtgac
     4621 ctttgatgcc aaggtaaaaa gcgctgatgt ggatatccac tcgagttatg gtggtgttgt
     4681 ggaatcagct ccttggtatc tcctccaagc cttacagtct cttcgtgctg cggatggccg
     4741 tatcttggtt gaaggcttgt acgaagaagt acaagagccc aatgaacgag aaatggcctt
     4801 gctagaaact tatggtcaac gaaacccaga ggaagttagt cggatttatg gattggagtt
     4861 gcctctctta caggaggagc ggatggcctt tctaaaacgt ttctttttcg agccagcgct
     4921 taatatcgaa ggaatccagt ctggttatca aggtcagggt gttaagacta ttttacctgc
     4981 agaagccagt gccaagctag aggttcgtct ggttccgggc ctagaaccgc atgatgttct
     5041 ggaaaaaatt cggaaacagc tagacaaaaa tggctttgat aaggtagaat tatactatac
     5101 cttgggagag atgagctatc gaagcgatat gagcgcacca gccattctca atgtgatcga
     5161 gttggccaag aaattctatc cacagggcgt ttcagtcttg ccgacgacag cggggacagg
     5221 acctatgcat acggtctttg atgccctaga ggtaccaatg gttgcattcg gtctaggaaa
     5281 tgccaatagc cgagaccacg gtggagatga aaatgtgcga atcgctgatt attacaccca
     5341 tatcgaatta gtagaggagc tgattagaag ctatgagtag agatattatc aagttagatc
     5401 agatcgatgt gacttttcac caaaagaaga gaaccattac agcggttaag gatgtgacca
     5461 ttcacatcca agaaggggat atctacggaa tcgttggata ttctggagca gggaaatcaa
     5521 cccttgtacg ggtgattaat ctcttgcaaa aaccatctgc agggaaaatt accattgacg
     5581 acgatgtgat ttttgacggc aaggtgacct tgacggcaga gcagttgcgt cgtaaacgtc
     5641 aagatatcgg aatgattttc cagcatttta acctgatgag ccaaaagaca gcagaggaga
     5701 atgtagcctt tgcccttaaa cactctgaac tcagcaagga agaaaagaag gctaaagtag
     5761 ctaagttgtt ggacttggtt ggtttggcag atcgtgctga aaactaccct tcacaactat
     5821 ctggagggca aaaacagcgt gtggcaattg cgcgtgcctt ggccaatgat ccaaaaatct
     5881 tgatttcaga cgagtcaact tctgcccttg atccgaagac aaccaagcag attttggcct
     5941 tgttgcaaga tttgaaccaa aaattaggct tgactgttgt cttgattacg catgaaatgc
     6001 agattgtcaa agacattgcc aaccgtgtgg cggttatgca ggatgggcat ttgattgaag
     6061 agggtagtgt gcttgaaatc ttctcagacc ctaaacaacc tttgactcaa gactttatct
     6121 caacagctac aggtattgac gaagccatgg tcaaaatcga gaagcaagaa atcgtggaac
     6181 acttgtctga aaacagtctc ttggtgcaac tcaagtacgc tggagcttca acagacgagc
     6241 cacttttgaa tgaattgtac aagcattacc aagtaatggc taatattctc tatgggaata
     6301 tcgaaattct cgatggtact cctgttggag aattggtggt ggttttgtca ggtgaaaaag
     6361 cagcgttggc aggtgcccaa gaagccattc gtcaagcagg tgtacaacta aaagtattga
     6421 agggagtaca gtaagatgga atcattgatt caaacctatt taccaaatgt ctataaaatg
     6481 ggttgggctg gtcaggcagg ctggggaacg gctatctact taactcttta tatgacagtt
     6541 ctttccttca ttatcggagg cttcttgggg ctagtggcag gtctctttct cgtcttgaca
     6601 gcgccaggtg gtgtcttgga gaataaagtc gtattctgga ttttagacaa aattacctca
     6661 atttttcgtg cggttccctt tatcatcctc ttggcaatct tgtcaccact ttctcacttg
     6721 attgttaaaa caagtatcgg gccaaatgca gcccttgtcc cactttcttt tgcagtcttt
     6781 gccttctttg cccgtcaggt gcaggttgtc ttggctgaat tggatggcgg tgtcattgag
     6841 gcggctcaag cgagcggagc gactttctgg gacatcgtgg gtgtttacct atcagaaggt
     6901 cttccagatt tgatccgtgt gacgactgtg accttgattt cccttgttgg ggaaacagct
     6961 atggccggtg cggttggagc tggtggtatc ggtaacgtag ccatcgctta tggatttaac
     7021 cgctacaatc acgatgtgac catcttggca accatcatta tcattttgat tatctttgca
     7081 atccaattct tgggagattt cttgactaag aaattgagcc ataaataaaa aagagccgtg
     7141 tggctctttt taactgatca gattttctgg gcaaattttt tactcaaggc ttgtccaatc
     7201 aaggcaccca ctagggctcc gatgacaata cttgcgataa atagaaggac agttccaggg
     7261 tttggagtga ccatgatacg gtcgatatat tcttgggatt ttcctcttgc cagaagagta
     7321 gccatatagg ctttgggcgc aatccacata agcaagattg gtcctgttgt actaaaggcg
     7381 aaaataatga aagaaaggaa gttctttgtt ttgtccttgt attttcctaa atgagctact
     7441 tcatctgcta ggaggccaca gataattcca ggaaggaagg aaccagcacc gtgtttagtt
     7501 cccaagaaaa agaaggcaat gacaaggccg atagtggtaa tggctccaaa gcgcggaact
     7561 tttgcgacta ggatcatata gacgctaccg ccgacaaggg cagtaaaggc aggcgcataa
     7621 aacatgtttc cagtttggtc aaagagattg cccaaaagga caccaatccc catgcagagg
     7681 aagtaaagaa ctgcaaaaag cagtgtagtt aagatagatt tcttcatgaa ttgtctcctg
     7741 ataatttttt cacaattctc attttaccat ggtttggtgg gattgtaaat ggatactaga
     7801 agtttttgaa aacgcttgaa atatgatata atggtttcat agttattttt aggggaatat
     7861 catgggtaga tttttagact ttgtctttaa tcgtttcttt ttagggatga ttgcgacagc
     7921 cttcttttgg ctattaactt tagcaggagg gattatcctt ggtctagcgc cggctagtgc
     7981 caccttgatg agcttatatg cagaacatgg ttatagcttt cgggaataca gtttgaagga
     8041 ggcttggtct ctttacaagc aaaattttgt ctcaagcaac ctgattttct atagcttttt
     8101 aggtgtgggt ctagttttga cctatggttt gtatctcttg gtgcaattgc ctcatcagac
     8161 cattgttcat ttgattgcga cccttttgaa tgtcctagta gttgccctga tctttttggc
     8221 ttatacagta tctttaaaat tacaagttta ttttgccttg tcctatcgaa atagtctcaa
     8281 attatccttg attggcatct ttatgagtct agcagctgtg gccaaggttc tccttgggac
     8341 tgtgctactt gtagcaattg gttactatat gcctgccctg ctattttttg taggaattgg
     8401 gatgtggcat ttctttatca gtgatatgtt ggaacctgtc tatgaaatca tccatgaaaa
     8461 attggcgaca aaatagaatg aagcagtttt ggctacatac gcttctaaga acctatagtt
     8521 cagtgatgat cattatcatt gcgagttttg caatcttact ctcttacgct gactgggatt
     8581 cacgtgaaaa ggaagcccag agagtagccc agcgtgtaac tgctagaaca gtgagtgaaa
     8641 ttgaatatta ccatagagag tcaacccaga tagctcaggc tttagttgaa aaccaagctc
     8701 gtattgaggg aatctataaa tactttagcc ttagcatgcc agactatttt tactggcaat
     8761 tagagcggaa agcttcgcct tatatatcag tctctctgta tgaaaatgtt gatgacctct
     8821 atgttcgaaa tgattttgta actggagtgg ccattgcttt tcaagattac aaggaagtct
     8881 atgtttctac taaagacaaa cgtagtggag aaaaaatcag ggctgaggat ttcaaaccag
     8941 caggaaatag ttttgccatt ccggtgtcag atccagtgtc agatcaagat ttaggagtga
     9001 tttacatctc cttggatcct gctgttttat accatgccat tgataatact agaggccata
     9061 ctccgatggc agtaacagtg acctcacctt ttgatacgga gatttttcat attggtgaga
     9121 cagttgatag ggagagtgaa aattggctag ttggcttaac ttctcatgga tatcaggttc
     9181 aggtggcagt tcctaaaaac tttgttttac aaggaacagt gactagctct gctttgattg
     9241 tgggtttgag ccttctcttt attgtcattc tttatctgac tttgaggcag acttttgcta
     9301 attaccaaaa gcaggtagtg gatttagtag aatccattca agtcattgct caaggcgaag
     9361 aggggcgtcg gattgacatt tccgaaaaag atcaggaatt actcctaatc gcggagacga
     9421 ccaatgatat gttggatcga ttggaaaaga atatccatga tatttaccag ttagagctta
     9481 gtcaaaaaga tgccaatatg cgagccttgc aggcgcaaat caatcctcat tttatgtata
     9541 atacgctgga gttcttgcgc atgtatgcag ttatgcagag tcaagatgag ttggcagata
     9601 tcatttatga attcagtagt ctcttgcgta acaatatttc cgacgaaaga gagacccttc
     9661 tcaaacagga attagaattt tgccgtaaat acagctatct ctgcatggtt cgctatccca
     9721 agtccattgc ctatggtttc aagatagatc cagagttaga gaatatgaag attcccaagt
     9781 ttaccttgca accgctggta gaaaactatt tcgcgcatgg tgttgaccac aggcggacag
     9841 ataatgtgat tagcatcaag gctcttaaac aggatggttt tgtggaaatt ttggtggtcg
     9901 ataatggtag aggaatgtcg gctgaaaagt tggcaaatat ccgagaaaaa ttaagtcaga
     9961 aatattttga acaccaagcc agctacagtg atcaaaggca gtctatcggg attgtcaatg
    10021 tacacgagcg ttttgtgctc tattttggag accgctatgc cattactata gagtctgcag
    10081 agcaagccgg tgttcagtat cgtattacaa ttcaagatga gtagaaaggg agaaaatgta
    10141 taaagtatta ttagtagatg atgagtacat ggtgacagaa ggtctgaagc gtttgattcc
    10201 ctttgataag tgggatatgg aggtcgtcgc aacagccagt catgccgatg aagctctaga
    10261 atatgttcag gaaaatcctg tcgatgtcat catttccgat gtcaatatgc cagacaaaac
    10321 agggcttgat atgattcggg agatgaaaga gatcttacca gatgctgcct atatcctgct
    10381 ctcaggttat caggagtttg attatgtaaa aagagcaatg aaccttagtg tggtggacta
    10441 tttggtcaag cctgttgata aggtagagct gggaaatctg ctggagaaga ttgcaggtca
    10501 gctcggcgag agagggaaga aaagtcagac tcttagtcaa gaattagacg aggctggatt
    10561 tgttagttat ttaggggata aggagaattg gtggataggt ctatccaagg aaaaacaagg
    10621 ttccttcacc attccctact atgtcttggg tcaagactgg cagattttca tttctggcca
    10681 ccccctagat ggtttagtcg ttacaccttt tgaagctcct tatcaagaac actttgaacg
    10741 ctggaagctg aatgctgaga aaaccctctt ttacggttct gtaaatctgc agcagtctga
    10801 gagtctcttt gcctattacg aaccgattta tagggttatc attcagggaa atctcaatca
    10861 aatcgtagaa gagttaaatc tcttggagaa ggtagttctt gaaaatacac ctcgtgtttc
    10921 gattactaaa cagcttttta tccagtttgt catggatgtt ttccatttat ttgaacatct
    10981 caaagctgat gatatgacgg acattgtcaa aaccattcat gctattcaat ccttcgatga
    11041 attggtttct tatatcaagg aaactctgat cagctttttc ggtcaatacc gtatgaatga
    11101 aaatgtggtc agtgtgctgg aagtcattgg tcgtgattac caaaaagagc tttccctcaa
    11161 ggatatcagt aaggccctct ttatcaatcc tgtctatcta gggcagttga ttaagcgtga
    11221 aaccgattcg acttttgcag agttactaaa caaacaacgt attaaggctg cccagcagct
    11281 cttgctttca accagtgaca gtatcgaaga tatttgttat gctgttggtt acagtaacct
    11341 tggatatttc tataaagttt tccgaaaatt gtgcggaaaa tcgccaaaag cctaccgaaa
    11401 acaggtagaa actatactat aagatttgta ttcctttaca aaaggtgcta taatattatc
    11461 aggaggtcct atcatgaaaa agaaaccaat ttatctatgg gttttgctaa tcttgtctgc
    11521 ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta aagaagccct
    11581 tcgtgctgct cagaaacaag ttgcaggggt caatgctcag caattagaag accagcttaa
    11641 ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt tgattgtgct
    11701 atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt tgcaatatgc
    11761 aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt atggctatgt
    11821 tggtttacaa gacgctgtgc agttggttca agatgagagc atgcgtttga cagtgagtat
    11881 tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc tagcccttgt
    11941 cttctataag atgtggcgac aacagaaagc cttggcagaa gaagaggaaa cagaagagct
    12001 tgcctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg ttttttgatt
    12061 atagataaaa tcatggaggt acatatgaag acaatttctt tagtttatat tagtttgagt
    12121 ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca gtacaaaggg
    12181 attgaggttc aaaagattca tatcaaggat ttggtcaagg aaggcaaaaa tttctatgaa
    12241 atggaccatc cctatgtcgc ttttttgccg acctatctcg aaggtgggaa tggcgtggat
    12301 aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta tggtaacaat
    12361 gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa ccaatactgc
    12421 ctaacagcca agcaatacag tcaacgcttt ggcttccctg tattggctga ctttgaaatg
    12481 cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt gtatgagttg
    12541 gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct agtcgcaggt
    12601 tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag agattctcga
    12661 atagtataaa gttcttataa gaggtggttg aagttgttca actgtttttt gagtataaac
    12721 agtttttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt cttatgcttt
    12781 ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt catctcgcgc
    12841 ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg gcgaagccaa
    12901 agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga tttttgtttt
    12961 cacgcgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg aaagatccaa
    13021 tcatggcaaa gcggagcatg gttgaaacct gaccagcgaa gaacttgata atgacgatac
    13081 cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattgtcc tctttttgac
    13141 tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata acagttataa
    13201 ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac cattcgccaa
    13261 gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca gcttcaaccg
    13321 cctgccctgt aggatattga atcagtgctc ccagtgccac aaagaagacg gctaggatag
    13381 ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta aagttgacgg
    13441 tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata ggagccggca
    13501 tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt gtcttctcga
    13561 caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgcc agaacagtcg
    13621 caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg tagcctccaa
    13681 agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta atgctaagtc
    13741 caatcattgg gaaggcactg gcgatgatag ctgagcacag aatggcaaca ccagccgtgt
    13801 tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt tttccttttt
    13861 cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca ccaaaacgga
    13921 aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac caaccgtaag
    13981 aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca gttgccatta
    14041 ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt aaggaaatag
    14101 cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata tgtaatctat
    14161 attctacaaa aaattttgga aaaatgcaag aatattttga aaaaagatag aaaatttaca
    14221 aagaaaatct gaaataactg ttatgatata gcagattgaa actagaatag tacacctttg
    14281 cttctaaaac attgttagaa atcgatttga ctgtcctgaa cgatttatcc tgttcttatt
    14341 tcatttcact atagtaaggt gcagcaggat aaagaaaaac cgagaagttt ctttctcgga
    14401 tttgcttatt atgaggttcc tattttctat gctccaagag ttgattgatg tgatctactt
    14461 ttttagcctc tcttttatag agaatagccc agatgatgag atagacaatc gcaaactcga
    14521 taatgagctg gaggtagaaa atccagtgga aagggaacca accagcaaga gttgctagtg
    14581 ggacaaagcc agccagcata aggaagaaat gagtcagagt ggcacgaagc atgctccagt
    14641 cacggctgaa taagcggttg ccaaagttga agagcatacc gatggctgcc cagataagtg
    14701 tgcagtagag caagaccagg gcaccgtgaa cctgatgctg atccatcact tggccgatga
    14761 gagagtaggg atttagtggt gcgtaggtat ttggtgcata aatgagtgaa aagaggatgg
    14821 agaggatgag gccgataaga acaccggcag ctgcatcgtg aaatacttgt tttttcatag
    14881 ttctaatttc tccttgatgg tttttagata acggcgtgaa gagtaggtga agctttcgtt
    14941 tttcaagaaa atttctacca gaccgtttgg cgtgagcttg aggtgagaga tggaatcgat
    15001 attgatgatt tctgattggg aaatttggat aaaattgctt ggcaagagtt taagaacctg
    15061 atagagtcgc aaatcaatgc tgtaggtctg actcgcggtt tctgctagaa ccttccgatt
    15121 ctcgatatag aagcgctgaa tcttgccaat ctcaactaga tagacctgat catcgatttt
    15181 ccctttgatt ttttctcttt ggtccagatt ttctgcgaac tcgatgactt tctggacttt
    15241 ttcggtttct tgaggtgctt ggacaatcag cttttcctcc tcgtaagtct cactaatctg
    15301 tagttctact ttcataaatt tctctccttg tttttcatac aaaattaatc tcacttcttg
    15361 tacaccttta ttaatactct tcaaaaatct cttcaaacca cgtcagcgtc gtcttgccgt
    15421 aggatagttg ttgactttgt cagttttatc tacaacctca aaacagtgtt ttgagctttc
    15481 tgcgcctagc tttctagttt gttctttgat ttttattgag tataccacta ttttacgccc
    15541 tttggcaagg tactttgtct atgtggaggg attgggctcc tatgtggtgg agcttttctg
    15601 ttctttctga aatatggtat aatagcacta attaatttct aggaaaatag atacagaaag
    15661 gggctgaaag atgtctcata ttattgaatt gccagagatg ctggcaaacc aaatcgcggc
    15721 tggagaggtc attgaacgtc ctgccagtgt ggtcaaagag ttggtagaaa atgccattga
    15781 cgcgggctct agtcagatta tcattgagat tgaggaagct ggtctcaaga aggttcaaat
    15841 cacggataac ggtcatggaa ttgcccacga tgaggtggag ttggccctgc gtcgccatgc
    15901 gaccagtaag ataaaaaatc aagcagatct ctttcggatt cggacgcttg gttttcgtgg
    15961 tgaagccttg ccttctattg cgtctgttag tgtcttgact ctgttaacgg cggtggatgg
    16021 tgctagtcat ggaaccaagt tagtcgcgcg cgggggtgaa gttgaggaag tcatcccagc
    16081 gactagtcct gtgggaacca aggtttgtgt ggaggatctc tttttcaaca cgcctgcccg
    16141 tctcaagtat atgaagagcc agcaagcgga gttgtctcat atcattgata ttgtcaaccg
    16201 tctgggcttg gcccatcctg agatttcttt tagcttgatt agtgatggca aggaaatgac
    16261 gcggacagca gggactggtc aattgcgcca agcaatcgca gggatttacg gtttggtcag
    16321 tgccaagaag atgattgaaa ttgagaactc tgacctagat ttcgaaattt caggttttgt
    16381 gtccttacct gagttgactc gggctaaccg caattatatc agcctcttca tcaatggccg
    16441 ttatatcaag aacttcctgc tcaatcgtgc tattttggat ggttttggaa gcaagcttat
    16501 ggttggacgt tttccactgg ctgtcattca catccatatc gacccttatc tagcggatgt
    16561 caatgtgcat ccaactaagc aagaggtgcg gatttccaag gaaaaagaac tgatgactct
    16621 ggtttcagaa gctattgcaa atagtctcaa ggaacaaacc ttgattccag atgccttgga
    16681 aaatcttgcc aaatcgactg tgcgcaatcg tgagaaggtg gagcaaacta ttctcccact
    16741 caaagaaaat acgctctact atgagaaaac tgagccgtca agacctagtc aaactgaagt
    16801 agctgattat caggtagaat tgactgatga agggcaggat ttgaccctgt ttgccaagga
    16861 aaccttggac cgattgacca agccagcaaa actgcatttt gcagagagaa agcctgctaa
    16921 ctacgaccag ctagaccatc cagagttaga tcttgctagc atcgataagg cttatgacaa
    16981 actggagcga gaagaagcat ccagcttccc agagttggag tttttcggac aaatgcacgg
    17041 gacttatctc tttgcccaag ggcgagatgg actttacatc atagatcagc acgctgctca
    17101 ggaacgggtc aagtacgagg agtaccgtga aagcattggc aatgttgacc aaagccagca
    17161 gcaactccta gtgccctata tctttgaatt tcctgcggat gatgccctgc gtctcaagga
    17221 aagaatgcct ctcttagagg aagtgggcgt ctttctagca gagtacggag aaaatcaatt
    17281 tattctacgt gaacatccta tttggatggc agaagaagag attgaatcag gcatctatga
    17341 gatgtgcgac atgctccttt tgaccaagga agtttctatc aagaaatacc gagcagagct
    17401 ggctatcatg atgtcttgca agcgatctat caaggccaat catcgtattg atgatcattc
    17461 agctagacaa ctcctctatc agctttctca atgtgacaat ccctataact gtcctcacgg
    17521 acgtcctgtt ttggtgcatt ttaccaagtc ggatatggaa aagatgttcc gacgtattca
    17581 ggaaaatcac accagtctcc gtgagttggg gaaatattaa aagtataaaa aagtctggga
    17641 aaaattttca aaatcaaaaa aacgcataaa atcaggtgtt caaaaacctt gattttatgc
    17701 gttttatcat ggaaatagtt acttcatttt ttcctaattc ttttcgaaac tctttttaaa
    17761 cgacgtcagt tttatcagta atctcaaaac agtgttttga gctaattttg ccagttttgt
    17821 ctgtaacatc gaagttgtgt tttaccactc tgcgactggt ttcctagttt gctctatgat
    17881 tttcacagag tattaaattg cgattttgcc aagtttcttt attcgtctaa aagtagagtc
    17941 tgttctatgc gtctaatgta cgaattaggt tgaccatttc aatagctcct tgtgcacact
    18001 cagaaccctt atttcctgct ttagtgccag ctcgttctat ggcttgttca attgtatctg
    18061 tcgttagcac accaaacata acaggaattt cgctatttaa actgatttgg gcgattccct
    18121 tagatacctc gctacataca taatcataat gacttgtatt ccctctaatg acagctccca
    18181 agcagataat tgcatcatat tttttacttt ttgccatttt tgatgcaatc agtggtattt
    18241 caaaagctcc tggaacccag gctacctcta tatctttctc gtttacattc tctcttttga
    18301 gattatctag tgctccagat aataattttg aagttataaa ttcattaaat ctcgctacaa
    18361 caatacctat tttaatattg tttgctacta aattaccttc ataagtgttc atttattttt
    18421 cctccatatt taaaatgtga cccattcgat ttttctttgt ttctaaataa aaactatcgt
    18481 aaggattggc ttctatttcg attgatattc tactggaaat ggtaattcca tatttttcta
    18541 actgttcaac cttgtcagga ttatttgtca gtaaatgaag tgactgaagt cccagatctt
    18601 taagcatttg tgctccaata tgatattctc ttaaatcacc ttcaaagcct aatgcaagat
    18661 tggcatcaag cgtatccatg ccttgatctt gtaaatgata ggcttttaat ttattgataa
    18721 gtccaattcc tcgtccctcc tgtcgcaagt aaagtaagac acccgaacca ttctcaacaa
    18781 tcattttcat agctttatcg aattgctgtc cacaatcgca acgtaaggag cctaaaacat
    18841 cccctgttaa acattcggag tggacccgac ataatacatt ggcttcatcc tctatgtttc
    18901 ccataataag agcaagatga tgttccccat ttagtttatc tatatagcta attgctttga
    18961 aattaccgta tctagtaggc atattgacag ttgaaactcg ttctaccagc tgatcatata
    19021 cttttctata ttcttgtaat tctttgatgg taattagtgg aatgttgtgt ttcttcgaga
    19081 actgaattaa atcatctgtt ctcatcattt tgccatcatg attcattatt tcacaacata
    19141 ggccacactc ttttagtcca gctaatttta ataaatcaac agttgcttct gtgtgtccac
    19201 ttctttctag aacaccacct ttttttgcaa ttaaaggaaa catgtgtcct ggcctgcgaa
    19261 aatcagaggg tgttatatct tcagctacac acatacgtgc ggtcagtcct ctttcctcgg
    19321 cagaaatacc tgtggtcgtt tctttataat caattgaaac tgtaaaagca gtcttatgat
    19381 tatctgtatt gttttcaacc ataggtgaaa gcattaattg attagctaaa ctttcgctca
    19441 taggcataca aattaatcct ttggcataag tagccataaa attaacattt tctgttgtag
    19501 ctgcttgtgc agaacaaatt aagtctcctt cattttctct atccttgtcg tctataacaa
    19561 gaacaagtcg tcccttctgc aatgcttcta atgcttcttg tatttttcga tattccattg
    19621 actgattatc ctttctgcta aaatccattt tgatataata gttccttaga tatttctgat
    19681 tttggagagt tatccatcag tttttgcaca tatttaccta agatatcatt ttcaagattt
    19741 actgtactcc cgacttgttt actcttaaga atggtttgtt ccaaggtatg agggataaca
    19801 gatactgaaa agtttacttt ggagacttta gcgacagtca gactaatgcc gtcaattgta
    19861 atagatcctt tttcaactat taaatctaaa atttcttttt gtgtgttgat ttgataccat
    19921 acagcattat catctttttt tattgacgag atttttcctg taccatcaat gtgtcctgta
    19981 acgacgtgac ccccaagtcg accgttgaca gataaggctc tttctagatt cacctcactt
    20041 ccatgtttta atagagtaag agctgttcga ctccatgttt cattcattac atcaactgta
    20101 aaggattgat gattgaaatg agtaactgta agacagatac catttactgc tatactatcg
    20161 cctaaatgga tatccgttaa tatttttgag gctttaattg atagtttaca attacgagag
    20221 tctttctgta ttctttcaac ttttccgatt tcttcaatta ttcctgtgaa catggataaa
    20281 tcacttcact ttctatgaga tagtcatttc ctatttgaga aaatgcataa ggtttcaatc
    20341 taatagcgtc atttggcaaa gaaatacctt cacctccgac aggaaacttg gcactacctc
    20401 caaaaatttt tggtgcaata tatattttca gctcatcaac aatttgttgt tccaaagcac
    20461 tccaattcat tagactgccc ccttctagaa ctaggctatc aatctgcatg tttcctagat
    20521 gttgcattaa actcgataag tctatatgat tgcctttttt ctttatggaa agtatttcac
    20581 agccatgatt ttgatatagc ttcattttat ttttgtcttc agaggaagtg gcaatgtaag
    20641 ttttaatatc atttgctgtt tttacgattt tagaggtaag aggagttcgt aaatgtgtat
    20701 cgcatatgat acggatagga tttttccctt cctccaatct acatgtcagc aaaggatcgt
    20761 cttgaataac agtattgact cccaccataa ttgcactaac atggtgtcgt aactgctgca
    20821 catgctttct tgcttcttct tcagtaatcc atttggattg atttgtttta gtggctattt
    20881 ttccatccat tgacattgca tatttcataa aaacataggg tacatgctgg gtaatatact
    20941 ttctaaaact ttttattaag ttaagacact cattttctaa aattccaaca gtaacttgaa
    21001 gattattttc ctcaagtatc tttactcctt ttccagatac aataggatta cagtctaggc
    21061 ttccaatgac tactcttgta ataccactat cgattatagc atctatacag ggaggtgttt
    21121 tcccgaagtg acaacagggt tcaagtgtta cataaagcgt cgctccgaca ggggattctc
    21181 tacagttttt aagagcattt ctctcagcat gtgggccacc aaaaaactca tgataacctt
    21241 gtccgataat gtgattatct tttacaataa ctgcgccgac cataggattg ggattgacgt
    21301 aaccagcccc tttttgtgcc agttttattg ctaatttcat atattttgaa tcgctcatct
    21361 cactacctcc aaaaaaatat gccttgaata ggggactact caaggcatac aaaagaaaac
    21421 ttatgcgatt aacaaaaatg ctctgaaatg acaagtaatc atttcagagc acgcaaaaag
    21481 cacaaatata cttttatctt ctttcatcca gactatactg tcggctttgg aatttcacca
    21541 aatcatgcct ttcggctcgt gggctatacc accggtaggg aatttcaccc tgccctgaag
    21601 atagttattc aattacagat gattatagta cttaattttg aatatgtcaa cagataaata
    21661 ccgattgttt ttgatatact gtatttgtga taatcgattc tcgctcctcg gataaagaaa
    21721 atatgatata ctagataaac gaaataagag agaaggaata ctatgtacgc atatttaaaa
    21781 ggaatcatta ccaaaattac tgccaaatac attgttcttg aaaccaatgg tattggttat
    21841 atcctgcatg tggccaatcc ttatgcctat tcaggtcagg ttaatcagga ggctcagatt
    21901 tatgtgcatc aggttgtgcg tgaggacgcc catttgcttt atggatttcg ctcagaggat
    21961 gagaaaaagc tctttcttag tctgatttcg gtctctggga ttggtcctgt atcagctctt
    22021 gctattatcg ctgctgatga caatgctggc ttggttcaag ccattgaaac caagaacatc
    22081 acctacttga ccaagttccc taaaattggc aagaaaacag cccagcagat ggtgctggac
    22141 ttggaaggca aggtagtagt tgcaggagat gaccttcctg ccaaggtcgc agtgcaagca
    22201 agtgctgaaa accaagaatt ggaagaagct atggaagcca tgttggctct gggctacaag
    22261 gcaacagagc tcaagaaaat caagaaattc tttgaaggaa cgacagatac agctgagaac
    22321 tatatcaagt cggcccttaa aatgttggtc aaataggagc agagaatgac aaaacgttgt
    22381 tcgtgggtca agatgaccaa cccgctctac atcgcctatc atgatgagga gtggggccag
    22441 cccctccatg atgaccaagt attgtttgag ttgttgtgta tggaaaccta tcaggcaggc
    22501 ctgtcttggg aaacggtact caacaaacgc caagctttcc gagaagtctt tcatagctat
    22561 caaattcact cagtcgcaga gatgactgac actgaattgg aagccatgct ggagaatcca
    22621 gctatcattc gaaatagagc caagcttttt gctacacgcg ctaacgccca agtctttcta
    22681 cagttacagg cagagtacgg ctcttttgat gcctatcttt ggtcttttgt tgaggggaaa
    22741 actgtcgtta acgatgttcc tgattatcgc caagcgccag ctaaaacacc cttatctgag
    22801 aaattagcca aagatctcaa aaaacgaggc ttcaagttca caggcccagt cgccgtattg
    22861 tcttttctac aggctgcagg gctagttgat gaccacgaga atgattgtga gtggaaaggt
    22921 cttaaatgat gtctaacaaa aataagggaa ttctgatttt tgcgattctc tatacagtcc
    22981 tctttgtgtt tgatggcgtt aaattgctgg cttctttaat gccatctgtc attgcaaatt
    23041 atcttgttta tgtagtttta gctttatatg gctccttctt gttcaaggat agattgatcc
    23101 aacaatggaa ggagattaga aagactaaaa gaaaattctt ctttggcgtc ttaacaggat
    23161 ggctctttct cattctgatg actgttgtct ttgaatttgt atcagagatg ttgaagcagt
    23221 ttgtgagact agatggacaa ggtctaaatc agtctaatat tcaaagtacc tttcaagaac
    23281 aaccactact gatagctgtt tttgcttgtg tcattggacc tctggtagaa gaattatttt
    23341 tccgtcaggt cttattgcat tacttgcagg aacggttgcc aggtttacta agcattattc
    23401 tggtaggact tgtttttgct ttgactcata tgcacagttt ggctctatca gagtggattg
    23461 gtgcagttgg ttacttaggt ggaggccttg ccttttctat tatttatgtg aaagaaaaag
    23521 agaatatcta ctatccccta cttgttcaca tgttaagcaa cagcctctcc ttaatcattt
    23581 tagctatcag tatagtaaaa tgaaataaga acaggacaaa tcaatcagga cagtcaaatc
    23641 gatttctaac aatgttttag aagtagaggt gtactattct agtttcaata cactgtaaca
    23701 tgtgatgaaa atgccagtaa tgataccgag aaaaaagctg agaaactttt cccagcttta
    23761 tttgttatag tcaaagcgaa tgacttgttc ctgtgcatct acatgagcat ggaccccaaa
    23821 gggtacaatt gctcttggag ttgcgtggcc gacattcaga ttatagacaa tcgggatatt
    23881 gctgtcaatg atatctaata gtgcctcttt atagtcgtca tggaaagttt catccatagg
    23941 ttttccgacc aagagtccat tgatgaccgc gaatatgcca gtgtccttta aagttagcaa
    24001 catctttttg aagtcttctg gcttaggctt ttcttcgctt gtttcgagca agaggatttt
    24061 cccttcccag tctgacaagt cagggaaaag tttgtatttt gggcagagtt ccgtgctatc
    24121 tgcgtatcga gagttgtcaa agatatcgta gagggattct aggcaaccac cgaggatttt
    24181 cccctcgaac tgagcacttc cttgcaacaa gtcaaaacct gtatttgtat gactgacacg
    24241 aggtgttccc agggccgtgg gactaaaatc agttcgttcc tcataccaaa cgtcactagg
    24301 gcggatttct gaaattcttc ccgtctcaat caattcttta aagtagtgaa ggctataggc
    24361 tagcatttct ttgtctaatt cacaaatgtc tgctaaaaag gattgaccat aaaaagtctt
    24421 gattcctaat ttatgcaaca tgaggtggtt catggttgta tccgagaagc caagaaaaat
    24481 tttttgcttg ataacctttt ggagttggtc attttcaaaa agataaggta gcaagcgata
    24541 ggtatcgtct ccaccgatgg cacataggat catgtcgatg ctatcatcag aaaaggcatg
    24601 aatcaaatcc tctgcacgag cttcaggatg gtccttgata aagtctaatc cttttaacga
    24661 atggggcaaa aagatgggat tgagtcccag atccttgaga cgttggatac ccaagtccac
    24721 ttcgtgtttg acaaaatcct ctccgataat gccactagat aaactaacaa taccaatagt
    24781 agaaaccata tctcatcctc ctagaaatag attgagccta ttttatcaca aaatataaga
    24841 gaaagctatg tgggatttca gaagaatact tttaatactc ttcgaaaatc tcttcaaacc
    24901 acgtcagttt tatctgcaac ctcaaagctg tgctttgagc aacctgcagc tagcttccta
    24961 gtttgctctt tgattttcat tgaatataac tcaaaaaagt aagtgaaaaa gcaaccgcac
    25021 ctgcagttgc ttttatcgtt ttcttattct tgatagcgtg ttggtcctgc acttgcacta
    25081 cggatattca agcgtttctt gagatagaag cgaagggcta ggagggctgc tccaataata
    25141 gctagtggca atggatccag tactgggtta aggctagctg gtaggaagct tgttgcaaag
    25201 aagacaagca accaaaggaa catagaagct aggataacta gtacagattt ccagaaaggt
    25261 ggacgttgac tgcgatccat atctggtcca tagtattggt aaacaaagta gtacatcaag
    25321 tagaaggcaa atccaccaac cagtccaact aatagaagag taatcaatcc atagccgaaa
    25381 gcttggtctg ccgcaaagaa ggttgtgagg gcgctgacaa gggcaaagag gctagtgatg
    25441 aaaagagctg agtccataat catcagtttt gggtcatcat tttcttttgg atgctctttt
    25501 tcgtactgct ctttgacagt gaagctatga gcccaatgag ttggtgcgcc gtatagggaa
    25561 cgggcagttg tacctttaga ttgctcctca aggatttggg gaatgacttc ctcaaaaata
    25621 gtctggattt cagcgtctgt tttcccatct ttgatgaatt gttgggtagc aatgtggaca
    25681 aactcttggt ttttcttagt taatttttgt agatcaattt gagacatagg aactcctctt
    25741 agaaccattt tttatggatg agatagagag tgagcgagac actcatagca aaggcgataa
    25801 agacgattaa ccagaaggca tttggctctc cgtttagggg gatttcatta tccttaaagt
    25861 tcatcccgta ggcagaaaag accatggttg ggatggacat gacgatggtc acaagggcca
    25921 aggttttcat gatgttgttc tggttgttag aaatgataga ggcaaaggtc tctgtcatag
    25981 aatgcaagac gtttccataa atatctgcca tctcgatggc ctgttgggtt tcaatcaggg
    26041 tgtcttcaag caggtcttcg tcctcaaggt atttcttgat attgctggtt gaactggtca
    26101 atttcttaat cacgcgctca tttgttttga gggaggcctt gaaatagacg atagtttttt
    26161 ccaattccat gagctcaatc aattcttcat tacgagttga ttgatgcagt tgactttcga
    26221 tttgttcact cttgcggtcg attgaacgaa gggctgttag gtaaagctct gcattgcgat
    26281 aaagaatttg aaagataaaa cgtgaacgca tgaaggtata gaaattacgc aatcgacggt
    26341 tgataaagac atcaaggaca ggtagtggtt ccaaacacgt agtgataatg gtttcctcag
    26401 tgatgataat accaagcggg atggttacgt agtaggtgcg gttatttctt tcctccgtga
    26461 ccggcacgtc tacgataatc agggtatact cgtcttcaat ggtaatacga gacatttctt
    26521 ccgcatcgag cggtgctcga aggtcggcaa tatcaatatc gaaggtgttg gcgatttcga
    26581 gtgattcatt ttgagtcgga ttgacgagat tgatccaagt acccggttca agcgtatcga
    26641 tctctttaaa ttcagttgtt gtagagagaa aaacttgttt catatccctt atcctttctc
    26701 atttttcaga ttttttcaca ctgtactatt atactacaaa atcggccttt tgggtaatag
    26761 aatctcactt tttttggtat aatggtaagc aataatggac tagaaagaac aaagatgcaa
    26821 gataaaattg tcattcatgg ggcgcgtgcc cataatttaa aaaatattga tgtggagatt
    26881 ccgcgagaca agttggttgt cgtgactggc ttgtcaggtt cagggaagtc cagtctggct
    26941 tttgataccc tctatgcgga gggacaacgt cgctatgtag agagtttgtc cgcctacgct
    27001 cgtcagttct tgggaaatat ggaaaaacca gatgtagatg ccattgatgg tctcagccca
    27061 gctatttcca tcgaccagaa aacgactagt aaaaatcctc gctcgacggt gggaactacg
    27121 actgaaatca atgactatct gcgtctcctc tacgcacgtg tggggacgcc ttactgtatc
    27181 aacggacatg gagctatcaa tgcttcttcg gtggagcaaa tcgttgataa ggttttggag
    27241 ttacctgaac gccagcgctt gcagatcttg gctcctgtca tccgcaagaa aaaaggccaa
    27301 cataagagtg ttatcgagaa ggttcagaaa gacgggtatg ttcgtgttcg tgtggatggg
    27361 gaagtctatg atgtgaccga agtgccagag ttgtctaaga gcaagcaaca caatatcgat
    27421 gtcgtggttg accgtattgt tatcaaggag ggcattcgta gtcgtctctt tgattccatt
    27481 gaggctgccc ttcgtattgc agaaggttat gtcattatcg acaccatgga cgattcggag
    27541 ttgctcttct ctgagcatta tgcctgtcca gtttgtggtt ttactgtccc agagttagaa
    27601 cctcgtctct tctctttcaa tgctcctttt ggctcttgta gtgagtgtga cggcttgggg
    27661 atcaagctgg aggtagatac tgatttggta gtgccagatg ccagcaaaac cttacgtgag
    27721 ggagcgctag caccttggaa tcctatctca tccaactact atccaaacat gttagagcag
    27781 gccatgaaag tctttggagt ggctatggat aagccttttg aggacctgtc agaagaagat
    27841 aagaacttga ttctctatgg gtcagatggt aaggaattcc atttccacta tgagaatgaa
    27901 tttggtggcg tgcgcgatat cgacattccg tttgagggag ttatcaataa tatcaaacgt
    27961 cgttaccatg aaaccaatag cgattacact cgcactcaga tgcgtctcta catgaatgag
    28021 ctgacctgcg gaacctgtca aggctatcgt ctcaatgacc aggccttgtc tgtccgtgtg
    28081 ggcggccagc aagggccaca tattggagaa atctcagacc tgtctatcgc tgaccacttg
    28141 gacttggtga gccagttaac tttgtctgaa aatgaagcca tcattgctcg tcccattctc
    28201 aaggaaatca aggatcgttt gaccttcctt aataatgtgg gtcttaacta tctaaccctg
    28261 tcacgttcag caggaaccct ttcaggtggg gaaagtcagc gcattcgttt ggcaacccag
    28321 attggttcca acctatcagg cgtcctctat atcctagacg agccgtcaat cggtcttcac
    28381 cagagggaca atgaccgcct gattgccagt ctgaaaaaga tgcgtgactt gggcaatact
    28441 cttatcgtgg tggaacacga cgaagatacc atgcgtgaag ctgattatct gattgacgtt
    28501 ggtcctggtg ccggtgtttt tggtggtgag attgttgcag caggtacacc taagcaagtg
    28561 gctcgcaaca gcaagtctat cacaggtcag tacttgtcag gcaaacgtgt catcccagta
    28621 ccagaagagc gccgtgtcgg aaatggtcgt tttattgaag tgacaggagc gcgtgagaac
    28681 aacttgcaaa atgtcacggc tcgctttcca ctaggaaaat ttatcgcagt gacaggtgtg
    28741 tcgggttcag ggaaatcgac tctaatcaac agcattctca aaaaagccat tgcccagaag
    28801 ctcaaccgta attcagacaa acctggtaag tttaagacta ttacagggat tgagcatgtc
    28861 gaccgtttga ttgatattga ccagagccct atcggacgga cgccgaggtc taacccagct
    28921 acctatacag gagtttttga cgatatacgt gacctttttg ctcagacaaa tgaagccaag
    28981 attcgaggct acaagaaggg gcgcttcagt ttcaacgtca agggaggtcg ctgtgaagct
    29041 tgctcaggtg acgggattat caagattgag atgcacttct tgccagatgt ttatgtggct
    29101 tgtgaagttt gccacggaac ccgctataac agtgaaaccc tagaagttca ctacaaggaa
    29161 aagaatattt cgcaggtctt ggatatgacg gtcaacgatg cggtagaatt tttccaacac
    29221 attccgaaaa ttcaacgcaa actccagacc atcaaggatg tagggctagg ctatgtgacc
    29281 ttgggacagc cagctaccac cctttctggg ggagaagccc aacgtatgaa gttagctagc
    29341 gaactccaca aacgctcgac aggaaaatct ttctacattc tggatgagcc gacgacaggg
    29401 cttcatacag aggacattgc tcgcctgctc aaggttttag ctcgctttgt agacgatggc
    29461 aatacagtcc tcgtcatcga gcacaatctg gatgttatca agacggcaga ccatatcatt
    29521 gacttgggac ctgagggcgg tgtcggtggt ggaaccatca tcgtaacagg aactccagaa
    29581 gaagtagctg ccaacgaagc cagctataca ggacactatt tgaaaggaaa gttacatcat
    29641 gaataaacgc gtacaagcat ttctagctaa aatgcaagaa aaagaactag atggtatcat
    29701 catcaacaat cttaaaaacg tctattattt gactggtttt tggggctcaa acggaacagt
    29761 ctttatcagt cgtgaccgtc aggtcttagt gacagactct cgctatatca tcgcagctaa
    29821 gcaagaaacc agtggttttg agattgtggc tgatcgtgat gaattggctg tcattgcagg
    29881 aattgttaag gacatgggct tgactcgtat cggttttgaa gatgagattt cagtgtctta
    29941 ttaccaccgt atgcaggcag cttttgcagg tttgaacttg cttccacaaa ctcagtttgt
    30001 ggaaggtctt cgtatgatta aggatgaggc agagattgca gcgattcgca aggcttgttc
    30061 tatctcagac caagctttcc gcgatgcgct tgactttatc aaaccaggaa aaactgaaat
    30121 tgagattgcc aacttccttg acttccgcat gcgtgagttg ggagcatctg gcttatcttt
    30181 tgatacgatc ctagctagcg gtatcaattc ttctaaaccc catgcccatc caatgcacaa
    30241 accagtggag ttgggagaag ccattaccat ggacttcggc tgtctctatg accactatgt
    30301 cagtgatatg acccggacta tctatctagg gcatgttagc gatgagcagg cagagattta
    30361 caatacggtt ctaaaagcta accaagcctt gattgaccaa gctaaggcag gcttaggttt
    30421 ccgtgacttt gacaaaatcc ctcgtgatat tatcattgag gcaggttatg gcgactactt
    30481 tactcacggc attggccacg gtattggtct ggatatccat gaggaaccct actttagcca
    30541 gacttctaca gaaactatta agacaggtat ggccttgacc gatgaaccag gtatctatat
    30601 cgaaggcaaa tatggcgttc gtatcgagga tgatatcctg attacagaga caggttgtga
    30661 attattgacc ctagctccaa aagagttgat agtcatttag ttgtttgtca agaaaaaagt
    30721 acgaaaatga cgaaaaaagt caaaaaaaat taaaaatagg tcgcaagtcg gatgtttttt
    30781 atggtataat agactaaact gatagtaaca tgtagcgaaa ggggtaggta catgattaaa
    30841 atttatacag tctcaagttg tactagctgt aaaaaagcaa aaacctggct caatgcccac
    30901 cagttaagtt ataaagaaca aaaccttggt aaagaaggaa ttacgagaga agaattactg
    30961 gatattctaa ccaaaacaga taacggaata gccagcatcg tttcgtctaa aaatcgctat
    31021 gccaaagccc ttggagtgga tattgaagat ttgagtgtca atgaagttct caatctgatt
    31081 atggaaacac cgagaatttt aaagagccca atccttgtag atgaaaaacg cctgcaagtt
    31141 ggctacaagg aagacgatat tcgtgccttc ctaccacgct ctgtccgtaa tgtagaaaat
    31201 gcagaagcac gtttacgtgc agctctataa acatcaaggc tgggagcaat tcccagtctt
    31261 attctatttt aatttcaaaa agaaagaaga aagaaatgaa aaaaatagtt cttgttagtc
    31321 tagctttcct ttttgtcctg gttggttgcg gacagaaaaa agaaactgga ccagctacaa
    31381 aaacagaaaa ggatacgctt cagtcggcat tgccagttat tgaaaatgcc gagaagaata
    31441 cagttgtaac caagactttg gtcttgccca agtcagatga tggtagccag caaactcaaa
    31501 ccattacata caaggacaag acttttttga gcttaacgat tcaacaaaaa cgtccagttt
    31561 ctgatgagtt gaagacttat attgaccaac atggagtgga ggaaactcaa aaagctcttc
    31621 ttgaagcgga ggagaaggat aagtctatca ttgaagctcg taaattggca ggtttcaaac
    31681 ttgaaacaaa actattgagc gcaacggaac ttcaaacaac gactagtttt gattttcaag
    31741 ttctggatgt caagaaggct tcccagttgg aacatctgaa gaatattggt ttggaaaatc
    31801 ttttgaaaaa tgaaccaagc aactatattt cagatagatt ggcaaatggc gcgacagaac
    31861 aatagaaaat ccaaataaat agactgcctg aattgtagaa ggtaaggaat tatgctataa
    31921 tggtactatt ctaaggaaag agggtgttag aatgggattt actgaagaaa cagtacgttt
    31981 taaattggac gattccaata aaaaagaaat tagcgaaact ttgacagatg tttatgcttc
    32041 gttgaacgat aagggttaca acccaattaa ccaaatcgta ggttacgtat tgagtggaga
    32101 ccctgcctac gttcctcgtt ataataatgc acgaaatcaa atccgtaagt atgagcgtga
    32161 tgaaatcgtt gaggaattgg ttcgttacta cctcaaagga caaggagtcg atctataacc
    32221 tatgagaatt atgggattgg acgtcggttc aaaaacggta ggggtggcga ttagcgatcc
    32281 gcttggtttt acagctcaag ggcttgaaat catccagata aatgaagaac aaggccaatt
    32341 tggttttgac cgcgttaagg aattggttga tacttacaag gtggaacgat ttgtagtggg
    32401 cttgcctaaa aacatgaaca atacaagtgg accgcgcgtg gaagctagtc aagcatacgg
    32461 agcaaagcta gaagagtttt ttggtttacc agtagactat caggatgaac gcttgacaac
    32521 agtggctgct gagcgcatgt tgattgaaca agcagatatc agtcgcaata agcgcaagaa
    32581 agtcattgat aagttagcag ctcagctgat tttacaaaat tatttagata gaaaatttta
    32641 atataaagga gaggctatgt cacacgatca taaccacgac cacgaagaac gtgaactaat
    32701 cacactagta gatgagcaag gaaatgaaac cttgtttgaa atccttttga caattgatgg
    32761 aaaagaagaa tttggtaaaa actatgttct tctagtacca gttaacgcag aagaagacga
    32821 agacggacaa gttgaaatcc aagcttactc attcattgaa aatgaagatg gaacagaagg
    32881 cgaattgcaa ccaatcccag aagactcaga agacgaatgg aacatgattg aagaagtctt
    32941 caacagcttt atggaggagt gatacagtct gggagactgt atcagcccaa ctccagaaat
    33001 ggggaagagt tggaacgtcc agtgaacatt tttaccccaa ctcttagaaa ttgagaagag
    33061 ttggaacatc tagtggatgt ttttagccca tattcacatt catagtagct agttattagc
    33121 taaccaggta agaggtcggg acgaaaatcc tggccttgtt tttattagta accatacttt
    33181 aatgcgataa ttgattggac ttttgtcaag gagatgtgta tgtttgaagt agaagaatgg
    33241 ctccatagtc ggattggttt gaattttcga tcaggtttgg gccgaatgca gcaagcggtg
    33301 gatttgttag gaaatcctga gcagtcttac cctattatcc acgtaacagg gactaatggg
    33361 aaaggatcta ccattgcttt tatgagggaa ttatttatgg ggcatggcaa aaaagttgcg
    33421 acctttacct cccctcatat cgtctctatc aatgaccgaa tctgcattaa tgggcaacct
    33481 atagcagacg cagactttat ccgtttggct gatcaggtca aggagatgga gaaaacgctt
    33541 ctgcaaactc ctgaccagtt gtcctttttt gaattgctga ccttggttgc ttttctttat
    33601 tttagggagc aagaggtgga tttggtttta ttagaagtgg gaattggtgg cttacttgac
    33661 acgaccaatg tggtaactgg agagcttgct gtcatcacct ccattgggct tgaccatcaa
    33721 gaaaccttgg gtgatagtct agaagcaatt gcagagcaga aagctggtat tttcaaggct
    33781 ggtaagaagg cagtgattgc gaaattgcat ccagaagcta ggcttgtctg tcagaaaaaa
    33841 gccgaatctt tagctgttaa cctttatcag gcaggtcaag attttttaat gctgaatggt
    33901 gatttttcaa gctctttact aaatctttca cagctgaaca taggcttaga aggagtctat
    33961 cagcaggaga atgcagcctt ggcgttgcaa acttttcttc tttttatggg agaaggaaag
    34021 gaagctgttg atgaacaggc tgtaagaaag gccttggaac agacccattg ggctggtcgc
    34081 ttggagcgta ttcgcccaca gatttacttg gatggtgctc ataacctccc tgccttgact
    34141 cgcttggttg agtttattaa agaaaaagag caggaaggtt atcgtcctca aatcctcttt
    34201 ggatccttga aacggaagga ttatcaaggg atgttgggtt atctgactga aaatttacct
    34261 caagtggaac tcaagatgac tggttttgac tatcaagggt ctttggacga aagggatgtg
    34321 acaggttacg atatagtttc ttcttaccga gaatttatca gcgattttga agaaagagca
    34381 gatgctcagg atttgctgtt cgttacaggg tctctctatt ttatctcaga agtacggggc
    34441 tacctgctgg accgtgagca gataaattga cccccttgtt tgaacttgtt atactaggga
    34501 aattgctggt tagagaaaat ttctctaaat tggtagcaga aaggaaattc atcatgaaat
    34561 taaaaagatt cacactttct cttgcttctc tagcaagttt tagtctctta gtagcttgtt
    34621 cacaaagagc tcaacaggtt caacagcctg ttgctcagca ggtccaacag cctgctcaac
    34681 agaataccaa tactgcaaat gcaggaggta accaaaatca agcggctcca gtacaaaacc
    34741 aacctgttgc tcaatcgacc gatattgatg ggacttatac tggtcaggat gacggagacc
    34801 gtatcacttt agtggtaact ggaacgactg gtacatggac tgagctcgaa tctgacgggg
    34861 atcagaaagt caaacaggtt acatttgatt cagcaaatca acgcatgatt attggcgatg
    34921 atgtcaaaat ttacactgta aacggtaatc aaatcgtcgt agatgatatg gatagagacc
    34981 catcggacca aatcgtttta actaaataag actatgcaag tagaaagggc tggatttttc
    35041 agccttttta cttttaccta gaaaataatc ataaatactt gccttctacc gaatacctgc
    35101 gttatactag tatcaattac ttgtttttag cattcaaact atcaaggagg ggatatgaaa
    35161 tataggaaat ttcaattatt gatgtccaag tatggcttta gtctttcgat tatgctattt
    35221 gaactttgtc ttgtttttgg tctctttctt tatttaggac gcatggctcc cattttatgg
    35281 attactgtcc tcattctact gagtatcatc acaatcattt cgatagtcaa ccgtaatacg
    35341 actcctgaga ataaggtaac ctggttgtta gtagcctttg tgccagtatt tggtcccttg
    35401 ctctatctga tgtttggtga aaggcgattg tccaaaaaag aaatcaaaca actgaagaag
    35461 ctaggctcta tgcattttca agaagcaaat agccagctac taaaagagaa attaaaagaa
    35521 agtgacaagg cagcttatgg agtcatcaag tccttattga gtatggatac caatgctgac
    35581 atctatgatc aaactgcctc tacatttttt cctaacggag aagctatgtg gaaaaagatg
    35641 gtagaagatc ttaaaaaggc tgagaaattt attttcttgg aatattacat tatagaagaa
    35701 ggtttgatgt ggaatcgcat actagatata ctagagcaaa aggtagctca gggtgtagag
    35761 gttaagatgc tctatgatga tatcggctgt atggctactt taacaggaga ttatgcacat
    35821 cgacttcgtc agctgggcat cgaggcccat aaattcaata aagttattcc tcgtttgaca
    35881 gtggcttata ataacagaga tcatagaaaa atattgattg ttgatggtca gatagcctat
    35941 actggtgggg tcaatctggc agatgagtac attaaccacg tcgagagatt tggttattgg
    36001 aaggatagtg gaattcgctt agacggacta gcagtaaaag ctctgacacg cttatttttg
    36061 accacttggt acattaatcg aggagaaatt agtgattttg atcaatatca tttagaaaat
    36121 cattctatcc cgagtgacgg tttaaccatt ccatacggaa gtggacccaa gccaattttt
    36181 cgagcgcagg tagggaaaaa agtttatcag agtttaatca atcaagcaac agaatcggtc
    36241 tatattacga caccttattt gattatagat tatgatttaa cagagacaat caaaaatgca
    36301 gctatgagag gggtcgatgt tcgaattatc accccttaca taccagataa gaagttcatt
    36361 cagttagtca cgagaggagc ttatcccgac cttctttctg ctggtgttcg gatttatgag
    36421 tatagtccag gttttattca tagtaagcag atgttggtag acgaagattt tgcggtggtg
    36481 gggacaatca atctcgacta ccggagcttg gtacaccatt atgaaaatgc agtcttactc
    36541 tataaaactc cttctataag ggaaatcgcc cgagattttc gaaatatatt tgcagattct
    36601 caggaagtct atcctcattc tatcaaaacg agctggtatc aaaagcttgt aaaagaaatc
    36661 gcccagctat tcgcccctat cttataagaa atctagaact taggatacaa accagaccta
    36721 tttttcttgt cttttacgaa tagaaagaaa gaggagggga attcatgcta actaaggaag
    36781 aagtgaatga tatgattgag ttcaaacaga cacatttaca ccgctttcgg gaaattgaaa
    36841 cctttgtgaa actatgcaaa aaatcactca aacagccatc gcaagctgac aatcctagga
    36901 ctttttgata tactaagaca gataaattga acaggagaaa cgatatgagt gtgtatggta
    36961 gagtagaaga agttcataag gagaatcgtg aacctctaga ataccaaatc gaacaagaat
    37021 cgcatcatcg tgaatcaagt cgtcttcctt tggtgaaaat tttactatgg agtacgcttg
    37081 taacggggat aactctagga gtaccgctat tactcgactt aatgagtgca caagaagtgc
    37141 aggattttta tgcaggttgg gcgcttcatc agacagggaa gatttacagc gactattatg
    37201 gaagtcaagg tttgctttat tatttgctga cttacgtgag tcagggcgga tttttctttg
    37261 ccatctttga gtggttagcc ttggtagcag gaggattttt cctttttaga tcagcggaca
    37321 ccttgacaga gcaaggagac caagctggac atctggtgac tattttttac atgctagtta
    37381 caggtcttgc ttttggtgga ggctatgcga ctcttttagc gcttcctttc ttattcgcag
    37441 cctttagttt agttgcggct tacctaagca atccaagcca tgataaggga tttgtacgga
    37501 ttgggctagc tttggcaggc ggatttttct ttgctccctt atcatcgctc ctgtttattg
    37561 ctgtagtgag tttaggcttg ttggtcttta accttgggca tagacgtttt gtgcatgggt
    37621 tttatcagtt tcttgcagtg gctttaggtt tttcacttgt cttttatcca actgcctact
    37681 atagtgctgc aacaggaagt tttggggatg cgattagtgg tattcgttat cctattgaca
    37741 gtattcgctt tgattttact tctaaaattt tagagaatat gtttttttat ggcttgttgt
    37801 cccttggttt gggatttgtg gtttgtatct ttttaggtct ctttcaatcc aaacccttta
    37861 aactatacgt catttcggtt cctgcaagtc ttgtggtaat tttaggtttg attttacttt
    37921 tcttttcaca agagcctctg cacgcttctt atttgatggt cgtcttccct gttttcctac
    37981 ttttattggt aaccaatatt aagagtcaac agagggggcg tagtgttaga agaagccgaa
    38041 gagaaacgcc agttagccta tggagtcgtt tcttcaaagg aaatctatat ctgctagttt
    38101 ttgggcttgt ctatcttttg tctgttcctt ttttgatgaa gtttgtcctt tatccggtac
    38161 cttatcaaga acgtaatcgt cttgctgatt tggtaaaaga ggagacaaat acggaagatg
    38221 ctatctatgc atgggatgat actgcgactc tttatcgtaa gagtgagcgc ttgtcgccat
    38281 cggcgatttt gtccccgttg cactatacag caactgagga aaatcgtaat aagttactta
    38341 atgacttgaa agaaaaacaa cctaaggtga ttgtggtaaa tgacaaggtg gtagtctggt
    38401 ctgaagtgga aacactctta aaagaaaatt accaacaagt aaagactgat tactcagagt
    38461 ttaaagtcta taaaattaaa taaccaaatc aatatcttgt gtatttttaa aaattttagg
    38521 atttttaaca caagatattg atttttcttt ttagagtggt ataatacttt ttagaaagaa
    38581 cattttagaa aagagcatgc gtatgattgc actagaagaa aaaattacaa ttttgccaac
    38641 tctcttcgtc gagaaacgag atgggagacg tgttgtattt gatgtggaca agattgacaa
    38701 ggctctccac aaggcggctg acaaggttat ggatgtgaca cccctggttg aaaaacgcct
    38761 caatgatctg actgagcgaa ttattacaga aattcatagt cgctttccac agggaattaa
    38821 gatttacgaa attcaaaata tcgtagaaca tgaactcctt gaagccaaag aatatgcgct
    38881 ggctgaggag tatattactt atcggacaca gagggatttt gagcgctcaa aagcgacgga
    38941 tatcaacttt agtattcata aacttctcaa caaagaccag acagttgtca atgaaaatgc
    39001 taataaagac agtgatgtct ttaacactca gcgtgatttg acagcaggga ttgttgggaa
    39061 atcaatcgga ctgcaaatgc ttcctaagca cgtagccaat gcccaccaaa agggggatat
    39121 ccactatcac gatttggact acagtcccta tacccctatg accaactgct gtttgattga
    39181 ttttaagggt atgttggaaa atggttttaa gattggaaat gcagaggtag agagtcccaa
    39241 gtctatccag actgcgacag cacagatttc tcaaatcatt gccaacgttg cttctagcca
    39301 gtacggtggc tgttcagctg accgtatcga tgaaattttg gcgccttatg cagagaagaa
    39361 ctatcaaaaa catctcaaag atgcagaaga gtgggtattg cctgaaaaac gggaagatta
    39421 cgcttggaag aaaacgcaaa aggacatcta cgatgccatg caatctcttg agtatgaaat
    39481 caatactctc tttacttcaa atggacaaac accttttact tcgctaggtt ttggtctggg
    39541 aaccagtcgt tttgaacgag aaattcaaaa agctatttta aacattcgca tcaagggtct
    39601 tggttcagaa caccgtacgg ctatctttcc taaacttatc tttacgctta aaagaggcct
    39661 caacttagag gaaggaactc ccaactatga catcaagcag ttggctctag agtgtgcaac
    39721 caagcggatg tatccagacg tcttgtctta tgataagatt gttgatttga caggttcttt
    39781 caaggtgcct atgggctgcc gttctttcct tcaagggtgg aaggatgaaa atggtgtaga
    39841 agtcaattca ggtcgcatga atctgggtgt tgtgacggtt aatctgcctc gtattgctct
    39901 tgagtctgaa ggtgatatga ataagttctg ggaaatcttc aacgagcgaa tgaatatcgc
    39961 agaagatgct cttgtttacc gtgtcgaacg cactaaagag gcgacaccag cgaatgctcc
    40021 tattctttat cagtacggtg cttttggcca tcgtctaggt aaagaagaaa gtgttgacca
    40081 gctctttaag aatcgtcgtg cgaccgtttc gctgggctat atcggcttgt atgaagtagc
    40141 gacagttttc tttggtaaca gctgggaaag taatccagat gctaaggaat tcacgctaga
    40201 catcattcac gatatgaaac gccgtgtaga agagtggtca gaccaatatg gctaccattt
    40261 ctctatctac tcaacaccat ccgaaagtct gacagaccgt ttctgccgac tagatataga
    40321 caagtttggc tctattcctg atatcacaga caaggaatac tacaccaact ctttccacta
    40381 cgatgttcgt aaaaatccaa caccgtttga aaaattggac tttgagaaag tctatccgga
    40441 agcaggtgcg tcaggtggtt tcatccatta ttgtgagtat ccagtccttc agcaaaatcc
    40501 aaaggccttg gaagctgtct gggattatgc ttatgaccgt gtaggctatc taggcaccaa
    40561 tactccgatt gaccgttgct acaagtgtga ctttgaaggg gattttgaac caactgagag
    40621 agggtttgct tgtccaaact gtggcaatag cgaccctaaa acagtagatg tggtgaagcg
    40681 aacttgtggc tacctaggta atcctcaagc aagaccgatg gtcaacgggc gtcacaagga
    40741 aatcgctgcg cgtgtcaaac atatgaatgg ttcaacgatt aaaatagctg ggcatcaagt
    40801 aacaaattag aaagaaatga aatgggaaaa tatcaactag acgataaggg gcgcgcacaa
    40861 gtgacccgtt atcacgagaa acactctaaa ggtggagctg gtaagaaaga acgcttgctt
    40921 agcttcagag aacaattttt aaacaagaac aagaaaaaat aaaagtgaga gccagctctc
    40981 gcttttctca tagtgggagg taaggatgga attacgcaga ccaagattag cggataagaa
    41041 agctgtttta gatatgatga cagagtttga aaaatttcag tcgcctcacg acggcggttt
    41101 ctgggataca gagaactttg tgtatgaaga ctggttagaa agcaatcagg aacaggaaat
    41161 gggaattaat ctgcctgaag gatgggttcc tgcaattcag ttagtggctt tttctgagaa
    41221 aggtcaagca gttggatttc ttaatctccg gttgcgcctc agtaactttc tactagaaga
    41281 aggtgggcac attggctact ccatccgtcc atctgaaaga ggcaagggtt atgcaaaaga
    41341 gactctccgt cagggcttgc aagttgctaa ggaaaagaac atcaagaaag ctctggtgac
    41401 ctgtagcgtg aataatcctg ctagcagagc agtcattcta gcaaatggtg gaatatttga
    41461 ggatgctcgc aatggagtcg agcgttattg gatagaggta gcgaatgaat aatccaaaac
    41521 cacaagaatg gaaaagcgag gaacttagtc aaggtcgtat cattgactac aaggccttta
    41581 actttgttga tggcgaaggc gtgcgtaact ctctctatgt agcaggctgt atgtttcact
    41641 gcgagggatg ttataatgtt gcgacttggt cttttaatgc tggcattccc tatacagcag
    41701 aattagaaga gcagatcatg gcagaccttg cccaacccta tgttcaaggc ttgactttgc
    41761 tgggagggga gccttttctc aatactggca ttctcttgcc tctagttaaa cgcatccgaa
    41821 aggaattgcc agacaaggac atttggtcct ggacgggcta cacttgggaa gaaatgatgt
    41881 tggaaactcc agataaactg gaactcttat cattgattga cattcttgtc gatggacgat
    41941 acgatcgaac taagagaaat ctcatgctcc agtttcgagg ttcgtccaac caacgaatta
    42001 tcgatgtgca aaaatcgctc aaaagtgggc aagtagtgat ttgggacaag ctcaatgacg
    42061 gaaaagaaag ctatgaacag gtgaagagag aatgaagaaa aaagacttag tagaccaact
    42121 agtctcagag atcgagacgg ggaaagtcag gacactggga atatacggtc atggagcttc
    42181 aggtaaatca acctttgcac aggaattgta ccaagcttta gattctacta cagtaaattt
    42241 gctagaaaca gatccctata tcacctccgg acgctatttg gtagtaccca aggacgcgcc
    42301 gaatcaaaag gtgacagcca gtctgccagt ggcgcatgaa ctggagagtt tgcagagaga
    42361 tatccttgcc ttgcaggcgg gtatggatgt cttgacaatt gaagaacctt ggaaggctag
    42421 tgaggtcttg tctggagcca aaccaatttt gattgtcgaa gggatgtctg ttggctttct
    42481 acccaaggaa ctctttgaaa aaaccatctg tttctacacg gatgaggaga ccgaattaaa
    42541 gcgacgcctt gctagagata cgactgtgag aaatcgcgat gcatccttta tattggctag
    42601 ccatcagatg agacgggagc agtatctgcg atactataaa gaaactgagt ctaaggcgga
    42661 tatcttagtg gaccaatcag aagataaatt tgatgtcaag aggacttaac ttatgtatag
    42721 aagaaatata gaagaaaatc cctaatttta gaaagaaaaa gtaggaaaac agtttcatcc
    42781 caaaaaaacg aaaaaaccta acaaatccct tgcaatcgca ggggatttgt gttattctat
    42841 tatggtgctg taaattacag ccttagtttt gatgcaagag gttgcgacac gctcggttgc
    42901 attgccacgc aacaccgcgt cggttttctt gtggagctag cctattatct taaatagacg
    42961 aaaaggagaa aaagatggca aacaaaaaaa tccgtatccg tttgaaagct tacgaacacc
    43021 gtacgcttga cacagcggct gcaaaaatcg tagaatcagc tactcgtaca ggtgcacaag
    43081 ttgcgggtcc aatcccactt ccaactgaac gtagcctcta cacaatcatt cgtgcgactc
    43141 acaaatacaa agactctcgc gaacaatttg aaatgcgtac acacaaacgt ttgatcgata
    43201 tcgttaaccc aactcaaaaa acagttgatg ccttgatgaa attggatctt ccaagtggtg
    43261 taaacgtaga aatcaaactt taatctaaaa tataagagag cagaggctgg tgtttcaatc
    43321 taattgaaca cgggctaaac ttggtgtgaa aaagataaac ttcctcgcgt ctgctagaca
    43381 ctgtgtcagt ttcctatttt cacgttgagt ttgacgccct ttgtatctta gacttgagca
    43441 taaaaaacgc tcgttaaaaa ctttttgaat aaaaatatag aaaaggaact attttctcat
    43501 gacaaaagga atcttaggga aaaaagtggg aatgactcaa atcttcactg aagctggcga
    43561 attgatccct gtaacagtta ttgaagcaac tccaaacgtt gttcttcaag ttaaaactgt
    43621 tgaaacagac ggatacaacg ctatccaagt tggtttcgat gacaaacgcg aagtattgag
    43681 caacaaacct gctaaaggac atgtagcgaa agctaacacg gctcctaagc gcttcattcg
    43741 tgaattcaaa aacgttgaag gcttggaagt tggtgctgaa attacagttg aaacattcgc
    43801 agctggagac gttgttgacg taacgggtac ttctaaaggt aaaggtttcc aaggtgttat
    43861 caaacgccac ggacaatcac gtggaccaat ggctcacggt tctcgttacc accgtcgtcc
    43921 aggttctatg gggcctgttg cacctaaccg cgtattcaaa ggtaaaaacc ttgcaggacg
    43981 tatgggtggc gaccgcgtaa caattcaaaa ccttgaagtt gtacaagttg ttccagaaaa
    44041 gaacgttatc cttatcaaag gtaacgtacc aggtgctaag aaatctctta tcactatcaa
    44101 atcagcagtt aaagctggta aataataaag aaaggggaaa tcagtcacaa tggcaaacgt
    44161 aacattattt gaccaaactg gtaaagaagc tggccaagtt gttcttagcg atgcagtatt
    44221 tggtatcgaa ccaaatgaat cagttgtgtt tgatgtaatc atcagccaac gcgcaagcct
    44281 tcgtcaagga acacacgctg ttaaaaaccg ctctgcagta tcaggtggtg gacgcaaacc
    44341 atggcgtcaa aaaggaactg gacgtgctcg tcaaggttct atccgctcac cacaatggcg
    44401 tggtggtggt gttgtcttcg gaccaactcc acgttcatac ggctacaaac ttccacaaaa
    44461 agttcgtcgc ctagctctta aatcagttta ctctgaaaaa gttgctgaaa acaaattcgt
    44521 agctgtagac gctctttcat ttacagctcc aaaaactgct gaatttgcaa aagttcttgc
    44581 agcattgagc atcgattcta aagttcttgt tatccttgaa gaaggaaatg aattcgcagc
    44641 tctttcagct cgtaaccttc caaacgtgaa agttgcaact gctacaactg caagtgttct
    44701 tgacatcgca aatagcgaca aacttcttgt cacacaagca gctatctcta aaatcgagga
    44761 ggttcttgca taatgaattt gtatgatgtt atcaaaaaac ctgtcatcac tgaaagctca
    44821 atggctcaac ttgaagcagg aaaatatgta tttgaagttg acactcgtgc acacaaactt
    44881 ttgatcaagc aagctgttga agctgctttc gaaggtgtta aagttgccaa tgttaacaca
    44941 atcaacgtaa aaccaaaagc taaacgtgtt ggacgttaca ctggttttac taacaaaact
    45001 aaaaaagcta tcatcacact tacagctgat tcaaaagcaa tcgagttgtt tgctgctgaa
    45061 gctgaataat ctaaggagga aatatcgtgg gaattcgtgt ttataaacca acaacaaacg
    45121 gtcgccgtaa tatgacttct ttggatttcg ctgaaatcac aacaagcact cctgaaaaat
    45181 cattgcttgt tgcattgaag agcaaggctg gtcgtaacaa caacggtcgt atcacagttc
    45241 gtcaccaagg tggtggacac aaacgtttct accgtttggt tgacttcaaa cgtaacaaag
    45301 acaacgttga agcagttgtt aaaacaatcg agtacgatcc aaaccgttct gcaaacatcg
    45361 ctcttgtaca ctacactgat ggtgtgaaag catacatcat cgctccaaaa ggtcttgaag
    45421 taggtcaacg tatcgtttca ggtccagaag cagatatcaa agtcggaaac gctcttccac
    45481 ttgctaacat cccagttggt actttgattc acaacatcga gttgaaacca ggtcgtggtg
    45541 gtgaattggt acgtgctgct ggtgcctctg ctcaagtatt gggttctgaa ggtaaatacg
    45601 ttcttgttcg tcttcaatca ggtgaagttc gtatgattct tggaacttgc cgtgctacag
    45661 ttggtgttgt cggaaacgaa caacatggac ttgtaaacct tggtaaagca ggacgtagcc
    45721 gttggaaagg tatccgccca acagttcgtg gttctgtaat gaaccctaac gatcacccac
    45781 acggtggtgg tgaaggtaag gcaccagttg gtcgtaaagc accatctact ccatggggca
    45841 aacctgctct tggtcttaaa actcgtaaca agaaagcgaa atctgacaaa cttatcgttc
    45901 gtcgtcgcaa cgagaaataa tattaaacta gtcgcttaag caactagtaa atccgccagc
    45961 tcggtagcgc tccataggag tgcaagccgc tgtggtacaa catttaaagg agaaaatata
    46021 aaaatgggac gcagtcttaa aaaaggacct ttcgtcgatg agcatttgat gaaaaaagtt
    46081 gaagctcaag ctaacgacga aaagaaaaaa gttattaaaa cttggtcacg tcgatcaacg
    46141 atcttcccaa gtttcattgg ttacactatt gcagtttatg acggacgtaa acacgtacct
    46201 gtttacatcc aagaagacat ggtaggccac aaacttggtg aatttgcacc aactcgtact
    46261 tacaaaggtc acgctgcaga cgacaagaaa acacgtagaa aataaggaga acataaatgg
    46321 cagaaattac ttcagctaaa gcaatggctc gtacagtacg tgtttcacct cgtaaatcac
    46381 gtcttgttct tgataacatc cgtggtaaaa gcgtagccga tgcaatcgca atcttgacat
    46441 tcactccaaa caaagctgct gaaatcatct tgaaagtttt gaactcagct gtagctaacg
    46501 ctgaaaacaa ctttggtttg gataaagcta acttggtagt atctgaagca ttcgcaaacg
    46561 aaggaccaac tatgaaacgt ttccgtccac gtgcgaaagg ttcagcttca ccaatcaaca
    46621 aacgtacagc tcacatcact gtagctgttg cagaaaaata aggaggtaaa atcgtgggtc
    46681 aaaaagtaca tccaattggt atgcgtgtcg gcatcatccg tgattgggat gccaaatggt
    46741 atgctgaaaa agaatacgcg gattaccttc atgaagatct tgcaatccgt aaattcgttc
    46801 aaaaagaact tgctgacgca gcagtttcaa ctattgaaat cgaacgcgca gtaaacaaag
    46861 ttaacgtttc acttcacact gctaaaccag gtatggttat cggtaaaggt ggtgctaacg
    46921 ttgatgcact ccgtgcaaaa cttaacaaat tgactggaaa acaagtacac atcaacatca
    46981 tcgaaatcaa acaacctgat ttggatgctc accttgtagg tgaaggaatt gctcgtcaat
    47041 tggagcaacg tgttgctttc cgtcgtgcac aaaaacaagc aatccaacgt gcaatgcgtg
    47101 ctggagctaa aggaatcaaa actcaagtat caggtcgttt gaacggtgca gatatcgccc
    47161 gtgctgaagg atactctgaa ggaactgttc cgcttcacac acttcgtgca gatatcgatt
    47221 acgcttggga agaagcagat actacatacg gtaaacttgg tgttaaagta tggatctacc
    47281 gtggtgaagt tcttccagct cgtaaaaaca ctaaaggagg taaataacca atgttagtac
    47341 ctaaacgtgt taaacaccgt cgtgagttcc gtggaaaaat gcgcggtgaa gcaaaaggtg
    47401 gaaaagaagt agcattcggt gaatacggtc ttcaagctac aactagccac tggatcacta
    47461 accgccaaat cgaagctgct cgtatcgcca tgactcgtta catgaaacgt ggtggtaaag
    47521 tttggattaa aatcttccca cacaaatcat acactgctaa agctatcggt gtgcgtatgg
    47581 gatctggtaa aggggcacct gaaggttggg tagcaccagt taaacgtggt aaagtgatgt
    47641 tcgaaatcgc tggtgtatct gaagagattg cacgtgaagc gcttcgactt gctagccaca
    47701 aattgccagt taaatgtaaa ttcgtaaaac gtgaagcaga ataaggagaa ggcatgaaac
    47761 ttaatgaagt aaaagaattt gttaaagaac ttcgtggtct ttctcaagaa gaactcgcga
    47821 agcgcgaaaa cgaattgaaa aaagaattgt ttgaacttcg tttccaagct gctactggtc
    47881 aattggaaca aacagctcgc ttgaaagaag ttaaaaaaca aatcgctcgt atcaaaacag
    47941 ttcaatctga agcgaaataa tagactaggg aaggagaaat ttcaatggaa cgcaataatc
    48001 gtaaagttct tgttggacgt gttgtatctg acaaaatgga caagacaatc acagttgtag
    48061 ttgaaacaaa acgtaaccac ccagtctatg gtaaacgtat taactactct aaaaaataca
    48121 aagctcatga tgaaaacaat gttgccaaag aaggcgatat cgtacgtatc atggaaactc
    48181 gcccgctttc agctacaaaa cgtttccgtc ttgtagaagt tgttgaagaa gcggtcatca
    48241 tctaatcaaa cctgaaagga gaaaactgaa atgattcaaa cagaaactcg tttgaaagtc
    48301 gcagacaaca gcggtgctcg cgaaatcttg actatcaaag ttcttggtgg ttcaggacgt
    48361 aaatttgcaa acatcggtga tgttatcgtg gcatctgtaa aacaagctac tcctggtggt
    48421 gcggttaaaa aaggtgacgt tgttaaagca gttatcgttc gtactaaatc aggtgctcgt
    48481 cgtgctgatg gttcatacat caaatttgac gaaaacgcag cagttatcat ccgtgaagac
    48541 aaaactcctc gcggaacacg tatctttggc ccagttgcac gtgaattgcg tgaaggtggc
    48601 ttcatgaaga tcgtgtcact tgctccagaa gtactttaat ttttaggaac aaactagtcc
    48661 cctagcttca agctagggtg cccttatggg cgtaagaaaa atcaaggaga aacctaatgt
    48721 ttgtaaaaaa aggcgacaaa gttcgcgtaa tcgctggtaa agataaggga acagaagctg
    48781 ttgtccttac tgcccttcca aaagtaaaca aagttatcgt tgaaggtgtt aacattgtta
    48841 agaaacacca acgtccaact aacgagcttc ctcaaggtgg tatcatcgag aaagaagcag
    48901 ctatccacgt atcaaatgtt caagttttgg acaaaaatgg tgtagctggt cgtgttggtt
    48961 acaaatttgt agacggtaaa aaagttcgct acaacaaaaa atcaggcgaa gtgcttgatt
    49021 aatcacgaag gaaaggagaa gtataatggc aaatcgttta aaagaaaaat atcttaatga
    49081 agtagttcct gctttgacag aacaattcaa ctactcatca gtgatggctg tgcctaaagt
    49141 agataagatt gttttgaaca tgggtgttgg tgaagctgta tcaaacgcta aaagccttga
    49201 aaaagctgct gaagaattgg cacttatctc aggtcaaaaa ccacttatca ctaaagctaa
    49261 aaaatcaatc gccggcttcc gtcttcgtga aggtgttgcg atcggtgcaa aagttaccct
    49321 tcgtggtgaa cgtatgtacg aattcttgga taaattggta tcagtttcac ttccgcgtgt
    49381 acgtgacttc cacggtgttc caacaaaatc atttgatgga cgcgggaact acacacttgg
    49441 tgtgaaagaa caattaatct tcccagaaat caacttcgat gacgttgaca aaactcgtgg
    49501 tcttgacatc gttatcgtaa caactgctaa cactgacgaa gagtcacgtg cattgcttac
    49561 aggccttgga atgccttttg caaaataata taggaggtaa atctaatggc taaaaaatca
    49621 atggtagcta gagaggctaa acgccaaaaa attgttgacc gttatgctga aaaacgtgct
    49681 gcattaaagg cggcagggga ctacgaaggt ttatctaaat tacctcgcaa cgcctcaccg
    49741 actcgtttac ataatcgttg tagagttacg gggcgcccac attcagttta ccgcaaattt
    49801 ggtctgagtc gtatcgcttt tcgcgaactt gcgcataaag gtcaaattcc tggtgtaaca
    49861 aaagcatctt ggtaatttaa gatatcaaga gtgtcaaaac tccaagtaaa aataggaaac
    49921 ttgacgaaga aactaaagtt tctaggaaag tttatctttt tcacacagag tttagcccgg
    49981 gttcaattgg gcttgccaat ttgaacacga gctacagctt tggcaaaaaa gaccaatttg
    50041 ctttggagca ttgcttctgc attaaattgt ctatttttgc tcgtgctgtt acgctcttta
    50101 tatcatgtat taactagcaa gtgcaacttg caaactacta gtaagaggag aaaaacaaaa
    50161 tggttatgac tgacccaatc gcagacttcc taactcgtat tcgtaatgct aaccaagcta
    50221 aacacgaagt acttgaagta cctgcatcaa acatcaaaaa agggattgct gaaatcctta
    50281 aacgcgaagg ttttgtaaaa aacgttgaaa tcattgaaga tgacaaacaa ggcgtcatcc
    50341 gtgtatttct taaatacgga ccaaatggtg agaaagttat cactaacttg aaacgtgttt
    50401 ctaaaccagg acttcgtgtc tacaaaaaac gtgaagacct tccaaaagtt cttaacggac
    50461 ttggaattgc catcctttca acttctgaag gtttgcttac tgataaagaa gcacgccaaa
    50521 agaatgttgg tggtgaggtt atcgcttacg tttggtaaaa tcaagataca aagctcgtaa
    50581 agaacaaagc aaaattagga agttggagaa gtttgtttac aaacaagcca acttatctat
    50641 tttgcacagt tcttagagcg tgttcagttc agctcttgaa ctaaataagt atctgaaccc
    50701 cgtgaaaact ggccgttctg gcctgacaat ttaacaggag aaaataaaca tgtcacgtat
    50761 tggtaataaa gttatcgtgt tgcctgctgg tgttgaactc gctaacaatg acaacgttgt
    50821 aactgtaaaa ggacctaaag gagaacttac tcgtgagttc tcaaaagata ttgaaatccg
    50881 tgtggaaggt actgaaataa ctcttcaccg tccaaacgat tcaaaagaaa tgaaaactat
    50941 ccacggaact actcgtgccc ttttgaacaa catggttgtt ggtgtatcag aaggattcaa
    51001 gaaagaactt gaaatgcgtg gggttggtta ccgtgcacag cttcaaggat ctaaacttgt
    51061 tttggctgtt ggtaaatctc atccagacga agttgaagct ccagaaggaa ttacttttga
    51121 acttccaaac ccaacaacaa tcgttgttag cggaatttca aaagaagtag ttggtcaaac
    51181 agctgcttac gtacgtagcc ttcgttcacc agaaccatat aaaggtaaag gtatccgtta
    51241 cgttggtgaa ttcgttcgcc gtaaagaagg taaaacaggt aaataatgtt gagtggttga
    51301 tcatcaacca ccaacctatt ttccaacttt gtgcatagca cacgatttaa aactaaagag
    51361 gtgaaaactg tgatttcaaa accagataaa aacaaactcc gccaaaaacg ccaccgtcgc
    51421 gttcgcggaa aactctctgg aactgctgat cgcccacgtt tgaacgtatt ccgttctaat
    51481 acaggcatct acgctcaagt gattgatgac gtagcgggtg taacgctcgc aagtgcttca
    51541 actcttgata aagaagtttc aaaaggaact aaaactgaac aagccgttgc tgtcggtaaa
    51601 ctcgttgcag aacgtgcaaa cgctaaaggt atttcagaag tggtgttcga ccgcggtgga
    51661 tatctatatc acggacgtgt gaaagctttg gctgatgcag ctcgtgaaaa cggattgaaa
    51721 ttctaatagg aggacactag aaaatggcat ttaaagacaa tgcagttgaa ttagaagaac
    51781 gcgtagttgc tgtcaaccgt gttacaaaag ttgttaaagg tggacgtcgt cttcgtttcg
    51841 cagctcttgt tgttgttggt gaccacaatg gtcgcgtagg atttggtact ggtaaagctc
    51901 aagaagttcc agaagcaatc cgtaaagcag tagatgatgc taagaaaaac ttgatcgaag
    51961 ttcctatggt tggaacaaca atcccacacg aagttctttc agaattcggt ggagctaaag
    52021 tattgttgaa acctgctgta gaaggttctg gagttgccgc tggtggtgca gttcgtgccg
    52081 ttgtggaatt ggcaggtgtg gcagatatta catctaaatc acttggttct aacactccaa
    52141 tcaacattgt tcgtgcaact gttgaaggtt tgaaacaatt gaaacgcgct gaagaaattg
    52201 ctgcccttcg tggtatttca gtttctgatt tggcataaga aaggggataa aatggctcaa
    52261 attaaaatta ctttgactaa gtctccaatc ggacgcattc catcacaacg taaaactgtt
    52321 gtagcacttg gacttggcaa attgaacagc tctgttatta aagaagataa cgctgctatc
    52381 cgtggtatga tcacagcagt atctcactta gtaacagttg aagaagtaaa ctaatgaagt
    52441 tttaggggat gtgcactgta ccatccccta aaactagata tagtcatcta tgatgacatc
    52501 gtataggcga gttgatgggg gagacaacct tttctccctt atcggcgcta gcattttaca
    52561 aaagaggaga aaataaaaat gaaacttcat gaattgaaac ctgcagaagg ttctcgtaaa
    52621 gtacgtaacc gcgttggtcg tggtacttca tcaggtaacg gtaaaacatc tggtcgtggt
    52681 caaaaaggtc aaaaagctcg tagcggtggc ggagttcgcc ttggttttga aggtggacaa
    52741 actccattgt tccgtcgtct tccaaaacgt ggattcacta acatcaacgc taaagaatac
    52801 gcaattgtga accttgacca attgaacgtc tttgaagatg gtgctgaagt aactccagtt
    52861 gttcttatcg aagcaggaat tgttaaagct gaaaagtcag gtattaaaat tcttggtaac
    52921 ggtgagttga ctaagaaatt gactgtgaaa gcagctaaat tctctaaatc agttgaagaa
    52981 gctatcactg ctaaaggtgg ttcagtagaa gtcatctaag agaggtgacc tatgtttttt
    53041 aaattattaa gagaagctct taaagtcaag caggttcgat caaaaatttt atttacaatt
    53101 tttatcgttt tggtctttcg tatcggaact agcattacag ttcctggtgt gaatgccaat
    53161 agcttgaatg ctttaagtgg attatccttc ttaaacatgt tgagcttggt gtcggggaat
    53221 gccctaaaaa acttttcgat ttttgcccta ggagttagtc cctatatcac cgcttctatt
    53281 gttgtccaac tcttgcaaat ggatatttta cccaagtttg tagagtgggg taaacaaggg
    53341 gaagtaggtc gaagaaaatt gaatcaagct actcgttata ttgctctagt tctcgctttt
    53401 gtgcaatcta tcgggattac agctggtttt aataccttgg ctggagctca attgattaaa
    53461 actgctttaa ctccacaagt ttttctgacg attggtatca tcttaacagc tggtagtatg
    53521 attgtcactt ggttgggtga gcaaattaca gataagggat acggaaacgg tgtttccatg
    53581 attatctttg ccgggattgt ttcctcaatt ccagagatga ttcagggcat ctatgtggac
    53641 tactttgtga acgtcccaag tagccgtatc acttcatcta tcattttcgt aatcattttg
    53701 attattactg tattgttgat tatttacttt acaacttatg ttcaacaagc agaatacaaa
    53761 attccaatcc aatatactaa ggttgcacaa ggtgctccat ctagctctta ccttccgtta
    53821 aaggtaaacc ctgctggagt tatccctgtt atctttgcca gttcgattac tgcagcgcct
    53881 gcggctattc ttcagttttt gagtgccaca ggtcatgatt gggcttgggt aagggtagca
    53941 caagagatgt tggcaactac ttctccaact ggtattgcca tgtatgcttt gttgattatt
    54001 ctctttacat tcttctatac gtttgtacag attaatcctg aaaaagcagc agagagccta
    54061 caaaagagtg gtgcctatat ccatggagtt cgtcctggta aaggtacaga agaatatatg
    54121 tctaaacttc ttcgtcgtct tgcaactgtt ggttccctct tccttggtgt gatttccatt
    54181 ttaccgattg cagctaaaga tgtatttggt ctttctgatg ttgttgcctt tggtggaaca
    54241 agtctcttga tcattatctc tacaggtatc gaaggaatca agcaattgga aggttaccta
    54301 ttgaaacgta agtatgttgg tttcatggac agaacagaat aaaagtattt actgaatcag
    54361 taaatactga gggagtggag gtttaaactc tgacatttgt aagagttgaa tctcccctct
    54421 tctattttgt ttttaaatag gggtgaaaag actttttgct tctatttaaa aataaaataa
    54481 ggagatcaaa tcatgaatct tttgattatg ggcttacctg gtgcaggtaa gggaactcaa
    54541 gcagcaaaaa tcgtagaaca attccatgtt gcacatatct caacaggtga tatgttccgc
    54601 gctgcaatgg caaatcaaac tgaaatgggt gttcttgcta agtcatatat tgacaagggt
    54661 gaattggttc ctgacgaagt tacaaatgga atcgtaaaag aacgcctttc acaagatgat
    54721 attaaagaaa caggattctt attggatggt tacccacgta caattgaaca agctcatgcc
    54781 ttggacaaaa cattggctga acttggcatt gaactagaag gtattatcaa tattgaagtg
    54841 aaccctgaca gcctcttgga acgtttgagt ggccgtatca tccaccgcgt aactggagaa
    54901 actttccaca aggtctttaa cccaccagtt gactataaag aagaagatta ctaccaacgt
    54961 gaagatgata agcctgagac agtaaaacgt cgtttggatg ttaatattgc tcaaggagaa
    55021 ccaatcattg ctcactaccg tgccaaaggt ttggttcatg acatcgaagg taatcaagat
    55081 atcaatgatg tcttctcaga tattgaaaaa gtattgacaa atttgaaata aagcgttttt
    55141 cgcacttgca aaaatccgct acaaatgtta tactgagata gtctgactta taattgttgt
    55201 ctctgtgtct agaggcatcg aatcgaaatt tatggaggtg cttttgcgtg gcaaaagacg
    55261 atgtgattga agttgaaggc aaagtagttg atacaatgcc gaatgcaatg tttacggttg
    55321 aacttgaaaa tggacatcag attttagcaa cagtttctgg taaaattcgt aaaaactata
    55381 ttcgtatttt agcgggagat cgtgttactg tcgaaatgag tccatatgac ttgacacgtg
    55441 gacgtatcac ttaccgcttt aaataatcga aaaacttgga gggataagaa atgaaagtaa
    55501 gaccatcggt caaaccaatt tgcgaatact gtaaagttat tcgtcgtaat ggtcgtgtta
    55561 tggtaatttg cccagcaaat ccaaaacaca aacaacgtca aggataagat agaaaggaga
    55621 aaacatggct cgtattgctg gagttgatat tccaaatgac aaacgcgtag taatctcatt
    55681 gacttatgtt tatggtatcg gacttgcaac atctaagaaa attttggctg ctgctggaat
    55741 ctcagaagat gttcgtgtac gtgatcttac atcagatcaa gaagatgcta tccgtcgtga
    55801 agtggatgca atcaaagttg aaggtgacct tcgtcgtgaa gtaaacttga acatcaaacg
    55861 tttgatggaa atcggttcat accgtggtat ccgtcaccgt cgtggacttc ctgtccgtgg
    55921 acaaaacact aaaaacaacg cccgcactcg taaaggtaaa gctgttgcga ttgctggtaa
    55981 gaaaaaataa tataggaggt aaaagtcttg gctaaaccaa cacgtaaacg tcgtgtgaaa
    56041 aagaatatcg aatctggtat tgctcatatt cacgctacat ttaataacac tattgttatg
    56101 attactgatg tgcatggtaa tgcaattgct tggtcatcag ctggtgctct tggtttcaaa
    56161 ggttctcgta aatctacacc attcgctgct caaatggctt ctgaagctgc tgctaaatct
    56221 gcacaagaac acggtcttaa atcagttgaa gttactgtaa aaggtccagg ttctggtcgt
    56281 gagtcagcta ttcgtgcgct tgctgccgct ggtcttgaag taacagcaat tcgtgatgtg
    56341 actccagtgc cacacaatgg tgctcgtcct ccaaaacgtc gccgtgtata atcatcgcat
    56401 tacactgctt ttcgtttaag agggagtaac taaatgatcg agtttgaaaa accaaatata
    56461 acaaaaattg atgaaaataa agattatggc aagtttgtaa tcgaaccact tgaacgtggc
    56521 tacggtacaa ctcttggtaa ctctcttcgt cgtgtacttc tagcttctct accaggagca
    56581 gctgtgacat ctatcaacat tgatggtgtg ttacatgagt ttgacacagt tccaggtgtt
    56641 cgtgaagacg tgatgcaaat cattctgaac attaaaggaa ttgcagtgaa atcgtacgtt
    56701 gaagacgaaa aaatcatcga actggatgtt gaaggtcctg ctgaagtaac agctggtgac
    56761 attttgacag atagcgatat tgaaattgta aatccagatc attatctctt tacaatcggt
    56821 gaaggttctt ctctaaaagc gactatgact gttaacagtg gtcgtggata tgtacctgct
    56881 gatgaaaata aaaaggataa tgcaccagtt ggaacacttg ctgtagattc tatttataca
    56941 ccagttacaa aagtcaacta tcaagtggaa cctgctcgtg taggtagcaa tgatggtttc
    57001 gacaaattaa cccttgaaat cttgacaaat ggaacaatta ttccagaaga tgctttaggg
    57061 ctttcagcac gtattttgac agaacatctt gatttgttta caaatcttac tgagattgct
    57121 aagtcaactg aagtgatgaa agaagctgat actgaatctg acgaccgtat tttagatcgt
    57181 acgattgagg aactggactt gtctgtgcgt tcatacaact gtttaaaacg tgccggtatc
    57241 aatactgtgc atgatttgac agaaaaatct gaagcagaga tgatgaaagt acgaaatctt
    57301 ggacgcaaga gtttggaaga agtgaaactc aaactcattg atttgggtct tggattaaaa
    57361 gataaataaa ggaggaatac atggcttacc gtaaactagg acgcactagc tcacaacgta
    57421 aagcaatgct tcgcgatttg acaactgacc ttttgatcaa cgaatcaatt gtgacaactg
    57481 aagctcgtgc taaagaaatc cgtaaaactg ttgaaaaaat gattactcta ggtaaacgtg
    57541 gtgatttgca tgcacgtcgt caagcagctg ctttcgtacg taatgaaatc gcatctgaaa
    57601 actatgatga agcaactgat aagtacactt ctactacagc acttcaaaaa ttgttctcag
    57661 aaatcgcacc tcgttatgct gaacgtaacg gtggatacac tcgtatcctt aaaactgaac
    57721 cacgtcgtgg tgatgcagcg ccaatggcga tcatcgaatt agtataaaat catcaatttt
    57781 gttgagtgtt atgatgatgg agtcttgtgc tcttagtcta gctctggtct accgctagga
    57841 tttcggtcct agcgggaaca ctcatcataa gttgggatag tagacgcttg tttacgaaat
    57901 tgtttttttc ttaagaacaa cttcgtaagc aggcgttttt gagtattttc gttagaatta
    57961 tgctatacta tttgaaaaga atcctgttta atgttaaggt ttcttatttt aagaagaatt
    58021 ggagtttact tatgaaagcc attataactg ttgttggtaa agataaatct ggaattgttg
    58081 caggtgtttc tggtaaaatt gcagaattag gattgaatat tgacgatatc tctcaaactg
    58141 tattggatga atattttacg atgatggctg ttgtatctag tgatgaaaag caagatttta
    58201 cctatcttcg taatgaattt gaagcttttg ggcaaacttt gaatgtaaaa atcaatattc
    58261 agagtgcagc gattttcgaa gctatgtata atatctagga ggtcatcatg gatattagac
    58321 aagttactga aaccatcgcc atgattgagg agcaaaactt cgatattaga accattacca
    58381 tggggatttc tcttttggac tgtatcgatc caaatatcaa tcgtgctgcg gagaaaatct
    58441 atcaaaaaat tacgacaaag gcggctaatt tagtagctgt tggtgatgaa attgcggctg
    58501 agttgggaat tcctatcgtt aataagcgtg tatcggtgac acctatttct ctgattgggg
    58561 cagcgacaga tgcgacggac tacgtggttc tggcaaaagc gcttgataag gctgcgaaag
    58621 agattggtgt ggactttatt ggtggttttt ctgccttagt acaaaaaggt tatcaaaagg
    58681 gagatgagat tctcatcaat tccattcctc gcgctttggc tgagacggat aaggtctgct
    58741 cgtcagtcaa tatcggctca accaagtctg gtattaatat gacggctgtg gcagatatgg
    58801 gacgaattat caaggaaaca gcaaatcttt cagatatggg agtggccaag ttggttgtat
    58861 tcgctaatgc tgttgaggac aatccattta tggcgggtgc ctttcatggt gttggggaag
    58921 cagatgttat catcaatgtc ggagtttctg gtcctggtgt tgtgaaacgt gctttggaaa
    58981 aagttcgtgg acagagcttt gatgtagtag ccgaaacagt taagaaaact gcctttaaaa
    59041 tcactcgtat cggtcaattg gttggtcaaa tggccagtga gagactgggt gtggagtttg
    59101 gtattgtgga cttgagtttg gcaccaaccc ctgcggttgg agactctgtg gcacgtgtcc
    59161 ttgaggaaat ggggctagaa acagttggca cgcatggaac gacagctgcc ttggccctct
    59221 tgaacgacca agttaaaaag ggtggagtga tggcctgtaa ccaggtcggt ggtctatctg
    59281 gtgcctttat ccctgtttct gaggatgaag gaatgattgc tgcagtgcaa aatggctctc
    59341 ttaatttaga aaaactagaa gctatgacgg ctatctgttc tgttggattg gatatgattg
    59401 ccatcccaga agatacgcct gctgaaacta ttgcggctat gattgcggat gaagcagcaa
    59461 tcggtgttat caacatgaaa acaacagctg ttcgtatcat tcccaaagga agagaaggcg
    59521 atatgattga gtttggtggt ctattaggaa ctgcacccgt tatgaaggtt aatggggctt
    59581 cgtctgtcga cttcatctct cgcggtggac aaatcccagc accaattcat agttttaaaa
    59641 attaagaaaa taggagaaat tttaagttct atttaagatt agatgtgtat actataatca
    59701 ttaaataaag acctcctaat attatttgaa acagataaca ctgaattagt ttgaatttga
    59761 ttttcatcta atatctttat ttaatgaact cctaaacttt ttcataataa tctccttcaa
    59821 aagtcgcctg tatgggtggc ttttatttta tcattcatga tataatagaa gcaaacggag
    59881 gacggaaaat ggtaaaagta cgattgtatt tggtacgtca tggcaagacc atgtttaaca
    59941 cgattggtcg cgcgcaaggt tggagcgata ctcccttaac tgctgaaggt gaacgaggga
    60001 ttcaagagtt aggaatcggt ttgcgagaat ctgatctaca gtttgagcgc gcttattcga
    60061 gtgattctgg tcgtaccatt cagaccatgg gaattatact tgaagaactt ggcttgcagg
    60121 ggaaaatccc ttatcgcatg gacaagcgta tcagagaatg gtgtttcggt agttttgatg
    60181 gagcctatga tggcgatctt ttcatgggca ttattcctcg tatctttaat gtggaccacg
    60241 ttcaccaatt gtcttatgct gaactggctg agggcttggt agaggtcgat acagctggtt
    60301 gggctgaagg ctgggaaaaa ctcagtggcc gaatcaagga aggctttgaa atgattgcaa
    60361 aagaaatgga agatcaaggt ggaggtaacg cccttgttgt cagccatgga atgactattg
    60421 gaaccattgt ttatctgatt aatggcatgc atccgcatgg tctagataat ggtagcgtga
    60481 cgattcttga atatgaggac ggtcagttta gggttgaagt tgtcggtgac cgtagttacc
    60541 gagagctagg acgtgagaag atggaagaag gctctattta atcagtctag acttgcttgc
    60601 catgagctag ggatttgata agaatatcaa gataagaaaa aacagccgag ggtactcctt
    60661 tcggctgttt ttgatgtgga aaactaaagt gtaatgctat tgcttttaga gattttcata
    60721 aacaagagca aggaacctac tgttagaaca gtcaggatag ttgacaaggc tgcggctaca
    60781 ccgtaatttc ctctgagaac ctctgtataa atagctacag tcattgttct tgttttgaca
    60841 ttgtagagga ggatagaagt agagagtttt gaaatcattg tgacccaaga taagatggct
    60901 ccagaaatga taccagatag catcattgga gttgtaatct tagcaaaggt attgagacga
    60961 ctacttccta agctttcagc agcttcttca atacttggtg ctatttgttg taagctagca
    61021 acagatgagc gaatagtata aggtaatctt ctgacagata gagacataat caagatgaaa
    61081 gcagtccctg taatcataag aaatccactt ccaaatagac cagtattgaa ggaagaaatg
    61141 aaggcaatcc ctagaacggt tcctggtaca atataaggta ccatactgag gctgtcaatt
    61201 aagtttgtaa acaaattccg ttttctaacg gctaggtagg agataaatgt cgcaaataga
    61261 acaactagaa ctaaggcaat caaagggata cgaatggtat tgaaaatagc agatcccata
    61321 cgattgaaag ctaccttgta actgtttgga gaataacctt taacaaatac catacctgat
    61381 gtttttagga aagaggtata aattaagtag atttgaggta aaacagagat aaagataatt
    61441 ccgtagactg ttgcataaat ggcagccatt tttccttttg tagttttttt aggctcaatt
    61501 ggatggatca gattcatgct gaaactgtag cggtttgcaa tgtgtttttg gataaggaaa
    61561 attgccaagg caatgataat cgccataatt gcaaaagcag aatttcctcc aacctcgcta
    61621 ataaattggg tataaatcag gacagggaaa gtccgatatc cttcgccaat caacataggc
    61681 gttccaaagt ctgagaatgc tctcataaat acaagcaagg agctgctagt aaggttggaa
    61741 ctagaagagg taaaacaacc gttacgatag gtttaaatcc gaaggacccc atgctttcag
    61801 ctgcttcaag tagagaattg tcaatactgt tcattgttcc agcaacatat agaaatacca
    61861 gtgggaatag ttgcagtgta aagacaagta caattccttt gaatccataa atatcgatag
    61921 ctggaagatg aagggcattt gtcaaaaatt tagtgatgac cccatttcgt cccagcaaga
    61981 gaacccagga gtaggctcct acgaaaggag ctgacatgga agcaatgata atcaatattt
    62041 gtagaaattt cttccccttg aagtcataca tagagaagag ataagctaat agggttccta
    62101 caactaagga agtgacagta gcggtaatgg aaaccctgaa actgttgact agtgtctcag
    62161 agtagtaggc tttactaaag aaagtgacaa aattagctag tgagaattgt ccttcatgta
    62221 taagtgcttg cttgagcacg gtaacgatag gataaacgag aaagacaaga taggtaagaa
    62281 agatgaagaa agaggaagct gtccaaatat ttagtttttt acattccatg gttgactcct
    62341 tttatcaggt tttgggaacc atctgcagaa aagatgttta atttttgcgt attgattcgt
    62401 agacgaatac gattgccttt ttgtagttct tcttcaaaag ttgattcttc actaacttga
    62461 atttttgagg caaaacctgt ctcaatgaaa tactccgtat ttagtccaag atagacgcta
    62521 tcgctaatag ttccttcaat atctccagat tcatctttga taaactcttc gggacgaatg
    62581 cttacatgaa tagcttgctc ctcaacctga tcaagagctg gcattcgaag ggcatagcca
    62641 tctgaaaaga cgatataagc gccgtcgctc cgtttttcaa gattggcatg gataatattt
    62701 gtgcgtccga taaaggttgc cacaaactca ttagctggtt tatgatagag ttattttggt
    62761 cggccgattt gttggatcac cccatctttc ataacagcaa tttggtctga aatagccatg
    62821 gcttcttctt ggtcgtgggt tacataaaca gttgtaattc ccacttcgtg ttggatttct
    62881 cggatggctt gacgcatatc caagcgaagt ttggcctcca gattactaag tggctcgtcc
    62941 atgaggagaa cacttggatt aaccgctaag gcgcatgcca aggtgacacg ttgttgttgt
    63001 ccaccactga gtttatcggg ctttcgatcc gcatattgag caatttgcat gagttcaaga
    63061 tacttgttgg tctgttgaat caattcttct tttggaacct tcttttgctt aagaccaaaa
    63121 gcaacgttgt ctcggacagt caaatgtggg aaaatagcgt agttttggaa aaccatcccg
    63181 atattgcgtt tgctggattc catattattg atttttgtat catcgaagta aaattctcca
    63241 tctttgatac tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc acatcctgaa
    63301 ggtccaagaa gggtaaagag acttcctttt ggaattgtaa tgttcaaatt ctcaataaca
    63361 gggacatcgt ggtagatttt ttggcgttaa taattttgat ctcactcata gtgaaccttt
    63421 tttactgttt agattggata tctgtaaaga cttcgttgta tttcttaacg atatctgatt
    63481 tattcttgat gacataatca taatcttcag tgagtgtttt gattttgtca attggtttca
    63541 tgttttcgct tgttttagca tttttacgaa caggacggtt agtagtggtt gtaccaagtg
    63601 tatcttgtac ttcttgagag ataataaaat cgataaattt cttggcattt tccatatttt
    63661 tagatttttt aacgatagca gcactagcag gtaggaagac ggttccttct tttggataga
    63721 ctaccttaat gttagctccg tcatttaaga gcttaactgc tggatcttca taagagagac
    63781 caacagtcat ttctccatca gcgactgctt tatagacacc agatgaactt aaaccgattt
    63841 tatagtatat tgaaactaga atagtacaca tctgcttcta aaatattgtt agaaatcgat
    63901 ttgactgtcc tgattaactt gtcctgttct tatttcattt tactatacca tcaataagtg
    63961 tgaaaagatc ttttacataa gaccaagcct tatcatcttt gtaaccacct tgagcttgta
    64021 gcatatttgt taattgagca aaggcgctag aagagtttgc tgggtcagca gttgcgattt
    64081 ttccttttag ttcaggtttg agaagatcgt tatatccttc gatgttcatg cctttagtta
    64141 aatcagggtt gacgattaaa acactaccat ctagtgtata aggagtagag tagccagttg
    64201 tgttttgata ttctttgata acattatcat tttcttttga aatatacttt tcaaagagtt
    64261 ctccgtgggt agcatattgt gtataagaac caccaaagat aatatcagct acaggaactt
    64321 ctttttctga ctctagtttt ttgaaaagtt ctccagtacc agcttgaatc agttctattt
    64381 tgataccata tttttcttca aaggcaggaa tagttgctcc aattaagccc tctgagtttg
    64441 gtcaataaac gactagcgaa ccgccgtctc ctttatcaga tgaactgtca tcggcagatt
    64501 cattagaaga acaagcagca taatacatcc atttcttttt catgatggat acctccgttg
    64561 tgttatttaa gtttatttta aaacaatgta agcgttttta aaacatacaa ttctattcta
    64621 tagtgtattg aaaatagaat agtacacctc tacttctaaa acattgttag aaatcgattt
    64681 gactttcctg atagagatgt tcacatctta tttcaattca ctatattaga gtaaaattct
    64741 ctacaaaaag aagaatagcc tattttacta ttcttccgag taatttcaat tcctttgggg
    64801 aaatatggag atgcttttta aatactttgg caaaatattt atagtctgaa aatccaactt
    64861 ggtcagagat agcgcttaaa ggggagttgg gagattcagc catcttatct atagcttgtt
    64921 tcaggcgata ttgtaagata tattcattta gagtcatggg gaagtcttct ttgataacct
    64981 tatatagatg cttgttatct gcaaatatct agagcatttc aaggaaataa actagaaata
    65041 acaattaata tggtggttca gaaatacctt ttgataatca ataagatctt caggatgaag
    65101 tgcgttgact ccatccattt catatttccg atttaataaa cgatatttgt tttcaccaaa
    65161 ttgatgaaaa gggagtagtt gaacttggtc aatatttaat gagttaaata gagtagcgaa
    65221 tttttctgca tcctctaaac tattgttaaa attaggaata actgggattc ttaaaacgat
    65281 agttttattt tgagaaaaag cataatgaat gtttttaata atcatttgat taaaaacccc
    65341 agtcactttt ttatgtttta tagaattata atgttttagg tctgtgtaga taaaatccac
    65401 atattgaatt aaatcgataa atttttcatg atcaacaaag gcagtagttt caatggcagt
    65461 gtgtatgtga tgttctttag ctgattttaa gatggcttta gcaaattcaa actgagcaaa
    65521 tatttcacct cctgataaag ttaaacctcc accggattct tcgtaaaatt ctttgtcttt
    65581 taatacctct gtaataattt cttctacagt cttttcttca ccgactaagg tgaatttctc
    65641 tcgttgagca tctttcattt tttcaggttt cattctttga gattcaggat tagaacacca
    65701 tggacagcgc agaggacatc cttttaaaaa aacagttgta cgaatacccg ggccgtcatg
    65761 aattgaaaag tgttgaatat taaaaataat tcctttagat atttccataa gagttcctcc
    65821 tcttcataag tctatcctat cacaaaaacg aaagaaaaac aattacgaac gaaaggttaa
    65881 tttgttgttt tttgcttttt attttggtag aataaaacgg aggtgtaaaa tgaaaagatt
    65941 ggaacaaatt attaaattag tatcagaaca tgaaaagatc gacgttaata cattatcgga
    66001 aaaattaaat gtatcgaaag taacgattag aaaagattta gataaattag agtcaaaagg
    66061 tttattgcac agagagcatg gatatgctgt attaaatagt ggagatgact taaatgtacg
    66121 tttgtcaatt aactatgaaa ttaagagaaa aattgttcag gaagcagtaa aattggtgtc
    66181 agataatgaa acaataatga tagaatctgg atcgacctgt gctttacttg ctgaggaaat
    66241 ttgcaagcaa aaaagaaatg ttacgattgt aacaaattca ttttttatag caaattttgt
    66301 gagagcttat gattcatgtc gtattattgt tcttggtgga gagtttcaga aggattcaca
    66361 ggttactgtg ggacctttat taaaagaaat gatacagact tttcatgtgc atcaagcttt
    66421 tgttgggaca gatggttacg ataaagagat gggctttaca ggaaaagatt taatgcgcag
    66481 tgaggtagtt caatatattt cagcagcatc ggataaagtc attgtactaa ctgactcaag
    66541 taaatttgat aaaaggggta cagtaagaag atttgcttta agtcaagtct atgaagtaat
    66601 aacagacgaa aaactttcta aacaaaatat agctacatta gaaaatgctg ggataatggt
    66661 taaggtagtt tcgtaagagg ttaagtgtat gaatcaagat aggaataaac tgctctctaa
    66721 aattgcttat ctgtattata ttgaaaactt aaatcagtca caaatagcag caaaattagg
    66781 aatttataga acctctatta gtagaatgtt aacagaagca aggaatgcag gaattgttaa
    66841 aattgaaata gagaattttg ataccaatat gtttaagttg gaaaattatg taaaagaaaa
    66901 atatggtctg gaaagtttag aaattattcc aaatgaattt gatgatactc caacaatttt
    66961 atctgaaaga atttctcaag ttgcagcagg tgtccttagg aatctaattg atgataatat
    67021 gaaaattggc ttttcttggg ggaaaagttt aagtaattta gtagatttaa ttcacagtaa
    67081 aagtgtccga aatgttcact tctatcctct agcaggtggt cctagtcaca tacacgctaa
    67141 ataccatgtg aatacactga tttatgaaat gtctagaaaa tttcatggag agtgtacatt
    67201 tatgaatgca acgattgtgc aagaaaataa attgttagca gatggtattt tgcaatcaag
    67261 atattttgaa aatttgaaaa atagttggaa agatttagat atagctgtag tcggaattgg
    67321 tgattttagc aataaaggaa agcatcaatg gttagacatg cttacagagg atgactttaa
    67381 agaattgacc aaagttaaaa ctgtaggaga aatttgttgt cgattttttg attcaaaagg
    67441 taaagaagtc tatgaaaact tacaggaaag aacgatagca atctctttgg aagatttaaa
    67501 aaatattcct caaagtttag ctgttgctta cggtgatacg aaagtatctt cgattctttc
    67561 tgtcttgcgt gctaatttag taaatcattt gattacagat aaaaatacaa ttttaaaagt
    67621 tttggaagaa gatggtgatt tgacttttag agagattcta ggtgagtgaa aatgatagac
    67681 tgatcagttt atcgtttttt ctttttagtc gattgcacat ttgtgcttat ataaacaaaa
    67741 atagtttatc tgttgttttt ggattgacaa ctttattatg tagttgtatt ctatagttac
    67801 aaaagaaaat tttaaaattt caaatgaaaa aagcttttta catagtgaaa tgaggaggaa
    67861 tttatggaaa ttattgttcc agatcaaatt atcatgggtt taattttata tgctggcgat
    67921 gcgaaacaac atatttataa agcattagat tacataaaga acggtacatg tgaacgatgt
    67981 gaagaagaaa tccagttagc tgatgccgcc ttattagaag ctcataatct acaaacaaaa
    68041 ttcttggcac aggaagcgtc tggtacaaag acagaaatta cagctctctt tgttcattca
    68101 caagatcatc tcatgactag tatgacggag attaatttaa tcaaagaaat tattagtttg
    68161 agaaaagaac ttcataaaaa ataatactag agtattatca ttgttattaa catagaggag
    68221 gaaaacataa tggtgaagat tggtttgttt tgtgcagcag gtttttctac tggtatgctt
    68281 gtaaataata tgaaaattgc agcgcaagct agtggagttg aggcagaaat agaggcgttt
    68341 tctcagtcta aattagcgga ttatgcgcca aatatagatg ttgcactatt gggtccacaa
    68401 gttgcttata cattagataa atcaaaagaa atttgtgata agtgtgatgt tccgatagct
    68461 gttattccga tgatggacta tggtatgtta gatgggaaaa aagtattaga tttggcccta
    68521 tctttgatta gtgggtaaga aaaggagatt tattatgtca aagatggatg ttcagaaaat
    68581 cattgcaccg atgatgaagt ttgtgaatat gcgtggcatt atagctctaa aagatgggat
    68641 gttagcaatt ttgccattga cagtagttgg tagtttgttc ttgattatgg gacaattgcc
    68701 gttcgaagga ttaaataaga gcattgctag tgtttttgga gctaattgga cagagccgtt
    68761 tatgcaagta tattcaggaa cttttgctat tatgggtcta atttcttgtt tttcaattgc
    68821 ctattcttat gctaagaata gcggagtaga ggctttacca gctggagttc tatctgtatc
    68881 tgcattcttt attttgctaa gatcatctta tatccctaaa caaggtgagg cgattgggga
    68941 cgctattagt aaagtttggt ttggaggcca aggaattatc ggtgctatca ttataggttt
    69001 ggtagtagga agtatttata ccttctttat aaagagaaaa attgttatta agatgccaga
    69061 acaagttcca caagctattg cgaaacagtt tgaagcaatg attccagcat ttgtaatttt
    69121 cttatcttct atgattgtat atattttagc gaagtcattg actaatggcg gaacattcat
    69181 agaaatgatt tattctgcta ttcaagttcc gttgcaaggt ttaactggat ctttgtatgg
    69241 tgctattgga attgcattct ttatatcatt tttgtggtgg tttggtgttc atgggcaatc
    69301 ggtagtaaat ggagtagtga cagctctgct tttatctaat cttgatgcta ataaagctat
    69361 gttagcctct gctaatctat cattagaaaa tggtgcacat attgttactc aacaattttt
    69421 agattcattt ttaattctat caggttcagg gattacgttt ggtcttgtag ttgccatgct
    69481 ttttgcagca aaatcaaaac aataccaagc cttaggaaaa gttgcagctt ttccagcaat
    69541 atttaacgta aatgagccag ttgtatttgg atttccgatt gtcatgaatc cagttatgtt
    69601 tgtacctttc attcttgttc ctgtacttgc agctgtgata gtatatggag ctattgcaac
    69661 aggtttcatg cagccattct caggggtaac attgccttgg agtacaccag ctattctatc
    69721 aggatttttg gtgggtggat ggcaaggtgt tgtgactcag ttattagtat tggtgatatc
    69781 tacagtggtt tactttccat tctttaagat acaagatcgt ttagcttacc aaaatgaaat
    69841 caaacaatct tagaggtatt tgtgtgttac tgttaaactc acacatttgt gctaaaaatt
    69901 agagagttaa aatttttcta gttaaaagct tgaaaatttc tataaaaatc ggtattatat
    69961 tttcgaaaga aataaaaata ttttcgaaag aaaggtgctt acgatggtaa atacagaagt
    70021 agcaagaaca acaatcaaga cagaatattt tggcagcctt actgaaagga tgaacaaata
    70081 tcgagaagat gttttaaata aaaaacctta tattgatgct gagagagcag ttctagcaac
    70141 acgcgcctat gaacgataca aggaacaacc taatgtccta aaacgtgcat atatgctgaa
    70201 agaaattttg gaaaatatgt ctatctatat tgaagaagaa tctatgattg cgggaaatca
    70261 agcttcttcc aataaagatg ctcctatttt tccggaatat acgctagaat ttgttctcaa
    70321 tgagttggat ctttttgaaa agcgtgatgg agatgttttc tatattacag aagaaacaaa
    70381 agaacaactt agaagtattg ctccgttttg ggaaaataat aatttacgtg ctagagctgg
    70441 tgccttatta cctgaagaag tgtcagttta tatggaaaca ggattcttcg gtatggaagg
    70501 taagatgaat tctggagatg ctcacttagc agttaactat cagaaacttt tgcaatttgg
    70561 tttaagaggt tttgaagagc gggctcgtaa agcaaaagta gctctagatt taacagatcc
    70621 agcaagtatt gataaatatc atttttacga ctctatattt atcgtaatcg atgctattaa
    70681 agtatatgca aagcgctttg ttgctcttgc taaaagttta gccgaaaatg caaatcctaa
    70741 acgtaagaaa gaattacttg agattgcaga tatttgctct agagtcccat atgaaccggc
    70801 aactactttt gcagaagcta ttcaatcagt ttggtttatt caatgtattt tacaaattga
    70861 atctaatggc cactctcttt catatggccg ttttgatcaa tatatgtatc catatatgaa
    70921 gactgattta gaaagtggta aagaaacaga agatagcatt gttgaacgtc tgacaaatct
    70981 ttggattaag acaattacaa ttaataaggt tcgcagtcaa tcacatacat tttcttcagc
    71041 aggaagtcct ttatatcaaa atgttacaat tggtggacag actcgagata agaaggatgc
    71101 tgttaaccca ttatcttatt tggtcttaaa atcagttgca caaacccatc taccgcaacc
    71161 taatctaact gtacgttacc atgcaggttt agatgctcgt ttcatgaatg agtgtattga
    71221 agtgatgaaa cttggttttg gtatgcctgc atttaataat gatgagatta ttattccttc
    71281 ttttattgca aaaggagtat tggaagatga tgcttatgat tacagtgcca ttggatgtgt
    71341 tgaaacggca gttccaggga aatggggcta tcgttgcaca ggtatgagtt atatgaactt
    71401 ccctaaggtt ctacttatca cgatgaatga tggaattgat ccggcttcgg gtaaacggtt
    71461 tgcaccaagc tttggtcatt ttaaggatat gaagaacttt tctgaattag aaaatgcttg
    71521 ggataaaaca ctaagatatt tgacacgaat gagtgttatt gttgaaaatt ctattgattt
    71581 atcattggaa cgagaagttc ctgatattct atgttcagca ttgactgatg attgtattgg
    71641 tcgtggaaaa caccttaaag aaggtggagc agtatatgat tatatatcag gattgcaagt
    71701 tggaattgca aatttgtcgg attcattagc tgcaattaaa aaattggtgt ttgaggaaga
    71761 acgtataagc ccaagtcagc tttggcatgc actggaaaca gattatgccg gagaagaagg
    71821 taaggtcatt caagaaatgt tgattcatga tgcacctaag tatggtaatg atgatgatta
    71881 tgctgacaaa ttggttactg ctgcttatga catttatgtt gatgaaattg ctaaatatcc
    71941 taatacacgt tatggaagag gtccaattgg aggaattcgt tattcaggaa catcttctat
    72001 ctcagccaac gtagggcagg gacgtggaac attagcaact ccagatggac gcaacgcggg
    72061 tacaccgtta gcagagggtt gttcaccatc acataatatg gatcaacacg gccctacatc
    72121 tgttttaaaa tctgtttcaa aattaccaac agatgaaatc gtaggtgggg ttctcttaaa
    72181 tcagaaagta aatcctcaaa cgttagccaa agaagaagat aaattaaaac taattgcttt
    72241 gttacgaaca ttctttaatc gtttacatgg gtaccatatt caatacaatg ttgtttccag
    72301 agagacgctg attgacgctc agaaacatcc tgaaaaacac agagacttaa ttgttcgtgt
    72361 tgcaggatac tctgcattct tcaatgttct ttctaaggca acccaagatg acattatagg
    72421 acgtactgag catactttgt aaaataaaga ggttcttttt atggaattta tgcttgacac
    72481 attaaattta gatgagatta aaaagtggtc tgaaattttg ccgctagctg gggtaacttc
    72541 aaatcccact attgcaaaaa gagagggttc tattaatttt tttgaacgaa tcaaagatgt
    72601 aagagaattg attggctcta caccctctat tcatgttcag gtgatttctc aagattttga
    72661 aggcatctta aaggatgctc ataaaattcg aagacaagca ggagatgata tatttatcaa
    72721 agtacctgtt actccagctg gattacgtgc aataaaggcg ctaaaaaaag agggctacca
    72781 tatcactgca acagctattt atacagttat tcagggatta ttagctatcg aagcaggagc
    72841 ggattaccta gctccatatt ataatagaat ggaaaatctg aacattgatt caaattctgt
    72901 cattcgtcaa ttagctcttg ctattgatag acagaactct cctagtaaga ttttagctgc
    72961 atcctttaaa aatgtagcac aagtaaataa tgctttagct gcaggtgcgc atgctgttac
    73021 agcaggagca gatgtttttg aatcagcttt cgccatgcca tctatccaaa aggcggttga
    73081 tgatttttct gacgattggt ttgttactca aaatagtcgt tccatttaga tagagaggaa
    73141 atacatatga gaatttttgc tagtccttct agatatattc agggggaaaa tgccttgttt
    73201 gaaaatgcca aatcaatttt ggatttggga aattacccga ttctattatg cgatcagttg
    73261 gtttatgata ttgttggaaa acgatttgaa gattatctac ataggtatgg tttccatatt
    73321 gttctggcgc tatttaatgg tgaagcttct gacaatgaaa tcaatcgagt tgttgccttg
    73381 gctgagaaag aaaattgtga tagtattatc ggtcttggtg ggggaaagac gattgatagc
    73441 gcaaaagcta ttgcagattt gattgaaaag cctgttatta ttgctccaac aattgcatcg
    73501 accgacgcac ctgtatctgc tttatctgtt atttatacag atgaaggtgc atttgatcat
    73561 tatctatttt attctaaaaa tccagattta gttttggttg atacaaaagt tatttcacaa
    73621 gcccctaagc gtttattagc gtctggtatt gcagatggtt tagcaacttg ggttgaggcg
    73681 cgtgcggtta tgcaggcaaa tggaaaaact atgttgggac aacagcaaac attggctgga
    73741 gttgcaattg cgaagaaatg tgaagaaacg ctgtttgcag atggtttaca ggctatggca
    73801 gcttgtgaag ctaaagtggt gacaccagca ttagaaaata ttgttgaagc taatacttta
    73861 ttgagtggtc taggttttga aagtggagga ttagctgcgg cgcatgcaat tcataatggt
    73921 tttactgcat tgacaggtga cattcatcat ttaacacatg gtgaaaaagt agcttatgga
    73981 actttagtac aactattatt ggaaaataga cctaaagaag aacttgataa gtatattgag
    74041 ttttacaaaa aaattggtat gccaacaact ctaaaagaaa tgcatttgga tcaagttgga
    74101 tatgatgatt taataaaagt tggtaaacaa gcaactatgg agggtgagac aattcatcag
    74161 atgccgttta agatttcgcc ttcagatgtt gctcaagcta ttatcgctgt agatgcctat
    74221 gtaaattcaa aataaacaat aaggactact gttttccaaa tggtagtctt ttattgatcc
    74281 ctgtattgaa ttctatagaa gattgaaata ggatgagaac aaatcgattg ggaaagtaaa
    74341 attaatttct ataaatgttt tagcaattgt ttcgtactat tttagattca gtctactata
    74401 cgttcttcat aaatcaaaaa gcgacatagg tagtcggcta tttattgtga atacattaat
    74461 tagcattcca gttttatctt cggtctaaaa taagtatttt gtgctatacg agataagctt
    74521 cttgacttac tccttgattt actgcataac aatgggataa aaagtgggag atagagcaat
    74581 tcatagtcat caaaattaat gagatacagt atacagtttt tcctttaaac acatttcaaa
    74641 ttccctcaaa aatggtataa tagtaacatc acaaaattgg agagagagca tgagttttta
    74701 caatcataaa gaaattgagc ctaagtggca gggctactgg gcagaacatc atacatttaa
    74761 gacaggaaca gatgcatcaa aacctaagtt ttatgcgctt gatatgttcc cttatccgtc
    74821 tggagctggt ctgcacgtag gacacccaga aggttatact gcaaccgata tcctcagtcg
    74881 ttacaaacgt gcgcaaggct acaatgttct tcacccaatg ggttgggatg cttttggttt
    74941 gcctgcagag caatacgcta tggatactgg taatgaccca gcagaattta cagcggaaaa
    75001 cattgccaac ttcaaacgtc aaatcaatgc gcttggattt tcttatgact gggatcgtga
    75061 agtcaacaca acagatccaa actactacaa gtggactcaa tggattttca ccaagcttta
    75121 cgaaaaaggc ttggcctatg aagctgaagt gccagtaaac tgggttgagg aattgggaac
    75181 tgccattgcc aatgaagaag tgcttcctga cggaacttct gagcgtggag gctatccagt
    75241 tgtccgcaaa ccaatgcgcc aatggatgct caaaatcacg gcttacgcag agcgcttact
    75301 caatgactta gatgaacttg attggccaga gtctatcaag gacatgcaac gcaactggat
    75361 tggtaaatca actggtgcta atgtaacctt taaagttaag ggaacggaca aggaattcac
    75421 agtctttacc actcgtcctg atactctttt cggtgcgact ttcactgtct tggctcctga
    75481 acatgaatta gtagacgcta tcacaagttc agagcaagca gaggctgtag caaactataa
    75541 acatcaagct agcctcaaat ctgacttggc tcgtacagac cttgccaaag aaaaaactgg
    75601 tgtttggact ggtgcttatg ccatcaaccc tgtcaatggt aaagaaattc caatctggat
    75661 tgccgactat gttcttgcta gttacggaac aggtgccgtt atggccgttc cagctcacga
    75721 ccaacgtgac tgggaatttg ccaaacaatt tgaccttcca attgtagaag tgcttgaagg
    75781 tggaaatgta gcagaagctg cctatacaga ggatggtctt catgtcaatt cagacttcct
    75841 agatggactc aacaaagaag aagctattgc caagattgtg gcttggttgg aagaaaaagg
    75901 ctgtggacaa gagaaggtta cctaccgtct ccgcgactgg ctctttagcc gtcaacgtta
    75961 ctggggtgaa ccaattccta tcattcattg ggaagatggg acttcaacag ctgttcctga
    76021 aagtgaattg ccacttgtct tgcctgtaac caaggatatc cgcccttcag gtacagggga
    76081 aagtccattg gctaacttga cagattggct tgaagtgact cgtgcagatg gtgtcaaagg
    76141 tcgtcgtgaa accaacacta tgccacaatg ggcaggttca agctggtact acctccgcta
    76201 tattgaccca cacaatactg agaaattggc tgatgaggat cttctcaaac aatggttgcc
    76261 agtagatatc tacgtgggtg gtgcagagca tgctgttctt cacttgctct acgctcgttt
    76321 ctggcataaa ttcctctatg acctcggtgt tgttccaact aaggaaccat tccaaaaact
    76381 ctttaaccaa ggaatgattt tgggaacaag ctaccgtgac caccgtgggg ctcttgtggc
    76441 aaccgataag gttgaaaaac gtgacggttc tttcttccat gtggaaacag gagaggagtt
    76501 ggagcaagcg ccagccaaga tgtctaaatc tcttaagaat gttgtcaacc cagacgatgt
    76561 ggtggagcaa tacggtgccg atacccttcg tgtctatgaa atgtttatgg gaccacttga
    76621 tgcttcgatt gcttggtcag aagaaggtct ggaaggaagc cgtaaattcc ttgaccgtgt
    76681 ttaccgtttg attacaagta aagaaatcct tgcggaaaac aatggcgctc ttgacaaggt
    76741 ttacaacgaa actgttaaag ctgtcacaga gcaaattgat tccctcaaat tcaacacagc
    76801 cattgcccaa cttatggtct ttgtcaatgc ggctaacaag gaagacaagc tctatgttga
    76861 ctatgccaaa ggatttatcc aattgattgc cccatttgca cctcacttgg cagaagaact
    76921 ctggcaaact gttgctgcaa caggtgagtc aatctcttac gtgacttggc caacatggga
    76981 cgaaagtaaa ctggttgaag acgaaatcga aatcgttgtc caaatcaaag gtaaagtccg
    77041 tgccaaactc atggtcgcta aagacctatc acgtgaagaa ttgcaagaaa ttgctctagc
    77101 ggatgaaaaa gtcaaagcag aaattgacgg taaggaaatc gtgaaagtga ttgcggtacc
    77161 taacaaactc gttaatatcg tcgttaaata acgagtttat tagctctatc tgccaccttc
    77221 aatagtccac tggactattg aagccaacta aattggttaa tattgttgtg aaataagata
    77281 ggaatccttc agagtagaat ctgggggatt ttttgaatct tcttatgaaa gtatggtata
    77341 ctatgggcaa ctataaagtt tgaaaagtga aaaaaggaga aagctatgcc agtaaatgaa
    77401 tatggtcaaa tgattgggga gtcaatggaa ggttatacac caggtgaact gccttctatt
    77461 gatttcttag aagggcgtta tgctaggata gaggctcttt cagtggaaaa gcatgcggag
    77521 gatttgctag ctgtttatgg gcctgatacg cctcaggaga tgtggaccta cctttttcag
    77581 gagccagtag cagatatggg ggagctggtt agccttttac atcagatgtt ggctcgtaag
    77641 gaccgttttt actatgcaat catagacaag gcgactggta aggctttggg atctttttct
    77701 ctcatgcgca ttgaccagaa taaccgagta atagaagtgg gagcagtcac tttttctcca
    77761 gagctaaggg gtacacggat aggaactgaa gctcagtatc tcctagctcg ctatgttttt
    77821 gaggagctaa actatcgtcg ctacgagtgg aaatgcgatg ccttaaatct gccatccaga
    77881 cgagctgcgg agcgtttgag ctttatttat gaaggaacct tccgtcaggc agtggtttat
    77941 aagggacgta cgagagatac ggattggttg tctatgattg ataaggactg gcctcaagtc
    78001 aaagatcgtt tggaaacatg gttgcgtcct gaaaattttg ataaaaatgg acagcagtac
    78061 aagagcttga gagaacttta agaggtgttg agatgattac tattaaaaag caagaaattg
    78121 tcaagctaga ggatgtttta catctctatc aggctgtcgg ttggacaaat tatacccatc
    78181 aaccagagat gctggagcag gccttatctc attcattagt aatttatctg gcacttgatg
    78241 gtgatgctgt ggtgggcttg attcgtttgg ttggagatgg attctcatca gtattggttc
    78301 aggatttaat cgttttacca atctatcagc gtcaaggaat tggtagtgcc ttgatgaaag
    78361 aggctttaga ggattacaaa gatgcctatc aagtccagct ggtgacagaa gagacagaaa
    78421 gaaccttggg cttctatcgt tctatgggct ttgaaatctt atccacctat aattgtatag
    78481 ggatgacttg gatgaatcgt aaaaaataac aaaacttgtt ttttcttaag caaaatttaa
    78541 ggatggtcta gtattatata gtcattaaat aaagacctcc taactttatt taataaaatc
    78601 ctaaactttt ttcatcacaa tctcctaatg aagccaccca atcaggtggc ttttttgcgt
    78661 ggtgaggtgc tggtgataga aattttttgc aaaatagtaa aattttagaa aagttaagct
    78721 agttttaagt ttcgtcttgt atcatgtagt tattaaataa agacctccta actttattta
    78781 ataaaatcct aaacttttct ttttcataat aatctccctt aactccaccc aatcaggtgg
    78841 agttttttag ctctatttca ggcttttggg gactattcta aaaataattt ttcgatattt
    78901 ttcggtattt ttcggatttt ggtcggggaa ttggcgggga cttttttagc gaatataact
    78961 aagaaatagg tctgtggtcg cttcagctag ttcaaactca atttgattgt aagtgactgt
    79021 taattgaaga actggaacta ctgtaataat gattttgctt gtctagtagt ggcgtattaa
    79081 atgagaagtg acatgtaaga ttgtctcttc gtttacgaaa tcaaaatttc tatgaaattg
    79141 atagaatccc taacgttctc ttaatcttaa ccgtcttgtc gtacagcggt tgaagaaaat
    79201 gtaaaccttt gacaaaattc gtgaactatg ggataataaa aaggaattga gtactagttc
    79261 tatatcatag gctagaaaag accccaagct cacgaccaaa taagcttgag gtcttttttg
    79321 acactatttg tccttgttta gccatttatc gactatacga agaacgacac cgaccacaat
    79381 tggtccgatg atagttttga gtactaattc catcatgggc tatctcacct cctttcgtag
    79441 gcggtgtagc agtgtcgtat aatattatac cacataagtg ctaaacttag gagtcaccca
    79501 atcaggtggc ttttttgttt gtggcttggt tttttgatat aatagagcca tgagtagaat
    79561 tttagataat gagataatgg gggatgagga gttagtagaa cgcacgctcc gtcctcagta
    79621 tttacgtgaa tatatcggac aggataaggt caaggaccag ctacaaatct ttattgaagc
    79681 tgccaaaatg cgggatgaag cgctggatca tgtgctctta tttgggcctc caggtctcgg
    79741 gaaaacgacc atggcctttg ttattgccaa cgaactggga gtcaatctta agcagacgtc
    79801 gggtccagtc attgaaaaag ccggagatct ggtagctatt ttgaatgagt tagagcctgg
    79861 ggatgtcctt tttattgatg agatccatcg tttgccaatg tcagtggaag aggtgcttta
    79921 tagtgctatg gaggacttct acatagatat tatgattggg gctggtgagg gtagtcgtag
    79981 tgttcatttg gagttaccac cttttacctt gattggtgcg acgactcggg ctggtatgct
    80041 ctccaatccg ctacgggcac gttttgggat tacaggccat atggagtatt atgcccatgc
    80101 tgacttgaca gaaattgtcg agcggacggc agatattttt gagatggaaa tcactcatga
    80161 ggcagcatct gagttggccc tacgtagtcg tgggacccct cgtattgcca atcgtctcct
    80221 caagcgcgtg cgcgattttg cccagataat ggggaatggg gtaatcgatg atattattac
    80281 cgataaggct ttgactatgc tggatgttga ccatgaaggt ttggactatg tggatcaaaa
    80341 aatccttcgt accatgattg agatgtacag tggaggacct gttggtctag gaactctttc
    80401 tgtcaatatc gccgaagagc gtgagacagt tgaagacatg tatgagcctt acttgattca
    80461 aaaaggtttt atcatgcgga cacggtctgg acgggtggcg actgctaagg catatgagca
    80521 cttaggttat gaatacagtg aaaaataagc aagaaatctt agaggctttt agagaaaatc
    80581 cagatatgat ggccattctg acgatcatcc gagaccttgg tttgaaagac tcgtagttgg
    80641 cagcaggttc tgtcagaaat ttcatctgga atcttttgtc agacaaatcc ccttttgatc
    80701 atgaaacaga tatagatgtg attttctttg atccagattt ttcttatgag gaaaccttat
    80761 tactggagaa aaagctgaga gaggattttc ctcagtacca gtgggaattg aaaaatcagg
    80821 tctatatgca tcagcacagt cctcacactg cttcctatac cagttctcgt gatgctatga
    80881 gtaagtatcc agaacggtgt acggcagttg gactgcgctt gaatgaagaa tcagattttg
    80941 aactctatgc accttatggt ttggaggata ttttgaattt tcaagttcgt ccaactcctc
    81001 attttttaga aaatgaagac cgaatggaac tctatcaaac acgtttatcc aagaaaaatt
    81061 ggcaggagaa atggaaaaat ttgattttta aaaatactta aggaaacttt aagctaggga
    81121 gtgtacacta agttcataag ttaagaagac cttaacttaa actcctaaaa ctttttcata
    81181 ataatctccc tataaaaata aagtcgccca atcaggcggc ttattttttt gaaaaatggg
    81241 catggtgcct gagaataaat agcttagtga tagaagaaaa tggggaaata tggtataatg
    81301 aaacgataga tttttgaata ggaataagat catgtttgga ttttttaaga aagataaggc
    81361 tgtggaagta gaggttccga cacaggttcc tgctcatatc ggcatcatca tggatggcaa
    81421 tggccgttgg gctaaaaaac gtatgcaacc gcgagttttt ggacataagg cgggcatgga
    81481 agcattgcaa accgtgacca aggcagccaa caaactgggc gtcaaggtta ttacggtcta
    81541 tgctttttct acggaaaact ggacccgtcc agatcaggaa gtcaagttta tcatgaactt
    81601 gccagtagag ttttatgata attatgtccc ggaactacat gcgaataatg ttaagattca
    81661 aatgattggg gagacagacc gcctgcctaa gcaaaccttt gaagctttaa ccaaggctga
    81721 ggaattgact aagaacaaca caggattgat tcttaatttt gctcttaact atggtggacg
    81781 tgctgagatt acacaggcgc ttaagttgat ttcccaggat gttttagatg ccaaaatcaa
    81841 cccaggtgac atcacagagg aattgattgg taactatctc tttactcagc atttgcctaa
    81901 ggacttacga gacccagact tgattatccg tactagtgga gaattacgtt tgagcaattt
    81961 ccttccatgg cagggagcct atagtgagct ttattttacg gacaccttat ggcctgattt
    82021 tgacgaagcg gccttgcagg aagctattct tgcctataat cgtcgtcatc gccgatttgg
    82081 aggagtttag gaggaaatat gacccaggat ttacagaaaa gaaccttgtt tgcagggatt
    82141 gccctggcta ttttcctacc aattttaatg attgggggcc tcttgcttca gatagcaatc
    82201 ggaatcatag ccatgctagc catgcatgaa cttttgaaga tgagaggtct agagaccatg
    82261 acgatggagg gcctcttgac cctctttgca acctttgcat tgaccattcc cttggagaat
    82321 tacctgactt ttttgccagt tgatgggaat gtggttgcct atagtgtttt gatttcaatc
    82381 atgttaggaa cgaccgtttt tagcaagtct tatacgattg aggatgcggt tttccctctt
    82441 gctatgagct tctacgtggg ctttggattt aatgctttac tagatgctcg tgttgcaggt
    82501 ttggacaagg ctctcttagc cttgtgtatc gtctgggcga cagacagtgg tgcctatctt
    82561 gttgggatga actatgggaa acgaaagtta gcaccaaggg tatcgcctaa taaaaccctt
    82621 gagggtgcct tgggtggtat tttaggagca attttagtaa ccattatctt tatgatagtt
    82681 gacagtacag ttgctcttcc atatggaatt tacaagatgt cagtctttgc tattttcttt
    82741 agcattgctg gacaatttgg tgatttacta gaaagttcga tcaaacgtca ttttggtgtt
    82801 aaggattctg ggaaatttat ccctggacat ggtggtgttt tggatcgttt cgatagtatg
    82861 ttgcttgtat ttccaatcat gcacttattt ggactctttt aatcaaaaga cggaggaaac
    82921 gctatgctcg gaattttaac ctttattctg gttttcggga ttattgtagt ggtgcacgag
    82981 ttcgggcact tctactttgc caagaaatca gggattttag tacgtgaatt tgccatcggt
    83041 atgggaccta aaatttttgc tcacattggt aaggatggaa cggcctatac cattcgaatt
    83101 ttgcctctgg gtggctatgt ccgcatggcc ggttggggtg atgatacaac tgaaatcaag
    83161 acaggaacgc ctgttagttt gacacttgct gatgatggta aggttaaacg catcaatctc
    83221 tcaggtaaaa aattggatca aacagccctc cctatgcagg tgacccagtt tgattttgaa
    83281 gacaagctct ttatcaaagg attggttctg gaagaagaaa aaacatttgc agtggatcac
    83341 gatgcaacgg ttgtggaagc agatggtact gaggttcgga ttgcaccttt agatgttcaa
    83401 tatcaaaatg cgactatctg gggcaaactg attaccaatt ttgcaggtcc tatgaacaat
    83461 tttatcttag gtgtcgttgt tttttgggtt ttaatcttta tgcagggtgg tgtcagagat
    83521 gttgatacca atcagttcca tatcatgccc caaggtgcct tggccaaggt aggagtacca
    83581 gaaacggcac aaattaccaa gattggctca catgaggtta gcaactggga aagcttgatc
    83641 caagctgtgg aaacagaaac caaagataag acggcaccga ctttggatgt gactatttct
    83701 gaaaagggga gtgacaaaca agtcactgtt acacccgaag atagtcaagg tcgttacctt
    83761 ctaggtgttc aaccgggggt taagtcagat tttctatcca tgtttgtagg tggttttaca
    83821 actgctgctg actcagctct ccgaattctc tcagctctga aaaatctgat tttccaaccg
    83881 gatttgaaca agttgggtgg acctgttgct atctttaagg caagtagtga tgctgctaaa
    83941 aatggaattg aaaatatctt gtacttcttg gcaatgattt ccatcaatat tgggattttt
    84001 aatcttattc cgattccagc cttggatggt ggtaagattg tgctcaatat cctagaagcc
    84061 atccgccgca aaccattgaa acaagaaatt gaaacctatg tcaccttggc cggagtggtc
    84121 atcatggttg tcttgatgat tgctgtgact tggaatgaca ttatgcgact cttttttaga
    84181 taatcgagga atattatgaa acaaagtaaa atgcctatcc caacgcttcg cgaaatgcca
    84241 agcgatgctc aagttatcag ccatgctctt atgttgcgtg ctggttatgt tcgccaagtt
    84301 tcagcaggtg tttattctta tctaccactt gccaaccgtg tgattgaaaa agctaaaaac
    84361 atcatgcgcc aagaattcga aaagattggt gctgttgaga tgttggctcc agcccttctt
    84421 agtgcagaat tgtggcgtga atcaggtcgt tacgaaacct atggtgaaga cctttacaaa
    84481 ctgaaaaacc gtgaaaaatc agactttatc ttaggtccaa ctcacgaaga aacctttaca
    84541 gctattgtcc gtgattctgt taaatcttac aagcaattgc cactcaacct ttatcaaatt
    84601 cagcccaagt atcgtgatga aaaacgccca cgtaatggac ttcttcgtac acgtgagttt
    84661 atcatgaagg atgcttatag tttccacgct aactatgata gtttggatag tgtttatgat
    84721 gagtacaaag cagcctatga gcgtattttc actcgtagtg gtttagactt caaggctatt
    84781 attggtgacg gtggagccat gggtggtaag gatagccaag aatttatggc cattacatct
    84841 gctcgtacag accttgaccg ctgggttgtc ttggacaagt cagttgcctc atttgacgaa
    84901 attcctgcag aagtgcaaga agaaatcaag gcagaattgc tcaaatggat agtctctggt
    84961 gaagatacca ttgcttactc aagtgagtct agctatgcag ctaacttaga aatggcaaca
    85021 aacgagtaca aaccaagcaa ccgtgttgtc gctgaagaag aagttactcg tgttgcaacg
    85081 ccagatgtta aatcaattga tgaagttgca gctttcctca atgttccaga agaacaaacg
    85141 attaaaaccc tcttctacat tgcagatggt gagcttgttg cagcccttct agttggaaat
    85201 gaccaactca acgaagtcaa gttgaaaaac cacttgggag cagatttctt tgacgttgct
    85261 agcgaagaag aagtggcgaa tgttgttcaa gcaggatttg gttcacttgg accagttggt
    85321 ttgccagaga atattaaaat tattgcagat cgtaaggtgc aagatgttcg caatgcagtt
    85381 gtcggtgcta acgaagatgg ctaccacttg actggtgtga acccaggccg tgattttact
    85441 gcagaatatg tggatatccg tgaagttcgt gagggtgaaa tttccccaga tggacaaggt
    85501 gtccttaact ttgcgcgtgg tattgagatc ggtcatattt tcaaactcgg aactcgctac
    85561 tcagcaagca tgggagcaga tgtcttggat gaaaatggtc gtgctgtgcc aatcatcatg
    85621 ggatgttacg gtatcggtgt cagccgtctt ctttcagcag tgatggagca acacgctcgc
    85681 ctctttgtta acaaaacgcc aaaaggtgaa taccgttacg cttggggaat caatttccct
    85741 aaagaattgg caccatttga tgtgcatttg attactgtca atgtcaagga tgaagaagcg
    85801 caagccttga cagaaaaact tgaagcaagc ttgatgggag ctggttatga agtcttgaca
    85861 gatgaccgta acgaacgtgt cggtgttaaa tttagcgata gtgacttgat tggtcttcca
    85921 atccgtatca ctgttggtaa aaaagcggcc gatggcattg tagaagttaa gatcaaggca
    85981 actggtgaca ccattgaggt tcatgcagat aacgtgcttg aaacgcttga aatcctaagc
    86041 aagaaataaa aactataatc agaagaaaaa caaggaaaaa atgtaactag tttttacctt
    86101 gttttttctg tataatggga gaaatgagta gataaagagg taaatgttat gctaagattt
    86161 ccaaaggatt ttgtctgggg atcctctact tctggaccgc agacagaagg acgtgtagct
    86221 ggtgacggta agggagacaa tctctgggat tactggttcc aagtggagcc aaatcgttac
    86281 tataatggga ttggttcaga taagacatcg actttttatg aaaattggga gcgggatatt
    86341 gagcttttgt tagagactgg tcacacagtc tttcggactt ctattcagtg gtcacggatt
    86401 tttccacaag gctgtggaaa agtcaaccct caaggtgtgg atttttatcg taaggtcttt
    86461 gaggctatta aggctaaagg aatttgtctg ttagtcaatc tctatcattt tgatttacct
    86521 tttgcccttc aagaggatgg tgatggttgg gaaaataagg cgacagtctc agcctatgaa
    86581 gactatgctc gtttttgttt tgagacttat ggagatttag tggatcaatg gattaccttt
    86641 aacgagccca tcgttcctgt agaatttggt tatttttatg atgcccatta tccacataag
    86701 gtggatgcag aggcagctgt taaggtagcc tatcatacac aattggccag cagccgggct
    86761 gttaaggctt gccatgaact tttgcctgat tccaagattg ggattgtcct caacttgaca
    86821 ccggcttatc cacgtagcca gcatcctgct gatgtcaagg cagctcgtat tgcggccctt
    86881 tttcaggccc aatctttctt agatccatct gtcttgggga cttatccaca ggagttggta
    86941 gaaatcttgc atgaacacgg tcttttacct gatgctacag aggaagagtt ggaactcatt
    87001 cgtgataata cggtggactt ccttggtgtg aactactatc aacctttgcg tgttatggct
    87061 cctcgatttg ctaagcatcc agagagtcca ctcttaccag aacattttta cgagccttat
    87121 gtgatgcctg gacgtaaaat caattctcat cgtggttggg agatttatga gcaagggatt
    87181 tatgacatcg cccaaaatat caaggaaaat tatggcaata ttgagtggat gttgactgag
    87241 aatggtatgg gtgttgaagg ggaagaaaaa ttccgtcaag atggaatgat tcaagatgat
    87301 taccgtattg actttgtaaa aggtcatctt cgtgaacttc accgtgccat tgaagatggt
    87361 gccaactgta agggctactt gatttggacc tttattgact gctggtcatg gctcaacagc
    87421 tataaaaatc gctatggttt ggtcgaatta gacttggaaa cgcaagaacg tcgtctgaag
    87481 aaatcaggcc actggttcaa agaattaagc gataataatg gattttaaaa aggactctga
    87541 ctgattatcc caatcggtca gagtttttat gcttacagga gcttaatttg aactatacca
    87601 atttttactc ttgacaagtg aaagaaacaa gtatatactg tttttgctga ttctataaaa
    87661 gatgaattag actataccaa ttttaaggag aaagcacagc ttgcctgtgt cgtatatact
    87721 atgtgtggaa ttgttggtgt tgttggaaac acaaatgcaa ctgatatttt gattcaaggg
    87781 cttgaaaagc ttgaataccg tggctatgat tctgcgggaa tttttgtcct agatggtgct
    87841 gataaccatt tggtgaaggc ggttggtcgt attgcagaat tgtctgccaa gacagctggt
    87901 gttgagggaa caactggtat cggacatact cgttgggcta ctcacggaaa accaactgag
    87961 gacaatgctc acccacaccg ctctgagaca gaacgttttg tcttggtgca taatggggtg
    88021 attgagaact atcttgaaat caaggaagaa taccttgcag gtcaccactt caaggggcag
    88081 acagatactg aaatagccgt tcatttgatt ggaaaatttg cggaagaaga agggctctca
    88141 gttcttgaag ccttcaaaaa agcccttcac atcatccgtg gttcttatgc ctttgccttg
    88201 gttgactcac aagatcctga agtcatctac gtagctaaaa ataaatcacc acttttgatt
    88261 ggtcttggag aaggctataa catggtctgc tcagacgcca tggctatgat tcgtgaaact
    88321 aaccaataca tggaaatcca tgaccaagag ttggtaatcg tcaaggctga tagtgtggaa
    88381 gttcaagact atgatggaaa tcgtcgtgag cgtgctagct acactgctga acttgacttg
    88441 tcagatatcg gtaagggaac ttacccttac tacatgctca aggaaattga cgagcaacca
    88501 actgttatgc ggaaactcat ccaagcctac acagatgagg ctggtcaagt tgtcgtagac
    88561 ccagatatca ttaaggctgt tcaagacgca gaccgcatct acatccttgc agctggaaca
    88621 tcttaccatg caggatttgc ttctaagaaa atgttggaag aattgacaga tacaccagtt
    88681 gaacttggaa tctcatctga gtggggctac ggtatgccac ttctcagcaa gaaaccactc
    88741 ttcatcttta tcagccaatc tggtgaaaca gcggatagtc gtcaagtttt ggtcaaggct
    88801 aatgaaatgg gaattccaag cttaacagtg acaaacgttc caggttcaac cctctcacgt
    88861 gaagccaact ataccatgct ccttcacgca ggtcctgaaa ttgccgtggc atcaactaaa
    88921 gcctatacag cgcaaatcgc agcccttgcc ttccttgcaa aagcagtcgg agaagcaaat
    88981 ggtaatgcta aagcgcaagc ctttgacctg gttcatgaat tgtcaatcgt agctcagtct
    89041 atcgaatcaa ctctttcaga gaaagaaacc attgaagcca aggttcgtga acttcttgaa
    89101 acaactcgta acgcctttta catcggacgt ggtcaagatt actacgtagc catggaagca
    89161 agtctcaaac tcaaagagat ttcttatatc cagtgtgaag gctttgctgc aggagaactc
    89221 aagcacggaa ccattgcctt gattgaagaa ggaacgcctg ttttggctct cttgtcagat
    89281 ccagttcttg ccaatcatac tcgtggaaat atccaagagg tcgcagcccg tggtgccaaa
    89341 gtcctcacta tcgcagaaga gaatgtagcc aaagataccg acgatatcgt ccttacgacc
    89401 gtacatccat acctctcacc aatttcaatg gtcgtaccaa cgcaattagt cgcttacttt
    89461 gcaaccctcc accgtggcct cgatgtggac aaaccacgta accttgccaa gtcagtaacg
    89521 gtagaataag ctaaaaaagt ctagttatct aggccttttt cttgtgagca aattggttgc
    89581 ttgtactcaa gattcgtgtt atactcttcg aaaatctctt caaaccacgt caacgtcgcc
    89641 ttgccgtagg tatggttact gacttcgtca gttctatcca caacctcaaa acactgtttt
    89701 gagcagcctg cagctagctt cctagtttgc tctttgattt tcattgagta ttagaataat
    89761 ttttcaaatt gaagtacaga gatagataag gagaatcaca atggtagaat tgggaatttc
    89821 aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc atgctgaacg
    89881 cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg atgtatatgg
    89941 gattggtgag caccatcggg cggattttgc agtatcagcc ccagagattg ttctggccgc
    90001 tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc tgtcaagcat
    90061 ggacccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa atggacgagc
    90121 ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg gttatgactt
    90181 gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag tcaatgaaaa
    90241 gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag aagtttatcc
    90301 tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg tcgaatcaac
    90361 agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg gtaatccacg
    90421 ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg gtcatgctga
    90481 caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg gtgagcaggc
    90541 ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca aagaccgtcc
    90601 gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggccaa atggcgccat
    90661 gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag aggatttagg
    90721 attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc aggttctgag
    90781 agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt ttgctatgaa
    90841 agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg tacgaaaatt
    90901 aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt tagttctctt
    90961 ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt cctgcaaata
    91021 ggagtttgtt ttcgtttttg attcctgtat ttggaagttc agcttgtcta tctggggttg
    91081 caggtatatt tttcttgcta gagttttcta ccgattcgtt ttgaaccgct tcttttacag
    91141 atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta gcttggctag
    91201 gtttattttc cgcatcagct actttggcat ctggtttagt agaatcaggt ctagcttctg
    91261 gagctgggtc ttgatgttca ggcttggaag gggttgagtc tggtttctct tctgcagttg
    91321 actcatggct agttccattt tgagagactc gaagaacagt agctgtaagg gcattcaatt
    91381 tcaagccttt ttcagtccat tcaagtcctt tcgggttggc aattccgact gatcctgctt
    91441 ggttttcatc tgccaaaact tccgcatttc ttagatgtgc aaaggcagtt cccaaattaa
    91501 attcgcgagc tttttcatcc gcattgacaa agactgcgta gatatcgccg tttggagcag
    91561 tgatttggta gccaatcact acatcctctt tttccacacc attttggcct gggacagtga
    91621 tgaggtggac acggtctttg atatcttgga gactcttaag tcggaaggca tctgtagatt
    91681 gacgaagggc aatcaaacct ttcatatagt cacggctctt gacattttca ggataagctt
    91741 taccatctgt agccttagtc cagtcaaact tgttgactgc gtcgctagaa tcgtaagaat
    91801 catggatgaa gtaaggatag tcaaatgggt tgccgtcctt atcacgcaac aagtgagatt
    91861 tgtttggaac cttatcctct gctactggag tcttgtaggc tgggtcacgg aattgtttag
    91921 tacgtccata ttcctgaccg gagtggataa atggagttcc ttgagctgtc aagaccatga
    91981 gatttccaag tcgtaaacga cggtggattt cagcatagtt ctcagccttg cttgggtctt
    92041 ttttgataga ctgggcaatg atgtcaaaga gggtcaagtt atcatgggct gcgatgtatt
    92101 ggatgacatc tccagggctg tcagcttcaa agttagttgg ttgagcaatg agatttttaa
    92161 agatggtgtt gacatcacgc ttgccacctg tgataaaggc aggttgacct tcgtttggat
    92221 aaccagattt gaggttgtta cggatgtcat ctgaaaagac agcgacagta tcggtatgtt
    92281 tcatccaatc ttggtcagca gctttagtag gcatgttttc atcaccggca taggttctcc
    92341 aaccttcgcc taacatgatt agatttggat tgagggcgcg tgcagccttg taagcttctt
    92401 cgatagaagc ggcgtcatgg tctcccatca tatcgaagcg gaagccatcc actttgtagg
    92461 tatcaactag gtatttgata gagtcaacta ggagccgttt ggtcatatgg tgggttgtcc
    92521 ccaagcgtcc accaccaaag ctagttcgag gtgtgccatc ggcatccata aagtggtagt
    92581 agtttggctc taggtcttca aagatatcga ctttggctgt gtggttataa acgacatcta
    92641 ggatagctcc cataccacgt ttgtggattt cgttgatgag gtttttaaat tctgcgattc
    92701 gtttttctgg attcttagga tcgcttgagt acataccagt caaggagaag tagttttgag
    92761 ggtcatatcc ccagttgtag ttgctgttgc ttgaagcata gtcagacaag cgttcatggt
    92821 ttttcaattc attgacaaag tagtaagaca agactggaag gagctggata tgggttacac
    92881 ccaagtcttt gagatagtct agtttttcaa tgaaggcttc aaaagtccca aatggtttgg
    92941 tcaagtcttt tgcaatggca ggatctgaag tgaagtcacg cacatgagct tcgtagataa
    93001 cggcgtcttc acgagtcttg aaattgtgaa tcttaccata agtcaagtct tgaggtccga
    93061 gtttagctgg atctacaaag gcggctttag ccactttatg ggcatcgtca atcttggcat
    93121 cgtcgctatt ccaagcagca agagatttag cgtaaggatc gagtgcaaga acagttttac
    93181 cttgacgctc gatttggtat tgataatagt agccagtgaa atctgtgatt ccgagtttgt
    93241 ttgtgctgtc tagagtttgt ttccaagttc ctctttcccc tttttcgaga gcgacagttc
    93301 caactacttt gtcagggtca ttcttgtcgt agacaacaac agaaacctta tcagcacttg
    93361 gtgaccaaag ggtcaaatca acttgttttc cttcttcttt taggtcagct cccagtttgc
    93421 catcatagct gtatgtctca tctttcaggc gccagcttgt tttggtagtg aattggtcgg
    93481 aattgtagct aacagtataa ggatgttttg tgtcagagaa atctccgctg taggtcactt
    93541 tcttaccagc ttcatcgatt gcaacatcgg taatagttac cttgtttcct aggtgattag
    93601 tgatgttgga gtgtttgagg atatcttctt ttttagcacc gacaagtgtt gaaaagctac
    93661 tttcaatgct agaagtgcct acgtgttggg ctcctgtcat acggatatca tggacatagt
    93721 atggatttgt gtaaatcgat tcatcatcgt cttttaggaa aatttggcta tgatttttca
    93781 aatctgtgaa cttataattt tctttacgga ttttcacgtc gtctccttgt ttgctctcat
    93841 ctagtaataa aaatccaaat tctcttgcgg cttcattaag aggaatgtcg atatagcggc
    93901 catatttgcc tgtagccgta aagtctgttc cgtcaggcca ttgagcgcta cttggatttt
    93961 ttacatctcc ccagtaccag agagatttct tgtcatagtt gccatctgtg cggtagtagt
    94021 tgacgcgaac agttcctgca ggctgtggct cgtaagagaa aaccttgtaa tcttggtcta
    94081 accaagcttc gttcattttt ggaactagtt tttctacaga tttatcgccg gttagatttt
    94141 ttccagctgt attgttgatg aggaagctaa ttttcttggc ttgttctccc tttaatttga
    94201 catctaggta atagccgtag tcatctttct tggcatcctt gaaggacaaa gctccgtttg
    94261 gccagttttc agatggtttt tcaacatcgt cccaagtcca tagtccttga gcatccttgt
    94321 tttcttcagg aagttttttg acatggatac ggaagtagtt atcttcgatg ggctcttctg
    94381 ccttagtttc agttgttact ggactagtag aagtagttgg ctcacttgaa cgatcttgtc
    94441 cagtttgtgg tgctggatcg gctgggcttg cagcaggttt ttcttctgtt ttctctaggg
    94501 aagcgtttgc atttctaggt gaagaaatat cactttcgtt cttaccagag ccagctgctg
    94561 tatcagtaag aggttgagca agggtggttg tatttctgtt gttgggttcg ttagtggttg
    94621 gtgtactttc gtcggatgag atagttggtg tagccatggc aagcaagaca aggcttgcgc
    94681 cgataaggac agaaccagtt ccatttttga gggaacggat gctgtagacc atttttttct
    94741 cagtgtgaga tggtgttttt ctcataatga ttctccaatc aataaatttc tatatcagta
    94801 tagcatgtag taaaacaata tgcaagcgtt ttctttgatt tgtgaaaaaa attcctactt
    94861 ttgagaagtt ttctgtacta ttttatatat cagtataaat gacggagata aaaatgtcac
    94921 ataagccaag ccgtattatt aggaagatga tgtgttccca gctattttta ttcagaaatt
    94981 gatctctaac attaccaata aaaatgaaaa atatcttgac aagcaaggga aaattttgtt
    95041 acaataatag acggtacttt ttacttttgg tctctcaaga gtgtacaggg acgtgctgac
    95101 aaatgttgca aaagtacaca cagatgatat ctgtcaccaa gtgtatcatc accaaaaata
    95161 aaaaaacaca ggagaatgta gatgcctaca attaaccaat tggttcgcaa accgcgtaaa
    95221 tcaaaagtag aaaaatctaa atcaccagct ttgaacgttg gttacaatag tcataaaaaa
    95281 gttcaaacaa acgtttcttc accacaaaaa cgtggtgttg caactcgtgt tggaacaatg
    95341 acacctaaaa aacctaactc agcccttcgt aaattcgctc gtgtacgttt gagcaacctt
    95401 atcgaagtta ctgcctacat cccaggtatc ggacacaact tgcaagagca cagcgtggtg
    95461 cttcttcgcg gtggacgtgt aaaagacctt ccaggggtac gttaccatat cgtccgtggt
    95521 gcacttgata ctgcaggtgt taacgatcgt aaacaaggcc gttctaaata cggtactaaa
    95581 cgtccaaaag cataaggaaa ggggataaag agaaatgagt cgtaaaaata gagctccaaa
    95641 acgtgacgta ttgccagatc cgctatacaa ttcacaacta gttactcgtc ttatcaaccg
    95701 cgttatgctt gatggtaaac gtggtactgc tgcttcaatc gtttacggtg cttttgagca
    95761 aatcaaagaa gctactggca acgatgcact tgaagtattt gaaacagcta tggaaaacat
    95821 tatgcctgta cttgaagtac gtgcacgtcg tgttggtggt tctaactacc aagtcccagt
    95881 tgaagttcgt ccagaacgtc gtacaacact tggacttcgt tggttggtaa caatcgctcg
    95941 tcttcgtggt gaacacacaa tgcaagaccg tcttgcaaaa gaaatcttgg atgctgctaa
    96001 caacactggt gcagcagtta agaaacgtga agatactcac cgtatggctg aagctaaccg
    96061 tgcattcgca cacttccgtt ggtaagatag gatgcgaaag cgttaagaaa gtcccagaga
    96121 aaatagggaa tcgaagcagg ttgcggttgc aaccaatgag attcatcttt ttctccagac
    96181 ttttagcttg agctcaacta aatcatgatg ctaggaacgg taaggatgca aggtgaaaat
    96241 aggaaactga cgcagtattc gatgaataca aggagtttta tctttttcac gcagcatccc
    96301 gttccagctc atatcggcta actaacttta gcccgggttc aaattagcta aatcgattag
    96361 tattagctat aactcagctt accatctcgt aagttgaaac caacaatagc atgaaaacat
    96421 tgagaacggg taggtcctgc ctatccgttt ttattaaaat cgtgttataa tagaatagaa
    96481 atcaaaaata aataggagaa acaaacctca tggcacgcga attttcactt gaaaaaactc
    96541 gtaatatcgg tatcatggct cacgtcgatg ccggtaaaac aacaactact gagcgtattc
    96601 tttactacac tggtaaaatc cacaaaatcg gtgaaactca cgaaggtgcg tcacaaatgg
    96661 actggatgga gcaagagcaa gaacgtggta tcacgatcac atctgctgcg acaacagctc
    96721 aatggaacaa ccaccgcgta aacatcatcg acacaccagg acacgtggac ttcacaatcg
    96781 aagtacaacg ttctcttcgt gtattggatg gtgcggttac cgttcttgac tcacaatcag
    96841 gtgttgagcc tcaaactgaa acagtttggc gtcaagcaac tgagtacgga gttccacgta
    96901 tcgtatttgc caacaaaatg gacaaaatcg gtgctgactt cctttactct gtaagcacac
    96961 ttcacgatcg tcttcaagca aatgcacacc caatccaatt gccaatcggt tctgaagatg
    97021 acttccgtgg tatcattgac ttgatcaaga tgaaagctga aatctatact aacgaccttg
    97081 gtacggatat ccttgaagaa gacatcccag ctgaatacct tgaccaagct caagaatacc
    97141 gtgaaaaatt gattgaagca gttgctgaaa ctgacgaaga attgatgatg aaatacctcg
    97201 aaggtgaaga aatcactaac gaagaattga aagctggtat ccgtaaagcg actatcaacg
    97261 ttgaattctt cccagtattg tgtggttcag ccttcaaaaa caaaggtgtt caattgatgc
    97321 ttgatgcggt tatcgactac cttccaagtc cacttgacat cccagcaatc aaaggtatta
    97381 acccagatac agacgctgaa gaaattcgtc cagcatctga cgaagagcca tttgcagctc
    97441 ttgccttcaa gatcatgact gacccattcg taggtcgttt gacattcttc cgtgtttact
    97501 caggtgttct tcaatcaggt tcatacgtat tgaatacttc taaaggtaaa cgtgaacgta
    97561 tcggacgtat ccttcaaatg cacgctaaca gccgtcaaga aatcgacact gtttactcag
    97621 gtgatatcgc tgctgccgtt ggtttgaaag atactacaac tggtgactca ttgacagatg
    97681 aaaaagctaa aatcatcctt gagtcaatca acgttccaga accagttatc caattgatgg
    97741 ttgagccaaa atctaaagct gaccaagaca agatgggtat cgcccttcaa aaattggctg
    97801 aagaagatcc aacattccgc gttgaaacaa acgttgaaac tggtgaaaca gttatctcag
    97861 gtatgggtga acttcacctt gacgtccttg ttgatcgtat gcgtcgtgag ttcaaagttg
    97921 aagcgaacgt aggtgctcct caagtatctt accgtgaaac attccgcgct tctactcaag
    97981 cacgcggatt cttcaaacgt cagtctggtg gtaaaggtca attcggtgat gtatggattg
    98041 aatttactcc aaacgaagaa ggtaaaggat tcgaattcga aaacgcaatc gtcggtggtg
    98101 tggttcctcg tgaatttatc ccagcggttg aaaaaggttt ggtagaatct atggctaacg
    98161 gtgttcttgc aggttaccca atggttgacg ttaaagctaa gctttatgat ggttcatatc
    98221 acgatgtcga ctcatctgaa actgccttca agattgcggc ttcactttcc cttaaagaag
    98281 ctgctaaatc agcacaacca gctatccttg aaccaatgat gcttgtaaca atcactgttc
    98341 cagaagaaaa ccttggtgat gttatgggtc acgtaactgc tcgtcgtgga cgtgtagatg
    98401 gtatggaagc acacggtaac agccaaatcg ttcgtgctta cgttccactt gctgaaatgt
    98461 tcggttacgc aacagttctt cgttctgcat ctcaaggacg tggtacattc atgatggtat
    98521 ttgaccacta cgaagatgta cctaagtcag tacaagaaga aattattaag aaaaataaag
    98581 gtgaagacta atccgtcctc actctagaag gaagtcactt agtggcttcc ttttgtcttt
    98641 agaaaatacc tctaaatatg gtaaaatagt agaagaataa tgtgaggaaa atgaatgtca
    98701 aatagttttg aaattttgat gaatcaattg gggatgcctg ctgaaatgag acaggctcct
    98761 gctttagcac aggccaatat tgagcgagtt gtggttcata aaattagtaa ggtatgggag
    98821 tttcatttcg tattttctaa tattttaccg attgaaatct ttttagaatt aaagaaaggt
    98881 ttgagcgaag aattttctaa gacaggcaat aaagctgttt ttgaaattaa ggctcggtct
    98941 caagaatttt caaatcagct cttgcagtcc tactataggg aagctttctc tgaaggtcca
    99001 tgtgctagtc aaggttttaa gtccctttat caaaatttgc aagttcgtgc tgagggtaat
    99061 cagctattta ttgaaggatc tgaagcgatt gataaggaac attttaagaa gaatcatctt
    99121 cctaatttag ccaaacaact tgaaaagttt ggttttccaa cttttaactg tcaagtcgag
    99181 aagaatgatg tcctgaccca agagcaggaa gaggcctttc atgctgaaaa tgagcagatt
    99241 gttcaagctg ccaatgagga agcgctccgt gctatggaac aactggagca gatggcacct
    99301 cctccagcgg aagagaaacc agtctttgat tttcaagcga aaaaagctgc agctaaaccc
    99361 aagctggata aggcggagat tactcctatg atcgaagtga cgacagagga aaatcgtctg
    99421 gtatttgaag gggttgtttt tgatgtggag caaaaagtga ctagaacagg tcgtgtttta
    99481 atcaacttta aaatgacgga ctatacttca agtttttcta tgcaaaagtg ggttaaaaac
    99541 gaggaagagg cccagaagtt tgacctcatc aagaagaatt cttggctccg agttcgaggg
    99601 aatgtggaga tgaataactt cacacgcgat ttgactatga acgtacagga tctgcaggaa
    99661 gttgttcact atgagcggaa ggatttgatg ccagaaggtg agcgtcgggt tgagtttcat
    99721 gctcatacta acatgtcgac tatggatgct ttgccagagg tcgaagagat tgttgcaaca
    99781 gctgctaagt ggggacacaa ggcggttgct atcacagacc atgggaatgt ccagtccttt
    99841 ccacatggct ataaggcggc taagaaagcg ggaatccagc tgatctatgg gatggaagcc
    99901 aatatcgtgg aggaccgtgt ccctatcgtc tataacgaag tggagatgga cttatcagaa
    99961 gcaacctacg tggtctttga cgtggaaacg acgggacttt cagctatcta taatgacttg
   100021 attcaggttg cggcctctaa gatgtacaag gggaatgtta ttgctgaatt tgatgaattt
   100081 atcaatcctg ggcatccctt gtcagctttt actacagagt taactggaat tacagatgat
   100141 catgtcaaaa atgccaaacc actagaacaa gttttgcaag aattccaaga attttgcaag
   100201 gatacggtcc tagttgccca caatgctacc tttgacgttg gctttatgaa tgctaattat
   100261 gagcgtcatg atcttccaaa gattagtcag ccagttattg atacgctgga gtttgctaga
   100321 aacctctatc ctgagtataa acgccatggt ttggggcctt tgaccaagcg ttttggtgtg
   100381 gccttggaac atcaccacat ggccaactac gatgcggaag cgactggtcg tctgcttttc
   100441 atctttatca aagaggtagc agaaaaacat ggtgtgaccg atttagctag actcaacatt
   100501 gatctaatca gtccagattc ttacaaaaaa gctcggatca agcatgcgac catctatgtc
   100561 aagaatcagg taggtctaaa aaatatcttt aagctggttt ccttgtctaa taccaagtat
   100621 tttgaaggag tgtcacggat tccgagaacg gttctagatg cccatcgaga gggcttgatt
   100681 ttaggttcag cctgttcaga gggtgaagtt tttgacgtgg tcgtttctca aggtgtggat
   100741 gcggcggttg aggtggccaa gtattatgac tttatcgagg tcatgccacc ggctatctat
   100801 gcgcccttga ttgctaaaga gcaggtcaag gatatggagg aactccagac cattattaag
   100861 agtttgatag aggttggaga ccgccttggc aagcctgttt tggctacggg aaatgttcac
   100921 tatatcgaac cggaagaaga gatttatcgt gaaattatcg tccgtagttt gggacagggt
   100981 gcgatgatta accgaactat cggtcatggt gaacatgccc aaccagcacc acttccaaag
   101041 gctcattttc gaacgactaa tgagatgttg gatgaatttg cctttttggg agaggaactg
   101101 gctcgtaaac tggttattga aaacactaat gccttggcag aaatatttga acccgttgaa
   101161 gtcgttaagg gtgacttgta tacgcctttc atcaacaagg ctgaagaaac agttgctgag
   101221 ttgacctata agaaagcttt tgagatttat ggaaatccgc tgccagatat tgttgatttg
   101281 cggattgaaa aagaattaac atccatactg gggaatggat ttgctgtgat ttatctggca
   101341 tcgcagatgc tggtgcaacg ttctaatgaa cggggttatt tggttggttc tcgtgggtct
   101401 gtcggatcta gtttcgttgc gaccatgatt gggattacgg aggtcaatcc tctctctcct
   101461 cactatgtct gtggtcagtg tcagtacagt gagtttatca cagatggttc gtacggttca
   101521 ggatttgata tgccccataa ggactgtcca aactgtggtc acaaactcag taaaaacgga
   101581 caggatattc cgtttgagac cttccttggt tttgatgggg ataaggttcc tgatattgac
   101641 ttgaacttct cgggagaaga tcagcctagc gcccacttgg atgtgcgtga tatctttggt
   101701 gaagaatatg ccttccgtgc gggaacggtt ggtacggtag ctgccaagac tgcctatgga
   101761 tttgtcaagg gttacgagcg agattatggc aagttttatc gtgatgcaga agtagaacgc
   101821 ctcgctcaag gagcggcggg tgtcaagcgg acaacaggcc aacacccggg gggaatcgtt
   101881 gttattccga actacatgga tgtctacgat tttacgcctg tccagtatcc agcagatgat
   101941 gtcacggctg aatggcagac cactcacttt aacttccacg atatcgatga gaacgtcctc
   102001 aaactcgatg tactgggaca tgatgatccg actatgattc gaaaacttca ggatttgtct
   102061 ggtattgacc ctaataaaat tcctatggat gacgaaggcg tgatggcact cttttctggg
   102121 actgatgtgc taggggtaac acctgaacaa attggaacgc ctacgggtat gttggggatt
   102181 ccagagtttg gaacaaattt cgtacgtgga atggtagacg aaacccatcc gacaaccttt
   102241 gcggaattgc ttcagctgtc tggtctgtcc cacggtactg atgtttggtt ggggaatgct
   102301 caggatctga ttaagcaagg aatagcggac ctatcgactg ttatcggttg tcgggacgac
   102361 atcatggttt acctcatgca tgcgggtctg gaacctaaga tggcctttac cattatggaa
   102421 cgggtacgta agggtttgtg gctaaagatt tcagaagagg agagaaatgg ctatatcgaa
   102481 gcaatgaagg ctaataaggt gccagagtgg tatatcgaat cctgtgggaa aattaagtac
   102541 atgttcccta aggcccatgc ggcagcctac gttatgatgg ccttgcgtgt agcttacttc
   102601 aaggttcacc atcctattta ttactactgt gcttacttct ccattcgtgc taaggctttt
   102661 gatatcaaga ccatgggtgc gggcttggag gtcatcaagc gcagaatgga agaaatctct
   102721 gaaaaacgga agaacaatga agcctctaat gtggaaatcg atctctatac aactcttgag
   102781 attgtcaatg agatgtggga acgaggtttc aagtttggta aattagatct ctactgtagt
   102841 caggcgacag agttcctcat cgacggggat acccttatcc caccatttgt agcaatggat
   102901 ggtctgggag agaacgttgc caagcaactg gtgcgggcgc gtgaagaggg agaattcctc
   102961 tctaaaacag aactacgcaa gcgtggtgga ctctcatcaa ccttggttga aaagatggat
   103021 gagatgggta ttcttggaaa tatgccagag gataaccagt tgagtttgtt tgatgagttg
   103081 ttttaaaaaa ttgcttaata atctattaaa agaggctaac gtatatccaa tagatttaca
   103141 ttagctttct tttttgttaa aatagtctat ggaaagaggg tgagagtatg tcaaagatga
   103201 gtataagcat ccgtctggat agtgaggtta aggagcaggc ccaacaggtg tttagtaatc
   103261 tgggaatgga tatgacaaca gctattaata ttttccttcg tcaggcaatt caatatcagg
   103321 gattaccttt tgatgttaga ctagacgaaa atcggaagtt gctccaagtg ttaacggatt
   103381 tagaccaaaa tcgtaacatg agccagtctt ttgaatcagt ctcagatttg atggaggact
   103441 tacgtgctta agattcgtta tcataaacag tttaaaaaag attttaagtt ggctatgaag
   103501 cgtggtttga aggcagaatt attagaagaa gttttgaatt ttctggttca agaaaaagaa
   103561 catcctgcca gatatcgtga tcattcattg acggcatcca agcattttca aggagttcgt
   103621 gaatgccata cccagccaga ttggcttttg gtttataaag tagacaagtc ggaattgatt
   103681 ttaaatttgc tgaggacagg cagtcacagt gatttatttt aatctatttt aagggggttc
   103741 tcatgaaact aagaatattt gcggaagata agccggctaa gaaggtattt gaatatcaat
   103801 tagaacttgc tgatcgtaca attcttctat cgacagcact cttgtcaggt gctattgctt
   103861 tagcaggaat cttttctgct ttgagagaaa aataaaaata gaaaagagaa aacagaatgg
   103921 ttttaccaaa ttttaaagaa aatctagaaa aatatgcgaa attgttggtt gcgaacggaa
   103981 ttaacgtgca acctggtcac actttggctc tctctattga tgtggagcaa cgtgaattgg
   104041 cacatctaat cgtgaaagaa gcttatgcct tgggtgcgca tgaggtcatc gttcagtgga
   104101 cagatgatgt gattaaccgt gagaaattcc tccatgcccc gatggagcgt ttggacaatg
   104161 tgccagaata caagattgct gagatgaact atctcttgga gaataaggct agccgtcttg
   104221 gagttcgttc atctgatcca ggtgccttga acggagtgga cgctgacaag ctttcagctt
   104281 ctgctaaagc tatgggactt gccatgaagc ctatgcgtat cgcaactcaa tctaacaagg
   104341 ttagctggac tgtagcagct gcagcaggac ttgagtgggc taagaaagtc ttcccaaatg
   104401 ctgcgagcga tgaagaagca gttgatttcc tttgggacca aattttcaaa acttgccgtg
   104461 tctacgaagc agatcctgtt aaggcctggg aagagcatgc agctatcttg aagagcaagg
   104521 ccgatatgct taataaggag caattttcag cccttcacta cacagcgcca ggaacagatt
   104581 taacacttgg tttgccaaag aaccatgttt gggaatcagc tggtgctgtc aatgcacagg
   104641 gcgaaggatt cttgccaaat atgccgacag aagaggtctt cacagcacct gacttccgtc
   104701 gtgcagatgg ttatgtcact tctacaaaac cgcttagcta caacggaaat attattgaag
   104761 gcattaaggt gacctttaag gatggacaaa tcgtagatat cactgctgag aagggtgatc
   104821 aggttatgaa agaccttgtc tttgaaaatg tgggtgcgcg tgccttgggt gaatgtgcct
   104881 tggtaccaga tccaagtcca atttctcagt caggcattac cttctttaac acccttttcg
   104941 atgaaaatgc gtcaaaccac ttggctatcg gtgcagccta tgcgactagc gttgttgatg
   105001 gagcggagat gagcgaagag gagcttgaag ctgcagggct taaccgttca gatgttcacg
   105061 tagactttat gattggttct aaccaaatgg atatcgatgg tattcgtgag gatggaacgc
   105121 gagtacctct tttccgtaat gggaattggg caaattaagg agataatatg ttaggaagta
   105181 tgttcgttgg tctcctagtg ggatttttag caggtgctat gaccaatcgt ggagagcgaa
   105241 tgggatgttt tggaaaaatg tttctcggtt ggatcggagc ctttctaggt cacttgctct
   105301 ttggaacttg ggggccagtt ttatcaggaa cagctattat cccagcgatt ttaggagcca
   105361 tgattgtttt agctattttt tggagacgag gaagttaatt tcctaaatct gatactcaat
   105421 gaaaatcaaa gagcaaacta ggaaactagc cgcaggttgc tcaaagcact gctttgaggt
   105481 tgcagataga actgacgaag tcagctaaaa acactgtttt gaggttgcag atagaactga
   105541 cgaagtcagc taaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacat
   105601 atatacggca aggcgacgtt gacgcggttt gaagagattt ttgaagagta tgaaacgaaa
   105661 aggaggttgg tcattgtact agcctccttt tgatatgata taatagttct atgagattag
   105721 ataaattttt agttgcctgt gcggtgggaa gtcggactga ggtcaaaaac ttgctcaagg
   105781 ctgggcgcgt gactgtaaat ggtaaaaaag aaaaatcagc taaattgcag attgatgaaa
   105841 aaatagatga gattcgcttt gatgggcaag tgttggagta tgaagagttt gtctactaca
   105901 tgatgaacaa gcccaaagga gttatctcag cgactgagga tcccaagcac agaaccgttc
   105961 tggacttgtt ggatgacttg gcgcggagta aggaagtttt cccagtagga cgcttggata
   106021 ttgacacgca tggtcttttg ctcttgacca atgatggtca gctggctcat gttcttcttt
   106081 cgcccaagcg tcatgtggac aagacttatc tggcacaagt caagggaatc atgacccaag
   106141 aagatgtgga gacatttgct gagggtattc ctctcaaaga ctttacctgt caacccgcta
   106201 tactggagct tgtatccata gatacagaaa agaatcaaag ccaaatccgt gtgaccattg
   106261 cagaagggaa gtttcatcag atcaagcgta tggtgggcta ctgtggcaag gaagtggtgg
   106321 acttgcaacg attgactatg ggaactttag tattagatga gaacctagaa cgaggggaat
   106381 ggcgtcgctt gaccaaggaa gaattagaaa ttctccgcgc taatattatt taatttagtt
   106441 taatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggctg tacttgagta
   106501 cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtataaat tcgaaaaagg
   106561 tgagggacaa tgtcctcgcc ttttatgttt tttagttgct tcctttgtga aaagagttat
   106621 aatagactgt agaataaaag gaggaatcta tgaacgcgat tcaagaatca tttactgata
   106681 aactatttgc caactatgaa gcaaatgtaa aataccaagc gattgaaaat gctgccagcc
   106741 acaacggaat ttttgcagct ctggaacgtc gccaaagcca tgtagacaac acacctgttt
   106801 tctcattgga tttaaccaag gacaaggtca ctaaccagaa agcgtctggt cgttgctgga
   106861 tgtttgcggc tctcaacacc ttccgccaca aactcatctc gcaatacaaa ttggagaact
   106921 ttgagttgtc acaagcccac actttcttct gggataagta tgagaaatca aactggttct
   106981 tggagcaagt cattgcgact tcagaccaag aattgactag ccgcaaggtt agcttcttac
   107041 tccaaacacc tcaacaagat ggtggtcaat gggatatggt cgtttccctc tttgaaaaat
   107101 acggtgtcgt gcctaagtca gtttatcctg agtctgtttc atctagcagc agtcgtgagc
   107161 taaatgcggt ccttaataaa ttgcttcgtc aagatgctca aatcttgcgt gatttgcttg
   107221 tttctggtgc agatcaagtg actgttcaag ctaagaaaga agacctcttg caagaaatct
   107281 ttaactttct tgctatgtca ttaggacttc caccacgcaa gtttgacttt gcttatcgcg
   107341 ataaagataa caactacaaa agtgaaaaag gaatcacacc acaagagttc tacaagaaat
   107401 atgtcaatct tcctttagaa gactacgttt ctgttatcaa tgctccaact gctgataaac
   107461 cttacggaaa atcttacaca gttgagatgt tggggaatgt ggttggtagc cgtgcagttc
   107521 gttacatcaa cgttccaatg gagcgcttga aagaattggc gattgcccaa atgcaagcag
   107581 gtgagactgt ttggtttggt tctgatgtcg gccagctcag taaccgtaag gctggaatcc
   107641 ttgcgacaga tgtttatgac tttgaatcaa gcatggacat taaacttact caagacaagg
   107701 ctggacgttt ggactatagc gaaagcttga tgacccacgc catggtcttg acaggtgttg
   107761 acttggacga aaatggtaaa tcaaccaagt ggaaggttga aaactcatgg ggagacaagg
   107821 tcggtacaga tggttacttt gttgcctcag acgcttggat ggacgaatac acataccaaa
   107881 tcgttgttcg taaggaattg ctgacagcag aagaacaagc tgcctatgga gcagaaccaa
   107941 ttgtacttgc accatgggat ccaatgggag ccttggctga ataaaagcat agaaaaaagg
   108001 aatcagattt tagaacctgg ttccttttta gggctctata atatttgtag tg
//
LOCUS       DAVHBD010000002        79645 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000002 DAVHBD010000000
VERSION     DAVHBD010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.002"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(4..1671)
                     /locus_tag="VVK04_000118"
     CDS             complement(4..1671)
                     /locus_tag="VVK04_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU3988840.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(1674..2039)
                     /locus_tag="VVK04_000119"
     CDS             complement(1674..2039)
                     /locus_tag="VVK04_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU3988841.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(2196..2384)
                     /locus_tag="VVK04_000120"
     CDS             complement(2196..2384)
                     /locus_tag="VVK04_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU3988842.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(2647..2845)
                     /locus_tag="VVK04_000121"
                     /pseudo
     CDS             complement(2647..2845)
                     /locus_tag="VVK04_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(3100..4644)
                     /locus_tag="VVK04_000122"
     CDS             complement(3100..4644)
                     /locus_tag="VVK04_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU3988843.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            4857..5159
                     /gene="gatC"
                     /locus_tag="VVK04_000123"
     CDS             4857..5159
                     /gene="gatC"
                     /locus_tag="VVK04_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU3988844.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPKKDNYYIKVPAILDDGGDA"
     gene            5159..6625
                     /gene="gatA"
                     /locus_tag="VVK04_000124"
     CDS             5159..6625
                     /gene="gatA"
                     /locus_tag="VVK04_000124"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU3988845.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            6625..8067
                     /gene="gatB"
                     /locus_tag="VVK04_000125"
     CDS             6625..8067
                     /gene="gatB"
                     /locus_tag="VVK04_000125"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU3988846.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISNEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            8196..8756
                     /gene="efp"
                     /locus_tag="VVK04_000126"
     CDS             8196..8756
                     /gene="efp"
                     /locus_tag="VVK04_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU3988847.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            8778..9167
                     /locus_tag="VVK04_000127"
     CDS             8778..9167
                     /locus_tag="VVK04_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU3988848.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            9160..9582
                     /gene="nusB"
                     /locus_tag="VVK04_000128"
     CDS             9160..9582
                     /gene="nusB"
                     /locus_tag="VVK04_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU3988849.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLSAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(9632..9868)
                     /locus_tag="VVK04_000129"
     CDS             complement(9632..9868)
                     /locus_tag="VVK04_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3988850.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(10350..10535)
                     /gene="briC"
                     /locus_tag="VVK04_000130"
     CDS             complement(10350..10535)
                     /gene="briC"
                     /locus_tag="VVK04_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU3988851.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(10693..11460)
                     /locus_tag="VVK04_000131"
     CDS             complement(10693..11460)
                     /locus_tag="VVK04_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU3988852.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQVVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(11457..12323)
                     /locus_tag="VVK04_000132"
     CDS             complement(11457..12323)
                     /locus_tag="VVK04_000132"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU3988853.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(12360..13727)
                     /gene="accC"
                     /locus_tag="VVK04_000133"
     CDS             complement(12360..13727)
                     /gene="accC"
                     /locus_tag="VVK04_000133"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU3988854.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(13739..14161)
                     /gene="fabZ"
                     /locus_tag="VVK04_000134"
     CDS             complement(13739..14161)
                     /gene="fabZ"
                     /locus_tag="VVK04_000134"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU3988855.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(14158..14643)
                     /locus_tag="VVK04_000135"
     CDS             complement(14158..14643)
                     /locus_tag="VVK04_000135"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU3988856.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(14646..15881)
                     /gene="fabF"
                     /locus_tag="VVK04_000136"
     CDS             complement(14646..15881)
                     /gene="fabF"
                     /locus_tag="VVK04_000136"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU3988857.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(15903..16634)
                     /gene="fabG"
                     /locus_tag="VVK04_000137"
     CDS             complement(15903..16634)
                     /gene="fabG"
                     /locus_tag="VVK04_000137"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU3988858.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(16668..17588)
                     /gene="fabD"
                     /locus_tag="VVK04_000138"
     CDS             complement(16668..17588)
                     /gene="fabD"
                     /locus_tag="VVK04_000138"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU3988859.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEATPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(17581..18555)
                     /gene="fabK"
                     /locus_tag="VVK04_000139"
     CDS             complement(17581..18555)
                     /gene="fabK"
                     /locus_tag="VVK04_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU3988860.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(18674..18898)
                     /locus_tag="VVK04_000140"
     CDS             complement(18674..18898)
                     /locus_tag="VVK04_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU3988861.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(18958..19932)
                     /locus_tag="VVK04_000141"
     CDS             complement(18958..19932)
                     /locus_tag="VVK04_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU3988862.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(19932..20366)
                     /locus_tag="VVK04_000142"
     CDS             complement(19932..20366)
                     /locus_tag="VVK04_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU3988863.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(20460..21245)
                     /locus_tag="VVK04_000143"
     CDS             complement(20460..21245)
                     /locus_tag="VVK04_000143"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU3988864.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            21570..22934
                     /locus_tag="VVK04_000144"
     CDS             21570..22934
                     /locus_tag="VVK04_000144"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU3988865.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            22937..23308
                     /locus_tag="VVK04_000145"
     CDS             22937..23308
                     /locus_tag="VVK04_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU3988866.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            23521..24795
                     /gene="serS"
                     /locus_tag="VVK04_000146"
     CDS             23521..24795
                     /gene="serS"
                     /locus_tag="VVK04_000146"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU3988867.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(24820..25719)
                     /locus_tag="VVK04_000147"
     CDS             complement(24820..25719)
                     /locus_tag="VVK04_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU3988868.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLTE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(25829..26377)
                     /locus_tag="VVK04_000148"
     CDS             complement(25829..26377)
                     /locus_tag="VVK04_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU3988869.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(26595..27917)
                     /locus_tag="VVK04_000149"
     CDS             complement(26595..27917)
                     /locus_tag="VVK04_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU3988870.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(28008..28096)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(28260..30596)
                     /locus_tag="VVK04_000150"
     CDS             complement(28260..30596)
                     /locus_tag="VVK04_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU3988871.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLIQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(30700..31248)
                     /locus_tag="VVK04_000151"
     CDS             complement(30700..31248)
                     /locus_tag="VVK04_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU3988872.1"
                     /translation="MISLLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(31245..31547)
                     /gene="zapA"
                     /locus_tag="VVK04_000152"
     CDS             complement(31245..31547)
                     /gene="zapA"
                     /locus_tag="VVK04_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU3988873.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            31634..32515
                     /locus_tag="VVK04_000153"
     CDS             31634..32515
                     /locus_tag="VVK04_000153"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU3988874.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPTLKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     VKLHFKNTEKAKKRLER"
     gene            32519..33133
                     /gene="lepB"
                     /locus_tag="VVK04_000154"
     CDS             32519..33133
                     /gene="lepB"
                     /locus_tag="VVK04_000154"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU3988875.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            33261..35627
                     /locus_tag="VVK04_000155"
     CDS             33261..35627
                     /locus_tag="VVK04_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU3988876.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(35675..36958)
                     /locus_tag="VVK04_000156"
     CDS             complement(35675..36958)
                     /locus_tag="VVK04_000156"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU3988877.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTNQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(37119..37511)
                     /locus_tag="VVK04_000157"
     CDS             complement(37119..37511)
                     /locus_tag="VVK04_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU3988878.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(37797..38819)
                     /gene="cbpF"
                     /locus_tag="VVK04_000158"
     CDS             complement(37797..38819)
                     /gene="cbpF"
                     /locus_tag="VVK04_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEU3988879.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPTTGI
                     MQTGWQFLGNRWYYLHSSGAMATGWYQDGSTWYYLDAENGDMRTGWQYLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYTYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(38838..39659)
                     /gene="cbpG"
                     /locus_tag="VVK04_000159"
     CDS             complement(38838..39659)
                     /gene="cbpG"
                     /locus_tag="VVK04_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU3988880.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTNQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(39740..39979)
                     /locus_tag="VVK04_000160"
     CDS             complement(39740..39979)
                     /locus_tag="VVK04_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988881.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISNTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(40129..40395)
                     /locus_tag="VVK04_000161"
                     /pseudo
     CDS             complement(40129..40395)
                     /locus_tag="VVK04_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(40486..40731)
                     /locus_tag="VVK04_000162"
                     /pseudo
     CDS             complement(40486..40731)
                     /locus_tag="VVK04_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(40656..40887)
                     /locus_tag="VVK04_000163"
                     /pseudo
     CDS             complement(40656..40887)
                     /locus_tag="VVK04_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(40888..41520)
                     /locus_tag="VVK04_000164"
     CDS             complement(40888..41520)
                     /locus_tag="VVK04_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3988882.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(41534..42529)
                     /locus_tag="VVK04_000165"
     CDS             complement(41534..42529)
                     /locus_tag="VVK04_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU3988883.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(42526..43224)
                     /locus_tag="VVK04_000166"
     CDS             complement(42526..43224)
                     /locus_tag="VVK04_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU3988884.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KIVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(43302..44312)
                     /locus_tag="VVK04_000167"
     CDS             complement(43302..44312)
                     /locus_tag="VVK04_000167"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU3988885.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAETCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(44296..45303)
                     /locus_tag="VVK04_000168"
     CDS             complement(44296..45303)
                     /locus_tag="VVK04_000168"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU3988886.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLAIYGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIAAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(45290..46243)
                     /gene="mvaD"
                     /locus_tag="VVK04_000169"
     CDS             complement(45290..46243)
                     /gene="mvaD"
                     /locus_tag="VVK04_000169"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU3988887.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(46225..47103)
                     /gene="mvk"
                     /locus_tag="VVK04_000170"
     CDS             complement(46225..47103)
                     /gene="mvk"
                     /locus_tag="VVK04_000170"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU3988888.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(47225..48244)
                     /gene="cbpC"
                     /locus_tag="VVK04_000171"
     CDS             complement(47225..48244)
                     /gene="cbpC"
                     /locus_tag="VVK04_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU3988889.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMTTGWYQEGITWYYLDQPNGDMKTGWQYLGNKWYYLRSS
                     GAMVTGWYQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVQ"
     gene            complement(48342..49031)
                     /locus_tag="VVK04_000172"
     CDS             complement(48342..49031)
                     /locus_tag="VVK04_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3988890.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(49043..50467)
                     /gene="gndA"
                     /locus_tag="VVK04_000173"
     CDS             complement(49043..50467)
                     /gene="gndA"
                     /locus_tag="VVK04_000173"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU3988891.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(50543..51937)
                     /gene="mapZ"
                     /locus_tag="VVK04_000174"
     CDS             complement(50543..51937)
                     /gene="mapZ"
                     /locus_tag="VVK04_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU3988892.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(51950..53107)
                     /locus_tag="VVK04_000175"
     CDS             complement(51950..53107)
                     /locus_tag="VVK04_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU3988893.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(53192..53572)
                     /gene="rnpB"
                     /locus_tag="VVK04_000176"
     ncRNA           complement(53192..53572)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VVK04_000176"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(53593..53922)
                     /gene="gpsB"
                     /locus_tag="VVK04_000177"
     CDS             complement(53593..53922)
                     /gene="gpsB"
                     /locus_tag="VVK04_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU3988894.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(53992..54519)
                     /locus_tag="VVK04_000178"
     CDS             complement(53992..54519)
                     /locus_tag="VVK04_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU3988895.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFENHGENLNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            54585..55181
                     /gene="recU"
                     /locus_tag="VVK04_000179"
     CDS             54585..55181
                     /gene="recU"
                     /locus_tag="VVK04_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU3988896.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            55178..57337
                     /locus_tag="VVK04_000180"
     CDS             55178..57337
                     /locus_tag="VVK04_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEU3988897.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSINNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(57504..62807)
                     /locus_tag="VVK04_000181"
     CDS             complement(57504..62807)
                     /locus_tag="VVK04_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU3988898.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGADVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALILASVSLALSALFVVKTKKD"
     gene            complement(63108..65090)
                     /locus_tag="VVK04_000182"
     CDS             complement(63108..65090)
                     /locus_tag="VVK04_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3988899.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(65451..66509)
                     /locus_tag="VVK04_000183"
     CDS             complement(65451..66509)
                     /locus_tag="VVK04_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEU3988900.1"
                     /translation="MKKIKEYDILKIMAIILVVLSHSAYYKISSNYGGMDYQQYLNSH
                     SAFTLYKILGKFMEIIYYFHMPLFMAISGVFFSIQIKKDRWNKIEKLLTSKFKRLILP
                     FFVFTLLYSLPLKYISNYYNGVSFWRAITGQFLLLGNSHLWYLYALFIIFIISFYCLR
                     RDTSIFVYLSLYIIHVLSFLIHITLVSAPLQFLFWFSMGFLFESKRRKYNIFLENHKW
                     ISLLFFVLFIFLVVLNFLFKSDFKVLSRFFVDLLAILGSLICYNISYFLSNKTKILDS
                     KLLNLILINGLGIYIFSDTLNYFILSISYFVSDRFMFTSFGIIIIFLIRFVFTLFLGL
                     VFTLLFKKVFPKYSWLVN"
     gene            complement(66590..67690)
                     /gene="glf"
                     /locus_tag="VVK04_000184"
     CDS             complement(66590..67690)
                     /gene="glf"
                     /locus_tag="VVK04_000184"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEU3988901.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAHMKDIEPKNLEEQAIKLIGPDVYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFTHRE
                     ELEASAEKVVFTGMIDQYFDYKHGELEYRSLRFDHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQAKTVITREYPADWKRGDEPYYPINDERNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVLSELGK"
     gene            complement(67702..69114)
                     /locus_tag="VVK04_000185"
     CDS             complement(67702..69114)
                     /locus_tag="VVK04_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003009066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEU3988902.1"
                     /translation="MKVLKNYAYNLSYQLLVIILPIITTPYVTRVFSSDDLGTYGYFN
                     SIVTYFILLATLGVANYGTKVISGHREEIQKNFWGIYSLQLGATVLSLALYVLLCLIL
                     PFMQNPVAYILGLSLVSKGLDISWLFQGLEDFRKITVRNITVKLVGVISIFLFVKSAN
                     DLYLYVFLLTIFELLGQLSMWLPAREFIDRPHFDLEYAKPHLKPVILLFLPQVAISLY
                     VTLDRTMLGALASTKDVGIYDQALKLVNILLTLVTSLGSVMLPRVANLLATGNHRAVN
                     KMHEISFLIYNLVIFPMMAGILIVNDDFVQFFLGQDFQDARYAIAIMSFRMFFIGWTN
                     IMGTQILIPHNQNKEFMISTTAPAIVSVGLNLLFLPKLGYIGAAIVSVSTEALVWAIQ
                     LYFTRRYLKEVPIIGSLTKIVLASAIMYGILLGSKTLIQFSPTINVIVFAVLGGIIYL
                     FAILSLKVVDIKELKHIIKK"
     gene            complement(69219..70235)
                     /locus_tag="VVK04_000186"
     CDS             complement(69219..70235)
                     /locus_tag="VVK04_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU3988903.1"
                     /translation="MSNKILTITVPTYNIENYIGKCIESFKAVNPAYYSDFEVLIIND
                     GSTDNSVQVVKDLMEGSTLDLRIITKENGGHGSTINRGIKEANGKYFKVIDGDDWINV
                     QEFESLLDKLREINTDLVISDYTEQHVYNNSTIFKEFSSYLIPNQETRGIPSKWTPMH
                     ALVYKTSILKDNAITISENTFYVDQEYTMLPLQFVENYIYFKLDIYQYLLGRADQSMN
                     IDIMRKRADHHERVTKRILDLYKESYTQKPELEKVVSDSLQYLVNKQNILYVMNEELD
                     KVYELFSYSEKSGFKFKFETKTKTSNLLYVNYKTKYLFNLVIKNLVKRKANSLEKEFQ
                     EKGF"
     gene            complement(70228..71334)
                     /locus_tag="VVK04_000187"
     CDS             complement(70228..71334)
                     /locus_tag="VVK04_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU3988904.1"
                     /translation="MGKKICIVKWILDDSGGGERVAVSLANELTKKYEVHLIGITTKQ
                     SDLFFKINSQVRYSNFFDHRVRLSKNILKISKMLRKYFIDNEIEVGFGIGISANVFLS
                     LAGIGTQTKVVLCDHTNSITDNREFSQKFQRYVGTKLADKIITLTQEDRENYIKKYGV
                     PEERICYIYNWKEAALSDVSYNKKSTKIVTVGRFDYQKGYDYLIQVAKKVLEKRADWT
                     WEIYGSGNQDEVDKIRDLINENDLQDRLVIKGLEKNQDLIYGDKGIYVMTSRYEGLPL
                     VLLEAQQYNLPIASFSCPTGPNEIVEDGVNGYLVECYDVEAMSNRLLELMNDKELRNR
                     FSSHAKDNIKKFNKDRIIHQWIDLIEEVSGGENV"
     gene            complement(71349..72158)
                     /locus_tag="VVK04_000188"
     CDS             complement(71349..72158)
                     /locus_tag="VVK04_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018369777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEU3988905.1"
                     /translation="MEEDTKLYKIQSKELELLKVLTNICEENNLTYYALGGTLLGAVR
                     HKGFIPWDDDIDIGMPREDYEKFKILAPNLLASNLKIVNNPLNLDITQLVDKNVIVKI
                     ANSESNVFIDIFPLDGYPEKGFFAAKLHSFRLLFQRMLCKISVLDQLEDKDRGTVENL
                     IVKISKMLRIQKVLPKDTLVENLHKVIQKYDFKTSRYVGNVLGRYREREIVPREYFKE
                     PVSLIFEDTMINCPTKYKEYLNEIYGDYMKLPSVEDRVAHNIELISVGDAE"
     gene            complement(72210..73580)
                     /locus_tag="VVK04_000189"
     CDS             complement(72210..73580)
                     /locus_tag="VVK04_000189"
                     /inference="COORDINATES: protein motif:HMM:TIGR04370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEU3988906.1"
                     /translation="MLYILFYLLLLFFIINYAFVRGDYFHPTIIFNFTFLIATLFCIL
                     NAQEYAIEFNGGTVFIVTISMLVFTIITVLSKKIFKTNTFTFKNKLKYLYVSKSLIFT
                     IIIIQILNLIFFYRYEQALFSAYVGGRGSFSQIINNYDQLVKFFTEDLVGLGVRSPFF
                     YRVFNSFISPISYVIIYIICHNYVATRRIDKFQLLVPCLFAIQIFMTGSRGSLFKILT
                     FILVVFYILLLRNKGLSKLSSRFAFKVLIVVVAVAPLFVLYLNATGRSGGVGQDGIIE
                     ALNRELFKYIGAPLLNFNNFIAGHDPYRSDSVYWGEQTFYGFYKFLYSKLHLIDFNIK
                     SIIGSDSFVKSTNGLPTGNVFTTFYTFFYDFTYFGIIPLVSVIALYFVPTYSRILGTE
                     YCAKKYLFDYKLFIYAYLFNDVIMLIFSNRFFESILTVGFLRFLITSATLVWIIKQNI
                     VFKYKK"
     gene            complement(73671..74477)
                     /locus_tag="VVK04_000190"
     CDS             complement(73671..74477)
                     /locus_tag="VVK04_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4422 domain-containing protein"
                     /protein_id="HEU3988907.1"
                     /translation="MERSRLIDVKIIVATHKEVKMPQDSSLYLPIHVGRDGKSDIGFI
                     GDNTGDNISSLNPYYCELTGLYWAWKNLDYNYLGLVHYRRYFTNKSQGYNENVNMDDV
                     ILSRSNVEILLEKSDIIVPKKRKYYIETLYSHYAHTLNGEHLDLARKIIEQNSSEYLS
                     SFDKVMKQRRGYMFNMFIMKKELLDDYLPWLFSILDTMYEQMDLTDYTPFESRLFGRV
                     SELLFNVWLCKKGITPKEVPFMYMERVHLFEKGKSFLMAKFFGKKYGQSF"
     gene            complement(74464..75831)
                     /locus_tag="VVK04_000191"
     CDS             complement(74464..75831)
                     /locus_tag="VVK04_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU3988908.1"
                     /translation="MNGKIVKPSLAIIQSFLVILLTYLLSAVRETEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGKL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            complement(75846..76535)
                     /locus_tag="VVK04_000192"
     CDS             complement(75846..76535)
                     /locus_tag="VVK04_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEU3988909.1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     IGEGKSTTSANIAWAFARAGYKTLLIDGDIRNSVMLGVFKARNKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRNCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGIVLNKFDTSVDKYGSY
                     GDYGDYGKNKK"
     gene            complement(76545..77237)
                     /locus_tag="VVK04_000193"
     CDS             complement(76545..77237)
                     /locus_tag="VVK04_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEU3988910.1"
                     /translation="MKEQNTTEIDVFQLVKTLWKRKLMILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGSYLVKDYREIVLSQDVLEKVVTNLKLD
                     MPAKTLASKVQVTVPADTRIVSISVKDKQPEEASRIANFLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLKIP
                     LLGLVPDFNKIK"
     gene            complement(77246..77977)
                     /gene="cps4B"
                     /locus_tag="VVK04_000194"
     CDS             complement(77246..77977)
                     /gene="cps4B"
                     /locus_tag="VVK04_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEU3988911.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKTLLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMHTSYREIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRVQYFLEQDLVHVIASDMHNLDSRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRRIVMDQLI"
     gene            complement(77979..79424)
                     /gene="cps4A"
                     /locus_tag="VVK04_000195"
     CDS             complement(77979..79424)
                     /gene="cps4A"
                     /locus_tag="VVK04_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU3988912.1"
                     /translation="MSRRFKKSGSQKVKRSVSIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILASSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
BASE COUNT        23576 a        17844 c        14331 g        23894 t
ORIGIN      
        1 atcttattcc acactaaata ggtatgggta aacaggttgt tgaccttggt gaatctcgac
       61 ttcaacgtct tcgaattctt ctacgatttc ttgagcgatt tcattggcaa gttcttcgct
      121 tccgtcttca ccgacataga aggttacgat ttcactgtct tcatccaaca tatgtttcaa
      181 ggtttcagtc aatgtttggt gcatatcagg gtttgacaca agaatttttc catccaccat
      241 acctagatta tcgttttcat ggatttctaa gccatcgatc gttgtatcac gcacggctgt
      301 tgtgacgctt ccgctaacga catcgctaag agcagctgtc atacgctctt gattttcttc
      361 aatggacttg cttggatcaa aggcaagaag acttgtcata ccttgaggaa gagtgcgagc
      421 ctctaccact actgctggtt gctccaaaac ttctgccgca gattgagctg ccatgaagat
      481 gttcttgttg tttggcaaga agatgatgtt acgggcattg acctgttcaa cagccttgat
      541 aaagtcttct gttgaagggt tcatggtttg accgccttcg ataacataat ccacgccttg
      601 agaacagaag atatctgcta gacctttacc agccaccaca gcaatcaaag catactcttt
      661 ttcttcagcc gacttgataa cttgagtagc ttctttctca acctgtgctt cgtgttggtt
      721 acgcatattg tcaactttta ccttgaccaa gctaccatat ttgagacctt cttgcataac
      781 aagtcctgga tcttctgtat gaacatggac tttgacaatt tcatcatcgt taacaacgag
      841 gagagaatcc ccaagctcat ccaagtagtt acggaattca tcgtagtcaa aatctttagc
      901 ataagttgga ccttgcttaa gagctaccat gatttcagta cagtaaccaa acgtgatgtc
      961 ctcagtcgct acgtgaccag ctacagactt atgatgctct acattgatca tctcactcat
     1021 gttagcagga gtcgctacaa agtcctcaga tgcaatatat tcgccagtaa gggctgaaag
     1081 gaaaccttcg tagatgaaga ccaatccttg accacctgag tccacaacgc caacttcttt
     1141 caatactgga agcatgtctg gtgttttagc tagagctgtt ttagcacctt ccaaggctgc
     1201 gcgcatgact tcaacagtgt catctgtttg ctcagctttt ttcttagcac cgatagcagc
     1261 tccacgagaa actgtcaaaa tcgttccttc aacaggtttc atcactgcct tataggcaac
     1321 ttccacacct gattggaagg ccagagccaa gtcttgacct gttaactcgt ctttatcctt
     1381 gatagcttgg gaaaatccac ggaaaagctg agatgtaatc actcctgagt tcccacgcgc
     1441 acccatcaaa agccctttgg caagaatgct cgctacttct ccaactgtag aagctggctt
     1501 gtctgcaact tctttagcac cattttcaat ggtcattccc atatttgtcc cagtatctcc
     1561 atctggaact ggaaagacgt ttaatgaatt gacatattca gcttgcttat tcaagcgagt
     1621 tgatgcagcc tgcaccattt cttgaaataa gctagtagta atttttgaca cggttattct
     1681 cctacaactt tgatattttg aatgtagaca tttacagtct gagcagtaat tccaagctgg
     1741 ttttccaagc taaaggcaac acgctcttga atgttttttg acacttcact aatctttgtt
     1801 ccgtagctta acacggtata tacatcaact gcaatactgc catcttcggc tgcctttacg
     1861 acgacacctt tagaataatt ttccttacct agcagggctt ggaaattatc tttgagggca
     1921 tttttactag ccataccgac cacaccaaaa atctcagttg ctgctccacc tacgacggtt
     1981 gcaatcactt catctgttag ttcgatttga ccatcttttg tattaatttt tacagtcatc
     2041 ctttttacct caactagttg atactctatt ttatcatatt tcagcctaag tgtaaaagca
     2101 gaatgatgta tcagcggata tttactctat ttttcaaacg atgttatacc cacaataaaa
     2161 gaaaaaagac cctaaggtct cctttgcttt tattattaaa cgcgttcaac tttacctgat
     2221 ttcaaagcac gagctgaagc ccaaactttt ttaggtttac catcgataag aacagtaact
     2281 ttttgaaggt ttggttttac ggcacgtttt gtttggttca tcgcgtgtga acggttgttt
     2341 cctgatacag tcttacgacc tgtaaagtaa catactttag ccattgtgtt ttcctcctat
     2401 tagatctaat atagcggatg tgctagcacc acataccgta ctatgttatc acactttctt
     2461 gttttttgca agggaattgg aagatttttt atttgtgtct taaatcaggt cttgcgtgac
     2521 attttctgct ctccacatgc cattgttgat taacagaaca ccagaattaa aattatgtgt
     2581 ataaaaatca tcatatgaaa gtccctcaaa ggggagacga taacctttca gaatactact
     2641 gtcaatctaa acattcacaa tctcactatt caaagtctct agtctttttt ccatcaattg
     2701 gaaccattct cgcggaaggt catcattaaa aacataaaac ttaagattat aatagatgaa
     2761 cacaaagaga ttttattgtt atttcaactt tatccatata agcattatct gcacctaaga
     2821 caatcgcttt tttctcttct tccactcttt atctcatttc tttttattcc catcatatgt
     2881 ttctacgtaa ccattatttt cgcccattcg ttcgtaaaac cataccagtg gagattttag
     2941 atgaagtccc attacggttt acaattttta cattacgaca cggagtttta caaatcgatt
     3001 tcatttgcca aacgtagtta gtaaggcagt tagctagttc gccaaatagc gactagcgtc
     3061 caacaatttg gaactttagt tccaattgtt ggtactgagt cacatcttct cctctaactc
     3121 tacgtctgga tacttgtccg caaaccagcg gagggcaaag tcattttcaa agagaaagac
     3181 tggttggtca aaacggtctt tggctaagat attgcgactt gacgacatcc gttcatccaa
     3241 gtcctcaggc ttgatccaac gaacggtctt tttacccatt gggttcataa ctacttctgc
     3301 attgtactcg ccttccatgc ggtgtttaaa gacttcaaac tggagttgac ctacagcgcc
     3361 tagcatgtac tcacctgttt ggtaattctt ataaagctga atagcacctt cttgcaccaa
     3421 ttgctcaatc cccttgtgga aggatttttg cttcataaca ttcttagcag aaactttcat
     3481 gaaaatttca ggagtaaagg ttggcagtgg ttcaaattca aacttgtttt taccaactgt
     3541 caaggtatcc ccaacttgat aagtaccggt atcgtaaacc ccgataatat cacctgccac
     3601 ggcattgatc acattctcac gactttccgc cataaactga gtaacattag acagtttagc
     3661 ccccttacca gtacgaggga gattgacact catgccgcgc tcaaattcgc cagatacgat
     3721 acggacaaag gcaatacggt cacggtgacg agggtccatg ttggcttgga ttttaaagac
     3781 aaatcctgag aaatccttgt cataaggatc cacaatttca ccgtctgttt tcttgtgacc
     3841 atgtggttct ggagcaaact tgaggaaggt ttcaaggaag gtctgcacac caaagtttgt
     3901 cagggctgaa ccgaaaaaga caggcgtcaa ttctccagcc agaatagctt cctctgaaaa
     3961 ctcattcccg gcttcattta aaagctcaat gtcatccttg acttgctcgt agaaaggatt
     4021 gctgccaaag agtttgtccc cgtcttctag actggcaaaa cgctcatccc ctttgtaaag
     4081 ctctaaacgt tggttataga ggtcatacaa gccctcaaag gctttcccca tcccgatagg
     4141 ccagttcata gggtagctag caatgcccaa gatttcttcc aattcttgca agagatccaa
     4201 aggctcacga ccgtcacggt ccagcttgtt cataaaggta aagactggaa tgccacgatg
     4261 tttcacaacc tcaaacaatt tcttggtttg agcctcgatc cccttggcag agtccacgac
     4321 catgaccgca gcatccaccg ccatcaaggt acgataggta tcttctgaga agtcctcgtg
     4381 ccctggcgtg tctaagatat tcacgcgctt gccgtcgtag tcaaattgca taacagatga
     4441 agtaacagaa atcccacgtt gcttctcgat atccatccag tcagatttag caaaagtccc
     4501 tgttttcttc ccttttaccg taccagcctc acgaatctca cccccaaagt agagtaactg
     4561 ctcagtgatg gttgttttcc ccgcgtccgg gtgggagata atggcaaagg tacgacgttt
     4621 cttaatttct tcttgaatat tcataagttc tctttctttg attctctatt tttcttgttt
     4681 caatagctga gaatgatttt tacattggat tttaccattc ctttcaacac tccattatat
     4741 cggattttag catttttttc aatttctatt tcttttcact tccccctccc ttatttatag
     4801 gaaaatatgg taaaatagaa cagactaaaa atcatcattt cacgaaagga tgcaagatga
     4861 aaattacgca agaagaggta acacacgttg ccaatctttc aaaattaaga ttctctgaaa
     4921 aagaaactgc tgcctttgcg accaccttgt ctaagattgt tgacatggtt gaattgctgg
     4981 gcgaagttga cacaactggt gtcgcaccta ctacgactat ggctgaccgc aagactgtac
     5041 tccgccctga tgtggccgaa gaaggaacag accgtgatcg cttgtttaaa aacgtaccta
     5101 aaaaagacaa ctactatatc aaggtgccag ctatcctaga cgatggagga gatgcctaat
     5161 gacttttaac aataaaacta ttgaagagtt gcacaatctc cttgtctcta aggaaatttc
     5221 tgcaacagaa ttgacccaag caacacttga aaatatcaag tctcgtgagg aagccctcaa
     5281 ttcatttgtc accatcgctg aggagcaagc tcttgttcaa gctaaagcca ttgatgaagc
     5341 tggaattgat gctgacaatg tcctttcagg aattccactt gctgttaagg ataacatctc
     5401 tacagacggt attctcacaa ctgctgcctc aaaaatgctc tacaactatg agccaatctt
     5461 tgatgcgaca gctgttgcca atgcaaaaac caagggcatg attgtcgttg gaaagaccaa
     5521 catggacgaa tttgctatgg gtggttcagg tgaaacttca cactacggag caactaaaaa
     5581 cgcttgggac cacagcaagg ttcctggtgg gtcatcaagt ggttctgccg cagctgtagc
     5641 ctcaggacaa gttcgcttgt cacttggttc tgatactggt ggttccatcc gccaacctgc
     5701 tgccttcaac ggaatcgttg gtctcaaacc aacctacgga acagtttcac gtttcggtct
     5761 cattgccttt ggtagctcat tagaccagat tggacctttt gctcctactg ttaaggaaaa
     5821 tgccctcttg ctcaacgcta ttgccagcga agatgctaaa gactctactt ctgctcctgt
     5881 ccgcatcgcc gactttactt caaaaatcgg ccaagacatc aagggtatga aaatcgcttt
     5941 gcctaaggaa tacctcggtg aaggaattaa cccagaggtt aaggaaacca ttctaaatgc
     6001 cgctaaacac tttgaaaaat tgggtgctat tgtcgaagaa gtcagccttc ctcactctaa
     6061 atacggagtt gccgtatact acatcatcgc ttcatcagaa gcttcatcaa acttgcaacg
     6121 cttcgacggt atccgttacg gctatcgcgc agaagatgca accaaccttg atgaaatcta
     6181 tgtaaacagc cgaagccaag gttttggtga agaggtaaaa cgtcgtatca tgctgggtac
     6241 tttcagtctt tcatcaggtt actatgatgc ctactacaaa aaggctggtc aagtccgtac
     6301 cctcatcatt caagatttcg aaaaagtctt cgcggattac gatttgattt tgggtccaac
     6361 tgctccaagt gttgcctatg acttggactc actcaaccat gacccagttg ccatgtactt
     6421 ggctgacctc ttgaccatac ctgtaaactt agcaggtctc cctggaattt cgattcctgc
     6481 tggattctct caaggtctac ctgtcggtct gcaattgatt ggtcccaagt actctgagga
     6541 aaccatttac caagctgctg ctgcttttga agcaacaaca gactaccaca aacaacaacc
     6601 cgtgattttt ggaggtgaca actaatgaac tttgaaacag tcatcggact tgaagtccac
     6661 gtagagctca acaccaattc aaaaatcttc tcacctactt ctgcccactt tggaaatgac
     6721 caaaatgcca acactaacgt gattgactgg tctttcccag gagttctacc agttctcaat
     6781 aaaggggttg ttgatgccgg tatcaaggct gctcttgccc tcaacatgga catccacaaa
     6841 aagatgcact ttgaccgcaa gaactacttc tatcctgata accccaaagc ctaccaaatt
     6901 tctcagtttg atgagccaat cggttataac ggctggattg aagtcgagct agaagacggt
     6961 acgaccaaga aaatcggtat cgaacgtgcc cacctagagg aagacgctgg taaaaacacc
     7021 catggtacag atggctactc ttatgttgac ctcaaccgcc aaggggttcc cttgattgag
     7081 attgtatctg aggcagatat gcgttctcct gaagaagcct atgcttatct gacagccctc
     7141 aaggaagtta tccagtacgc tggcatttct gacgttaaga tggaggaagg ttcgatgcgt
     7201 gtggatgcca acatctccct tcgtccttat ggtcaagaga aattcggtac caagactgaa
     7261 ttgaagaacc tcaactcctt ctcaaacgtt cgcaaggggc ttgaatacga agtccaacgt
     7321 caagctgaaa tacttcgctc aggtggtcaa atccgccaag aaacacgccg ttacgatgaa
     7381 gctaacaaag caaccatcct catgcgtgtc aaggaagggg ctgctgacta ccgctacttc
     7441 ccagaaccag acctgcctct ctttgaaatc tcaaacgagt ggattgagga aatgcggact
     7501 gagttgccag agtttccaaa agaacgtcgt gcgcgttatg tatctgacct tggtttatca
     7561 gactacgatg ctagtcagtt gactgctaat aaagtcactt ctgacttctt tgaaaaagct
     7621 gttgccctag gtggtgatgc caaacaagtc tctaactggc tccaagggga agtcgctcag
     7681 ttcttgaatg ctgaaggtaa aacactggaa caaatcgaat tgacaccaga aaacttggtt
     7741 gaaatgattg ccatcatcga agacggtact atttcatcta agattgccaa gaaagtcttt
     7801 gtccatctag ctaaaaatgg cggtggcgcg cgtgaatacg tggaaaaagc aggtatggtt
     7861 caaatttcag atccagctat cttgatccca atcatccacc aagtctttgc cgataacgaa
     7921 gctgctgttg ccgacttcaa gtcaggcaaa cgtaacgccg acaaggcctt tacaggattc
     7981 cttatgaagg caaccaaagg ccaagccaac ccacaagttg cccttaaact acttgcacag
     8041 gaattggcga agttgaaaga aaactagaca gaacaaaacc agccctaagg ttggtttttt
     8101 cttctctacc aactcccaat aactattttg gctttatttc cagagtattt tatggtaaaa
     8161 tgaagagtaa taatatttat taaagaggta aaaacatgat tgaagcaagt aaattaaaag
     8221 ctggtatgac ctttgaaaca gctgacggca aattgattcg cgttttggaa gctagtcacc
     8281 acaaaccagg taaaggaaac acgatcatgc gtatgaaatt gcgtgatgtc cgtactggtt
     8341 ctacatttga cacaagctac cgtccagagg aaaaatttga acaagctatt atcgagactg
     8401 tcccagctca atacttgtac aaaatggatg acacagcata cttcatgaat acagaaactt
     8461 atgaccaata cgaaatccct gtagtcaatg ttgaaaacga attgctttac atccttgaaa
     8521 actctgatgt gaaaatccaa ttctacggaa ctgaagtgat cggtgtcacc gttcctacta
     8581 ctgttgagtt gacagttgct gaaactcaac catctatcaa aggtgctact gttacaggtt
     8641 ctggtaaacc agcaacgatg gaaactggac ttgtcgtaaa cgttccagac ttcatcgaag
     8701 caggacaaaa actcgttatc aacactgcag aaggaactta cgtttctcgt gcctaatctc
     8761 tagaaagagg tcattctatg ggaattgaag aacaacttgg cgaaatcgtt atcgccccac
     8821 gtgtacttga aaaaatcatt gctatcgcta ctgcaaaggt agagggtgtt cactcttttt
     8881 caaacagatc agtgtctgat accctttcaa aactttcact cggccgtggc atttatctta
     8941 aaaacgtgga cgaagaactc acagcagata tctatctcta ccttgagtac ggagtaaaag
     9001 ttcctaaggt agcggttgct atccagaaag ctgtcaaaga tgccgtccgt aatatggctg
     9061 atgtagaact cgctgctatc aatattcacg ttgcaggtat cgtcccagat aaaacaccaa
     9121 aaccagaatt gaaagatcta tttgacgagg acttcctcaa tgactagtcc actattagaa
     9181 tctagacgcc aactccgtaa atgcgctttt caagctctca tgagccttga gttcggtacg
     9241 gatgtcgaaa ctgcttgtcg tttcgcctat actcatgatc gtgaagatac ggatgtacaa
     9301 ctttcagcct ttttgataga cctcgtttct ggtgttcaag ctaaaaagga agaactagat
     9361 aagcaaatca ctcagcattt aaaagcaggt tggaccattg aacgcttaac gctcgtggag
     9421 agaaacctcc ttcgcttggg agtctttgaa atcacttcat ttgacactcc tcagctggtt
     9481 gctgttaatg aagctatcga gcttgcaaag gacttctccg atcaaaaatc tgcccgtttt
     9541 atcaatggac tgctcagcca gtttgtaaca gaagaacaat aaaaagaaaa agtgtttgat
     9601 agatatcaaa cacttttttc tttgcctccc actatctaaa aaaatgataa tagatataat
     9661 tgtaaacaaa aatccagata ggttttgcat gattgagaaa gttaaaaaaa ctatggcaga
     9721 gaatcgttaa tctcagattg tcggtagaac gataaacaag ggcaaaaaag aaaccaatca
     9781 gactataata taataaacta attggatctc tgtgagatag tatcaaatgg ctaatcccaa
     9841 agatgatagc agataggata acatccaaat aatacttgga ctagggaaag aaggtgttca
     9901 taaaataccc tctatcaaga gtctcctcaa aaacaggacc gatgattaca ggcaggacaa
     9961 aagataagat agtcgataaa aaggttggtt gtccatttga aagaaccacg gtaaaatact
    10021 catcatgaat attcctatga ttaatcaaat gagcatagcg tgcccaaaaa ttaccgagaa
    10081 tctgataaac cacataagtt gcaaataagg agaagacaaa tgaccagtcc cagctctttt
    10141 tcttttttaa cctccaaatt aatagaaaag gaaacttccc actaatccca ctgttaaaat
    10201 aagagaatag acatcagctc ctaaccctaa aatgatcgtc acatacaatc caattgtttg
    10261 tggtaaatag gtagatagta aaataataag caaaaatatt ccaaattgtc ttagtttctt
    10321 tgtgtttctc atcgtacttt tttgaaagat taccctgttc ggaagccgta cttccaagca
    10381 tctatataag aattaagtgc cccttgcctc atatagggag caaattctct ataatataac
    10441 catctactat atccatcttc ccaaacagca agaccacctg aagtttgctc caagtcctca
    10501 gttgaaataa ctgtaaatgt ttctgtacct gtcattgcaa gtaccttctt aaaatagatt
    10561 gttgtaggct cacatttata gtatatttct tttttgtcta ttttatagcc catctcctca
    10621 actatcaatt tttcaacctg aattgcattt ttccataaaa aatgagacct ttctagtctc
    10681 atttagtcat tcttagtatt ttctaaatcg ttgatagcgt tcttccagca actcttctag
    10741 cggtttttgt gaaagtctag ccagctccgt ttggagttct tttttgacac tcttaatcag
    10801 ttctttacta gaaagtccta cttcagaaat caccttatcc accacgtcca tttctaacag
    10861 ttcatgcgaa gtgattttca tcagttctgc tgcttccatg gcgcgagtac cgtccttcca
    10921 taaaatggaa gcaaagcctt ctggactgag aatggcatag atagaatttt ccagcatcca
    10981 gacacggtcc gcgacagcta gagccagagc cccgcctgaa ccaccttcac cgataataat
    11041 ggcgataata ggaactttca ggtcactcat ttccatgaga ttgcgagcga tagcttcccc
    11101 ttgaccacgt tcttctgctc cgacaccagg ataagcacct gctgtattaa taaaggtcac
    11161 aactggacgg ccaaatttct cagcctgttt catcaaccgc agtgcctttc ggtagccttc
    11221 tggatgtggt tggccaaaat tccgtttgag gttgtcttgc aaactcttgc ctttttggat
    11281 accaaccact gttacaactt ggtctccaag ccaaccaata ccaccaacaa ctgcaccatc
    11341 atcacgaaaa gaacggtcac catgtaattg gataaattca tcaaaaatgc ctgtcgcaaa
    11401 gtccaaggtt gtcaagcgac tctgctcacg cgcttctctg actatttttg caatattcat
    11461 ctaggactcc ctccatgcaa tctgactagg ctagcaatcg tatctggtaa gtctcttctt
    11521 ttgacaatag catccacaaa gccatgttct aataggaatt ctgccttttg gaaatcctca
    11581 ggcaagcttt cacgaaccgt attttcaatc acacgacgcc cagcaaaacc aaccaagctc
    11641 tgtggttcag ccagaatgat atcgccttcc atagcgaaag aagctgtcac accaccagtc
    11701 gttggatctg tcaaaatggt caggtaaaag agaccagcat ttgaatgacg tttaaccgcc
    11761 gcagagatct tagccatctg catgagactc atgattcctt cctgcatacg ggctccacca
    11821 gaggctgtga ataggacaac tggcaatttt tcgacagtcg catactcaaa caaacgagtg
    11881 attttttcac ctacaaccgt acccatagaa gccatgataa agttagaatc cataatccca
    11941 agagccacag tctgaccttt aataagagca gttcctgtca caacggcttc atgcagacct
    12001 gttttttcac gcatagatgc cagtttcttt tggtaaccag ggaaatgcaa gggatccttg
    12061 ctttcaatcc ctgtaaacaa ttctttgaag gttcccatat caatcgtcaa agccaagcgt
    12121 tcttgggcag aaatacgaaa ggtatagcta cagtgcggac agatacgttc acttcccaga
    12181 tccttctgat agatggtatg cttacagcct ggacactggg aaaataattc atctggaacc
    12241 tctggcttag cttgaggttt ttccctaacc gaacgattgg gattgattcg aatatactta
    12301 tcttttttac taaatagagc cattgattcc ccttttcggt ttaaactctt aaagtcattt
    12361 tattcttttt cttgatattt aggtaagaag gtttccatca agaaggaagt atcataatcc
    12421 ccagcaatga cattgcgatc tgaaatgagg tcaagctgga aatctgcatt ggtctgcact
    12481 ccttcaatct ctaattcata gagggcacgt tgcattttca tcaaggcgtc aaaacgattt
    12541 tcgccgtgta ctatgatttt ggcaatcata ctatcataat aaggcggaat ggtataacct
    12601 ggataaactg ctgaatccac gcgcaagcca actccaccac ttggcagata gagattagta
    12661 atcttacctg gacttggagc aaagttaaag gctgggtttt ctgcattgat acgacactcg
    12721 atggcatgac cgcgtaggac aatatcttct tgcttaacag acaaaggctg acctgccgca
    12781 atgcaaatct gttccttaac gatatcaaca cctgaaacaa actctgttac tggatgttct
    12841 acctgaacac gagtattcat ctccatgaaa tagaaattgc tacttgcttc atcaagaaga
    12901 aattcaatgg ttcctgcatt ctcatagcca acaaactctg ccgctcgaac agcagcagca
    12961 cctatttcat gacgcagcgt ttttccgatt gcaatcgagg gactttcttc caaaaccttt
    13021 tggttattcc tttgaagaga acaatcccgc tcacccaagt gaatcacatg tccatgctca
    13081 tcacctagga tttgaacctc aatgtgccga gctggataga taacccgttc tatgtacatg
    13141 gcaccattgc cataattggc cttggcctca ctagaggcag tttcaaaggc agaaacgagg
    13201 tcatctggtt tttcaacctt acgaatccct ttaccacctc cacctgctga agccttgagc
    13261 ataacaggat agccaatttt ttcagcaaca atcaaagctt cttcagagtt atgcacttct
    13321 ccatctgaac ctggtataac aggcacacct gctttaatca tctgagcacg cgcattgatc
    13381 ttatccccca tcatatccat aacatgacca gatggaccga taaacttgat acctacttct
    13441 tcacacatgg tcgcaaattt ggaattttca ctgagaaatc caaaaccagg gtgaatagct
    13501 tctgcctcag tcaagactgc agctgataga actgcattaa tattgagata agactctgtt
    13561 gccttgccag gaccaataca aactgcttca tctgccaaaa gcgtatgaag agcttcctta
    13621 tcagcagttg aataaaccgc taccgtcgca atccccaatt cacgtgccgc acggataata
    13681 cgaaccgcaa tttcaccacg attggcaatt aaaatttttc gaaacatgga gaacctcctt
    13741 agttcccaat tgcaaaagta aggataccac tggctgcaag cttgccatcc acttcagcct
    13801 ttgcttcaac cacagctatg gtgccacgac gttttacaaa agtcgctgtc ataaccaatt
    13861 ggtcgcctgg tacaacttgc ttcttgaact taaccttgtc cataccagcg taaaagacca
    13921 gttttccttt attttcaggt tttgataact ccaacacacc agcagtttgc gccaaggctt
    13981 ccataatcag aacacctggc ataactgggt attgaggaaa gtggccgtta aagaaaggtt
    14041 cgttaatggt cacatttttg atagcaacaa tggtatcctc gctcacttcc aagacacggt
    14101 ccactagaag cataggataa cggtggggaa gagcttcttt gattccttga atatcgatca
    14161 tttgatacgt accaatcctt taccaaactc aaccatttct tcgttagaga cgagaatttc
    14221 cgttaccaca ccatccttag gagctgggat ttcattcatg actttcatgg cttcgataat
    14281 taccaatgtt tgaccttttt tgacactatc accaactgta acgaaggcag gtttatctgg
    14341 tccagcagcc aagtaaacca ctccaacaag tggactctct acaagatttc cctcagtagc
    14401 cacacttgct tcagctggag ctggaacttc ttctgctaca gtctctgctg gagcagatgt
    14461 aggagctact ggactcggtg ttgctagaac gggtgctgga gcgacttgag ttgcaacttc
    14521 aggcacaggt ctcgcttcat tcttgctaaa ctgcaactca tccgtcccat ttttataaga
    14581 aaattctctc aaacttgact ggtcaaattg agtcatcaag tctttaatat cgtttaaatt
    14641 catacttatc tattctccca acgtttgaaa gcaagaactg cattgtggcc tccaaaacca
    14701 aaagtatttg aaatagcgta tggaatttct ttctccaagc cttgtccata aacgacatta
    14761 gcttcgatat aatctgatac ttcacttgtc ccagctgtca ttggtacaaa gttatgacgc
    14821 atagcttcga tggtgacgat agcttctact gcacccgcag cccccagcaa atgtcctgta
    14881 aaagacttgg ttgatgatac aggtacttcc ttaccaagaa cagctacgat agctccactt
    14941 tctccttttt cattggcagg agttgacgtt ccgtgagcat tgacataggc tacttgctct
    15001 ggagaaatct cagcttcttc caaggctagt ttgatggcct tgatagctcc ctgaccttct
    15061 ggatgtggag aagtcatgtg gtaggcatca caagtatttc cgtaaccaac cacttcagcc
    15121 aggatagtag ctccacgttt ttctgcgtgt tcaagacttt ctagaaccaa catccctgaa
    15181 ccttcaccca taacaaaccc attgcgatcc ttatcaaatg ggatcgaagc acgagttgga
    15241 tcctctgtag tagagagagc tgttaaggct tggaaaccag cgatggcaaa aggtgtgata
    15301 gaagcttctg ttcctcccac caacatcaca tcttggaaac caaacttaat ggagcggaag
    15361 gcatccccaa tcgcatcatt tgatgaagag caggcagtat tgatagattt acaaacaccg
    15421 tttgcaccaa aacgcatggc tacattccca gaagccatat ttggtaaagc ttttggaaga
    15481 gtcattggtt tgacacgttt gggtcctttt tcatgaaggc gaagtacctg atcttcaatt
    15541 tccttgattc caccaatacc agatgcaacg ataacaccaa aacgatccct attaagagcc
    15601 tctacatcaa gattggcatg atttacagcc tcttgggctg catacaaggc atataaagaa
    15661 tagttatcaa aacggttggt atcttttttt acaaagtatt tatcgaacgg aaaatcttgg
    15721 atttctgccg cattatgcac atcaaagtca ctatgatcaa attttgtaat gccaccaatg
    15781 ccgattttcc cagttgctaa actattccaa aattcttctg gtgtatttcc gattggagat
    15841 gttactccat aacctgttac cactactcga tttagtttca ttcttttcac ctctagcttt
    15901 cgctacatac ttaagccacc atcaatggca atcacttgac cagttagata atcttggcct
    15961 gctaaaaaca ctgtcaaatc tgcaacctgc tctgcctgcc caaattcttt catcggaatc
    16021 tgagctagtg tagcttcctt aatcttatct gataagatag cggtcatatc agactcaatc
    16081 attcctggag caatcacatt gactcgtata ttccgactag cgacctcgcg tgccacagac
    16141 ttggtaaagc caatcaagcc agccttagaa gcagcatagt tagcttgacc aatattcccc
    16201 atcaaaccaa caacactaga catattaatg atagcacctt ctctggcttt catcatcggt
    16261 ttcaagactg attgtgtcat attaaaggca ccagtcagat tgaccttgag cactttttca
    16321 aaatctgctt ctgtcatctt gagcataaga gtatcttggg taatccctgc attgttgacc
    16381 aaaacatcta ctgaacccag ttctgcaata gcttgatcaa tcatacgctt agcgtctgca
    16441 aaatctgata catctcctga aatgggaacc accttgatac catagtttga aaactcagcg
    16501 agcaattctt ctgagattgc cccacgactg tttaagacaa tgttggctcc tgcttgagca
    16561 aacttgtggg cgatggcaag accaattcca cgactcgaac ctgtaataaa gatattttta
    16621 tgttctagtt tcattttttt cctttcaaaa cttctactta ttttagtcta tttttctaaa
    16681 agtgctacta aactcgcttg atcttccaca tgagctaagt gagcagtttg atcaattttt
    16741 ttaacaaaac ctgacaagac tttccccggt ccaatctcga taaagttgct tatgcctgct
    16801 tcttgcatga ccccaatact ttcatagaaa cgaacgggtt ccttgacctg acgcgtcaag
    16861 agctgagcaa tgtcctcttt ttgcatcaca gcagcttctg tattgccgac taggggacaa
    16921 gtaaaatctg aaaaacttac ctgagctaga gtttcagcta gtttctggct agctggctca
    16981 aggagagcgg tgtgaaaggg acctgacacc ttaagaggaa tcaagcgttt ggcacctgct
    17041 tcttgcaaaa gttcaaccgc tcgatcaact gcaaccactt ctccagcaat gacgatttgt
    17101 gcaggtgtgt tatagttggc tggagtaacc actccaagtt cagaagcttt ttgacaggct
    17161 tcttcaatga cctctactgg cgtattgaga actgctacca tcttgccaga gtcagcagga
    17221 gtcgcttctt ccatataggc tccacgctta gctaccaagg caaccgcatc ttcaaaatcc
    17281 aaggcgccgc ttgccaccaa ggcagagtat tctccaagag acaaaccagc aaccatatca
    17341 ggctgatagc ccttttcttg caataaacgg tagatagcaa ccgaagtcgc tagaatggct
    17401 ggttgcgtat agcgggtctg attgagtttg tcctcttccg tatcgatgag ataacgcaaa
    17461 tcataaccga gcacctgact cgctcgatca atcgtttctt taacaatcgg atactgatca
    17521 tagaaatccc gtcccatccc tagatactgg gcaccttgac cagcaaataa aaaggctgtt
    17581 ttagtcattt cttacaactc ctgtccagcg agaggcttct tcttgaattt tcttagcggc
    17641 tccgtaatac aaatctttta ggatttcttc agctgtttct tctttagaaa caagccctgc
    17701 gatttgacct gccatgacag agccaccatc cacatcaccg tgaacaactg ctttggctag
    17761 ggcacctgct cccatttgtt caaagatttc taaatcagga tcttcctgct taaaggcatc
    17821 tttttcagcc agttcaaaat ctctagtcaa ctgattttta atagcacgaa cagcatgacc
    17881 aaagtgctga gctgaaatcg tagtgtcaat atcccttgct tttaaaattt tctccttgta
    17941 gtttggatgg gcattcgact cttttgcaac tacaaaccgt gtccccacct gtacagcctc
    18001 tgcacctagc ataaagccag ccgcagcacc ttcaccatcc gcaattcctc ctgcagcaat
    18061 aacaggaata gatatagctg tggctacctg tcgcaccaag gtcatggttg ttaatttacc
    18121 gatatgcccc ccagcttcca ttccttctgc aataacagcg tctgcaccga ttttttccat
    18181 gcgtttagct aaagcgacac taggaacaac aggaataacg attatcccag cttcatggaa
    18241 acgttccata tacttgcttg gatttcctgc tcctgttgtg acaactttaa caccttcttc
    18301 aataacgaga tccacgatat cttccacaaa gggagataag agcatgatgt tgaccccaaa
    18361 gggtttatca gtcaatgatt tgattttatc aatattggcc ttgacaactt ctttcggggc
    18421 atttccccca ccgataattc ctaatcctcc agccttggaa acagcccctg ccaaatcacc
    18481 atcagcaacc caggccatcc ctccttggaa aataggataa tcaatcttca ataattctgt
    18541 aatacgcgtt ttcatagtgc ctccaacctt ccttgcttac gtaatagttc gatttcacca
    18601 taatttgaca gtcaaactat tacctaaaca agagggagtg ggtttctccc tactccttct
    18661 actaatattc tgcttatttt gcttgctctt caacgtaagc aaccaagtca ccaactgttt
    18721 tcaagtcatt ttctgcttcg atttggatat caaaagcatc ttcgatttct gagattactt
    18781 ggaacaagtc caatgaatct gcgtccaaat catcaaaagt tgattcaagt gttacttctg
    18841 atgcgtcttt tccaagttct tcaacgataa tttcttgtac tttttcaaat actgccatga
    18901 taggactcct ttaaaataaa tagttttttt ataacaatgt gttcaccaca tgattaccta
    18961 aattgtaaga atgagcgtgc cccaggtcaa gcctccaccg aagcctgata gaagaacagt
    19021 ctggctacca tctaaaggga tgagaccttg ttctacacac tctgaaagta aaatcgggat
    19081 actggctgca ctggtattgc catattccat catattggct ggaagtttgg ctcggtcaac
    19141 accaattttt ctagccatct tatccaaaat acggtcattg gcttgatgaa gtagcagata
    19201 atccaagtct gtcacctcta taggagattc atcaatagtc tgcttgatag acttggctac
    19261 atctcgaatg gcaaaatcaa agactgtgcg tccatccatc ttcaaaaatg aatctgcact
    19321 ttcttgatct gaaaatggag aatgcaaacc tgaatgccca taagttaaac actcgctgcg
    19381 acttccatcg ctattgagac tctcagctaa gaaatgctct tgctcgctag cttctaacaa
    19441 gacaccacca gcaccatctc caaacaacac agctgttgat cgatccgacc aatcgactgc
    19501 cttagagagg gtttcactac caatcaccaa gcctttttga aagcgaccag aagcgataaa
    19561 cttttcagca gttgaaagag caaatacaaa tccactgcaa gccgcggtta agtcaaaagc
    19621 aaaggcttta ttagcgccaa tattagcttg aacacgagca gctgtagagg gcatcatcga
    19681 atctggagta atggtagcta ggatgataaa atccagttct tctcctgtta ttccagcttt
    19741 tgccatcagt ttcttagcaa cctctgtagc caaatcactg gtagattctg ttcttgaaat
    19801 atgcctttgt cgtattcccg ttcgacttga aatccactca tcattggtat ccataatctg
    19861 agccaagtcg tgatttgtaa ccacttgctc tggcacataa tgagcaacct gacttatttt
    19921 tgcaaaagcc attatttcaa atcctccaaa aattggtaaa gattagtcaa gcctttaccc
    19981 atgacagcaa tttcttcctc gctcatgcca tcaataattt tttctaccat ggccttgtgg
    20041 aagcgtttat gcagtctatg aatcaagcga cccttctttg tcaaatgcag atgcaccaca
    20101 cgacgatcct gttctgaccg aactcgctca atgtagccct tacgctctaa attgttcaaa
    20161 cttgtcgtaa cagttccaag agttaccatc aactcttttg acacttgact tggagtcaca
    20221 tctggagcct taccgatgac atcaatcgta tgcatttctt tgatggagat atccttaaaa
    20281 cgactacctc tcaagttcac ttcctcaatt acaaggacat tgttaaatat agatgttaaa
    20341 tattcattga ttcgttggta gtccattttt catatccctc cttcttcaaa aaacttttac
    20401 aatcaaaaca tttgacagaa agaattatat caaaattcaa agaatgatgc aaggattttt
    20461 tattttcctg taaatttagg tcttcttctc tccgaatgag ctcgcactcc ttctttgaaa
    20521 tcctctgttt gagctaagga tttctgtagg ttcagttcta aagtagcgta accctgccag
    20581 tctttaaatt ggctctccca aaccaacttc ttaatggcag cataggaatt acttgaagca
    20641 cgtcttaatt ttttaagaag ctgttctctc gtcttttcaa gtttttcagc ttcagaaacg
    20701 cggtaaacca acccccattc tagggctttt tctgccgtta aagcctctcc tgtcatagct
    20761 aattgagcag cacgcgtcac accgatactg cggctcaaga gatgaattcc ccctgcatct
    20821 ggagccaaac caacaccaac aaaggcttgg ataaacttag ccttatccgt cgccaaacag
    20881 aaatctgccg caacagccat attcgctgcg gcacctgcaa cagcaccgtc aacttccatt
    20941 aaaacaggtt tggctatttg cttgatttta taagaaatcg tattgaccaa ctctgcgatt
    21001 tttgtcaatg atggaatatc atcctcatcc actgcccgct tcatctctac caaatctccc
    21061 ccaactgaga agacctttcc attggcattg attaagataa aatgcacagc tggattttct
    21121 tctgccaaag tcagagcttc taaaatctcc tcacacatgg gaatatgaaa accatttgcg
    21181 acctcaggac ggttcaaggt aaggattgcc aagtcctctt caagctgata aataatgtgt
    21241 tccatcaggg ctccttttta ttttataagc agtttatact cttcgaaaat ctcttcaaac
    21301 cgcgtcagct tccatctgca acctcaaaac agtattttga gctgacttcg tctagcttct
    21361 tagtttgctc tttgattttt attgagtgtt aaattatttc actgtcaaag tatatctttt
    21421 ttaggatcag aaagcaagaa aaaatcgact gaaagtgtct cagccgataa gaaaggctcg
    21481 ctttaggcta gaaagcatct tattttcttc attgaaaaaa gcctttcttt ctgctataat
    21541 cgtataaaat acttacttta ggagttctta tgaaagttgt taaatttgga ggtagttctc
    21601 ttgcctctgc tagtcaatta gaaaaagttt taaacatcgt caaaagcgat tcagagcgtc
    21661 gttttgtagt cgtttctgcg cctggtaaac gcaatgctga agatactaag gttacggatg
    21721 ccctgattaa atactaccgc gactatgttg cgggtaacga tattagcaag agccaaagct
    21781 ggattatcga ccgctatgct gctatggtta gtgaattggg actaaaacca gctgtgctag
    21841 aaaaaatttc taaaagcatt cacgccttgg ccactcttcc tattgaagaa aatgaatttc
    21901 tctacgatac tttcctagca gccggtgaaa ataacaatgc caaattgatt gctgcctact
    21961 ttaaccaaaa tggtatcgat gcacgctata tgcaccctag agaagctggg attgtggtca
    22021 caagtgaacc tggtcacgct cgcatcattc catcaagtta tgacaagatt gaagaattga
    22081 caaacaccaa tgaagtcctt gtcattcctg gtttctttgg tgtcactaag gaaaatcaaa
    22141 tctgtacttt ctcacgtgga ggatctgata ttacaggttc tatcattgct gctggtgtca
    22201 aagccgacct ctatgaaaac tttacggacg ttgatggtat ctttgcagcc caccctggta
    22261 ttatccacca accacactcg attcctgagt tgacctaccg tgaaatgcgc gagttggcct
    22321 atgcaggctt ctcagtcctt catgacgagg ctcttcttcc tgcctaccgt ggaaaaattc
    22381 ctctggttat caagaatacc aacaaccctg accatccagg tactcgtatc gttctaaaac
    22441 acagtaatga tgaatttcca gttgtgggaa ttgctggtga ctcaggcttt gtcagcatta
    22501 acatgtcgaa atacctcatg aaccgtgagg ttggatttgg ccgcaaggtt ctgcaaatcc
    22561 tggaagaact taacatcggt tgggaacata tgccaacagg tatcgacgat ctttctatca
    22621 ttctccgttc tcgccaacta actcccatca aggaagaaga aatcctgcgt cagttggttc
    22681 aaaaggctaa agtagatcat gcagaaatcg aacacgacct ttctatcatt atgattgttg
    22741 gtgaaaaaat gaagagccac atcggagtga ctgctactgc gacacgcgct ctatctgaaa
    22801 acaaaatcaa catccagatg atgtctcaag gttctagtga agtttctatt atgtttgttg
    22861 tcaataaaga ccaagagaaa gcagcaatta aagccctcta caatgccttt tttggagaaa
    22921 gtaaggaaga ctaagcatgg cccaatcact taacaaaaca gtactcctca gtacgacagg
    22981 cacttcctac ctctctatcg ctgggaaagt tgggaaattc cttgtcggag atcaggcttt
    23041 ggaattttac ccagatgtca atgtcgaaca atttatccag attccttgga gccatatcaa
    23101 tcagattgga gccaatgtca ctggacgcaa aatcagccgc cacttcgaag tctttacaga
    23161 caaaggaaaa ttcctctttg cttcaaaaga ctcaggtgcc attctcaaaa ttgcacgcga
    23221 aaaactaggc aatgacaagg tcgtcaaact tccgaccctg attcagacaa ttagccaaaa
    23281 atttaaaaat ctatttgcaa aaaagtagaa actttagtat aatcatagca acggataagt
    23341 aggttatctt cttctttcag aaagtctgcg ggtgctgcga gcagatagga gggataggtg
    23401 aaattctacc gttagtgaca attacataca caatcaagtg cacacctgtg aagttggatg
    23461 gaaccgtggc cctgccactc caacgttttg tcagggtgct tttttcataa aggagttctt
    23521 atgttagata tcaaacgtat tcgtacagat tttgaagctg tcgcagaaaa attagctaca
    23581 cgtggtgtag atgctgctgt cttgaatgaa atgaaagaaa tcgatgctaa acgtcgtaac
    23641 atcttggtca aggttgaaac tctcaaagca gaacgtaaca cagtttctgc tgagattgcc
    23701 caagctaagc gcaacaagga aaatacagat gacaagattg ctgccatgca aaatctatct
    23761 gctgaggtta aagccttgga tgctgaattg gcagaaatcg atgctaaatt gacagaattt
    23821 acaacgactc ttccaaatat cccagctgac agcgttcctg ttggggctga cgaagacgac
    23881 aatgtggaag ttcgccgttg gggtactcca cgcgagtttg acttcgaacc taaagctcac
    23941 tgggatctcg gtgaagacct tggtatcctt gactgggaac gcggtggtaa ggtaacaggc
    24001 gctcgcttcc tcttctataa aggcctcggt gctcgtttgg aacgtgctat ctacaacttt
    24061 atgttggatg aacatggaaa agaaggctat actgaagtca tcacacctta catagtcaac
    24121 catgattcta tgtttggtac tggtcagtat ccaaaattta aggaagatac ttttgaactc
    24181 agcgatacca actttgtctt gattccaact gctgaagttc ctctgacaaa ctactaccgt
    24241 gatgaaatct tagacggcaa agatcttcca atctacttca ctgctatgag tccgtcattc
    24301 cgttctgagg ctggttctgc cggtcgtgat acgcgtggct tgatccgttt gcaccaattc
    24361 cacaaggttg aaatggtcaa atttgccaaa ccagaagaat cttacgaaga attggaaaaa
    24421 atgacagcca acgctgaaaa cattcttcaa aaactcaacc ttccataccg tgtcgttgct
    24481 ctctctactg gagatatggg cttctcagct acgaagactt acgacttgga agtgtggatt
    24541 ccagcacaaa acaattaccg tgaaatctca agctgttcaa acacagaaga tttccaagcc
    24601 cgtcgtgccc aaatccgtta ccgtgatgaa gcagatggca aggtgaaact ccttcatacc
    24661 ttgaacggtt ctggacttgc agttggacgt acagtggctg caattcttga aaattaccaa
    24721 aatgaagatg gttctgtgac catcccagaa gcacttcgtc catacatggg tggagctgaa
    24781 gtcatcaaac cataaaaaat aaggtttagc tatttctagc tagacctttt ttcgtaacca
    24841 aatcagataa gcacctagta caaagaataa aatagttagg catataatgg tttcagtcaa
    24901 taccaggtaa tccagaaatg gaagtttcaa aattccctga gccatcttga gcgaggtcgc
    24961 tgtgataatg gttgggaagg tgagggctga gaaggctggt tgaaaacctt gttttaaaat
    25021 gttgggcaga cgagttaaaa caaagaaaaa gaaggattga gaagccaaaa tcatgacaat
    25081 caagacccaa gtcggcaggc tggttcctcc tactcgaact agagaagcca agagtagaga
    25141 gaaaggagca cagtagattc cttcttgtcc aagcaaggct agtgggagtg gatgtttctt
    25201 taaatcgcta taaataaggg gatagagata gaaggtcaag agaaaaccaa aactcaaggt
    25261 cgcataggca atttcgataa tacctaccag aggataggtc aaggcagcca ctgctatccc
    25321 cacatagaga accgtccaac ttggagtggc atgaaccctc cgccctggac aagcaaactt
    25381 gatggtaaaa ccagcaatca aggtcaaatc caagagaaat gaaaaccacc aaatcccttg
    25441 tgctaccaaa ggaagataag agaatacgcg aaagacatag gtcgataaaa tcatcccagc
    25501 cataggaaag gttgccattc ctgacaaaag agggggcttg gtcaattctt gcttggtttc
    25561 tttccaatta aagagatgca gaattagaaa gtaaatccat aaaaccaaac cagtcagact
    25621 aaaaagatgg gatagaaccg gcaacgtatc taaaataaga tttccagctc ctgccaaacc
    25681 tagcaaacaa cctgaaaata ctaaggggag ttttttcatc ctaacctcca ataatcatgt
    25741 tagtttcagt ataacataaa agcgcttaaa tgaggattta aaaaaacgaa gtccgcttat
    25801 ttcagacttc attttactca gatatgaatt aggcataagg ttgcaattct ggattaattg
    25861 gtgtattagc taagttgttg gcatagttac agaggattgc taggctgaca ccaaaaacca
    25921 catccaaggc attttgttga gtgtagccag cttctaaaaa ctcagacaag gcttcatctc
    25981 ctacacgacc cttggtattg ataactgcca aggtaaactt agctagggta tccaatttag
    26041 gatctgtttc aattggagta cgattgcgaa gagcttgaat caagtcatca ttcatctgga
    26101 tttgtttgat ggaaaaggct gtgtgacctg cgacacagaa ggcacaacca ttggtcacgg
    26161 ctgccgtgat ttgcaccact tcacgctcaa cgggtgtcag gctgttgcga cggtggatag
    26221 atgagacaat ttgataggct tctaaaacag tcggggcatt ggccaagaga ccgattaggt
    26281 tgggaatata gccattgttg tctttttcta ctgtttcaag aatttctttc acttctgctg
    26341 gtgctgactc tactgtatgg atagtaaatg ttgtcataag atacctcttt tcttattatt
    26401 gacactaata ttattggaaa atcttataaa atcctgattc ctaagtttat ctaagataaa
    26461 gctttattct ctcataagat tttcgttgtt atattagttt atcacacttc caatcacttg
    26521 cataatatat attatatatc aggctgataa aaattattta taggcaaaaa aatcacacga
    26581 gctgtgtgat tccattattt gtcaaaatac tttttagttt cagcaataac gactggcgac
    26641 aagaccaaga gggcaatcaa gtttggcaga gccatcaagg cgttaacgat atctgcgata
    26701 atccagacca tatccaactc gataaatcct cctaacaaga ccatgagcac aaaaaccaca
    26761 cggtagagcc agataaagcg aaccccaaag aggaactcaa aacagcgttc tccgtaatag
    26821 ttccaaccta gaatcgttgt aaaggcaaaa agtacaagga agatggtcaa gagggcaggc
    26881 ccaaagtgtg aaaagactgt tgagaaagct gactgagtca aggcaacccc attcaagtca
    26941 ccactccaaa ctccagttac caagatggtc aaaccagtta gagtacaaat gatgagggta
    27001 tcaataaagg ttcctgtcat ggaaatcaaa ccttgctcta ctggttcatt tgtcttggca
    27061 gctgcagctg caataggagc agaacccaga ccagattcgt ttgagaacac accacgcgcc
    27121 acaccatttt gaatagccat ccgaacgcta gcaccagcaa atccacctac cgcagcaagg
    27181 ggactaaaag ctgaggtaaa gactaaagcg attgtgccag ggatttttcc gatattaaag
    27241 aaaataactg taagagttcc taagatataa atgatggcca taaaaggaac aacagtagtt
    27301 gaaaccttag aaatagactt gagtccacca aagactgcaa tcgctacaaa gacagacaag
    27361 acgagagctg tgatggctgg cgaaatcgtc gttgtatttt ggatagattc tgcaatcgag
    27421 ttgacttggg tgaaggttcc gattcccaag agagcaacca atactcctgc tactgcaaac
    27481 aaaacagcaa gtggtcgcca cttttctccc atccctagaa ggatataatg catgggacct
    27541 cccgctactg caccatggtc gtccttggtg cggtatttga tggccaagag tccttccgca
    27601 tacttggtag ccattccaaa gaaagccgcc atccacatcc aaaatagagc tcctggtcca
    27661 ccaaccttga tagccgtcgc aactcctatg atatttcctg ttccaacagt tgatgccaag
    27721 gctgtacaca gagctgcaaa actggataca tcaccatgtc ccttatcctg gataaaaata
    27781 agctgaaaag ccttgggcag acgcaaaacc tgcaagagtc ctagccgaat agttaggtaa
    27841 atccctgttc cgaccaataa aatcaagagg ggcggtcccc aagcaaaagc atcgattgat
    27901 ttaagcaatt ctaacatttc cttctcctat cgtttcaacc ccaaaagaaa gagcacatgc
    27961 aagatacatg tactctggaa tgcttagata aatgctaaaa agcggtctat cctagctctg
    28021 tccttttacc tgagagtttg agcagttgcc tgccttgccc cttcggtgcc tttacggtct
    28081 ctccagagtt ccgtccattt acagtcatgg aaaatcaaac gattccccac ttctattaaa
    28141 cttcattcgg tgttggtatt taattgattc taattttaca aaaaatgttg gcttttgtca
    28201 atgtgtttat tagtaaaaat tagttcaaca gtttttactt tataaagtcc agaatactgc
    28261 tatcctttaa aagtgacaat agtcgcacca ctgcctccag cattttgtgg ggcatagccg
    28321 aaactcttga catgtttgtt tctttgcaag tatttggtaa ctccttcacg gatgactcct
    28381 gttccgatac catggatgat atcaacttga gccatattgt taagcaaggc ttggtcgatg
    28441 aaggtatcta gctcattcat ggcttcttca tagcgcttgc ctcgaagatc cagtctagct
    28501 tgaggtcctc gcccagaagt tcgtttcaca acattgacct gtttcttctt gactggtttt
    28561 tcttgctggg cttgaacaag atcaaactct ttctcttcca aggtcatctt aatcaagcca
    28621 acttgggctt cccagcggcc gtccttgagt tgactggtca aggtaccacg ctgaccataa
    28681 ctgagaacca cgatatcatc tcccaccttt ggagctcgtt ttttcttggc cttttgaagg
    28741 accttgtttt tagacaagtc cactttttca ggagccaatt ttttcaactt ggccttggct
    28801 tcaatgattt cgtggggctt gagttgggat ttactgtgga gatttttgag aatctggtca
    28861 ctttcactta gggccatatc cacaatctca gcagcctgtt cacgcgcctt gttaagctcg
    28921 gtttcctttt cacgattaag ctcgttgtag agttttttta gcgcacggtt catcttgaga
    28981 ttttcttgct ccacctcacg gatattgtcc aagcgtttgc ggctttccag cgtctgctct
    29041 tctaattgct caatgatacg attgacgtca ttgtcctgat cgatctgctg actggcatct
    29101 cctacgataa cttcagatag gcctagacgt ttggcaattt caaaggcatt acttcggcca
    29161 ggaacaccct gcataaagcg ataggtcggg cgaagagttg cagtatcaaa ctccatactg
    29221 gcattttgca caaaggctgt ctcaataccg taggccttga gttctggata gtgggtcgtc
    29281 gccatggtct tgatttgacg caggcgaagg tcctccagaa tagccatggc aagggctgct
    29341 ccctcttggg gatcagtacc agcccccaac tcatccaaaa gtaagagtga atgttggttg
    29401 accttgccaa gaatatccac gatattggtc atatggctag agaaggtaga caagctctgc
    29461 tcaatagact gctcatctcc aatatcagca aagatttctt caaaaatacc aacacgactt
    29521 cccttgtctg ctaaaatcgg caatcctgac tgggccatga cctgtgtcaa gcccagagtt
    29581 ttgagcatga tggtcttccc acctgtattg ggacctgtaa tgacaatagc tgttaaatct
    29641 tgaccaaaat agacatcatt tgcgacggca tttttgacca aaggatggca gacatggagc
    29701 agttgaatct cttgattttc tgacagctga ggcacgactg cttgtctttc ttggataaat
    29761 cgaaccttgg cacgaatcaa gtccagatga ccgataatcc aagcgtcatt agcaatctca
    29821 gccgcatgag ggcggacacg ctcagaaatt tcttggagaa tgcgaagcat ttcatagcgc
    29881 tcatctgctc gcagactagc aatttcttcg ctcagtttga ctacctcacg tggttcgata
    29941 tagacggtgt ttccactagc agaaatatca tgaacgacac ctgcaatctt attgcggtag
    30001 gtgtttttga ctggtaaaac ctgacggcca tttctgctag caacaattcc ttccgtcaac
    30061 atctgcgctt tttgcttgag taagtcttgt aaaacatcgc gcacctgact ctcgctatca
    30121 tgtatttttc gacggattcg cgccaattct tcactggcaa aattttcaat gaaacccgca
    30181 tcattaaagg cctgaagatt tccttgtaat tgcggaaaat catgtaattt ctcaaaccaa
    30241 agggctaatt cttccaagct gacattttcc agattggcgt aaaaattttg aagttctcgg
    30301 ctggcaagaa gcacgcgttt caagagtagg aactcctcga tattgagatc cgctcccatc
    30361 tccaacctct tgcagactcc tgcaatttcc ttagttgaga gaatagtaaa atgcggttgc
    30421 tcgacgaaaa gagcctgcat ttccttcatc tcagcaaaag cctgtttgat tttatctgct
    30481 ttggcagtcg gagccagctg tatcaattgc tccaagccct gctcggtcaa caaatgaggc
    30541 tcaaacaagg ccttgacctt atcgaactct aatgtttcta atattttctt attcatcttt
    30601 atttccttgt ctttgaatgt ctaggtgtgg tagcttttta cattctgata gattcgagtc
    30661 aaatctgtaa acaaagggct aggaaaactc ctgccctttt tatccgatta aatttgtcac
    30721 ccagatttgt ttgagccaac tggttgttat cggtatgctc tggatgatgt gttttgcgac
    30781 gatactcttt tcaagaggat tttgtataac tgccatgggg atggtcgcca agattgtcaa
    30841 ggccatttgc aagacaaata aggtcaccaa catggacaag atacctgctg aaacttggaa
    30901 caacttacca cccagttttt tgctaggaat caagtgtaag agaagaccaa gcaaacgacc
    30961 aatgctatag acaatcccaa atacaagcaa gtagccgata cctgcataaa agaccttatc
    31021 cagctgaaag agttgatccg atgggaaaaa gaaagtcccc tgaccttcct gcgaatttgc
    31081 ataagggagc aataaatgga attgctctcc aagcccctta taaaactggc cagccataaa
    31141 agccgatgcc atggctgaaa tcaggtaata aacctgtaag agcaggcctc tccgatagcc
    31201 gatataaaat ccccaaacca agaccaatag aagaaggagt gaaatcataa ggaatcctca
    31261 atcttgctct gttcttgctt acaagtcaca agcttgtgac ggagttcttc tagctcttgc
    31321 tccttatcgt caaattcaat ctcacggctg agctgagttg ataaacagtt gactgccaac
    31381 aaaagagcga ttgtttcatc atctgcgcta ggcatttgtt ctttaattgc ttggtatttt
    31441 tctgtcgcaa ccttagcgat ttcctccata aaaaggttat catgttcgct tgtcaaggtt
    31501 aacgattttt tcccgaatgt aaatttgaat cgatttagat ttgccataaa attcacctca
    31561 cgatattata ccaaaattcg ctaattttgt cagtttttac aaattttact gcttttgtgg
    31621 tacaatagaa actatggcaa gtatcacact cacaccaagc gaaaaggata ttcaggcttt
    31681 tcttgaacac tatcaaacca gtctggctcc tagcaagaat ccctatatcc gctacttttt
    31741 gaaactacct caagcaacgg tttctatcta tacttctgga aaaatcttgc ttcagggtga
    31801 aggggctgaa aaatacgcca gtttctttgg ctatcaagct gtagagcaaa ccagcggaca
    31861 aaatcttcct ttaattggga cagatgaggt gggaaatggt tcctactttg gtgggcttgc
    31921 agttgtggct gcctttgtca cacctgacca gcacgacttt ttacgaaaac tcggtgtggg
    31981 agattctaag actctgaccg accaaaagat tcgtcagatt gctcctactc tcaaggaaaa
    32041 aatccagcac caggcactcc ttctctcacc cagcaagtac aacgaggtca tcggagaccg
    32101 ctacaatgct gtttcggtta aggttgccct ccataatcag gctatctatc tcctccttca
    32161 aaaaggtgtt cagcctgaga aaattgtgat tgatgccttt accagtgcta aaaattatga
    32221 caagtacttg gcacaagagg ccaatcgttt cagcaatcct atcagcttag aagaaaaggc
    32281 tgagggcaaa tacttgtctg tcgcagtttc ttctgtcatt gcgcgtgatc tctttctgga
    32341 aaatcttgaa aatctgggac gagaactggg ttatcagctt ccaagtggag ctggaacggc
    32401 ttctgacaag gtggctagcc agattttgca agcctatggt atgcagggac tcaatttctg
    32461 cgtcaaattg cactttaaaa acactgaaaa agcgaaaaaa cgcttagaaa ggtaagttat
    32521 gaattcattt aaaaatttct taaaagagtg gggactgttc ctcctaattc tgtcattact
    32581 agctttaagt cgtatctttt tttggagcaa tgttcgcgta gaaggacatt ccatggatcc
    32641 gaccctagcg gatggcgaaa ttctcttcgt tgtaaaacac cttcctattg accgttttga
    32701 tatcgtggtg gcccatgagg aagatggcaa taaggacatc gtcaagcgcg tgattggaat
    32761 gcctggcgac accattcgtt acgaaaatga taaactctac atcaatgaca aagaaacgga
    32821 cgagccttat ctagcagact atatcaaacg cttcaaggat gacaaactcc aaagcactta
    32881 ctcaggcaag ggctttgaag gaaataaagg aactttcttt agaagtatcg ctcaaaaagc
    32941 tcaagccttc acagttgatg tcaactacaa caccaacttt agctttactg ttccagaagg
    33001 agaatacctt ctcctcggag atgaccgctt ggtttcgagc gacagccgcc acgtaggtac
    33061 cttcaaagca aaagatatca caggggaagc taaattccgc ttatggccaa tcacccgtat
    33121 cggaacattt taagaaacct aagaggccga gaatcaccaa tctcagcctc ttcttctatc
    33181 gtgagaaaat gattggtaac tatctaaact taccagaaca gaaacacctc aactctcacc
    33241 tattcatgca aaggaatttt atggaagttt atttttcagg aaccattgaa cggattattt
    33301 ttgaaaatcc cagcaatttt tatcgcatcc tcctcctaga aatcgacgat acggacgcag
    33361 aggattttga tgattttgaa atcattgtca caggaaccat ggctgatgta attgagggcg
    33421 aagactatac tttttggggg caaattgtcc agcactccaa gtatggagaa caactgcaaa
    33481 tcagtcgtta tgatcgcgca aaaccaacta gtaagggctt ggtcaagtac ttttcaagta
    33541 gccatttcaa ggggattggt ctcaagacag ctcagaaaat cgtggatacc tatggcgaaa
    33601 ataccattga cgaaattttg caacacccag aaaagttaga aggcatcgca ggactctctg
    33661 ccaaaaatcg cgaggctttc gtctccactc tccgtctcaa ctacggaacg gagatggttt
    33721 tggccaaact agccaactac ggcattccca acaaactagc ctttcagatt caagactttt
    33781 acaaggaaga aacccttgat gtggttgaaa attatcccta ccagctggtt gaggatatca
    33841 agggtttggg ctttaccatt gctgaccaac tagctgagga actaggcatc gaaagtcagg
    33901 ctcctgaacg cttccgcgcc ggtctagttc acagtctttt tcaggcctgt atggaaacag
    33961 gggacaccta tgttgaagca cgggatttgc tggaacaaac ccttactctc cttgagtctt
    34021 cccgtcccgt ggaactagac cccagccaag ttgcccaaga gctctcctac ctgatcgaag
    34081 aagacaaggt tcagcagatt gataccaaga tctttgacaa cagcctcttt ttcgctgagg
    34141 aaggtatccg cagtcacttg attcgtatcc ttgaaaaagg aaaacagaag agccaagatt
    34201 tagaaactat tcaaaagcat atcactactg tcgagcaaga gctgggaatt gagtatgata
    34261 acattcaaaa acaggctatc tgtgatgcta tccagaataa ggtctttatc ctgacaggtg
    34321 gacctggtac tggtaagaca actgttatca atgggatcat cgctgtttac gccctgttag
    34381 agggacttga cctcaggaag aaaagcaatc tgcccattct tcttgctgct ccaactggac
    34441 gagccgctcg ccgcatgaat gaattgacag gtttgcctag cgcgaccata caccgccact
    34501 tgggaatgac aggtgacgat gataccagtc atctggaaga ttacctagat gctgacttta
    34561 tcatcgtgga tgaattctct atggtagata cttggctggc caatcaactc ttctccaata
    34621 tctcttctaa cagtaagatc ctcatcgtag gtgacagtga tcagctacct tctgtcagtc
    34681 ctggacaggt tctagcggat ctgcttcata ttcctttgat tcctcagact cgcttggaaa
    34741 aaatttatcg acaaagcaaa gaatcaacca tcgtcaccct agctagtcag attcgacagg
    34801 gcatcttgcc agctgatttc acccaaaaaa aagctgaccg ttcctacttt gaaattgcta
    34861 gtggccatat tcctgccacc attgaaaaaa tcttaggtgt cgccctcaga aatggtattc
    34921 ctgcccgtga tatccaagtt ctggctccta tgtaccgagg gacggcaggg attgatgcta
    34981 tcaatcagct catgcaagac ctgctcaatc ccccacaaaa agatcaactc agttttgaag
    35041 ctcctcagtg ccactatcgt aagagagaca aggtcattca tttggttaac gatgctgaaa
    35101 tcaatgtctt taatggggat ttaggagcta tcacagacct gattcctggt aaatacaccg
    35161 aatcgaaaca agacgagatt gtcattgatt ttgatggtaa tgaagtctct tacccccgta
    35221 acgaatggta caagattcgc ttggcctatg ccatgagtat tcataagtct cagggaagtg
    35281 agttcccagt tgtcatccta ccgattacta gtgctagccg acgtatgctg gagcgaaatc
    35341 tcatctacac agccattaca cgtgccaaaa gcaaactcat cttactaggc gaattacaag
    35401 ccttcgacta tgctacccaa cacatcggaa ctgcccgaaa aacctatctg attgaacgct
    35461 tcagtgatct actggagaat gttgaagaaa agcaacaagc tgtctctgaa acagtcacat
    35521 caagtgcctc tgaacaatcc tacatcctaa ccgaagaaaa ctgggacagc attccagcca
    35581 tgattgggat tacagacaca gacctcaaag agatttttgg aaaatagtac atcagaaaac
    35641 ccaccaattc aggtgggttt tctgtttatt aagattattt tactgttgct gtgcttgtga
    35701 tcaattcaac agcttttttg atagtgatat catgtttcaa catgtcagct gaaagcaagt
    35761 tttgaacttg tgcaacttcc atgttgtagt ctgctgccaa ttgctcaact tctttttgga
    35821 tttcttcttc tgaagcatca aatccttcag ctttggcaac tgcttcgata acaaggttag
    35881 tcttagtacg tgactcagct tctgcttggt attggttgtg aaggtcttct tgattagttc
    35941 cagtgatttg gaagtacatg tcagggttga tcccttgacg ttgcaagttc ccaaggaatt
    36001 catttactga acggtgaact tcttcatgga tcatttcttc tggaagttct acgatttcag
    36061 cgttttctac agctgtatca attgctgcac cttcaactgc atctttgtaa gcttcttctt
    36121 tagcagcagc caattctttg cggtattttt ctttcaagtc agcaagtgtt tcaacttctt
    36181 catcaatgtc ttttgcaagt tcatcgtcaa gagctggaac ttctttagct tttacttcgt
    36241 ggatagttgt cacgaattta gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg
    36301 ggaatgttac gataacatca acggtttcgc cagctgagtg acctaccaat tggtcttcga
    36361 aaccagggat gaattgacct gaaccaagtc caagtgagaa gttttcacct tttccaccgt
    36421 caaattcaac accgtcgata gaaccaacga agtcgatcac aacagtgtcg ccgttttcag
    36481 cagcagcttc cttgataacc aattcagcca ggttgttgcg ttcgcgttcg atacgctctt
    36541 caacatcagc gtcagttact tctttttcta catcaactga tacttcaagg tttttgtagt
    36601 cacccaattt tacttcaggt tttgtaacga cttcagcagc gataacccag tcttgacctt
    36661 tttccattga agttacgtca atttttggtt gggcaaccac ttcaagacca gcttctttta
    36721 cagctgcttc ataagcgttt ggcaaaagag cgttcataac gtcttggtaa agtgattctt
    36781 caccaaattt ttggtcgaag ataggacgtg gaaggtgacc tttacggaaa cctggaacat
    36841 taagagattt cttcactgac ttgaagacac ggtccaattc tggtttgatt tggtcttgag
    36901 agatagtgaa agtcaagaca ccacggtttg tttctttgtt ttcaaatgat acagacattc
    36961 tgtcatttct ccttaaaatt ttttaaatac agtctattat aacattttct ataaataaaa
    37021 tctagactaa tgcagccaat tatagacaac aagccttttt cctaactaaa acactcataa
    37081 agtatagaca attttagact actttggata tcttttggtt agtcattttc caaaactaat
    37141 ttatctaatt tttcagttat atttgacttc atcttctcag taacatgagt ataaacactt
    37201 aaaatctttg tttcattagt ataatctaca cgatccatta tcgctgttat aggtacttcc
    37261 aattcagcaa gcaaacttat atgcgaatat ctaaaaacat gagcagtcaa tacaaaatca
    37321 tctttcttaa tttcactttt cctaaaactg tttttcaaaa agtaattgaa acaagttatc
    37381 attaagggag aaccattatt tgtaaatata taatcacctt cttctaaaag aagatattct
    37441 tttaaaattt ctaacactct atcactaata ccaattactc tatatgaagc taaacttttc
    37501 ggactatcca aaaatacttc gttattggac gattacatta tagtaaaacg aaataagaac
    37561 aggacaaatc gatcaggaca gtcaaatcaa tttctaacaa tgttttagaa gtagaggtgt
    37621 actattatag tttcaatcta ctatacaaga cgaaattgaa gaaatctttc cattataaaa
    37681 cgcatattat caaggttttt aaacacctaa taatatgcgt tttttcctat tttaaagact
    37741 tttatccacc tattatacaa agtcaagtat ccatcacagt ttacaattag tcttcattac
    37801 ttaacccatt caccattata gtttaagtag taaccaccta ctgtggtatt aacagctaaa
    37861 gcacctgaat cataggtata gtaccagtta ccattgactt ggaaccagcc tgttttcata
    37921 tctccattac ttgcatttag atagtaccaa gtcgaacctt cctgatacca accagttgcc
    37981 atagctcctg atgaacggag atagtaccac ttgttaccaa ggtattgcca gccagttctc
    38041 atatcaccat tttcagcatc taaatagtac caagttgaac catcttgata ccagccagtt
    38101 gccatagctc ctgacgaatg gaggtagtac catctattac ctagaaattg ccaaccagtt
    38161 tgcataatgc cagttgttgg atctagatag taccatggag ctgcttttag cttctcttca
    38221 tcataggtaa gagggtaatc cttaacccaa ccacgtgcta gctctccaac cgtcaatctg
    38281 ttgatgcgcg aatcaaagcc accatccttc tgtaaataat accaatgacc ctcttcataa
    38341 atccaaccag tttttaaagt atgataacta cgctgatctt caaaataata gactcgtttc
    38401 tctgctgggc tatcatattc ttccccatga tgtttgttgg tattcgtagc agtttttgct
    38461 tctaaaactt gcttgccaac aaattcttgt aagacaccat cttgaccaaa ataaaaccaa
    38521 tctggtctaa gagcaatctc tattcttgga gaaggaccaa tcgtaacccc cttgtgtgga
    38581 gcaggtatat attgccagcc gacaaccatc tctccggata aaggatcaaa ataatagtac
    38641 ttcccatcta tcactctcca gtaggtttct tttagatccc cctttttgta gtaggttcta
    38701 ccattttctt ggacaaactg ccatccttca gaatcatctg caaatactgt actggtccct
    38761 agcaaaccga agaaaaatgt ggctagtgcg acttgcatca tttttttcaa aagcttcatt
    38821 ttatatatcc tccaacatta aatccactca ccagatgaag cgaagttata aactttacca
    38881 tcgatagttt ggctacctgt aaccattgct ccatttgaat tgagataata ccattttcca
    38941 tttacttttt gccaatctgt aagcatctta ccggaactgt ctaaataata ccaagtatca
    39001 tttatctcct gccaacccgt ttgtttatca tgttgtctat aatggtacca actaccattt
    39061 attttcttcc atccttcaag agagtaacct ttaagaaccg aataaataaa tggcaaattt
    39121 cgttcattta atttaactgc actgttaatt tgattagctc catctcctaa agtatgcact
    39181 cctactacgc ggtgactagc atcataaact gtagatccac tagacccctc taaagtatca
    39241 acttggtaat ccaagaacat gccatcatca cttaaaactt gttttttatc tgtatacatt
    39301 tgatgaattt taaaattata tgatggatag cctgtgatag tcacagttat tcctgtcaaa
    39361 tttttttgat tagtaggaag acccaaagtc cctaattttg caccaatggg ctcttctaga
    39421 attaataaag ccaagtcata ttcccttgca tccttagaat ttaaatttct aaattccttc
    39481 aaataacgaa cttcctttac tttgatcttt ccaaatggtt cttgacttgg actaacagcc
    39541 ggaagaacat aaatatcatc cgcttctttc ccatagtcat gtctgtagta gttgtgagcc
    39601 gctgtaatta acacattatc tttaataaaa ttcgcacttc ccctcccttc tacattcatt
    39661 ccatcggcta ctccataata cttagataaa accatagctg aagtcgaata cggatactgt
    39721 aaagtattat caattttaat caaatcatca ttactgataa tacttctgat tgcttttggt
    39781 agtatgaacc atacgttggt gaaatctcag ataatgaaga atcattagac cctggacctt
    39841 tttctagtgt ctcacttacc tcatattctt cacctgtatt agaaataaca ctcaaagcag
    39901 atactgtcga taactggcta gccaataaag tactcgcaat aattgaaata cccaattttt
    39961 tataaacagt tttcttcatt attgtatcct cctaatgtaa ttatagcgta ctattctaaa
    40021 tttctcaatc tactatagat tcaagaaatc taccaccttc tttaaatacc ctccattatc
    40081 acataaacag gtaaactttt caattaatga ctgcgctttt caatcacgct agaggtactt
    40141 gcttgcttct ttgatactaa gttcagccat tctttcctta tttttctcaa taaagcatgt
    40201 tacccaagtg ggattcgttt tggagtagtc tcgcagagtc cagccaatgg ctttattgat
    40261 aaaaaattct gtttggttca agttatgaag gagaatcttt tccattaatt gagtattggt
    40321 cttctctttt cttaacaact ggtggttaat agcgacacgt ctcagccaga tattatctga
    40381 taggctccat tttatactca atgaaaatca aagagcaaac taggaagcta gccgcagatt
    40441 gctcaaaaca ctgttttaag gttgcagata gagctgacgt ggtttgaaga gattttcgaa
    40501 gagtattaag attatttctt ctagctcagg gtgttcatac accaaactcc ctactactcg
    40561 atctaggata tctaccgtgt cccaccagga ttttgtcacg actaactgct ctagcttagg
    40621 caaatcggtt tcctttagat aagactgcat tgctttcaaa tagttagcag ccacatattg
    40681 gtattttcta ggctcctttt cccagcaagt gtctgcaaaa tcccaatcga taatctttgt
    40741 ttttttcgct tctggaaaat atttttatag agtttatttc tttcaaccta gaaaagaaaa
    40801 ttgatggcac atataggctt ccatgggcct tgctttttta gagtcttttg ctgcttctag
    40861 ctcctcaagt aaatctgcta aactcatcta aaactcctca tgcccgacca aatggtgctg
    40921 aaaggcatag acagccgcct gggtacgatc gctaacttca agtttggcaa gaatgttgga
    40981 cacgtgggtc ttgaccgtct tgagagagat aaagaggtca tctgcgatgc gctgattttc
    41041 gtagcccttg gcgatgagtt ggagaacatc tcgctcacgc gcagtcaatt cttcatgaag
    41101 ttccatatga ttgcggtggt attcaacctt cttgctaacc tcttgctcaa tggccagctc
    41161 gccagcagct accttactga cggcatgaag caattcatct gcactagaag tcttgagcat
    41221 atagcctttg gcaccagcat ctaagactgg catgattttt tcattgtcca aataagaggt
    41281 cacaatcaaa atcttggctt caggccattc tttaaggatc gctaaggtcg cgtcaatccc
    41341 attcatctca ggcatgacaa tatccatgac aatgacatct ggacgcagtt ccaaggccaa
    41401 gtcaatccct tgagacccgt tggacgcctc acccacaact tctacatcgt cttggaggtc
    41461 aaagtagctt ttcaagccca atcggaccat ttcatggtca tctactagta aaattttcat
    41521 ctttactcct ttatcattcc ttatctaaca ggggaatacg gatatcaact gccagccctt
    41581 gcttgggagc tgtcaagagt tgaactgttc cagccatatc ttcaacccgc tccttgatat
    41641 ttcgcagtcc ataactcaag tcgtctaagc tccctaactg gaaaccaatc ccattgtcca
    41701 ccaccttcag ttgcaattca acatctgtct gatagaggta gacatctagg caagatgcct
    41761 gggcatggcg gagggtattg ctaatcaact cttgcaggat acggaagata tgctcctcga
    41821 ttttcttagg caatttcgtc atattctgct tgagactaac cctaagatca ctcttgtcct
    41881 caagctcttt taagagaatc tgaatccctt ctatcaagct cttctgctcc agttcaactg
    41941 gtcgcaaatg caagagcaaa acccgcaaat ccttctgggc tgtttctaaa atagctgtga
    42001 cactctgcaa ctgggtctgc atcttttctc tatccaattt caaagcctgc tgactgatac
    42061 ccgataaaat catgtgggcc gcaaacaact cctgactgac tgtatcgtgc aaatcccgag
    42121 caattcgctt ccgttccttc tcgatgattt cctcttcctg agcaagactc tgattttctg
    42181 ctttttgaag agcctctgtc aaaaggttaa gtttacctga taaggacttg aaactggcat
    42241 ccaaatctgg atctacaacc tgaactactt cttgccctgc caataaacgc ttgagattag
    42301 cctgcatttt tcttagagaa agctcttcga tccctcgcca aaacagggct aagagacagg
    42361 ttatggacat gctgaaaacc aacaataaaa agacaaattt ttctgttttt tcgacatcgt
    42421 gcaaaaagat agaccagtca aaatcaagta tttccagcaa gctgtgggag aaaaaaaaga
    42481 caaacaggaa ggaggtgaga gcaataatga cataggcttg ttttttcatc ctctaaccac
    42541 ctccacatca ccaatcatag tggtcaagaa aatcttgaca ctcttgttac tcttgagata
    42601 gtcttttgtt tcttgatgat agtgttcatt gcggagggct cgcttgggct ggttgaaaaa
    42661 agtcaaatcc ccatagagac agttaacgct gagactgact tccacatcta caggtacgat
    42721 gattttggtc gttcctacta tctttctgag gataatgaca ttgtcatgat tggttaagat
    42781 gaccctctcc agatgaatag tgtccttgcc catgaagcga aagagattga tatcatcgaa
    42841 ttggcaagtc tggtagcttg aaaaatgatg aagatttcca aaccaacgat ttttctcctt
    42901 cttaaccgtc acgacctctt caaaaaccaa attggtctgc tctttttcct ggttcatcat
    42961 cgggtaaaga agaaagaggc tatagataac cgcaacaaaa atagctagaa tcacaaaagg
    43021 attgagcata acgatgaaaa agaagagaat ggttgccgct actaaaagaa gattatttcc
    43081 ctctttacca gtgtagtagc gaatcaaaag caaaaagagg aatagtatca gcagaaaacg
    43141 cgaaaaatgc tctgatacca tcaaaatcag agctcctgtc agaagacagg cttcgataaa
    43201 taaaaagatt ttaaattttc tcataggttc atcctctccc ttctatttta tcacaattca
    43261 aaaaagtcac ctcagtctga ggatggaaaa aaaggcgctg gttacgcctt tttcatctga
    43321 tcatttgctt cttttaattt tccataaaga agatagtcta ctttttgtag atctgctatg
    43381 gtggcacagt taagggaaca cataatcaag cgtagatctg ctttccagcc ttggacaatg
    43441 ccaatcactt cttcaactgt gtaggtttca accaattcca gaacggttcg tgacaatccc
    43501 acagccttag caccaaaaac caagcactta atcatatcca gcggattccg aacccctcca
    43561 ctaaccaaga gttcgacctt atctttccat tcttgggcat tgagaagggc ctgcatggta
    43621 gactgacccc attgattgag gtaatcacgc tggccactac gacggttttc gatataggca
    43681 aagctggtgc caccacgacc cgataggtcc actgtacgaa caccgaattc ataggctctt
    43741 tcgattgtct tggcatccat tccaaagccc acttccttga ggacaatagg aacgggaatt
    43801 tgcttgctat aatctgctag atgcgattgc cagcttctaa acttcctttc tccctcgggc
    43861 atgagtaatt cctgcatgac attgacatgc acttgcaata gaacaggatt catctcttct
    43921 acagtctgaa gtcctaactc gacaggcttg tccaatccaa tattggttcc aaggaggaga
    43981 ttgggatgac tagacttgac agaaaaagaa tcatccgttg gatttttgag ggctgcgcta
    44041 taagaacccg ttacaaataa aataccacag gtttccgcca cctgagccag cttttgattg
    44101 atttctcttc ccttattact tccaccagtc atggcattga tataaaaagg aaagtcccac
    44161 tttcgaccag caaactctgt cgaaagatcg atttcatcca gattgtaaag aggcaaggaa
    44221 gaatgaatca gctccacctc atcaaagcta ttataggaac ttttctgctc aagggcatag
    44281 aggatatgct cgtccttacg atttgtcgtc atgtcctatc ctttcttgat ataagagctc
    44341 aatccccaga tcggcccaac gattttttaa ggttttggtt gattgcgcat caaaactcag
    44401 ggcgatgcca cagtcaccac caccagcacc actactcttg gcaacggcct gcaaatcttg
    44461 actggcttct ttcaactgtc taagcaaagg cgtgtaaata tctgtactca agccttctaa
    44521 aagcttgctg gctacttcta cttgctcgat aatcttttct gatttcccct gttccaaggc
    44581 ttcgaccaaa gaaaccaccg tttcttttga ggaagttaaa aaattttgat tgatattttg
    44641 cttgatttgc tggaccatgt gactcgatac agccacttcc ttggtccatc ccactaagaa
    44701 atcacattct aaagttggtt tcacttgtga aattgaaaat ccccaatcac gctccagaac
    44761 tgtcgccaag ttttcttctt ctaaccaagc agccaccttc tggcgatcaa atgactggta
    44821 gagaaccaaa tcctctgccg caatacaggc aaggtcgccc atggaaccat tgtctcctcg
    44881 cttaagcaag acagcactag tcagcttgaa caagagattc tgatcaaccg aaagattata
    44941 gagagccagt aaagccttga caaccaagac aacgacgctg ccactagaac ctagaccaaa
    45001 ctttttccct tctcgttcca ttttgccata gattgctaga gaaaaaggtc ttaaattctg
    45061 accgcgaaca gcgaggaagt ctcccatcaa agcaatcgtt tcttgaatca agctgtagtc
    45121 aggattgggc cttaagtcca ctgcgaaatc aaacatatct gaatagatac ggtagctgtc
    45181 agaaaaagca atctcagccc tcatatagat gggaatatcc tttatcaaag ctaactgccc
    45241 tggctctaaa atagcatatt cacctgccca atagagtttt ccgcaagttt taacagcaat
    45301 catcttgact caaatccttt gtttttgaca caatcaagcg ataacgctga ccgaaaattt
    45361 ctgacaaatg ctccaagtct ttctcctgac agaagacctt aacattggga ccagcatcca
    45421 tggtaaagta gcaggcctct cctttctcac gaagctgacg aacaaagtcc atagcctcat
    45481 aagaggcatc cgtcagataa gaaaaggctg gactagcagt ctttgtcgta gcatgcatag
    45541 ccagggcatt tttctccgtt aattctccaa tcttggcaaa atcattttcc ttgagataaa
    45601 tcagcatatc ctgatagtcc ttctcagact gacgaaccca gtcgtcgaaa gtcgtcgagg
    45661 tttccacaca aagtttcatc ccgtcacggc tagagattgg ttttttcttg tcctctagca
    45721 ccaacataat catagctagt ttcaagtctg tctctacagg gtaaatttct ccactatcct
    45781 tatcccaggc tcctagtggt ccataaaaac tccgagaaga agagcctgag gcaaacttgg
    45841 cttcctgcgc taactgactt ctatccaatc caagcttgaa ataagcatta caagccttga
    45901 ccagggcgga caaaccacta gaacttgagg acaggcccgc tgccgtaggc atattgtttt
    45961 gagtatcgat acggacaaag ccctcaccag ctggacgata acggtcaata atcttactca
    46021 tcttggcatg ctcgacctca ttttgtagct gaccattgat gtaaaattcg tcagctgtta
    46081 cattggctgg taaaggcgac aaggtcgtct ctgtatacat attttccaaa gttagagaaa
    46141 tactgctagt agcaggcacc atctcttttt cttttttctt tccccaatat ttgataatag
    46201 caatatttgc gtaggaacgt actgtcacag gctctctatc catgtctgaa cagctccttt
    46261 ctcttctaat ctttctgcta gttcttgtgc gtgtgtcaaa ttggttacca aggctatgat
    46321 acaacctcct agcccaccac cgctcatctt ggcacccaga gcaccatgac taagagctgt
    46381 ttcaaccaaa gagtctgcct cagggctact gactccaatt tcttttaaat gtaaatgcgc
    46441 ttgactgagg atttgtccca gtccttcagc atctttttgt gaaatcgcaa cttctgcttg
    46501 ctgggttaat tctcccaagg catgcaaaaa cggtagggca tccttgccct tattttgaac
    46561 cacttggatg gcttcacgag tatgaccata aacacccgta tcggcaatca ccaaataggc
    46621 ggataaatcc atctcaagtt ctgtaaatcc tacgttcttg ataaagcgaa taggttggtc
    46681 actgagacag gtcttagcat ccaaaccact aggattcata tgggcaatca tttcagctcg
    46741 attgaccaag atttctagta catcatgagg cagatcagcc tgatagtagt caaataccgc
    46801 acgaatggcc gctatgctga tagccgctga cgaacccatc ccccgtttct cagggatagc
    46861 cgagtcaatc tcacaacgaa tgcaggcttc tgtgatattc aaatactcca gtgaggcata
    46921 aaccgccatg gacaaggtat cctcctcata aaggcgccaa ggactctctg caggaactac
    46981 cttacaggtc acctccacct ccaaaagagg cagggaaatg gcaggataac cgtaaacgac
    47041 cgcatgttcc cctattaaaa ttatcttact atgtgcctga ccgacaccaa ctttttttgt
    47101 cattttttcc ttttactaga cgaaaaaacg tcttattttt catacaagta ttaattcttt
    47161 cctatctatt ttattatatt ttcacaaaaa aagcgattgt ttccattcgc aatcgcttct
    47221 ttcattattg aacccattcg ccattatagt tgacagaata gccatctacg gtcgtattca
    47281 ctgccaaggc acctgagcta taagcatagt accatttgcc attgacctgg aaccaacctg
    47341 tcttcatgtc tccattacct gcatttaggt agtaccaagt taaaccatct tgataccagc
    47401 cagttaccat agctcctgat gaacggaggt agtaccactt gttaccaagg tattgccagc
    47461 ctgttttcat atcgccattt ggctggtcta aataatacca agtgatacct tcctgatacc
    47521 agccagtcgt catagctcct gatgaacgga gatagtacca tttattacct agatattgcc
    47581 aacctgtttg cataatacca gttgttggat ctaggtagta ccatggagca ggtttgcttc
    47641 tatcaatgtc aatagtaaca tgaaaatctt gagtccaacc cttagcaact tcaccaattg
    47701 gtagtggatt gtaagaatca tcaccaaaat ttcctagctt atttaaataa taccaattgc
    47761 cgtcttcata aatccagcct gtctttacag cataattatt atcaaaataa taagttctct
    47821 tttcagcaga tagaggatat tgttcaccgt atacttttcc tgtattttca gacgtttttg
    47881 cctctagtac ttgtttatct gtttgttcta gcaaagcacc atcttgtcca aaatagtacc
    47941 acttctcctg aaggccaatt tcgaagactg gacgattatc aaataaatca tcacgataac
    48001 ctgttccagg aatttctaag tattgccaac cgacaaccat ctctccaata tcaccaaaat
    48061 agtaagtttt accgtctatt ttatgccaat agattgcttt atgatcatct tttacataat
    48121 attttctatt atccttatca acaaatcggc cacctgtggt attcgcaaat accgtatttg
    48181 tagctagcaa accaaagaaa aagactgcta gtagaacttg catcattttt ttcaaaagtt
    48241 tcatttatat atcctcctaa aacgattgta gcaaagaccc gactgcatgt caatatataa
    48301 aaactcctca aaaaagcagt tacacaactg caactgcttt tctattcttg catggtgtaa
    48361 ccaacaccac gcacggtttt aatgtagctt ttttgtcctt taacatcaag cttgctccgt
    48421 agatagcgga tatagacatc tacgatattt gtctcggtcg cactttcata cttccagaca
    48481 ctttccaaca attgctcacg agtcaatact ttcttgcttc ccataagtgt cgccaaaagg
    48541 tcatactcac ggcgggtcag agcaatcatc tcttcaccac gataaaccgt gtgatgttca
    48601 acatctatcc taagattgcg gtaggtcctt ggaactttca tcagactaca gtgttgatca
    48661 atgaagtccc gacctcggaa gatcgccgaa atacgcgcta ccagattttc gataaggact
    48721 ggcttataga tgtatgaaac tgcaaaacgc tgaacaactt ccagctcttc ttgcaagtct
    48781 tcccaatgat ctaaaatcat gatgactgag gcaggtttag ttcgactcaa tttttctgca
    48841 aaatcctgag ccatcatatc tcccagatta acgttcaata aaatcaaatc atagtctgtc
    48901 tgaagagcca tggagagggc tttttgcccc tcctctacca gatcaacccg atactgctct
    48961 ttctggagtt ccaaacttaa aaaatgagct agatttcgtt ctttctcaag taataaaatc
    49021 cgtttcccca tggctgacct acttattttt cgtcatacca agagtagtgg aaggttcctt
    49081 ctttgtcttt acgttggtaa gtgtgagcac caaagtagtc acgttgtgct tggatcaagt
    49141 tagccggaag gtcagctgaa cggtagctat caaagtaagt aatagctgct gagaaagttg
    49201 gcactggcac accagcttga accgcaagag ctacgatatc acgcactgct tgttgatact
    49261 tagcagtaac atccaagaag tattcatcca aaagaaggtt ggcaaggtct gcatcacggt
    49321 tgtaagcatc tgtaatcttt tgcaagaaac gagaacggat gatacagcca tcacgccaga
    49381 tagatgcgat atctgcaaat ggcaagttcc agttgttttc tttagaggct acacgtaatt
    49441 gagcaaatcc ttgtgcgtat gaaatgattt ttgagaagta aagggcttga cggatttttt
    49501 caatcaattc agccttgtct ccttcaaagt tgaaggcagc tggttttgga agcaccttgc
    49561 tagcatgtac acgttcttct ttgtaagttg aaatgtagcg tgcaaacact gactcagtaa
    49621 tcagtgacaa tggtacacca aggtcaagag atgattggct cgtccattta ccagttccct
    49681 tgttacctgc agcatcaagg atatagtcta cgattggtcc atcttggcct tcatcgtctt
    49741 tacggctcaa gatatcagct gtgatttcga tcaagtagct gtctaattca cccttgttcc
    49801 actcagtaaa gatttcagcc atatcctctg cagaaaggcc tagcaagtgt tgcatcaagt
    49861 catagctttc tgcgatcaat tgcatatcac cgtactcaat accattgtga accattttca
    49921 catagtgacc agctccatca ggaccgatgt aagtcacaca tggcttgcca tcttctggtg
    49981 ctttagctga gatttcttca agaacatccg caaccaattc gtaggcctct ttttgtccac
    50041 caggcatgat agaaggacct tcaagggcac ctttttcacc accagaaacc ccagtaccga
    50101 taaagttgat accagagttt gccaattctt cattacgacg gatggtatct ttgtagaaag
    50161 tatttcctcc gtcaatcaag atatcaccct tgtcaaggtg tggaagaagg gcttggatag
    50221 tagcatctgt accaggtcca gcttgaacca tcagcatgat acgacgaggt ttttcgattg
    50281 agtttacaaa actttcaacg tcatagcttg gtacaaagtt cttttcagga tggcaagcaa
    50341 tcacatcttc cgttttttct ttactacggt tgtagatagc aactgtgtaa ccacgtgatt
    50401 caatattaag ggcaaggtta cgacccatta cggccatacc tacgacacca aagttagctt
    50461 ttgtcatttg acactcctct tgtttcattt gttttatttt atcattttta cttttgaaaa
    50521 gaaagaattt tgtaacgact gcttagtagt ccaagtcatc cgcatgacca gcgccatttc
    50581 cgacaaagta gcctgtctta cagttaaggg taaagagata ggttccatct ggcttataga
    50641 ggttgtaata accattgccg ttaacgatat tgacacgttc aaggatatat tggtctccag
    50701 tgatatagcc acgtgaacgt gaagtcgcta gaatttgttc caagacacca tccgcaaaat
    50761 cccaggcaga gttattacta tcatcaatag cagactgatt ataggcaaca cgactggcac
    50821 ttctttgaac agcaacccct gcactcgaga gacccatatt gacttcactg cgactacttc
    50881 tagtctcatt tgaactactt ggttttggct cactagtcgt atttgaactt gcttgactag
    50941 agcttgagct gctagtttga cttgaacttg agctagaagt acttgtttgc tggctcttac
    51001 caagactgat agccttatct agcactttat caagctccgt atttccagtt ttaatatccg
    51061 taaatttagc atccgatttg gctttggcat tggtatccaa cacaccatcc acaatagctg
    51121 gtttttcaaa ttgtgcattg acatcttgaa tagccttgat ttgcgttgct agactatcat
    51181 atttagattt ggcaagcgta tgttcacgac taccttccag tttatcaagc aaggttttga
    51241 gttgactcag tttatcaaac tggctatttt tcaaagccgt tttattgcta tctgtgtaaa
    51301 aggcgtcata aagtgtatta aaatcatcca catctgattg attggctgta gttgattgag
    51361 aagtttcaat ttccttggtc gaacgagcca cttgacggta gacataataa gcactgacac
    51421 aaataattac tgatacaagc gccaaaacgg tcaaaataaa gcctttttta cttttctttt
    51481 ctgagtcctc ttgatccaga cgagaaaggt tttgctcctc ttccacttct tcagtcattt
    51541 ctgttggatt ttcatcatct agcaatagag gatccaagcc ttgctcctca tcgtccagag
    51601 gcaagggtag taagatgtct tcagaagatg gaacttcctc cgaagaagct tctgacttct
    51661 ctacagcctc acgcatctct tgaattaaat catccagact ctgagtttca acgaactcct
    51721 cttttttgta ttgacgagtc gcaaacttat ccgcctcaat ttcatctctg tgttgcttaa
    51781 catacttgtc caaaatggaa tcctcaggca agactcctgc ttccacttct tcatttttac
    51841 gaatagcttg accaactgtt agctcttttg cttcatcaaa atcaaattgc ggttcttgac
    51901 cttctttttt atgacgattt cgtctttttt tactcatgag tatccctttc tattttacct
    51961 cttgccgttt gacacgctga ccaaaatatt gatatagatc cactttcaag gttccgttgt
    52021 ataacttacg cttcttatct gcttggctac catacttgct ttcaaaagct tcatcactag
    52081 tcaggataaa tttgctccaa gttttcagcg gtgcaaatac ttgccccatc tcagcataga
    52141 gcttggtcac ccctgcatca tctgacaaac gttcaccata aggcggattg gaaatgatta
    52201 ctccattgat tttatcggaa cgtaaatcct gcacgcgcat ctgcttaaaa gtaatgtctc
    52261 ctgcaacacc agctgcctga gcattggcct tagcaatttc caccatgcga gcatcaatat
    52321 cacagcccat gatatccagc tcaagctcac ggtctacttt tttagccgct tctgtgcgca
    52381 cttcttgaat caggcgatcg ctgatccagt tccattcctc aaatgcaaaa gagcgacgaa
    52441 gacctggcgc catctttcta gcaatcataa ctgcctcaat acagaaagtc cccgaaccac
    52501 aggtcggatc aatcaaaggc ttgtctggat accagttaga aagttgtaaa atggctgctg
    52561 ccatattttc cttgatagga gcgccacctt tttcggtacg ataaccacgt ttaaagaggc
    52621 tagacccggt cgtatcaatc atgacagttg ccacatcttt gagaatagag acctcaatct
    52681 taaactctgg gccattctcc atcagaggaa ccccttctgg gcgagcatag tgtttctgca
    52741 atttcttgac aacagctttc ttagaaatag cctgaacact gggctcattg tgaagtttgg
    52801 acttaacaca tttagctttt gaaatcggga accgagctcc aagtggtaaa taattttccc
    52861 aatctaaagc gaaaactccc tgaaatagct cttcaaaagt cttagctggg aacgttccta
    52921 cgataatttt gatacgatct gctgcccgaa gccaaaggtt ggtttcgata atagctctca
    52981 cgtctccttg aaaacgaaca cgtccatttt caacctgaca atcgtagccc aactctcgca
    53041 cttcacgacc aacgacagcc tcaagccctg ctgccacagt tgcaattaaa ttaaattctt
    53101 ttttcatgtt acagtcttgc aagacctttc tatatgtcca ctttaaaaaa tgaggttgag
    53161 aaaatttctc agccccaacc tatatgcaat tttctataag ccatgttttg ttccagaagt
    53221 gactaggacc acttccttcg ataatcatct gtctaccact aacagctcta gctgatagca
    53281 gtcagaatac tacgttcgtt tccgcatact ccatgccccg accaaaattt gggttgctag
    53341 cttgaggggt ttaccgcgtt ccactctctc tgtttccaga aagactccgt cactgtggca
    53401 ctttcaagcc tactctggcc tatccaagga cttagccatt tcaactgccg taacgatttc
    53461 tcgtccctag gcttatggtt tcgcctagca caaacactac aggcatcaca gcctgtgcta
    53521 gcatggactt tcctcatgag aagcaattct cctcacgcga ttatccaaaa attgcacatc
    53581 tcaaataact acttaaaaat ctgagttatc taaaatttgt ttaccaaaaa cttctttttc
    53641 caatctattc aggcgtttca aaatatcaaa attcgtcata gaacttgtaa ttgccgcttc
    53701 aaggggttct gcttgaactg gtgaaggttt cggtttacga gttaattctt ccttcaaatc
    53761 cgcaatttcc tgacgaagtg acttgaccaa ggcagcatag gtttcatagt ccttgatgac
    53821 atcgtctaaa aactcgtcaa cttctacttt attatagcca cggacttcac gtccaaactc
    53881 ttgttcaaaa atatctttcg ctgaaaaaat aatacttgcc atgtctctct ccattctcgc
    53941 ttgctagtat tattatataa aaaaaggcaa acaaaaatca aggtcaaagc ttcaattttc
    54001 ggaaaaattt tcagcaagtt catttaattc atcaaatgtt aatctcttta taaaatagtc
    54061 ctcttgattt ttcatctttt ggtaaaaata agctagtttt gtttcatttt cttcatcata
    54121 aaaaagatag gaactagtcg tgttttccag caaaaactgc tggtaatctc ttaactgccc
    54181 cttgtgttca taacgaggat aagcatattt gacaaagtct acctgcttaa agcgactcag
    54241 tttcatctga ttgccttcat tcaaattttc cccatggttt tcaaaagcaa aaatggtggc
    54301 caactggaaa ccgtattcgg ttttcatctc ctgagcaacc tctaaaaccc aatattcaaa
    54361 acccaaactt cctgtaaaca caagccaaga caccccatct gctgccatag cctctaaatc
    54421 ttttcgtatc gcttttttaa tcaatttaag acgaggatcc ttatcagaaa ataaacccaa
    54481 atcaaaagca gaatagccta aaaccaaagc tgtagccatt tttaaccctt tctgtgcaaa
    54541 ttatggtata ataaagtgat gttattgtac caataaggag aattatggtc aactatccac
    54601 ataaagtttc atcacaaaaa agacaaacat ctctttctca acccaaaaat ttcgcaaatc
    54661 gaggaatgtc ttttgaaaag atgatcaatg ctaccaacga ctactatttg tctcagggct
    54721 tggctgttat acataagaaa ccaactccta ttcaaatcgt acaagtggac tatccacaac
    54781 gaagtcgtgc caagattgtt gaagcctatt ttcgacaagc ttcaacgacg gactattctg
    54841 gcgtttataa tggatattac atcgactttg aagtcaagga aacaaaacaa aaacgtgcga
    54901 ttccgatgaa aaattttcat ccacatcaga ttcagcatat ggaacaagtc cttgcccaac
    54961 aaggaatctg ctttgtcctt cttcactttt cttctcagca agaaacctac ttattgccgg
    55021 cattcgattt gattcgcttc tatcatcaag ataagggaca aaaatcaatg ccacttgaat
    55081 atattcgaga atatggatat gaaatcaagg ctggtgcctt ccctcaaatt ccttatctca
    55141 atgttatcaa agaacattta ttaggtggta aaacaagatg aacaaaccaa cgattctgcg
    55201 cctaatcaag tatctgagca ttagcttctt aagcttggtt atcgcagcca ttgtcttagg
    55261 cggaggagtt tttttctact acgttagcaa ggctcctagc ctatccgaga gtaaactagt
    55321 tgcaacaact tctagtaaaa tctacgacaa taaaaatcaa ctcattgctg acttgggttc
    55381 tgaacgccgc gtcaatgccc aagctaatga tattcccaca gatttggtta aggcaatcgt
    55441 ttctatcgaa gaccatcgct tcttcgacca cagggggatt gataccatcc gtatcctggg
    55501 agctttcttg cgcaatctgc aaagcaattc cctccaaggt ggatcaactc tcactcaaca
    55561 gttgattaag ttgacttact tttcaacttc gacttccgac cagactattt ctcgtaaggc
    55621 tcaggaagct tggttagcga ttcagttaga acaaaaagca accaagcaag aaatcttgac
    55681 ctactatata aataaggtct acatgtctaa tgggaactat ggaatgcaga cagcagctca
    55741 aaactactat ggtaaagacc tcaataattt aagtttacct cagttagcct tgctggctgg
    55801 aatgcctcag gcaccaaacc aatatgaccc ctattcacat ccagaagcag cccaagaccg
    55861 ccgaaacttg gtcttatctg aaatgaaaaa tcaaggctac atctctgctg aacagtatga
    55921 gaaagcagtc aatacaccaa ttactgatgg gctacaaagt ctcaaatcag caagtaatta
    55981 ccctgcttac atggataatt acctcaagga agtcatcaat caagttgaag aagaaacagg
    56041 ctataaccta ctcacaactg ggatggatgt ctacacaaat gtagaccaag aagctcaaaa
    56101 acatctgtgg gatatttaca atacagacga atacgttgcc tatccagacg atgaattgca
    56161 agtcgcttct accattgttg atgtttctaa cggtaaagtc attgcccagc taggagcacg
    56221 ccatcagtca agtaatgttt ccttcggaat taaccaagca gtagaaacaa accgcgactg
    56281 gggatcaact atgaaaccga tcacagacta tgctcctgcc ttggagtacg gtgtctacga
    56341 ttcaactgct actatcgttc acgatgagcc ctataactac cctgggacaa atactcctgt
    56401 ttataactgg gataggggct actttggcaa catcaccttg caatacgccc tgcaacaatc
    56461 gcgaaacgtc ccagccgtgg aaactctaaa caaggtcgga ctcaaccgcg ccaagacttt
    56521 cctaaatggt ctaggaatcg actacccaag tattcactac tcaaatgcca tttcaagtaa
    56581 cacaaccgaa tcagacaaaa aatatggagc aagtagtgaa aagatggctg ctgcttacgc
    56641 tgcctttgca aatggtggaa cttactataa accaatgtat atccataaag tcgtctttag
    56701 tgatgggagt gaaaaagagt tctctaatgt cggaactcgt gccatgaagg aaacgacagc
    56761 ctatatgatg accgacatga tgaaaacagt cttgacttat ggaactggac gaaatgccta
    56821 tcttgcttgg ctccctcagg ctggtaaaac aggaacctct aactatacag acgaggaaat
    56881 tgaaaaccac atcaagacct ctcaatttgt agcacctgat gaactatttg ctggctatac
    56941 gcgtaaatat tcaatggctg tatggacagg ctattctaac cgtctgacac cacttgtagg
    57001 caatggcctt acggtcgctg ccaaagttta ccgctctatg atgacctacc tgtctgaagg
    57061 aagcaatcca gaagattgga atataccaga ggggctctac agaaatggag aattcgtatt
    57121 taaaaatggt gctcgttcta cgtggaactc acctgctcca caacaacccc catcaactga
    57181 aagttcaagc tcatcatcag atagttcaac ttcacagtct agctcaacca ctccaagcat
    57241 aaataatagt acgactacca atcctaacaa taatacgcaa caatcaaata caacccctga
    57301 tcaacaaaat cagaatcctc aaccagcaca accataacat ttatcaccca gatttttctg
    57361 ggtgattttg tcatagcact attgtattta tgtgcttaac aaaagcctga gaagacatct
    57421 tctcaggctt tttctgtact ataaacctca ttggaaaaga tagagactgc ttccgtaatc
    57481 ttgttaagag gttttactaa atactagtct ttcttcgttt ttactacaaa gagagcagat
    57541 agggctagac taacacttgc taggatgagg gctgtgtcag attgactctc acctgttgct
    57601 ggcaagattt gttcaggtgt ttctggtcta gctatttctt gcttataatc tggcgtctta
    57661 ccttgctcgg aagctaaaga tctaagttta aactcaggtt tctctacagt tggagcatct
    57721 ggtttcgtag cagaatcttt taattggttg agataatctg caaagtattc caccattctt
    57781 tccgtcaaga gatggttatc cgtcgcatat ttcatgcttg cctgaacgct agctacttcc
    57841 tcttgattgt ctttgtctgt taatttctga gccttaacca aagctgcttc atagcctgac
    57901 aagtcaagag gtgtttctgc tacctgtgga cgagtaaaga taagttccgc tgcagattgg
    57961 tatttatctc caccatctcc gtatgtcttg gtaccagtaa ggacaatttt cttagcctta
    58021 attgtcttac caaaatcaat gtcttttggc ttattgttat ctggccaatc agttgcagta
    58081 aaggtatgct ccttgccaga ctcatctgtc acaacaagtt tcacatctcg caagttacca
    58141 tttgaacctg atccacgcgg aacatagcga agtcctgtga tttcagttgg ttctttcaag
    58201 accatagttg caggcttgcc tacatctcca ccattccaag atgtatgcca tagactagac
    58261 acattgccat caaaggcatt tgcaagacct tcttgagcct gagcaggagc tgtaagactt
    58321 gcaaagtcat ctgctaccaa agccgttttc ttctgaacca aagcattctt caaagcttca
    58381 atcttggcaa tctctgcacg cgcttcttcc acactgatat catcatcggc ctgactgagg
    58441 ttaaagaccg cctctttcaa agcatccata gactctttgg tgtagttagt catggcaacc
    58501 gttggcaagt agttcttcag agcattttct gtcaacatct tacctgttag ggtaatttct
    58561 tcgatttgaa gattatccat catgaagtcg ttataaccac ggaagttggc atttccacca
    58621 gaatcaccac gagtattact tgcatttcca gttgagtaga tacctaccca agtatcgcct
    58681 gtttctgcac ctgtcacaag gaaggttgcc ttcttggctt tcttagaatc tgtccaagta
    58741 tttggcaatt catgcatttc caagttgctt gcttgagtac cacgacgacc tgactggaat
    58801 tctcccttac cgactacaaa agcataggta ttgtctgatc ctgcttcgta ttcaaaggtt
    58861 acacggtagg tcttacctgc ttcaaaacgg aagttttgtg ggatggtttg gtaaaccaag
    58921 ttacgacggc tcactagtcc atttgtcttg agtgaccaat ttccttcgat aacatcatcg
    58981 actttcttac cattccaacc acgttgtgta tatggattgt gtttttcaga caagtgagtg
    59041 cggttatctt caacaccttc gacaccaccc actacaaatg ggaagatacc ctgagcaaca
    59101 ttttcaaagt cttgcttgaa ggtgccttta cctgtatcat gcttgtctcc gtacatgctt
    59161 gaattgtttt caaaggtacg aatttcatca aagtaagttg cttgatcacc agcttcacga
    59221 ctcaatgtca gagtaacatt tgagacgtcc gctccagttg taaagaaggc gtacatgttt
    59281 tggaagtaac ttgtatcgtc aactgtagca ttgtcacgac gtgtattgtg ggcgtaggcc
    59341 ttaacatagt tgagcgcgag agacttattg gtataagtag tcacttcttt ttcaccagta
    59401 ttcacagtga tacttgcctt ggcattacta cggttatcta caccaacata aacggcatac
    59461 ttggtatttg gtttcaagcc agttaatttc tgagtgagac taactttttc tttgtttcct
    59521 tgaatacgaa gcatatcgtt tgccccttga gacttgacaa tttctgcctt agaagcatcg
    59581 cctgaaatgg tccaatgttt caaggtaccg ctattaaatc cttggtcata gatgtgcatg
    59641 ccttcactcc atgacatttc aggattggtt tgtttcgaac gatagagaac gtatggttga
    59701 tttgctagaa gatctagggt aattttacca tcttttacag ttagttcttg ctcttctgtc
    59761 ttaccttggt cagttagctt gtaaaggtaa accttgctct ttgcccaatc gcttggaagg
    59821 gtccaagttg ttgcaccggc ctgcgtattg aagtagtaca tcttttcctt atcagtagaa
    59881 agtttcttac catttgcatc ccagttccaa ggagtcaagt aagctgaacc atcttggatg
    59941 acacgtccgt tgagcgttac tgtacgttcg cgatattgtg ggctattgac atcatttgac
    60001 ttacgagtta caactacttt attattgtca gcatctacca attccactcg catttctgga
    60061 gtccatttat aggtgctacc gttatcggtc atagtcaccg gtgtaccatt ttcccattta
    60121 cttacagtga agtgttggaa gtacttggtc atgacatcat gggcaaataa gttggttaca
    60181 tagccattgt agtcacttct tccttgccag ccttcaaagt ctttcatgct gtagccacct
    60241 agcagtggat agttggctgc accaccataa cttctgtagt ccccaaccca agcatctttt
    60301 tggtggttac ggataaagcg ggtgatggca ctgttgatac ctttattggt gtagccaccg
    60361 taagtcaagt cagctgccca gtgatggaag gtagagtcgt actcaccacc atggccccac
    60421 tcgatcgcaa agcgccagcc ttgtttgtta atttctttag caagaacgtg ggtagcccag
    60481 gcaccgttat cacctgattg accattaccc caaacgtcca catagataaa gtcgagaccg
    60541 tcaccaagtt ttttcttcaa atcttcccaa cgtgccaaac gaccatgagc taggtcatag
    60601 gcagcatcaa tgttgatacc ttgatctagc cagttccaac catagctata gcttccatct
    60661 ggattcttac ggagaatttt ttcattgaag tatttagact caggataagt ttctgaagcg
    60721 ttaacgtgga tacctagatg agctccatat ttcttagcct tctcaattag ggtcttgaag
    60781 tcttcgacac caccgatacg cttaccaata tcagcatagt tcaagtgacc agagtcatga
    60841 ccttcactac catatccttt aaggagaaca ccttgcccaa gaccatctgt gtggagattg
    60901 attttcttga taccatccaa ggtcataagg aatgggtttt gtgcttgaga accaaagttc
    60961 atcgcgatac ggtaagctgt gatatcctta actttttccc aaccttgagg gttgttcata
    61021 atgctacgat aagcaatggc accatcttgc caatcaactt tcttgtctgc attggcatct
    61081 tcagtgataa caaccttagc acttggaagt tccttcgtgt attctgggaa aacaatgccc
    61141 ttataagctt tttcccattg ccattcagag ctgtggattc ctacatagtt ggcatttccg
    61201 actgtttctt tataagctgt caaacgagtc cagtcattcg aaccaccacc atagctgttt
    61261 tgagagttac tccaaacacc agcagcaagc ttatctgtag aaacaaatcc atacatgtaa
    61321 cccttagcca aatccttcat tggattggtt acatcgatat gatcatctcc gctgacatgc
    61381 gtattgtttg acatggttgc cccatcaaac ttagcaccag tttgatcact agaaacagag
    61441 actaaagcat tgccgaggaa actaatagaa gaaagtagtt ttctttcgtc atcgatcttt
    61501 tgacctggag tgacttgatt gtggttgaca atcttggtca catcaaagtg caattgattg
    61561 tccacaactt gcaagcgtac tgtcatttcc gcattgatta agtgagcatc atcgcgaagc
    61621 ttcatcaagt actctgctgt tgtctcattg attttcttat aagtgacttc aggggtgatt
    61681 cggtggttat tgataaagac ttggttgaac tgttgcacct gtcctggcaa agtatgtcca
    61741 ttcaagctgt attccttgac acgagggaag gcttggtcaa tcactgcttt gaggacctta
    61801 gactgaatcg tgtcataagt caccttgcta tcgtcaacaa ccggacctgt ttctttttca
    61861 gcaggggtat cctctgtttt taccccctct tggttatccg ttttaacgct aacaactgtt
    61921 cgctcatcgt cataagagcc cgccttgaga agaatcttct tctcattttt aagatggtca
    61981 ttgaccgcag ctggtagagt cactgtgtca aagagattga catcgttatt gctggcattt
    62041 agctgaccgt ctgacttgag agtgatagag agacggtttg ttgatcctgt ttcaggagca
    62101 gcaacacgac tacctctata ccaagtgcta gttgttggag atttatactc ccagaaccag
    62161 ccatccttgt cataaccgac aaaaacatta ttattggtat ctttaaattt caagaagaca
    62221 ccaaagcgtg atttaccctt ttcagaatca tctttgaagg ttaaatcaac agttgcattt
    62281 ccattggcat caacggtcaa gcccttcttt tcaaacaggg ctggtttgcc tgcgttatca
    62341 ttttgagcag ttgaggatag ttggttgtag cggacacctt tttcttctcg gatagtgact
    62401 gttccctgtt gttctttttt ctctaccgtt tgccattcag gagttaccgt cttaggtgtt
    62461 tcaggtttag cagctgcagg tttatcctct tttggttttt cttcagccgg tttttctttt
    62521 tcaagtgcta atagttcttc ttctgtctta ggtccatctg taacttctgg agaaccttgg
    62581 tcttctccca ccttaggcgc ttcaaaatca cgcccatcat tctctttcgc tgttgcaaga
    62641 gcagtagcta aatcagctgg taagttcgcc gtggaaccag actgcacgct atctgcaaga
    62701 accggacttg tcccaaagaa tgcagctcca atcataacag aagcaacacc taatgaaaat
    62761 ttccgaatac tatatttaca acgtttttca aataatcctt tattcataaa cttctaaatc
    62821 ctttcatttt ttggcaagcg tttacatttt ctttttaaaa aatactcctt cctctgaaag
    62881 tgcaatgctt aaccctgata aataaaaaat aattatactt ttaatataac aaataatagc
    62941 tgataaagca ataggaaaca agtaaaatta acaaaaattt tctctattct gacaaaaaga
    63001 ggctccaact tttgggggtc agtacattta gaatttttct ttacaaatgt aaaaaaggat
    63061 tcagcattca agagaaatac taaatccttt cttatatttt gcaacagtta tttcacatgt
    63121 tttgcgagat cttcttgagc ctttttatta gactcttctt tttctttcat ccatttttcc
    63181 tgagcttttt ggtattcatc tacagtgact gccttgtctt gaagttccaa gtatttatat
    63241 aagattggtt cacttgtacc tttatttcct gacaatgcaa atggtattgt aaatggtacc
    63301 atcttagaca agattgggcg ccctgtacga gatgtagttg gaataatcaa agcactatct
    63361 gtcaaccaag cttgggctgc agcgtattta tcatagcgtt tagcaacatc tgtagcctca
    63421 tcaccagcct cagtaaccaa tttttcgtag tcatatagac ctactttttt agcagctaca
    63481 ttatcttccc ctgagtcaaa ccctaaatat gttttagtac tttctcctac agatggtttg
    63541 atgatatcaa ggtaagttga tggatcggca aagtctggac cccaaccgac attatctgat
    63601 aaatcccagt cttcgccagc agcattttca gcaaaatatg taatattgtt tacttcgtct
    63661 ttttgtagtt gttggatatc aataatgaca ttatcagctc ctaaagttgc ttccaaggat
    63721 tgtttcatag attggacgcg ctgaactttt gtagttgctg tctggtcaac tggcatatcc
    63781 aaatgaattg ggaatgtcac accttctgct tgtaaggctg atttagcttt agcaaattca
    63841 gccttggctt tttctggatt gtaaagacca tcctgagaat ctgcaagatt aacatccttc
    63901 cattcatccc cataagtgac caatttctct ttgaccatat cgccaaagtt tttaccatct
    63961 gcttgaacaa atgttggtgg cacaaagaga ttacgcaaga ttttacttgc tccagtttgt
    64021 ccattcaact gagaggcata ggctgtacga tcaaaaccaa aggcaatagc ctgacggaaa
    64081 tccttgttta agagagcctt tttagtcgat gccttttgtt cgtcgctggt cttagatgtg
    64141 tatttatagg actgacggtc aatatttgta ccaactagat acgtaataga gtcttgttga
    64201 gtatagacaa tattgtcctt catactcttc tcaagctctg cgaaacttgc acttgttgga
    64261 tagagacgag ctgctgtaag gctaccatct ttaaagtttt ctgcaggttt gctggtatct
    64321 tgaccatccc agaatgacaa tttaactttg tcaatatgca cattgtcctt atcccaatag
    64381 ttcggatttt tcgcaaattc aacagaagat ttggtcacaa tggatttcaa caaataagga
    64441 ccgttataca agagactact tggatccgta gctttggcaa aatcatcccc ttttgaattc
    64501 aaaaactctt cattaactgg cgcaagcaca cccatggttg ttttagaatt ccagaagctt
    64561 tctggtttgt tcaaagtgta ctgaactgtc tgatcatcca aagccttaat tcctacttgt
    64621 gagaaatctt tgatttcccc ttttacatag gcatccaacc ctttgattga ttcttgaaca
    64681 aggtaaagag catctgattt tttatcagca gcatatttta gtcctgttac aaagtcttga
    64741 gctttgactg ccgcgtattc ttcaccttca gaagtatacc attttgcatc cttacggata
    64801 gtataagtgt aagtcaatcc atccttggat acagaccaat cctcagccat agacggcaca
    64861 aagttcccgt agcgatcatt ttctagcaaa ccatcaacca cgttactggt aatatttgct
    64921 gtcgcagcct tagcagttgt caaatagttg aggttatcag ggtctgtctc ataaatgtat
    64981 gagaatgtct tctcaccttt agcgcttgaa cctgatccag agcatgcagc taaagtagtc
    65041 gccgccaata atgtcacgcc cgcaagggca agtagttttg aacttttcat cattttctcc
    65101 tttaaaactt tctctccatt atagactctt ttcagaaagt tgtcaacaga attttcagaa
    65161 tttttgaaaa ttatttttca aacaacatct ttgcaaaaaa tatgaatatt atcaaaaatc
    65221 cctcaactac atcacatagt caaggaatta acctatatat ttaagcgaag ttaaacaatg
    65281 agagagtact ataccacttc ctggatattt tcttttatat tacaattaaa ctagataagg
    65341 tgcaaaatac tataagttat tttatttgtc tcctcagtat ataggataaa atatttaact
    65401 gtaagaatta caggatagct tatagtgcat aatcactgat attgtatttt ctagttaact
    65461 aaccaagaat attttggaaa tactttttta aatagcaatg taaagactaa tcccaaaaat
    65521 aaagtgaaaa caaatctaat taaaaatata ataattatac caaatgaagt aaacataaat
    65581 ctatcactta caaaataaga aatacttaat ataaaatagt ttaaagtatc agaaaaaata
    65641 tatatcccta aaccattaat caaaatgaga ttaagtagtt tactatctaa aattttagtt
    65701 ttattactta aaaagtacga aatattgtaa caaataagtg atcctaaaat agctaataag
    65761 tcaacaaaaa atcgactcaa tactttaaaa tcgcttttaa atagaaaatt taaaaccacc
    65821 aaaaatataa ataacacaaa gaataaaagg ctaatccatt tgtgattttc caaaaaaata
    65881 ttatacttcc ttcttttaga ttcgaacaaa aatcccatgg aaaaccaaaa aagaaactgc
    65941 aatggtgcac ttactaacgt tatatgaatc aagaaactca gtacatgtat aatatataag
    66001 gacaagtata caaatataga agtatctctt cttaaacaat aaaaactaat tataaagata
    66061 ataaataatg catacaaata ccataagtga gaatttccta ataacaagaa ttgaccagtt
    66121 atagctctcc aaaacgaaac accattgtag tagtttgata tatattttaa tggcaaacta
    66181 tataataaag taaaaacaaa aaatggcaat attaatcttt taaacttact agttaataat
    66241 ttctcaatct tattccatcg atcttttttt atttgaatag agaaaaatac acccgatata
    66301 gccataaata atggcatatg aaaataatag ataatttcca taaatttacc aagtatctta
    66361 tatagagtaa atgctgaatg actatttaaa tattgttgat aatccattcc accataattg
    66421 ctcgatattt tataatacgc actatgactt aacacaacta aaataatagc cataattttt
    66481 aaaatatcat attcttttat ctttttcaca ttaaatctcg ctcctctaat tgtagttttt
    66541 ctttatagaa aagatataag gtcattaaac ttgaccttaa tgtaattgac tactttccta
    66601 actcacttaa tacgacttct aaggcacgtt caatgaccac atgcatgtcg tagtatttat
    66661 aatcggccaa acgtccgcag aaaatcacct tatcattctg tgctgcttct tcttgatatt
    66721 tagcaaacat agcattgttt ctctcatcat tgattggata ataaggttca tctccgcgtt
    66781 tccaatcagc tgggtattca cgagtaatga ccgttttagc ttgcgtacca tactcaaagt
    66841 gtttatgctc aataatacga gtataaggaa tctcacgctc cgtatagttc actacagcat
    66901 ttccttgata attttcctcg tccaaaattt catgatcaaa gcgaaggcta cggtattcta
    66961 actctccatg cttgtagtca aaatactggt cgatcatccc tgtgaagaca actttttcag
    67021 ctgatgcttc taactcttca cgatgagtaa agaaatcaac accaagctca acttcaacgt
    67081 ctttaagcat attttcgatg atgacattgt aaccaccaat aggaattcct tggtaacggt
    67141 cgttaaaata gttattatca aatgttaaac gaactggaag acgtttaatg ataaatggag
    67201 gaagttccgt tgctgagcgt ccccactgct tttcagtata acccttgatt aatttttcat
    67261 agacatctgg accgatcaac ttgatagcct gttcttccaa gtttttaggt tcaatgtcct
    67321 tcatgtgagc cgtttgctca gcaatcttat ctttgacctc ttgaggagtt tttgtccccc
    67381 acatagcata gaaagtattc atattgaaag gcagattata aaggctaccc ttgtaatttg
    67441 ctacaggcga gttgatgtag ttgttaaatt cagcaaattg attaacataa tcccagactt
    67501 ttttattaga agtatggaag atatgtgcac catatttatg aacattaaca ccttctacat
    67561 tctcacaata gatattccca ccaatgtggt cacgtttatc aataactttt acttttttac
    67621 cgcgttttgt agcttcgtgt gcgaagattg ctccagacaa accagcaccg acgataagat
    67681 aatcatacat agttaactcc attatttttt aataatatgt tttaattctt tgatatctac
    67741 cacttttaga gatagaattg caaaaagata aatgattcca ccaagcactg caaatactat
    67801 aacatttata gttggcgaaa attgtataag tgtttttgaa cctagcagaa tgccatacat
    67861 gatagctgat gctaggacta tttttgtcaa agatccgata attggaactt cttttaggta
    67921 tctacgggta aagtataatt gtatcgccca tactaacgcc tctgtcgaaa cagaaacaat
    67981 ggctgctcct atatatccaa gtttaggaag gaatagtaag ttcaaaccta cactgacaat
    68041 tgcgggagct gttgttgaaa tcatgaactc tttattttga ttgtgaggta tcagtatctg
    68101 agttcccatg atattggtcc aaccgataaa gaacatacgg aagctcataa tggcaattgc
    68161 ataacgtgca tcctgaaaat cctgcccaag gaaaaactga acaaaatcat cattgacgat
    68221 taaaattcct gccatcattg ggaaaatcac taaattataa atgaggaagg atatttcatg
    68281 catcttattg actgctctat gatttcctgt tgctaataag ttagctactc gaggcaacat
    68341 aacacttccc aaggaagtta ccaaggtcaa aagtatattt accaacttta gagcctgatc
    68401 ataaatccct acatcttttg tagaagccaa tgctccaagc atggtacgat ctaaggtaac
    68461 atacaaagag attgctactt gaggaagaaa taataatatg acgggcttca aatgaggctt
    68521 agcatattct aaatcaaaat gaggtctatc aataaactca cgagcaggca accacatact
    68581 tagttgcccc aagagttcaa atatggttag caaaaaaaca tagagatata ggtcatttgc
    68641 agatttgaca aagaggaaga ttgaaatgac tccaacaagc ttgaccgtga tatttcgaac
    68701 agtaatcttt cgaaaatctt ccaacccttg aaagagccag gaaatgtcta aaccttttga
    68761 aactaaactc aagcctagaa tgtaggctac cggattttgc ataaagggaa ggatcagaca
    68821 aagaagaaca tataaggcca gagaaagaac tgttgcccct aattgtagag agtagattcc
    68881 ccaaaagttt ttttgaattt cctcgcgatg ccctgaaatg accttagtcc catagttagc
    68941 aactcccagc gtcgctaaga ggataaagta ggtgacaatg gaattaaagt atccatacgt
    69001 ccctaaatca tccgaagaaa agacccgtgt tacataggga gtcgtaatga ttgggagtat
    69061 aatcactaat aactgataag aaagattata ggcgtagttt tttagtactt tcatacctgc
    69121 actctcctat tgaacatcat cttaagcaga atacttaatc gattcataaa taccctcaga
    69181 agaaattgat gctttatttt gctctctggc atatttcatc aaaatccctt ctcttgaaat
    69241 tctttttcta gactgtttgc ttttctttta actagatttt taataacaag gttaaaaaga
    69301 tacttcgttt tataattgac ataaagtaaa tttgaagtct ttgtttttgt ttcaaattta
    69361 aatttgaatc cacttttttc agaatatgaa aacagttcat ataccttgtc aagttcctca
    69421 ttcataacat acaaaatatt ttgcttatta accagatact gcaaagagtc actgacaacc
    69481 ttttctaatt ctggcttttg tgtataactc tctttatata agtctaagat tcgtttcgtt
    69541 actctctcat gatgatctgc tctctttctc attatatcaa tattcatact ctgatcagct
    69601 cttcccaata agtactgata aatatccaac ttaaaataaa tataattttc tacaaattgg
    69661 agggggagca ttgtatactc ttggtcgaca taaaatgtat tttcactaat cgtaatagca
    69721 ttatccttca agatacttgt tttatagacc agggcatgca taggtgtcca cttgctagga
    69781 atacctcttg tctcttgatt tggaattaga taagaagaga attctttaaa aatagtgcta
    69841 ttattatata catgctgctc tgtatagtca gaaatcacta aatcagtgtt aatctctctt
    69901 aacttatcca ataagctttc aaattcttga acattgatcc aatcatcccc atcaatgacc
    69961 ttaaaatatt ttccattagc ttctttaatc ccgcgattaa tagttgagcc atggccccca
    70021 ttttcttttg tgataattct taaatctaaa gtgctacctt ccattaaatc cttaacaact
    70081 tgtacagaat tatcagtact tccgtcatta atgattaaca cttcaaaatc actgtaataa
    70141 gcaggattta cagctttaaa tgattctatg catttaccaa tatagttttc aatattatag
    70201 gttggcacag taatcgtcag tattttatta gacattttcc cccccagata cttcttctat
    70261 caaatctatc cactgatgta taattcggtc tttattaaat tttttaatgt tatcttttgc
    70321 atgagatgaa aaacgatttc ttagctcctt atcattcatt agttctaata atctattaga
    70381 catcgcttct acatcataac actcaaccag atagccatta actccatctt caacaatttc
    70441 gttcggtcct gtcggacaac taaagctagc tataggaaga ttgtattgtt gtgcttccag
    70501 caggactaaa ggtagacctt catagcgaga agtcatgaca taaatccctt tatctccata
    70561 aatcaaatct tgattttttt cgagtccttt tatgactaac ctatcctgta aatcattttc
    70621 gttgattaaa tctctgattt tatctacttc atcttgattg ccggaaccgt agatttccca
    70681 agtccagtca gcccttttct ctaacacttt tttcgcgact tgaatgagat aatcatagcc
    70741 tttttgataa tcaaaacggc caacagtcac aattttagtt gattttttat tataagatac
    70801 atctgaaaga gcagcctctt tccaattata gatgtagcaa attctttcct caggaacacc
    70861 gtattttttt atataatttt cacggtcttc ttgagtgaga gtgataatct tgtctgccaa
    70921 ctttgtccca acatatcttt ggaatttctg agaaaattct ctattatccg taatcgaatt
    70981 ggtatgatca cacaaaacta ctttagtttg agttcctatt cctgccaaag ataaaaatac
    71041 attagcagat atccctatcc caaaaccaac ctctatttca ttatctatga aatattttct
    71101 taacattttt gagattttta gaatattctt agacaagcgt actctatggt caaaaaaatt
    71161 ggagtatctt acttgagaat tgattttaaa gaacaggtcc gattgctttg ttgtaattcc
    71221 aattaaatga acttcatact tttttgtaag ttcgtttgcc aaagatacag caactcgctc
    71281 accgccacca gaatcatcca aaatccattt cacaatacat atttttttcc caatttctat
    71341 cctacccttc actctgcatc acctactgat ataagttcta tattatgtgc tactctatct
    71401 tctactgatg gtaatttcat gtaatcaccg tagatttcgt ttaaatattc cttgtacttt
    71461 gtcggacagt ttatcatcgt atcctcaaaa ataagagaaa caggttcttt aaaatactct
    71521 ctcggaacta tttctctctc cctatatcta cctagaacat taccgacgta acgagaagtt
    71581 ttaaaatcat atttttgaat aactttatgc agattttcta ccaatgtatc cttaggaagt
    71641 actttttgga ttcttagcat tttcgatatt ttaactataa gattctccac agtgccacgg
    71701 tctttatctt caagctggtc taaaactgat attttacaaa gcattctttg aaacaatagc
    71761 ctaaaactat gcaatttagc tgcaaaaaat cctttttctg gataaccatc tagaggaaaa
    71821 atgtcaataa acacattgct ttccgaattc gcaattttaa caataacatt tttatctact
    71881 aactgagtta tatcaagatt aagtggatta ttaactattt ttaaattact tgctaacagg
    71941 tttggagcta gtattttaaa cttttcataa tcttctcttg gcataccgat atcaatatcg
    72001 tcatcccaag gtatgaatcc tttatgacgt accgcgccca acaaggtccc acctagagca
    72061 tagtaggtca ggttattttc ttcacaaata ttagtcaaaa ccttaagtaa ttctaattct
    72121 ttagattgaa tcttatataa ctttgtatct tcttccattt actattctcc acctttttta
    72181 gataaattac caatttgcat agctttcaac tattttttat acttaaaaac aatattttgt
    72241 tttattatcc agactaaagt ggcactagtt attaaaaaac gtaaaaaacc aactgttaat
    72301 atactttcaa aaaatcgatt tgaaaaaatc aacattataa catcattaaa caaataagca
    72361 tagataaata acttataatc aaataaatat ttttttgcac aatattctgt acccaatatc
    72421 ctactataag ttggaacaaa atataatgca attacagata ctaatggaat aatgccgaaa
    72481 taagtgaagt cataaaaaaa cgtataaaaa gttgtaaaga cattccctgt aggcaatcca
    72541 ttggtactct tcacaaaaga atcactacca ataatacttt taatattaaa atctatcaag
    72601 tgtagtttac tatacaagaa tttataaaag ccataaaaag tctgttctcc ccaatatact
    72661 gagtcacttc tatacggatc atgtccagca ataaaattgt taaaatttaa taacggagcg
    72721 ccaatgtact tgaatagttc tcgattaaga gcttcaataa tcccatcttg acctactcca
    72781 ccggaacgcc ccgttgcatt taaataaagt acaaatagag gagcaactgc cactacaaca
    72841 ataaggacct taaaagcaaa gcgagaactc aatttactaa gtcctttatt acgcagtagt
    72901 aaaatataaa aaacaactaa tataaaagtc aaaattttaa acaaggaccc tctactacca
    72961 gtcataaaaa tttgaattgc aaataaacaa ggaactagga gttgaaattt atctattctt
    73021 cttgttgcca cataattgtg acaaataatg tatataatca cgtaagaaat aggagatatg
    73081 aagctattaa acactctata aaaaaacgga gacctgaccc ccaatccgac taagtcttca
    73141 gtaaaaaact ttactaattg gtcatagtta ttaattattt gcgagaaact tccacgaccg
    73201 ccaacataag cgctgaataa agcttgttcg tatcgataaa agaaaataag atttaaaatc
    73261 tgaataataa ttattgtaaa aattagactt ttactgacat atagatattt taatttattc
    73321 ttaaaggtga aagtattagt cttaaatatt ttctttgata atactgttat tattgtaaaa
    73381 acgagcattg aaatcgtcac aataaaaact gtacctccat tgaactcaat agcatactct
    73441 tgagcattta aaatgcaaaa cagtgttgct atcaaaaaag taaagttaaa gataattgtt
    73501 gggtgaaaat aatctcctct tacaaaagca taatttataa taaaaaataa taataataaa
    73561 taaaataata tataaagcat ctacattcct tcaagtatta atactcttaa ctacaaaatg
    73621 tttatttact aaacatatag aattcggagt atataattta ataagtgctc ttaaaaactc
    73681 tgtccatact tctttccaaa aaatttagcc attaaaaaag attttccttt ttcaaacaaa
    73741 tgcactctct ccatgtacat aaatggtacc tctttaggcg ttattccttt tttacataac
    73801 caaacattaa acaacaactc actaactcgc ccgaataaac gtgactcaaa tggagtatag
    73861 tcggtcaagt ccatctgttc gtacatagta tccagaatag aaaaaagcca cggtaaataa
    73921 tcatctaata gttctttttt catgataaac atattgaaca tataacctct tctttgtttc
    73981 atcactttat caaaggatga aagatactct gaactatttt gctcaataat tttcctagca
    74041 agatccagat gttctccatt aagggtatgg gcataatgtg aataaagagt ttcaatataa
    74101 tactttcgct tctttggaac tattatgtca gatttctcta ataatatttc aacattagat
    74161 cgagacaaaa tgacgtcatc catattgaca ttttcattat acccttgaga tttatttgta
    74221 aaataacgac ggtaatgaac taaacctaag taattataat caagattctt ccatgcccaa
    74281 taaagtcccg tcaactcaca ataatatgga tttagagagg atatattatc gccagtatta
    74341 tcaccgataa aaccaatatc tgatttaccg tctctcccaa catgtattgg aaggtaaaga
    74401 ctactgtctt gaggcatttt aacctcttta tgtgttgcca caatgatttt tacatctatc
    74461 aatctacttc gctccatcct tcatcaatac aactttaact gtcttcaata aaatctcaat
    74521 atctttccaa attgtccaat cgtctatata ggctacatct aatttgacaa cttcatcaaa
    74581 attcttaatc tcacttcgtc cactgacctg ccataagcct gttataccag gtttaaaact
    74641 tagccgacgt ttttgttctg gggtatagtg ttcatactcg tccactgttg gtggccgtgt
    74701 gccaaccaaa ctcatatctc cctttagaac attataaaac tgtggtagct cgtccaagct
    74761 agtcttccgt ataaaacaac caattttcgt gatacgagga tcatcgtcca ccttaaacat
    74821 tccaccttgc atggtatttt gttccatgag ttctcttttt ttcgcctcgg catctacaca
    74881 catagagcga aacttataaa aagtgaactg acgaccattt tttcctatac gcgtctgagc
    74941 aaaaatagca gatcccccat cctttcgaat caaaggaacc agtacaatac tgactaaacc
    75001 acatagtatc agccctacca atgcacccac gatatcaata atccgcttag caattacatg
    75061 actagtctta taaaatgttg tagaaaaagt cacaacgttt aaccctgcca tctcacgaat
    75121 ttgcttgtta cgtgccaaac tacgatcaaa agcatttaga ttgactgtta catcaattcc
    75181 catcgtttca aactgagaga caagctctcc aatattgtat ttttcacttg gaagattgat
    75241 aaagacttca tcgaccacct catgagtcgc aaagtttact atctccccct ctgctactac
    75301 ctttaaacaa tcatgctgaa aatctggttt atctaagaca ctgacggcta ccaacttccc
    75361 aacaacctca tttgattcta ttaatctatc cagtaccttt tcgacacgag aagttgctgt
    75421 aagtaggaga atcttcttac ttcctttaaa gttgggataa gcccgcttcc aataccactt
    75481 gataaatagg tttagcacat agactaagag agcatgtaat gtgaggaagt aaatcatgcc
    75541 tcgtctggaa atactaaatc gatcctctaa gaaaaaatta gaaatactaa tcgctagtgc
    75601 aaagaatagg atatatttca atgtctggac aagttcaatc aaatatctcc ttttaaagaa
    75661 atcctgtcca taatcactga tataaaagac aaaataatgg aggatataaa gtgcaatagc
    75721 tgttgttgaa acaatctccg tttctctcac agcactaagt agataagtca ataaaataac
    75781 aagaaaactc tggattatgg ccaatgaagg ctttactatt tttccattca tctctatccc
    75841 ccgacctatt ttttattttt cccgtaatct ccataatctc cataagaacc gtatttgtct
    75901 actgaagtat cgaatttatt caacacaatt cccaaaaacg gctttcctgt gtgttccaac
    75961 tgttcttttg ctttttgaat atcccgacga tttatttcac ctgcctccgt cactaaaata
    76021 gaagcatcgc agtttcgcgt aataatagcc gcatcaatca cgacaccaac aggagcagta
    76081 tctacaatga tgtagtcaaa atatttacgc aaggtttcaa gcattgtagt gaaattctta
    76141 ctttgaagaa gagctgtcgg attcggtgac acagagccag cctgaattac aaagagattt
    76201 tcgatattgg tatcacaaag cccttgtgat aggtctgtag ttcctgataa aaattctgtc
    76261 aggcctgtaa tcttattcct tgctttaaag acacctaaca taacagaatt gcgaatatct
    76321 ccatcaatca gcagcgtttt gtaacctgca cgcgcaaaag cccaagcgat attggcggaa
    76381 gtcgttgatt ttccttctcc tattttcaca gaagtgatag aaaatacttt caaaccatct
    76441 ccacttaact gtaggttcgt gcacaaagcg ttataatatt cctctgcctt ttttacagaa
    76501 tccaattttg cctgtgagat ttctaatgtt ggcataactt cctcctattt tattttgtta
    76561 aaatctggaa cgagccctaa aagtggaatt ttcagtacat cttcaacatc ttcaggacgt
    76621 ttcacacggg tgtcgagcaa ctcaatcaaa agaacagcaa ttactgttac gactgctcct
    76681 ccaagaaaac caaacaagga attgcgtcga acatttggag aagagggagt tgtagctggt
    76741 cgcgcttctt caagtgtcgt tacatcagat actcgcgtta cagcgacgat cttttctgca
    76801 gcaacttctc gtagaaaatt agcgatacga ctggcttcct ctggctgttt atccttgaca
    76861 gagattgaga cgatacgagt gtcagctggt acagtcactt gaactttgct ggctaacgtt
    76921 tttgctggca tatccaactt caaatttgtc actacttttt ccaatacatc ctgcgaaagg
    76981 acaatctcac ggtagtcttt taccagataa gatcctgcct gcaaatcctg atttgtcagc
    77041 cccggcttgt ctccttgatt tcgattcact acgtaaattc gcgtggtact cgtatattct
    77101 ggcttaacaa taaaagtgct atatgcaaaa gcccccgcac ctgtcacaag tgccactaat
    77161 aaaatcatta gcttgcgttt ccacaaggtt ttaactaatt gaaatacatc gatttctgtc
    77221 gtgttttgtt ctttcatcat ttctcctaaa ttagttgatc cattacaatt cttcgaggat
    77281 tgtctataaa aagttcctga gccttcgctt ctccgtattt ttgggtaaca aggtcatatg
    77341 cttctgccat atgaggaggt ctactgtcta gattgtgcat atcacttgca atgacatgaa
    77401 ccaaatcctg ctctaaaaaa tactgaactc tttttttcat gaatttataa cgttcgccaa
    77461 aaagtttggg tttgaggaca tgtgaactat ttacttgcgt gtaacagccc atatcgatca
    77521 gttcccgaac gcgtttttca ttattttcaa gagcatcata gcgctcaatg tgggcaatga
    77581 ctggagtaat tcccaacatc aagatcttgc tcaaggcgct atgaatctca cgataggaag
    77641 tatgcatgct aaactcaatc aaagcataac gactatcatt gagggtcgga atccgctttt
    77701 tttccagctt atccagaaca tctggtgtgt agtaaatttc agccccgtaa gcaatgacca
    77761 agtcactcgc cacttcctta gctatttccc gaacctgaag aaagttttct gctatcttct
    77821 cttccggagt ttcaaacatg cccttgcgac ggtgagaggt agagacaatg gttcgcaccc
    77881 cctgtctgta ggcttctgcc aagagagtct tgctttcctc ccttgacttg ggaccatcat
    77941 ctacatcaaa gacgatgtgc gaatggatgt ctatcatttc atctaccctc catcacatcc
    78001 tgtatagctg ctttaactac agctaaacta ctatcatcta tttccatcac atagaggtta
    78061 ctgtctggca ttgcataaga aggaagatcc gtccgacctg taccttttaa atcttgagaa
    78121 tttactttat aattccctcc actttctaac tgagcattga ccaaatttat catagtctca
    78181 agtggcatat ttgtttggat agaatcttgc aagctattaa tgatcgtact ataatttttc
    78241 agtgcttcgg ttgacgttaa tttttgaagg atagccacaa tcaccttttg ttggttgcga
    78301 ccacggtcac gatcgccatc tgctagggag tagcgctcac gaacaaaacc gagagcctgt
    78361 tctgaatcaa gatgaacatt gcctgcagga taatactttc cattcgtatg ggcagtaaat
    78421 tcttgatcat tataaacatc aattccaccc aacaaatcaa tcaatttcaa aaatgaggta
    78481 aaattcaaac gaacataata attaatatct acaccataaa ggttctctag ggtatgaatg
    78541 gacgaatcaa ctccataaat gcccgcatgg gttaatttat ctttttgatt atttccacca
    78601 tctgcgattg gtacataggc atcacgtggc gttgtggtca agaggatttt cttggtatct
    78661 cgattgacag tcatcaggat attgacatct gatcgcgaca ccgaactaat aggaccatag
    78721 gtgtcaattc cactaacata gatattgaaa gactgattct tagacgtctt aggagcttct
    78781 acttttttag tgaatccctt ggtataaatc ttctttatct tcgatgcgta gtctggatac
    78841 tctgactcga tgatattttc aaagacacta tttaggacaa tggccttagt ctcccctgca
    78901 atcaaactct tgtaagctgc caagtaagac gaactctggt tgaccgtcaa atcggtattc
    78961 tgacttgact tgatatcagc tagtagtttt tgaatatttt cgttatcagt cccagtcggt
    79021 gctgtcacac tcgtcagttg cgtaacattt tcgatctcac tatctgctaa aacagcgaca
    79081 ctgattgaat attctgagta attcgaagtc gcatttaaac gattggtcag tccaacaaac
    79141 tgctgtactg caaagagcga cacagagctg gcaaggatag agaacaccaa cagaaaaata
    79201 gtaaactttt cagctttttt atagataatc aagagtagcc ctaccaaggc aactagtagg
    79261 actaacgcag ttaccactag attaagatat ctaaaagcaa ggatattgta cttaaagatt
    79321 aagaacaata aaaaacaaac taacaataaa taaatagtca gcaaaacgat actaacactt
    79381 cgcttcactt tctgtgaacc tgatttttta aaacgtctac tcatgattaa cacctataca
    79441 ttgaacatca tacgattata tcactttttt acggtaatgt ctacatcttt ttttactatc
    79501 tgcatcttta aatatcttag tagacttccc gcgaaccaaa aatatagtaa aatgaaataa
    79561 gaacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagcagag
    79621 gtggactatt ctagtttcaa tctac
//
LOCUS       DAVHBD010000003        66586 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000003 DAVHBD010000000
VERSION     DAVHBD010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.003"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(202..561)
                     /locus_tag="VVK04_000196"
     CDS             complement(202..561)
                     /locus_tag="VVK04_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU3988913.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            653..1609
                     /locus_tag="VVK04_000197"
                     /pseudo
     CDS             653..1609
                     /locus_tag="VVK04_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            1593..2150
                     /locus_tag="VVK04_000198"
     CDS             1593..2150
                     /locus_tag="VVK04_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU3988914.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            2143..2397
                     /locus_tag="VVK04_000199"
     CDS             2143..2397
                     /locus_tag="VVK04_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988915.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            2409..4463
                     /locus_tag="VVK04_000200"
     CDS             2409..4463
                     /locus_tag="VVK04_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU3988916.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            4642..5502
                     /locus_tag="VVK04_000201"
     CDS             4642..5502
                     /locus_tag="VVK04_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU3988917.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            5713..6423
                     /gene="ccdA2"
                     /locus_tag="VVK04_000202"
     CDS             5713..6423
                     /gene="ccdA2"
                     /locus_tag="VVK04_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU3988918.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            6443..7009
                     /locus_tag="VVK04_000203"
     CDS             6443..7009
                     /locus_tag="VVK04_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU3988919.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            7020..8132
                     /gene="msrB"
                     /locus_tag="VVK04_000204"
     CDS             7020..8132
                     /gene="msrB"
                     /locus_tag="VVK04_000204"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU3988920.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            8355..9092
                     /locus_tag="VVK04_000205"
     CDS             8355..9092
                     /locus_tag="VVK04_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3988921.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            9089..10780
                     /locus_tag="VVK04_000206"
     CDS             9089..10780
                     /locus_tag="VVK04_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU3988922.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            10896..11459
                     /locus_tag="VVK04_000207"
     CDS             10896..11459
                     /locus_tag="VVK04_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU3988923.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            11481..16949
                     /locus_tag="VVK04_000208"
     CDS             11481..16949
                     /locus_tag="VVK04_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU3988924.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKSAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNSKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETVNQPVEQPKVETPAVEKQTEPTEEPKVEVTTVETREEVIPFETKE
                     QEDDTLKRGTRQVVQKGVEGKKQITETYKTIRGEKTNEAPIVKETVIEQPQDEIIKKG
                     TKGLEKPTLQWANTEKDVLKKSATASYTLTKPAGVEIKSIKLALKDKDGQLVKEVTVA
                     ENNLNATLDKLKYYQGYTLSTTMVYDRGEGEETEKLEDKQIQLDLKKVEIKNIKETSL
                     MNVDAEGNETDKSLLSEKPTDVSQLYLRVTTHDNKVTRLAVSSVEEVVVDGKTLYKVV
                     AKAPDLVQRRADDTLSEEYVHYFEKQLPKVNNVYYNFNELVKDMQANPTGEFKLGADL
                     NAANVKPNGKSYVTKPFKGKLLSNDGGRFTIHNIERPLFANIEGGKIHDINLANVNIN
                     MPWADKVAPIANVIKNNATIENVKVTGNVLGKDWVSGFIDKIDGSGKLINVAFIGNVT
                     SVGTGGNFLTGIVGENWKGYVERAYVDAHIKGKRAKAAGIAYWSQNQGNNFTIGSEGA
                     IKKSVVKGTIDVEKPIEVGGAVGSFTYHGSIEDTVSMMKVKNGEIFYGSKDIDDDPYY
                     TGNHVNRNYVVIGVSEGTSTYRYSNQHNRIKPITQSEADVKIAETAITADKFTITDPI
                     VNKLNALTTRDNEYRTTQDYEATREQAYRNIEKLQPFYNKEWIVNQGNKLVEGSNLLT
                     KEVLSVTGIKSGQFVTDLSDIDKIMIHYSDGAKEELNVTRQESNVQQVREYSITDLDI
                     LYTPNMVEKDRAQLMTDVKSKLSSVELESDGVRQLLVKRDTKKDANANSVGRQNGYIR
                     DLFLEESFSEVKANLDKLVKQILENEDHQLNDNELAERALLKKVEDNKAKIMMGLAYL
                     NQYYAFKYDELSIKDIMMFKPDFYGKTASVIDRLINIGSAENNLKGDRTQDAYRGIIS
                     GATGKGSLHDFLTYNMKLFTNETDINVWFKKAIEKNAYVVEQPSTNPAFANKKYRLYE
                     GINNGQHGRMILPLLNLKNAHLFMISTYNTISFSSFEKYGKDTDEKREKFKSEINKRA
                     KEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHNSPNGWASRHGHIDGKPDYAP
                     IREFFGRINKYHGYKYGYGAYAYIFAAPQPMDAVYFVMTDLISDFGTSAFTHETTHVN
                     DRMAYYGGHWHREGTDLEAFAQGMLQTPSVSNPNGEYGALGLNMAYERQNDGNQWYNT
                     NPNDLTTRAEIDNYMKGFNDTLMLLDYLEGEAVLNKANQDLNNAWFKKVDKQLRGAST
                     KNQYDKVRDLTADEKNITLNSVDDLVDNNFMTKHGPGNNVYDPTGFGTAYVTVPITAG
                     IYGGNTSEGAPGSMSFKHNTFRMWGYYGYEKGFLNYASNMLKNESRQAGHNTLGDDFI
                     IKKVSDNKFSTLEDWKKAYFKEVVDKAKAGFNPVTIDSTTYSSYDDLKNAFAAAVEKD
                     KATLKNGSVKSDNTVALKEKIYKKLLQQTDSFKTSIFK"
     gene            17010..18731
                     /gene="pabB"
                     /locus_tag="VVK04_000209"
     CDS             17010..18731
                     /gene="pabB"
                     /locus_tag="VVK04_000209"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU3988925.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEGLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            18732..19349
                     /locus_tag="VVK04_000210"
     CDS             18732..19349
                     /locus_tag="VVK04_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU3988926.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTYPYPTLLICGSKDKPNL
                     SFMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            19399..20396
                     /locus_tag="VVK04_000211"
                     /pseudo
     CDS             19399..20396
                     /locus_tag="VVK04_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            20523..21482
                     /locus_tag="VVK04_000212"
     CDS             20523..21482
                     /locus_tag="VVK04_000212"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU3988927.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            21579..22418
                     /locus_tag="VVK04_000213"
     CDS             21579..22418
                     /locus_tag="VVK04_000213"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU3988928.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(22466..22636)
                     /locus_tag="VVK04_000214"
     CDS             complement(22466..22636)
                     /locus_tag="VVK04_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU3988929.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            22757..23641
                     /gene="miaA"
                     /locus_tag="VVK04_000215"
     CDS             22757..23641
                     /gene="miaA"
                     /locus_tag="VVK04_000215"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU3988930.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            23634..24872
                     /gene="hflX"
                     /locus_tag="VVK04_000216"
     CDS             23634..24872
                     /gene="hflX"
                     /locus_tag="VVK04_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU3988931.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            24865..25488
                     /locus_tag="VVK04_000217"
     CDS             24865..25488
                     /locus_tag="VVK04_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU3988932.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            25503..26432
                     /locus_tag="VVK04_000218"
     CDS             25503..26432
                     /locus_tag="VVK04_000218"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU3988933.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            26453..27208
                     /locus_tag="VVK04_000219"
     CDS             26453..27208
                     /locus_tag="VVK04_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU3988934.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(27262..28170)
                     /locus_tag="VVK04_000220"
     CDS             complement(27262..28170)
                     /locus_tag="VVK04_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU3988935.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            28234..28503
                     /locus_tag="VVK04_000221"
     CDS             28234..28503
                     /locus_tag="VVK04_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU3988936.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            28503..28883
                     /locus_tag="VVK04_000222"
     CDS             28503..28883
                     /locus_tag="VVK04_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU3988937.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            29001..29198
                     /locus_tag="VVK04_000223"
     CDS             29001..29198
                     /locus_tag="VVK04_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988938.1"
                     /translation="MGILSIILGLLFPIVGLILGIIGLVLAISYQKESQLDYKIEKIL
                     NILGIVISVVNWIVAIALIFR"
     gene            complement(29238..29963)
                     /locus_tag="VVK04_000224"
     CDS             complement(29238..29963)
                     /locus_tag="VVK04_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEU3988939.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            30125..31966
                     /gene="typA"
                     /locus_tag="VVK04_000225"
     CDS             30125..31966
                     /gene="typA"
                     /locus_tag="VVK04_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU3988940.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            31986..32240
                     /locus_tag="VVK04_000226"
     CDS             31986..32240
                     /locus_tag="VVK04_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU3988941.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            32604..32903
                     /locus_tag="VVK04_000227"
                     /pseudo
     CDS             32604..32903
                     /locus_tag="VVK04_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            32974..34995
                     /locus_tag="VVK04_000228"
                     /pseudo
     CDS             32974..34995
                     /locus_tag="VVK04_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            34997..35638
                     /locus_tag="VVK04_000229"
     CDS             34997..35638
                     /locus_tag="VVK04_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3988942.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKSSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            35742..37094
                     /locus_tag="VVK04_000230"
     CDS             35742..37094
                     /locus_tag="VVK04_000230"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU3988943.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMAAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            37098..38156
                     /locus_tag="VVK04_000231"
     CDS             37098..38156
                     /locus_tag="VVK04_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU3988944.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            38166..39386
                     /gene="divIB"
                     /locus_tag="VVK04_000232"
     CDS             38166..39386
                     /gene="divIB"
                     /locus_tag="VVK04_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU3988945.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKKQEE
                     ESNRNQTNQRSSRR"
     gene            39619..40320
                     /gene="pyrF"
                     /locus_tag="VVK04_000233"
     CDS             39619..40320
                     /gene="pyrF"
                     /locus_tag="VVK04_000233"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU3988946.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSVMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            40354..40986
                     /locus_tag="VVK04_000234"
     CDS             40354..40986
                     /locus_tag="VVK04_000234"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU3988947.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            41166..41569
                     /locus_tag="VVK04_000235"
                     /pseudo
     CDS             41166..41569
                     /locus_tag="VVK04_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            41665..42429
                     /locus_tag="VVK04_000236"
     CDS             41665..42429
                     /locus_tag="VVK04_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988948.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            42429..43181
                     /locus_tag="VVK04_000237"
     CDS             42429..43181
                     /locus_tag="VVK04_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988949.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTAILFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLALLSIIIPLTVFSVHRNWRRV"
     gene            43191..43889
                     /locus_tag="VVK04_000238"
     CDS             43191..43889
                     /locus_tag="VVK04_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988950.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAIVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            43886..44533
                     /locus_tag="VVK04_000239"
     CDS             43886..44533
                     /locus_tag="VVK04_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3988951.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRELSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(44620..45491)
                     /locus_tag="VVK04_000240"
                     /pseudo
     CDS             complement(44620..45491)
                     /locus_tag="VVK04_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(45503..46261)
                     /locus_tag="VVK04_000241"
     CDS             complement(45503..46261)
                     /locus_tag="VVK04_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU3988952.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDILLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKAQGRDKKEVTEEALQLLERVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(46262..46939)
                     /locus_tag="VVK04_000242"
                     /pseudo
     CDS             complement(46262..46939)
                     /locus_tag="VVK04_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
     gene            complement(46899..47567)
                     /locus_tag="VVK04_000243"
     CDS             complement(46899..47567)
                     /locus_tag="VVK04_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU3988953.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILI
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            47793..47939
                     /locus_tag="VVK04_000244"
     CDS             47793..47939
                     /locus_tag="VVK04_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU3988954.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            48067..49557
                     /gene="lysS"
                     /locus_tag="VVK04_000245"
     CDS             48067..49557
                     /gene="lysS"
                     /locus_tag="VVK04_000245"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU3988955.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            50182..51318
                     /gene="lctO"
                     /locus_tag="VVK04_000246"
     CDS             50182..51318
                     /gene="lctO"
                     /locus_tag="VVK04_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU3988956.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      51572..51660
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            51875..52543
                     /locus_tag="VVK04_000247"
     CDS             51875..52543
                     /locus_tag="VVK04_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU3988957.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(52693..52779)
                     /locus_tag="VVK04_000248"
                     /pseudo
     CDS             complement(52693..52779)
                     /locus_tag="VVK04_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            52870..53652
                     /gene="thiM"
                     /locus_tag="VVK04_000249"
     CDS             52870..53652
                     /gene="thiM"
                     /locus_tag="VVK04_000249"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU3988958.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            53654..54283
                     /locus_tag="VVK04_000250"
     CDS             53654..54283
                     /locus_tag="VVK04_000250"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU3988959.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      54492..54580
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54842..55402
                     /locus_tag="VVK04_000251"
     CDS             54842..55402
                     /locus_tag="VVK04_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU3988960.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            55403..56788
                     /locus_tag="VVK04_000252"
     CDS             55403..56788
                     /locus_tag="VVK04_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3988961.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAAMAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRELTSIVQEAEKQFIRVSLREELRLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            56790..57440
                     /locus_tag="VVK04_000253"
     CDS             56790..57440
                     /locus_tag="VVK04_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU3988962.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            57451..58143
                     /gene="tenA"
                     /locus_tag="VVK04_000254"
     CDS             57451..58143
                     /gene="tenA"
                     /locus_tag="VVK04_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU3988963.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            58148..58672
                     /gene="thiW"
                     /locus_tag="VVK04_000255"
     CDS             58148..58672
                     /gene="thiW"
                     /locus_tag="VVK04_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU3988964.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFHYSALGE
                     ILGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            58672..59475
                     /locus_tag="VVK04_000256"
     CDS             58672..59475
                     /locus_tag="VVK04_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU3988965.1"
                     /translation="MQEFTNPFPIGSSSLIHCITNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLVVSKNQVAVLGNGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            59468..60100
                     /locus_tag="VVK04_000257"
     CDS             59468..60100
                     /locus_tag="VVK04_000257"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU3988966.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLKKLHNILS"
     gene            complement(60310..61101)
                     /gene="thiD"
                     /locus_tag="VVK04_000258"
     CDS             complement(60310..61101)
                     /gene="thiD"
                     /locus_tag="VVK04_000258"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU3988967.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESIFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(61185..61283)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            61467..61862
                     /locus_tag="VVK04_000259"
     CDS             61467..61862
                     /locus_tag="VVK04_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU3988968.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     SRLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            61873..62244
                     /locus_tag="VVK04_000260"
     CDS             61873..62244
                     /locus_tag="VVK04_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU3988969.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            62254..64497
                     /locus_tag="VVK04_000261"
     CDS             62254..64497
                     /locus_tag="VVK04_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU3988970.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            64704..66479
                     /gene="spxB"
                     /locus_tag="VVK04_000262"
     CDS             64704..66479
                     /gene="spxB"
                     /locus_tag="VVK04_000262"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU3988971.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
BASE COUNT        20100 a        12081 c        14670 g        19735 t
ORIGIN      
        1 ctttctaaat ggtttattaa gcaattctat tttaccaaga ctatcgtaac catgcaaaaa
       61 agcaacggca aatccgttgc ctttttggat ataagagact attgtcccag actcttttct
      121 ttgtataaaa ttgtatagtg ttattgtcta tactattttg tagagaaagc aaaaatccct
      181 agaaaatgct tagggattcg actatttcat taagaacaat tcaacaatca tttctatata
      241 catgataagg gttaataaga atcctgcacg ccagaagaat ttgatgaatt taggatagta
      301 aaagctgcgt ttttttaaaa ggaagaaaaa gacgagaata atggctagga acgagagggc
      361 tagccccagt ctagggagga aattatgggt aaaggtttta gctgtaatca agtaatactc
      421 aaataccaag actggaaaag ccaaatccgc aaagtttcgt cctagttttt ttaatctaaa
      481 aagtttggtt aggataatgc agacgactaa ggtcagtatc aataataaaa tagatgctaa
      541 tttcattaaa atcataccca tattgtatca taaaaaaagg ctaatggaaa cgagaaacag
      601 aggaatttat aggaaagtca ggcttttgag attgtgggtg atttttgtta taatgaaagt
      661 tataaaatct tataatacct tgaatgatta ttatcgaaaa ctgtttggag aaaagacttt
      721 taaagtccct attgatgcgg gatttgactg tcccaatcgt gatggaactg tggctcatgg
      781 aggctgtact ttttgtacgg tttcaggttc tggagatgct attgtagccc cagatgcgcc
      841 tatccgtgag caattttata aggaaattga ctttatgcac cgtaagtggc cggatgttca
      901 gaagtatctg gtttattttc aaaattttac caacacccat gaaaaggtgg aagttattcg
      961 agagcgttat gaacaggcta tcaatgagcc aggtgtggta ggtatcaata ttggaacgcg
     1021 cccagactgt ttaccagacg aaaccatcga atatttggct gagttatcgg agtgcatgca
     1081 tgtgatggtt aaattgggct tgtagactac ttatgaagca acttctgacc tgattaaccg
     1141 tgcgcattct tatgaattgt aggtggaaac ggtcaagcgt ttgagaaagt atcccaagat
     1201 tgagattgtt tcccatttga tcaatggttt gcctggtgaa acccatgaga tgatggttga
     1261 aaatgtccgc cgttgtgtca cgaataacga tattcaaggg attaaactgc atttgctcca
     1321 tcttatgaca aatactcgta tgcaacgaga ttaccatgag ggacgtttac aattgatgag
     1381 tcaggacgaa tatgtcaggg tcatctgtga ccaactggaa attattccca aacatatcgt
     1441 catccatcga attacaggag atgcgcctag ggatatgctg attggtccta tgtggagcct
     1501 caaaaaatgg gaagtcctca acagcattga gatggagatg cgacgtcgtg gaagtgttca
     1561 aggatgcaag gttgtaaaac aggagtttga aaatgaaaag accacttgag atggcacatg
     1621 attttttggc tgaggtcgtg acaaaagagg atgtcgtagt ggatgcgact atgggaaatg
     1681 gtcatgacac gcttttttta gccaagctag ccaagcaagt ctatgccttt gatattcaga
     1741 agcaagcctt ggaaaagacc caagagcgtt tgcatcaggc tggcttgaca aatgcccagt
     1801 taatcttgca aggccatgag acactggacc agtttgtgac aaaagctaag gcagggattt
     1861 ttaatctggg ctatttgccg tcagctgata agtctgtcat cacccgaccg cagacaacga
     1921 ttgaggcatt agaaaagcta tgtggcttac ttgtcaaagg tggacgaatt gctattatga
     1981 tttactatgg tcatgaagga ggcgacctcg agagagatgc tgtcttggat tttgtgatcc
     2041 agttgaacca acaagagtac acagctgcca tttaccgaac tttaaaccaa gtcaacaacc
     2101 cgccgttttt agtgatgatt gaaaaattag agagatacag acatggataa acaataccta
     2161 cacgaaaagc tggatgccat gcgccagaat tttgttgaat caactcacca cgaacgagcg
     2221 gtgggcgtgc tagaccaagc gcatatgagc aaaaaaatgc ttaaaatcaa gaaaaaatta
     2281 gttgctcttg aaatggaacg gtgccagaga aaaattgagc acaaagactg ttccaagatt
     2341 gaccaaaaaa tcaaagagca gaaggagata tttgaatcct gttgtaaaaa agattaagga
     2401 ggacgtgcgt ggaattactg atttacctca tcctattttt actggttttg attgtctcaa
     2461 gtacaaccaa taagctcctg ccctttttgc ctctcccttt ggtgcaaatt cttttgggaa
     2521 ttgtgattgg tctcttttta cccaataccg actttcacct caatacggag ttgtttttgg
     2581 ccctggttat cggacccttg cttttccgag aggctgaaga agcagatgtt acggctattt
     2641 taaaacactg gcgaatcatt gtttatctca tatttccagt gatttttatc tcgaccctga
     2701 gtttgggtgg cttggcccat cttctttggt tcagccttcc cttggcagct tgcttggctg
     2761 ttggggcagc ccttggtcct acggacttgg tggcctttgc ctctctttcg gagcgtttta
     2821 gctttcctaa gcgcgtgtcc aatattctta agggcgaagg actcttgaat gatgcttctg
     2881 gtttggtggc ttttcaggta gctttgacag cttggacaac tggagctttt tctctggggc
     2941 aagctagcag ttcgctcatc ttttcaatcc taggcggttt tttaattgga tttttaacag
     3001 ccatgaccaa ccgcttcctc cataccttct tgctaagtgt gcgcgcaacg gatattgcca
     3061 gtgaactttt attagaattg agtttgcctc tagtgacctt ctttctggca gaagaagtcc
     3121 atgtttcagg gattattgcc gtcgtagttg ctggaatttt aaaggcaagt cgcttcaaga
     3181 aaatcacgct cctcgaagcc caagtggata cggtgaccga gacggtctgg catacagtga
     3241 cctttatgct caacggttct gtctttgtga ttttagggat ggagttggaa atgatagcag
     3301 aacctatctt gaccaatcca atctataatc ctctactttt attgctatct ctcatcgccc
     3361 ttacctttgt cctctttgtc attcgtttta ttatgatcta tggctattat gcctatagaa
     3421 cccgacgcct caagaaaaag ctaaataagt atatgaagga catgtttctc ttgacctttt
     3481 caggtgttaa gggaacggtg tcgattgcta cgattctctt gataccaagt aatctagaac
     3541 aggagtatcc tctcttgctt ttccttgttg caggtgtgac gcttgtcagc tttttaacag
     3601 gtctcttggt cttgcctcat ctttctgatg aagaggaaga aagcaaggat tatctcatgc
     3661 atatcgccat tttgaatgaa gtaacgctag agttggaaaa agagttggaa gacaccagaa
     3721 ataaacttcc cctctatgcg gctattgaca attatcatgg acgtattgaa aatctcattt
     3781 taagccaaga aaaccaggat gatcaagaag actgggctgc tttgaaactc ttgattctta
     3841 gtattgaaag tgatggtttg gaacaggcct atgaagaggg gaacattagc aatcgtgctt
     3901 accgagttta ccaacgttat ctgaaaaata tagaacaagg aatcaatcgt aaacttgcct
     3961 caagactgac ctattatttt cttgtttcct tgaggatttt acgttttctc cttcatgaag
     4021 tttttactct tggaaagacc ttccgtagct ggaaggacaa ggagcaaagc cgtctccgtg
     4081 ctcttgatta tgaccaaatt gcagagctct atcttgccaa tacggagatg attattgaaa
     4141 gtttggaaaa cctgaaggga gtctacagac gctctttgat tagttttatg caggagtctc
     4201 gtcttcgaga aacagctatt atcagcagtg gtgcctttgt cgaacgggtt atcaatcgtg
     4261 tcaaacccaa caatatcgat gaaatgctga gaggctatta tctggagcgc aagttgattt
     4321 tcgaatacga agaaaaacga ttgattacga ctaagtatgc caagaaatta cgacaaaatg
     4381 taaataactt agagaactat tccttgaagg aagctgccaa taccctaccg tatgatatgg
     4441 tggaattggt aagaagaaat tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc
     4501 gtcgccttac cgtatgtatg tgactgactt cgtcagtctt atctacaacc tcaaagcagg
     4561 gctttgagca gcttgcggct agctttctag tttgctcttt gattttcatt gagtataaga
     4621 ttataagtga aggagtatga catgaaaaag tggtggaaag agctgataga caaaccttta
     4681 ttaaaagctt ttttgcatta ttatcaagca tcagatagtg agttgaccag tgtcgcagta
     4741 gcctactatt ggttgatttc gattttcccc ctgcttttgg tggtggtcaa tatcctcccc
     4801 tattttcaga ttcctgtggg agaatttctg ggctttatga aagacgttct gcccccaagc
     4861 ctctatgaag gtgtggaaaa aatagccaga gaagttttga cgcaaccttc aacaggttta
     4921 ttgagttttt ctgttttatc ggcgttatgg agtttttcaa aatctatgaa tttcttgcaa
     4981 aaagctttta acaaggctta tggcgtcgaa aagagtcgtg gacttatttc ccatcagatg
     5041 ctaagtctcc tagtcagttt tggcttgcag ctcctctttg cgtttgcctt gtttttgatc
     5101 ttatttggtc agatgatttt ggctttactt gctcattatt ggacaaaaga tggcattatc
     5161 tatcaggctt tacaagggtt ggcaggtcct ctgatttacg ccctcctctt tgctatcttg
     5221 gtcatgcttt attattttct tcccaatata tctaacagga aaattagcta taccctacca
     5281 ggcagtgcct ttgttctctt agtgatttta ggtttactaa ctctgttctc tagttatctc
     5341 aattactatg tccatcattt ggtggatgtc cgaattttag gttccgttct tcttgttgtt
     5401 atgatgtttt ggtttatctt gattgctaaa attgttatcc taggcgcggt tatcaatgcc
     5461 agtatgcaga gtttgaaaga tccggtcttt aaaaaagact aactatttat ctattataaa
     5521 agcgcatagt atcaagactt tatagaacct tgatactatg cgcttttgtg ctttgacagt
     5581 tttttgtata gtttttgtcc aagatttcta aatcatctga ttaaattcct attttcccct
     5641 atcattgtcc ctgttttttc gaaaatggaa ggagtataat aaatctatca ataaaatgat
     5701 aggaggaact ttatgggtca tattttcttt tttctaagtg tctttttggc agggattcta
     5761 tccttctttt ctccttgtat cttacctttg ttaccggtct atacaggggt gttactagat
     5821 gataaggatg gtgctcaggc ttctagcggc aaattttcaa tctcagttac tagtttatta
     5881 cgaactctgg cctttatagc aggaatttcc tttatattta ttttgttggg ctatggagct
     5941 ggttttttag gcgatttgct ttatgcttct tggttccaat atcttactgg ggcaattatt
     6001 atccttcttg gtttgcacca aatggagatt ctacacttta aggggcttta taaggaaaag
     6061 aggctacaac tgcaaggaca ggggcaaaat ggtaagggct atagtcaggc atttttattg
     6121 ggcttgacct ttagttttgc ttggacgcct tgcgtggggc cggttctagg gtctgttttg
     6181 gccttggcgg cttcaggtgg ttcaggagct tggcagggag ctggtctcat gttggtgtat
     6241 acgctgggct tggcgctacc attcttgctt ctagctctga cctctagtta tgttttgaaa
     6301 catttccgaa aacttcatcc ctatctcgga atcctcaaaa aagtgggtgg ttttctcatt
     6361 attgtgatgg gactcttggt tctgtttgga aatgcttcaa ttttaagtca attatttgaa
     6421 taaaatggaa aggaatatca atatgaaaaa atggcaaaca tgtgttcttg gagcaggttc
     6481 gctcctttgt ttgacggctt gttcaggcaa gtccgtgact agtgaacacc aaacgaaaga
     6541 tgaaatgaag acggagcaga cagctagtaa aacaagcgca gctaaaggga aagaggtggc
     6601 tgattttgaa ttgatgggag tagatggcaa gacctaccgt ttatctgatt acaagggcaa
     6661 gaaagtctat ctcaaattct gggcttcttg gtgttccatc tgtctggcta gtcttccaga
     6721 tacggatgag attgctaaag aagctggtga tgactatgtg gtcttgacag tagtgtcacc
     6781 aggacataag ggagagcaat ctgaagcgga ctttaagaat tggtataagg gattggatta
     6841 taaaaatctc ccagtcctag ttgacccatc aggcaaactt ttggaaactt atggtgtccg
     6901 ttcttaccca acccaagcct ttatagacaa agaaggcaag ctggtcaaaa cacatccagg
     6961 attcatggaa aaagatgcaa ttttgcaaac tttgaaggaa ttagcctagg aggtgtctta
     7021 tgaatgataa gttaaaaatc ttcttgttgc taggagtatt ttttctagcc ataaccggtt
     7081 tctatgttct attgatacga aatgcagggc agacagatgc ctcgcaaatt gaaaaggcgg
     7141 cagttagcca aggaggaaaa gcagtgaaaa aaacagaaat tagtaaagac gcagacttgc
     7201 acgaaattta tctagctgga ggttgtttct ggggagtgga ggaatatttc tcacgcgttc
     7261 ccggggtgac ggatgccgtt tcaggctatg caaatggtag aggagaaaca accaagtacg
     7321 aattgattaa ccaaacaggt catgcagaaa cggtccatgt cacctatgat gccaagcaaa
     7381 tttctctcaa ggaaatcctg cttcactatt tccgcattat caatccaacc agcaaaaata
     7441 aacaaggaaa tgatgtgggg acccagtacc gtactggtgt ttattacaca gatgacaagg
     7501 atttggaagt gattaaccaa gtctttgatg aggtggctaa gaaatacgat caacctctag
     7561 cagttgaaaa ggaaaacttg aagaattttg tggtggctga ggattaccat caagactatc
     7621 tcaagaaaaa tccaaatggc tactgccata tcaatgttaa tcaggcggcc tatcctgtca
     7681 ttgatgccag caaatatcca aaaccaagtg atgaggaatt gaaaaagacc ctgtcacctg
     7741 aggagtatgc agttacccag gaaaatcaaa cagaacgagc tttctcaaac cgttactggg
     7801 ataaatttga atccggtatc tatgtggata tagcaactgg ggaacctctc ttttcatcaa
     7861 aagacaaatt tgagtctggt tgtggctggc ctagttttac ccaacccatc agtccagatg
     7921 ttgtcaccta caaggaagat aagtcctaca atatgacgcg tatggaagtg cggagccgag
     7981 taggagattc tcaccttggg catgtcttta cggatggtcc acaggacaag ggcggcttac
     8041 gttactgtat caatagcctc tctatccgct ttattcccaa agaccaaatg gaagaaaaag
     8101 gctacgctta tttactagat tatgttgatt aatactcttc gaaaatctct tcaaaccacg
     8161 tcagcgtcgc cttaccgtat gtagggttac tgacttcgtc agttttatct acaacctcaa
     8221 agcggtactt tgagaaacct gtggctatct tcctagttta ctttttgatt tttattgagt
     8281 ataagaggtc tttcctaagc agttagagga gaattttgct atactgatac tagtaagtgg
     8341 taaaggagca gatcatgacc tacacaatct taatcgtaga agatgaatat ctggtaagac
     8401 aaggtttgac taaactggtc aatgtagcag cctacgatat ggaaatcatc ggtcaggctg
     8461 aaaatggaag gcaggcttgg gaattgatcc aaaagcaggt gccagatatc attttaaccg
     8521 atatcaacat gcctcatcta aatggcatcc agttggccag tctggtacga gaaacctatc
     8581 ctcaggttca tttggtcttt ttaacaggtt acgatgattt tgattatgcc ttgtctgctg
     8641 tcaaactagg tgtggacgac tacctgctca aacccttttc tcgtcaggat attgaggaaa
     8701 tgttggggaa aatcaaacaa aaactagaca aggaagagaa agaagagcag ttacaagatt
     8761 tattgactaa taggtttgaa ggaaacatgg cccagaaaat ccagtctcat ctggctgata
     8821 gccaatttag tttaaagtct ttagccagtg acttaggttt tagtccgacc tatctgagtt
     8881 ccttgattaa gaaagagttg ggcttgcctt ttcaggatta tctggtgaga gaacgtgtta
     8941 aacaagccaa gctcttgctt ttaactacag atctgaagat ttatgagatc gcagagaagg
     9001 ttggttttga agatatgaac tattttaccc aacgttttaa gcagattgca ggtgtgacac
     9061 ctcgtcagtt taagaaggga gaagaccgat gaagcgttct tctcttttag ttagaatggt
     9121 tatttccatc tttctggtct ttctcattct cctagctctg gttggaactt tctactatca
     9181 atcaagttct tcagccattg aggccaccat tgagggcaac agccaaacga ccatcagcca
     9241 gactagccac tttattcagt cttatatcaa aaaactagaa accacctcga ctggtttgac
     9301 ccagcagacg gatgttctgg cctatgctga gaatcccagt caagacaagg tcgagggaat
     9361 ccgagatttg tttttgacca tcttgaagtc agataaggac ttgaaaactg ttgtgctggt
     9421 gaccaaatct ggtcaggtca tttctacaga tgacagtgtg cagatgaaaa cttcctctga
     9481 tatgatggct gaggattggt accaaaaggc cattcatcag ggagctatgc ctgttttgac
     9541 tccagctcgt aaatcagata gtcagtgggt catttctgtc actcaagaac ttgttgatgc
     9601 aaagggagcc aatcttggtg tgcttcgttt ggatatttct tatgaaactc tggaagccta
     9661 tctcaatcaa ctccagttgg ggcagcaggg ctttgccttc attatcaatg aaaaccatga
     9721 atttgtctac catcctcaac acacagttta tagttcgtct agcaaaatgg aggctatgaa
     9781 accctacatc gagacaggtc agggttatac tcctggtcac aaatcctacg tcagtcaaga
     9841 gaagattgca ggaactgatt ggacggtgct tggcgtgtca tcattggaaa agttagacca
     9901 ggttcggagt cagctcttgt ggaccttgct tggggccagt gtcacatctc ttcttgtctg
     9961 tctctgctta gtgtggttca gtcttaaacg ctggattgct cctttgaagg atttgagaga
    10021 aaccatgttg gaaattgctt ctggtgctca aaatcttcgt gccaaggaag ttggtgccta
    10081 tgaactgaga gaagtaactc gccaatttaa tgctatgttg gatcagattg atcagttgat
    10141 ggtagctatt cgtagccagg aagaaacgac ccgtcagtac caacttcaag ccctttcgag
    10201 ccagattaat ccacatttcc tctataacac tttggacacc atcatctgga tggctgaatt
    10261 tcatgatagt cagcgagtgg tgcaggtgac caagtccttg gcaacctatt tccgcttggc
    10321 gctcaatcaa ggcaaggact tgatttgtct ctctgacgaa atcaatcatg tccgccagta
    10381 tctctttatc cagaaacaac gctatggaga taagctggaa tatgaaatta atgaaaatgt
    10441 tgcctttgat aatttagtct tacccaagct ggtcctacaa ccccttgtag aaaatgctct
    10501 ttaccatggc attaaggaaa aggaaggtca gggccatatt aaactttctg tccagaaaca
    10561 ggattcggga ttggtcatcc gtattgagga tgatggcgtt ggcttccaag atgctggtga
    10621 tagtagtcaa agtcaactca aacgtggggg agttggtctt caaaatgtcg atcaacggct
    10681 caaacttcat tttggagcca attaccagat gaagattgat tctagacccc aaaaagggac
    10741 gaaagttgaa atatatataa atagaataga aactagctaa ctcccagtca attctgggag
    10801 ttttatgcgt aattgggcaa attttctagg ttgtctatct tgctaaaaac aagaaaaaac
    10861 ggtatgatag aagagtgaca acagaggtaa cagagatgaa cgagacacag attcaaagag
    10921 aaacacgtca ggtagtggaa gatgttttag aaaagaccaa tttgaagcag ggggcccttt
    10981 ttgttttagg tctatcttct agtgaggtgc taggtggtca gattgggaaa gaatccagtc
    11041 aagagattgg tgagctgata gtggagacta tcttgggtat tctaggtagt agaggtatcc
    11101 atttagcagt tcaaggttgt gagcatgtca atcgggctct cgttgttgaa cgtcaggtgg
    11161 cagagcagtt tgatctggaa attgtcagtg tccatcctac tcttcatgca ggaggttcgg
    11221 ggcagttggc agcctttaag tttatgcagg atccagttga ggttgaattt atcaaggctc
    11281 atgctggatt ggatatcgga gacactgcaa ttggcatgca tgtcaagcat gttcaggttc
    11341 cgattcgccc tattttgaga gagattggtc atgcccatgt aacggcactg gctagtcgtc
    11401 caaaattaat cggaggtgcg cgtgcgcact atccgcaaga cgctattaga aagtcttgag
    11461 aatgaataaa ggagataaaa gtgtttaaaa aagaccgttt ttcaattcgt aagattaagg
    11521 gagttgtagg ctctgtattt cttggaagcc ttttgatggc tccttctgta gtggacgcag
    11581 ccacctatca ctatgtaaat aaagagatta tttcacaaga agctaaagat ttaattcaga
    11641 caggaaagcc tgacaggaat gaagttgtat atggtttggt gtatcaaaaa gatcagttgc
    11701 ctcaaacagg gacagaagca tctgttttga cagcttttgg tttgctgact gttgggagct
    11761 tgcttttaat ctacaagaga aagaaaattg ctagcgtctt tctagttgga gctatgggat
    11821 tggtagttct tcctagtgca ggggctgtag acccagttgc gaccctagca ctggctagtc
    11881 gagagggtgt tgttgaaatg gagggctatc gctatgttgg ttatctatca ggtgacatcc
    11941 tcaaaacgct tggcttggac actgttttag aagaaacctc agcaaaacct ggagaggtga
    12001 ctgtagtcga agttgagact cctcaatcaa caacaaatca ggagcaagct aggacagaaa
    12061 accaagtagt agagacagag gaagctccaa aagaagaagc acctaaaaca gaagaaagtc
    12121 caaaggaaga accaaaatcg gaggtaaaac ctactgacga cacccttcct aaagtagaag
    12181 aggggaaaga agattcagca gaaccagctc cagttgaaga agtaggtgga gaagttgagt
    12241 caaaaccaga ggaaaaagta gcagttaagc cagaaagtca accatcagac aaatcagctg
    12301 aggaatcaaa agttgaacca ccagtagaac aagcaaaagt cccagaacaa cccgtgcaac
    12361 ctacacaagc tgagcaacca agtacaccaa aagaatcatc acaagaagac aattctaaag
    12421 aagatagggg agcggaagag acaccgaaac aagaagatga acagccagca gaagccccag
    12481 aaatcaaggt tgaagaacca gtagaatcaa aagaggagac tgttaatcaa cctgttgaac
    12541 aaccaaaagt ggaaacgcct gctgtagaaa aacaaacgga accaacagag gaaccaaaag
    12601 ttgaagtaac aacagttgaa acaagagaag aagtcattcc ttttgaaaca aaagaacaag
    12661 aagatgacac tttaaaacgc ggaacaagac aagtagttca aaaaggtgta gaaggtaaga
    12721 aacaaattac tgaaacttat aaaacaattc gtggagaaaa aacaaatgaa gctccaatag
    12781 ttaaggaaac agtaattgaa caacctcaag atgagattat caaaaaaggt acaaaagggt
    12841 tagaaaaacc aacattacaa tgggctaata ctgaaaaaga tgtcttgaag aagagtgcta
    12901 cagctagtta tacattgact aaaccagctg gtgtagaaat taaatcaatt aaattagcgc
    12961 taaaagataa agatggacaa cttgttaaag aagtaacggt agctgaaaat aatttaaatg
    13021 ctactttaga taaattgaaa tattatcaag gttacaccct atctactaca atggtttatg
    13081 atcgtggaga aggtgaagaa actgagaaat tagaagataa acaaattcaa ttagacctta
    13141 aaaaagttga aatcaaaaac attaaagaaa caagcttaat gaatgttgat gctgagggta
    13201 acgaaactga taagagctta ttatctgaaa aaccgacaga tgtttcccaa ttgtatttac
    13261 gtgtgacaac tcatgacaac aaagtgacaa gacttgcggt aagttcagtt gaagaagttg
    13321 ttgttgatgg aaaaacattg tacaaagttg tagccaaagc tccagactta gttcaacgta
    13381 gagctgatga tacactgagt gaagaatatg ttcattattt tgaaaaacaa ttaccaaaag
    13441 taaataatgt atactacaac ttcaatgaac ttgtaaaaga tatgcaagct aatccaacgg
    13501 gtgagtttaa acttggtgca gacttgaatg cagcaaatgt aaaacctaac gggaaatctt
    13561 atgtaacgaa accatttaaa gggaaattac taagtaatga cggcggtaga tttacaatcc
    13621 ataatataga acgtccatta ttcgctaata ttgaaggtgg taaaatccac gatattaatc
    13681 ttgctaatgt aaatattaat atgccttggg ctgataaagt tgctcctatt gcaaatgtaa
    13741 tcaaaaataa tgcaaccatt gaaaatgtca aagttactgg taatgtcctg ggtaaagact
    13801 gggtatctgg atttatagac aaaattgacg gcagtggtaa attaattaat gttgcattta
    13861 tcggtaatgt tacatctgtt ggtactggag gcaacttctt aacaggtatt gtgggagaaa
    13921 actggaaagg atacgttgaa agagcatatg ttgatgctca tattaaaggt aagcgagcta
    13981 aagctgcggg tatagcctac tggtcacaaa accaagggaa taactttact attggatctg
    14041 agggggctat taaaaaatct gttgttaaag gtacaataga cgttgaaaaa ccaattgaag
    14101 ttggtggcgc tgttggaagt tttacttatc atggttctat tgaagatact gtttctatga
    14161 tgaaagttaa gaacggtgaa attttctatg gttctaaaga tattgatgat gatccatatt
    14221 acacaggtaa ccatgttaat cgaaactacg ttgttatagg tgttagcgaa ggtacttcta
    14281 catatagata ttctaatcag cataatcgta ttaaacctat aacacaatca gaagctgatg
    14341 ttaaaattgc agagacagct atcacagcag ataaatttac aattaccgat ccaattgtaa
    14401 ataaacttaa cgctctcaca acacgtgata atgagtatag aacaacacaa gattacgagg
    14461 cgactcgcga acaagcttat cgcaatattg aaaaacttca accgttctat aacaaagaat
    14521 ggattgtcaa ccaaggtaac aaacttgtag aaggttcaaa cttgttgaca aaagaagtat
    14581 tatctgttac aggtataaag agcggtcaat tcgtaactga tttgtcagat attgataaaa
    14641 ttatgattca ctattctgat ggagcaaagg aagaattgaa tgttactcgt caagaatcaa
    14701 acgttcaaca agtgcgtgag tacagtatta cagatttaga tatactctat acaccaaata
    14761 tggttgagaa agatcgcgct cagttgatga ctgatgtaaa gtctaagcta tctagtgtag
    14821 aattagagtc tgatggagtg cgtcaacttc tcgttaagag agatactaag aaagatgcga
    14881 atgcaaatag tgtaggtcgt caaaatggat acattagaga tttattcctt gaagaaagtt
    14941 tctctgaagt taaagcaaat cttgacaaat tggtaaaaca gatacttgaa aatgaagatc
    15001 atcaactcaa cgataacgaa ttagctgaac gtgctttact gaagaaagtt gaagataata
    15061 aagctaaaat catgatggga ctggcatact taaatcaata ttatgctttt aaatacgatg
    15121 agttatcaat taaagatatt atgatgttta aacctgattt ttatggtaag acagcaagtg
    15181 ttattgatag attgattaat attggttctg cagaaaataa tctaaaagga gatagaacgc
    15241 aagatgctta tcgtggtata atttcagggg caacaggtaa aggtagttta catgacttct
    15301 tgacctacaa tatgaaatta ttcacaaatg aaacagacat aaatgtttgg tttaaaaaag
    15361 ctattgaaaa gaatgcttat gtagttgaac aaccatcaac gaaccctgca tttgccaaca
    15421 aaaaatatcg tctatacgaa ggaattaata atgggcaaca tgggcgcatg attttacctc
    15481 ttcttaactt gaaaaatgca catctattta tgatttcaac atacaacact atctcgttta
    15541 gttcgtttga aaaatatggc aaagacacag atgaaaaacg tgaaaagttc aagagtgaga
    15601 tcaataaacg tgctaaagag caggttaatt acttagattt ttggtcacgt cttgctactg
    15661 ataatgtccg tgataaactt cttaagagtc aaaatgtagt tccaactcct gtatgggata
    15721 atcataatag cccgaacgga tgggctagta gacatggtca tatagatggg aaaccagatt
    15781 atgctccaat tcgtgagttc tttgggcgaa tcaataagta tcatggttac aaatatggat
    15841 atggcgcata tgcatatatt tttgcagcac ctcaaccgat ggatgcagtt tatttcgtta
    15901 tgacagattt aattagtgac tttggaacat ctgcatttac acatgaaact actcacgtta
    15961 atgatcgtat ggcttactat ggtggtcatt ggcatcgtga aggtacggat cttgaagcat
    16021 ttgctcaggg gatgttacaa acgccatcgg tatcaaatcc aaacggagaa tatggcgcat
    16081 taggtctaaa tatggcgtat gaacgtcaaa atgatggaaa tcaatggtat aacacaaatc
    16141 caaacgacct tacaactcgt gcagaaattg ataactacat gaaaggtttc aacgacacat
    16201 taatgcttct tgattacctt gaaggagaag ctgtcctcaa taaagcaaat caagatttaa
    16261 acaacgcttg gttcaaaaaa gtggataagc aacttcgtgg agctagtacg aagaaccagt
    16321 atgataaagt tcgtgattta acggcagatg agaaaaatat cactctaaat tcagtagatg
    16381 atttagttga taataatttt atgacgaaac acggacctgg aaacaatgta tatgatccaa
    16441 ctgggttcgg aacggcctac gtgactgtac ctattactgc aggtatttat ggaggtaaca
    16501 caagtgaagg tgctcctggt tctatgtcat tcaaacataa cacattcaga atgtgggggt
    16561 actacggata tgaaaaagga ttcttaaact atgcttctaa catgctgaaa aatgagtcta
    16621 gacaggctgg tcacaatact ctaggtgatg atttcatcat taagaaagtt tctgataata
    16681 aattcagtac attggaagat tggaagaaag catacttcaa agaagttgta gataaagcta
    16741 aagcaggatt taaccctgtt acaatcgaca gtactacata tagtagttac gatgacttga
    16801 agaacgcatt tgctgcagca gttgaaaaag ataaagctac tcttaaaaat ggatcagtta
    16861 aatctgacaa tactgttgca cttaaagaga aaatatacaa aaaacttctt caacaaacag
    16921 atagctttaa aacttcaatc tttaaataat tgaaatctct catctgcttt gcggatgagg
    16981 gttttcttat tttatgctat acttaaggta tgcatagaaa aacagtgatt gattttagga
    17041 ctttggggga gagatatacc tttacccagc ctattaaaga gttgaaaacg agaaatgtag
    17101 aagaagtggc agatttgctg gcacaagtgg aaagctacca agagcaaggt tattatgtgg
    17161 tggggtatgt cagctacgag gctgcacctg cttttgagga aaaattagca gttcacaagg
    17221 atcccctact gggagagtac ctgctttatt ttactgttca tgatagcgta gaaacttccc
    17281 ctattcctct gacttatgag gatattgatt tgccctcaaa ttggcaggaa gtaacgtctg
    17341 cagcagacta tgaaaaggcc attgcccaaa ttcaccatca tttacggcag ggagatacct
    17401 atcaggtcaa ctacaccgtc caacttaagc aaaagttaaa tgccaatcct tttgccatct
    17461 acaatcgtat ggtggtagag caggaggcgg gctacaatgc ctatgtggaa catgacgaga
    17521 tggcagtgat ttccatgagc ccagagctct tttttgagca aaatgatcgc gagttgacaa
    17581 cacgaccaat gaaggggacg actcagcgtg gggtaactga ccaagaagat cttgaacagg
    17641 ccagttggtt ggaacaggat cccaaaaatc gctctgaaaa tatgatgatt gtggacctct
    17701 tgcgcaatga tatgaaccgt atttctgaag ttgggagcga gcacgtggag cgtctgtgtc
    17761 aggtagagca gtattcaact gtttggcaga tgacttcgac catcaagagt cagttgcgag
    17821 aggatgtgga ccttgttgaa atcttccgct cactctttcc ttgtggttcc ataacgggtg
    17881 caccgaaaat tgcgacaatg gagattatca aggacttgga gcctcaaccg cgtggagtct
    17941 actgtggaac gattggtctc ttgcttccaa atggacgacg gatttttaat gtggccattc
    18001 gtaccattca acttcacaaa ggtcaagcca tttatggagt tggcggaggg attacttggg
    18061 atagcacatg ggaatctgaa taccgagagg ttcatcaaaa ggcagcagtt ctttatcgta
    18121 aacaagctcg cttccaactg attacgacag gggaaatcag ccagaagaac ctgctgtttg
    18181 aagatcaaca tctggaaaga ctgagaaaag ctagtcgtta ttttgctttt ccttttgatg
    18241 cagaaggctt gggacacaag attgaggaag agtgtcagga ttgtgaagct aatcgagatt
    18301 accgcttgcg aatcagcctt agcaaatctg gagagataga agtcaatcgc caagtattaa
    18361 cccctctcag tacaagcttt tgtcaggccc aagtctgtct tcaggaagct gctttgaatc
    18421 aatcctttac ctactttaaa accactcacc gaccgcattt gagcctagga gaacaagaga
    18481 agatttacca caataagtca ggagaactgc ttgaaacctc tataggaaat ttggttctga
    18541 aaatcgctgg aaaactctac acaccgccta tccgacttgg aatcttgcca ggaatttacc
    18601 gtcagcattt gctagaaaca ggacaggtag aagagaaagt cttgaccttg gcagatttaa
    18661 cccaagcaga agctatttac ggctgtaatg cagtgagagg cttgtatgaa ctaagccttg
    18721 aggagaacta gatgaaatta atatttttgc atgggttagg gcagtcagca gagtcttgga
    18781 aagaagttcg gaatctactg acagattatc cttctgaggc tatcgagtta tttccttctg
    18841 gagttagtaa ctatcaacaa gctaaagagc gagtttatca gcacctagct caagagacag
    18901 aaccttttgt tttgattgga ttgtccttag gtgctgccct gacactagaa ctttccagtt
    18961 acgatttacc aaatcttcga gctttgattc tgtcaggatg cccgcttaaa ttagcaggga
    19021 atatcctatt ttatcttcaa ttgctgattt ttaaactact tcccaaaaga gtatttgaaa
    19081 aacagggagc agacaagact cttatggtcg gagtttctga ggagttgaag acacttgatt
    19141 taacggatat agcaggaact tacccttatc caaccttact aatttgtggc agcaaagata
    19201 aaccgaatct tagttttatg aaagctctcc atagactgtt aacagattcg cagtttcaga
    19261 tcattcctga tggccctcat gtcttgaata aggcaaaacc aaaggagttt gtagaaaaga
    19321 ccagaagttt ccttgaattg ctgaaataag tttgataaaa taatattgaa atcgatatca
    19381 taattatggg agaaagaaat gaataaacgt ctatttttaa aaatgagtct ggtgacgttg
    19441 ccaattttag ccttgttttc acaaccagtt ttggcggaag aaaacatcca tttttcgagc
    19501 tgtaaggaag cttgggcgaa tggctattcg gatattcacg agggagaacc tggttattct
    19561 gccaagttag accgtgatca tgatggtgtg cttgcgaatt gaaaaatgct cctaagggtg
    19621 cttttaaagc aaaacagtca acggctattc aaatcaacac aagttcagca acaacaagtg
    19681 gttgggttaa gcaggacggc gcttggtact actttgatgg aaatggaaat ctagtgaaaa
    19741 atgcatggca gggaagctat tacctgaaag ctgatggtaa aatggcacag agtgaatgga
    19801 tttatgactc ttcttatcaa gcttggtatt atttgaaatc agatggttct tatgcaaaaa
    19861 atgcatggca aggagcttat taccttaaat caaacggtaa aatggcacaa ggtgagtggg
    19921 tttatgattc ttcttaccaa gcatggtatt acttgaaatc agatggttca tatgctcgca
    19981 atgcatggca aggaaactac tatttgaaat cagatggtaa aatggctaaa ggtgaatggg
    20041 tttatgatgc cacctatcaa gcttggtatt atttgacatc agatggttct tatgcttaca
    20101 gtacatggca aggaaattac tatctaaaat cggatggtaa aatggctgtc aatgaatggg
    20161 ttgatggtgg acgttattat gttggcgctg acggagtttg gaaggaaggt caagcaagta
    20221 cagtttcttc tagtaatgat agcaatagtg aatattctgc tgctttagga aaggcaaaaa
    20281 gttataattc gttattccac atgtcaaaaa aacgtatgta tagacaatta acttctgatt
    20341 ttgataaatt ttcaaatgat gcagctcaat atgccattga tcatttagat gattaacaga
    20401 tactggtagg cgaaaaaatt ccttataatt catttacgca aacctttgca taagtgaatg
    20461 gattttgata tactagtact gtaagcattt tcaattacta cacaatgaaa aaggagaata
    20521 tgatgagtca aaagattatt gggattgacc ttggtggaac ttctatcaaa tttgcaatct
    20581 taacaacagc aggagaaatc caaggaaaat ggtcaatcaa gaccaacatt ttggatgagg
    20641 gaagtcatat cgttgatgat atgattgagt ctattcaaca tcgtttggac ttgcttggat
    20701 tggcagcagc ggacttccaa ggcattggaa tgggatcacc aggtgtggtt gaccgtgaca
    20761 aagggactgt tatcggtgcc tacaacttga actggaaaac ccttcaacca atcaaacaaa
    20821 agattgaaaa agctttgggc attccatttt tcatcgataa tgatgccaac gtagcagctc
    20881 ttggtgagcg ctggatgggt gctggagata accaaccaga cgttgtcttt atgacactcg
    20941 gtactggtgt tggtggtggt attgtcgcag aaggcaaatt gcttcatggt gttgctggtg
    21001 cagcaggtga acttggtcat atcactgttg actttgacca accaatctca tgtacttgtg
    21061 gtaaaaaagg ctgccttgag acagttgctt cagcaacagg gattgtcaac ttgactcgtc
    21121 gctatgccga tgaatacgaa ggcgatgcag ccttgaaacg cttgattgat aacggagaag
    21181 aagtaactgc taagactgtc tttgatctcg caaaagaagg agacgacctt gctttgattg
    21241 tttaccgtaa cttctcacgt tacttgggaa tcgcttgtgc taacattggt tcaatcctaa
    21301 acccatcaac aatcgtcatc ggtggtggtg tgtcagctgc gggagaattc cttctacaag
    21361 gtgttcaaaa agtttacgat gaaaatagtt tcccacaagt acgcacatct actaaattag
    21421 ctcttgcaac tctaggaaat gacgctggag ttatcggagc agcatcactt gtattgcaat
    21481 aagataatga gagaggaaaa tgctaaccta gagttagtaa tgttcctctt ttatttttta
    21541 tgctatacta gttaggacaa tgaatgaggt gagagtaaat gacaaaagca gatacgattt
    21601 ttaaagagaa tattgaacgc attctaaagg aaggtgtttt ctcagagcag gctcgtccta
    21661 agtacaagga tgggactgtt gctaattcca agtatgtaac tggtgccttt tccgagtacg
    21721 acttatctaa aggagaattt cctatcacaa ccttgcgtcc cattgccatc aaatccgcca
    21781 tcaaagaagt tctctggatt taccaagacc agtcaaatag cttagaagtg cttaatgaca
    21841 agtacaatgt tcactactgg aatgactggg aagttggaga cacgggaacc attggtgagc
    21901 gctatggtgc cgttgttaag aaacacgaca ttatcaataa gcttctcaaa cagttggaaa
    21961 ccaatccttg gaaccgccgc aatattattt cgctctggga ttaccaagct ttcgaagaaa
    22021 cagatgggct gctcccgtgc gcctttcaga ccatgtttga tgtccgccgt atagatggag
    22081 aaatctatct ggatgcgacc ttgacccagc gctcgaatga tatgctggtg gcccaccaca
    22141 tcaacgctat gcagtatgtg gctttgcaga tgatgattgc caaacatttt ggctggaagg
    22201 ttgggaagtt cttctacttc atcaacaacc tccatatcta tgataatcaa tttgaacaag
    22261 ctcaggaatt gctccgtcgg gagccgtcaa actgccaacc acgcttggtt ttaaatgttc
    22321 ctgatgggac taatttcttt gatatcaaag cagaagattt tgagttggtg gattatgacc
    22381 ctgttaagcc acagttgaag tttgacctag ctatttaaaa gaatagaaaa aagaagttga
    22441 gaataatccc aacttctttt gtttcttaac gtgatacgcg gcgacgagct gcttttttac
    22501 ggttttcttc gatgaaagct gctttttgct cttctggttc gattactttc tttttaaatg
    22561 cgtatactgc acctgcaacg gcagcgacag ttcctgcgac acctgttaca agacctttag
    22621 cgaatccttt agccatgagt cttcctcctt tatattctca atcagccagc ctcctcaaga
    22681 ggtcacattt ttctgactga cctttttgtg ttataataat agtaacgaaa aaatgggaat
    22741 ttttcaagga aaaaagatga aaacaaaaat aattgtgatt gttggaccga ctgctgttgg
    22801 aaagacggct ctagctattg aagttgcaaa gcgttttaat ggcgaagtgg ttagtggaga
    22861 tagccagcaa gtctatcgag gacttgatat tgggacggcc aaggctagtc cagaagagca
    22921 ggcagctgtt cctcatcatt taatcgatgt tagagagata accgagtctt actcggcttt
    22981 tgattttgtt tcagaagcta agatgactat tgagggtatt cacaaccgtg gcaagctagc
    23041 cattatcgcc ggtgggactg gactttatat ccagagcttg ctagaaggtt accacctagg
    23101 tggggagact cctcatgagg agattttagc ttatcgagct agtttggagc catattcaga
    23161 tgaggaatta gcccatttgg tggatcaagc aggccttgag attccccagt ttaatcgtcg
    23221 tcgtgctatg cgtgccttag aaattgccca ttttggtcag gatttggaaa atcaagagac
    23281 cttgtatgaa ccgctgatta tctgcttgga tgatgaacgt agtcaacttt atgagcgtat
    23341 caaccaccga gtggatttga tgtttgaggc tgggcttttg gatgaggcca agtggctgtt
    23401 tgaccattcc cctaatgtac aggctgctaa aggaattggc tataaggaac tctttcctta
    23461 tttccgtgga gagcagacct tggaggaagc tagtgagagt ctcaaacagg cgacccgtcg
    23521 ttttgccaag cgtcagctga cctggttccg taatcgcatg caggtcacct tttatcagat
    23581 tggagaatct ggtgtacaag accgcatttt aagccagata gaggagtttt tagatgattg
    23641 aaacggagaa aaaagaggag cgagtcctgc tgattggtgt ggaattgcag ggtatggaca
    23701 gttttgacct ctccatggaa gaattggcta gtttagcgaa aacggcaggg gcagtcgttg
    23761 tagatagcta cagacaaaaa cgtgaaaaat atgattccaa gaccttcgtc ggctctggta
    23821 agttggaaga gattgcgctt atggtggatg cagaagaaat cactactgtc atcgtcaaca
    23881 accgtctgac cccaaggcag aatgtcaatc tagaggaagt tctcggtgtt aaggtcattg
    23941 accgtatgca gttgattttg gatatctttg ccatgcgggc tcgaagccat gaagggaagc
    24001 tccaagtcca cctagcccaa ctcaaatacc ttttgcctcg cttggttggt caggggatta
    24061 tgctcagccg tcaggcaggg ggaattggtt cccgtggtcc tggtgaaagc cagctggagc
    24121 tgaaccgtcg tagcgttcgc aatcaaatca cggatattga gcgccagctc aaggtggttg
    24181 agaaaaatcg ggcgactgtc agagaaaaac gtttggagtc tagcactttt aagattggtt
    24241 tgattggtta tactaatgct gggaaatcaa ctatcatgaa catcttgacc agtaagaccc
    24301 agtatgaagc agatgagctc tttgcgactc tggatgcgac aaccaagagt attcatctgg
    24361 gaggcaatct ccaagtaact ttgacagata ccgttggctt tatccaagat ttgccgacag
    24421 agttggtgtc cagtttcaag tcaaccttgg aagaaagcaa gcatgtggac cttctggttc
    24481 atgttatcga tgctagcaat ccttaccacg aggagcatga aaaaacggtt ctctccatca
    24541 tgaaagacct ggacatggaa gatattcctc acttgacgct ttataataaa gcggatttgg
    24601 tggaggattt cacgcctacc caaacgccat ataccctcat ttctgccaag tctgaggaca
    24661 gtcgtgaaaa cttgcaagca ttattgctag ataagattaa ggaaattttt gaagcattta
    24721 ccctgcgagt gcctttttca aagtcctaca agattcatga tttagagagt gttgcaattc
    24781 tggaagaacg tgattatcag gaagacggcg aagtgattac aggctacatt tccgagaaaa
    24841 ataaatggag gttagaagaa ttttatgact gatattaaaa ctttggctct aaagtatgga
    24901 ggttatacaa gtctggacaa ggtctatctg gatcagcttc tagctggtaa aacagagcag
    24961 gagcagttaa cacttattac acctccgcca agtgttgtta atgcctactt tgcagaactc
    25021 tatcagaaaa aaagtcctca ggctgcgacg gattattttg cagaactcag tcaggaactg
    25081 aatctttaca atactgagcc aagtttcacc ctagaaaata agccttttat tcggcttaat
    25141 ctgtctggta aatcctttgg tttttgttat gagagtgacg gctttggtcg gattttctct
    25201 gaaaatgagg agaaaatctc ggatgacttg ctctttgaaa ttgcgcaaat tttctcccat
    25261 caattagtct ttgaagagtc tggtaagatt tacatgaagc ctgtcaagga cgaggaagtt
    25321 gtcagcctag aaagtctcac agctttgact gatttggaaa gattggctga tggtcgaaaa
    25381 cgtctcaaag gctacagcca agaggattta ttgcaagaag ctgctgcttt ttctggcaaa
    25441 cgctatttcc gatcggaaaa ccgcacagcc atgttatata ttgattaatt agaaagtatc
    25501 gaatggatat tcaattttta ggaacggggg ctggtcagcc ctctaaagcc cgcaacgttt
    25561 caagtctcgc cctgaaactt ttggacgaga ttaacgaagt ttggctcttt gactgtggag
    25621 aaggtacgca aaatcgcatt ctggaaacca caattcgacc acgtaaggtc agcaaaatct
    25681 ttattactca tctgcatgga gaccacattt ttggtttgcc aggtttcctt tctagccgtg
    25741 cctttcaggc caatgaagag cagacagatt tggaaatcta cggacctcaa ggaatcaagt
    25801 catttgtctt aaccagcctt cgtgtgtcag gttctcgtct gccctaccgc attcatttcc
    25861 atgagtttga ccaagattct ctgggtaaaa ttcttgaaac cgataaattc actgtgtatg
    25921 cagaggagct ggaccacact attttctgtg ttggctatcg tgtcatgcaa aaggatctag
    25981 aagggacgct ggatgctgaa aaactcaagg ctgctggtgt tccgttcggc ccgctttttg
    26041 gtaaaatcaa aaacggccag gatcttgttt tggaagacgg aactgaaatc aaggcagcag
    26101 actatatctc agcgccacgt ccaggtaaga ttatcactat tttaggagac actcgaaaaa
    26161 cggatgccag tgtgcgtctg gctgtcaatg cagatgtcct agttcatgag tccacttatg
    26221 gcaagggtga tgaaaaaatt gctcgtaacc atggtcactc aactaatatg caagctgcac
    26281 aagtagcggt agaagcaggt gccaaacgcc tcctactcaa ccatatcagt gcccgtttcc
    26341 tctcaaaaga tataagcaaa ctcaagaagg acgctgccac aatttttgaa aatgtccatg
    26401 tggtcaaaga cttggaagaa gtggaaatct agcagtcaca gaaaggataa gtatgcctac
    26461 tattctcatt accggagcta gcggtggtct agctcaagaa atggtcaaac tcctgcccaa
    26521 tgaccaactc atcttgcttg gtagaaataa ggaaaaatta gcccaactct acggaaatta
    26581 ttcccatgca gaattgattg aaattgatat taccgacgat tcagccctag aagctctggt
    26641 aactgatctt tatctccgct atggcaagat tgatgtcttg attaacaacg ctggttacgg
    26701 gatttttgag ggatttgacc agattgctga taaagatatt caccagatgt ttgaggtcaa
    26761 tacctttgcc ctgatgaatc tgtctcgtca ccttgcggct cgtatgaagg aaagcagcaa
    26821 agggcatatc atcaacatcg tcagcatggc aggtctaata gctactggca agtctagtct
    26881 ttactcagcg accaagtttg cggctattgg tttttcaaat gctctgcgac tcgaacttat
    26941 gccctatgga gtctatgtga caacagtcaa tccaggacca atccgtacag gatttttcga
    27001 ccaagccgac ccagatggaa cttatcttaa atcggttgac cgcttcctgc tagaaccaga
    27061 tgcagtggct aaaaagattg tcaagattat aggaaaaaac aaacgagaac tcaatctccc
    27121 gattttgttg aacctagctc ataagtttta taccctcttt cctaagctag ctgataagtt
    27181 ggcaggggaa acttttaatt ataagtaaaa agaaccaatg tgcaggttgt tgctagccta
    27241 catattggtt cttatcattt ctcaactatc aaactgaact tcttctagga ggtagtctat
    27301 aaagcgttcg cccatcttag ataggctggt tttctcatgc tggatataga ccagctcaat
    27361 cgggtcatca atatccagtg ggatagaaac gatattgtct ccgtttaggt tgctgttcaa
    27421 aatccctgtc gcaatggtat aaccatccaa accaatcaag agattaaaga gggtggcacg
    27481 gtcactgacc acaatggatt tcttgtggtg ttcttgagaa agaatctctt ctgaaaagta
    27541 gaaggagttg tgcgtccctt ggtcatagct gaggtaaggg aaattctcca aatcagacag
    27601 tttcaccttg tctttctttg ccagagggtt ggtcttgctg acaaagatat gtggttgcgc
    27661 tgtgaagaga tggtgggcta gcaggtgatt gtcatccagc atcttggtta aaacatcacg
    27721 gttgtaactg tttaagaaga ggaccccgac ctcactgcgg aagttcttga cgtcgtcgat
    27781 aatctcccaa gtccgagttt cacgaaggaa gagttcgtat ttctccatat cgcttttctt
    27841 gagcaaagag acaaaggcat tgaccacaaa ggcatagtgt tgagacgaaa cgctaaatag
    27901 ttcgcggtgg gcgacaggat ttttatagcg ttcctccaga agctgggtct gctcgacaac
    27961 ctgacgggca taggagagaa actccatccc atcacgggtc aaggtgattc ccttgggatt
    28021 gcggataaag atctcaatgc ccatttcatt ttccaaatct cgcactgcat tggagagact
    28081 tggctgagtg ataaagagtt gcttggctgc ctcattcatg gagccagttt cgacgatttt
    28141 gataatataa tgtaattgtt gaattctcat gtttttattg taccatactt gccttagaat
    28201 cgctaaagaa gatgggaaaa taaggagcat tgtgtgagtc tcttcttgaa aaaaacacaa
    28261 aattttgcta gaatgagtct tatgaaaaca ttctatgatg tgcagcaatt cctcaaacga
    28321 tttggtatta ttgtttacat gggaaaacgc ttatatgata ttgaactgat gaagttggaa
    28381 ctatctcgga tttacgatgc agggttgatg gataaattag actatctaga ggcagaagca
    28441 gttcttcgca gagagcacaa ggtagaattg gattatattg agaaaaatgg agaaaagaac
    28501 taatggttac ttggattttg tgggcactta tactagcaat gttggcgtgg atgggcttta
    28561 actatcttcg tattcgccgt gcggctaaaa ttgtggacaa tgaggagttt gaagccttga
    28621 ttcgtacggg tcaattgatt gatttgcgcg acccagcaga attccacaga aaacatatcc
    28681 ttggtgcacg caatattcct tcaagtcagt tgaaaactag tcttgcagcc cttcgtaaag
    28741 ataaacctgt ccttctctac gaaaaccaac gtgcgcaacg agttacaaat gcagctcttt
    28801 acttgaaaaa acaaggtttt tctgagattt atatcctttc ttatggcttg gattcttgga
    28861 aagggaaagt gaagactagc taaccttatt tccaaattag ttgaatgata ggatgaagct
    28921 attgttttat agtataatta atttgtataa aatttaagga gttcttagaa catgaaagaa
    28981 aagaagaaaa tccacttttt gtgggtatct tgtcgattat tcttggtttg ttatttccaa
    29041 ttgtaggcct gattttgggt atcataggat tggtcttggc tatttcatac caaaaagagt
    29101 cacaattaga ctataaaata gaaaagattc ttaatatctt aggaattgtg atttctgtag
    29161 ttaactggat tgtagcaatc gccttaattt ttcggtaaat aaaagaaaaa agctttagtt
    29221 ttaaagcttt ttttatttta tcgactcatc tctaaatagt ttttaatgat ttgtaactct
    29281 ttttggttca aagggcggta gttaccttct gctaaatctg ggttcaatgt gaagtcccca
    29341 aattggattc tcttgaggct agtcacctta acaccaaccg agaggaacat tttcttgatt
    29401 tgatgaaatt ttccttctga aatggtgata gaggcttgac tgatggaggg acttgcagat
    29461 agaatctcta gttttgcggg tttacagaca gtaccatcta aaaagacaat tcccttttga
    29521 aaggcttgga tatggtcagg tgttagaagt ccattaacct caacttgata agtcttatcg
    29581 acatgatatt ggggatggag gagttggaag cccaagggac cgttatcggt caagagaagg
    29641 agtcctgttg tatctcggtc cagtcggccg acggcataga gcttgtcaga ctggatgtca
    29701 gatggaagca ggtccatgac ggtcggaagt tccttgtctt tgttggctgt aacgacacca
    29761 gcaggtttat gaagcataag ataggtgtgt tcatagcctt gaatgattcg atcctgaaaa
    29821 aggagttctt gtagtcctgt atcgatattt tgagctaggg agcgggctgg gcaaccatcg
    29881 actagaattt cccctctgag gagtgcttgt ttcatggcct ttcggctgat tttttcttga
    29941 gctaataaat tatctaaacg catactgtgc ctatcttatc ataagtcgct tgctttgaaa
    30001 aggcttgacg tgaaaagaaa agcggagtga aaacatttac acttgcttga gttatgttat
    30061 ttatttgaaa ttatggtata atcgttcagt tagaaaataa attttgaata ttatagagga
    30121 aatcatgaca aaattaagag aagatatccg taacattgcg attatcgccc acgttgacca
    30181 cggtaaaaca accctcgttg acgaattatt gaaacaatca gaaacgcttg atgcacgtac
    30241 tgaattggca gagcgtgcta tggactcaaa cgatatcgaa aaagagcgtg ggattaccat
    30301 ccttgctaaa aatactgccg ttgcttacaa cggaactcgt atcaacatta tggacacacc
    30361 aggacacgcg gactttggtg gagaagttga gcgtatcatg aaaatggttg acggtgttgt
    30421 cttggtcgta gatgcctatg aaggaaccat gccacaaact cgtttcgtat tgaaaaaagc
    30481 cttggaacaa gaccttgtcc caatcgtggt tgttaacaaa atcgataagc catcagctcg
    30541 tccagtagaa gtagtggatg aagtcttgga acttttcatc gagcttggtg cagatgacga
    30601 ccagcttgat ttcccagtgg tttatgcttc agcgatcaac ggaacttctt cattgtcaga
    30661 tgatccagct gaccaagaag cgactatggc accaatcttt gacacgatta tcgaccatat
    30721 cccagctcca gtagataact cagatgagcc tttgcagttc caagtgtcgc ttttggacta
    30781 caatgacttc gttggacgta tcggtatcgg tcgtgtcttc cgtggtacag ttaaggttgg
    30841 ggaccaagtt accctttcta aacttgacgg tacaactaaa aacttccgtg ttacaaaact
    30901 cttcggtttc tttggtttgg aacgtcgtga aatccaagaa gccaaagcgg gtgacttgat
    30961 tgccgtttca ggtatggaag acatctttgt cggtgaaacc atcactccga cagatgcagt
    31021 agaagctctt ccaatcctac acatcgatga gccaactctt caaatgactt tcttggtcaa
    31081 caactcacca tttgctggta aagaaggtaa atgggtaacc tctcgtaagg tggaagaacg
    31141 cttgcaggca gaattgcaaa cagacgtttc ccttcgtgtt gacccaactg attcaccaga
    31201 taaatggact gtttcaggac gtggagaatt gcacttgtca atccttatcg aaacaatgcg
    31261 tcgtgagggc tatgaacttc aagtatctcg tccagaagtt atcgtaaaag aaatcgacgg
    31321 tgttaaatgt gaaccatttg aacgtgtaca aatcgacact ccagaagaat accaagggtc
    31381 tgttatccaa agcctttctg aacgtaaagg tgaaatgttg gatatgattt caactggtaa
    31441 tggtcaaact cgtttggtct tccttgttcc agcgcgtggt ttgattggat actcaactga
    31501 gttcttgtca atgactcgtg gttacggtat catgaaccat accttcgacc aatacttgcc
    31561 attgattcca ggggaaattg gtggacgtca ccgtggtgcc cttgtttcta tcgatgctgg
    31621 taaggctaca acttactcaa tcatgtctat cgaagaacgt ggtacgatct ttgtcaaccc
    31681 aggtactgag gtttatgaag gaatgatcat cggtgaaaac tctcgtgaaa atgacttgac
    31741 agttaacatc acgaaggcaa aacaaatgac caacgttcgt tcagctacta aggaccaaac
    31801 agctgttatc aagacgcctc gtatcttgac acttgaagag tctcttgagt tcttgaacga
    31861 cgatgagtac atggaagtaa cgcctgagtc tatccgtttg cgtaaacaaa tccttaacaa
    31921 agcagagcgt gagaaagcta acaagaagaa aaaatcagct gaataagagc tagaaagaga
    31981 gaaagatggt ctatttagtc ctaggaattt tactgctcct actctatgta tttgcgacac
    32041 cagaaagcat taaagggact gtcaatatcg tcgctatggt atgtatttta gtggcactct
    32101 tgattttatt ggttctatct tttctgaaaa tttttcaatt accaacagaa atattcctag
    32161 caatagccat gttgatccta gcttacttta gtgttagaga catcacactc atgccagtca
    32221 aaaaaagtaa aagaagataa aaaagagagt ttcggctctc tttttgctag gaattttaca
    32281 atagtttgaa ttgcttttta gttaacacca tctcttttac ttgtatagta tgaatgggaa
    32341 aaacttgaat aaaattcgtt aatggcatct attttatatt tggttagtac tggttgcata
    32401 ttattttgaa ataaaactac tatataatat tattcataga gataatatag taaaacatct
    32461 aaaaaattcg attttttcct tgacaacaaa taataaaaat gttattctta tcacataaga
    32521 aagcgatttc aacaaaagag agaggaggat ttattttgtt gcattgttgc tcaaggtgtg
    32581 atttttttga aagaaaaaat aaaatgaaaa cgaaaaaaca tagattactt gctctagctc
    32641 ttatttcaaa ttttacatta ttgggagctg catcagctgc tgtacaatat ccagatggag
    32701 gagtatggac atatggagaa ggttcaggag gtggttaggc tttttcaaat tactatcatg
    32761 gtaaaaaata tcattattca tccatcgtga gcagatggga tggtcattct gataaaggag
    32821 aagctcctgc tggaaaaacc tcctatgcat ggatttggac taaatgggga gaacaagtag
    32881 cattttactg tgattatgac taatcgttca ttgatttaaa tcgttcccct tgtaagaaat
    32941 tacaggggga attttgttta caaggagtct actatgaaga aactattcat attattatca
    33001 actttttttc tcagcttctt ccttgcttgg attattgtct tacgtgcgcc acaatattta
    33061 tatgcaagct atgattccgt ttctttactt cgtgtcaaaa aagatactca ggaaccgacg
    33121 cgtgaggtat ttgaacagga attggagaat tttgcaaact cagaacagag tttaatagct
    33181 agaagaattg tagagccgag taaggatggg acgactcact ttacttatgc aacttatggt
    33241 cagggaactt taccaaaaga attccaagaa gctagccaag aaagtcgtga acgtagtgat
    33301 ccgctaaata gttatctcct tttgtcaggc tccttgacga aagaaaagct tgccgataaa
    33361 ttaggagatt tgggttataa agcaagtgct gaccgaaaga taccgcccta ttttcttgct
    33421 tttcgaatat tactaaatcc ccttatttta attagtttag caatatttgg tttatctttc
    33481 tttgctttag tgattatcac tcggattaag gaaatgagag cagcaggtat aaaactcttt
    33541 tctggtcaga ctctcttatc catcatgggg cattctttat ctactgatat caaatggctc
    33601 cttctatcag ccctcctttc cttcctaggt gggggagtcg ttctttttag tcaaggtttg
    33661 ttttatccta tcttgttagc cacctatggt tttgggatta gtttctatct gttgttttta
    33721 ttggcgattt caattttact aatgcttctt tatctaatga gtttgaatta caaagcatta
    33781 gttcccgtta ttaaggggag attacccctt aaacgcctga tgattttaac cctattgtgt
    33841 cagttggttg ctgtctttac agtaggatac gctgttaaga caggtttgac gtcttaccaa
    33901 cgattgaaag aacttgaaat ttcaaaacaa gcatggcagg atagagcaga ctattatcaa
    33961 atttcttttg gcttaggtga tagaggaaaa gatacagaaa atcagagcaa gtggtatgcc
    34021 tttgccaagg aagcaatcga agaagaacaa gctctttatg taaaggataa tctgctccat
    34081 tttgccaatc cacaaggaaa aaatgaacag ggagagacac tggataccta tagtccagat
    34141 gctaatacgc tctatgttag tccaagttat ttagacaagg aaaatgtggc tgtaaatgat
    34201 gagactagac agaaactagc tcatcttcaa aaaggggaat ttggactctt attaccagaa
    34261 tctcttcgtt cacaggaagc agaacttaag aaagtttttg aagaacgttt gaactattac
    34321 ggaaaatcaa gcgaggataa agacgctcct ttagagtatg aaatgagagc gattgttagc
    34381 tatcttccaa caggataaaa acgctttgtt tataataacg gtgaaagtcc agtatctatt
    34441 cagtacttaa ccgatccgat tttagttgta tttactccaa catctacagg tgatagtttc
    34501 atttcaaaat atgtttggtc tatcaatgct ggaaaacaac tctttatcaa aggatatgag
    34561 agtgggctag aactcttaaa gaaagctgga atttatgagc aagtatccta tcttaaagaa
    34621 ggaagaagtg tttatctaac tcgttataat gaagttcaaa ctgaaacagc aactttaatc
    34681 ttaggagcta ttgttgggat agccagttcc ttattactct tttattctgt caatcttcta
    34741 tatttcgagc aattccgccg agatatcttg attaaacgaa tttcaggttt acgatttttt
    34801 gaaacacatg ctcagtatat ggttagccaa tttgccagtt ttgtatttgg tgctagtttc
    34861 tttattttaa gcagtcgaga cttggtgatt ggcttgctca ctttattcgt ctttctagct
    34921 agtgcagttt tgacgcttta ccgtcaagca cagaaagaat ctcgtgtttc tatgacaatt
    34981 atgaaaggaa aataggatga ttgaactaaa gaatatatct aaaaaatttg gaagccgtca
    35041 gctattttca gatacaaatc ttcattttga aggtgggaaa atttatgcct taatcggtac
    35101 aagtggctgt ggtaagacaa cactcttgaa tatgattgga cgattagagc catatgacaa
    35161 agggcaaatc atctatgatg gcacttctct taaggacatc aagtcttctg ttttctttag
    35221 agattacttg ggatacttat ttcaagattt tggcttaatt gaaagccaaa ccgtcaaaga
    35281 gaatctcaat ctgggtttag ttggtaaaaa gttgaaggaa aaagagaaaa tctctttgat
    35341 gaaacaagct ctaaaccgtg taaacctctc ttatttggat ttgaagcaac ctatatttga
    35401 gttatcagga ggagaagcac aacgtgttgc attagcgaag ataattttaa aggatccgcc
    35461 tttgattctt gcagatgaac caaccgcttc cttagacccc aaaaactctg aggaattact
    35521 ttccatccta gaatctttaa aaaatccgaa tcggaccatt attattgcga cccacaatcc
    35581 tctgatttgg gagcaagtgg atcaggtcat tcgagttacc gatttatcac atagatgata
    35641 tggtaagatt cagttagaag aaagagtcac aaacacactt tgtggctttt ttatttccat
    35701 aaaaatggta aaatagtagg agtagaaatg gagttcgaga catgaaagta atagatcaat
    35761 ttaaaaataa gaaagttctt gttttaggtt tggccaagtc tggtgaatct gcggctcgtt
    35821 tgttggacaa gttaggtgcc attgtgacag taaatgatgg gaaaccattc gaggacaatc
    35881 cagctgccca atgtttgctg gaagaaggga tcaaggtcat tacaggtggc catcctttgg
    35941 aactcttgga tgaagagttt gccctcatgg taaaaaatcc aggtatcccc tacagcaatc
    36001 ccatgattga aaaggctttg gccaagggaa ttccagtctt gactgaggtg gaattggctt
    36061 atttgatttc agaagcaccg attattggta tcacaggatc gaacggtaag acaaccacaa
    36121 cgactatgat tggggaagtt ttgactgctg ctgggcaaca tggtctttta tcagggaata
    36181 tcggctatcc tgccagtcag gttgctcaaa tagcgacaga caagaacacg cttgttatgg
    36241 aactttcttc tttccaactc atgggtgttc aagaattcca tcctgagatt gcggttatta
    36301 ccaaccttat gccaactcat atcgattatc atggattatt tgaggaatat gtagcagcca
    36361 agtggaatat ccagaacaag atggcagcag ctgatttcct tgtcttgaac tttaatcaag
    36421 acttggcaaa agacttggct tccaagacag aagccactgt tgtaccattt tcaacacttg
    36481 aaaaggttga tggagcttat ctggaagatg gtcaactcta cttccgtggt gaagtagtca
    36541 tggcagcgaa tgaaatcggt gttccaggta gccacaatgt ggaaaatgcc cttgcgacta
    36601 ttgctgtagc caagcttcgt ggtgtggaca atcaaaccat caaggaaact ctttcagcct
    36661 tcggtggtgt caaacaccgt ctccagtttg tggatgacat caagggtgtt aaattctata
    36721 acgacagtaa atcaactaat atcttggcta ctcaaaaagc cttgtcagga tttgacaaca
    36781 gcaaggtcgt cttgattgca ggtggtttgg accgtggcaa tgagtttgac gaattggtgc
    36841 cagatattac tggactcaag aagatggtca tcctgggtca atctgcagaa cgtgtcaaac
    36901 gggcagcaga caaggctggt gtcgcttatg tggaggcgac agatattgca gatgcgaccc
    36961 gcaaggccta tgagcttgcg actcaaggag atgtggttct tcttagtcct gccaatgcca
    37021 gctgggatat gtatgctaac tttgaagtac gtggcgacct ctttatcgac acagtagcgg
    37081 agttaaaaga ataaaatatg aaaaaaattg tctttacagg tggggggacg gttggacacg
    37141 ttaccctcaa tcttttgtta atgcccaagt tcatcgaaga tggttgggaa gtccactata
    37201 tcggggacaa gcgtggtatc gaacaccaag aaatccttaa gtcaggtttg gatgtcactt
    37261 tccactccat tgcgactgga aaattgcgtc gctatttctc ttggcaaaat atgctggacg
    37321 tcttcaaagt tggctgggga atcgtccaat cgctctttat catgttgcga cttcgtccac
    37381 agaccctttt ttcaaagggg ggctttgtct cagtaccgcc tgttatcgct gcgcgtgtgt
    37441 caggagtgcc tgtctttatt cacgaatctg acctgtctat gggcttggcc aataaaatcg
    37501 cctataaatt tgcgactaag atgtattcaa cctttgagca agcttcgagt ttgtctaagg
    37561 ttgagcatgt gggagcagtg accaaggttt cagatcaaaa aaatccagaa ccagatgaat
    37621 tggtggatat tcaaagccac tttaatcata aattgccgac tgtattgttt gttggcggtt
    37681 ctgcaggtgc tcgtgtcttt aaccaattgg tgacagacca taagaaagaa ctaacagagc
    37741 gctacaatat tatcaatcta actggagatt ctagcctgaa tgagttgagc caaaatcttt
    37801 ttcgtgttga ctatgtgacc gatctctatc aacccttgat ggaattggct gatattgttg
    37861 tgacacgagg tggtgccaat acgatttttg agctcttggc gatagcaaaa ttgcatgtca
    37921 ttgtgccgct tggtcgtgaa gctagtcgtg gtgaccagct tgaaaatgca gcttactttg
    37981 taaaaaaagg ctatgcagaa gaccttcaag aaagcgattt gaccttggat agtttggaag
    38041 agaagctttc tcacttacta agtcacaagg aagattacca agctaagatg aaggcttcta
    38101 aggaattgaa atctctagca gatttttatc aattgttgaa aaaagattta tcataaggaa
    38161 agtaaatgtc aaaagataag aaaaatgagg acaaagaaat cctcgaagaa ttgaaagagt
    38221 tatcagaatg gcagaaacga aaccaagaat atctaaaaaa gaaggctgaa gaagaggcgg
    38281 ctctagctga ggagaaggaa aaggaaagac aagctcgaat gggagaagaa tctgagaagt
    38341 cagaggacaa acaggaccag gagagtgaaa cagaccagga agattcagaa tcagctaagg
    38401 aagagtctga agaaaaagta gcatcctcag aggctgacaa agagaaagaa gagaaagaag
    38461 aatcagagtc taaagagaag gaggaacagg ataaaaagct ttctaaaaag gctacaaagg
    38521 aaaaaccagc caaagcaaag attcctggta tccatatctt gcgagccttc acgattttat
    38581 ttccaagtct gcttttattg attgtctctg cctacttgct cagtccttat gcgaccatga
    38641 aagatattcg tgttgaggga acggtgcaaa ctacagctga tgatattcga caggcttcag
    38701 gcattcagga ttcggattat acgattaacc ttctgctaga caaggcaaaa tatgaaaagc
    38761 agattaagtc taactattgg gttgaatcag ctcaacttgt ctatcaattt ccaactaagt
    38821 tcactattaa ggtcaaggaa tatgatattg tggcctacta tatttctggt gaaaatcatt
    38881 atcctattct ttccagtggt cagcttgaga ctagttctgt gagtctgaac agtttaccag
    38941 aaacttattt atcagttctc tttaatgata gtgaacaaat caaggttttt gtctcagaac
    39001 ttgctcaaat tagcccagaa ctcaaggcgg ctatccaaaa ggtggaatta gccccaagca
    39061 aggtgacatc cgatttaatt cgattgacca tgaatgattc ggacgaagtc ttggttcctc
    39121 tatctgaaat gagtaagaaa ctgccatatt atagtaagat taagccacaa ttgtcagaac
    39181 cgagtgtggt cgacatggaa gctggaattt acagttacac tgtggcggat aaattaatta
    39241 tggaggctga ggaaaaagcc aaacaagagg ccaaggaagc cgagaaaaaa caggaagaag
    39301 aacagaaacg tttagaagaa gaacagaaaa aacaagagga agagagcaat cgaaatcaaa
    39361 caaatcagcg ttcatcgcgt cgctaggttt accttttctc ttatagttct ttagtgacca
    39421 tgtttttact tgacaagtgc tagtagaaat aatagaataa tagaaaacct ttaaagcagt
    39481 ccagagaggc agctaaggtt agacggtgaa agggtggaga ctacccattt ttcgtggaac
    39541 cttgctgttg gcaggttcct tttttcgtgg cttctgttgg ccagactctc tcactagtaa
    39601 aggtaaaagg agaaacctat gcgagaacat cgtccaatca ttgctcttga ttttcctagt
    39661 tttgaggcgg tcaaggaatt tttagctctt ttcccagcag aagaaagcct ttatctcaag
    39721 gtagggatgg agctttatta cgcagcgggg cctgagattg tgtcctactt aaaaggtttg
    39781 ggtcatagtg tctttttgga tctcaaactt catgacattc ctaatacagt caagtcagtc
    39841 atgaagatcc tatctcagct tggtgtggat atgaccaatg ttcatgcggc tggtggtgta
    39901 gagatgatga aggctgcgcg tgaaggtctt ggaagtcaag ctaaattgat cgctgtaact
    39961 cagctcacat caacgtcaga agctcagatg caggagtttc aaaatatcca aaccagtctg
    40021 caagagtctg tgattcacta tgccaagaag acagctgaag ctggcttgga tggtgttgtt
    40081 tgctcggctc aggaagtaca agtcatcaag caggctacca atccagattt tatctgtctg
    40141 acaccaggga ttcgtccagc tggtgttgca gttggagatc aaaaacgagt catgacacct
    40201 gctgatgcct atcaaatcgg cagtgactat atcgtagtgg gacgtcccat tacccaagct
    40261 gaggatcctg ttgcagctta tcatgccatc aaggatgaat ggacacagga ctggaattaa
    40321 agaactagat tagaaaaata aaaggagaat accatgacac ttgctaaaga tatcgctagc
    40381 cacctcttga aaatccaagc cgtttacctc aaaccagagg aacccttcac ttgggcatct
    40441 ggtatcaagt caccgattta cactgataat cgtgtgacac tagcctatcc agaaactcgt
    40501 accctaattg aaaatggttt tgtggaagct atcaaagaag cctttcctga agtagaagtg
    40561 attgcaggaa ctgcaacagc agggattcca cacggagcca ttattgctga taagatggac
    40621 ttgccttttg cctacatccg tagcaaacca aaagaccacg gagctggtaa tcaaatcgaa
    40681 ggtcgcgtag ctcaaggtca aaaaatggta gtggttgaag accttatttc aacgggtggt
    40741 tcagttcttg aagctgtagc agcagccaag cgagaaggag cagatgtact tggagttgta
    40801 gcgattttca gctaccaatt gccaaaagca gataagaact ttgcagatgc tggtgttaaa
    40861 cttgtgacgc tttcaaacta tagcgagctt atccatctag cccaagaaga aggttacatc
    40921 acgccagagg gccttgatct tctaaaacgc tttaaagaag accaagaaaa ttggcaagaa
    40981 ggttaggtca gtaagataaa gagagacgag gctaccgagt ctcttttacc attttattta
    41041 aaatatgaca atattttaaa taaaataatt gacaacgctt tcttttattg atataatgaa
    41101 aatgtaatat gtatcaaatt gatcaatcaa ctatcttgtt tatcacttct taagaggacg
    41161 atgtcatgaa aagaagaaaa atatattcct tttttgcgta gttacaattg catctagttt
    41221 gtttctccct acagttttag ctagacagat tggaaattat gatttaacgt tgccgcgttg
    41281 gggttcggat acaactagtg agcttgagaa agaaaacgcc tctgctggaa ttgataatag
    41341 tgacagcact ggtggcggta aaaggttaaa tacctctatt cgtagcgcct atagtgggtc
    41401 agatattacc ccggtatatt cattggggtc tggctctagg attgtcatgt actataatgg
    41461 aggtggtgac aattatattg gttctggtac tagattagct atggcgccac aatttggaaa
    41521 tcatgtaaga attcatactt caggttcttg gagtccagat tcttattaac ttacttgtca
    41581 gagtaagcct taaagatggt tgattgtggg tgtagcatga aaaaagaatg ctacacccta
    41641 tttttattat aaggaggagt aaggatggaa tttttcattt gtaatcttgt acgagtcgtt
    41701 caatcacctc gattttatat gtctttattt ttgacccttc tttgcatgag tttaggaaat
    41761 ttccttgctt tcaatggtat ttataaaatt gaaggtttat cgattttttt tgccgcttct
    41821 tctattcgag gattttcacc gattagccta gtagctgcac ttatctgtac actgccctat
    41881 tctagtcaga taatagagga tgctgagagt cattttctaa cagcacaatt gtgccgaatt
    41941 tctaaaaaga ggtatctagc tattgtaggt agtactgcaa ttatttcttc ttttctagtc
    42001 ttttttctcc cctatttatt attattagga attaatcttt tagtgactcc ttatcaggaa
    42061 atttatattg gagattatag tggtgcctta aaagaattat ttgattctaa tcagttgctc
    42121 tatagtcttg tgacgactct ctggtatgga gtttggggcg ctgtgttctc tatttttgga
    42181 ctagctagtg ctttgctagt gaagaaaaaa ataggagcta ttttcatccc agttgcctat
    42241 atgatggttg gtggtatttt ttgggctatt ttagggctat cttacttaga acctgtgaca
    42301 acattagctt tgggatatca gaaagatatc agtctttcct tagttagtgg gcatcttgct
    42361 tttattttat ttgttagttg tttggttgtt tatggtacat tttttctaca ttcagaggac
    42421 tatgtataat gaaacaattt gttcaatttt ataaaaaaga tttcttagca gtattggttt
    42481 attttatatt actgctatcc tgtgttttat ctagtacagt atatttattg cgctgtcgcc
    42541 aatattcaat ccatccaaat gtattagaat ggatcttagt tttacttcaa gatatgacga
    42601 ctggagtata ttgctttccg ttcacatata tattgttctt tttttatttg atgaataact
    42661 attttaatag gttggagtgt cgcattcgtc tgaaatcaat taagcacttt accagtttta
    42721 gtttcaaatt agcagctctt agtacgggga tttggacggc gattttattt ttattgattt
    42781 ttctaattgc atttagtaat ggttttagct tctctttgga gataaaggag gttgattttt
    42841 taagagaatt ttatggcata agtattgcaa acaatgctag tttctttata ggattttttt
    42901 tctcttatat agcatactat ttctttttat ccttacttac tattagcagt ttttcttggt
    42961 ttaaaaaatc aaacatgagc ttagtatttc tgtttacttt tttatttgta gaatccttat
    43021 tctggattta tcagttgaac aatgggataa ttggattatt gccaattttt cagtatatgg
    43081 taaattccaa tccgtatgca ttgatttatt ggcttgcatt actatctatc ataattccat
    43141 tgactgtatt ttctgttcat agaaactgga ggagagtgta aaagttggaa atgggaaagt
    43201 taagtagtca catgtggagg ttgaatcaga taatctatac caagtacttt tggggttatg
    43261 ttcttttttg gatattgatt tgtttaggat tatggtattg gttagaagga aatgatagac
    43321 ttgttataga aattttaaaa gggcctaatc tgagtcaaaa ctctttttta gtcttatcta
    43381 tatggttgct tcattggttt attattcata cattttttct agcaattgta tatcgtagaa
    43441 gagcatccga tttctttatg gaagtgattc gattttcttc tattaagctc tggattaggt
    43501 atcagatttg gacctgtttt ctttatggac tcattttaat catggtaaaa gttctagtga
    43561 ttcaatttat gttacagtta ccaaactggg atataggagt tttgtttata gttgattctt
    43621 tgaatgcttg tgtgttagtc ttgttttgct ttatgttata cgcactagga gcgaatgtac
    43681 aaatgaactt tgcttgcgtt agtttctttt tactcatgat tgtgtttggt ggtctatttg
    43741 taggaaatcg aactaattat ctattttata ttttgaatcg agggaatgga gatataggac
    43801 gagatttatt tcttcagttg ctatttttag tctttctttt taaaagcatt ttctatttca
    43861 ctcgtcaaaa gaggaggttt atagaatgaa tgaaataatt acattaaaaa atattgagtt
    43921 gaaattaaaa aaaacatgtg tttttcaaaa ccttaatttt agttgtaaac agggggaaat
    43981 tataggaatt actggtgcga atggctcagg gaaaagtgta ttgtttaaat taatagctgg
    44041 tttatatagt ccgtcttatg gagaagtgtt aatcaatggg gaaaatattg ttcctgagag
    44101 aaaaattcca gctaatttgg gagctttgat tgaagaacct ggttttataa attattatag
    44161 tggctttaag aatttacaat atttggcaag catacgagga gtagttggta atcaggaaat
    44221 caatgataca ctgaaaatag ttggtctata tgagcaaaaa gaccagaaag ttaaaactta
    44281 ttcgctaggt atgaggaaaa agctagggat tgctcaagca attatggaga atccctctat
    44341 tcttttacta gatgaaccta tgaatgcctt ggataaatca agtgtagaaa atatgagaac
    44401 attgtttaga gagctctcta gtgaaaaagg gacaacaatt ttgattgcta gtcatagtga
    44461 agaggatatt cgtatcttat gtgataaagt atatgcaata gaagataaag tatgtacatt
    44521 gtgttcagat tgaacatctt agatagactc aggatgttat aggtaaaatc ttaaaaaggg
    44581 attggagctt aaaatccagt tccttttaag agttaatgac taatcaactt ttccaccttc
    44641 aacaaccagg tcatctgctt tagcagcgtc accgtaggtt gggtgaagtg ttttttcata
    44701 ggccttgtgg aagaagtttt ccttgcctaa tttttcaata tctttattga tgaagtctag
    44761 caattcttgg ttgccttttt gaactgctgc cgcaatggta tcgggatcac cgagggaagt
    44821 aattcctact tcaaatcctt tattttcaag cgcccaagct agaacttccg tattatcagt
    44881 tgaaaaggca tctccacgtc cgtcaagaag aacttggtaa gagtcactgt attggtcgta
    44941 tttttggagt ttgatttctg gatgattctt ttcaaaataa gtctcagcag tcgttccttt
    45001 tgtgacaatt aaggttttac cttcaagttg tttgacgtct gtaatgagac cagtcttagg
    45061 tgatacgaca cccagagaaa ctttcatata tggaagggca aaatcaactt gtttcttacg
    45121 ttcgtcagtt actgtaaagt tagcaagaat aatatctacc ttgtttgaaa tcaagtattc
    45181 cgcacggttg gcggcatcga ctgaaatgta tttaaccttg acaccaaggt cttgagctag
    45241 ttggttccct agttcaatat cgtagcgtag ccttggtaag aaccatcatt gtcaacgtag
    45301 ccaaacggtt ttttatctcc aaacacggcg attcgcagtt caccgctttt tttgatttca
    45361 tcgatagtgc gagctttggc agttgttttt ccagaggatg aaccagcgtt tccacctgag
    45421 ctacaagcag tgataaagat aagggcaaag gcaagtacta aaacagttaa gagtggtttg
    45481 aatagtttca taagaatctc ctttatagat atgagccgaa ttggctaaag tcaaagacgt
    45541 ttaaaaattc ctgggctcgt ttggtttgcg gattggtaaa gaaggcttga gctgttcctt
    45601 cttcagcgat tttcccttgg tcgaggaaga taatccggtc agcaatggct tgggcaaact
    45661 gcatttcgtg ggttactaaa atcatggtac ggccttcttg ggccaaatca ttgataagtt
    45721 ccagcacctc acgcaccatt tctggatcca gcgaagcagt cacctcgtca aaaaggatga
    45781 tttctggatg cattaggagg gcacggacaa ttgcaacacg ttgcttctgt ccaccagata
    45841 attgacgggc aaagctatgt tgtttatcca gcaaaccgac acgctctagt aattgcaaag
    45901 cttcttccgt tacttctttc ttgtcccttc cttgagcttt gatagggcct aggatgaggt
    45961 tttgtaagac atccagatgg ggaaagagtt cataactttg aaagaccatg ccaatctttt
    46021 ggcgaactag gtgaaaatct tttttatttt caacgataga ctgaccatcc agaagaatat
    46081 ctccaccttg aatactttct aagccgttga ggcaacgaag gagggtactt ttcccacaac
    46141 cagatggccc taggatgaca acaacttccc cttttttgat ttctagagaa agtccttgga
    46201 ggatgggatt gtctccgaag gattttttta gttccttgat ttctaagata gtttcagaca
    46261 tttagtttct ccaatgtttt tctaagtgag tggatagttt ggaaataggg tagcaaactg
    46321 cgaaatataa gattagaatg gttccataaa ttcaaaatga agcagttggg atggtcaggc
    46381 gattgctatc gatgatttgt tgtccaactt tggtcacttc cacaacccca atcaaaacaa
    46441 ctaatgaagt ggttttaatc atccgagtga caagattgat agcctgcggt agcagtcttc
    46501 ttaagacttg tgggatgatg atgtggtagt aaagttgaac attagtcaag ccgagtgcct
    46561 gtccactttc aaactgatgt ttagggagag aagtgatagc tccacgtacc aagtctccca
    46621 tttcagctgt tccccagagg gtaaaaacga taatagctga agtctcacct gagatattga
    46681 tattaaagtt tcgagccaag ccaaagtaaa cgatgaagag tagcaccagc tggggcatga
    46741 tacggataaa ttccagatac aatcgtgtta aaaatcgtat gattctagaa tgggaggtca
    46801 tgatgattcc catgactgtt ctgaacatca tggataagag gacagacagg atggatatcc
    46861 caatcgtaac gcccaatccc tgtaagattc tcaggagatt atttccttga aagagtactt
    46921 ggattcccga atcctgcatg gcggagcctc ctttctatcc agctaaagac cagtgagatg
    46981 ggtagcagca tgatcagata agcaactacc aacatagcta gcgcaatgtc tgtctcatag
    47041 tagagaccaa tcaaatcctt ggcgacgtac atgaggtcgg ccaaagccac tgctgagaaa
    47101 acagaggttt ccttgataag gaaaatgaca ttggcactaa aggaggggag tgccaccgct
    47161 gttgcttgcg gaagaaccac atagtaaaag acctgtagag gtgtcagacc aatagcgagg
    47221 ccaatctcct gctgggtttg actgatggct tccagcccac ttcggaaaga ttctgccata
    47281 taggagcctc ctaaaaagac aagcccaagc gttgcacaga cttctgaaga taggacaatc
    47341 ccgattcggg gaagaccgaa gtagagaaag aagagttgaa tcaaaagggg cgtattacgt
    47401 gacaattcaa tgtaggctgt cgctacttgc gccaaaataa ggattcgata atgtcggatg
    47461 atactaacga ttaaaccgag cagaaaggat cccaaaattc cccaaactgc aatatgcaag
    47521 gtcagaaaga atgccttttg atatagtggt agatattgtt caacaatgga tcaatccaaa
    47581 aatagaacct cccatctaga aataatacag ttattgtagc acttaaaatc ttctttggat
    47641 aatatctatt ttttattgcc gttataagga tttttatcat agacataaaa tttctgaaat
    47701 ttccaaacaa aatattttaa aagttttgaa aaagagttaa gatatttttg taatacacaa
    47761 agtaaacgct tacttattaa ggaggacatt ttatgtcata caaaacaagc aatgcagaag
    47821 gtcatgtaga tttcatcaat acctatgatt tggagccaat ggcgcaacaa gttattccta
    47881 aagcagcatt tggctatatc gctagtgggg cgggagatac tttcacttct ttccagtgat
    47941 tttagcgtca ggttcttttt agtttttaaa gattatccgt gaatttcttg cttatttatg
    48001 ataaaatggg agtatcgcaa aaaatgactc atcgtattca attttgagta aaactaggag
    48061 gatcccatgt ctacagaaca tatggaagaa ctaaatgacc agcagatcgt tcgccgtgaa
    48121 aaaatggctg cgctccgcga acaaggaatc gatcctttcg gaaaacgttt tgaacgtact
    48181 gcaaattcac aagaattaaa agataaatat gccaacctcg ataaagaaca attacacgat
    48241 aaaaacgaaa cagctactat cgcaggacgc ttgataacca aacgtggtaa aggaaaagtt
    48301 ggttttgccc accttcaaga ccgcgaaggc cagattcaga tctacgttcg taaggatgct
    48361 gtcggtgaag aaaactacga aatcttcaaa aaagcagacc ttggtgactt ccttggtgtc
    48421 gaaggtgaag tgatgcgtac ggatatggga gaactctcta tcaaggcaac ccacatcaca
    48481 cacttgtcta aggctcttcg tcctcttcct gagaaattcc atggtttgac agacgttgaa
    48541 acaatttacc gtaaacgtta ccttgacttg atttctaatc gtgaaagctt tgaacgcttt
    48601 gtcactcgtt caaaaatcat ctctgaaatc cgtcgttacc ttgaccaaaa aggattcctt
    48661 gaagtggaaa cacctgttct tcataatgaa gccggtggtg ctgctgcccg tccatttatc
    48721 acccaccaca atgcccaaaa cattgacatg gtgcttcgta tcgcgactga gcttcacttg
    48781 aaacgcctta tcgtgggtgg tatggaacgt gtctatgaaa ttggccgtat cttccgtaac
    48841 gaaggaatgg acgctactca taaccctgag ttcacttcta tcgaagttta ccaagcttat
    48901 gcagacttcc aagacatcat ggacttgacg gaaggcatta tccaacacgc tgctaaatca
    48961 gtcaaaggtg atggcccagt caactaccaa ggtactgaaa tcaagattaa cgaaccattt
    49021 aagcgtgttc atatggtgga tgctatcaga gaaattactg gtgtcgattt ctggcaagac
    49081 atgactttgg aagaagctaa aactatcgct gctgagaaga aagttccagt tgagaaacac
    49141 tacactgagg ttggtcacat catcaatgcc ttctttgaag agtttgttga agaaacttta
    49201 atccaaccaa cctttgtcta tggacatcca gtagctgtat ctccactcgc taagaaaaat
    49261 cctgaagacc aacgctttac tgaccgtttc gagctcttta tcatgactaa ggagtacggt
    49321 aatgccttta ctgagttgaa cgacccaatc gaccaactta gccgttttga agcccaagct
    49381 aaagccaaag aacttggtga tgatgaagcg acaggaatcg actatgacta cattgaagct
    49441 cttgaatacg gtatgccacc aacaggtggt ttgggaatcg gtatcgaccg tctctgcatg
    49501 ctcctcactg atacaacaac tatccgtgat gtattgctct tcccaacaat gaaataaatt
    49561 cttatcctct ggctcttacc aggggatttt ttgattcaaa aagagactga atttaaggag
    49621 aaaatgaagt gtagtatatt gaagttgaaa tagtacactt tgatttctaa gacattgtta
    49681 gaaattggtt taaattccct aagcaatttg tgcatgtttt atttcatttt acgatagtac
    49741 gctgaaactg ttcaaaaagt actagaaatt gacttggatt ccccaattga tttgttcaga
    49801 ttcactataa ataaaaaatt aataagtggg ataggaagtt agcgtcaact aggatagtat
    49861 cttgcttaaa cagtatatat gggactgata taagtccata ggtcctatta gaggatgttc
    49921 tggtgtctta ttcacttgtt tttttatagt attagtagat agaatccgca aataaaaaag
    49981 tagttcaaat gcctggcagc aaaaaatctc aacgattcac ttaatataga ctaaagttta
    50041 gagtttaagg aaagtagggc tagtatattg tatgaaaaaa taagatggtt tttaagcaaa
    50101 actcttgaaa atgattgaaa aaagagttat tatagttgtg tagtaaaaag caaacgctta
    50161 cttaatcgag gagggcattt tatgtcatat aaaacaagca atgcagaagg tcatgtagac
    50221 ttcatcaata cctatgattt ggagccaatg gcgcaacaag ttattcctaa agcagcattt
    50281 ggctatatcg ctagtggggc ggaagatact ttcactttaa gagagaatat ccgcgccttt
    50341 aaccacaaac tcatcgttcc tcatacactt tgcgatgttg aaaatccaag tacagagatt
    50401 gaatttgcag gtgaaaaact atcttcgcca atcattatgg cacctgttgc ggctcataaa
    50461 ttggcaaatg aacaggggga agtggcgact gcgcgtggtg tgcatgagtt tggttctctt
    50521 tatacaacca gttcttactc tactgttgac cttccagaga tttctgaagc ccttcaaggg
    50581 acacctcatt ggtttcaatt ttactttagt aaggatgacg gtatcaaccg ccacatcatg
    50641 gaccgtgtga aggctgaagg ttataaagcg attgtcttga cggcagatgc tactgtaggg
    50701 gggaatcgtg aagtggataa gcgtaatggt tttgtcttcc cagttggcat gccgattgtt
    50761 gaagaatacc tgccagaagg tgctggtaaa tcaatggact ttgtttacaa atcagctaaa
    50821 caacgcttgt ctccacgcga tgtagaattt atcgctgaat actctggtct tcctgtgtat
    50881 gtcaagggac cacaatgccg tgaggacgtt gaacgttcac ttgctgcagg agcttctggt
    50941 atctgggtaa ccaaccacgg tggtcgtcaa atcgacggtg gaccagctgc ctttgactcg
    51001 cttcaagaag tggcagaagc agttgataga cgtgtgccga ttgtctttga ctctggtgtt
    51061 cgtcgtggtc aacacgtctt taaagccttg gcttcaggag cagacttggt agctattggt
    51121 cgccctgtta tttatggctt ggctctcggt ggtagtgtcg gtgtgcgtca agtctttgaa
    51181 cacttgaatg cggaattgaa gacagttatg caattgtctg gagctcagac cattgaagat
    51241 gtcaaacact ttaagctccg tcacaatcca tacaacccaa ccttcccagt tgaccctcgt
    51301 gacttaaaat tgtattgata aaacagattg ccttcactga atgtggaggt ttttcttcgt
    51361 gtattggaag aataaatcgc tatcgaaaac tatagtaaaa tgaaataaga ataggacaaa
    51421 tcaatcagga cagttaaatc gatttctaac aatgttttag aagtagaggt gtactattct
    51481 agtttcaata tattatatat aaagatattt ttcggtcaaa tatcttgcta gggctttcat
    51541 tttttgctat actggttcag taattaaata atagagacat ttggggtgct ttaggctgag
    51601 ataataccca ttgaacctga tacagttaag actggcgaag ggaaatgtga acagtttttt
    51661 cgtatggtga aatgaacggt ctaatcttgt aagtcaactc taattcttga ttgtaattgg
    51721 agttttttgt ttatataaac tggataggct tgtttagtta gctctctgta aatgctctcg
    51781 atgtgcttta aaaggatcaa gtggaattac gattttgctt gatatttctt gctgttttat
    51841 taattactaa caagtaaaga gaggagaagt aaatatggaa acacaagact atgcatttca
    51901 gccaggtttg actgttggag aattattaaa aagcagtcag aaggattggc aggctgcaat
    51961 caatcatcgt tttgttaagg aactttttgc ggggacaatt gagaataagg tcttaaagga
    52021 ctatctgatt caagattatc acttctttga tgccttctta tccatgctgg gtgcctgcgt
    52081 agctcacgca gataaacttg aatccaagct tcgttttgcc aagcaactag gctttcttga
    52141 agcagatgaa gatggttatt tccaaaaggc ttttaaagag ttaaaagtag cagagaatga
    52201 ctatctagaa gtgactttgc accctgtaac aaaagccttt caggatctaa tgtattcggc
    52261 ggtggcttca tcagactatg cccatctttt ggtcatgctg gtcattgcag aaggtctcta
    52321 tttagactgg ggttctaaag atttggctct acctgaagtc tatattcatt cggaatggat
    52381 caatctccac agaggtcctt tctttgcaga gtgggttcaa tttctggttg acgaactcaa
    52441 tcgtgtcggt aaaaatcgag aagatttgac agaacttcag caacgctgga atcaagcagt
    52501 cgctttagaa ttagcttttt ttgatattgg ttacgatgtc tagagaaggc tcatgatatt
    52561 tacaaatttg atgaggtaag actcttcgaa aatctcttca aaccatgtca gtttcacctt
    52621 gccgtaggta tggttactga cttcgtcagt tctatccaca acctcaaaac agtgttttga
    52681 gctgacttcg tcagtcttat ctacaggctc aaagcagtgt tttgagcaac ctgcggttag
    52741 cctcctagtt tgctctttga ttttcattga gtataaatca ttcaacgtaa atgaaaaaaa
    52801 tttcttaacg aaagatagag ataaatcgaa atcagtagat cgtataaagt gtaaaggaag
    52861 gatttcaata tgacaagttt aaaattatta aaagaaaaag caccattggt catttgtata
    52921 accaatgatg tagtaaaaaa tttcacagca aatggattag tagcactgag cgtctcacca
    52981 gccatgagtg agtttccagc agatttagag gatttgttaa agtatgctgg tggtttatta
    53041 ataaacatag gaacattgac agatgaaaat tggaaattat accaagctgc tctgaaaatt
    53101 gcggagaaat ataatgtccc agcagtttta gatcctgtag cctgtggagc aggagaatat
    53161 agaaaaaaag tagcagatga tctaatcaac aattataaac tagcagcgat tagaggaaat
    53221 gctggcgaga ttgcctcttt agtaggaata gatgtggcat ctaaaggagt agatagtgcg
    53281 ggcgtagata atattgacga aattgctcta gcagcaaatg agaagttcaa tattccaata
    53341 gtagtaacag gtgaagtgga tgccattgct gttaatggag aagtggtaac gattcataat
    53401 ggtagtgcta tgatgccgaa agtcattggg acaggatgct tattaggagc tgtagtagca
    53461 agttttatcg gactggaaaa aggtcaagaa ttaaaatcat tagaaacagc aatgttagtt
    53521 tacaatatcg ctggagaaat ggcagaaaaa cgtccaaatg gacatcttcc tgggacattt
    53581 aaagttgaat ttataaatgc cttatacgag attacagatg aagatgtaaa ggaattcaaa
    53641 agagtgaagt aagatgtttc ataaagaatt actaaaacta tattttattt gtggaacgac
    53701 tacttgccaa ggaaaaaatc tatatacagt cgttgaggaa gccttaaaag gtggtataac
    53761 cttatttcaa tttcgagaaa aaggtgaggg tgctttagaa ggcttagaaa aacttgagct
    53821 agctatccaa attaaagaac tttgtaaaaa atacaatgtt ccatttatcg ttaatgacga
    53881 tatagattta gcaatggaaa ttgacgccga tggcgtacat gtaggtcaag atgatattgg
    53941 tgttgatgaa attagaaaat tgatgccaga taaaataatt ggtctttcta taagaaacga
    54001 agaagaattt caacaatcaa aagttgaata tgtagattat gtaggtgttg ggcctgtatt
    54061 tgatacccag tcaaaagatg atgctggtgg tgctataggt tatgaaggtc ttgaattgat
    54121 gagaaaacta ttgccacaaa tgcctttagt tgcaattggt gggatacaga cgaaacatat
    54181 taaagacatt ataaagacca atgttgacgg cgtttcaatc atttcggcaa tatcgtatgc
    54241 aaaaaatata gaaaaaactg ttcgggaaat gagtgaacaa tagatatcta tccttggatt
    54301 ctaagtaagt aggattttcc ttttttaaaa aactatgtct agattcagct tgaatggcta
    54361 attcatcaaa caggtcattt gttttttgca aaagaaagat ctgctgtctt tgtgagtgca
    54421 aggctgtatt tccagttcaa tttcttgaac tagtataaaa tgtgtgttat aataatcaca
    54481 taattaaata ataaaggcat ttggggtgct ttaggctgag atgataccca ttgaacctga
    54541 tacagttaag actggcgaag ggaaatgtga aatgtttttt tcgtatgtcg aaaagaactg
    54601 tctaatcttg taagctgaac tctaattcgt atctgtaatt agagtttttt cttttacgaa
    54661 actggatgaa gatgatatag tagattgaaa taagatgcga acaaatcaat tagaaaattc
    54721 aaattaattt ctagaaatat tttagcattc ctgtgtactg ttctaaattc aatctgctat
    54781 acaaagtatt taggtcggtc ttcttgagtg ccccactttt cttttaaaaa aggagttttt
    54841 tatgttgaaa aaatggcagt taaaagatgt tatcttgctt gctttcttgt ctatcttttt
    54901 tggtggggtt ttcgttggtt caggatatgt gtataatatt ctcagtctac tcttaacacc
    54961 tcttggtttg caggcctttg ccaatgaaat cctcttcggt ctctggtgta tggctgcgcc
    55021 cattgctgcc atctttgttc cgagagtcgg aagtgcaacg attggagaag tgctagctgc
    55081 gcttgctgaa gtcctttatg gtagccaatt tggtctagga gctcttttgt ctggcttggt
    55141 tcaaggtttg ggaagtgaat ttggttttat cgtaactaag aatcgctatg aaagttggct
    55201 ctctctaact gctaatagta ttgggattac gcttgttagc tttgtctatg aatacattaa
    55261 gttaggttac tacgcctttt cccttccgtt tgtcctttcc ttacttgtgg tacgttttat
    55321 ttctgtttat ttcttctgta ccatcttggt tcgtgccatt gtcaaactct atcatcagtt
    55381 tgcaactgga ggaaaagcat agatgggtct ggaactacga gcgattcagt ccccaatctt
    55441 ctctgagccg tttgatttta cttttcatgc gcaagccttt accttgttag ttgggagcag
    55501 tggttcagga aaatccagcc tttttcaagt cattgcccaa gtcagttctc ttccctatag
    55561 tggtcaagtc ctgatagatg ggagcgaggt cagtcagctt tctatcatcg cacgtgtcca
    55621 gaaggttggc attctctttc aaaatcccaa tcatcaattt accatggaga acttgtttga
    55681 ggagctgatt ttcaccttgg agaatatcgg ctatcacctt caggaaattg attctaaaat
    55741 agcagaggtt gtccagcaat gtcgttgcga ggcaatctta caccgtccca ttcatcacct
    55801 atcaggtggg gaaaagcaaa aagcagcgat ggctgtcctc tttgccatga atcctagggt
    55861 atatctcttg gatgagccct tcgcttccat tgaccgcaag agcagaatcg agatattgga
    55921 gattctaaaa gagttggctc ttgatgggaa gacagttatt ttgtgcgacc atgatttatc
    55981 tgactataaa gcctatatcg accatatggt tgagctaaga gacggaaaac taagggaagt
    56041 gtttcaaatc ccttcctatg agatgacaca ggttgcttca aaggaagttg cttctagccc
    56101 ggaactattc catatggata gaacgacttg tgagtttgga aatcgctccc tcttttcgat
    56161 tgctgatttt acattttacc aaggaatttc ctgtatcctg ggtgacaatg gtgttgggaa
    56221 atcaaccctc tttcggtcta ttcttcaatt tcaaaagtat aaggggcgca ttgcatggaa
    56281 ggggacagtc ctgaaaaaga aaaagagttt gtaccgtgaa ctgacgagta ttgttcagga
    56341 agctgagaag cagtttatcc gagtcagtct gcgagaggag cttcgattag atggacctga
    56401 ttctgaaaga aatcagcgga tttttcaagc tttacgatat tttgatttgg agcaggcagt
    56461 cgataagagt ccctatcaat taagtggtgg tcagcaaaaa attcttcagc tcttgaccat
    56521 cttgaccagt aaggcttccg tgatcttgct agatgaacct tttgcaggtt tggatgatag
    56581 agcctgccat tatttttgca agtggattgt ggaggagagg aatcaaggaa gaagttttct
    56641 gctcattagt catcgtttag accctttgat ttctgtggtt gattattgga ttgagatgac
    56701 tagtcagggt cttcggcatg tgaaagaagt gaccattacc aaaccactta catctcagag
    56761 tagcaatacc caaggggagg tgagatagta tggtcaaagt agcaacccag acaccgatta
    56821 tcagtctctt cttgctgatt ttatccttgg aaacatcttt cattccttcg attgctctga
    56881 atctttcggt agtcgcattt tgtattctct ttatgctcta ttaccgtcga tttaaaatgt
    56941 tagcttggat gatcatactt gccattttac catcttttgc caactactgg gcagttcagt
    57001 tacacggaga tgcttcacag gcagtcatgc ttggaacgag ggcctttgtg acagtttgta
    57061 tcggccttgt ctttgtttcc tctatttcac taaaagagct tctcttgtac ttggctcaaa
    57121 aggggctatc acgctcttgg tcctatgcct tgattgtggt attcaattct tttcctctca
    57181 ttcagcaaga aatcaagtcc ctcaaagaag cttgcctatt acgtggtcaa gaactacatt
    57241 tttggtcgcc cttgatttac agtaaggttc tgatgacagt ctttaggtgg cgccatcttt
    57301 acctgagagc tctatctgct cacggatatg acgaacatgc acagttgaag aatagctatc
    57361 ggacttttta tattcctaaa aaaacaaaat taatctacct gcttttcttt ttattgcttc
    57421 aaaccagtct atttttataa aggagttatt atggaattta cagatattgc gatggaatta
    57481 tccaagaaag cttggcaggc ttcctttcat catcccttta ttttacaatt acaagagggg
    57541 aatttagaac ctgccatttt ccgctattac ctgattcagg atgcctacta tctgaaggct
    57601 ttctcagaaa tctatcatct tttggctgat aagacttcaa accaagagat gaaaagactc
    57661 ttgaagcaaa atgctcaggg tttagtggag ggtgagttat ttattcgcca acaatttttc
    57721 aaggaattgg aaatcaacga ccaggaaatg gagcaacatc caatcgctcc aacctgttat
    57781 cattacattt ctcatattta taggcaattt gcagaaccga acttagccat agcttttgca
    57841 agcttgcttc cttgtccttg gttataccat gatataggca aatcacttaa tcttaaacca
    57901 tcaccaaatc ctctctatca acaatggatt gaaacttata ttacggatga gttagagcaa
    57961 cagatcagag aggagggagc actggtcaat cagctctatc gagaaagtga tgagacagat
    58021 aagcaaaaaa tgctagatgc cttccacatc agtgttcata tggaagccaa gttttgggag
    58081 atggcttacc aacaccagac atggaagagc gatttacagt ctttagaaaa aggagaagaa
    58141 tagaaacatg agaaagcacc aactacaagt tcacaaattg accattttat ctatgatgat
    58201 tgcccttgat gtagtcctta cacctatctt tcgaattgag ggaatggcac cgatgtccag
    58261 tgtagtcaat attctagcag gaatcatgat gggacctgtt tatgccttgg ctatggctac
    58321 agtcacagcc tttatccgta tgacgactca agggattccg cctttagctc tcacaggagc
    58381 gacttttgga gcccttctag caggtctctt ttataagtac ggtcgaaaat ttcactattc
    58441 tgctctagga gagattttgg gaacaggtat tattggttcc attgtttcct atcctgttat
    58501 ggtactcttt acaggatcag ctgctaagct tagctggttt atctacacgc ctcgattttt
    58561 cggagcaacc ttgattggta cagcgatttc ctttattgcc tttcgatttt taatcaagca
    58621 ggaattcttt aaaaaagtgc agggatattt ctttagtgaa aggatagact gatgcaggaa
    58681 tttacaaatc cctttcctat aggctctagt tccctcattc actgcattac caatgagatt
    58741 tcttgtgaga tgctggcaaa tgggattttg gctctgggat gcaaacctgt catggcagat
    58801 gattcccgtg aagttcttga ttttactaag caaagtcagg ctctcttcat caatttgggg
    58861 catttgtcag ctgagaagga aaaagcaatc cgcatggcag cttcgtatgc aaaccaatct
    58921 tctctcccga tggtagtaga tgcggttggc gtaacgactt catccattcg taagagctta
    58981 gttaaagacc ttttagacta tagacctacg gtccttaaag gaaacatgtc agaaattcga
    59041 agtcttgttg gattaaagca ccacggcgtt ggggtcgatg cgagtgctaa agatcaagaa
    59101 acggaggatt tgcttcaagt cttgaaagac tggtgtcaga cctatcctgg tatgtctttc
    59161 ttagtcacag gtcccaagga cctcgtcgtt tcgaaaaatc aggtcgctgt actgggaaat
    59221 ggctgtactg aattagactg gataacaggg acaggagact tggttggagc cttaacagct
    59281 gtttttctca gccaaggaaa gactggtttt gaagcttctt gcttagcagt ctcttatctc
    59341 aatatcgctg ctgagaaaat agttgttcaa ggaatgggat tggaagaatt tcgttaccaa
    59401 gtactcaatc agctttcgct cctaagaaga gatgaaaatt ggctagatac catcaaagga
    59461 gaggtttatg aatagagaag cacttagact atatctggta accaatcgct atcaagattc
    59521 cgtggaaagc tttcttgcaa aagttgagac ggcctgccgt tcaggggtta ccatagtcca
    59581 attgcgagaa aaaaatctca caaccaatca atattatcaa ctggcaaaac aagtcaagga
    59641 aataacagat gcttatcagg tacccttgat aatcgatgat cggttggatg tttgtcttgc
    59701 ggttgatgca gcaggtctgc atatcggaga tgatgaatta ccagtttcgg tagctcgcaa
    59761 agtcttgggt cctgaaaaaa tcctcggtgt caccgctaaa acggttaaaa gagctctgga
    59821 agcggagaaa tcaggtgcag attacttggg tacaggagcc attttcccaa ccaccaccaa
    59881 ggaaaatgcg cccattactc tgatatcgac cttgaaaaca atttgccaaa cggttgccat
    59941 tccagtagtt gctattggag gcttgacttc ggagaatatt gatcagctta tgggcactgg
    60001 catagctggt gtagctgttg tacgtgattt gatgcaagca gaagatattg aggcaaaaac
    60061 gcaagccttt ttaaaaaagt tgcataacat tctttcctaa ttaatactca atgaaaatca
    60121 aagagtaaac tagaaagcta gtcgcaggtt gctcaaagta ctgccttgag gttttagata
    60181 agactgacga agtcagctca aaacagtgtt ttgaggctgc agatggaagc tgacgtagtt
    60241 tgaagagatt ttcgaagagt ataaaaactc tctaattccc ttaaagtggg aactagagag
    60301 ttttttttct taatctttaa aagttgtatg gttgactgga ccagaaccat gaccgagttg
    60361 aggggcatct tgaatagctt ttgtgataaa ggccttggcc ttatcaactg cctggtaaag
    60421 actcttgccc ttggctagtt cagcagtaat cactgcagca aaggtacatc cagtaccatg
    60481 ggtgtgacag gtttgaattc gtgggctttc ccagacaaat tgttcattct tggtaaagag
    60541 gaaatcttta gcaccacctt tgagatgtcc gcctttgata accacagact gaggaccaaa
    60601 ttcttttaaa atcaggcgac cagcacgctg catgtcttcg gggtcatgga ttgaaaaacc
    60661 aacaatctct tctgcttcag gaagatttgg cgtaataata gttgctagag gtagtaagtt
    60721 tgttttgaga tagtctctag cacttgagtc aatcaaggca tctccacttg tagcaaccat
    60781 aacaggatca aggacatagg gacaatccag ttttttaaga tagggttgga tgatttccat
    60841 gatttcagta gtagccaaca ttccagtttt tacagcctga ggtggaatat cagaaaagat
    60901 actctccaat tgggctttca acatttgagg agaaacgtgc tcgattagct gaacacctct
    60961 ggtattttga gcgacaagac tggttacaac agccattcca tagacatctc tcgcttggaa
    61021 tgactttaaa tctgccataa tgccagcacc accactaggg tcagtccctg caatggtcaa
    61081 agcaacgggt aaataagtca tctaaaacct cccaaccaac tgaagtttgt attcttaaga
    61141 acaagctagt ctgttttaga aaggcaatag aagactgcta gtccccatta tcatttccac
    61201 ttccatcagc tagcattacc tagattgagt cagagggatc taacagtcgt taatctcagc
    61261 tttacgcacc cctagtggtt gttttctttt ttctttagta tagcatattt ttattgttta
    61321 tatagtaata tttgactgca aatcgttttt caaatgatta aaattctatt tttcgaagaa
    61381 aatattattt ctataattga caaatgtaga ttttaagagt atactgatga gtgtaattga
    61441 caaacgtaga ttttggaggt atggtaatgc agatttcaga tgcagaatgg caggtcatga
    61501 agattatttg gatgcagggg gagcagacca gtacagattt gattagggtt ttggcagagc
    61561 ggttcgactg gtccaagtca acggttcaga cacttttgtc tcggctggtt gagaaagagt
    61621 gtttgactcg gaaaaaagaa ggcaagtcct ttgtttattc agccctttta actctagacc
    61681 aaagtcggga tttacttgtc caagatatca aagacaaggt ttgttcccgt aggattagga
    61741 atttgttggc tgacttgatt gtagaatgtg aatttactca gactgacttg gaagacttgg
    61801 aagctgtgat ttcagagaag aaatcaagtg ctgtaacaga agtaagatgt aattgtatgt
    61861 aaaggagacg tcatgttaaa tagtattgta accattattt gtattgccct tatcgcgttt
    61921 atcttgtttt ggtttttcaa aaagcctgaa aaatctggac aaaaagccca gcaaaaaaac
    61981 ggataccaag agattcgagt ggaagtcatg ggaggctata ctcctgagtt gattgtcctc
    62041 aagaaatcag tgccagcccg cattgtcttt gaccgcaagg atccttcacc atgtctggat
    62101 caaattgttt ttccagattt tggtgtacat gcgaacctgc caatggggga agagtatgta
    62161 gtggaaatca cgcctgaaca ggctggagag tttagctttg cttgtggtat gaacatgatg
    62221 cacggcaaga tgattgtaga gtaggtggag actatgacag aaattgtgaa agcaagctta
    62281 gaaaatggca ttcaaaaaat ccgtatccaa gctgaaaaag gctatcatcc agcccatatc
    62341 cagcttcaaa agggaattcc agctgagatt acctttcatc gtgctactcc ttcaaactgt
    62401 tataaggaaa ttctgtttga agaagaaggt atcttggaac caatcggcgt agatgaggag
    62461 aaagtcattc gttttacacc tcaagaatta gggcgacatg aattttcttg tggcatgaag
    62521 atgcaaaagg gaagctatac agtcgttgag aagactcgaa aatctctatc tctcctgcaa
    62581 cgtttttgga ttactagtat ctttactgtg cctcttgtga ttctcatgat tgggatgttg
    62641 acaggtagca ttagtcatca agtcatgcat tggggaacct ttctagcaac aacgcctatt
    62701 atgttagttg caggtaagcc atatatccag agtgcttggg ccagttttaa aaagcacaat
    62761 gccaacatgg ataccttggt tgcgctggga actctagtgg cttatttcta tagcctagtt
    62821 gctctctttg ctggtctccc tgtttacttc gaaagtgctg gatttatcct ctttttcgtt
    62881 cttttgggag cagtttttga ggaaaaaatg agaaaaaata cgtcccaagc tgtggagaaa
    62941 ttactggact tgcaagctaa aaccgcagaa gtcttgagtg atgatagtta tgtccaagtt
    63001 cctttggaac aagtcaaggt aggcgacctg attcgagtgc gtcccggtga aaagattgct
    63061 gttgatggtg tcgtagtaga aggtgtctct agtattgacg aatccatggt gacaggtgag
    63121 agtctgcctg tggacaagac agttggagat actgtcattg gctcaaccat caatcatagt
    63181 ggaacgcttg tctttagagc agaaaaagtt ggctcagaga ctgttttggc tcagattgtg
    63241 gattttgtga agaaagctca gacaagtcgt gcgccgattc aggacttgac ggataagatt
    63301 tcagggattt ttgtcccagt agttgtcatt ttaggaatca tgaccttttg ggtttggttc
    63361 gtcttgctca gggatagtgt ggtcgtgctt ggagctagct ttgtgtcctc tcttctctac
    63421 ggagtggcgg ttttgattat cgcctgtcct tgtgccttgg gacttgcaac accgacagcc
    63481 cttatggtgg ggacaggacg tagtgccaag atgggggttc tcctcaaaaa tggaactgtc
    63541 ttacaggaaa tccagaaagt tcaaactctt gtctttgata agaccgggac tttgacggaa
    63601 gggaaacctg tggtaacaga tatcatcggc gacgaagtag aagtgtttgg attggcagcc
    63661 tccttggaag atgcttctca acacccactg gctgaggcta tcgttaagcg agcgagtgaa
    63721 gctggacttg agtttcaaac tgttgaaaat tttcaggcct tgcacgggaa aggtgtttca
    63781 gggcgaatca atggaaaaca agttttactt ggaaatgcta aaatgctgga tggcatggat
    63841 atttctaata cttatcaaga taaactagaa gaactagaaa aagaagctaa gacagttgtg
    63901 tttttagctg ttgacaatga aatcaaaggc ttgcttgctt tgcaagatat tcctaaggaa
    63961 aatgctaagc tagccatcag tcagctaaaa aaacgtggtc tccgaacagt catgctgaca
    64021 ggagacaatg ctggtgtggc gcgtgctatt gcagatcaaa tcggaattga agaggtcatt
    64081 gcaggcgtct tgccagaaga aaaagcccat gaaatccata aactgcaagc ggctggcaaa
    64141 gtagcctttg ttggggacgg tatcaatgac gctcctgccc ttagtgtagc agatgtggga
    64201 attgctatgg gtgctggaac agatatcgcc atcgagtcag cagatttggt gttgacaacc
    64261 aataatcttt taggagtggt tcgtgccttt gatatgagta agaaaacctt tcatcgaatt
    64321 ctactcaatc ttttctgggc ttttatctac aatgttgtcg gaattccgat tgcagcagga
    64381 gtcttttcag gtgttggact ggctctcaac ccagaattgg caggtctagc catggccttt
    64441 agttctgtat ctgttctgac cagttccctt ctgttaaatt ttagtaaaat agactaaaag
    64501 taatgactag atttctttgt tataaaacag aaatgacaac actttcaaaa ctgtattaga
    64561 atagagaata gagagttttg agcagatttt tagaaaagtc agcataaata tgatacagtg
    64621 gaatagtaaa aatttggaga acgtttccaa ttctatgtaa tcgtattctc caagtttaaa
    64681 aaaattgaag gagagttatc attatgactc aagggaaaat tactgcatct gcagcaatgc
    64741 ttaacgtatt gaaaacatgg ggcgtagata caatctacgg tatcccatca ggaacactca
    64801 gctcattgat ggacgctttg gctgaagaca aagatatccg cttcttacaa gttcgccacg
    64861 aagagacagg tgctcttgca gcggttatgc aagctaaatt cggcggctca atcggggttg
    64921 cagttggttc aggtggtcca ggtgcgactc acttgattaa cggtgtttac gatgcagcta
    64981 tggataacac tccattccta gcgatccttg gatcacgtcc agttaacgaa ttgaacatgg
    65041 atgctttcca agagcttaac caaaacccaa tgtacaacgg tatcgctgtt tacaacaaac
    65101 gtgtagctta cgctgagcaa ttgccaaaag taattgacga agcctgccgt gctgcaattt
    65161 ctaaaaaagg tccagctgtt gttgaaattc cagtaaactt cggtttccaa gaaatcgacg
    65221 aaaactcata ctacggttca ggttcatacg aacgctcatt catcgctcct gctttgaacg
    65281 aagttgaaat cgacaaagct gttgaaatct tgaacaatgc tgaacgccca gttatctatg
    65341 ctggatttgg tggtgttaaa gctggtgaag tgattactga attgtcacgt aaaatcaaag
    65401 caccaatcat cacaactggt aaaaactttg aagctttcga atggaactat gaaggtttga
    65461 caggttctgc ttaccgtgtt ggttggaaac cagccaacga agtggtcttt gaagcagaca
    65521 cagttctttt ccttggttca aacttcccat ttgctgaagt ttacgaagca ttcaagaaca
    65581 ctgaaaaatt catccaagtc gatatcgacc cttacaaact tggtaaacgt catgcccttg
    65641 acgcttcaat ccttggtgat gctggtcaag cagctaaagc tatccttgac aaagtaaacc
    65701 cagttgaatc aactccatgg tggcgtgcaa acgttaagaa caaccaaaac tggcgtgatt
    65761 acatgaacaa actcgaaggt aaaactgagg gtgaattgca attgtatcaa gtttacaatg
    65821 caatcaacaa acatgctgat caagacgcta tctactcaat cgacgtaggt aacactactc
    65881 aaacatctac tcgtcacctt cacatgacac ctaagaatat gtggcgtaca tctccgctct
    65941 ttgcgacaat gggtattgcc cttcctggtg gtatcgctgc taagaaagac aatccagatc
    66001 gccaagtatg gaacatcatg ggtgatggag cattcaacat gtgctaccca gacgttatca
    66061 caaacgttca atacgacctt ccagttatca accttgtctt ctcaaatgct gagtacggct
    66121 tcatcaagaa caaatacgaa gatacaaaca aacacttgtt tggtgtagac ttcacaaacg
    66181 ctgactacgc taaaattgcg gaagctcaag gagctgttgg attcacagtt gaccgtatcg
    66241 aagacatcga tgcagttgtt gcagaagctg ttaaattgaa caaagaaggt aaaactgttg
    66301 tcatcgatgc tcgcatcact caacaccgtc cacttccagt agaagtactt gaattggatc
    66361 caaaacttca ctcagaagaa gctatcaaag ccttcaagga aaaatacgaa gcagaagaac
    66421 tcgtaccatt ccgtctcttc ttggaagaag aaggattgca atcacgcgca attaaataat
    66481 tcctctcgcc gaaaatcaaa tatgaaactt gtagacttta ttctttgatt ttcatagagc
    66541 agaactttaa aagatgactc tttgtcaact gtagtgggtt gaaaaa
//
LOCUS       DAVHBD010000004        64286 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000004 DAVHBD010000000
VERSION     DAVHBD010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64286
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.004"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(395..1741)
                     /gene="gdhA"
                     /locus_tag="VVK04_000263"
     CDS             complement(395..1741)
                     /gene="gdhA"
                     /locus_tag="VVK04_000263"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU3988972.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLKQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            2277..2829
                     /locus_tag="VVK04_000264"
                     /pseudo
     CDS             2277..2829
                     /locus_tag="VVK04_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2826..3044
                     /locus_tag="VVK04_000265"
     CDS             2826..3044
                     /locus_tag="VVK04_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3988973.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(3101..3385)
                     /locus_tag="VVK04_000266"
     CDS             complement(3101..3385)
                     /locus_tag="VVK04_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU3988974.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3439..4374)
                     /locus_tag="VVK04_000267"
     CDS             complement(3439..4374)
                     /locus_tag="VVK04_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU3988975.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            4478..4921
                     /locus_tag="VVK04_000268"
     CDS             4478..4921
                     /locus_tag="VVK04_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU3988976.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            5037..5303
                     /locus_tag="VVK04_000269"
     CDS             5037..5303
                     /locus_tag="VVK04_000269"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU3988977.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            5300..5674
                     /gene="crcB"
                     /locus_tag="VVK04_000270"
     CDS             5300..5674
                     /gene="crcB"
                     /locus_tag="VVK04_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU3988978.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            5668..5997
                     /gene="crcB"
                     /locus_tag="VVK04_000271"
     CDS             5668..5997
                     /gene="crcB"
                     /locus_tag="VVK04_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU3988979.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            6116..6463
                     /gene="rplS"
                     /locus_tag="VVK04_000272"
     CDS             6116..6463
                     /gene="rplS"
                     /locus_tag="VVK04_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU3988980.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            6506..6577
                     /locus_tag="VVK04_000273"
     tRNA            6506..6577
                     /locus_tag="VVK04_000273"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6539..6541,aa:Arg,seq:cct)
     gene            complement(6633..7439)
                     /gene="yidA"
                     /locus_tag="VVK04_000274"
     CDS             complement(6633..7439)
                     /gene="yidA"
                     /locus_tag="VVK04_000274"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU3988981.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LSVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(7452..8756)
                     /locus_tag="VVK04_000275"
     CDS             complement(7452..8756)
                     /locus_tag="VVK04_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU3988982.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSLHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            8828..9205
                     /locus_tag="VVK04_000276"
     CDS             8828..9205
                     /locus_tag="VVK04_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU3988983.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            9427..11577
                     /locus_tag="VVK04_000277"
     CDS             9427..11577
                     /locus_tag="VVK04_000277"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HEU3988984.1"
                     /translation="MLKTQEIADKYGITRQTLNNWMQKGIISQPRKNNRSAYEWEEEN
                     EKEIVRVISEEIPAKYYVSNKETLKIGNRRYLGSKQKMLDFILKTVSENIGSIDSVAD
                     IFGGTGVVADLFRKQNKKVIVNDILYSNFVSFQTWFSNEDVDIHKVSHIIDELNNLSP
                     KKGYVSKNFGGAYFSEENAGKIDSIREEIEKYKSGNQREYFMLLTSLLYAMDKVANTV
                     GHYDAYRKKMDYCKEIYLRVPEYNENNQNEIYNKDANKLVKEIYADLVYIDTPYNSRG
                     YENAYHVLENIAEWKKPDVEGVAKKAVNRSEKGSDYTKSKAPQAFEDLILNINAKYIL
                     VSYNNMNKKGNSRSNAKISNEEIIKILSKRGKVQVFETDFSPFTTGKSKIENHKELLY
                     LCIISPEKKKEKKLIKSALNYTGGKYKLLPQLLPLFPESYNNFIDLFSGGATVAVNLA
                     NINKSKTKKYIINDISEEVIDFYKYLESQKDVTVFLDKVEKAIEFYKLSNTQKYSYAH
                     YGVNSSTGLGSYNKEAFLKLRQDYNKKNYNKFDKEVLFYLLIVFGFNNQIRFNNKGEY
                     NLPVGKRDFNANMKSKLITFIQGLQNYNFVIQSCDFRKTMNQVNKGDFVYTDPPYRIT
                     TAAYNENGAWTLKDDLDLFKYLDSINDKGAYFALSNVVIHNNKENKELMKWASKYNLH
                     VLDYHYNNSNYQSKAKMSNTVEVLITNYNSKGDI"
     gene            11574..13586
                     /locus_tag="VVK04_000278"
     CDS             11574..13586
                     /locus_tag="VVK04_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="HEU3988985.1"
                     /translation="MRLKESTSIFNMGDTSIRVKEVVPIYKQILKTLQKHNQSNQKWN
                     NESQASFYSSVLSDFAKAETEDGINLFGNLNRNEITGLDKRGRTLTNALVKIGFINYD
                     RKLSQVGLNYISETEQAFDKLEELFGLTIDNLVYFRQLLKLRIYDSNSDKYFYNFRFA
                     LAFLNRYSKVPVRDFLWIVESIKPNFSEEKIKVIIDNYQSVYDNNKTFEQYRDEEFAN
                     HILIPERVDEARKMFSIKNFSDENFKKLFPNRKNSNKSLEYKSFVLSIINFTEEKTER
                     SFEEMMSLSKQDAIKKAFGDGKAVFKYKNKDSIQDFITKNSDNPLLSGQYLDIYYAFT
                     WSKHNDLIKEYSDMCKRIFSLSGVISFNQGIVSLGRPWIFPKLFSLLNGNFKISGEAS
                     YEEYENDIKSSFYQDICISDILELSYTQVLEIQNQIAEEFGIADISNIKQFVADKQER
                     EFREFVEQEFGITKVSEVLSFISQRNDKKVQELVTDNALVPTIFEYILAIAWYYISDK
                     KFQLRKSMQLTFSADNLPLSHAGGNKGDIEIEYSDKMLLLEATLMDKSTQKRGELEPV
                     IRHSVNLALSTNKPLQTIFVANEVDDNVVNIFRATSFIQLNGTLTKGSVKGLNIFALT
                     IPEIINILDRKINEQRIFEKLDDFSTIEPYRIENGWREEIVSEILA"
     gene            13654..16215
                     /locus_tag="VVK04_000279"
     CDS             13654..16215
                     /locus_tag="VVK04_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEU3988986.1"
                     /translation="MIQRGSEFRKWDLHIHSPYTVLNNQFDKLPDGSPDVEKFIQKIK
                     DEGISAVGLTNYFRFSDDDFKLKDRLNEEGIATFLNLEVRLSNINKSDELFDYHVVFG
                     NEVQDDIVKNLLGHLKANIGDDEKSFNRLSKTEIEDKAHIPFKDLLKVLNSDRELNGR
                     FLTGFLSRGHGSATSDSDSKNKAVYEDICINSDFLIHSSNEVNITKDREFWLDKSPHI
                     RPLLQSSDSHSLEQIGSKYSWVKADLTFDGLEQIKYEPEYRISVEKEKPTLKKDELVI
                     DKILYNGQDIYLSENLNTIIGGRSTGKSTLLNSIAKKLGRELNGDSYYFENMDDFQII
                     WKDQQEDNSRQIEYIPQEYMFALARDNKKLKDLVGSIIQSKEMNSELKKYEQNCATLH
                     LEIRGLLDSYKENQKNIHELIKPEAEKQATQNRIKTYETKKKELLNASEITEQERDLF
                     ENKNKELQLLKTQKEIHESDLRYVSSILPITFEVESLPTTTTPSQDLRVKIGQITARL
                     RDSVRAQQEHEIRIIKLEKESLIKAIENKISDIGNDDIYKKCVEAMKNNSEIARLNSL
                     IKNEVDILAKIEAFEKQRDEFDKVTEEIQKEIISKYKEYSNIRTELLNNFKIEDDNGD
                     NLKISVKFSLIDLEAEFDYINARGRSKQDFIEKMIGSFEEVVDSIFDEDSLAFNGNRD
                     KFSHIEHFFTTNFYEYSFEIEYQGDKFEQMSPGKKAFIVLKLILEFSDSKIPVLIDQP
                     EDSLDNRAIYSELTKYIKKTKKNRQIIIVTHNPNIVVSGDAENIIVANQQSDNSPNQN
                     GKKFDYVNGALENRNNDSTSEFILQKYNIREHVCDILEGGEDAFIKRENKYSING"
     gene            16348..16680
                     /locus_tag="VVK04_000280"
     CDS             16348..16680
                     /locus_tag="VVK04_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU3988987.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            16692..18263
                     /gene="ffh"
                     /locus_tag="VVK04_000281"
     CDS             16692..18263
                     /gene="ffh"
                     /locus_tag="VVK04_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU3988988.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMSDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(18458..19741)
                     /locus_tag="VVK04_000282"
     CDS             complement(18458..19741)
                     /locus_tag="VVK04_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU3988989.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(20044..20757)
                     /gene="rsmG"
                     /locus_tag="VVK04_000283"
     CDS             complement(20044..20757)
                     /gene="rsmG"
                     /locus_tag="VVK04_000283"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU3988990.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            20851..21411
                     /locus_tag="VVK04_000284"
     CDS             20851..21411
                     /locus_tag="VVK04_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU3988991.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            21413..22312
                     /gene="htpX"
                     /locus_tag="VVK04_000285"
     CDS             21413..22312
                     /gene="htpX"
                     /locus_tag="VVK04_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU3988992.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(22356..23915)
                     /locus_tag="VVK04_000286"
     CDS             complement(22356..23915)
                     /locus_tag="VVK04_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU3988993.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            complement(24154..24471)
                     /locus_tag="VVK04_000287"
     CDS             complement(24154..24471)
                     /locus_tag="VVK04_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU3988994.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            24641..25183
                     /locus_tag="VVK04_000288"
     CDS             24641..25183
                     /locus_tag="VVK04_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU3988995.1"
                     /translation="MKLNIQEIRKQSEGLSFEQTLDLVDDLRARNQEILDVKDILAIG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            25183..25812
                     /gene="nth"
                     /locus_tag="VVK04_000289"
     CDS             25183..25812
                     /gene="nth"
                     /locus_tag="VVK04_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU3988996.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            26023..26544
                     /gene="pyrR"
                     /locus_tag="VVK04_000290"
     CDS             26023..26544
                     /gene="pyrR"
                     /locus_tag="VVK04_000290"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU3988997.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            26563..27486
                     /locus_tag="VVK04_000291"
     CDS             26563..27486
                     /locus_tag="VVK04_000291"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU3988998.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLQETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            27536..28615
                     /gene="carA"
                     /locus_tag="VVK04_000292"
     CDS             27536..28615
                     /gene="carA"
                     /locus_tag="VVK04_000292"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU3988999.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            28928..32104
                     /gene="carB"
                     /locus_tag="VVK04_000293"
     CDS             28928..32104
                     /gene="carB"
                     /locus_tag="VVK04_000293"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU3989000.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESIRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(32379..33188)
                     /locus_tag="VVK04_000294"
     CDS             complement(32379..33188)
                     /locus_tag="VVK04_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU3989001.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILIEFEGRMLPVPKKYDQFLTQMYGDYITPPSKEMQEWYSHSIKAYRKN"
     gene            complement(33190..33993)
                     /locus_tag="VVK04_000295"
     CDS             complement(33190..33993)
                     /locus_tag="VVK04_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU3989002.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(34003..35490)
                     /gene="tacF"
                     /locus_tag="VVK04_000296"
     CDS             complement(34003..35490)
                     /gene="tacF"
                     /locus_tag="VVK04_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU3989003.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            35846..36553
                     /locus_tag="VVK04_000297"
     CDS             35846..36553
                     /locus_tag="VVK04_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU3989004.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVLHAEDLVDKYLPLHKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIKLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            36558..37580
                     /locus_tag="VVK04_000298"
     CDS             36558..37580
                     /locus_tag="VVK04_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU3989005.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLL
                     LVGSSRSGRIDFENAIQMMKVKRFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            37597..38466
                     /gene="licA"
                     /locus_tag="VVK04_000299"
     CDS             37597..38466
                     /gene="licA"
                     /locus_tag="VVK04_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU3989006.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAQTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGTDEK"
     gene            38456..39334
                     /locus_tag="VVK04_000300"
     CDS             38456..39334
                     /locus_tag="VVK04_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU3989007.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            39346..40035
                     /locus_tag="VVK04_000301"
     CDS             39346..40035
                     /locus_tag="VVK04_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU3989008.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLIFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            40132..40980
                     /gene="dprA"
                     /locus_tag="VVK04_000302"
     CDS             40132..40980
                     /gene="dprA"
                     /locus_tag="VVK04_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU3989009.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            41864..42907
                     /locus_tag="VVK04_000303"
     CDS             41864..42907
                     /locus_tag="VVK04_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU3989010.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            43074..45161
                     /gene="topA"
                     /locus_tag="VVK04_000304"
     CDS             43074..45161
                     /gene="topA"
                     /locus_tag="VVK04_000304"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU3989011.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSTVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            45267..45626
                     /locus_tag="VVK04_000305"
     CDS             45267..45626
                     /locus_tag="VVK04_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU3989012.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            45719..46351
                     /locus_tag="VVK04_000306"
     CDS             45719..46351
                     /locus_tag="VVK04_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU3989013.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQLEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            46395..47051
                     /locus_tag="VVK04_000307"
     CDS             46395..47051
                     /locus_tag="VVK04_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU3989014.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            47070..48164
                     /locus_tag="VVK04_000308"
     CDS             47070..48164
                     /locus_tag="VVK04_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU3989015.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            48176..49213
                     /gene="leuB"
                     /locus_tag="VVK04_000309"
                     /pseudo
     CDS             48176..49213
                     /gene="leuB"
                     /locus_tag="VVK04_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            49210..49479
                     /locus_tag="VVK04_000310"
     CDS             49210..49479
                     /locus_tag="VVK04_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU3989016.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            49483..49842
                     /gene="leuD"
                     /locus_tag="VVK04_000311"
     CDS             49483..49842
                     /gene="leuD"
                     /locus_tag="VVK04_000311"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU3989017.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            50061..50204
                     /locus_tag="VVK04_000312"
     CDS             50061..50204
                     /locus_tag="VVK04_000312"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989018.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            50465..50626
                     /locus_tag="VVK04_000313"
     CDS             50465..50626
                     /locus_tag="VVK04_000313"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989019.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQVEYY"
     gene            50790..52721
                     /locus_tag="VVK04_000314"
     CDS             50790..52721
                     /locus_tag="VVK04_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU3989020.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYISPEEVETDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            52708..54024
                     /locus_tag="VVK04_000315"
     CDS             52708..54024
                     /locus_tag="VVK04_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU3989021.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IVVRNHLKKNLPFTGNIAYTTREFIYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            54199..55185
                     /locus_tag="VVK04_000316"
     CDS             54199..55185
                     /locus_tag="VVK04_000316"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU3989022.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            55249..55320
                     /locus_tag="VVK04_000317"
     tRNA            55249..55320
                     /locus_tag="VVK04_000317"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55282..55284,aa:Arg,seq:ccg)
     gene            55503..56201
                     /locus_tag="VVK04_000318"
     CDS             55503..56201
                     /locus_tag="VVK04_000318"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU3989023.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            56192..59731
                     /gene="smc"
                     /locus_tag="VVK04_000319"
     CDS             56192..59731
                     /gene="smc"
                     /locus_tag="VVK04_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU3989024.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQVRIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            59728..60522
                     /locus_tag="VVK04_000320"
     CDS             59728..60522
                     /locus_tag="VVK04_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU3989025.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            60522..61340
                     /locus_tag="VVK04_000321"
     CDS             60522..61340
                     /locus_tag="VVK04_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU3989026.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISLELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            61344..62633
                     /gene="ftsY"
                     /locus_tag="VVK04_000322"
     CDS             61344..62633
                     /gene="ftsY"
                     /locus_tag="VVK04_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU3989027.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDLTFTEADEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(62677..64164)
                     /locus_tag="VVK04_000323"
     CDS             complement(62677..64164)
                     /locus_tag="VVK04_000323"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU3989028.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
BASE COUNT        20170 a        11205 c        13767 g        19144 t
ORIGIN      
        1 aataatagag caactacagt agtagcttaa aaacatgatt aaatcgctat tcttaggagt
       61 agcggttttt ctttttgttt aatactcttt gaaaatctct tcaaaccacg tcagctttgc
      121 cttgccgtac tcaagtacag cctgcggctc gcttcctagt ttgctctttg attttcattg
      181 agtataaaaa gggttaagta agtatagtaa attgaaataa gatatgaaca aatcgattag
      241 aaaagtcaaa ttaatttcta gaaatatgtt agaaattggt ttgaattccg caatcaattt
      301 gttcagtttt tatttcattt aattagaatt tcccaactgt ctaactcaac taaaaatccc
      361 caatcgtagt gattgaggat taagcaaata aatcttaaac aataccttgg gcaatcatag
      421 cgtttgctac attttcaaag gcagcaatgt tagctcctgc aaggtagtct ttatcaagac
      481 cgtatgtttc tgaagtcgtt ttagctgtgt tgaagatgtt tgtcatgatg tctttgagac
      541 ggccatcaac ttcttcacga gtccatgaga ggcgaagact gttttggctc atttcaagag
      601 ctgaaacggc tacaccacca gcgttggcag cttttgcagg tccgtagaag ataccatttt
      661 ctttgtaaac tttgatggca tcaaggtcgc tcggcatgtt ggcaccttca gatacacaga
      721 taacgccttg agcaaccaaa cgtttagctg cttcaccgtt gatttcgttt tgagtggcac
      781 atggaagagc aatgtcatag tttccagcgt aagtccatac agtaccttcg tggtaggttg
      841 cagttgcttt ttcagctgca tactcagtca aacgagcacg acgtttttct ttaacatcaa
      901 ccaaaagatc gaagtcgata ccattttcat cgatgacata accatttgag tcagaaacag
      961 aaataacagt tgcaccgagt tcagttgctt tttgaagagc atattgagca acgttaccag
     1021 aacctgaaat aacgactttc ttaccagcaa agctgttacc gttagctttg agcatttctt
     1081 cagtatagta aaccaaaccg taaccagttg cttctggacg aatcaagctc ccaccaaatc
     1141 caagaggttt accagtcaag acaccagcat caaattgctt aagacgtttg tattgaccgt
     1201 aaaggtaacc aatttcacgt ccaccaacac cgatatcacc agcaggtacg tcaagtgatg
     1261 gtccgatgtg tttttgcaat tcagtcatga agctttggca gaagcgcatc acttcagcat
     1321 ctgttttacc tttaggatcg aagtctgatc cacctttacc tccaccgata ggaagtccag
     1381 tcaagacatt tttaaagatt tgttcaaatc cgaggaattt caagatccct tggtttacag
     1441 ttgggtggaa acgaagtcca cctttgtatg gtccaacagc tgagttgaat tgaacacggt
     1501 aaccacggtt tacttgaatt tttccatcac ggtcaaccca aggaacacgg aaagaaacca
     1561 cgcgctcagg ctcagtaata cgtgccaaga tattttcttc gatatactca gggtgttttt
     1621 caaatacagg ttctaaagtg ttgaaaaatt cttcaacagc ttggaggaat tcagcctcgt
     1681 gcccgttacg agctttcaca gtttcaaaca cgctttggat atattcttta gcagatgtca
     1741 tatcgttctc cttttattgt catattttat tacataagac attatagcag aatttttttt
     1801 cactgtaaag aaaaaacaga aattttctaa aaattctttc aattcagttt ttggtttttt
     1861 tgaaaataga taaaaaaaca aacgtttttc ttggaaatat ctttcttaaa gacaaaatct
     1921 taaagtatgg tatgctataa gaaaagaaaa tgtttagcaa ttcagaaatc acttgttaat
     1981 ttatccgtga tatattagat ttgccagtaa aactatgacc attttggagg aaagcaatat
     2041 ttataccaga ctaaaatcaa aaagcattat ataatagtga tatgaaatca actaaagaag
     2101 aaatccaagc catcaaaaca cttttaaaag actctcgtac agctaaatat cataaacgcc
     2161 ttcaaatcgt tctatagtaa aacgaaacaa gaacagggca aatcgatcag gacagtcaaa
     2221 tcgatttcta acaatgtttt agaagtagag gtgtactatt ctagtttcaa tctactatat
     2281 ttcgtctgat gggcaaatct tataaagaga ttatagaact tttagactgt aatcaaacaa
     2341 cgatttagcg aaatgtaaaa aatatgagga gttcggactc gactctctct ttcaagaaac
     2401 acgtggtggt cgtaaccatg catatatgac agttgaggaa gagaaagcct ttcttgcccg
     2461 tcatttgaag gctacagagg caggagaatt tgttacaatt gatgccttat ttcaggctta
     2521 taaaaaggag tgtggatgaa cgccttttta gaagagcttt cacaagctta tccttttact
     2581 cgttatggac aatgctatat ggcataaatc aagtacctta aatattccga ctaatattga
     2641 ttttaccttt attcctccat acacaccaga gatgaaccca ttgaacaagt gtggaaagag
     2701 attcgtaaac gtggatttaa gaataaagcc tttcgaactt tggaagatgt catacaagga
     2761 ctggagaagg aggtgataaa gtccatcgtt aatcggagat ggactagaat gctttttgaa
     2821 agcagatgag tataagtcct cgttttgaaa ccttagagca ggccattgcc tccaaagatt
     2881 tggaaaaagt ccgagaagct tttaagaaaa tgaattccac ttggaccatc aatgaaagtg
     2941 tggttcgtga caatagtaca gctcattatg gacgtgttga aacagctatt tccttcctgc
     3001 ctagtagcat ggaaaccgaa cctacagatg agtctggaac atgaaaacag cagttgattt
     3061 caagaaacaa aaaagaacag tcgaaactgt tcttttatca ttatttgaga ccgtattttt
     3121 tgttgaaacg atccacgcgt ccatctgctt gagtgaactt ttgacgtcca gtgtagaatg
     3181 ggtgtgagtc tgatgaaatt tccacacgga tcaatgggta agtttcgcct tcgaactcaa
     3241 ctgtttcgtt agagcgtttt gttgaaccgc taaggaattg gtaaccagta gttgtgtcca
     3301 tgaagacaac tgggcgatat tctggatgga tatctttttt cattttgcaa tatttccttt
     3361 ctgccatggt ctctttgcga gccatagatt gttaccatac tagtctatca gattctgaaa
     3421 agtttggcaa gtattttatc agtttttaag caagtttttt aacttttggt agatgatttc
     3481 gttttcttct aggctatagg aattagcacc acttgctaga gggtggcctc caccatcatg
     3541 ctccttggca atttcattga taggatggat tttactgcgt aagcgaactc ggtagtggcc
     3601 atcagcctgt tcgacaaaaa ttccccagag actcactctg tcaatgcgtc caggtgcacc
     3661 gacaatggct gcagtttcag catcggttac attgtattgt ttcaagactt cttgactcag
     3721 gataacgcga gcagcaccat tttcatccac ttccagatgg tcgtagatgt agccttgcag
     3781 tttagcaatt ttgtagctca tagtgtccat tttgcgagtg agagccgcaa agtcaaagtt
     3841 atgttctctc aaataagcag ccaggcgaag agtccgtgca gtggtagaag ggtagaggaa
     3901 gcgacctgta tcaccgacaa ttcctgcaaa gagcaactca gcatcgcgat ctgccaaggc
     3961 tagttgggtt gtttgggcaa atagggtaat catctcgcta gcgctacttg aactagtatc
     4021 gacccaagac aggtcaccgt atacatcatc atttggatgg tggtcaatct taatgagaaa
     4081 atcaccttga ctatagcgct tatcatcgat acgagcagta ttagctgtat cacagacgat
     4141 gacaagtgcg ccttggtagg ctctatcttc aacaagatcc atctcagcca tccaagtaag
     4201 agttggttca tcaaaaccga cggctttgat ggttttttct gggaaatgat gttccagcaa
     4261 ggctttcaat cccacctgac ttcccaaggc atcagggtct ggtttcatat gacgatgaat
     4321 gataatggtg tcgtattctt taattttttc taaaatttgt tggcaaatct ccataaataa
     4381 cctcaattct ttctcatttc attgtagcac aagaattttt atttttaaaa tgaaaaagat
     4441 gtgatataat ggagaaagat aaattgagga ggacgatatg gcattagcaa aaattgtatt
     4501 tgccagtatg accggtaata ccgaagaaat tgcagatatt gtagcagaca aattacgtga
     4561 cttgggcttg gatgttgatg ttgatgaatg tacaactgtt gacgcttcag acttcttgga
     4621 agcagacatc gctatcgttg cgacctatac ttatggtgat ggtgaattgc cagatgagat
     4681 gatggacttc tacgaagatc tagcagatct caacttgaat ggcaaaatct acggagtggt
     4741 cggctcagga gataccttct acgatgaatt ctgtaaggct gttgatgact ttgaccgtgt
     4801 ctttgtttca acaggagcag aaaaaggttc tgagtgtgtc aaagttgatc tttctgccga
     4861 ggaagaagat attgaacgct tggaacaatt cgcagaagaa ttggttgcta aagtaggata
     4921 agcataaaag tgcgctgatg taatcaatca gtgcattttt cttatcgaga gttgggattt
     4981 tactagccta attgatggct ttttgataca ataattcaaa taaaggagga gactgtatgg
     5041 atttagatat tattcgtcaa gaaatcgatc aaatcgacga ccaaattgtc aaactgttag
     5101 aagaacgaat gcatttagtt gagggggtgg ttgcttataa gaaagcttca ggtaaaccga
     5161 ttttagatac taagagagaa gaagttattt ttgaaaaggt tgggagtcgt gtagaggaca
     5221 agcgctatca ggagactatt gtagcgactt tttcggacat actcaaacgt tcgcgtgatt
     5281 atcaggatca aaatatcaaa tgaaaaaaga acaattttat ccgctaggaa tttttctagc
     5341 tgctatgttg ggcggacttg tccgatatct agtttccacc tggttaccag ccagtccaga
     5401 ctttccttgg ggcactctct ttgtcaacta tctgggaatt ttctgcttga tttttcttgt
     5461 caagggctat ctggtctata aggggactag taagggcttg attttagcac tggggacggg
     5521 tttttgcgga ggtttaacaa ctttttccag cctaatgctt gatactgtga agctgcttga
     5581 tacagggcgt tattttagtt tagtcctgta tttgcttttg agtatcggtg gaggcctgct
     5641 tttagcttac tatttgggga ggaagaaatg gtaatcgtct atcttgcaat cgcctgtggc
     5701 ttgggagcac tcgtacggta tttcttttct cgctataatc aagcttctaa attgccactc
     5761 ggaacgctca tagctaatct tttaggttgt tttttaattg gagtattcta caatcatgta
     5821 gagtctaagg aagtatatgc tattctagca acaggatttt gtggcggttt aacaactttt
     5881 tcgaccttga atgacgaact tcaaagactg ctaagtgata agaaggtctt ttattcttac
     5941 ctgactttga cttacatagg tggtttggtt gcgatttttt taggaatttt gctataaatt
     6001 tctttacttt tttttagaaa tttggtaaac tatatcttgt gtgtaatgga cgcacaaaaa
     6061 tacagtttat ccgctgagga agattcctca agattgacaa agataggaga ataaaatgaa
     6121 tccattaatc caaagcttga ctgaaggtca acttcgtaca gatatcccat cattccgtcc
     6181 tggtgacact gttcgtgtac atgcgaaagt tgtcgaaggt aaccgtgaac gtatccagat
     6241 ttttgaaggt gttgttattg cacgtaaagg tgctggcatc tctgaaaact acacagttcg
     6301 taaaatctct aacggtgtag gtgttgagcg tatcttccca atccacactc cacgtgttga
     6361 aaaaatcgaa gttgtacgtt acggtaaagt acgtcgtgcg aaattgtact acttgcgtgc
     6421 tcttcaaggt aaggcagctc gtatcaaaga aatccgtcgt taattcgact aaaaaactct
     6481 gctttttcag cagagttttt atctagctcc cttagttcaa tggatataac aactccctcc
     6541 taaggagtag ttgcaggttc gattcctgca gggggcatgt aattagatat caaaaaccgc
     6601 tcaactgagc ggttttagtc tattctttcc ttttacagta cccatgttcg gatggcgtgg
     6661 gcaacgccgg attcgtcatt tgttttagtg atgtatttgg cgattttttt gatttctgga
     6721 tttccatttt ccatgacaac ggggtttcca acgacttcca gcatggcacg gtcattttct
     6781 tcgtctccga tagccatggt ttcatctttg gttaatccta gtttttcagc taagtgagta
     6841 atagctgaac ccttgtctac attcttttta aggagttcga ggtagaaagg agcagatttg
     6901 ttgatggagt agcgttcgta aaattctgct ggtatctttt caatcgcagc atcgagaatc
     6961 tctggttcat caataaacat acatttgacg atttccttgc cagccatttc ttcaggagtg
     7021 cggtagaaga taggcatgct gacgagggtt gattcgtgca cagtgtattt tccgatattg
     7081 cgattggcgg tatagatacc gtccttggta atagcgtgca tgtgaacact aagcttgcga
     7141 ctgagaaatt ccatatccag ataatcctca taggtcaagg attcgctgat aatctcatgg
     7201 ccagtatcag tctcttggac aagggcacca ttgaaggtca ccacatagtc accttggtct
     7261 ctcaactgca agtcgtccag aagtttggca acacctgcga tggggcggcc agttgcaatg
     7321 acaactttga caccagcttc tttggcgtct tggatggcag aaaagacttc aggtgtgatt
     7381 tctttctgac tgttgacaag ggttccgtcg atatcaacgg caattagttt aatactcata
     7441 aatttcctct tctagttttt atttggggta aaatgatcgt tctcaatcaa gtataaaaat
     7501 tgctgggtaa tgctagcaaa gatgctgttt tggtctaaca tttctttcgg gaaataaaag
     7561 cgattatctc cgtggcgact tccagcaagg gattggacga taggggacag gctagagagt
     7621 tcggccagtt ctccattctt ttgtaaaatc tcaatctgtg tccgtggatt ttcagattcg
     7681 ggacgataga tatcataagg gaggtcaaag ttcttatgaa tggcagtata gtagtcggga
     7741 tcaaagccaa tgtcctcaac caattttctc atgctagcga gttggtcttg atcttcttgt
     7801 gaaaaggtaa tggatttaaa gaccttgcgg ttgacaaagc gttgcgataa atctgcgaga
     7861 attttgtcag gactggtcat ccagagctgg aagtaggtat tcatcacacc atcatctaga
     7921 gccagatagt cagtcaaggt cacatttttt tcgaagaaag gcaggaggtg tagagaagtt
     7981 cgggcaaaga aatccttgtc ctcaggatag agttccttgg cgcgtttgag aagattctgt
     8041 aggagaactt ccatggcgcg tgttgcgggg tggaaataaa cctgcatgta catctggtag
     8101 cgactgagga cgtagtcttc gatggcgtgc atgccattgc gctgaaaggc gataccattt
     8161 tcgataggac gaatgactcg gaggattcga gtcaggtcaa attccccata ggatgctcct
     8221 gtaaaatagg agtcgcgcaa gagatagtcc atgcgatctg cgtcaatctg actagaaatg
     8281 agctgcacga cctgcttatt aggataggta tggtcaatga cactggccac cttttctggg
     8341 aaatcaggtg ccacttgtag caggacttgg tgaatctctg tctcaggatt ttgaataatc
     8401 tcctgagtaa tggcttcatg gtctgtatca aagagatttt caaaagtatg ggagtaggca
     8461 ccatgcccaa ggtcgtgtag gagagcagcg gtcatggtca agagagactc ggcaggattc
     8521 cattcctcag gatatttttc ttcgaaaatc tctgtgatgc gtcgtgcaat ttcatagact
     8581 cctagacagt gagagaagcg actgtgttct ccaccgtgga aggtataact ggaagttccc
     8641 agttgtttga tccggcgcaa acgctgaaat tcttttgtat taatcaagtc atagatgatt
     8701 tgattattga catggatgta gttgtgaact gggtcacgga atactttttc gttcatatga
     8761 ccattatagc aaaatcctgc tctttttggt aaaatagtag gacaagagac aagaaagagg
     8821 acctgatgtg aagattcgga tgcgaaatac aattcagttt gatgagcagt tggaagtgat
     8881 tgaccagctt tatgatgtgg aagtgcatga aaaaggagat tatagctacc tgcttttcta
     8941 taatgaggaa aaggaaaaag tagtgattaa atttcatggt caagaacttg tgatgagccg
     9001 attttctaat cccaagacca ttatgcgctt tctaaaggat agcgatagtt tagcctatat
     9061 tcctacacct atgggcatgc aggagtttac catccaaacg agccattatc aagttgatag
     9121 gcaaaagatt gaactagatt atcaactaca aaatcaagag ggacatccct ttgccagcta
     9181 tcaattggaa attacttggg gctaggctca tgtctttttc aaatttagct atctatcttc
     9241 ttggattggc tccctagtgt ggtagattgg ggataatatc caaatttcat acagcagtta
     9301 tattgttatg tacacagaga ttagttttgt actagtctct ttttctttat tttaccgaag
     9361 actattggtt ggataatcct ctcaaatatg gtatactcat tactgtaaaa ggagatggat
     9421 gcctagatgc tgaaaacaca agaaattgcc gataaatatg gtataacaag acagacattg
     9481 aataattgga tgcaaaaagg aataatttct caacctcgaa aaaataatcg ttctgcttat
     9541 gaatgggaag aagaaaatga aaaagagatt gtgagagtga tttcagaaga aattcctgca
     9601 aaatattatg tttcaaataa agagacatta aaaattggaa atcgacgcta tctaggaagt
     9661 aaacaaaaga tgcttgattt catattgaag acagtatcag aaaatattgg aagtatcgat
     9721 agtgtggcgg atatatttgg tggaacaggt gttgttgcag acttatttag aaaacagaat
     9781 aaaaaagtta tagtgaatga tatactctat agcaactttg tttcctttca aacttggttt
     9841 tcgaatgagg atgtagatat tcataaagtt tctcatataa ttgatgaatt aaataattta
     9901 tcccctaaaa aaggctatgt ttctaagaat tttggtggtg cttacttttc tgaagaaaat
     9961 gctggaaaga ttgactcaat tcgtgaagaa attgaaaaat ataaatcagg taatcagaga
    10021 gagtatttca tgttactaac cagtctattg tacgctatgg ataaagtggc taatactgta
    10081 ggtcattatg acgcttatag gaaaaaaatg gattattgca aggaaatata tttaagagtc
    10141 cctgagtata atgaaaacaa tcagaatgaa atttataata aagatgccaa taaattagtt
    10201 aaagaaattt atgcagatct tgtttatatt gatactccat ataattcccg tggctatgaa
    10261 aatgcctacc atgttttaga aaatattgct gaatggaaaa aaccagatgt agaaggtgta
    10321 gcgaaaaaag cagttaatcg ttcagaaaaa gggtcggatt atacaaaaag taaagctcct
    10381 caagcttttg aagatttaat tctaaacatt aatgctaagt atatattggt tagctataac
    10441 aatatgaata aaaaaggtaa ttcccgttca aatgctaaga tttcaaacga agaaataatt
    10501 aagattttat caaaacgagg taaggttcaa gtatttgaaa ctgatttctc acctttcaca
    10561 actggtaagt ctaaaattga aaaccacaag gaattgctat atttatgcat aatttctcca
    10621 gagaaaaaaa aagaaaaaaa gttaattaag agcgctctta actatactgg aggaaagtat
    10681 aaattactcc ctcagttatt acctcttttt cctgaaagct acaataattt tattgattta
    10741 ttctctggtg gagcaacggt ggcagttaat cttgctaata ttaataaatc aaaaacgaaa
    10801 aagtatatca tcaatgatat aagtgaggaa gtaattgatt tttataaata tttggaaagt
    10861 caaaaagatg taacggtatt tttggataaa gtagagaaag ctatagaatt ttataaactt
    10921 tcgaacacac agaaatatag ctatgctcac tacggtgtaa acagctctac aggactgggg
    10981 tcttataata aagaagcttt tctaaaactt cgtcaagact acaataagaa aaattataat
    11041 aaatttgata aggaagtgtt attttatcta ttaattgtat ttggttttaa caatcaaata
    11101 agatttaata ataaaggaga gtacaatctt cctgtaggta agcgtgattt taacgctaat
    11161 atgaaatcta aactaattac gttcattcaa ggtttacaaa attacaattt tgttatccaa
    11221 tcttgtgatt ttcgtaaaac tatgaatcaa gtaaataaag gagattttgt atatacagat
    11281 cctccttatc gcattactac tgccgcttac aatgaaaatg gtgcgtggac attaaaggat
    11341 gatttggatt tgtttaagta tttagatagc ataaacgata agggagctta ttttgctctt
    11401 tctaatgttg tcattcataa caataaagaa aataaagaat tgatgaaatg ggcttcaaag
    11461 tataatttac atgtattaga ttaccattac aataatagta attatcagtc taaggcgaaa
    11521 atgagtaata ctgttgaagt cttgattaca aactataatt cgaaaggtga tatatgaggc
    11581 taaaagagtc aacaagcatt tttaatatgg gtgatacgag tattcgtgtt aaagaagttg
    11641 tccctatcta caaacagatt ttaaaaactc ttcaaaagca taatcagtca aatcagaaat
    11701 ggaacaatga gagtcaagca agtttttatt catcagtttt aagcgatttt gcaaaagctg
    11761 aaacagagga tggaattaac ctttttggga atttgaatag aaatgaaata actggtttag
    11821 acaaaagagg gagaacttta acaaatgctc ttgtcaagat tggttttatt aactatgata
    11881 gaaaattatc tcaagttggg ctgaattata tttctgaaac agagcaagct tttgataaat
    11941 tagaagaact ttttggttta acaattgata atcttgttta ttttaggcaa ttattgaagc
    12001 ttcgtatata tgatagtaac tctgataaat acttctataa tttccgtttt gctcttgctt
    12061 ttttgaacag atatagcaaa gttcctgtta gagattttct atggatagtg gaaagcatta
    12121 agccaaattt ttcagaagaa aaaatcaaag tgattatcga taattaccaa tctgtttatg
    12181 ataacaataa aacttttgaa cagtatagag atgaagagtt cgctaatcat atattgattc
    12241 ctgaaagagt ggatgaagct cgcaaaatgt ttagtattaa aaatttttcg gatgaaaact
    12301 tcaaaaaact ttttccaaat cgaaagaata gtaataaaag tttagaatat aaaagttttg
    12361 ttctttcaat tataaacttt acagaagaaa agacagagcg gtcatttgaa gaaatgatga
    12421 gtctttctaa acaagatgct attaagaaag cttttggaga tggtaaggct gttttcaagt
    12481 ataaaaataa agattctatt caagatttta taactaaaaa cagtgataat ccattgctat
    12541 caggtcaata tttggatata tattatgcat ttacatggtc taagcataat gatttgatta
    12601 aagaatacag tgatatgtgt aaaagaatat tttctttgtc tggagtaatc agttttaatc
    12661 aaggaattgt atcgcttggt cgaccttgga tttttcctaa acttttctct ttattaaatg
    12721 gtaattttaa gatttctggg gaagcaagct atgaagagta tgagaacgat ataaagagtt
    12781 ctttttatca agatatctgt atatcggata ttttagaatt atcttatacg caagttttag
    12841 aaatacaaaa tcagattgcc gaagaattcg gcattgctga tatttcaaat attaaacaat
    12901 ttgtagcaga caaacaggaa agagagttta gggaatttgt tgaacaagaa tttggtatca
    12961 ctaaagtatc tgaagttttg agttttattt ctcaaagaaa tgataagaaa gttcaagaac
    13021 ttgttacgga taatgcctta gttcctacta ttttcgaata tatattggcc attgcatggt
    13081 attatatatc agataagaag tttcaactta gaaaatccat gcagttgaca ttttctgctg
    13141 ataacctccc actatcacat gctggaggca ataaaggaga tatcgagatt gaatatagcg
    13201 ataaaatgct tttacttgaa gcgacattaa tggataaatc aactcaaaaa cgtggtgaat
    13261 tagagccagt tatacgtcat tctgtaaatt tagcattatc tactaataaa ccgttacaaa
    13321 caatatttgt agctaatgaa gtagatgata atgtggttaa tatttttagg gctacatcgt
    13381 ttattcagct aaatggaaca ttaacgaaag gtagcgtaaa agggctaaat atctttgctt
    13441 tgacaattcc agaaattata aatattttgg atagaaagat taacgagcag agaattttcg
    13501 aaaaattaga tgatttttct actatcgaac cttataggat agaaaatgga tggcgtgaag
    13561 agatagtatc tgaaatttta gcatagcctg taggaaatgc gagtaattat agaggtttgt
    13621 ataagacaat tgatgtagaa aggtttgtat tcaatgattc aaagaggttc agagtttaga
    13681 aaatgggatt tacatattca ttctccctat acagtgttaa ataatcagtt tgataagctg
    13741 cctgatggaa gtccagatgt agaaaaattc attcaaaaga taaaggacga aggtatttct
    13801 gctgttggat tgaccaatta tttcagattt agtgatgatg actttaagtt aaaagatagg
    13861 ttaaatgaag aaggaattgc aactttttta aatcttgagg ttagattatc aaacattaat
    13921 aaatcagatg aactttttga ctatcatgta gtatttggaa atgaagttca agatgatata
    13981 gtaaaaaatt tacttggtca tttaaaggct aatattggtg atgatgaaaa atcatttaat
    14041 cgtttaagta aaactgagat agaagataag gctcatattc cttttaaaga tttattaaaa
    14101 gtcttaaata gcgatagaga acttaatggt cgttttctaa ctggctttct ttcgagaggt
    14161 cacggtagtg caactagtga ttctgattct aaaaataagg cagtttatga agatatttgt
    14221 atcaattctg attttttgat tcattctagt aatgaagtaa atatcacaaa agatagagaa
    14281 ttttggcttg ataaatcccc gcatataaga ccactacttc aatcctcaga ttctcactct
    14341 ttggagcaaa taggaagtaa atattcttgg gtaaaagcag atttaacttt tgatggtcta
    14401 gaacaaataa agtatgaacc agaatatcgc attagtgttg agaaagaaaa accaactctc
    14461 aaaaaggatg aacttgtcat tgataagatt ctatataacg gtcaagatat ttatctatcc
    14521 gaaaatctaa atacaattat tggtggtcgc tcaactggta aatcaactct actaaattct
    14581 atagctaaaa agctgggacg agagctgaat ggtgattcat attattttga aaatatggat
    14641 gattttcaaa ttatttggaa agaccagcaa gaagataatt ccagacagat agagtatata
    14701 cctcaagagt atatgtttgc tttagccaga gacaataaga agcttaaaga tttggtagga
    14761 agtattattc aatccaaaga aatgaactct gaattaaaga aatatgagca aaattgcgct
    14821 actctacatc ttgaaattag agggttactt gatagttata aagagaacca aaaaaacatt
    14881 catgagctaa ttaagccaga agcagaaaaa caagctactc aaaatcgaat aaaaacatac
    14941 gaaactaaga aaaaagaatt attaaatgct agtgagataa cggagcaaga aagagattta
    15001 tttgaaaata aaaacaaaga attgcagtta ttgaaaacac aaaaagagat tcatgaatct
    15061 gacttgcgat atgtatcaag cattcttcca attacatttg aggttgaaag tttgcccaca
    15121 acgactactc cgtctcaaga tttaagggtt aaaattggtc agattacagc tcggttgcgt
    15181 gattccgtca gagcacaaca ggaacatgaa attaggataa ttaagttaga aaaagaaagt
    15241 ctaatcaaag ctattgaaaa taaaatttcg gacataggaa atgatgacat atacaagaaa
    15301 tgtgttgagg caatgaaaaa taattcagag atagcgagat taaattcttt aattaagaat
    15361 gaagttgata ttttagctaa aattgaagcg tttgaaaaac aaagggatga attcgataaa
    15421 gtaacagaag aaattcaaaa agagattatt tcgaaatata aggaatactc taatattaga
    15481 actgaattat tgaataattt caagattgaa gatgataatg gagataatct aaagatttca
    15541 gtcaagttct cattaattga tttggaggct gaatttgatt atattaatgc tcgaggtcgt
    15601 tcgaaacaag attttataga aaaaatgata ggttcttttg aagaagttgt tgattcaata
    15661 tttgacgagg atagtcttgc gtttaatgga aatagggata aattcagtca cattgagcat
    15721 ttcttcacta ctaattttta cgaatatagt tttgagattg aatatcaagg tgataaattt
    15781 gaacaaatgt ctcctggtaa aaaagcgttt attgtattaa aattaatatt agagttttca
    15841 gatagtaaaa tccccgtatt aattgatcag cctgaagata gtttggataa tagggcaata
    15901 tatagtgaat tgacaaaata catcaaaaaa actaaaaaga atcgacaaat aatcatagtt
    15961 actcacaatc ctaatatagt tgtatctggt gatgcagaaa atattattgt agctaatcag
    16021 caatctgata attctccaaa tcaaaatggt aagaagtttg attatgtaaa tggtgcttta
    16081 gagaaccgta ataatgattc tacatctgaa ttcatacttc aaaaatacaa catcagggaa
    16141 catgtatgtg atattttgga aggtggagaa gacgccttta ttaagaggga aaataaatac
    16201 agtattaatg gctaataata attgtattaa ttaaaaatgg agagcattaa tttataaaag
    16261 acacatattt agttctagca aacagtcttt ttaaggagtt aggattggta attggactgc
    16321 cgggtaatgt gtggtataat aaaagttatg gaaatcgaaa aaaccaatcg tatgaatgcg
    16381 ctctttgaat tttatgcggc gcttttgaca gataagcaaa tgaattatat cgagctctac
    16441 tacgctgatg attacagcct tgctgaaatt gccgaggagt tcggtgtcag tcgtcaggct
    16501 gtctatgaca atatcaagcg aacagaaaag attctggaag attatgagat gaaattgcac
    16561 atgtactcgg actatattgt ccgcagtcag atttttgatc agattttgga gcgctatccc
    16621 aaggataact ttctgcagga gcagatagaa attttaacaa gcattgataa tagagaataa
    16681 gaggaagaaa aatggcattt gaaagtttaa cagaacgttt gcagaacgtc tttaaaagtc
    16741 tacgtaaaaa aggaaaaatc tctgaatctg atgtccaaga ggcaaccaaa gaaattcgct
    16801 tggccttgct cgaggccgac gttgccttgc ctgttgtaaa ggactttatc aagaaagttc
    16861 gtgagcgtgc agtcgggcat gaggtcattg atacacttaa tcctgcgcaa cagattatta
    16921 aaatcgttga tgaggaactg acagccgttt taggttctga tacggcagaa attatcaagt
    16981 cacctaagat tccaaccatc atcatgatgg ttggtttaca aggggctggt aaaacaacct
    17041 ttgctggtaa attggccaac aaactcaaga aagaagaaaa tgctcgtcct ttgatgattg
    17101 cggcggatat ttatcgtcca gctgccattg accagcttaa gaccttggga caacagattg
    17161 atgtgcctgt ctttgcactt ggaacagaag taccagctgt tgagattgta cgtcaaggtt
    17221 tggagcaagc ccaaactaat cataacgact atgtcttgat tgatactgcg ggtcgtttgc
    17281 agattgatga gctcctcatg aatgagcttc gtgatgtgaa agcattggct caaccaaatg
    17341 aaatcttgct tgtcgttgat gctatgattg gtcaggaagc agccaatgtt gcgcgtgagt
    17401 ttaatgctca gttggaagtg actggggtca tccttaccaa gattgatggc gatactcgtg
    17461 gtggtgctgc tctgtctgtt cgtcacatta ctggaaaacc aatcaagttc actggtacag
    17521 gtgaaaagat tacggacatt gaaaccttcc acccagaccg catgtctagc cgtatccttg
    17581 gtatggggga tatgctcact ttgattgaga aagcttctca ggaatacgat gaacaaaaag
    17641 cccttgaaat ggctgagaag atgcgcgaaa acacctttga ttttaatgat ttcatcgatc
    17701 aattagatca ggtgcaaaat atggggccga tggaagactt gctcaagatg attccaggta
    17761 tggcaaacaa tccagccctt caaaacatga aggtggatga acgccagatt gctcgtaaac
    17821 gtgccattgt gtcttcgatg acacctgaag agcgtgaaaa cccagatttg ttaaatccaa
    17881 gccgtcgccg tcgtattgct gctggttctg gaaatacatt cgtcgaagtc aataaattca
    17941 tcaaggactt taaccaggct aaacagctca tgcagggtgt tatgtctggg gatatgaata
    18001 aaatgatgaa gcaaatgggg attaatccaa ataaccttcc taaaaatatg ccaaatatgg
    18061 gaggaatgga tatgtctgcc cttgaaggaa tgatgggaca aggcggtatg tctgacttat
    18121 cagctctcgg aggagcagga atgccagata tgagccagat gtttggtggc ggtttgaaag
    18181 gtaaaattgg tgaatttgct atgaaacagt ccatgaaacg tatggctaac aaaatgaaga
    18241 aagcgaagaa gaaacgcaag taagacaaga gattgatgca aatctcattt gatgagaaaa
    18301 taaagtaaaa atttctatga taaaacgtac agtatcaagg ttttagaata tctgatatta
    18361 tacgtttttt gattttaata actttgttaa gacactttta ttatggtata cgaaaaatcc
    18421 actcagctgt ctgagtggat taggtgtatt tagactctta gtctttattt tcgtatggca
    18481 agatcaagtt caagatgatt cctgtcatgg ctgaaagggc agtacctgaa agtgtaactg
    18541 gaccaagttt aaggatagct cctccaagtc caagaaccaa catagcactt gcgatgatga
    18601 ggtttcgcat ttgagcgaaa tcaacacgtt ctttaatcaa gactttcaaa ccattgctgg
    18661 cgataacccc atagagaagg attgacatac caccaagtac agcgtttgga atagttgaaa
    18721 tcaaggcagt gaatttacca aggaagctga gggcaatcgc gatgaaggca gcgttacgga
    18781 taactgagac agaagcgata cgagtcatac cgataacccc tgtattttct ccgtaagttg
    18841 tattggctgg tccaccaagg aaggcggaaa cagaagttgc gataccgtca ccaataagag
    18901 tacggtgaag acctggttct tttaagaatt gacggccaca gatttgaccc aaaacagtat
    18961 ggtctccgat atgttcagaa attgttacga tagcgattgg caagatagcg atggcttctg
    19021 gaccaaagta aagattgtac tctttaaagg caccacctgt gctaaatggc aagtagaaac
    19081 caggaatttc gaaccagttg gctttaagaa ctggtgtaaa gtcaaccaag ccaagagtta
    19141 gtgcgaaaag gtaaccaccg ataatggcaa agaggaatgg aatgattcgt aggaagcctt
    19201 ttccttttgt attgataaag gcagcaatta ggaaagtaac aacggctacc agagcatttt
    19261 tccaatttcc gtctgctaca agacctgcat tggtaacagc tgaacctgca agtccaagac
    19321 cgataacgat gatcatagga ccgataatga ttggtggcaa gagtttatca atccattttg
    19381 ttcctacaaa tcggatgctg gtagcaacaa ggacatagac caaaccagtc aagataaccc
    19441 ctgtttgagc agcagataca tcccccccca tttctttcat agccagtgac atagctgtga
    19501 taaaggcaaa tgaagaacct agataaactg gaactttaaa accagtagca atcatgtaga
    19561 tgagtgttcc aacacctgaa gcaaaaaggg caacagatac aggcattccc aaaatcaatg
    19621 gtaccaagat ggtcgcacca aacatggcga aaacgtgttg gaagctaagg agaattcctt
    19681 ttccatccga aggacgttgg tcaacgtcta gtaacaaatc aacagttgat tcttgtttca
    19741 tataaacctc acttttgggc atcagaaaag agcccattat tttacagcaa taggccctca
    19801 gagtaagact tctctaaaat ctagacttta aagagtttca aatatttttg cgtcttcgtc
    19861 acctcacggg atgacattaa aaacctttgc ttaggatagt atagcagaaa aaaatgattt
    19921 tgtaaatcat tttttcccga gcctagaaat aaaagagcga ggctgatttt gtaaatcatt
    19981 ttttcccgag cctagaaata aaagagcgag gctgattttg taaacatttg tttactaaaa
    20041 aatttaaagt gggcgtttat ttggcatacc agccttacgt ggatatttat ttggtgtttc
    20101 ttttttcttt tctaccactg tgatatagcg cggatctcta ttcggtaggg cgtagctgag
    20161 attgtcttcg accttactaa aaaggagatt gagggcattc ttagcttcta ataattcctc
    20221 aggcgcattg ctggccttga gtgccaatag tttgccacca accttaaggt agggaatagt
    20281 caattcagat aggacctgca tacgggcaac cgcacgagct gttacaaaat catattgagc
    20341 acggaagttc ttgtcttggg caaaatcttc ggcacgtccg tggtagaaat gaactccgtt
    20401 caaatccagt tcttgagcca agagttgtag gaagttgatg cgcttattga gtgaatcaat
    20461 aatggtcaca tctaactccg gatagagaat tttcattggt agactaggaa atcctgcccc
    20521 agccccgata tcaagaagtt tgatagtttc attgggaatc aaaccttgaa gaatgggtgc
    20581 aatcgaatcg taaaaatgtt tgagataaac ttcttccttg tccgtaatcg ccgtcaaatt
    20641 aatcttctca ttccactcga ccaagagctc aaaataacgt tcaaattgtt ctttttgctg
    20701 gttcgaaagt ggaagattct gctcggcaag caagttgtaa aatgtttctg gtttcatagt
    20761 tatttccttc tttagtatca tcttatttta ccacaatcat agaaaatttg atatactggt
    20821 actaatctaa aagcagaaag gacttatatt atgacttgga ttattcttgg agttatcgct
    20881 cttattgtta tttttgtgat tgttagctat aacggtttgg ttaaaaatcg tatgcaaacc
    20941 aaggaggctt ggagtcagat tgatgttcag ttgaaacgtc gaaatgacct cttgccgaac
    21001 ttgattgaga ctgtaaaagg ttatgccaaa tatgaaggtt ctacccttga aaaggtggca
    21061 gaactacgta accaagtggc ggcagcgact tcaccagcag aagctatgaa agccagtgat
    21121 gccctcactc gtcaggtttc aggtattttt gcagttgcag aaagctatcc agatttgaaa
    21181 gctagtgcta actttgttaa attgcaagag gagttgacaa acacagaaaa taaaatttct
    21241 tactctcgtc aactctataa cagtgttgtc agcaactaca atgtaaaatt agaaactttc
    21301 ccgagcaata ttatcgctgg aatgtttgga tttaaagcgg cagatttcct tcaaacacct
    21361 gaagaggaaa agtcggttcc taaagttgat tttagcggtt taggtgacta agatgttgtt
    21421 tgatcaaatt gcaagcaata aacgaaaaac ctggattttg ttgctggtat ttttcctact
    21481 cttagctctt gttggttatg cggttggtta tctctttata agatctggac ttggtggttt
    21541 ggttatcgca ctgattatcg gctttatcta cgctttgtct atgatttttc aatcgacaga
    21601 gattgtcatg tccatgaatg gagcgcgtga ggtggatgag caaacggcac cagacctcta
    21661 ccatgtagtg gaagatatgg ctctggtcgc tcagattcct atgccccgtg ttttcatcat
    21721 tgatgatcca gccttaaatg cctttgcgac aggttctaat cctcaaaatg cggctgttgc
    21781 tgcgacttca ggtctactag ctatcatgaa tcgtgaagaa ctagaagctg ttatgggaca
    21841 tgaagtcagt catattcgta attatgatat ccgtatttcg actattgcag ttgcccttgc
    21901 tagtgctatc accatgcttt ctggtatggc aggtcgtatg atgtggtggg gtggagcagg
    21961 tcgcagacga agtgatgatg accgagatgg aaatggtctt gaaatcatta tgctagtggt
    22021 ttccctacta gctattgtac tggcacctct cgctgcaacc ttggttcagc tcgctatttc
    22081 tcgtcagagg gaatttctgg cagatgcatc tagtgttgag ctgactcgca atccccaggg
    22141 aatgattaat gccctagata agttggacaa tagcaaaccg atgagtcgcc acgtcgatga
    22201 tgctagcagt gctctttata tcaatgatcc caagaaaggt ggggggttcc aaaaactctt
    22261 ttatacccac ccacctatct cagaacggat tgaacgttta aaacagatgt aaaagaatcc
    22321 agaggtcgtc tctggatttt tgctatgttg caaatttata aatcttctaa attaactaac
    22381 tccaaaccgt gttctgtcat gcgatagatg atcgagcaga cttcttttaa gaaacgacgg
    22441 tcatgcgaaa cagtgatgag accgcctgga taggttgcaa agagttttct gatttggggt
    22501 tgagaagtgg gagaaaagtt tcgtgtgggt tcatccagca ggagaaagtt tggtttgcgc
    22561 aggactagat ccaaaagcag gagttttccc tgttgtccgc cagataagga gcgaatttga
    22621 tgctgcattt ctggataact gaaattgaga ctggctaggt gagagtggat tttctgaagt
    22681 tcctcttttt ccccagtttt gctgatataa gctattggtg ataaatccaa ttgtagtttt
    22741 ttgtggtaat cttgtggcat aaaaccaagg gaaatctctc ttttatcatt cagaagttgc
    22801 tttaatttgg ctaacagagt tgatttccca acaccatttg gcccgataat accgattttt
    22861 tcttgcccac ggacagttag ttgtagtttt tgaaccaaaa ctcggtcgtc aatggacaaa
    22921 ttttcttttt ccagttggac taagacttta gaagctggta atggttggat gtctgaaaag
    22981 aaaagttgga tttgttcctc ttcaagtggt ttttgagtca tggactgagc tgccttttcg
    23041 tagcgttttt cttgtgagag gacagttttc atctttttag ccaataggcg accggcagta
    23101 ctatctttgg tagctcgaag cgcagtttct acattttgct taactctccg atgtttttcc
    23161 atggttttat cgtaggctct ttggttgtta gcagcttgct gactttgttt ggcaaaatta
    23221 gcctttctct gctcactata gctatcatag tctaaatgct ctactagcgt ttccgcttct
    23281 ttacggtgtt tgaccagtcg caagtgaaca atagtgtctg ccgtttcaga aagaaagtct
    23341 tcatcatggg aaatgaaaat aacggtttgc ctggtctttt gaatctggcc ttttagccaa
    23401 tcaactgtct caaggtctag gtcatttgaa ggttcatcta aaaatagaat ctcaaagggt
    23461 ttggctaact catggataag ctgaattttc aaagcttctc cccctgatag attgccaatc
    23521 tcttggtcac ttgcgaaacg attgctatca aaatgcaatt cctccgccaa acgatagagg
    23581 atactgtagt ctaaatcaat agaatctaaa aagaagtagt cgtgtaaagt tttctttttc
    23641 agctcctcgg gaagtttttg aggaatgtag gccagtgact gatagtcaga ttggatgttt
    23701 cccttgatag tgaaatcaga caaagcttcc cccattaaaa ttttaagtaa ggttgatttg
    23761 ccatttcctt cttcaccaat aatagcaacc ttttccccgt cttggatggt catggttagg
    23821 tcagatacaa gatctcgtaa atctttgttt tgtgtgatgg ttagatgatt gatttttatc
    23881 atatgatttc cctttctaga atgttcatag tgcataacaa aaagctctac tttacctagt
    23941 agagcccaaa gtctatgtca aaaaaactct attaacatgc cagaaaaaga gcataaaaga
    24001 gcacacaaaa agagacaaaa acaagatcta ctaaataaag gttctttatt tgatagactt
    24061 agttgttcat gtctccctta cctccgagta ttagtatctt tatactatac ctttaaggaa
    24121 attttgtcaa cagaaaactg gaaattctat gctctaaaat ccaaaaacag gtccatagag
    24181 acttagtacg tgtttgacat gctcgtaatg gattttatca tagtttcgcc aagcagtgcg
    24241 tgcttgattg tttagtttta ggctacccag tccaatcaga ggactggtgg gttggtaaaa
    24301 tttctcaaga tcaattaaga tactgttgtt caactgttcc gtttttttga gctcttgcat
    24361 agtagtgttt agcagctctt gtagtcgaat atcatctgcc gtaccctgtt tacagttttg
    24421 gtagctttta tttaacttgg ataggagttg aatgagtttc ttgtcttcca tgtgagcatc
    24481 ctccttgatc tgatgtactc tttccctata gtatagcact aaaaaacaaa actgtcatag
    24541 taaacatgtt aaaatttcga attttaatta caaagtttgg tgtgctgatt tgtagccttt
    24601 tcatggtata atcaagagag taaatcttta tggaggaagt atgaaattaa atattcaaga
    24661 aattcgtaag cagtctgaag gtttgagctt tgaacaaacg ttagatttag ttgatgacct
    24721 gcgtgcacgt aatcaagaaa ttttagatgt aaaagatatc cttgcaattg ggaaagtaca
    24781 atatgaagac cgtatgtatt tcttagatta tcaactatct tataccattg ttcttgcttc
    24841 gagtcgcagt atggagccag ttgagttagt tgaatcttat ccagtcacgg aagttttcat
    24901 ggaaggcgca actaaccagc tagatcaaga agttttagat gatgacttgg tcttgcccat
    24961 cgaaaatggg gagcttgacc ttgctgagag tgtatcagac aatatcctgc taaacattcc
    25021 tatcaaggtc ttgacggctg aagaagaagc tggtcaagga tttatctcag gaaatgactg
    25081 gcaaatcatg acagaggaag aataccaagc tcaaaaagca gtaaagaaag aagaaaacag
    25141 tccttttgct ggcttacaag gactatttga cggagatgaa taatggtctt gtcaaaaaaa
    25201 cgagcacgaa aggtgctaga agaaatcatt gccctcttcc cagatgccaa gcctagtctt
    25261 gattttacca atcattttga actcctggtt gcggtcatgt tatcagccca gacgacagat
    25321 gcagcggtaa ataaggccac accaggtctc tttgttgcct ttccaacacc ccaagctatg
    25381 tctgtagcga cagagagtga gattgcttca catatttctc gcttgggatt gtatcggaat
    25441 aaagctaaat tccttaaaaa atgtgcccaa cagttactag acgattttga tggtcaagtc
    25501 cctcagacac gtgaagaatt ggagagtttg gcaggtgttg gtcgcaagac agccaatgtt
    25561 gtcatgagtg taggatttgg gattccagcc tttgcagtgg atactcatgt ggagcgtatt
    25621 tgcaaacacc acgatattgt caaaaaatca gcgacgccac ttgaggtgga aaagcgggtc
    25681 atggatatct tgccgcctga gcagtggtta gctgcccatc aggccatgat ttattttgga
    25741 agagccattt gccatccaaa aaatccagag tgtgaccagt acccacaatt atatgatttt
    25801 agcaatttgt aagatgctac attgaaactt tttgcttgat tttaagcatg ctttgtgcta
    25861 tagtaaatga taactaaata ttcctttaaa cctgtcccgt gaggcaggca aggagcgcga
    25921 taaagtagaa gggtgaagtc tatactgtgt gcagtagggc tcgcttggct ataaatttca
    25981 agtctccttg tttaaggaga cttttctttt tggaggtttg tcatgaaaac aaaagaagtt
    26041 gtagacgaat tgaccgtcaa acgagcgatt acgcgtatta cttatgagat tatcgaacgc
    26101 aacaaagatt tgaataagat cgtcttggct ggtattaaaa ctcgtggtgt ctttattgcc
    26161 caccgaatcc aagaacgttt gaagcagtta gaaaatcttt cagttcctgt tgtggaattg
    26221 gatactaaac ctttccgtga tgatgttaaa agtggagaag atacttcttt ggtttctgtc
    26281 gatgtgacag accgcgaagt tatcttggtg gatgatgtgc tctatacagg tcgtaccatc
    26341 cgtgctgcta ttgataatat tgtcggtcat ggtcgtcctg cgcgtgtgag tttagcagtt
    26401 ctagtcgatc gtggacatag agaattgcca atccgtccag attacgttgg aaaaaatatc
    26461 ccaaccagtc gttctgaaga aatcatcgta gagatgacag aacttgatga ccaagacaga
    26521 gttctgatta ctgaagaagc ttagaaagtt aaaggagtag ccatgtcaga aaatcaacaa
    26581 gcattgaacc atgtggtgtc catggaagac ctcactgtcg atcaagtaat gaaattgatc
    26641 aagcgaggaa ttgagtttaa aaatggagcc cagcttccct atgaagacca tccgattgtt
    26701 tccaatctct tctttgagga ttctacacgg acacataagt cctttgaagt cgcagagatt
    26761 aaacttggat tggaacgact tgactttgat gtgaagacta gttcggttaa taagggtgag
    26821 acactttatg acaccatttt gactctgtct gctttaggag tggatgtctg tgtgattcgc
    26881 catccagagg tcgactacta tagagaattg attgctagtc caacgattac gacttccatc
    26941 atcaatggtg gagatggttc gggccaacac cctagccaga gcttgcttga tttgatgacc
    27001 atttatgagg aatttggcca ctttgagggt cttaaagttg ctattgcagg tgacttggac
    27061 cactcacgcg ttgccaaatc caatatgcag attttgaaac gcttgggagc tgaactcttt
    27121 ttcgctggac ctgaggaatg gagaagtcaa gagtttgcag actatggaaa gtttgtaacc
    27181 attgatgaaa tcattgatca ggttgatgtc atgatgtttc tccgtgtgca acacgaacgc
    27241 catgatagtg gagctgtatt ttcaaaagaa gactaccatg cccaacatgg cttgactcaa
    27301 gaacgttacg atcgtttgca agaaacagca atcctcatgc acccagctcc aatcaatcgt
    27361 gatgtagaaa tagcagacca cttggttgaa gcaccaaaat cacggattgt ccaacaaatg
    27421 accaatggtg tctttgttcg aatggcaatc ttagaatccg tactagcgag tagaaacgcc
    27481 aactaaaaca caagacgtta aaagacgcca gtgagcgtcc acgagaggtg aaaatatgac
    27541 aaaaagaatt ctagtattag aagatggcac agtttttgaa ggcaaggcct tcggagcaga
    27601 tattgatgta acaggcgaaa tcgtctttaa tacagggatg accggctacc aagaatccat
    27661 tacagaccag tcttataatg gacaaatctt gacctttact tatcctttgg taggaaatta
    27721 tggtattaat cgtgatgatt atgaatccat tattccaact tgtaagggag tcgttgtttt
    27781 tgaagaagcg cgtagagcta gcaactggcg caaccaaatg accttggatg aatttttgaa
    27841 agccaagaaa attccaggga tttcaggaat tgatacgcgt gctcttacca agattatccg
    27901 taagcatggt actatgcgtg caaccttgac ccatgttggg gacagtatgg accatgtgac
    27961 ggaccagctc caagcaacag ttttaccgac agacaatatc aaacaggttt ctactaaaac
    28021 gtcttatcca gctccaggag ttggtttgag cgtggtgcta gtggactttg gtctcaagca
    28081 ctcaatccta cgtgaacttt ctaaacgcaa ctgtaacgtg acagttgttc cttattcgac
    28141 aacggctgaa gaaattctcc atctcaatcc tgacggagtt atgttatcaa atggtccagg
    28201 taacccagaa gacgttccac aagcactcga catgattcgc ggtgtacaag gaaaaattcc
    28261 aatctttggt atttgtatgg gacaccaact ctttgcaatg gcaaacgggg ctaagaccta
    28321 taagatgaag tttggccacc gtggattcaa ccatgcggta cgtgaaatcg caacaggacg
    28381 agtagacttc accagccaga accatggtta tgcagtcagc cgcgaggatt tgccagagca
    28441 cttgattatt acccacgaag aaatcaatga caagtcagtg gaaggtgtgc gccacagata
    28501 ccaacctgct ttctctgttc aataccaccc agatgcagct cctgggccac acgacgctag
    28561 ctacctattt gacgagttta tcgagatgat ggaagttttt aaacaatcaa actaagaacg
    28621 agtaaaagct cgtcggagaa tttatgtaac tgaacacgga cggaaagctc agaatgtaga
    28681 gaaatcaact tggattgtca atccttcctt gattttctaa aattcaatcg ctttctattc
    28741 gtcctttgta tcttatttaa tgtcgccctg agaggcgacg aatagaaagg agaagggtgc
    28801 tccgtatttg ctgaactgaa tacgggctac ggacggtgct aaaaagatag ttattcctag
    28861 aactgacagt tcttcgtcat aactcctatt ttagctttgt ccgcttgacg cccttaatat
    28921 cttatatatg cctaaacgta ctgatattca aaaaattatg gtgattggtt ctggtccgat
    28981 tattattggc caggctgctg agtttgacta cgctgggacc caggcttgct tgtcgttgaa
    29041 agaggaaggt tatgaggttg ttttggttaa ctcaaatcct gcaaccatca tgacggacaa
    29101 ggaaattgct gacaaggttt acattgaacc gattacactt gagtttgtga cacgtattct
    29161 tcgtaaggaa cgtccagatg ccttgctacc aacactcggt ggtcagacag gtctcaacat
    29221 ggccatggaa ttatctaaaa atggtatcct agacgagctt ggcgttgaac ttctgggtac
    29281 caaattatct gccattgacc aagcggagga ccgtgacctc tttaaacaat tgatggaaga
    29341 gcttgaacaa cccattccag aatctgaaat tgttaacaca gtagaagaag cagttgcctt
    29401 tgcagcgaca attggctacc cagtcatcgt tcgtccagcc tttacccttg gtggtactgg
    29461 tggtggtatg tgtgccaacg agaaagaatt gcgtgaaatc actgaaaatg gtttgaaatt
    29521 gtcacctgtt acccaatgtt tgattgagcg ttcgattgcc ggtttcaagg aaattgaata
    29581 cgaagtgatg cgtgactcag ctgacaatgc cttggttgtt tgtaacatgg aaaactttga
    29641 cccagttggg attcacacag gggattccat tgtatttgcc cctgcgcaaa ccatgtcaga
    29701 ctatgaaaac caaatgcttc gtgatgcgag cttgagcatt attcgtgccc tcaagattga
    29761 aggtggatgt aatgttcagc tagctcttga tcctaacagc ttcaagtatt atgttatcga
    29821 agtaaaccct cgtgtatcac gttcgtcagc ccttgcttct aaagcgacag gatatccgat
    29881 tgctaagttg gctgccaaga ttgcagtagg tttgaccttg gatgaggtta taaacccagt
    29941 tacaggttca acctatgcca tgtttgaacc agcccttgac tacgtagttg ctaagattcc
    30001 acgtttccca tttgacaagt ttgaaaaggg tgaacgccgt ctcggtacac aaatgaaggc
    30061 gactggagaa gtcatggcaa tcggtcgtaa catcgaggaa tctcttctca aggcctgccg
    30121 ctcccttgaa attggggtgc accacaatga aatacctgaa cttgcagcag tttctgatga
    30181 tgccttgatt gaaaaggttg tcaaagccca agatgaccgt ctcttctacg tatcagaagc
    30241 aattcgtcgt ggctacacac ctgaagaaat tgcagagctt acaaaaattg atatcttcta
    30301 tcttgataaa ctcttgcata tctttgaaat tgagcaagaa ttgggtgctc atccacaaga
    30361 tctagaagtt ttgaaaacag ccaaacttaa tggtttctca gaccgtaaga ttgctgaact
    30421 ctggggaacg actgatgatc aagttcgcca acttcgcttg gaaaacaaga ttgttccagt
    30481 ttataagatg gtagatactt gtgcggcaga gttcgactct gaaacgccat atttctattc
    30541 aacctatggt tgggaaaatg aatctatcag atctgataaa gaatctgtac ttgtcctagg
    30601 ttcaggtcca atccgtatcg gtcaaggggt tgagtttgac tacgcaaccg ttcactctgt
    30661 taaggctatc caggcagctg gttatgaagc tatcatcatg aactcaaacc cagagaccgt
    30721 ttcaacagac ttctctgtat cagataagct ttactttgag ccattgacat tcgaagatgt
    30781 tatgaacgtc attgacttgg aacaaccaaa gggagttatc gttcagtttg gtggtcaaac
    30841 agccatcaac cttgcagagc cattggcaaa agcaggtgtg accatccttg gtacacaggt
    30901 tgctgaccta gaccgtgccg aagaccgtga cctcttcgag caagctctca aagaattgga
    30961 tattccacag ccaccaggac aaacggctac caatgaagaa gaagcagctc ttgcagctcg
    31021 taagattggc ttcccagttc ttgtccgccc atcttatgta cttggtggac gtgccatgga
    31081 aatcgttgaa aacgaagaag accttcgttc ttacatgcga actgctgtta aggctagtcc
    31141 agatcaccca gttcttgtcg actcttatat cgttgggcaa gagtgcgaag ttgatgccat
    31201 ttcagatggt aaagatgtac tcattcctgg tatcatggag catatcgaac gtgctggtgt
    31261 ccactcaggt gactcaatgg ctgtttaccc accacaaacc ttgtcgcaaa aggttcagga
    31321 gaccatcgca gactacacca aacgcttagc aatcggtctt cactgccttg gaatgatgaa
    31381 catccagttt gttatcaagg atgaaaaagt ctacgttatt gaggtcaatc cacgtgccag
    31441 ccgtactgtt ccattcctat ctaaggtaac caatattcct atggctcaag tagcgaccaa
    31501 gctcattctt ggtcaaagtt tatcagaact tggctaccaa aatggacttt accctgaaag
    31561 catccgtgtt catatcaagg cacctgtctt ctcctttacc aaactagcta aggtagacag
    31621 cttgctcggt cctgaaatga agtcaacagg tgaagttatg ggttctgatg ctactttgga
    31681 aaaagctctc tataaagcct ttgaagcttc ttatctacac ttgccaactt ttggtaatgt
    31741 cgtctttacc atcgctgatg atgccaaaga agaagccttg aacttggctc gtcgtttcca
    31801 aaacattggt tatggaatcc ttgcgacaga agggacagca gccttctttg ctagccatgg
    31861 cttgcaagcc caacctgttg gtaagattgg tgatgacgat aaggatatcc caagttttgt
    31921 acgcaaagga agaattcaag ctatcattaa cacagtagga acaaaacgaa ctgctgacga
    31981 agatggtgag caaattcgtc gttcagccat tgaacacggg gtgcccctct tcacagcgct
    32041 agatacagct aatgccatgc ttaaggtact tgaaagtcgt agctttgtta cagaagcgat
    32101 ttaaatagaa aaataagata tagcagactg aatttagaac agtacacagg gatactaaaa
    32161 tatttctaga aattaatttg aattttctaa ttgattcgtt cgcatcttat ttcaatctac
    32221 tatagaaaaa agtctttaaa attataaaac gcatcatatc aaggtttttc aaaaaccttg
    32281 atatgatgcg ttttattgtg ggaatatgta tttcattttc tactaaaatt atgtttttga
    32341 ataacctcta tcttagtagt ttgtataatc cccctcaatc agtttttgcg ataagcttta
    32401 atgctatgac tataccactc ttgcatttct tttgatggtg gtgttatata atcgccatac
    32461 atctgggtta aaaattggtc atattttttg ggaacaggca acatacggcc ctcaaactca
    32521 attaaaatca gttctttaaa ggtatcaact gggaagattt ctttcatccc ttccttaccg
    32581 atcccaactc ctccttcata ttgaggagtg ttggttacag catttttgac tagttgatca
    32641 attttcttgt aaaagtagcg aggattgaca aatcggagag cgtaccagct acataatcta
    32701 agaaaatctt ttagtttgct gtcaccgtga actgctcgtg attttttgat ataagctagt
    32761 tgacgaagag ccacatactt atagctcttg tcgacaatgc tcaagtctgt aaatcgatca
    32821 attgggaaga catcgatgaa aaggctggta tcatgacgct tgtacttaac atggtcttct
    32881 ataacagtag aagtgtccaa aatcgatgcg aaattatgga agtaccaaga agatgtatcg
    32941 taggaaagaa ccttgtagcg agggtgattt tcttcttcaa taatcttcag taaacgctca
    33001 taatcctcac gataaaggga aatatcaata tcatcatccc aaggaatcat acctttgtgg
    33061 cggatggctc caagcatggt tccataactg agaaaataag gaatatcatg tttcttacaa
    33121 gtctcatcaa tatagtccag cagggctagt tgaatttctt taatttcttt tttttctaaa
    33181 tattgcatcc taatcctcca atttataagc gtgaaattca tgactgtaga agcgtttttc
    33241 ttctggtggt agggtcatat aatctccata aaattgtgtc aaaatagtat caaatttttc
    33301 aggtgcagga aggcttaaat tttcaaaggg taaatcgatt gttttatcaa aggtaccact
    33361 tgggaagact tccttttcct taaattttga agggataaaa gccatatact gcccattttc
    33421 acgactatat ttttgaattt ctttctcgat tttatttgca aaataacgag gagaaaccgg
    33481 tcgaaggagt aaccaaaagg ctgttcgtat ccaatctttt aaaaggctat ccttatagac
    33541 aatattttta tgtttactga aagacagcag tttgaagctt tctagtttat aacaagtatc
    33601 aatgacctta ggatcatcaa agcgatccat agggaaaata tcgataaaga taccagactc
    33661 ataggttttt gtatttcgag tatcaataat tttagtcgta ctgtcggtta tcttgataaa
    33721 gttgttaaag tagttcttat cagtttctaa ggataggagc ttatacttgc ttttttcctt
    33781 ttgaaaaatg ttaataaatc gttggtagtc ttctctaggc atggataaat caatatcgtc
    33841 gtcccaaggg ataaagccct catgtcgaac cgccccaatc agagtaccgt agttaataat
    33901 atagttgata ttgtgctttt tacagagagt atcaatataa tccaaaattt ctaattcaat
    33961 ttgtttggca tcttcaacgg ttagttgttt cattttaaac tcctatgatt ttttaaattt
    34021 attttttaag gctaggacat ggtttaaaaa ttcatagaaa atgctatctt ttgtgaagac
    34081 aagtagacta atataagaga tagctgataa caagacaatc aaaccagtat taatcaaaaa
    34141 tggcaaatta atgaccatat ccacaggata cacgaaatta atcaggaaat aaattgctac
    34201 aaaggaaagt gaaaagagag agtatcgaac agtatagcta aagatatgtc ccaagtggat
    34261 gagttgtttt ctatggatga aaatgatata gaaaacaagt agagaagcct ctgataacat
    34321 agttgtcagt aagtagtatt cgggagccac gatatggttg aaaaagagga gactattcaa
    34381 gcccaaattg agtagcccag caaagactgt atagactgtg atacgttttt catagccatt
    34441 ggtaaagaga atttgggaac caagaatggt atctaaggcc aggataatcg tacgaaaagc
    34501 gaagagagag gtcaagatgc cgcctccgat atatttttca ctaccgtaaa gtaggatggc
    34561 atttggtcct aaaaccatga gtccaaaact cagtggaatg ataaagaagt taaagattcg
    34621 actacctcta ttaaccagag aaacataggc ttctttgtct cctttcccca gatagtaact
    34681 gagacgaggc acactcactc caattgcacc tgttacaacc ccagctataa cggtcacaat
    34741 tcgctgagct atggtatagt aactaacgtt gacatcaatc cctgttttaa cgaggaagag
    34801 gcgatctaaa aaagtgaaga gcatattggc attggcaaag actaacatgg ctgtcagagg
    34861 gagaaagagt ggtttaaaat cacttaggtg aattttaaca agtttgatgt ctcttttaat
    34921 ccaaaaataa ctaatcaggt agttaatcag cgtcgataaa ctcatcacaa gtgtatagac
    34981 aacaatatcg tgttcatttt taacaaataa gaaaatagag accagcatca ggatacggat
    35041 gaaggcagtt ttgtaaaaga gaaaactgta attttccaga gcttcattga cccattcgat
    35101 tgaaaaaatc tgggcaatga gttgaatccc cataacaagg tagacctttt tgacgattgg
    35161 attatcagta aagaagagag gataggctag gatatagaca gcagtggtca aaatcgtaca
    35221 agcgatgcac aaataaaaaa gactagaaaa ggttctgtta agatcttttt tgttatcctt
    35281 gacattactg atagccctta aaccgtagtt atagacacca taagttgcaa agggcaagaa
    35341 aaatgacaaa atagtgtcga ctgagttgaa gtaaccatag tcagttcggt ccaagacacg
    35401 cgcgacatag gttccagtta ggatgggaaa aataatattc aagacacgaa ttcccatgta
    35461 agatagagca tttaatttta tacttttcat tcaatttacc tcgtttttca ttatatcata
    35521 aagttagcta ataagaaatg aagggcagta agtcaagtaa tcactttgaa gtttcaaatc
    35581 ttaaatttta agttttcttt aaggaaagta tattattctg aaggactcta aaatttcgca
    35641 gtcatttatt agtaattgct acagaattcc tagtcattac tagaaatagg cttgtttctt
    35701 tgaataatag aactgcataa ttctcctatt ctagaagggg aggaccagta tttctttcat
    35761 gataggacta gattgtggta tataggacta gattgtggta taatagagag aataagtttt
    35821 tttagtaaga caaaggagaa aatagatgat ttatgcagga attcttgccg gtggaactgg
    35881 cacacgcatg ggaatcagta acttgccaaa acaattttta gagctaggtg atcgacctat
    35941 tttgattcat acaattgaaa aatttgtctt ggaaccaagt attgaaaaaa ttgtagttgg
    36001 tgttcatgga gactgggttt tacatgcaga agatcttgta gataaatatc ttcctcttca
    36061 taaggaacgt attatcatta caaagggtgg tgctgaccgc aatacaagta ttgagaacat
    36121 cattgaagcc attgatgctt atcgcccgct tactccagag gatatcgttg ttacccacga
    36181 ttctgttcgt ccatttatta cgcttcgcat gattcaagac agtatcaaac ttgctcaaaa
    36241 tcatgacgca gtggatacag tagtagaagc agtggatact atcgttgaaa gtaccaatgg
    36301 tcaattcatt acaggtattc caaatcgtgc tcacctctat cagggacaaa cacctcaaac
    36361 attccgttgc aaggacttca tggaccttta tggatctctt tctgatgaag agaaggaaat
    36421 cttgacagat gcatgtaaaa tctttgtgat caaaggaaaa gatgtagcct tggccaaagg
    36481 cgaatactca aatctgaaga ttacaaccgt aacagatttg aagattgcaa aaagtatgat
    36541 tgagaaagac tagtaaaatg attaatcaaa tttatcaact aactaaacct aagtttatca
    36601 atgtcaaata tcaggaagag gctattgacc aagagaatca tatccttatc cgtcccaact
    36661 acatggctgt ctgtcatgcg gatcagcgtt actaccaggg aaaacgtgat cccaagattt
    36721 tgaataaaaa gcttccaatg gcaatgattc acgagtcatg tggaaccgtc atttctgacc
    36781 cgacaggaac ctacgaggtt ggtcaaaaag ttgtcatgat tcccaatcag tctcctatgc
    36841 agagtgatga agaattctat gaaaactaca tgacagggac ccatttcttg tctagtggat
    36901 ttgatggctt tatgagagag tttgtttctc tccctaaaga tcgtgtggtg gcttatgatg
    36961 ctattgaaga tacggttgca gccattacag agtttgtcag tgtgggcatg cacgctatga
    37021 atcgtctatt gactcttgct catagcaagc gggagcggat cgccgttatt ggagatggaa
    37081 gtttagcttt tgtggttgcc aatattatca actatacttt gccagaagca gagattgtgg
    37141 ttattggtcg tcattgggaa aagttggaac tcttctcatt tgccaaagaa tgctatatta
    37201 cggataatat tcctgaagag ttggcctttg accatgcttt tgaatgttgt ggtggtgatg
    37261 gtactggacc agctattaat gacttgattc gctacattcg tcctcaggga acaattctca
    37321 tgatgggagt tagcgaatat aaagtcaatc tcaatactcg cgatgcctta gaaaagggct
    37381 tgctcttggt tgggtcatct cgttctggtc gcattgattt tgaaaatgct atccaaatga
    37441 tgaaagtcaa gagatttgcc aatcgtctta aaaatatcct ttatctagaa gaacctgtaa
    37501 gagaaattaa agatattcac cgtgtctttg caaccgattt aaacacagcc tttaaaacag
    37561 tgtttaagtg ggaagtataa gtcctggagg ttaattgtgg agaaaatcat taaagaaaaa
    37621 atttcttcct tacttagtca agaagaagaa gtcctcagtg ttgaacaact gggtggaatg
    37681 accaatcaaa actatttggc ccaaacaaca aataagcaat acattgttaa attctttggt
    37741 aaagggacag aaaagcttat caatcgacaa gatgaaaagt acaatcttga actactaaag
    37801 gatttaggct tagatgtaaa aaattatctt tttgatattg aagctggcat caaagtaaat
    37861 gagtatatcg aatctgcgat tacgcttgat tcaacgtcaa tcaagaccaa gttcgacaaa
    37921 attgctccaa tattacaaac tattcataca tctgctaagg aattaagagg agaatttgct
    37981 ccttttgaag aaatcaaaaa atacgaatcc ttgattgaag aacaaattcc ttatgccaac
    38041 tatgaatctg ttagaaatgc agtcttctcc ttagagaaaa gactggctga cttaggtgtt
    38101 gacagaaaat cttgtcatat cgatttggtg cctgaaaact ttatcgaatc acctcaagga
    38161 cgactttatt tgattgactg ggaatattca tcaatgaatg atccaatgtg ggatttggct
    38221 gccctctttt tagagtctga attcacttcc caagaggaag aaactttctt atctcactat
    38281 gagagtgacc aaacaccggt ttctcatgaa aagattgcta tttataaaat tttacaagat
    38341 actatttgga gtctatggac tgtctataag gaagagcaag gtgcagattt tggttactat
    38401 ggtgtgaatc gttaccaaag agctgttaaa ggtttggctt cttatggagg aacagatgaa
    38461 aagtaaaaac ggagttcctt ttggccttct ctcaggtatt ttctggggct tgggtctaac
    38521 ggttagtgct tatatctttt cgatttttac agatttgtca ccctttgtgg tggctgcagc
    38581 tcatgatttt ttgagcatct ttatcttact agcttttctc ttggtaaaag aagggaaagt
    38641 tcgcctctca attttcttaa atattcgcaa tgtcagtgtt atcatcggag ccttgctagc
    38701 aggccctatc ggtatgcagg ccaatcttta tgcagttaag tatatcggaa gttctttagc
    38761 ttcatctgta tcggctattt accctgcgat ttcagttcta ttggctttct tctttttgaa
    38821 gcacaagatt tcgaaaaata ctgtatttgg gattgtcttg attattggag ggattattgc
    38881 ccagacctat aaggttgaac aggttaattc cttctacatt gggattctct gtgctttggt
    38941 ttgtgctatt gcatggggaa gtgagagtgt tcttagctcc tttgctatgg aaagtgaact
    39001 gagtgaaatc gaagccctct taatccgtca agtgacttcg ttcttgtcct atcttgtgat
    39061 tgtgctcttc tctcatcagt catttgttgc agtagccaat ggacaattgc taggtctcat
    39121 gattgtcttt gtagcctttg atatgatttc ctatttggct tattatatcg ctatcaatcg
    39181 cttgcaacca gccaaggcta caggcttgaa cgtgagctat gtagtatgga ctgtcttgtt
    39241 cgcagctctt ttcttgggaa catcattaga tatgctgacc attatgacgt cacttgtcgt
    39301 cattgctgga gtttatatta ttattaaaga ataaaggaga ttcgtgtgaa agccattatc
    39361 ttagcagcgg gattgggaac tcgcttgcgt cctatgactg aaaatacccc taaagccttg
    39421 gttcaggtta atcaaaaacc tttgattgaa taccaaattg agtttctcaa agaaaaagga
    39481 atcaatgaca tcatcatcat cgttggttat cttaaagaac aattcgatta tttaaaagaa
    39541 aaatacggtg ttcgtctcat tttcaatgat aaatacgctg actacaataa cttttactct
    39601 ctctatcttg taaaagaaga attggccaac agctatgtta ttgatgcaga taactatctc
    39661 tttaaaaata tgttccgcaa tgatttgact cgttcgactt attttagtgt ttatcgtgaa
    39721 gattgtacca acgaatggtt cttggtctat ggagatgact acaaggttca agacattatt
    39781 gttgatagca aggcaggtcg catccttagt ggtgtatcct tctgggatgc tccaactgca
    39841 gaaaagattg tcagctttat cgataaggct tatgcaagtg gcgaatttgt tgatctctac
    39901 tgggacaata tggttaagga taacatcaaa gagctagatg tctatgttga agaattagaa
    39961 ggcaatagca tctatgaaat cgatagtgtc caagactatc ataaattaga agaaattctt
    40021 aaaaacgaaa attaaaagat tccaacatct gacaaaatag tcggatgttt tttgattttt
    40081 tacgaacttt tacgaataga tagatgagta gaaaaagaaa tggagttatt tatgaaaatc
    40141 acaaactatg aaatctataa gttaaaaaaa tcaggtttga ccaatcaaca gattttgaaa
    40201 gtgctagaat acggtgaaaa tgttgatcag gagcttttgt tgggtgatat tgcagatatc
    40261 tcaggttgcc gtaatccagc cgtttttatg gaacgttatt ttcagataga cgatgcgcat
    40321 ttgtcgaaag agtttcaaaa atttccatct ttctctattt tagatgactg ttatccttgg
    40381 gatttgagtg aaatatatga tgcgcctgta cttttatttt acaagggaaa tcttgacctc
    40441 ctgaaattcc cgaaggtagc ggtcgtgggc agtcgtgctt gtagcaaaca gggagctaag
    40501 tcagttgaaa aagtcattca aggcttggaa aatgaactgg ttattgtcag tggtctggcc
    40561 aagggcattg acacagcagc tcatatggca gctcttcaga atggcggaaa aaccattgca
    40621 gtgattggaa caggactgga tgtgttttat cctaaagcca ataaacgctt gcaagactac
    40681 atcggcaatg accatctggt tctaagtgaa tatggacctg gcgaacaacc tctgaaattt
    40741 cattttcctg cccgtaatcg catcattgct ggactttgtc gtggtgtgat tgtagcagag
    40801 gctaagatgc gttcaggtag tctcattacg tgtgagcgag caatggaaga aggacgcgat
    40861 gtctttgcta ttcctgatag cattttagat ggactatcag acggttgcca tcatttgatc
    40921 caagaaggag caaaattggt caccagtggg caagatgttc ttgcggaatt tgaattttaa
    40981 aaatgaccta agctagaatt ctaagaaaaa atcaatttta agagaaaatg aacccaacat
    41041 ttccataata aaacgcatat tagcaagttt ttaacacttg ataatatgcg ttttttctaa
    41101 gtggattagt agagtagagg atttttctca tataatactc ttcgaaaatc tcttcaaact
    41161 acgtcagctt ccatctgcaa cctcaaaaca gtattttgag ctgacttcgt cagtcttatc
    41221 tacaacctca aagcagtgct ttgagcaacc tgtggctagc ttcctagttt gcgctttgat
    41281 tttcattgag tataagggaa agtatagtga attgaaataa gatgtgaaca actctatcag
    41341 gaaagtcaaa ttaatttata gaaatatttt agcagccaag gtgtactgtt atagattcaa
    41401 tacactataa tttagtgtaa ttgagaaagg agaaatgatt gtgattgatg ttggctaggt
    41461 tatgttcaat gattcctacc gtctcaaatc ttgtcagtaa ggaaaaataa attcttcaaa
    41521 agtagagatt acaaggcttg tttaagaaag aattcaaaga ccttgacaaa taaaaataaa
    41581 atggttatta taagaaatgg tctaaaatag atgatgatac ttttcgaaaa tctttttacg
    41641 tcagctcagc tttgccttgc tgtgttttga gcaagctacg gttagcttcc gagtttgatt
    41701 ttcatttact agaaatgaaa ctgatgagag atatcagtag acatttgagt caggatatta
    41761 tggaaaatga taaaaagagc ttgtgagatt ggcatatcag actactaaag tattgagttt
    41821 gttaggattt tagcgactag ttagctggga aaggaagata tttgtgacaa ataataaact
    41881 gtattcgttg atagaattta gaaataaaat atatgaagaa ttagaacttt ccagaagtga
    41941 tttagcgatt ttactatgtg ccatgcttat cgcctctatc ggattaaata tggattcgac
    42001 tcccgtgatt attggagcca tgttaatctc tcctttgatg acacctattc tgggagtggg
    42061 gctctctcta gctatatttg attttaaatt gttaagaaaa tcttttaaaa tattagctat
    42121 tcaaattctt gccagtctaa tagcttcaac actttatttt tatctttctc ccatttcgta
    42181 tgctagttcg gagattgttg ctagaacctc tccgactatt tgggatgttc tcattgcttt
    42241 tgtaggaggg atagcaggta ttattggtgc taggaaaaaa gagaccaata atattgttcc
    42301 tggtgttgct attgcaaccg ccttgatgcc tcctctttgt acagtaggtt atgctattgc
    42361 ttctgctaat ctaaaattta tcataggctc ctcttaccta ttcctcatca attgtagctt
    42421 tattgtcatt gcgacttata taggtgtcag gttgatgatg gttaagaaac attattttaa
    42481 agataatgaa gaagactcta aaatgcgtag gattttgctt ctagttgctg ttttgctgat
    42541 gattccgagt ttcatctctg caacgacttt agtgagagaa acgttgaaaa aagagtccct
    42601 taagaaattt atatcagagc agtttcaggg gtataatatt ttgaaaaaaa cctattctaa
    42661 aaagactcat accctaaagc taaccatttc aggaaattat ttgacagaag aagaactcga
    42721 tatgatttca agtaagagag gtgactatgg tttaagtgat gtttctgttc aagtttcaca
    42781 attgtctgat tcagaacaac ttagtaagga agagctggtg gagtatttct tccagtatat
    42841 caaggataag gaagcaaaag aaaaggagaa agccaataaa tttgatacag agtctgagga
    42901 gcaataattt cttgagaata gctggtttct ctcgtgagtc ttctatgtat atcaaaggaa
    42961 gactgaggtt ttaagtataa aacttttctt ctattatagt agctaagtct tgacagggtt
    43021 caaaaaatgg tttacacttt ataaagttta ttactttgaa aaggtgtgat actgtggcta
    43081 cggcaacaaa aaagaaaaaa tcaacagtta aaaaaaatct agtcatcgtg gagtcgcctg
    43141 ctaaggccaa gacgattgaa aaatatctag gcagaaacta caaggtttta gccagtgtcg
    43201 ggcatatccg tgatttgaag aaatccagta tgtccgtcga tattgaaaat aattatgaac
    43261 cgcaatatat taatatccga ggaaaaggcc ctcttatcaa tgacttgaaa aaagaagcta
    43321 aaaaagctaa taaagttttt ctcgcgagtg acccggaccg tgaaggagaa gcgatttctt
    43381 ggcatttggc ccatattctc aacttggatg aaaatgatgc caaccgtgtg gtcttcaatg
    43441 aaatcaccaa ggatgcagtc aaaaatgctt ttaaagaacc tcgtaagatc gatatggact
    43501 tggtcgatgc ccaacaagct cgtcggatct tggatcgctt ggtagggtat tcgatttcgc
    43561 ctattttgtg gaagaaggtc aagaagggct tgtcagcagg tcgcgttcag tccattgccc
    43621 ttaaactcat cattgaccgt gaaaatgaaa tcaatgcctt ccagccagaa gaatactgga
    43681 cagttgatgc tgtctttaaa aagggaacca aacaatttca tgcttccttc tatggagtag
    43741 atggtaaaaa gatgaaactg accagcaata acgaagtcaa ggaagtcttg tctcgtctga
    43801 cgagtaaaga cttttcagta gatcaggtgg ataagaaaga gcgcaagcgc aatgctcctt
    43861 taccctatac cacttcatct atgcagatgg atgctgccaa taaaatcaat ttccgtactc
    43921 gaaaaaccat gatggttgcc caacagctct atgaaggaat taatatcggt tctggtgttc
    43981 aaggtttgat tacctatatg cgtaccgatt cgactcgtat cagtcctgta gcgcaaaatg
    44041 aggcggcaag cttcattacg gatcgttttg gtagcaagta ttctaagcac ggtagcacgg
    44101 tcaaaaacgc atcaggtgct caggatgccc atgaggctat tcgtccgtca agtgtcttta
    44161 atacaccaga aagcatcgct aagtatctgg acaaggatca gcttaagcta tataccctta
    44221 tctggaatcg ttttgtggct agccagatga cagcggccgt ttttgatacc atggctgtta
    44281 aattgtctca aaaaggggtt caatttgctg ccaatggtag tcaggttaag tttgatggtt
    44341 atcttgccat ttataatgat tctgacaaga ataagatgtt accggacatg gttgttggag
    44401 atgtggtcaa acaggtcaat agcaaaccag agcaacattt cacccaaccg cctgctcgtt
    44461 attctgaagc gacactgatc aagaccttgg aggaaaatgg ggttggacgt ccatcaacct
    44521 acgcgccaac cattgaaacc attcagaaac gttattatgt tcgcctggca gccaaacgtt
    44581 ttgaaccgac agagttggga gaaattgtca ataagctcat cgttgaatat ttcccagata
    44641 tcgtaaacgt gaccttcaca gctgaaatgg aaggtaaact ggatgatgtc gaagttggaa
    44701 aagagcagtg gcgacgggtc attgatgcct tttacaaacc attctctaaa gaagttgcca
    44761 aggctgaaga agaaatggaa aaaatccaga ttaaggatga accagctgga tttgactgtg
    44821 aagtgtgtgg cagtccaatg gtcattaaac ttggtcgttt tggtaaattc tacgcttgta
    44881 gcaatttccc agattgccgt catacccaag caatcgtgaa agagattggt gttgagtgtc
    44941 caagctgtca tcagggacaa attattgagc gaaaaaccaa gcgtaatcgc ctattctatg
    45001 gttgcaatcg ctatccagaa tgtgaattta cctcttggga caagcctgtt ggtcgtgact
    45061 gtccaaaatg tggcaacttc ctcatggaga aaaaagtccg tggtggtggc aagcaggttg
    45121 tttgtagcaa aggcgactac gaggaagaaa agattaaata agaggagggg cccgaaagta
    45181 aatttcaggc tccttttggt tagaacttga caaaatacat cattttatgc gaaactagaa
    45241 gaagattatt ttaactagga gaagttatgc gtcttatcta tctgataatt ggttttttat
    45301 cactggcctt ggctattgtt ggggttgttt tacccttatt gccgacaacg cctttccttt
    45361 tgttgtctat tgcttgtttc tccagaagtt ccaagcgttt cgaagactgg ctttatcata
    45421 ccaagctcta tcaaacatat gtagctgatt ttcgcgagac taagtctatt acgcgtgaac
    45481 gaaagaaaaa aatcatcgtc tctatctacg tcttgatggg aatttctatt tattttgcac
    45541 ctcttttacc agtcaaaatt ggtctgggtg ctttgaccat ctttatcact tattatctct
    45601 tcaaggtcat tccagacaaa gaatagttaa aacagtagtt atttgccttg ataaaattga
    45661 aagcatattc ataacaatat gatataataa atttgaagta atattcaagg agaatcaaat
    45721 gatttacgaa ttttgtgctg aaaatgtgac tttacttgaa aaagcgatgc aggctggagc
    45781 tcgtcggatt gaactctgtg ataatctagc agttggtggg acaacaccca gctatggagt
    45841 gactaaggca gcggttgaac tggcagctaa ctacgataca accatcatga ccatgattcg
    45901 gccacgtggt ggtgactttg tctataatga cctagaaatt gctatcatgc tagaagacat
    45961 tcgtttgact gctcaggctg gaagtcaagg ggttgtattt ggaactttaa ctgctgataa
    46021 aaagttggat aagcctaatc tggaaaagtt aattgctgca tcaaaaggaa tggaaattgt
    46081 ctttcacatg gcctttgatg aactaagtga tgaagatcaa ctggaagcta ttgactggct
    46141 cagtcaagcc ggtgtcactc gtatcctaac tcgtgctggt gtgtctggcg actccttaga
    46201 aaaacgtttt gttcactatc acagaatttt ggagtacgct aaaggtaaaa ttgaaattct
    46261 accaggtggg gggattgacc ttgaaaaccg tcaaaccttt atcgaccagg tgggggtaac
    46321 acaattgcat ggtactaagg ttgtttttta aaaaatagaa aggaactgct agccttgggt
    46381 agcagttttc acttatgttt gaaattttta aatcctatca atttaatcaa gaaaaggctc
    46441 atgattatgg ttttatagaa aatagcgaag tctggacata tagttgccag attttgcaag
    46501 gtgactttgt catgactgtg tccatcactg ctgataatgt gaactttcaa gtctttgacc
    46561 aagagactgg tgacctctat cctcacgttc atatggaaag catgagggga agttttgtcg
    46621 gaaatgtccg tgaggcttgt ctggagattc tttaccagat tcggaaggct tgttttgatg
    46681 tgcaagattt tatctgtcat cagactaagc gtatcatgac tcaagttcag gaaaagtatg
    46741 gaaaccagtt ggagtatctg tgggaaaaat cgcctgatac agctgtattg cgccatgaag
    46801 gcaatcaaaa gtggtatgcc gtcttgatga aaatctcttg gaataagctg gaaaagggca
    46861 gagaaggaca agtggaagca gtcaacctca agcatgacca agtagctaat ttgctttcac
    46921 aaaaggggat ttatccagcc ttccatatga gcaagcgcta ctggattagt gtgtcccttg
    46981 atgatacttt atcagatgaa gaagtactgg aattgataga aaaaagttgg aacttaacct
    47041 ctaaaaaatg aaatatttta ataattttca tgaactttca attagctaaa tattctttac
    47101 tgaagagatt tttagaaaat ataggattta ccacactaga ggaatatggt gccatcttca
    47161 aatacctgat tgagaatgtc aagacggatc gtcagatcat ctattcgcct cactgtcatg
    47221 atgacctcgg aatggcagtg gcaaatagcc ttgctgctgt caagaatggt gcaggacgtg
    47281 ttgaagggac tatcaatggt attagggagc gagctgaaaa tgctgctttg gaagaaattg
    47341 cagtggctct caatattcgc caagattact accaagtaga aaccagtatt gtcctaaatg
    47401 agaccatcaa tacgtcagaa atggtttctc gcttctctgg tattccagtt cctaaaaaca
    47461 aagccgtcgt tggtggcaat accttctccc acgaatctgg tattcaccaa gatggagtcc
    47521 ttaaaaatcc tctcacttat gagatcatca cacctgaatt ggttggtgtt aagattctgc
    47581 ttggaaaatt atctggtcgc catgcttttg ttgagaaact gagagaattg gccctagatt
    47641 ttacagaaga ggatatcaaa ccactctttg ctaagttcaa ggcactggtc gataagaagc
    47701 aagaaatcac agatgcagat attcgagctt tggtagctgg aaccatggtt gaaaatccag
    47761 aaggcttcca ctttgatgat ttacaacttc aaactcatgc agataatgac attgaagcgc
    47821 tcgttagcct agccaatatg gatggtgaga aagtcgaatt taatgcgaca gggcaaggtt
    47881 ccgttgaagc aatctttaat gctatcgata agttctttaa ccaatctgtt cgtttggtgt
    47941 cctacactat cgatgcggta acagatggaa tcgataccca ggatcgggtt ttggtcactg
    48001 ttgaaaacag agatacagaa accatcttta atgcagcagg gcttgatttt gatgtgttga
    48061 aggcttctgc tattgtctat ataaacgcta atacctttgt tcaaaaagag aatgcaggtg
    48121 agatgggacg cagtgtttct taccacgata tgcctagtgt gtaaaggaga aggctatggc
    48181 aaagaaaata gtagctctag caggagacgg aattggccca gaaatcatgg aggttggttt
    48241 agaagttctg gaggctctag ctgaaaaaac aggttttgac tatgagattg acagacgacc
    48301 gttcggaggt gcagatattg atgcagcatg acctccctta cctgatgaaa cccttaaggc
    48361 aagtagggaa gcagatgcta tcctactagc agctatcggt agtcctcagt atgatggagc
    48421 agtggttcgc cctgaacaag gcctgatggc tctccgtaag gaactcaatc tttacgctaa
    48481 tattcgtcct gtaaaaatct ttgacagtct caagcatttg tcactactca aactggaacg
    48541 aattgctggt gtagactttg tcgtggtgcg tgaattgaca ggcgggattt actttggaga
    48601 tcatattctt gaagagcgca atgcgcgtga tatcaacaac tatagctatg aggaagtgga
    48661 gcggattatt cgcaaagcct ttgaaattgc aagaaatcgc agaaaaatcg ttactagtat
    48721 cgataagcaa aatgttctag cgacctcaaa actctggcgg aaagtagctg aggaagtcgc
    48781 acaggatttc ccagatgtaa ccttggaaca tcagctggta gactcagctg ctatgcttat
    48841 gattaccaat cctgctaagt ttgatgttat tgtaacggag aatctttttg gagatatttt
    48901 atctgatgaa tcaagcgtct tatctggtac acttggggtt atgccatcag ccagtcattc
    48961 tgaaaatgga ccaagtctct atgaacctat tcacggttca gcacctgata ttgcaggtca
    49021 aggaattgcc aatcctattt ccatgatttt atcagtttcc atgatgttga gagatagttt
    49081 cggacgttat gaggatgcag agcgtatcaa acgtgctgtt gagacaagtc tggcggcagg
    49141 aattttaacg agagatatag gaggtcaggc ttcaacaaag gaaatgacgg aagctattat
    49201 tgcaaggtta tgaagttaga cgaaaaaatt actctagtcc ttttgatttg gaatgtcatc
    49261 attttcttga tttatggtat tgacaaatct aaggcaagga gaagagtttg gcgcatccct
    49321 gagaaaatct tacttatttt agcctttact tttggtggtt ttggtgcctg gctagcagga
    49381 atcatctttc accacaagac tcgaaaatgg tactttaaaa tagtttggtt tcttgggatg
    49441 gtgaccacac tagtagcctt atattttatt tggaggtaat ggatggcagg gtcttcgagg
    49501 gaatacgctg cttgggctct agcggactat ggttttaagg tcgtgattgc aggatctttc
    49561 ggtgacattc attacaataa tgaactcaat aatggcatgt tgccaatcgt tcagcctaga
    49621 gaggttagag agaaactagc ccagctaaaa ccaaccgacc aggtaactgt ggacttggaa
    49681 caacaaaaaa tcatctcacc agttgaagaa ttcaccttcg agatagatag cgagtggaaa
    49741 cataaactcc taaatagttt ggatgatatc ggtattacct tgcagtatga agagttgatt
    49801 gctgcttatg aaaaacaacg accagcctac tggcaggatt agaaaaaata gaaaaggaga
    49861 tatagtaaac tgaaataaga tgtaaacaaa tgaattggag cttaacatcc atttccagca
    49921 attttttaga aactacagtg gactattctg gattcaacac attataaaat tatgacaaaa
    49981 cacattcaca agaaggctac gacattttaa aaggtgaggg cggatgtatc gtttgcccta
    50041 ctaaagttgg ttacattatc atgaccagtg acaaggcagg acttgagcgt aagttcgcag
    50101 ccaaagaacg taagcgtaac aaaccaggtg ttgttctctg cggtagcatg gatgaacttt
    50161 gcgctttagc gcaactcaac ccagaaattg aagcattcta ctaaaaacat tgggatgaag
    50221 atattcttct tggttgtatc cttccttgga aaccagaagc ctttgaaaaa ctcaaagcat
    50281 acggggatgg ccgtgaagaa cttattactg atgtacgtgg tactagctgt tttgttatca
    50341 agtttggaaa agcaggtgaa caattggctg ccaagctttg ggaagaaggt aaaatggtct
    50401 acgcctcatc tgcttcaatg acaaaacgat tgaaactcgc tatgagcaag gtgtaatggt
    50461 gtctatggtc gataaggacg gcaaactcat cccagaacaa ggaggagcac gttcaacttc
    50521 accagctcca gttgtgatcc gtaaagggct tgacattgat aaaatcatga tgcacctgtc
    50581 agatactttt aactcatggg actaccgtca ggttgagtat tattaggata gagaagaagt
    50641 ctagtgttat gagatattaa agctcctaac actgggcttt tgtttagaat ttcttttctt
    50701 tttctatagg atatggtatt ctatgtagaa aatatatgtt aataagtaat gccaatattt
    50761 aaacatcatt agtaaaagga gttagattga tgaataaaag aaaagttagt ttagaagatt
    50821 tttataaatg gtatagtcta aataaagaag agttattaaa taaggcaact gttggtgaaa
    50881 agtttaatga taaattaaaa gaagagtttc tccaggaatg gcctttggat aggattttaa
    50941 caatgtcaat cgatgaatat gtaataggaa agggacagca aaataagtct ttatgctacg
    51001 ctcttgagaa gggaaaatac aaaaatctat ttcttggaat ttctggtggc tcagcttcaa
    51061 aatttggtat ttattggaat aaaaaaacaa acaaatataa agatcaagct aataatgaga
    51121 tttcagagtt ggatcagcga ttttcaaaat taaaatcaga tttgtatgaa attatcaaag
    51181 aaggtattcg ttttaacttt gaaaatccta tttttgatat gaaaagatca acaaatgaat
    51241 ttattggtcg ttctgctatg gtgacaaaat tactttgtat ctatactgag ggagatcctt
    51301 tctttggtgt aaatattaat agtcagaaag aattttggaa ccactttgtt tctcagacaa
    51361 atcaaggtgg accttatctg caaaatcata aaataattga actggtgtcc aaaacttatc
    51421 ctgagttgga gccatcgaaa ttaggaacta tgctttttga gtattctaag ctttttatgg
    51481 aaaataagga agacaatagt acaatggatt catcaaacaa ttttagtcat caattaactc
    51541 aatctctatt aaagtctcca aaccttatcc ttcgtggtgc tcctggcaca ggaaagactt
    51601 atcttgctaa agaaattgcc aaagaattaa cggatggtaa cgaagaccaa atcggatttg
    51661 tacaatttca cccatcctat gattatacgg attttgtaga aggtttaaga ccagtatcaa
    51721 atggggatgg agctattgag tttaggctac aggacggtat ttttaaagat ttttgtcaga
    51781 aagcaaaaga aacccaattg attggaggac aagataattt tgatgaggct tgggattctt
    51841 acttagaata tataaatgtt gctgaagaaa aagaatatat aacaaaaaca tcttacttat
    51901 ctgttaatag tagacaaaat ttgtcagtaa attatgatag tggtgttcca ggatggtcac
    51961 tacctagcaa atatgtttac gagttgtata aagataaaaa ttataataag caagaatact
    52021 acaaaagtgg tggaaaaact gtcctagaaa cattgagaaa gagatttggt ttgaaagact
    52081 atatttctcc agaagaggtt gaaacagaca agaaatttgt tttcatcatc gatgagatca
    52141 atcgtgggga gatttctaag atttttggcg aactcttttt ttctatcgac cctggctatc
    52201 gtggtgaaaa aggaagtgtt tctacccaat atgcaaatct acacgaaact gatgaaaagt
    52261 tctatatccc cgaaaatgtt tacatcatcg gaactatgaa tgatattgat cgttcagtgg
    52321 atacctttga ttttgctatg cgtcgtcgtt ttcgttttgt tgaagttact gccgagggtc
    52381 aagttggcat gttggataaa gagttgaata tccatgcaga agaagcaaaa attcgtctaa
    52441 gaaacttgaa cgctgctatc gaaaatgttc aggaattaaa cagtcattat catattggac
    52501 caagttattt tcttaagttg aaggatgtag attttgacta tgaattactc tggtctgatt
    52561 atattaagcc tctcctagaa gactacttgc gaggttctta tgatgaggtt gaaactttgg
    52621 aaactttgaa aaaagcattt gaactgacaa ataatgagca aaaagatcag gcagtagctg
    52681 atgacaatga aggtgatgaa aacgatgatg cggattactg ataatcaaca caagattatt
    52741 aaagaaaaat ttgttgaaga atatcctaaa ctaagcaatc ttcttttaga cagaaccttg
    52801 gaaagtctat cccaagatga acgtattttc atttttccaa atgatttgac tcatactcct
    52861 gatttggata aggaccaaaa gatttttgaa acagtcaatc agaaaatcaa gacagggaac
    52921 gtgattggtt ttcttggata tggtcaggaa agattaacga tttcctcacg attttctgat
    52981 gagagtaatg accatttttt gcattatctc ttaaacaagg ttctttatat caatctcact
    53041 agtttagatg ttgctttgtc tcgtgaagag aggctttatc aacttttgat gtatctcttc
    53101 cccaagtatc tacaagctgc tattcgaaaa ggtctttata aggaatatca tcgattttct
    53161 cataacgaca gtcatgttaa gggagtgatt gttgtaagaa accatctcaa gaaaaatctt
    53221 cctttcacgg gaaatattgc ctacacaacg agagagttca tctatgataa tcccctcatg
    53281 cagttggtcc gtcacactat tgaatacatt aagaatcaga aaagcattgg tcaaggggta
    53341 ctagataatc tctcaactag tcgtgaaaac gtatctgaaa tcgtgcgtgt aacgccctct
    53401 tataaactag ctgatcgtgc taagattact cggagaaatc aatctaaacc tatacgtcat
    53461 gcatactttc acgagtacag aaacttacaa gaactttgtc tgatgatcct aaaccaagaa
    53521 aagcacggtt tagggtatca agatcaaaaa atctatggta ttctctttga tgttgcctgg
    53581 ctttgggaag agtatgttta caccttgttg ccaaaaggtt ttgtacatcc cagaaataag
    53641 gataagacgg atggaatttc agtattttct gttgggaaac gaaaagtata tccagatttt
    53701 tatgacagag aacgaaagat tgttctagat gcaaaatata aaaaactgga attgactgaa
    53761 aaaggaatca accgtgagga cttattccag ctgatttcct attcttatat tttaaaagct
    53821 gagaaggctg gactgatttt tcctagtatg gagcagtcag taaatagtga aataggaaaa
    53881 gtagctggct atggagctca attgaagaag tggtctattc gaatccctca gaatgcctca
    53941 ttctatagta cattttgtaa aatgatggaa aattcagaag aaaattttaa agcgattatt
    54001 gatgaagaag tggggagaaa ataatttccc ctctttcttt tatttttaac acaagtaaaa
    54061 cccgaacgat atattttaat tcataaaata atttgacaaa aactgtactt tggtttataa
    54121 taaattaagg aaacgtcgga aaaggcgtag tgatgcaaga gcataggtag gtcattacaa
    54181 aagaaacgag acatcgatat gttaaatgaa tttccaattt ttgattacga agatattcaa
    54241 ttgattccaa ataaatgtgt cattaaaagc cgtgcagaag cggatacaag tgtcacttta
    54301 ggaaatcaca cctttaaact acctgttgtg ccagcgaata tgcagacgat tttggatgaa
    54361 aatgtagcag agcaactggc taaaggtggt tacttctaca ttatgcaccg ttttgatgag
    54421 gcaggacgca ttccttttat taaacgcatg cacgatcaag gactcattgc ttctatctct
    54481 gtcggtgtta aggactatga gtatgatttt gttagccagc tcaaggctga tgctcctgag
    54541 tatatcacta ttgatattgc tcatggtcat gcggatagcg tgatttctat gattcaacac
    54601 atcaagaaag aattgccaga tacctttgtc attgctggaa atgtgggaac accagaagct
    54661 gtgcgtgaat tggaaaatgc tggtgcggat gctactaagg tcggaatcgg tcctggtaag
    54721 gtttgtatca ccaaggttaa gactggtttt ggtacaggtg gttggcagtt ggctgctcta
    54781 cgctggtgtg ccaaggctgc gcgtaaaccg attatcgctg atggaggaat tcgtactcac
    54841 ggtgatattg ccaagtctat ccgcttcggt gctagcatga tcatgattgg ttccctcttt
    54901 gcaggacaca ttgaaagtcc agggaaaacg attgaagtcg atggtgaaca gttcaaagaa
    54961 tattatggtt cagcctcaca atatcaaaaa ggtgcttaca aaaatgtgga aggcaaacgt
    55021 atcttgcttc ctgctaaagg tcatctgcaa gacactttaa ctgagatgga acaagacctt
    55081 caaagtgcta tttcttatgc aggtggacgt caggttgctg accttaaaca cgttgattat
    55141 gtgatcgtga aaaactccat ctggaatgga gatgcttccc actaagacgg ggtctttgac
    55201 caaaaaactt gttattagag caaatttctg ttataataaa acaagtttcc acccttagtg
    55261 taatggatat cacgtaagat tccggttctt gagatggggg ttcgattccc tcagggtgga
    55321 tgtaaacatc ctaaaaagcc tttaataggg cttttttctt tatcctgacc caaatttgcc
    55381 gctaaaactg agaatctctg tctaaagaat tcccaaatgc tttccagtcc cgttttagag
    55441 tgactcaggg ggcttttttt gatataataa aaaggactat tatcagttag aaagaagttg
    55501 gtatgaaaga attacaaact gtactaaaga atcattttga aatcgaattt gcagacaaaa
    55561 agttactgga aactgccttt actcatacga gttatgccaa tgagcaccgc ctcttaaaaa
    55621 tttcacacaa tgaacgcttg gaatttttag gagacgctgt tctacagtta ttgatttcag
    55681 aatatctata taaaaaatat cctaaaaagc ctgaaggtga cctatcaaaa ctccgtgcta
    55741 tgattgtccg tgaggagagt ttagctggtt ttgcgcgtga ttgccagttt gaccagttta
    55801 tcaagttggg taaaggggaa gaaaaatctg gtggtcgcaa tcgtgacacc attcttggtg
    55861 atgcctttga agcctttctt ggtgcccttc ttttggataa ggatgtggca aaggtcaagg
    55921 aatttatcta ccaagttatg attcctaagg tagaagcagg cgaatttgag atgattacag
    55981 actataaaac ccatctccaa gagttgcttc aggtcaatgg tgatgtggct attcgttatc
    56041 aggtgatttc tgaaacaggg cctgctcacg ataaggtctt tgatgtagaa gttcttgttg
    56101 aaggtaagag catcggtcaa ggccaaggtc gttctaagaa attagcagag caggaagctg
    56161 ccaaaaatgc cgttgagaaa gggctggatt catgtattta aaggaaatcg aaattcaggg
    56221 gttcaagtct tttgctgata agaccaaggt cgtttttgac caaggtgtga cggcagttgt
    56281 tggacccaat ggatctggaa agtccaatat tacagaaagt ctgcgttggg ctttggggga
    56341 gtctagtgtc aagagtctcc gtgggggcaa gatgccggat gtcatctttg ctggaacaga
    56401 aagtcgcaaa ccgctcaatt atgcttctgt agttgtgact ctggataatc atgacggatt
    56461 tatcaaggat gcaggtcaag aaatcagggt ggaacgccat atctatcgta gtggagatag
    56521 cgaatacaag attgacggca agaaagtccg tcttcgtgat attcatgacc tcttcttgga
    56581 tactggattg ggacgagatt ccttctctat tatttcccaa gggaaggttg aggagatttt
    56641 taattccaag cctgaggaac gacgagctat ttttgaagaa gctgctggag ttttaaaata
    56701 caagactcgc agaaaagaaa ccgagagtaa actgcagcaa actcaggata atctggaccg
    56761 cttagaggac attatctacg agttggataa tcaaatcaag cctcttgaga agcaagctga
    56821 gaatgcccgt aagtttttag acttggaagg acaacgtaag gctatttatt tagacgttct
    56881 ggttgctcaa atcaaggaaa ataaggcaga actagagtcg acagaagaag agttggctca
    56941 ggttcaagaa ctcttgatga gttattacca aaagcgtgaa aaattagaag aagaaaatca
    57001 aactcttaaa aagcaacgcc aagatttaca ggctgaaatg gccaaagacc aaggcagttt
    57061 gatggacttg actagtctga ttagtgattt agaaagaaaa ttagccctat cgaaactgga
    57121 gtccgagcaa gtggccctga atcaacagga ggcacaagct cgtttggctg ctttggagga
    57181 taagagaaat tcactcagca aagaaaagta tgataaagaa agctctttag ctctgttaga
    57241 gggaaatcta gtccaaaata atcaaaaact caatcgttta gaagctgaat tgctggcttt
    57301 ctcagacgat cctgatcaga tgattgagct cttacgtgaa cgctttgtag ctcttttaca
    57361 agaagaagcg gatgtctcaa accagttgac ccgtattgag aatgagttgg aaaatagtcg
    57421 tcagctttct caaaaacaag cagatcaact agaaaagctg aaagagcaat tagctacagc
    57481 taaagagaag gctagtcagc aaaaagacga gcttgaaact gccaaggtgc aggttcagaa
    57541 attattggct gactatcaag ctattgccaa ggagcaagag gagcagaaaa cttcctatca
    57601 agctcaacaa agtcaactct ttgaccgtct ggatagtctc aaaaacaagc aggccagagc
    57661 tcaaagtttg gaaaatatcc tgagaaatca tagtaacttt tatgcaggtg ttaagagtgt
    57721 tctccaagaa aaagatcgcc taggtgggat tattggtgca gtcagtgagc atctgacctt
    57781 tgatgtttat tatcaaactg ccctagagat tgccttaggg gcaagtagcc agcatatcat
    57841 cgtagaagat gaagagtcgg caaccaaagc tattgatttc ctcaaacgaa acagagtcgg
    57901 tcgtgcaacc tttcttcctt tgaccactat taaggcgcgt acgatttcta gtcagaacca
    57961 agatgctatc gctgtaagcc caggtttcct tgggatggca gatgagttgg tgacttttga
    58021 tactagactg gaagccattt tcaagaactt gctagctacg acggctatct ttgataccgt
    58081 agaacatgcg cgtgaagctg ctcgacaagt tcgttatcag gttcgtatgg tgacattgga
    58141 tgggacagaa ttacgcacgg gtggttccta tgcgggtggt gccaatcgcc aaaataacag
    58201 tattttcatc aagccagaac tggagcaatt acaaaaagaa attgctgcag atgaagcaag
    58261 cttgggttca gaagaagcgg ctttgaagac cttgcaagac cagatggctg cattgacaga
    58321 aagattagaa gccatcaaat ctcaaggaga gcaggtacgt attcaggagc aaggcttgtc
    58381 cctcgcttat cagcaaacta gtcagcaagt tgaagaactg gaaactcttt ggaaactcca
    58441 agaagaggaa ttagatcgtc tttctgaggg agattggcaa gcggataagg aaaaatgtca
    58501 agagagcctt gctactatcg ccagtgaaaa gcaaaatctg gaagctgaga ttgaagaaat
    58561 taagtctaat aaaaacgcca tccaagaacg ctatcaaaat ttgcaggaag aggtggcgca
    58621 agctcgcttg cttaagacag aactgcaagg gcaaaaacgt tatgaagtag ctgatattga
    58681 gcgtttaggc aaggaattgg acaatcttaa tatcgagcaa gaagaaattc agcgcatgct
    58741 ccaagaaaaa gttgacaatc ttgagaaggt tgatacagaa ttgctcagtc aacaggcgga
    58801 agaatccaaa actcagaaaa caaatctcca acaaggtttg attcgcaagc agtttgagtt
    58861 ggatgatata gaaggtcaac tggatgatat tgccagtcac ttggatcaag ctcgccagca
    58921 gaatgaggag tggattcgca agcaaacacg tgctgaagcc aagaaagaaa aggtcagcga
    58981 gcgcttgcgc catctacaaa atcaattaac agaccagtac cagattagct atactgaagc
    59041 actagaaaag gcacatgaat tggaaaacct caatctggca gagcaagagg tgcaggattt
    59101 agagaaggct attcgctcat tgggacctgt caacttggaa gctattgacc agtacgaaga
    59161 agttcacaac cgtctggact ttctaaatag tcagcgagat gatattttgt cagcgaaaaa
    59221 tctgctcctt gaaaccatta cagagatgaa tgatgaggtc aaggaacgct ttaaatcaac
    59281 ctttgaagct attcgtgagt cctttaaagt gaccttcaag cagatgtttg gcggaggtca
    59341 ggcagacttg atattgactg agggcgacct tttaacagct ggtgtggaga tttctgttca
    59401 acctccaggt aagaaaatcc agtcgcttaa cctcatgagt ggtggtgaaa aagctctatc
    59461 ggctcttgcc ttgcttttct ccattattcg tgtcaagacc attccttttg tcatcttgga
    59521 tgaggtggaa gctgcgctgg atgaagccaa tgttaaacgt tttggggatt acctcaaccg
    59581 ctttgacaag gacagccagt ttatcgttgt aacccaccgt aagggaacca tggcagcggc
    59641 tgattccatc tatggagtga ccatgcaaga atcgggtgtt tcaaagattg tttcagttaa
    59701 gttaaaagat ttagaaagta ttgaaggatg acaattaaac tagtagcaac ggatatggac
    59761 ggaaccttcc tagatgggaa tggacgcttt gatatggatc gtctcaagtc tctcttggct
    59821 tcctacaagg aaaaagggat ttactttgcg gtggcttcgg gtcggggatt tctgtctctg
    59881 gaaaaattat ttgctgatgt tcgtgatgac attattttca tcgcggaaaa tggcagtttg
    59941 gtagagtatc aaggtcagga cttgtatgaa gcgactatgt ctcgtgactt ttatctggca
    60001 acttttgaaa agctgaaaac gtcaccttat gtagatatca ataaactgct cttgacgggt
    60061 aagaagggtt catatgttct agatacggtt gatgagacct atttgaaagt gagtcagcat
    60121 tataatgaaa atatccaaaa agtagcgagt ttggaagata tcacagatga cattttcaaa
    60181 tttacaacca acttcacaga agaaacgcta gaagctggtg aagcttgggt taatgaacat
    60241 gtccctggtg ttaaggccat gacaactggc tttgaatcta ttgatattgt tctggactat
    60301 gtcgataagg gtgtagctat tgttgaatta gctaaaaaac ttggtatcac aatggatcag
    60361 gtcatggctt ttggagacaa tcttaatgac ttacatatga tgcaggttgt gggacatcct
    60421 gtagctcctg aaaatgcacg acctgaaatt ttagaattag caaagactgt gattggtcac
    60481 cataaggaac ggtcggttat agcttatatg gagggcttat aatggcagat ataaaattga
    60541 ttgcattgga cttggacggg accttgctga ctactgataa aaggctgacg gatcgtacca
    60601 aggaaacctt gaaagctgcg cgtgatcgtg gtatcaaggt cgtattgaca actggtcgtc
    60661 ccttaaaagc catggatttc tttctccatg agttagggac tgacggtcag gaagatgagt
    60721 ataccattac ttttaatggt ggattagttc agaaaaatac aggagaaatc cttgataaaa
    60781 cagtcttttc atatgatgat gtggcacgtt tgtatgaaga aacagagaaa ttatcactgc
    60841 ctcttgacgc tatctcagaa ggaacagttt atcaaatcca atcggaccaa gaaagtcttt
    60901 atgccaaatt caatccagct ttgacttttg ttccagttga ctttgaagac ctgtctagtc
    60961 aaatgaccta caacaaatgc gtgaccgcct ttgctcaaga acccttggat gcagccattc
    61021 agaagatttc tctagaattg tttgaccaat atgaaatctt taaatcacgt gaaatgttgc
    61081 tagaatggtc accaaagaat gttcataaag caacaggttt ggcaaaacta atcagccatc
    61141 ttggaatcga ccaaagccaa gtgatggctt gtggtgacga ggccaacgac ctctctatga
    61201 ttgaatgggc aggtcttggt gttgctatgc aaaacgctgt tcctgaagta aaggcagccg
    61261 caaatgtagt gacgccgatg accaacgatg aggaagctgt cgcctgggct atcgaagaat
    61321 atgtgctaaa ggagaactaa gatatgggat tgtttgaccg tttattcgga aaaaaagaag
    61381 aacctaaaat cgaagaagtt gtaaaagaag ctctggaaaa tcttgatttg tctgaagatg
    61441 ttgatcttac cttcacagaa gctgatgaag ttcctcagga agaagcagag gttgaaattg
    61501 ttgaacaagc tgtgttccaa gaagaggaaa tccaagacac agttgaagaa agtcaggatt
    61561 cagagccagc tgtaggggtt tctcaagaag aaatagaaga attaccaaac tcagaagaat
    61621 taccagagga agagaagctt gagcacgaag gaactgtaga agaaaataat tctgaagtgc
    61681 ttgaaccaga agctcctcaa acagaagaaa ctgttcagga aaaatatgac cgcagtctta
    61741 agaaaactcg cacaggtttc ggtgcccgct tgaatgcctt ctttgctaac ttccgctctg
    61801 ttgacgaaga atttttcgag gaactggaag aactgctgat tatgagtgat gttggtgtcc
    61861 aagtcgcttc taacttaacg gaggaactac gttacgaagc caagcttgaa aatgccaaga
    61921 aacctgatgt acttcgtcgt gtcatcattg agaaattggt tgagctttat gaaaaggatg
    61981 gtagctacga tgaaagcatc cacttccaag ataacttgac agttatgctc tttgttggtg
    62041 tgaatggtgt tgggaaaaca acttctatcg gaaaactagc ccaccgctac aaacaagctg
    62101 gtaagaaggt catgctggtt gcagcagata ccttccgtgc gggtgcagta gctcagctag
    62161 ctgaatgggg ccgacgagta gatgttccag tagtaactgg acctgaaaaa gctgatccag
    62221 ccagcgtggt ctttgatggt atggaacgtg ccgtggctga aggtatcgat attctcatga
    62281 ttgatactgc tggtcgtctg caaaataagg ataaccttat ggctgagttg gaaaagattg
    62341 gtcgtattat caaacgtgtt gtgccagaag caccacatga aaccttcttg gcacttgatg
    62401 catcaacagg tcaaaatgcc ctagtacagg ccaaagaatt ttcgaaaatc acacctttaa
    62461 cgggaattgt tttgactaag attgatggaa ctgctcgagg aggtgtggtt ctagccattc
    62521 gtgaagaact caatattcct gtaaaattga ttggttttgg tgaaaaaatc gatgatattg
    62581 gagagtttaa ctcagaaaac tttatgaaag gtctcttgga aggcttaatc taatcagaag
    62641 caaaaatcct gcaaggtaca aacttgcagg atttttttat tcgaaacgac catcttgacg
    62701 ataggcgata tctggttgcc aagtccattt ggcaccgaat ttttcaagta ggtcaaagct
    62761 ggcttgaggt cccatgcttc cagctttata gtcatgaagt ggggcaccat tttcagccca
    62821 gagcttttca atacggtcaa tcaacttcca tgacgcacaa acttcatccc agtggctaaa
    62881 gttagttgag ttgttattta ggacatcata aatcaatttt tcgtatggtt ctggagaagc
    62941 accagttgca gtcgcatctg tacggtaatc aagtgagtta ggagccaagt taaattcttc
    63001 tcctacttgc ttcccattta ggctaagaga gaagccttct gttggttgaa tatagatggt
    63061 caaaatattt ggagcaagtg gttctccaaa gatagaatcc atttgtttaa agacgatgtt
    63121 gacatgagtt cctttttcag tcagtcgttt acctgtacgg aaaaagaaag gaacaccacg
    63181 gaatcgatcg ctgtctacaa agaaggcacc agatgtaaag gtttcagttg ttgattctgg
    63241 attcacattt ggctcgctac gataagagat gtatttcatg ccatcaatct taccagagcg
    63301 gtattgccca cggataaagt gttctttgag ttcttcatca gttggatgat agaggttttt
    63361 aaagacctta atcttttcag cacgaatctc gtcttttgtg aagcttgctg gtttgtccat
    63421 ggcgaggagc gaaagaagtt gtagagtgtg gttttggacc atgtcacgga gggcaccgga
    63481 ttggtcatag tagccaccac gttcttctac acccaagcgc tccgcaaagg taatttgaac
    63541 attgtcgata aaatccttgt tccaaacgtt ttcaaaaatc aagtttgcaa agcgaactgc
    63601 aaagatgctt tggatcattt ccttaccaag ataatggtcg atacggaaaa tttgttcttc
    63661 gtcaaatgtt gctaggagtt cgtcattcaa cttgtttgca gttgcgtaat ctgtaccaaa
    63721 tggtttttca acgatcaagc gctcaaaacc tttgccatcg acaatgtttt cagatttgag
    63781 gtgtttggca atggttccaa agaactgagg tgccatagac aagaagaaga gcttattgtg
    63841 ttcagcttgg tatttttcat taagctcagc ttgtaattga cgcaaagcaa tataatgttc
    63901 cgaatcattg acatcatggc tttgatagta gaagtggcta gcaaattctt gggcttgctc
    63961 ggtactatct gccaaatcaa ggatggactc gacaactaca gattcaaaat attccttact
    64021 ccaaggtcta cgggcagttc caataacggc aaagtgcttg gaaagattgc cggatttata
    64081 tagtctaaaa agggaagggt agagcttgcg tttagccagg tctccactcg caccgaaaat
    64141 tgtaacaata accttagatg acatctagct acctaatttc tatttttatt cctagtcttg
    64201 ctaggtatga ggaaacctca tttcataaac ttaattctaa cataattttc cgaaaaatca
    64261 aaaattccaa tacgaggtag aaaaac
//
LOCUS       DAVHBD010000005        62454 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000005 DAVHBD010000000
VERSION     DAVHBD010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62454
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.005"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(141..1010)
                     /locus_tag="VVK04_000324"
     CDS             complement(141..1010)
                     /locus_tag="VVK04_000324"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU3989029.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(1012..2298)
                     /locus_tag="VVK04_000325"
     CDS             complement(1012..2298)
                     /locus_tag="VVK04_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU3989030.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VVK04_000326"
     CDS             complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VVK04_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU3989031.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3386..4420)
                     /locus_tag="VVK04_000327"
     CDS             complement(3386..4420)
                     /locus_tag="VVK04_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU3989032.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVAIFKL"
     gene            complement(4449..5882)
                     /locus_tag="VVK04_000328"
     CDS             complement(4449..5882)
                     /locus_tag="VVK04_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU3989033.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5898..6884)
                     /locus_tag="VVK04_000329"
     CDS             complement(5898..6884)
                     /locus_tag="VVK04_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU3989034.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFKAYS
                     QIHRFLKDHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6886..7989)
                     /locus_tag="VVK04_000330"
     CDS             complement(6886..7989)
                     /locus_tag="VVK04_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU3989035.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7979..8824)
                     /locus_tag="VVK04_000331"
     CDS             complement(7979..8824)
                     /locus_tag="VVK04_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU3989036.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFFPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VVK04_000332"
     CDS             complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VVK04_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU3989037.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VVK04_000333"
     CDS             complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VVK04_000333"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU3989038.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11219..11695)
                     /locus_tag="VVK04_000334"
     CDS             complement(11219..11695)
                     /locus_tag="VVK04_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU3989039.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VVK04_000335"
     CDS             complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VVK04_000335"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU3989040.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13063..13401)
                     /locus_tag="VVK04_000336"
     CDS             complement(13063..13401)
                     /locus_tag="VVK04_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU3989041.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13412..14515)
                     /locus_tag="VVK04_000337"
     CDS             complement(13412..14515)
                     /locus_tag="VVK04_000337"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU3989042.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMKIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VVK04_000338"
     CDS             complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VVK04_000338"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU3989043.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAKDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15701..16768)
                     /locus_tag="VVK04_000339"
     CDS             complement(15701..16768)
                     /locus_tag="VVK04_000339"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU3989044.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16787..17641)
                     /locus_tag="VVK04_000340"
     CDS             complement(16787..17641)
                     /locus_tag="VVK04_000340"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU3989045.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17631..18308)
                     /locus_tag="VVK04_000341"
     CDS             complement(17631..18308)
                     /locus_tag="VVK04_000341"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU3989046.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18305..19468)
                     /locus_tag="VVK04_000342"
     CDS             complement(18305..19468)
                     /locus_tag="VVK04_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU3989047.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20153..21787)
                     /locus_tag="VVK04_000343"
     CDS             complement(20153..21787)
                     /locus_tag="VVK04_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989048.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFTFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21768..22517)
                     /locus_tag="VVK04_000344"
     CDS             complement(21768..22517)
                     /locus_tag="VVK04_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989049.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            22696..24150
                     /locus_tag="VVK04_000345"
     CDS             22696..24150
                     /locus_tag="VVK04_000345"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU3989050.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIHDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLIELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRKDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDRANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24240..26858)
                     /gene="alaS"
                     /locus_tag="VVK04_000346"
     CDS             complement(24240..26858)
                     /gene="alaS"
                     /locus_tag="VVK04_000346"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU3989051.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(26880..27365)
                     /locus_tag="VVK04_000347"
     CDS             complement(26880..27365)
                     /locus_tag="VVK04_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU3989052.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27640..27879)
                     /locus_tag="VVK04_000348"
     CDS             complement(27640..27879)
                     /locus_tag="VVK04_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989053.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28124..29194)
                     /locus_tag="VVK04_000349"
     CDS             complement(28124..29194)
                     /locus_tag="VVK04_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU3989054.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29191..29964)
                     /locus_tag="VVK04_000350"
     CDS             complement(29191..29964)
                     /locus_tag="VVK04_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989055.1"
                     /translation="MKKFANLYLGLVFFVLYLPIFYLIGYAFNAGNDMNSFTGFSLSH
                     FKTMFGDGRLMLIVTQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLFSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29961..30767)
                     /locus_tag="VVK04_000351"
     CDS             complement(29961..30767)
                     /locus_tag="VVK04_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989056.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30748..31905)
                     /locus_tag="VVK04_000352"
     CDS             complement(30748..31905)
                     /locus_tag="VVK04_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989057.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32066..32971)
                     /gene="murB"
                     /locus_tag="VVK04_000353"
     CDS             complement(32066..32971)
                     /gene="murB"
                     /locus_tag="VVK04_000353"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU3989058.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33083..33835)
                     /locus_tag="VVK04_000354"
                     /pseudo
     CDS             complement(33083..33835)
                     /locus_tag="VVK04_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(33845..34576)
                     /gene="budA"
                     /locus_tag="VVK04_000355"
     CDS             complement(33845..34576)
                     /gene="budA"
                     /locus_tag="VVK04_000355"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU3989059.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELEERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVAIHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34718..35989
                     /locus_tag="VVK04_000356"
     CDS             34718..35989
                     /locus_tag="VVK04_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU3989060.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLKELERHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36009..36824)
                     /locus_tag="VVK04_000357"
     CDS             complement(36009..36824)
                     /locus_tag="VVK04_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU3989061.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(36981..37634)
                     /gene="phoU"
                     /locus_tag="VVK04_000358"
     CDS             complement(36981..37634)
                     /gene="phoU"
                     /locus_tag="VVK04_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU3989062.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37646..38404)
                     /gene="pstB"
                     /locus_tag="VVK04_000359"
     CDS             complement(37646..38404)
                     /gene="pstB"
                     /locus_tag="VVK04_000359"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU3989063.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38417..39220)
                     /gene="pstB"
                     /locus_tag="VVK04_000360"
     CDS             complement(38417..39220)
                     /gene="pstB"
                     /locus_tag="VVK04_000360"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU3989064.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39231..40115)
                     /gene="pstA"
                     /locus_tag="VVK04_000361"
     CDS             complement(39231..40115)
                     /gene="pstA"
                     /locus_tag="VVK04_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU3989065.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40105..41022)
                     /gene="pstC"
                     /locus_tag="VVK04_000362"
     CDS             complement(40105..41022)
                     /gene="pstC"
                     /locus_tag="VVK04_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU3989066.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41022..41900)
                     /gene="pstS"
                     /locus_tag="VVK04_000363"
     CDS             complement(41022..41900)
                     /gene="pstS"
                     /locus_tag="VVK04_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU3989067.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42474..43778)
                     /locus_tag="VVK04_000364"
     CDS             complement(42474..43778)
                     /locus_tag="VVK04_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU3989068.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AQLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43779..44552)
                     /locus_tag="VVK04_000365"
     CDS             complement(43779..44552)
                     /locus_tag="VVK04_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU3989069.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44542..44820)
                     /locus_tag="VVK04_000366"
     CDS             complement(44542..44820)
                     /locus_tag="VVK04_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU3989070.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44820..45221)
                     /locus_tag="VVK04_000367"
     CDS             complement(44820..45221)
                     /locus_tag="VVK04_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU3989071.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45431..46048)
                     /locus_tag="VVK04_000368"
     CDS             complement(45431..46048)
                     /locus_tag="VVK04_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU3989072.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46038..46811)
                     /locus_tag="VVK04_000369"
     CDS             complement(46038..46811)
                     /locus_tag="VVK04_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU3989073.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRGIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46822..47559)
                     /locus_tag="VVK04_000370"
     CDS             complement(46822..47559)
                     /locus_tag="VVK04_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU3989074.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSVVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47564..48694)
                     /locus_tag="VVK04_000371"
     CDS             complement(47564..48694)
                     /locus_tag="VVK04_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU3989075.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48778..49167)
                     /locus_tag="VVK04_000372"
     CDS             complement(48778..49167)
                     /locus_tag="VVK04_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU3989076.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49183..49566)
                     /locus_tag="VVK04_000373"
     CDS             complement(49183..49566)
                     /locus_tag="VVK04_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU3989077.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49567..50355)
                     /locus_tag="VVK04_000374"
     CDS             complement(49567..50355)
                     /locus_tag="VVK04_000374"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU3989078.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50348..51283)
                     /locus_tag="VVK04_000375"
     CDS             complement(50348..51283)
                     /locus_tag="VVK04_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU3989079.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51413..51589)
                     /locus_tag="VVK04_000376"
     CDS             complement(51413..51589)
                     /locus_tag="VVK04_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU3989080.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51729..52436)
                     /locus_tag="VVK04_000377"
     CDS             complement(51729..52436)
                     /locus_tag="VVK04_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU3989081.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52587..53615
                     /gene="queA"
                     /locus_tag="VVK04_000378"
     CDS             52587..53615
                     /gene="queA"
                     /locus_tag="VVK04_000378"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU3989082.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54277..54666)
                     /locus_tag="VVK04_000379"
     CDS             complement(54277..54666)
                     /locus_tag="VVK04_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU3989083.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54720..55412)
                     /locus_tag="VVK04_000380"
     CDS             complement(54720..55412)
                     /locus_tag="VVK04_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU3989084.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
     gene            complement(56127..56678)
                     /locus_tag="VVK04_000381"
     CDS             complement(56127..56678)
                     /locus_tag="VVK04_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989085.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(56973..57797)
                     /gene="nadE"
                     /locus_tag="VVK04_000382"
     CDS             complement(56973..57797)
                     /gene="nadE"
                     /locus_tag="VVK04_000382"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU3989086.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLTGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57794..59254)
                     /locus_tag="VVK04_000383"
     CDS             complement(57794..59254)
                     /locus_tag="VVK04_000383"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU3989087.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDDPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISYMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59370..59858)
                     /locus_tag="VVK04_000384"
     CDS             complement(59370..59858)
                     /locus_tag="VVK04_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989088.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59848..60057)
                     /locus_tag="VVK04_000385"
     CDS             complement(59848..60057)
                     /locus_tag="VVK04_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3989089.1"
                     /translation="MVKNLKLKLARVELDLTQGQLADAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60443..61171)
                     /locus_tag="VVK04_000386"
     CDS             complement(60443..61171)
                     /locus_tag="VVK04_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989090.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPDDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTIMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(61187..61978)
                     /locus_tag="VVK04_000387"
     CDS             complement(61187..61978)
                     /locus_tag="VVK04_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989091.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSTLMKILAQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
BASE COUNT        18640 a        14087 c        11473 g        18254 t
ORIGIN      
        1 acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc
      121 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
      181 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
      241 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
      301 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
      361 tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
      421 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
      481 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
      541 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
      601 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
      661 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
      721 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
      781 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
      841 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
      901 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
      961 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
     1021 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
     1081 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
     1141 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
     1201 caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt
     1261 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
     1321 agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
     1381 tggtttttga ccagcacctg gtccgtagta catagactca ccaataccga tagattctac
     1441 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
     1501 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
     1561 tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
     1621 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat
     1681 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
     1741 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
     1801 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
     1861 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
     1921 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
     1981 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
     2041 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
     2101 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
     2161 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattgatttt
     2221 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
     2281 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
     2341 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
     2401 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
     2461 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
     2521 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
     2581 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
     2641 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc
     2701 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
     2761 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
     2821 gatatcatcc ttggttttgt ctgcgatgct tttttccagg gttttgataa attcatctgg
     2881 agacatttga gctaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
     2941 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
     3001 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc
     3061 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
     3121 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
     3181 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
     3241 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
     3301 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcagctc ttagccgatt
     3361 ttgaagacct tatacatcag aatacttata atttaaagat tgctacacca aggatagaac
     3421 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
     3481 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
     3541 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
     3601 ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt
     3661 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
     3721 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
     3781 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
     3841 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
     3901 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
     3961 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
     4021 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
     4081 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
     4141 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
     4201 gattcaaaat cgttttggcc gaatcttctg gaggagtgat tttatagata agataagttg
     4261 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
     4321 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgt tttttataaa
     4381 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
     4441 agtaaatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
     4501 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
     4561 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
     4621 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
     4681 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
     4741 aggtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
     4801 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat agctcccaaa
     4861 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
     4921 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt cccttgttta
     4981 tagataaagt caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt
     5041 acataattga gtactcccat agctaacatg agaataggag aacctacaaa aatcgctaac
     5101 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
     5161 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
     5221 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
     5281 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
     5341 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
     5401 tcaaataatc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
     5461 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
     5521 ttcctagcta tgaagtagcg agccagaatg cctcctgtgg tcaagcccag aatcgaaacc
     5581 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
     5641 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
     5701 aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag
     5761 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
     5821 actagcgtca aggcataact gactatggtc aaactaaata ataatcgttt cccatcaatc
     5881 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
     5941 aatcgatata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
     6001 aaaattggat tcctagaaat agcaaaggca tggtctttta aaaaacgatg aatctgagaa
     6061 taggctttaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtgg
     6121 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
     6181 ttataaaact tttggtagat atcaatatag gctaaatcct tctctgcata gggtttggtc
     6241 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
     6301 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
     6361 aaggataggt cagttgcaat ctgtctcttg attagcttat tgcaaatcgt cccaggtatt
     6421 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
     6481 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagctcgaa
     6541 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
     6601 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
     6661 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
     6721 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
     6781 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
     6841 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
     6901 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
     6961 atcgacatca aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
     7021 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
     7081 gtccgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaaacc
     7141 ttcttgttta gacatagaca aaagaacttt cgtctgagat aaatactgat aaggattttt
     7201 ttgataacca aggaaatgta catagtcctc aatctcatac tctttgactc gttttttcag
     7261 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
     7321 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
     7381 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
     7441 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagcataat ctggataaac
     7501 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
     7561 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
     7621 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
     7681 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag ccagtcttgg
     7741 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
     7801 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
     7861 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
     7921 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
     7981 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
     8041 catgatgcgg tacctgcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
     8101 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggaaagaaaa
     8161 gattgtcttc aaaagatgtg attgggtact tgtttctcat gtagccagga cctgagcata
     8221 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
     8281 tccagatgcg ataacggaga gattttggag tcaaacccag taaaatgcga cttccccatt
     8341 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
     8401 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
     8461 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg
     8521 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaattcttg tgactctttg
     8581 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
     8641 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
     8701 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
     8761 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
     8821 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
     8881 cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc
     8941 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
     9001 ggtaactgac ttcgtcagtc ttatctataa cctcaaaact gtgtttttag cagcctgcgg
     9061 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
     9121 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
     9181 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
     9241 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
     9301 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
     9361 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc
     9421 atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc
     9481 gactttaatg gtttgggttg gagactcagt ctcggtagca tataaatcat ctccgactgt
     9541 agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc
     9601 agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt
     9661 aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc
     9721 ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccatt
     9781 aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt
     9841 cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac
     9901 actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc catctctagt
     9961 gtcctgacca ttaaagactt ctacttgagc tgcccgggca tcagcagttt tctttgcgct
    10021 agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag
    10081 tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg
    10141 gaaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc
    10201 aacctgctct tctctttctt gttccaagct agagctacta tttcccctag caagagttag
    10261 cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt gaatattttt
    10321 tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt
    10381 ctctcctttc catggtctga tattggataa ataggatagg cacccagaat tttatactgg
    10441 attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc
    10501 acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt
    10561 gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg
    10621 ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta
    10681 ggcttttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc
    10741 tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag
    10801 ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg
    10861 atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga
    10921 tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata
    10981 ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt
    11041 tcatgaacac taccctcaat agaattttca actggcacca cagaatagtc cactaatcct
    11101 tgctcataag ccttgatgac atctgtaatg ttggcaaaag cctgcaattc ctcatgagga
    11161 aaagctgtct gcacaacgtg gtgtgaaaat gatcctttgg gacctagata agcaattttc
    11221 atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag
    11281 ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat
    11341 tatttagaaa aagcggtcgc tgattgtcct tatcagctgc gatacgttgg tagagggttt
    11401 caaaatctgc tttcaggtaa atgttatctg tattagtctt gagtaagtca cgatttctct
    11461 gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta
    11521 ggacttctga ttctacctga cgaaaggctg attctccctt ttcagcgaaa aaattcgcaa
    11581 tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc
    11641 ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc
    11701 aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca
    11761 agctccacct ctccatctgc aaccaatagg gctgcgatag ctgtcatcat gccgatacgg
    11821 tggtcaccaa acgtattgac tctagcaccg tgaagagctg attttccttt gataatcatc
    11881 ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga
    11941 atacggtctg tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg
    12001 gcttgggtcg caagtagggc aataataggc aattcatcaa tcaaacgtgg aatcaaagcg
    12061 ccaccaatct ctgttccttt caagtcagaa gactcaacaa tcaaggttgc agatttagcg
    12121 actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata
    12181 ccggtgcgag tttcattgat ccccacattc tgcagcacta gacgagaatt tggaacaatc
    12241 aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac caccttctgt
    12301 cctgtcaatt tttgtggccc ttggactgtg attttcttac cgtccacact taaatgacca
    12361 ccaaattgtt tcaacatatc ttcagtatga ttacgggtgc actctttttc gataataact
    12421 gactccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg ggcagaggca
    12481 attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg aaggggaggc
    12541 aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg aagggtcaca
    12601 cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc gaaatctgca
    12661 ccagcaagga cacctgaaat caggcgaatc gaggtaccag aatttcccat attaagggca
    12721 ttttgtggcg cttttaagcc agccatgcct acaccttgaa tggtaataac cccatcttta
    12781 tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac gtcttcacct
    12841 cgcagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat aatggaacgg
    12901 tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg aatgtttgtt
    12961 tttagtttca tactggacct catacttgca atacttttac ctattttatc ataaaaagcc
    13021 agaaattcct taaaaattcc tgactttagg atcgttcttt tcttatttca gcaattctga
    13081 aactggttca aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt
    13141 ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc cttccatctt
    13201 agcttggaag gacgcatctg gcatttgacc tgtctgtgct agtttttgaa tttcctcttg
    13261 aaaggcaaga tattctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt
    13321 agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga gttcgtttgc
    13381 actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta tagtcggtat
    13441 tttctgttat gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta
    13501 ggattccgtg aatatcctca cgattttcct cgttgatgtg gatgttaacc aaggaagttc
    13561 cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg tcaacataga
    13621 ggtcgtaaga gctatccaca ccaccacgct tatggatttt catggtctgg cgttgttcac
    13681 gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa
    13741 tcgcttccaa acgttccttg aaatcctcaa ttctatccag aatgatctcg ctattggaca
    13801 agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac
    13861 cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca
    13921 tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct
    13981 ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct
    14041 taagcgtgtc ctgacttgtc agacttgaag gtgtaaagat ataataggca ttttcaaaaa
    14101 gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga
    14161 caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg
    14221 tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa
    14281 tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa
    14341 aactagcaaa atcatccgtt gcacggtcaa tcatgccttc tttcaaggcg atatctctcg
    14401 aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa
    14461 gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa
    14521 ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa
    14581 gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt
    14641 ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt
    14701 aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt
    14761 tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta
    14821 gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt
    14881 ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat
    14941 tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg
    15001 aaccaagacc aactggaacg cctccgacga ctgtctccac aaccccaccg atggtatcac
    15061 catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct tggttgacaa
    15121 tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa
    15181 catctatttc cttaccacca aagaccacga catggttggc aatctccata tccagctcag
    15241 ccaagaggcg tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg
    15301 aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg
    15361 catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct
    15421 tcgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag
    15481 gcgcccctgt cgtcttcccg tggcgaacgc ccgaagtaaa gacaacctgg tcactctcaa
    15541 tcttcatacg accaccacga ccgtagccac cctgacggcg tctaaggtcc tcattgatat
    15601 cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc
    15661 cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt
    15721 tcatctcttc cagagaaact gggtgaatga tcgctgaacc aagctctggc accaagacca
    15781 atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa
    15841 cttcccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt
    15901 gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc
    15961 ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat
    16021 ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa
    16081 ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa
    16141 tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca
    16201 agccatactt gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa
    16261 gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag
    16321 caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac
    16381 tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca aatccagcca
    16441 ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct
    16501 tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta
    16561 agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg
    16621 catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt
    16681 ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat
    16741 gatgaggaat atcgattctg attttcatag gagagtctcc ctttctttat tggtattttt
    16801 ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag
    16861 cttctgcagc ttgatagagc aacattccca gaccattgac tgctggattg ccctgacttc
    16921 tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca actaagagag
    16981 tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg
    17041 tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatactcta
    17101 aagcacacaa atccacttta aaacctgtct gctcctgtaa cttgtctagg taaggtcttg
    17161 ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag
    17221 cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg
    17281 aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta
    17341 aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctca
    17401 gcttatccaa ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca
    17461 tctggtagcg acgaatattg gccactgttt ctgccaagtc actcgcttca atctcccaag
    17521 ccacataagc accgttggta gctgtcgcct caaaggctct attgtggatg aagggagaaa
    17581 tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca
    17641 tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc
    17701 tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc
    17761 ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag
    17821 cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtgagccat caccgcaacc
    17881 ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt
    17941 gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa
    18001 acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagaa ttgcgcaact
    18061 tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga
    18121 gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc
    18181 tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg
    18241 tacctcgtgg catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt
    18301 aatttcattt actaaccttc atactaatca ccttgaggta attactactt tcatcttttt
    18361 tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg
    18421 caaagccttt atcaatttgt tctgtaaatt tctgacggga aacattggca gcattagtac
    18481 tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat
    18541 aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga
    18601 caatcacatc gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca
    18661 tgactataaa acgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca
    18721 attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg
    18781 cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca
    18841 agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaattcct gtcatcaagc
    18901 catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg
    18961 cttcttgacc ataaacatgg gcagattcat agtcaaaacc cttaaagcgg attttctcat
    19021 aagcccctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct
    19081 gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg tccactgtca
    19141 gacccccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc aaatcatctt
    19201 gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagtttgat
    19261 tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt
    19321 aggcagtccc aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat
    19381 tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa
    19441 cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc
    19501 tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt
    19561 cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccatcttgg
    19621 aggagcattt ctttttatca acgaaaatca aatagcaaac tatgaaacta gcctcaggtt
    19681 aaccgtgaga ttataggtag agaggttgta tcagcaatat gtgtctgtca aatttagtga
    19741 caaaggtagt agaagaaaga tgaagaaata aatcagcttc agtagatatc tggaaaattt
    19801 gattttatag aaaagccttt tgttacaaac tcaatatact atcaataaat aatattatag
    19861 aagcaacaat aattaaaatt tcacctattt gcatcattct atttcgaact ctaaatatat
    19921 gttctatcaa aaatacttgg atcacacaca ttataggaat taacgttttt gaaattgaaa
    19981 aatatcccaa taaataaact ataaacaaca ataatagaac tatattatat ttcttattca
    20041 aaacattcct ccctatattt ttgattacca atcttaatca tttacaacta cattctaaca
    20101 aactataaaa gcgtttgtcg aattgaattt atcaagcaag caaccaacta tctcatcttt
    20161 tttctatttc tgccaatatg cgtgacaggt aataatgata gccaaaaata gcaagagcaa
    20221 gcaagacgat aagagctcct actcccaagt tgatggcaag gataggggag agagactgaa
    20281 ccaagaatat gctcccaatt acaagggcca tcaggattgc actataaata aacaataaaa
    20341 ctatggcgac tatgccattt gaacgattca ccaggtccgt aatgctactc caattggttg
    20401 acagattttt aacgtcctta aagtaatggt ggcaagaaag gatgacactg gcaatgatcc
    20461 agactacaag aaggtaaatc atcgaaagga tggacaagcc tagatataga gaaagaccga
    20521 gcaaagtcag aactggtaaa aaggactgaa cagcaaagat aatccaaaat ttcactttca
    20581 cataacgagc aaagtcaaag ggtaaactct tcagaaaatc aacattttcc ctctccaagg
    20641 acaaggcaat tgaatgcagg ctggtgatat tgttattgac aactgctata aacactccta
    20701 caaaaaacaa gggtaaccag tatggaggat gaatgtctgg aactatctga gaatctcgga
    20761 ttttggaaat cagactgatc atcatgagat aaggaaggaa agcacttgta aaaagcactg
    20821 taaccacacc agtcccctgt cccaagaggg tgaggtggta gcgtaaaacc atacggaaaa
    20881 agcccttttt agtagttgaa atcctctcct tgctgcgacg ttctttctta accttctcct
    20941 cactattaag caggatcacg tcataaaaac gaggaaggac cttctttttg gtcagataaa
    21001 gcaggaagag agttagtcct atccaagcga gcagacccac taaggcttct attgaaaaag
    21061 gctccactgc tattttgtaa aagatatgaa gaggataaag gagaaatgga atgtctctaa
    21121 ctttgtcaac aatacttcca aaagtcgact gaagaaagaa ggtaaatatt aaaggtatga
    21181 gaactcctat cccaatcatc acattcgaaa aaatagactg atactttctg aagaccctag
    21241 tctgagccaa gaaatgtact gccactaccg tcactaaagt aacagagaca aataataagg
    21301 tcaaggacag tagcatcaaa ggcaaaccca gccaaagaga aggagctaga ctaatataga
    21361 gggctagaaa ataagctagg attggtacaa ttccagttag agctggcaag aggacagaca
    21421 gacctttggc cattataatc tctgattctt taaaggcata gggcctatag gaggccaggt
    21481 ccttactctc ataaaagaca ttgtaaaagg cagtgaaaga agttgaaaag gccagcacca
    21541 gtaaaatagc aaccatcgag ctaaaataaa taggcatttc ctcaaaagga aaatgaatgg
    21601 ctatattact aaaacagatg agcatcaaga gactggaaaa aatgtaagaa cttaggactc
    21661 tagcggaaac atttactttt tttccagtat ttttagcttg cttctttcgt aggttagcca
    21721 gattagcttc ttgagatgaa tagaggatat tgatatcaac taatttttta atgaccttga
    21781 gacgcatctg aaacctcctc ttttctacca gcaaggctaa ggtagatact ttccaaagac
    21841 tggtctgggt tgtcttttct caagtcctct accttaccac aataaatcaa atgccccttt
    21901 ttcaaaatag caatccgatc acagacttgc tcagctacct ctagcacatg agttgaaaac
    21961 aaaactgtct tacctttttg cgcatgctcc ttcatcattt gcttcaaatc aaaggcggcc
    22021 tggggatcca aaccagtcaa gggttcatcc aagacccaaa tatcgggatc agacaagagt
    22081 gctccgatga caaagacttt ctgacgcatt ccgtgagaaa gagtttcaat aacctgatag
    22141 cgattttcag caaaatcaaa aacgttcaat agcctagcta gactagcctc caagtcagat
    22201 ctactcagat cataggatga ggcgatcaat tcccaaaatt cattggccgt taagcgtaaa
    22261 aataagtcag gcgagtctgc tacgtagcca atctttcgtt taatagccaa gcgattttcc
    22321 gataactcct gaccgtctac caaaatacga ccactgctgg gtgaaatgat actgactagg
    22381 gattttatag tggtcgattt tccagcccca ttatgaccaa tcaagcccat aatctctcca
    22441 ttttcaatct gcaaattgag attactcaag gcctctttat caccatacaa cttactaaca
    22501 ttttgaaatt caatcatggg acaactccta tctttatctg tattatacat cgctatacta
    22561 gcactttgat acaaaaaaat caatacttta ttttaagtag ttaaaatagt ttccttctat
    22621 cttacgcaaa cgtttgcgct aatagatact ttatgataga ataaagaaca agattgacaa
    22681 gtaagaggaa acattatgca aaatcaaaca ctcatgcaat actttgaatg gtatctgccc
    22741 cacgatggtc aacactggac gcgtctggct gaaaatgctc cacacctagc tcatctgggg
    22801 atcagtcacg tctggatgcc accagccttc aaggcaacca acgaaaaaga tgtcggctat
    22861 ggggtctatg acttatttga cttaggagag ttcaaccaaa aagggactgt ccgcaccaag
    22921 tatggtttca aagaagacta tcttcaagcc attcaagccc ttaaagcgca gggaattcaa
    22981 cctatggccg atgtagttct caaccacaag gctgctgctg atcacaggga agcctttcag
    23041 gttattgaag tggatcctgt agaccgtaca gttgaacttg gagaaccctt caccatcaat
    23101 ggctggacta gttttacctt cgatggtcgc caagatacct acaatgactt ccactggcac
    23161 tggtaccact tcacaggtac agactatgat gccaaacgcc gtaaatccgg gatttaccta
    23221 atccaaggag acaacaaggg ctgggctaac gaggaattgg tcgataacga aaacggaaac
    23281 tacgactacc tcatgtatgc cgacctagac tttaaacatc ctgaagtcat ccaaaacatc
    23341 tatgactggg ctgattggtt catggaaacg actggtgtag ctggtttccg tttggatgcc
    23401 gttaagcata ttgactcttt ctttatgcgc aatttcatcc acgatatgaa ggaaaaatac
    23461 ggtgacgatt tctatgtttt tggtgaattt tggaatccag acaaggaagc caatctggac
    23521 tatctcgaaa aaacggaaga acactttgac cttgtcgatg ttcgtctcca ccagaatctc
    23581 tttgaagcca gtcaagctgg cgcaaactat gaccttcgtg gcattttcac agatagcctg
    23641 attgaactca agcctgacaa ggctgtgact tttgtcgaca atcacgatac ccaacgagga
    23701 caagcccttg agtctaccgt tgaagaatgg ttcaagccag cagcctatgc cctcattttg
    23761 ttacgcaaag acggccttcc atgtgtcttt tacggagact actatgggat ttcagggcag
    23821 tatgctcaac aagatttcaa agaaatcctt gaccgcctcc tagccatccg aaaagatttg
    23881 gcctatggag aacaaaatga ctactttgac cgtgctaact gtatcggttg ggtacgttca
    23941 ggtgctgaaa atcaatcccc aatcgcagtc cttatctcaa atgaccaaga aaacagcaag
    24001 tcaatgtttg tcggtcaaga atggactaat caaacctttg tagatttact tggtaaccac
    24061 caaggtcaag ttacaattga tgaggaaggt tatggacaat tccctgtctc agctagatcc
    24121 gtaagtgtct gggcagtcaa taccatctaa tagctcataa taaccaagct aggtccaagc
    24181 ggatttggct tttttgtatt cacaaaaaga cctacccaaa tggatagatc tttacttgat
    24241 tacaatttac ctgctactgc atccaacaat tcttggatct tagcttggtt acttcctcct
    24301 gccatggcca tgtctggttt accaccacca cgtccatcga tgattggtgc taattctttg
    24361 acaaggtttc ctgcatgaag gtcttttgtc ttgcttgcta caaggacatt gactttgtca
    24421 ccgatagcgg caactaggac aagaagatca gagtagtctt tttgtttcca gttatctgca
    24481 aaggtacgaa gggcacctgc atcggataca gacacttgac tagcaatgta acgatgaccg
    24541 ttgacttcct taacatcttt gaagatatcg cctgcggctg cagctgcggc tttttctttc
    24601 aactcagcat tttctttttg aagttgacga agttgttctt gaagtccttc taccttgtga
    24661 ggtacttcct tgacttgagg tgctttcaag gttgctgcga cagctttaag agcatcctct
    24721 tgttcacgat aggcttcaaa ggcttcctta ccagtcactg ccaagatacg gcgagttcct
    24781 gaaccgattc cttcttcttt gacaattttg aagagaccaa tctcagaagt gttgccaaca
    24841 tgagtaccac cacaaagttc aatagagtag tcaccaatag tcacgacacg aacttccttg
    24901 ccgtatttct caccaaagag ggccatagct cccatttctt tagcagtgtc aatatccgtt
    24961 tcaactgtct taacttcaag agcttcccag attttttcgt tgacttgctg ttcaatcgca
    25021 cgcaattctt cagcagttac agcttggaag tgggtaaagt caaagcgaag gaattcaact
    25081 tcgttaagag atcctgcctg tgttgcgtgg tttccaagga tattgtgaag ggcagcgtga
    25141 agcaaatgag tcgcagtgtg gtttttcatg acacggtgac ggcgattgct atcaattgcc
    25201 aaggtatatt cttggttcaa ggcaagcggt gcaaggactt caactgtatg aagggcttga
    25261 ccatttgggg ctttctgaac attggtcaca gtagccacaa ccttacctga ctcatccaag
    25321 atttgtccgt ggtcagcgac ctgtccaccc atttcagcat agaatggcgt ttccgcaaag
    25381 ataagtgagg tagttccttc tgatacagct tctacttctg cattgtccgc cacgatagct
    25441 accaatttag aagacaattg gctagcattg tggttgaaga cactttctac agtgatgttt
    25501 tgaagagttt cattttgcat acccattgag ccacccttga cagctgacgc acgcgcgcgt
    25561 tcttgttgtt ctttcatggc tgcttcaaaa ccttcacggt ctacagtcat accagcctct
    25621 tcagcaattt cttcagtcaa ttcaactggg aatccgtatg tatcatagag tttaaagaca
    25681 tcttgaccag caatgacaga ttgacctttt tctttcaagt ctgccacaat gccttgggca
    25741 aagtgttgac ctgagtgaag ggtacgggca aatgattctt cttcgctctt aacgattttc
    25801 tcaataaagt cacgtttctc aagcacttct gggtagtagc tttccatgat ttttccaaca
    25861 gttggaacga gtttgtaaag gaaaggctcg ttgataccca atttttgacc atgcatagaa
    25921 gcacgacgga gaagacgacg aagaacataa ccacgacctt catttcctgg aagggcacca
    25981 tcaccgatgg caaatgaaag tgaacggatg tggtcagcga tgaccttgaa gctcatgttg
    26041 tcgccatctt ggtcataaac cttaccagac aatttctcga cttcacggat aatcggcatg
    26101 aagaggtccg tttcaaagtt ggtcttagcc ccttggataa cggccaccaa acgctccaaa
    26161 ccagcgcccg tatcaatgtt cttatgtggc aattccttgt attcgctacg aggaacagca
    26221 gggtctgcgt taaattgtga caaaacgatg ttccagattt caatataacg gtcgttttca
    26281 atatcttctg caagcaggcg aagaccgata ttttctgggt caaaggcttc cccacggtca
    26341 aagaagattt ctgtatctgg tccagaaggt cccgcaccga tttcccagaa gttgtcctca
    26401 attggaatca agtgacttgg atccactccc acttcaatcc agcggttgta agaatcttta
    26461 tcgtctggat agtaggtcat gtaaagtttt tcagcaggga aatcaaacca ttcagggctt
    26521 gtcaaaagct cataagccca agtgatagct tcgtcacgga agtaatcccc gatagagaag
    26581 ttccccaaca tttcaaacat ggtatggtga cgcgcagtct tccctacgtt ttcgatgtcg
    26641 ttggtacgga tagccttttg ggcattggta atacgtggat tctcagggat aatggtcccg
    26701 tcaaagtatt tcttgagggt tgctacccca gagttgatcc acaaaagagt tgggtcgttt
    26761 acaggaacca aacttactga tggttctact gagtgacctt tggtcgccca gaaatcaagc
    26821 cacatttggc gtacttgtgc actagatagt tgtttcatat tgtctcctta tttacttgtt
    26881 taatgtgatt ggctttccag catttccaca tagtcaatcg cgacacagag ggaaatgact
    26941 aggtctgcat aagcgtcctc aagaaccgtt acggtatagg tagaggtcag atggaagagt
    27001 tccttcttaa tttccgcaat cagctgatcg cgatcatcca gcaatttgaa attcaaatcc
    27061 cagatattgc cctcgatacg aagacctaga ttatcaaact catacttatc tcgccagaag
    27121 gtcaacttct tacgaatgac aaaactcgag ccatcccgaa gctgaatctc aaaacgagga
    27181 agcaaggtca agatttcttt actaatctca ctgacttgtt caccagccgc atcatagatg
    27241 gtaaaggttt taggaatctt aaaaaatgat ccctccacct gataggcaat ttctcccctg
    27301 tcatccttga tagcgaagcg ttcgcctcca agacgaaact tttgtttgac aagaaatgtt
    27361 ttcatcaaca cctccaaaaa tcaaaagaca agctcatatc acgaagggcg aaaaaccgcg
    27421 gtaccacctt cattcaatga acttgtcatt ctcttgttct tatgcaattg tatgattgag
    27481 tagcatgact tcctagctta gatggctcgc agcaccgcca tttctctgga ctaagacaag
    27541 tgaaaatcaa ttctcaactt tcttattata acgttttttt aagcttgcgt caactggaaa
    27601 tgatctccgt tgaattagac caattcccta catctctgat tactttttca ggatatattt
    27661 tttcttactg ccgtttttct ttttatccca aattttcata ttactaaaca cagctactag
    27721 aatatttcca aatataaagg tgcctatcac ccaatatatg gactcagttg ttaggtattg
    27781 tcgatccaag ccatccttta aatgggatag tataacagtt tggttaacaa tcataaaggt
    27841 tggccagaaa ctttttttga aaaaagtaga cattttcatt atttgttgcc gctttctgta
    27901 aggttaatac tcaataaaaa tcaaaaagca aactaggaag ttagcctcaa gctgtacttg
    27961 agtacggcaa ggcaacgctg acgtggtttg aagaatatag gcttagtata ctactaggca
    28021 agcaaataag caactagaat agaaaaagat agggttctaa aaactgactt ctattcctta
    28081 aaaacgaacc agcttgactg attcgtcttc ttacgtttat ctcctacttc cgatacattt
    28141 taaactgtag gaagaggtcg ctatatttcc ctgtccattt atggtcaaat ttctcataaa
    28201 cttctaggtg tttcatggtt tcaacatctg gatagaaggc cttatcttcc tttgtttcct
    28261 ctgggagcaa ttccttcgct ggtaggtttg gtgttgaata gccgacatac tccgcatttt
    28321 ggagagcatt ttcaggtttc aacataaagt tgataaaggc ataggctgag ttttggtttt
    28381 taactgtttt gggaatgacc atattgtcaa accaaagatt gctggcctct gtcggtacca
    28441 cataacgtag attttcattt ttttctaaca tttggctggc ttcaccagag aaggtcacgc
    28501 cgattgcaac attattctga atcatatagc ccttcatctc gtccgcaacg atagccttga
    28561 tatttggagt cagtttgtag agcttatcca ctgtctcttc caactgctgc agatccttgg
    28621 agttgaggct gtagccgagg gaattgagtc ctagtcccag cacctcacgc gccccatcaa
    28681 agagcatgat agaattctta tactccggct tccaaaggtc atcccaatgc tcaggcgctt
    28741 catctaccat ggtttcgttg tagacaattc ctaaggttcc ccagaagtaa gggatggaga
    28801 atttattacc tgggtcaaag gactggttga gaaactctgg tccgatattt tcgattcctt
    28861 caatttttga ataatcaagc ggaaccaaga ggtcttcgtc cttcatcttg ttaatcatgt
    28921 attcacttgg aatggcaata tcgtaggtcg ttccaccctg ctttatctta gtgtacatgg
    28981 cttcgttgga gtcaaaagtc tcgtactgaa cttgaattcc tgtttcttct gtaaactgag
    29041 tcaagagttc aggatcgata tagtctcccc agttatagat aaccaatttt tgactatctc
    29101 gactattgat tttactatct aaatgagtcg caattcccca caagacaagg ataatcgctg
    29161 caattcctgc taaaaatgaa tagatttttt tcatgcttgc tcctccttct cacgagagat
    29221 aaagtaataa cctacaacta ggataatact aaagagaaag actagagcag acagggcatt
    29281 gatttctaag gaaatcccct tgcgagcacg agagtaaatc tcgactgata gggttgaaaa
    29341 gccatttcct gttacaaaga aggtcacggc aaaatcatcc agcgaatagg tgaaggccat
    29401 gaagtaacct gcaatgatag acggagtcag gtaaggaagc atgatttcct tgaacatctg
    29461 aaattgacta gctcccaagt cataggccgc atgaatcata tcgccgttca tttccttgag
    29521 acgtggcaag accatcaaga caacgatagg aatggagaag gccacgtgac taaatagaac
    29581 ggtcaaaaag ccaagtgaaa acttgagttg ggtaaagaga atcaagaaac tagcaccaat
    29641 cataacgtca ggcgcaacca tgaggatatt attgagtgat agaaaggctt cttggtattt
    29701 cttacgagac tggtagatgt aaatggcacc aaaagtcccg ataatggtcg ctatcaaggc
    29761 tgataggaag gccaagaaaa aggtctgagt cacaattaac ataaggcgac catcaccaaa
    29821 catggtttta aaatggctca agctaaagcc tgtaaagctg ttcatgtcgt ttcctgcatt
    29881 aaaggcgtag ccaatcaagt aaaaaatcgg caggtagagg acaaaaaaga ccagtcccag
    29941 ataaaggttg gcaaattttt tcatcgttct ctcctttcct tggtcaccca catggtgatg
    30001 aacatggtca agatgagaat tacaccgatg gttgaaccca taccgtagtt gtcattggtt
    30061 aggaaattct gttcaatagc cgttcccagc gtaataacac ggtttccacc aatcaaacgg
    30121 gtcagcatga agagactcaa gctggggata aagacagatt ggaccccact tctcactccg
    30181 ttcatagaca gagggaagat gacatgacgg aaagtctccc acttggtcgc acctaggtca
    30241 tagctggcat tgatgagatt gttatccata tcgtccaaga cattgaaaat cggcaaaatc
    30301 ataaagggaa gctcgatgta gcttgcaaca aagataaagg agaaatcggt aaaaagcaac
    30361 tgctgtgaac caattccgat aaattccaag aattggttaa tagagccatt ctgaccaaaa
    30421 atcccgataa aggcataagc cttaagaaga aggttgatcc aagttggcag aataatcagc
    30481 ataatccaga gttgacggtg tttgagacgg gtcaaaaaga gggccgtcgg ataactgata
    30541 agcagtgtca caaaggtcac aatgcctgca taaagcactg agttgaaact cattttaaga
    30601 taggtcaagt tttgtgacgc aaagtaagat ttgtaatttt ctaaactgaa ctggccttcg
    30661 atattgaaaa aggattgacc gaaaatcaag accaagggtg ccaatacaaa gagcgcaatc
    30721 caaagcatgt agggcactac aaagagttta gagcttgttt tcttcatctc tttcctcctc
    30781 gattgcattg atcaaacctg cttcttgctc ttcgatttct acgtactcct caatacgagc
    30841 atcgaactct tcttcggttt cattgagacg catgatgtgg atgtcttctg gttcaaagtc
    30901 cagaccgatt tcctcaccca cgatagcctt acgggttgag tggatcatcc attcatttcc
    30961 aagttcgtca taagcgataa tttcataatg aactccacgg aagagctggg tatcgacctt
    31021 aacttggagc ttgccttctt caggaagggt aatgcgcaag tcctctggac gaataacgac
    31081 ctcaacaggt tcatttggct tcatcccacc atcaaccgct tcaaagcgtt tgccgttaaa
    31141 ttcgaccaag tagtcctcaa tcatggtacc tggcaagatg tttgactccc cgataaaggt
    31201 ggcaacaaag tggttgattg gctcatcgta gatgtccaca ggggttccag actggacaat
    31261 ctcgccatca ttcataacga aaatccagtc actcatggca agagcttctt cctgatcgtg
    31321 agtgacaaag acaaaggtaa tgcccaatcg ttgttgtaat tcacgcaatt cgtactgcat
    31381 gtctgttctc aatttcaagt ccagcgctga taaaggctcg tccaacaaga ccacacgggg
    31441 ttggttgatg atagcacggg cgatggccac acgctgacgt tgtcctccag aaagtttgcg
    31501 gatggaacgt ttttcataac cttccaactg aaccatcttg agaacttccg ctacacgctg
    31561 ctcgatttct ttcttatcaa ttttacgcaa gcgaagtgga aaggcaacat tttcaaacac
    31621 attcatatgt gggaacaagg cataggattg gaagacggta tgtacgtcgc gcttgttggt
    31681 tggaatatca ttgatacgaa caccgtctag catgatatct cctgtcgtcg catccagtaa
    31741 acctgcaata atgtttagga tagttgattt ccccgaacca gatgcaccta gaagggtgta
    31801 gaatttccct tcttccaact caaagttgat gtctttgaga accttggtgt tgctgtcttc
    31861 aaaaacttta gagacgtttt tgaattcgat aattggtttt ttcaattggc ataaattcct
    31921 tctttttcat agattaacag atcggggctc tgtcaggtcg ccactacctc ttgcagggag
    31981 taaaaccacc tgcatacatc ttcgctaccg ataggctttc accccccttt ccatgacata
    32041 gcagcagctt ttcaaataca gcttcctact tgctttcacc caagatccgg acttctcttt
    32101 caagcgtaat acctgagtgt tccttgactt tttcgataac cgattggatc aagtcctcgt
    32161 agtctttggc cgttccatct gcgacattga tcataaatcc tgcatgcttt tctgacactt
    32221 ctacgccacc gatacgatag cctttcaagc cagcttctga aattaactga cctgcaaaat
    32281 gcccgactgg acgcttaaag accgagccac aagatgggta ttccaaaggt tgcttgagtt
    32341 cacgtaggtg cgtcaagcgg tccatttcct gcttgataac ctgatgggtt cctggagcta
    32401 gggcaaattt aactgacaag acaactgcac cagactcctg aatagctgaa tggcggtaac
    32461 caaaagccaa gtctttagca gacagggttt cgatttctcc atccttggtc aagaccttac
    32521 aagactgcaa gatgtgagca atctcgccac cataggcacc cgcattcata aagacagcac
    32581 cgccaacgct tcctggaata ccacaagcaa actcaaagcc agttaaacta tgacggaggg
    32641 caatgcgagt tgtttcaatc aagttagccc cagcttctgc ttcaatggta tagccatcaa
    32701 cagaaacgtt attgagcttg tcacacaaga tgacaaatcc acgaatccca ccatcacgaa
    32761 cgataatatt gcttgcattg ccaagaacca tccaagggat attttcttgg ttggcaaatt
    32821 tcacaaggcg cgccaactca aaacgatttc gtggaaagac caaataatca gcctctccac
    32881 ctacttttgt ataactatag ctatgcaagg gttccttaaa acggatatca attccttcta
    32941 agatttcaag cattttttct cttacagaca tgtcactctt ccttttacaa aattcattcc
    33001 attataccat ttttagagac atttgacgac cataaaaata ccttgtttgg attttgcata
    33061 agaaaaagag gttcccccct ttttatgatt ttttacaaaa gatttccttg gttccatagg
    33121 cgaccagaac gagctccagt gctagaatca cttcaaccaa gactggattt gtcaaccagc
    33181 ctacttggaa aagagatggt gccagatcaa agaaggcatg caagccatag gctgttagga
    33241 gataaatcca tttcttctgg cgaacagctt ggtaaaccca aactgtcaaa agtaattgga
    33301 aaccaagcgc caagattcgc tcaaaaccaa gcaaataaat ctgccagacc gaaagtgact
    33361 gaatggtttt taacatattt tcagacagta attgcataac ctgtggattc tgagtttgaa
    33421 ctgccgaaag aacaatgtaa agattgagta aactagtaag gcctagaaaa atcaactcca
    33481 agccaccatg ccccagtcca taggccaagg cgtctgcctt ttccaaactt ctctttttct
    33541 tcaaccattt gaagaaaaca agacgagccg tttcctcaaa aaatgctgcc atggctaggc
    33601 catagataat atagacaagc ggatgatctt gcaagagggc aatactaccg tctttttgag
    33661 gatgcaaaat caagatatgc accagttttt ccaaaatctg cgaagagaca aagaaagcga
    33721 ctgcacccaa gcccaagaca gctagattaa tctggtattt ctttttggca aatcaaatgc
    33781 ttcctatcag aaaagctagc aacagcaaca tggtaataat gatatgaatg gtcattttct
    33841 tctcctattc tgccttttca atatcttttt tcatctcgtc aacattgaac ttagcaaaca
    33901 agtattgacg gtcttggact gggaaacgtt ggtccaactg gtcaactgct cccacctcga
    33961 taatgccttc cttgatgaca aaatccatga catgtccacc gaaggtcaaa tcatctgata
    34021 tgaagtgcag atggtagcct gccacactga ccccatggaa aatctcaggc gtccagaaac
    34081 caacaatagt ccccgcaaca ttgtcacgac tatattccgg ttgatggatt gcgacatcag
    34141 caaacttggt atcgggtgtt gacttaggaa tcatacgcac atgcatatgt aaaaattccc
    34201 cccgaatctt gatagagcgg aaaagatttt ccccatcata ataagactca attcgttctt
    34261 ccaattcctt gtctgtcatc tcaaagcgct gacggaaaat gacctctgcc tgatgcggta
    34321 ctactgctgc ataaggaata agggcatctg gtgacacttc cacaatttct ggctggtctc
    34381 ctgacccttt ggcctgataa gccttgccat ccaagacaat caattcccca tcaatggaat
    34441 ccaaggttcc caaaccaagg tcaccatgtt ctagcaattc tcctactgtc atagtaccac
    34501 cataaaggcc agccatcaag gctccaagag tattgtattg aaataatttc actggttcct
    34561 gcacgttctt atccattcac tttcttgtct gttattctat aaatcttact cctaagtata
    34621 ccacatttac ccctagatgt gaacgagaga aacgctctag acattgccaa gaaggaaaaa
    34681 aaaaggtaca atgtaacaaa atcaagggag gtctggaatg aagaaacaaa gcaagtacaa
    34741 agaggtcgtt tcctatctga aaaatggtat cgagtctgga cgatttccga cgggaagtcg
    34801 cctgccttct atccgtcaac tgagccttga cttccactgt agcaaggaca ccattcaacg
    34861 agccctgctg gaattacggc acgaacaata cctctatgcc aagccccaga gtggctacta
    34921 tgtcctagaa caagggcaac accaggacct agaaatcgag gttaccgacg aacatgccag
    34981 tgcctatgac gatttccgac tctgtgtcaa tgaaaccttg attggccgag aaaactacct
    35041 cttcaactac tatgacaatc aagaaggatt agaagaccta agacaatcca ttcacaaact
    35101 cctctttgag caagctctct actgcaaggc taaccaacta gtactgactt ctggaaccca
    35161 acaagccttg tttatcctct ctcaaatatc ctttcctagc caagccaagg aaatcttggt
    35221 ggaacagcca acctaccatc ggatgaatcg cctcttgatt gcacaggggc tggactatca
    35281 aacgattgaa cgaggcattg atgggattga cctgaaggag ctggagcgac acttcaagac
    35341 aggaaaaatt aagtttttct acaccattcc ccgatttcac tatcctctgg gacattccta
    35401 ttctgagcaa gacaaacgat ccattcttaa cttagctgcc aagtatgatg tctatatcgt
    35461 agaagacgat tatctgggtg atttggactc caagaagggc caaaccttcc actatcttga
    35521 tacagaggag catgtcattt atatcaagtc cttctcgacc agcctttttc ctgcccttcg
    35581 tattacagca ctcattcttc caaatgctat caaagaagca tttgtggcct acaaaaatat
    35641 cctagactac gacagcaacc tcattatgca aaaggccctg tcactctata ttgacagtca
    35701 attgtttgaa aaaaatcgtt tggctcgctt gaccaatcat gaatcttacc aaaaacaaat
    35761 cgaggaaagg ataactaaaa caccttgtcc ccttcctcat tatcccctac acgatggttt
    35821 attgctagac ctgagacagt atcctaaaat cgccagtctc aaacacagtc aaccgggctt
    35881 ggacttcttt gaagaggcct atttaagtac ctgtccttat caatttgcca aggtgtccct
    35941 agacaatctg gaaaatgttt taaactattt aaaagcagaa ttggaatgac atccaactct
    36001 gctttttctt attcttcaac ttcagttaga cttgctgctt tttcaagata gctttggtaa
    36061 attccttcat ccttaagttt ttggatgacc ttgtctacca cttctttcaa atcatcacta
    36121 ttttttctaa gagcaacggc attggcgtcg ccatccttca tcttcaagct gacagttgcg
    36181 acagctaagc cagcgttttt agcagcataa ctaagtgcaa caggctcatc catatgaaca
    36241 gcatctactt ttccagcctg caattcattg actgcttcac ccatattagt tagggaagtt
    36301 aattgagctt ttggcaattg ttccttgacc attgattctg gaacagtccc tttttgggct
    36361 gcaatattag cactttctag gctagttaaa tccttgtatt tttccacatc agccttacga
    36421 accaagaaac taatcttgtt ttcatagtat gggattgaaa aatcaaagac ttcttttctc
    36481 tcgtcagtag cactaattcc tgcaactgct aggtcagcct taccagtttg aagactggtc
    36541 aaaacattgt caaaactcat gcttgagatt tccaacttaa ccccaagttc atcagcgata
    36601 gcctgagcca tgtcgatgtc tgcaccgact acctggttct ttccatcaac caatgattga
    36661 aattcaaagg gtgcatagtc aggactggtt gccacaacta attttccctt ttgcttaatg
    36721 gcctcaacag ctgactgaga accattagaa cctgactggc aagctactaa gaagaaactt
    36781 gcaagaaaat tacataaaac aaatatccat ttttttgatt tcataaataa acaacctttc
    36841 tgttaatttt gtataattat aacgatatcc aagttacttg tcaagtgttt tttaaatttt
    36901 tatctcaaaa atattttttc gttcaaaaaa aggagccatc agttgatttc aagctccttt
    36961 ttatacagaa ttaaactatt ttatagttcg acaatcttac ctgtttcaaa gtagacaacc
    37021 cattcacaga tatttttagc atagtcaccg atacgctcca agtaggaaat aacttggaaa
    37081 taatcacgac ccgtaacaat ggcttctgga tttttcttaa tctcttcagt cgcaaggtca
    37141 cggatagttt caaaatagtg gttaatttgc tcatccatgg aggccacccg gtatgcgtcg
    37201 tcaacagaac cattaagata aagatcaagt gctgcttcaa caacgctttt aacttcacgt
    37261 cccatttttt taatttcttc ctctacagct gggatgcgtt cttccccctt catacggatg
    37321 gttgcctggg caatggctac agcgtgatcc cccatacgct ccacatctga tacagcctta
    37381 aggacagtca agactgtacg caaatcttga gagactggtt gttggagtgc gatcatttca
    37441 aatgatttct tttccagttt cacttcgtat tcatttactt ctgcatcatc ttctatgacc
    37501 tcttttgcca ggtcacggtc atgcgtgaca aaagcacgta ccgtacgatt gatttgtgag
    37561 agcacttctt gtcccatagc gtagaactgg ttatgtaatt tctctaaatc ttcttcaaat
    37621 tgagatcgta acatctttca tctccttatc caaattttcc tgtaatatag tcttccgttt
    37681 ccttgtgttg gggatcaagg aacatctgct tggtatcatt aaattcaatc aaatctccat
    37741 ctaggaaaaa tcctgtctta tcagagatac gtgaagcttg ctgcatggaa cgggttacca
    37801 gaagcatggt gtacttgtct tttagaccat acaaggtttc ctcaatttta ccagctgaaa
    37861 tcggatccaa agccgaagtt ggctcatcca agaggatgat tttaggacta gttgccaaga
    37921 cacgggccac gcagacacgc tgctgttgac cacctgacaa tccaatagct gaatcatata
    37981 gacgatcctt gacctcatcc cagatagagg caccttgcaa ggctttttct acggcttcat
    38041 ccagaacctg cttatcctta attccattga tacgaagccc gtagacaaca ttctcataga
    38101 tagtcatagg gaaaggatta ggttgttgga aaaccattcc gatttcctta cgtaattcaa
    38161 ccgtatctgt acgcggactg tagatgttgt gaccattgta caccacggat ccagttgtgg
    38221 tcacctctgg attgagatct cccatgcggt tgagagactt gaggagggtt gacttccctg
    38281 atccagatgg accaatcaag gctgtaattt ccttaggttg gaaagatagg gaaacactat
    38341 tcaaagcctt ctttttatta taataaacgg acaggtctga tacctgtaaa atcgcatctg
    38401 tcatacggtt tcctttctaa ccaaagtgac cagatacata gtcattggtg gactgtagct
    38461 tggcattttg gaaaatagtt gcagtcttgt catactcaat caaatcaccc aagtaaaaga
    38521 agcctgtata gtcacttgca cgagcagcct gctgcatatt atgcgttaca atgatgatgg
    38581 taaagttttt cttgagctca aacatggtct cttctagttg catggtcgca atcggatcca
    38641 aggctgaggc tggctcatcc attaagagga tatctggctt aacagagatg gcacgagcga
    38701 tacagagacg ttgttgctga ccacctgata aggtcaaggc tgacttgtgg agatcgtctt
    38761 taacctgatc ccagagggca gcctgacgaa gggaggtttc tacgatttca tctaggactt
    38821 gcttatcctt aactccagca cgttcatgcg caaaggtaat attacggtaa attgacttag
    38881 caaatggatt ggggcgttga aaaaccattc caatgtgttt acgcatttca taaacgttga
    38941 tttctggacg gttgacatca attccacgat agagaatctg cccagttact ttagcaatat
    39001 caatagtatc attcatgcga ttgagactgc gtaagtaggt agatttcccc gaccccgacg
    39061 gaccaatcaa agctgtaatt ttatttcttt caaattgcat atcaatcccc ttaatggatt
    39121 catttttacc atagtaaaca tggacatcct tagtagaaag ggctactttt tcttcaggaa
    39181 aggtaaggat atgcttctca tcccagttat atgttgacat ggcttctcct ttaggcagcg
    39241 gttaatttct tgtgtagata gcttccgaac ttacgagctc caaagttaaa aatcaggata
    39301 aagatcagga gcacagcggc agaacctgct gatacaatgg ttccatctgg aatagtgcct
    39361 tcactattga ctttccagat atggacagcc aaggtttctg cttgacggaa gatagagatg
    39421 gggctagtca cactgaggat attccagtta gaccagtcaa gagctggcgc cgattgccct
    39481 gctgtataga tcagagctgc agcttcgcca aagatacgac cagatgccaa gacgacaccc
    39541 gttacaatac ctggaagcgc ttctggaata acaacatgaa ccactgtctc ccagcgagaa
    39601 atcccaagag ccagaccagc ctcacgttgg gtatggtgaa cgtgtttcaa actatcctct
    39661 acattacgcg tcatctgagg caagttaaag actgtcaagg ccaaggcacc tgaaatgatt
    39721 gaaaatccat actcaaactg gactacaaag atcaagtaac caaagagacc caccaccact
    39781 gatggtaaag aggacaagat ttcaatacaa gtccgcacaa agttggtaac aggacctttt
    39841 ttagcatatt cagccaagta aatcccagct cccatagaaa gaggtacaga aataatcaag
    39901 gtaatgacca ataggaaaaa ggaattgtaa agctgaatgc caatcccacc acctgcttga
    39961 aaagcagaag accttccagt caagaaagac caagagatat ggggcaagcc ccgaaccaag
    40021 atatagagaa tcaaggaagc caagattgtc acaatgatgc tagcaatcgt atagaggaca
    40081 gctgttgcaa gtttatctaa tttcttagcg cgcataattt ttctttcctc tttctttcgt
    40141 aatcaattta atcacactgt taaaaactaa actcatcaag agcagtacca aggccagtga
    40201 ccagagaaca ttattattta cagttcccat gacagtgttc ccaattccca tagttaatat
    40261 agaagttaaa gttgcagctg gtgtggtcaa ggaagttggg ataacagctg agtttccgac
    40321 aaccatctgg atagctaaag cctcaccaaa ggcacgcgcc atcccaaaga ccactgcagt
    40381 gaaaatacca gaacgggccg ccttcaagat cacacgccag atagtctgcc agcgagtggc
    40441 tcccatagcg aaacttgcct cacgataata acgaggaacc gcacgcaagc tatccgttgt
    40501 cataaaggtt acggtcggca aaatcatgac aaagaggacg gaaatccctg acaaaatccc
    40561 aaaaccagtc ccaccaaaga cactgcgaac aaagggaacg acgacttgca agccaataaa
    40621 tccgtacact actgaaggaa tcccaaccag gagttcaata gctggttgca aaatcttcgc
    40681 cccttttggt gatacttcgg tcataaaaac tgctgcacca atagcaaagg gtgttgcgat
    40741 aagggctgag agaatggtaa cgataaagga acccaaaatc ataggaaggg caccaaattc
    40801 tttactagaa ggattccaag ttcctcccaa aagaaagtca aagatattca caccattgac
    40861 aaagaaggtc gacaagcctt tttgcgctac gaaaaccaaa atcatggcca caaggatgac
    40921 tatcaaagaa agacaggcaa aggtcaaacc ttttcctaat ttctccagac gagaattctt
    40981 tgatggaagc aacattttct tagctaattc ttcttgattc attattgtct cccttccaac
    41041 actgtcacag ttccggcagc atctttttca accttcattt ccttaatcgg aatatacttc
    41101 aatcctttga caatcccttc ttgggtctca tccgagagaa caaaattgag aaattctgca
    41161 gccaactcat tgggctgccc caatgtatac atatgctcat aagaccacaa gggccaatta
    41221 ttgctactta tattttctgg acttaagtca tagccattca acttcatgct tttgaccgaa
    41281 tcatctatat aggtaagaga taaataagag atagctcctg gactttttga tacgattgat
    41341 tttaccgctc catttgaatc ctgctcctga ctttgcatgg cagactgacc ttccataatg
    41401 acagtatcaa aggtagcacg agagccagag ccggctgccc gattgataac agagatgggt
    41461 aagtccttac caccaacctc tttccaattg gttacctcac ctatgaagat ttgacgaagt
    41521 tgctctgtcg ttaggttatc aacatcaacc tccttattga caatcagagc caagccagct
    41581 accgcgacct tgtggtcaac aagagcagaa gcatcaattc cgtctttttc ctcagcaaat
    41641 acatctgagt ttcctatatc aactgcccca gactgaacct gggacaagcc tgtaccagaa
    41701 cctccccctt ggacattgac cgtttttcca acatggatcg tgccaaattc atctgccgct
    41761 acttcaacca agggttgcaa ggcagttgag ccaacagccg ttatggattc tccacgatca
    41821 atccagctag cacagcctac taaacaagcc gtcagccaaa aagcgataag agacagagca
    41881 agcttttttc tttttttcac tgtttttctc ctcgaaaata attatgaata ctgtgaattt
    41941 tttaagtagt tctttatgag ttgacgcatg aattcttacc aaatttctgc gcaattgatt
    42001 atttatataa tataggctat attactcttt cctaacctcc ttttttcata tgtggataaa
    42061 atctcttgtc tatcccttcc cccattgtca cccattatag tcatttcgtg tctctttttc
    42121 ccctttttaa tgcaagggaa attactctcc ttagatgata atccaaaagc tagaaaggta
    42181 tctcaaacct ctctactctc ccagactagt ttacaactaa aaggaaaaga ttcgatttta
    42241 tgagaaatct agtttacaag cggtaagaac gctaataact aaacttcttg tactctttga
    42301 aaatctcttc aaaccagtgt tttgagctat ctatggctag cttcctagtt tgctctttga
    42361 ttttcattga gtagtaaaac tacatgtaat ggcaatcaag atatcaagaa tcatcctact
    42421 aaaaaaatcc atactttcac tataacatag aataagatat ttgactagca ttttcatttg
    42481 aatctgaggc cttttggaaa ataatttttc aaaacatttc cagtaacctt tgcaaagccc
    42541 aagccattgc ctttaaccaa aacttggtac caaccatttg gcagactttc tgccagctga
    42601 acgatttctc cagccgcata cttgacaaac tcttcttggc caatttcaac cgactgttcg
    42661 acctgactcg gtttcaaggc taaaccaaga gcgaaactgg gctcaaagcg tttcttctta
    42721 aaagtaccca gatgcagtcc attgcgagca atcttgagct tccctaaatc tggcaaaagt
    42781 tctggcaaga gataaagctg gtctccaaaa atctgcaaga tacccggtag attgaccttc
    42841 aaatggtttt gggcaaattc ctgccacaag gcaacttgtt cacggctgag gttactctta
    42901 cttgccttaa atttaggagc tggattgtta cccttaaact gtagttgggc aacaaactga
    42961 ccctctccct taaactgatg agggtacatc cgagccgttt ctggcaggtc aataccagct
    43021 accattccat tgatatgctc tactggcaac aagtcaaaat catactcttc cagcaaccaa
    43081 ttgacaatct cttcgttttc ctcgggtgcc caggtacagg tcgaataaac cagacgacca
    43141 ccttcagcta acatggtcac tgcatcctcc agaatttctc tttgcaagct agcacattga
    43201 ctcggataat ctaagctcca atagtccata gcatcaggtt gcttacgaaa cattccttca
    43261 ccagagcaag gggcatcaag aacgattaag tcaaaatagc ctttaaagac cttgaccaag
    43321 cggtcggcag attcattggt caccacgaca tttgtcgctc caaaacgctc catgttttca
    43381 accaaaatct tagcccgttt gcttgaaatt tcattggaaa caagtagccc ctcccctgct
    43441 agataggctg ccagttgagt tgatttgccc cccggtgcag cagccaagtc caagaccttc
    43501 ataccaggac tgggttgggc tacttgagcc accatttgag cagcaggttc ttgcgaataa
    43561 actaaacctg tagcatgctc aggcgatttc cctgaaacct tcccatagtg gccccaaggg
    43621 gtttgagtaa tggcatcaga aaaggaaagt tgctcttctt ttaagggatt gacccgaaag
    43681 gccgaaaccg cttcctcctc aaaagaggca agaaaatctc ttgcctcatc tcctagtatc
    43741 tctttatatt tttcaacaaa tccttctgga aattgcattt aagttctttt cctttcgtaa
    43801 atataggact gaatttcctc ctgcatctca agaggcacca tcatgaccgg ctgtctggtt
    43861 tgaaaatcag gagcttcacc aaaaagggtc acaacccgat agcccagact ttcccctaaa
    43921 atactagctg cggcataatc ccatggttgc agataagtga gataggtcaa caaacgccct
    43981 gacaaaatct tggcaaaact aatggccgca cttccataga cacgaacacc aagaaccgct
    44041 cggctcaaat cagccagccc ccattcattg gtttccagca taccactatt ccctgcaatg
    44101 agaaaatctc caagtggttt agttttaaaa ggagctaggg gcctatcatt tagacaaact
    44161 ggaaattccc caccaccgtg gtaacaatcc cctttgacca catcataaat cagaccaaac
    44221 tgtccctgac cattttcaaa ataagccatc ataacagcaa aatcttcctg ctgggctaca
    44281 aaattattgg taccatcaat gggatcaatg acccaaacct tgccctcttg aaccgaggct
    44341 cgcagacaac cttcttcagc acaaatctta tcctcaggat aacgggacaa aatctcacca
    44401 accaagagtt cctgaacttc tttgtccagt ctggtcacca aatctgttgg agaggacttg
    44461 gtttcaacac gcaagtcttc ctgcatatgg tcaagaatgt actgacctgc tttcttaaca
    44521 agctctttag caaattcaaa tttactttcc aagagaaatc tttccttccc ctttttcttt
    44581 ggcagcctga actgctcggt aaagtgaata gccactaacc gtttcaaatt ctcgtcccaa
    44641 acgtttctct tcgctcttgc ttggcacgac cgctttgaat cccttatagg agtccagtaa
    44701 ctttttagcc tctactttgc cttcataggc agcttcaaca tcattaaaaa aagaaagcac
    44761 tgaagcaagt tcttcagtgc tccacgacaa atctagtggg taactatact gtttgttcat
    44821 taactaatac cagctctcat tcttgcttct tttagttctt gcttacgata actacgaggg
    44881 agaaaagcac gaatctcatc ttcattaaaa ccgatttgca tacgcttggc atcaataata
    44941 attggacgac gcaaaagact aggatactgc tcaatcaaat gaagcaattc cgataccgaa
    45001 atactctcta catcaatatt caatttttga aaaatttttg aacgagttga aatgatgtca
    45061 tcagtaccat tttcggtcaa ggaaaggatg tgttgcaatt cttttcttgt taaaggactg
    45121 gtcataatat tgtgttccac aaagggaacc ttatgttttt ctaaccaggc cttagcctta
    45181 cgacatgatg tacagctcgg tgatagaaat agtgtaatca tgcttttctc ttcttatcta
    45241 tactttgcta cttctattat acaaaaaaat aaggcgcttg actagggatt tttagaaaaa
    45301 aagcctattt tttcaagaaa aataggctgt ttgcgaacga ttgacacaat tggatttggt
    45361 taattcactc ttaacgatgg ttttaaacga tatatatttt tatatatgca aattaaaaac
    45421 atctttcatt tcacttccta cgacttttca gacacagata cccaaagaag ctttcataga
    45481 gggcaaaaaa gaggaggaag gcatgaagaa agaaggtctc tggcaaaatc ataataacag
    45541 gatccttggc tggatcaaaa agccaggtat catctcccac aaagagaatt tgatggaaaa
    45601 gagtaaagaa ttggtcaaaa ccaatcaaaa ctcccccaag tccaatcatc acaggtaaga
    45661 ctactagagt caggagactt tttcgataaa gagacaaaaa gtcctttttc acaatcctat
    45721 tgacaaagac atagaaactt ggcagtgtca ctagagctac tagctgaacc aaatgaaaga
    45781 gattcttgac cactgcgaaa tggtgcagac cagctgctga cgaacgaaaa tcaggcatct
    45841 gtaagacctg actaaaagga ttggtcagat aattcatcaa gatatgaaaa ttgtattgaa
    45901 tggtttctgg ttttagatag actcgattcg ttaagtttag ccactgaatc tccataggat
    45961 agaaaatcca agccagataa atggtcagaa ggattgagag ggagaggaga aagagcatag
    46021 agccccaaaa ggtcaattta gttttcatca aaatcccact ccgcaaggct agaaaccaca
    46081 tgtgtcggtg cgattggcag gccagctact tcttctgcct tggtaaaacc tgtcgtcacc
    46141 aagagtgttg gaatgccatt gtcaatccca gcccggatat cagtcaaata attgtcccca
    46201 accatgatta actcttcacg ttccaaacct aagtgctcaa ccgccttgtc cataatgatg
    46261 gcattgggtt ttccgatata aaccggcttc actcgtgtcg ctacttcaag cagcgtaatc
    46321 agtgagccag cacctggcaa aagaccacgt tccgtcggga tgttgaggtc aggattggtt
    46381 ccgataaaat gggcaccctt ttgaatagca agagttgctg tggcaaattt ttcatagtcg
    46441 acttgccaat ccagaccaac taccacgtag gcagggtttt ccttgtcttc cacataacca
    46501 gccgccttga tggcttcctt gagtcctgct tctccgacga catagacggt cttttcaagc
    46561 cccaaatcat tcatatagtc gatggttgcc aaagtcgctg tgtagacagt cgataggggc
    46621 gtatcgatat taaaattctg agccaacatc tccttaacac tctctggagt gcgagttgta
    46681 ttgttggtta caaagagata gggaatgccc cgcttttgca attcatgaac aaaagtctct
    46741 ccagcaggga ttcggtcttt ccccttataa atggttccgt ctaaatcaat taaatagcct
    46801 ttatatttca tctatttctc cctaagcctt ttttatttct tgccaagtaa tgattgcttg
    46861 ggcattgata accccatcac ttgtaatttc atgcttgctt tccagtccag tccgttcaac
    46921 aaccgatgta atcactccac ctggtcgaac ttccttgaca tacttgaggt tgattttctt
    46981 gggaatatag tgggtcaaaa aatccgctcc catgacctca aaaatccagt ccaagtattt
    47041 actgttattg acatgaccat tcatatccaa gtcgtaaaaa cgaacatggt aatccttgct
    47101 gatcggttct tccaaggact catacttcgg tccacggata agttttttat caaaatcaga
    47161 ctggtaagga gccacaatct caggttcaac agcatggact tttcgactgt cgcggtccat
    47221 gagaacaaag gtcgccatca tatggatgag ctcctgcccc gcttcattat aaatagtaaa
    47281 gcgacggtag caaaaaagtc gattgtagct caaggcttcc gtttcgatgg taatttcttc
    47341 cgcaaaacga ggcaaacgaa ccacctcaat atcatattct gcgataatcc agaccagatt
    47401 atagtcttcc aaaatggcct tatcactaac tcccagttca atcgactgca tccctgaaac
    47461 ttgcagtgac agcaaaatca catctggaag tttgatatga ccgttcatat cagccatatc
    47521 aaaaggaatt ttcattttca tttgataagt taagcccatg atcctactcc aaaataaatc
    47581 gttctgctac agtatctccc aaaaagagac ctctctttgt catgcgaacg tggtcaccct
    47641 caatctgcat gaggccttgt tgaaccaaat ctctgacaat ttctccataa agtccagcaa
    47701 aagactgtcc aaatttttcc tcaaatcgcg ccatggaaac cccggatttc ttgcggagtc
    47761 ccaagaacat ttcttcttcc atttgctcct tttgactcag gtgatcttct gtaatacaag
    47821 cattgccttc ctcaaccgca ctgagataat gacgaatggg accatgattt ttataacgta
    47881 ctccattgac ataaccagat gcccctgcac caataccata gtattcagca ttgtcccagt
    47941 acatgagatt atgacgactt tcaaagccgg gtttggagaa attagaaatc tcataatgct
    48001 caaaacccgc tcgctccagc tctgcaatga tgtactcaaa catctccgct tctagttcct
    48061 ccttaggcag aggcaatttc ccacgtcgca tccggttcat aaagaccgta tggttttcta
    48121 aaatcaaact atacaaactc atgtggggaa tatccagtcc aatggcttta gccacatttt
    48181 cctttacttg ctccatggtc tgaccaggca gagcataaat caaatcaatg gagatgttgt
    48241 caaaaccagc cagtttcaga cgatcgatat tttcataaat atccttctcc aaatgactgc
    48301 gcccaatctt tttcaacatc ttatcatcaa aggtctggac acctagcgaa acacgattga
    48361 cagccgaatt tttcaaaaca gctatcttat ccgcatccaa atcgcctgga ttggcttcaa
    48421 tggtcaactc ttccaagaca gacaagtcca agtttttagt caagccattc agtaacacct
    48481 ccagttgcgg agccgacagg gctgtcggtg ttccaccacc gatataaagg gttgacaact
    48541 tttcaatatc ataagaacga aactcttcca gcagatgctc taaatagctg tcgactggct
    48601 gatttttgat gaagaccttt gaaaaatcac aataataaca aatctgggta caaaatggga
    48661 tgtgcacata ggctgacgtt ggttttttct gcatagtaat tattatacca caaagactag
    48721 attccagata aaaatcacca tccccagata catagtccgt ccggagatgg tgatggttta
    48781 ttcttctgtt atatcaatca caatctcttc tgagtcatca agagcttcgg ctttttcttg
    48841 ccattgttcc ttgagattat ttaattgatt ttttgatgct tctgtcgctt gaaaagcata
    48901 ggatttagct tgagcaagta tactgtccac agtgatttca cctgactcaa cctgttcttt
    48961 tgttttcaga acaaaatctg tagcctgctc cttaacttct gtcagttttt cacagacttg
    49021 ctccttggca tactccggat cttctctcaa atcatctaga aaatcttgag cctgactgca
    49081 aacttgtttg cccttatcac ttgttaaaaa caaggcaaga gctgcacctg aaaccgttcc
    49141 taaaaggatt gaggataatt tacccataag gattctcctt ttttattttt tgaaaaattt
    49201 acttgcaaga cgaagagctg acagacttgc accagtcttg agtgtttttg aaccagctga
    49261 tgaagctttc ttgctcaaga cacgcgcatg gtcattgagg tctgaaacag atagagataa
    49321 atctgcaaca gcactgaaga gtggatcaat tgtagccacc ttgacattga tatcatctgc
    49381 caagacattg accttagcca acaactcatt ggtgtgatgc aaggtcacat ctacatctga
    49441 agtcaaggtt ttaatcgtct tttctgtttc atcgatgaca cgaccaagct tttgtacagt
    49501 aatgatcaga tagaccaaaa agacaatcaa agctagggca acaagaatat atgcaacttc
    49561 taacatttag ttttcctcct ctgtaatata gtaaggggcc ttctttcgat tttgataaat
    49621 aacgatcatt ataccgagac cgataaggac aactgacagc cattgggaca ctcgaaggcc
    49681 gaagaacatg agactatctg ttcgcatacc ttcgatgacc atacgaccga aaccatacca
    49741 aatcaagtaa aaggccgtga tatgacctcg tctgagactc ttccatttcc gtctaaaaat
    49801 cagaatcaag gcaaagccaa gcagattcca tagagactca taaaggaaag tcggttgacg
    49861 gtagctcccc tcaatataca tctggtcacg gataaagcca ggtagataat ccagattatc
    49921 cactgttgca ccataagctt cttggttaaa gaaattaccc caacgcccca aactttgagc
    49981 aatcataacg ctaggcgccg caatatctag aaaatcccaa gtattgatga gtttacggtc
    50041 agcaaagata tagagcacaa gagccccagt tatcaaacca ccgtaaatgg ccaaaccacc
    50101 attccaaatg gcaaaaatct ctcctaaatt ctgactatag taatcaaatc ggaaaataac
    50161 atagtagaga cgagctccta aaatagccaa gggaaaggct actaagataa aatctaaaat
    50221 atcgtctggt atgatcttct ttctaggtgc ttctttcatg gtcaaataaa ccgcaagaat
    50281 caagcctgtc acaatacata aggcatacca acgaatggct aggggtccta gttgaatagc
    50341 aattggatca agcattttgc acctcatttc gagctatgag acttgtcagt cgttcgtcga
    50401 acaaacgggt agcatcaaag cccatttcct tggcacgata attcatggca gctgcctcaa
    50461 tcacaacaga gatattacga cctgttttaa ctggaatacg aatacgagga atggctacgc
    50521 cagaaacttc aagttcctct gcattgtttc caagacgatc aaaggtctta tgcgtatcgt
    50581 aattttccaa atagacagca agctgaacct gtgaagaatc cttgacagca ctcgcaccgt
    50641 agagactcat aacatcgata ataccaaccc cacgaatttc aatcaagtgt ttcaaaattt
    50701 cagctggttc accccagaga gtaatctcat ccttggcaaa gatatcgaca cggtcatcgg
    50761 ctaccaaacg gtgaccacgt ttgacaagct caagacctgt ctcgctctta ccaattccac
    50821 tatctccctg aatcaagacg cccatcccat aaatatccat caagacaccg tgcacactgg
    50881 tacgttctgc caaacgagaa tccagatagc tagataactc tccagataaa cgactggtag
    50941 ctgcacggct ggttaaaata gcaatcttac attctctagc agcctttaac atctcctctg
    51001 gaaccaccaa accacgggca acaatgactg ctggtgtctc aggtagaaac atttttttca
    51061 aaacttcata acggctgttg gaaggcatgc tgatcagata agaccactcc ttcatcccca
    51121 aaagttgaat ccgctctggt gtatagtagt caaaatagcc tgtcatttca agaccaggtc
    51181 gcgtaatatc cgctgtattg atttcctttt caagcaactc tggttcacca tagacaatat
    51241 ctagtctaag cttttcaatc acttctttta ctaaaaccga catcatttcc tccttcaaat
    51301 gagttcttct ctctattata tcaaattgta ggaggaagtt tcagattttt gcaggctttg
    51361 gagtatttat ttaaaagaaa aaggactaga tttctctagc ctttcatttc aattagaatt
    51421 ttttacgttt acgagctact tctgatttac gtttacgttt tacagaaggt ttttcataga
    51481 attcacgttt gcgtgtttct tgaagagtac cagctttagt aaccgcacgt ttgaaacggc
    51541 gaagtgcgtc gtcaagagat tcattcttac gtactactgt tttagacatt tttttcactc
    51601 ccttcaagtt caatatctat ttcattctac acgtaaaagg aataattgtc aagcaaaaat
    51661 gcggtttaat tttgattttt tcttccattt atacaagagt tgaaagcgtt caatagaaca
    51721 ttgctttttt atttttcgag taagctaagc gcttcagcat ctgcgatgat ggttacatca
    51781 gggtgatttt ggaggctact tgcaggtagg ttctcagtca ctgggccaga tactgttccg
    51841 gcaatggctt ctgctttcga ctcaccgtaa gcaaaaagaa taatagactt ggcatccaaa
    51901 atgtttttaa tccccattga aatagcttgg gttgggacgt cttcaatctt agcaaagaag
    51961 cgtgcattgg cttcgatagt agactggtca agttctacta gatgcgtttg actgtcaaat
    52021 ggagtaccag gctcattaaa gccgatatgc ccattgcgac cgattcccaa gatttggagg
    52081 tcaactggat ggtcagccaa aatttggttg tagcgttcaa cttcagcttc agcattgtcc
    52141 ttaacaccac gaggcaagaa actttcttta aatggttttt ggttgaacaa gttttcttgc
    52201 atgaagtaac gataagactg tggattgtcc ccatcaaggc ccacatactc atcaaggttg
    52261 acactggtta gatttgaaaa atcaaggtca ctctcaacaa tttccttgta aaattcaagt
    52321 gggctacttc ctgtcgcaag tcctagagtt tgagctccat tagccaattt ttccttcaaa
    52381 atctcaaaag caacttttcc accttgaact tggttttcaa ctttaataac tttcatcttt
    52441 tcatcctcca tttctgtcta tatttattat atggtataga ccaatttttg tcaagtgaaa
    52501 acgatttaat ttctaaaaaa agagcgtcca aacttgaaac gtgttataat ggataggatt
    52561 agaacttaga aagaatgaac agatatatga atacagctga ttttgatttc cacttgccag
    52621 aggaattgat tgcccaaacg ccccttgaaa aacgtgatgc ctccaaactc ctcatcgtca
    52681 accgtgagac aggagaaatg caagataaac acttccactc tattattgat atgctggaac
    52741 ctggtgatgc ccttgtcatg aacgacaccc gagttctccc tgcccgcctc tatggtcaaa
    52801 aagtggaaac aggaggtcat gtggaacttc tcctccttaa gaacactagt ggagacgagt
    52861 gggaagttct ggctaaacct gccaaacgcc tcaaggtcgg tactcgtatc agctttggtg
    52921 atggccgcct cagcgctgtc gttacagaag aattgaccca cgggggacgc attgtccgct
    52981 ttgaatacca aggaattttc ctagaagtct tggaaagtct gggagaaatg cctctgccac
    53041 cttatatcca cgaaaaatta gatgaccgtg aacgttatca aaccgtctac gccaaggaaa
    53101 gcggctctgc tgcagcaccg actgctggtc ttcacttcac caaagaactg ctggcagaaa
    53161 tccaagctaa gggtgttcat ctagtctatc tgactctcca tgtcggactc ggaaccttta
    53221 gacctgtttc tgtggataat ctggacgaac acgaaatgca ttcagagttc tatcaacttt
    53281 ctgaggaagc tgctgccacc cttcgctctg tcaaagaaaa tggtggtcgc gtcatcgctg
    53341 tcggaaccac ttctatccgc accttggaaa ctattggttc caagtttgat gggcaaatcc
    53401 aagcagattc tggttggacc aatatcttta tcaaacctgg gtatgagtgg aaggtcgtgg
    53461 atgccttctc aaccaacttc catctgccaa aatcaactct ggtcatgttg gtttctgcct
    53521 ttgcaggccg tgaattagtc ttagatgcct accaccatgc catccaagaa cactaccgct
    53581 tcttcagttt tggtgacgcc atgtttattt attgagaaag aatttctcta aatcttctaa
    53641 taccaataaa tcgctaagat attatttcaa agaacatcta caattgaaac tctagctagc
    53701 tgtagaagac gcctagtaca ttgaaattaa aatgcttccc ccctagcttc gaaaatattg
    53761 ccatagattg cgttgactct ccaaattgat tcatctatat tttatttcag cttcctatat
    53821 tttcttcgct gtttgtaaat caaaatgcaa gacacatgag tagcaccata tttgttactc
    53881 ttatctgtcc tctcaagaga ctattatgag ttatttcaga atcattcact actttgaccc
    53941 tgactctcct tagtctcaaa atcaaagact tatactcttc aaaaatctct tcaaaccgcg
    54001 tcaacgtcac cttggattat atatgtgact gacttcgtca gttctatcta caacctcaaa
    54061 gcagtacttt gagcaacctg cgactagttt tctagtttgc tctttgattt tcattgagta
    54121 ttaaacaaaa agtgaacaaa tctgaattct aatgtacaga agactaggct tgttcacttt
    54181 tttatagtcg ctataagatg accttatcta tagcttttta tatataatta tatattcaga
    54241 catactatta tcaattttgt cgcagggagg aatctgttaa cgcacccatt caccattatc
    54301 attgactcta tagccatcta tacttgtatt gaccgctaac tcacccgatg tatttacata
    54361 ataccattta ccaccaactt ggaaccattg attgactttc atagaaccgt tgctgttgag
    54421 gtagtaccat gaaccattaa cttgtaccca acctgttgcc atggaaccat cagtattata
    54481 aaaataccac ataccatttt cttgtttcca gcctgttgtt ggagcaactg ctttagctgg
    54541 ttctactgct acatctgttc cttggttaga tgtaacagat acaggatacg aaggaataga
    54601 tgattgctca ggaacaacaa ctttttcagg ttctctcgtc cctctcctta tacgtctttt
    54661 taccatctct ttagtaattt gacgagaagt agtttcttca attgttccat cacgttcatc
    54721 tacagtatag attgtagtaa gagtaattta ccaatttctc ctacttcttc tacttcttga
    54781 cttttatcaa gagttgggcc atcgagatat tctgtttcga ttggaatttc ttggacaaga
    54841 acttggggct tggttccttt tttaacaact cttgtttgag agtcttcttt ttgacttaaa
    54901 gtactctcag ttacttgtcc actctttcca tctacatcat aagttatcgt tgtaactgtt
    54961 ttcccattct ttcctagagt aatctcttgc tcctgtcctg cagaaaggtc attgtctgct
    55021 tcatatttag tagcaaatgg aacaagaact tcttcaacct tgcttttagc tggaactttg
    55081 ataactgtat ccgtggcttc ttttctatca acagtaacct gttcggtaac atgaccagtc
    55141 tctggattaa catcgtaggt ccttgtcgta gttacatagc catcctctcc atcaattgta
    55201 acaggatttt cactacggtc ttttgtttca tctttttcat aacgaattcg cgtacttgaa
    55261 attttcttgg ttactacctt aggtttagtc gctactttta caataatatc cccattgtca
    55321 gcgtcatcat actctattcc ctcttcttta tctctagtat catctctgac atattgaatc
    55381 ccatcagcag catgaacaaa acttgtattc agattcctcc taaaaataaa gttagcccgg
    55441 ttaccgcaga accaaaaatc tttccgagtt tacgtaatgc atagcgctta ttagtattag
    55501 attttgccat tacatcctac ttctagtata gcatcttttc tatcaaacat taaacaatat
    55561 actttatata taaaatagac ttagaatgat atattgatta ttgaactaac actttaacta
    55621 tatcgtaatc aatctcatat ataaaggatt gcagacatct tatctaaata catgctaata
    55681 tatttagata caaacattcc aacttgataa ttttcactca tctttcatca ttccttatac
    55741 aactatgcag tataaataga atagttttct catcagaatg agactatttt aatattagat
    55801 attttgatag aaaaaacata aataaaattg gttgaattta attccctaac tcgatagagg
    55861 attctatttt aaatttaaca acagctagga ttacactata aaaagtacat taccacctgt
    55921 tcggctggag aatctagtcg attagctccc tcttagttac aagcttcaag cgatttttta
    55981 actaatacta aaccagatta aagaaggaac tagagcatct gtcttgtact aatcaatatg
    56041 ctattttaaa attgcaaata aacttggaat gctaattatt atatttacaa taaatagttg
    56101 acttcgatag aaacagaaaa tagaattcaa cattcttccc tacttatacc ataataaata
    56161 agatccgcaa gatagccttt tctctctaca ccattaacaa tggtttgtag ataggacatt
    56221 ccagcctttt ccatgacacg acctgaagct gggttgagac tggcataacg tgctctgacc
    56281 ttttgaaaac ctgcttgagt aaaacaaaag tccaagacag ctttcaaggc ctctgtcatc
    56341 ataccatgtc cccagtaagc cttgcctagc acatagccga tttcacagct taaatcagcc
    56401 tcgtctatct taacgatgct gatatctcct atcacttgct ctgggttttc ttttagacaa
    56461 atggcccatt tgtaatagtt gagattagta taggaagcaa cccaattgcg aatcgagttt
    56521 cgagtgattt cgacatcagg atggggatcc caggtaacat aggtcagatt ctcagcggat
    56581 gaagcccaat tttgaaacat ggcttctgca tcactctcca caaatcttct taaaatcaaa
    56641 cgttctgtct gtaatatttg cgtaccgata gatttcatga tgctacctca cttccttatt
    56701 tctatgctcg tagtaaaagg ctcaactcag taacagctag aaaacgagtt tgtcttctaa
    56761 tttcttgacg cagtcgctgc ctggtttgaa atgcgctcta gcaagctttt tcaaacctag
    56821 tcatcgttgc aggggtaaga cgatgaaatc gaactcttcg agttaccgaa tctgcctcat
    56881 tttcttattt ctaaactcga ggttcaagat tccccggacc ttcttcgctt tctcatttct
    56941 aggctcaggg taaaaacctc caatggaggt ttttactccc aaaagtcatc aaatacagtg
    57001 atgggtaagt ggcgtttgtg ttggcctttg tgccaccagt tttcaatggt cgcttgagct
    57061 tctgggctga ttgttttgcc ttctaggtaa tcgtcaatct ctgcataggt gactccaagt
    57121 gcgacttcgt cagctaggcc tggtttgtct tcttctaggt ctgccgttgg gattttttca
    57181 taaagggctg gctctgcgcc aagtttctgc aagagctgtt ttccttggcg tttattgagg
    57241 cggtaaagag ggagaatatc cgcaccgccg tcaccaaact tggtaaagaa acctgtgata
    57301 ttttccgcgg cgtggtctgt tccaatgacc gctccgctat gggaaccagc aagggcatac
    57361 tgagcaatca tacggcaacg tgccttgata ttccccttgt tgaagtctga aacaggacta
    57421 cctgtcgctt caactgcagc tgtcatggca tcagctgatt ccttgatatt cacaaccaag
    57481 ctgacatctg gctggatgaa ggctagggct ttttgagcat ctgcttcatc agcttgcact
    57541 ccgtatggca ggcggacagc gataaatttg tagctgtcgt ctcccgtttc agctcgcagt
    57601 tcttccatag ctaattgcgc caaacgccct gtcaaggttg agtcttgtcc cccagaaatc
    57661 cctagtacaa aggtttttag gaagggatgt tttttcagat atctttttaa gaaatcaata
    57721 gaacgacgga tttcttcctg ggcatcaatc actggtttga cacccagctc ttggataatc
    57781 gtttcttgca aactcattct tcttctcctt caccaagggc ttccttgcgc atcttatcaa
    57841 tcaagtccat cttatcttgc catacatcac gcgccaaatc cactggatag tgctgcggat
    57901 tgagcacacg cttatactca tcccacaact tgtcaaattc tttacgggca taatcctgaa
    57961 tgtcagtcaa actaggcaag ttgtaaacta atattccttc tttgaagata tccaccaaga
    58021 gaggaacggc atcaaaatta cgaaccgtct tcttgatgta tgtataggtc ggatggaaca
    58081 tcttgatttc tgtcatgtag ctaatatcca caccatcata agtgatgtag tcaccttctg
    58141 acttaccttt ttcacgactg gtaatgcgcc acacctgctt cttacctggc gtagagactt
    58201 tttcagcatt attagacagc ttaatcgtat tgcgcatctg accagtttca tcttcgattg
    58261 caacaatctt ataaactgca ccaagagctg gctggtcata agctgtaatc agcttggtac
    58321 ccacgcccca gacatcaatc ttggcctttt gcatcttgag gtttaggatg gtattttcat
    58381 ctagatcatt agaagcataa atcttagcct ctgtaaatcc agcctcgtcc agttgctgac
    58441 ggactttctt agaaatgtag gcaatatccc cagagtcaat ccgcacaccc ataaagttaa
    58501 tctgatcacc cagctcacgc gccacctgaa tggcagctgg tacaccgatg cgaagggtgt
    58561 cataggtatc cacaagaaag acacaatttt tgtgggtcgc agcgtaagcc ttgaaagctt
    58621 catagtcatt gccataaacc tgtaccaagg catgggcatg ggttcccaaa acaggaatgt
    58681 caaagagctt acccgcacgc acgttgctgg ttccattggc gccaccaatc acagctgcgc
    58741 gtgttcccca gatggccgca tccatttctt gagcccgacg tgtcccaaac tccatcaagg
    58801 ggtcatcttc gataaccgaa cgaatacgag ctgccttcgt cgccaccaag gtctggtagt
    58861 tgacgatgtt caaaagagcc gtttcgacca actgacattg ggctagaggt ccttccacct
    58921 gcacaatcgg ttcattagca aaaaccaaat ccccttcttg ggcagaacga acggtcaact
    58981 ccaacttgaa attgcgaagg taatccaaga acgccccatg ataaccaagc gactccaaat
    59041 aggctatatc actatctgaa aaacgcaagt cttcaagata gttcacaatt ctttccaaac
    59101 ctgcaaaaac cgcatagccg ttcttaaaag gctgttggcg gaaatacacc tcaaagaccg
    59161 ccttcttatt gtgaatccct tggtcaaagt aaacctgcat catgttgatc tggtacaagt
    59221 ccgtgtgcaa tgtcaaacta tcatctggat acatactttt cctacttcct tagctagaaa
    59281 cccatgaaaa ttttcaagaa ctttcatgta ttccaataaa ttagtactat tatatcacat
    59341 tttagctgga ttgagaaaag agtaacaagc tattctccac tctccaattc atccatatct
    59401 tgttcaaatt ttttctgagc ccattcgcca tagctcttaa gaccaagatt gccaataaag
    59461 acccacggaa ggtaaatgac ataagtaatg acccaagcag acaggtattt aaaattcaaa
    59521 ggattgtgct gataaatttc tatgttgaat tgataattct gcaacatcaa aagagccgta
    59581 atagccaagg ttaggaaaaa acaacccaaa atcgtaaaat gaaaacgact atagtaggtc
    59641 actcccagat aacgggcgcg attgaaaaag taaaatgtcc ctatgatgat aacgattagc
    59701 agcatattag aattaaaaag gcttggtgct aatactgaaa tgatataaga taggagcgac
    59761 aaagcaatgc agatatagaa actttcagat cccgctttat tgaacagttg ttcttctctt
    59821 tcgtctagta attgataata ataaaatcta tttttcatct tcttcctccc aaaatagttg
    59881 gtctagggtt ttccctaaac atctgcaaat agactggcag agcgagagac tgggattgta
    59941 tttccccgcc tctatcaaac caatagtctg gcgcgtcacc ccgacagcat ctgctagttg
    60001 accttgagtt aaatcaagct ctacccgagc taattttaat tttaaatttt taaccacctt
    60061 cgtcctcctt ataattttaa tattcatcta ctcttaaaaa attccaaact aacacaagct
    60121 gtcagctatt tattataacc ccattaattt gcactccagt attatcttca gccgaaaatc
    60181 agtattttag gttgtttgaa ataaacttcc tagtttactc ttttattttt atttagtatt
    60241 agctttagta ggagctttta aacgagtttt tattgcttat atttcttgtt tagtttagtt
    60301 ggtttcatat cactattata taatgctttt gaaaatgagc ctagtataag tcaaaaacgt
    60361 gttgaatagt gaaagcagga gcataccaag atgactgatt tttttactgt attttaggta
    60421 tgcaaaataa tactaaatga aactaaaatg aatacttctt gcttttcttg agagtgaaaa
    60481 agtacaataa aatgattgta gtgattagca caagatactg actaatagac atcgtatttg
    60541 aagtcacaaa tacaggtaaa gaataaaaag gaagaagttc aattgctttg ataaacaaat
    60601 cattactagt attcatcata atcgtattta atatattagg gataaagagt agtaaagcta
    60661 ctaaaatacc aaataccaag ccacttttca atttgtataa atagaaaatg taagataata
    60721 gaaaataaaa caggactaac aaaattgtat tgactacaat agctactata aaatctaatc
    60781 ctaaatcatc tggaataccc aatttactta ctatgactag taacacaatg ccattcaaag
    60841 cataaataat ggaaactgag atggcatata gaaaattaga caagacgtaa atcatccgat
    60901 tcttctgttg attataaaac aaacttaccg tattgtggga aaaatctcta ctaatgactc
    60961 gattagcatg tataacagcc attaacatac cgagcatggc ataaaagttt gaaatatgct
    61021 taataccaag cgatgtccct tgagtcttta gaataaagaa tgtaagcaat atcggcggta
    61081 taaacgagat aagcaaactg agatatatta cgcctgatga atataaattt cttatatttt
    61141 ccttaagaaa attcaattta tttaatttca tgattataac cttcctttat tttgaacgat
    61201 ttaggtaaat atctttaagc gtctcttttt tagtttcaaa atcaactact ttaatagagt
    61261 tttcgttaaa aaatttaaaa agctcactac tttgaatatt cccagacata gtaattctca
    61321 atccctcttc ctgaacaata tctccaaatt cttgtttggt aatgaaaatg tctctatctg
    61381 tagctgatga aaaagctatc tcaaacaaga aattatgact atcttttcct actttttgaa
    61441 atgtcaaaag cccgctctcc aagaaaagaa ccctctcaca aatttcttca atatcttcta
    61501 atttatgact cgatattaaa attcccacat tttcatgtaa agctaaattt tttagaaccg
    61561 ataaaactat ttgtgatgat tcaatatcta aaccattagt cggttcatct aaaatcaata
    61621 tatcaggttc cgtaacgaga gttagaagca aagctaattt ttgttttgta cccaaagaat
    61681 aggtctttac ttttttatta atagactgag tcaaatctaa ctcttggatc aaacttctaa
    61741 atctttcttg attgtagtca acaccatata aatttgacaa atattttaaa ttctctaaac
    61801 ctgttttaga taaaaataat tttggttctt cgattaaata cccaatatta tcactgctta
    61861 taatattacc tgaagtcggt tgattattct gagcaagaat tttcatcaac gtactcttac
    61921 caactccatt tctccctact agaccaacaa tttcaccctt gttaagtgca aaatttatgt
    61981 ctttgagaat gattgaatga ccataatact tacttacatt tataacttac attttttatt
    62041 cctccattaa tattcatggt ttgctctttg attcttattg agtttaaaaa gttgcgcctc
    62101 tttttaacaa cattatatca tatatctaac ttaatgcaat atataaatgt cattttgtaa
    62161 aattttatta acaaaaaact ctctacaaca aaataataga gagttttctg cttattaatt
    62221 tttttcaaaa tatctaagac atcacttctt tgtttaattt gataggcttt gatacctaag
    62281 ctccgacttt atcacttaaa aaataaaaaa ggacagctaa tctcttgcgc atcaagggat
    62341 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    62401 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaa
//
LOCUS       DAVHBD010000006        55884 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000006 DAVHBD010000000
VERSION     DAVHBD010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55884
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.006"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(38..1006)
                     /locus_tag="VVK04_000388"
     CDS             complement(38..1006)
                     /locus_tag="VVK04_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU3989092.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            1142..1999
                     /locus_tag="VVK04_000389"
     CDS             1142..1999
                     /locus_tag="VVK04_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU3989093.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     ARISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            1986..2765
                     /locus_tag="VVK04_000390"
     CDS             1986..2765
                     /locus_tag="VVK04_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU3989094.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            2789..4141
                     /locus_tag="VVK04_000391"
     CDS             2789..4141
                     /locus_tag="VVK04_000391"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU3989095.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            4215..4589
                     /locus_tag="VVK04_000392"
     CDS             4215..4589
                     /locus_tag="VVK04_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU3989096.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            4591..5439
                     /locus_tag="VVK04_000393"
     CDS             4591..5439
                     /locus_tag="VVK04_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU3989097.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            5604..6371
                     /locus_tag="VVK04_000394"
     CDS             5604..6371
                     /locus_tag="VVK04_000394"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU3989098.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDLDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            6383..7567
                     /locus_tag="VVK04_000395"
     CDS             6383..7567
                     /locus_tag="VVK04_000395"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU3989099.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNLQAITKKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            7564..9435
                     /locus_tag="VVK04_000396"
     CDS             7564..9435
                     /locus_tag="VVK04_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU3989100.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(9578..10762)
                     /gene="mntE"
                     /locus_tag="VVK04_000397"
     CDS             complement(9578..10762)
                     /gene="mntE"
                     /locus_tag="VVK04_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU3989101.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            11066..13762
                     /locus_tag="VVK04_000398"
     CDS             11066..13762
                     /locus_tag="VVK04_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU3989102.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            13775..14566
                     /gene="yghU"
                     /locus_tag="VVK04_000399"
     CDS             13775..14566
                     /gene="yghU"
                     /locus_tag="VVK04_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU3989103.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            14682..15092
                     /locus_tag="VVK04_000400"
     CDS             14682..15092
                     /locus_tag="VVK04_000400"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU3989104.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            15104..16699
                     /locus_tag="VVK04_000401"
     CDS             15104..16699
                     /locus_tag="VVK04_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989105.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            16765..16929
                     /locus_tag="VVK04_000402"
     CDS             16765..16929
                     /locus_tag="VVK04_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU3989106.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            17008..17736
                     /gene="yaaA"
                     /locus_tag="VVK04_000403"
     CDS             17008..17736
                     /gene="yaaA"
                     /locus_tag="VVK04_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU3989107.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(17787..19271)
                     /locus_tag="VVK04_000404"
     CDS             complement(17787..19271)
                     /locus_tag="VVK04_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU3989108.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILELLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            19487..25045
                     /locus_tag="VVK04_000405"
     CDS             19487..25045
                     /locus_tag="VVK04_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682791.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU3989109.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLLGTALVLGVAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASTNEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRTAGSGFRAAGPENKPILNPNNTIAFSDISQGSHSFRGIGHSRGGREIHYDVT
                     TVRRGNNINFTINYFAPGNLREFVNNNFILDKGTGYGEPTPATVITPNLRNQVKNISK
                     GGNFVSHSGYSLEAAVETNKSQTITFSLPITNPNGDLSLRLRPVEFNVDQGGSGTGTS
                     NDPYSNSNYYFETDPLYLDANPNQANPLTTSFNTKVDFQTLYIPTTKLAEGVTELVSE
                     GVEGEKSQAYRLHKFGDQYVLGLPVGNATTVTAAKPRVMKYGIGKIAATQNKTGDTNH
                     IKFYLDKDGDGVFNNQDEVILNTDIKDGERGPTGATGAQGPAGPKGADGQRGPAGPQG
                     PKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTN
                     GQSPTITATRSVQNGKNGVLVTITPVEGRPQTTFVEDGQKGADGKTPTVTITEGQNGT
                     HTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDV
                     YVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDG
                     KDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGADGAKGE
                     KGDRGERGLTGAQGAKGADGAAGRDGRDGRDGKDVLNGKVNPEANQGKDGDKYVNTET
                     GDVFVKNNGNWDKEGNIKGSKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGKDP
                     VTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGKYTPGTDELLGS
                     EMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGKS
                     PTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQDGQTPTITTQRG
                     QDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAATPT
                     RNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTIT
                     VQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGKT
                     PKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNPD
                     GTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVTI
                     TDEQNGTHKISVLNGDGTTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSETTV
                     RDGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTG
                     ADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPTV
                     TVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTV
                     TKTVIKDGKDGRDGRDGRDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKP
                     VPAVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQSDYISVLLGSGILL
                     SLYVGRRKED"
     gene            complement(25283..25831)
                     /locus_tag="VVK04_000406"
     CDS             complement(25283..25831)
                     /locus_tag="VVK04_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU3989110.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            26152..26640
                     /locus_tag="VVK04_000407"
     CDS             26152..26640
                     /locus_tag="VVK04_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU3989111.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            26637..27824
                     /locus_tag="VVK04_000408"
     CDS             26637..27824
                     /locus_tag="VVK04_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU3989112.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYSFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            27817..28182
                     /locus_tag="VVK04_000409"
     CDS             27817..28182
                     /locus_tag="VVK04_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU3989113.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLVPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGIEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            28198..29544
                     /gene="asnS"
                     /locus_tag="VVK04_000410"
     CDS             28198..29544
                     /gene="asnS"
                     /locus_tag="VVK04_000410"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU3989114.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGIKHIREAIPFPRMLHRIKP"
     gene            29697..29987
                     /locus_tag="VVK04_000411"
     CDS             29697..29987
                     /locus_tag="VVK04_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU3989115.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            29999..30469
                     /gene="ssbA"
                     /locus_tag="VVK04_000412"
     CDS             29999..30469
                     /gene="ssbA"
                     /locus_tag="VVK04_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU3989116.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            30501..30740
                     /locus_tag="VVK04_000413"
     CDS             30501..30740
                     /locus_tag="VVK04_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU3989117.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            31035..32435
                     /locus_tag="VVK04_000414"
     CDS             31035..32435
                     /locus_tag="VVK04_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU3989118.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            32437..32796
                     /locus_tag="VVK04_000415"
     CDS             32437..32796
                     /locus_tag="VVK04_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU3989119.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHYLKKKK"
     gene            32850..33599
                     /locus_tag="VVK04_000416"
     CDS             32850..33599
                     /locus_tag="VVK04_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU3989120.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPHSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            33589..33888
                     /locus_tag="VVK04_000417"
     CDS             33589..33888
                     /locus_tag="VVK04_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU3989121.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            33959..34894
                     /locus_tag="VVK04_000418"
     CDS             33959..34894
                     /locus_tag="VVK04_000418"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU3989122.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMYKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            34980..35492
                     /locus_tag="VVK04_000419"
     CDS             34980..35492
                     /locus_tag="VVK04_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU3989123.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            35517..36125
                     /locus_tag="VVK04_000420"
     CDS             35517..36125
                     /locus_tag="VVK04_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU3989124.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            36226..36420
                     /locus_tag="VVK04_000421"
     CDS             36226..36420
                     /locus_tag="VVK04_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU3989125.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(36466..37911)
                     /locus_tag="VVK04_000422"
     CDS             complement(36466..37911)
                     /locus_tag="VVK04_000422"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU3989126.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLTGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            38017..39639
                     /locus_tag="VVK04_000423"
     CDS             38017..39639
                     /locus_tag="VVK04_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU3989127.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVVLVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            39842..41800
                     /locus_tag="VVK04_000424"
     CDS             39842..41800
                     /locus_tag="VVK04_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3989128.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVNIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKVQEELAKHVK"
     gene            41972..42907
                     /locus_tag="VVK04_000425"
     CDS             41972..42907
                     /locus_tag="VVK04_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989129.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            42932..43654
                     /locus_tag="VVK04_000426"
     CDS             42932..43654
                     /locus_tag="VVK04_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3989130.1"
                     /translation="MNFNHVYFGYDENRPILKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLEQFYKPLAGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDEFTANLDADSEYAIISILYSALKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            43812..44906
                     /locus_tag="VVK04_000427"
     CDS             43812..44906
                     /locus_tag="VVK04_000427"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU3989131.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            44914..46080
                     /locus_tag="VVK04_000428"
     CDS             44914..46080
                     /locus_tag="VVK04_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU3989132.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSPYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            46173..49271
                     /locus_tag="VVK04_000429"
     CDS             46173..49271
                     /locus_tag="VVK04_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU3989133.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMVLPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPSKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            49319..49936
                     /locus_tag="VVK04_000430"
     CDS             49319..49936
                     /locus_tag="VVK04_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU3989134.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTAPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            49947..51281
                     /locus_tag="VVK04_000431"
     CDS             49947..51281
                     /locus_tag="VVK04_000431"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU3989135.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            51291..51755
                     /locus_tag="VVK04_000432"
     CDS             51291..51755
                     /locus_tag="VVK04_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989136.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            51752..52246
                     /locus_tag="VVK04_000433"
     CDS             51752..52246
                     /locus_tag="VVK04_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989137.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            52327..53982
                     /gene="mltG"
                     /locus_tag="VVK04_000434"
     CDS             52327..53982
                     /gene="mltG"
                     /locus_tag="VVK04_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU3989138.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            54053..54535
                     /gene="greA"
                     /locus_tag="VVK04_000435"
     CDS             54053..54535
                     /gene="greA"
                     /locus_tag="VVK04_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU3989139.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFVGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            55043..55441
                     /locus_tag="VVK04_000436"
     CDS             55043..55441
                     /locus_tag="VVK04_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989140.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT        17064 a        10362 c        12589 g        15869 t
ORIGIN      
        1 ataaaaccac gaatcctatg tgactcgtgg ttctttttta taaactggta gagtgttttg
       61 gttgtacttt ttgttcaggg tcaatgtagt tgatagcgtt gttgacagca gttggagctt
      121 ctccgaggcc tgtcgcaatc agatcaattt ttccgtcata gtagcagcag tcaccgatag
      181 catagatacc tgcttggctg gattcttgtt tgctgttgac gataatcttg tgacggttga
      241 ggtcgagccc ccagttttta aggttaccga cagaagattt gaaaccatag ttgacaaaga
      301 ggtggtctag gtcaatggtt tcagtttcat cagatttgac ttttgtgatt tcaagtttat
      361 caagtgtttt tccatttcca aggagttggc caggggcgaa tggtgtcttg atggttacag
      421 atgattcttg caaggcttga acactgtgtt ccaaggcacg gaaattatct ctgcggtgaa
      481 caagggtagt tggtgcgatt ttttcaaaag ccaaagccca atccacagcc gagtctcccc
      541 caccaagaat cgtcactttc ttaccagcgt attgctgaat gttagaaacg tggtagtgga
      601 tattttcata gccctcaacc ccttcaagtt ccagcggacg tggtttgaag gcaccgccac
      661 ccatagcgat gataactgtt ttagtcaggt gacttccttt agaagttgtg atggcaaatt
      721 cttcttcttg tttgtcaatc tcaagaaccg tttcattgag atgaataggg gtatcaaatc
      781 catttagctg ttcaatcaag cggttagtca actcttctcc agtcaggttt gggaagcctg
      841 gtacgtctag gatttccttt tcagggtaga gaatagcagg ttgtccacct agctggggaa
      901 gagagtcgat gatttgaacc ttggcttggc gtaggtgggc ataaaaggct gcaaaaagcc
      961 cgacaggacc gccacccaca atggtaatat catagagttg agacatagtt tctcctttgt
     1021 tttttctagt cagtttattt tatcatattt ttgttcaatg taaaatggac taggataggg
     1081 aaaaaaatgc cagaaaatgg tataatagga cgaaagtgtt ttgataggga ggatatcagg
     1141 gatgaatttt caacaattat ccaatctgca atattggacc agtttgtttg caagtccatg
     1201 gacgatagct atcaatctga ttgatatttt gattgttgct tatattttat accattttac
     1261 aaaagctatt gcaggaacca agattatgat tttggtacgt ggagttttgg tgtttatttt
     1321 agctcaaatc cttgcaaata tgattggttt gactacgatt tcttggttaa tcaatcaaat
     1381 tattacttat ggggttattg cggcggttgt tatcttttct ccagagattc ggactggttt
     1441 ggaacgtttg ggaagagcga cagatttctt ttccaatgcc cctattagtg ctgaggaaca
     1501 gatgattcgt gcctttgtta agtctgttga atacatgagt cctcgtaaaa tcggggcctt
     1561 ggttgctatt cagcgtgtac gtaccttgca ggagtatatt tcgacaggaa ttcccttgga
     1621 tgctaggatt tctgcagaac ttctcattaa catttttatt cccaacactc ccctacatga
     1681 tggtgcggtg attatcaaag aagaacgtat cgctgtgacg tctgcctatc tgcccttgac
     1741 aaaaaacaca gggatttcca aggaatttgg gaccagacac cgggcggcta tcggtttatc
     1801 agaagtctca gatgccttga cttttgtcgt atcagaggaa acgggaggaa tttcgataac
     1861 ctataatgga aggtttaagc acaacctaac acttgatgaa tttgaaacag aattacgtga
     1921 aatcttactt ccaaaagagg aagtgggtct tagttttaaa gaacgattgc taggaggatg
     1981 gaaacatgaa aaaaaatagt ttatatatca tatcctcact cttttttgct tgtgtcttat
     2041 ttgtctatgc tacggcgacg aattttcaaa acagtaccag tgctaggcag gtaaaaacgg
     2101 aaacctatac taatacagta acaaatgtcc ctattgacat acgctataat agtgataagt
     2161 attttattag cggttttgct tcagaagtat cagtggtctt gactggtgca aatcgcctat
     2221 cgctagctag tgaaatgcaa gaaagtacac gtaaattcaa ggttactgct gacctaacag
     2281 atgccggtgt tggaacgatt gaagttcctt tgagcattga agatttaccc aatgggctga
     2341 ccgctgtggc gactccgcaa aaaattacag tcaagattgg taagaaggct cagaaggata
     2401 aggtaaagat tgtaccagag attgacccta gtcaaattga tagtcgggtg caaattgaaa
     2461 atgtcatggt gtcagataaa gaagtgtcga ttacgagtga ccaagagaca ttggatagaa
     2521 ttgataagat tatcgctgtc ttgccaacta gcgaacgtat aacaggtaat tacagtggtt
     2581 cagtaccttt gcaggcaatc gaccgcaatg gtgttgtctt accggcagtt atcactccgt
     2641 ttgatacaat aatgaaggtg actacaaaac cagtagcacc aagttcaagc acatcaaatt
     2701 caagtacaag cagttcatcg gagacatctt cgtcaacgaa agcaactagt tcaaaaacga
     2761 attaaaaata gaaaaggatt ttataacaat gggtaaatat tttgggactg atggagtccg
     2821 tggagaagct aacctagaac taacaccaga attagccttt aaactaggac gttttggagg
     2881 ctatgttctt agtcaacatg aaacggaagc gccgaaagtc tttgtaggac gtgacacacg
     2941 tatttcaggg gaaatgctgg aatcggcctt ggtggcaggt ctcctttcag tagggattca
     3001 cgtatacaaa cttggtgtcc ttgcaacacc agcagtagct tacttggttg aaactgaagg
     3061 agcaagtgcc ggtgtcatga tttctgctag ccacaaccca gcccttgata acggaatcaa
     3121 gttctttggc ggtgatggct tcaaactaga tgatgaaaaa gaagcagaaa ttgaagcctt
     3181 gctagatgct gaggaagaca ctcttcctcg tccaagtgca gaaggcttag gaattttggt
     3241 agattatcca gaaggcttgc gtaagtatga aggatacctt gtttcaactg gaactcctct
     3301 tgatggaatg aaggttgcct tggatacagc taatggagca gcttctacca gtgcccgtca
     3361 aatctttgca gaccttggtg cccaattgac ggttatcggg gaaacaccag acggtcttaa
     3421 catcaacctt aatgttggtt caacacatcc agaagccctt caagaagtgg tcaaagaaag
     3481 tgggtcagct attggtttgg cctttgatgg agacagtgac cgcttgattg ctgttgatga
     3541 gaatggtgac atcgtcgatg gtgacaagat tatgtacatc atcggaaaat acctttctga
     3601 aaaaggacaa ttggctcaaa atacaattgt gacaactgtt atgtctaacc ttggtttcca
     3661 caaggccttg aatcgcgaag gtattaacaa ggcagttact gcagttggtg accgctacgt
     3721 tgttgaagaa atgagaaaat caggttacaa ccttggtggt gaacagtctg gtcacgttat
     3781 cttgatggat tacaatacca caggtgatgg tcaattatca gcagttcaat tgactaaaat
     3841 catgaaggaa actggtaaga gcttatcaga gttggcggca gaagtaacga tttatccaca
     3901 aaaattagtt aatatccgag tggaaaacgt catgaaggaa aaggccatgg aagtgccagc
     3961 tatcaaggcc atcatcgaga agatggaaga agaaatggcg gggaacggcc gtatccttgt
     4021 tcgtccaagt ggaacagaac ccctcttgcg tgttatggca gaagcgccta caacagaaga
     4081 agtagactac tatgttgata ccatcacaga tgtagttcgt gctgaaattg ggattgacta
     4141 aatcctagaa aactagatga aaataaaaaa ttatggtaca atagcttata atattgtagc
     4201 cgatggagaa agacatgaat cttaaacgtg aacaagaatt tgttagtcag tatcattttg
     4261 atgcgcgtaa ttttgaatgg gaaaatgaaa atggagctcc tgaaaccaag gtggatgtga
     4321 atttccaatt gctccaacat gaccaagaaa atcaagtgac ttccttgatt gtcatcttga
     4381 gctttatgat tgtatttgat aagtttgtta ttagtggaac aatctcacaa gtaaatcata
     4441 tcgatggccg tattgtcaat gaaccaagtg aattgaacca agaagaggtg gaaaccttgg
     4501 ctcgtccatg tttgaacatg ctcaatcgtt tgacttacga agtgactgaa attgcattag
     4561 acttaccagg aattaatttg gagttctaat atgaaattag ctgttttcac agattcctct
     4621 gcttatctca gtgcagagac cttgcaaaga gaagacttgt ttgtcttgga tattcctgtc
     4681 aatattgatg gtgaggaata tgtcgaaggc atcaatctgt ctgctgagga attttaccaa
     4741 aaaatggctc aggcttctga attgcctaag accagtcaac caagtattgc caagttagat
     4801 gagatcttaa cttcgctcaa agaacaaggc tatacacatg ccttggggct tttcctatct
     4861 tctggaattt caggttttta ccaaaatatc cagtatatgg tcgatgacta tgagggctta
     4921 accattgctt tcccagacac tttgattaca agtgctcccc taggcatcat ggttgaaagc
     4981 gtctttaatt ggcgtgatca gggcgatgat tttgccagca ttcaggataa gctagccatt
     5041 caaatcagcc gtacgtcagc ctttatcatg gtcgatgact tggatcattt ggtaaaaggt
     5101 ggacgccttt caaatggggc tgccattttg ggcaatttgc ttagcattaa gccaatcctt
     5161 tattttaacg atcaaggtgt gattgaagtt tacgaaaaag ttcgtactga aaagaaggcc
     5221 accaagcgct taattgaaat tatcaaggaa acaacggctt caggtcaata ccgggtcatt
     5281 gtcattcatg ggaatgctcc tgaaaaggct gaagaattgc gtcagcactt gcttgatttt
     5341 ggcttgggtt cggatgtttc acttgctaca tttggtagtg tcattggaac gcacctagga
     5401 gcaggaagta ttgctctggg ttatattcca gtgatttagt tggcgcttct aggctagtta
     5461 agatgccttg tatcttagaa attgaacacg cctggaaccc tgtgtgaaaa agatagttct
     5521 tccaagaagt agacacttct tgattggaat tcctattttc actttgtgtt cttacggact
     5581 ttgtatctta gacaggagta gagatgagta ttcgagtaat tattgccggt tttaagggaa
     5641 agatgggcca ggctgcttgt cagatggtat tgactgatct agacttggac ttggtggcag
     5701 ttttggatcc ttttgagtct gagtcagaat ggcagggtat tcctgttttc aaggataagg
     5761 ctgatttagc tggttttgaa gcggatgtct gggtagattt tactactcca gctgttgcct
     5821 acgaaaatac acgttttgct cttgaaaatg gctttgctcc agtagttgga acgactggtt
     5881 tcacgagtga agaaattgca gagctaaaag aattttctcg tgcccaagac ttgggtggcc
     5941 tgattgcccc taactttgcc ttgggtgctg tcttactcat gcaatttgcg acgcaggctg
     6001 ccaaatattt cccaaatgtg gagattattg agctccatca tgacaagaaa aaggatgctc
     6061 cgagtggaac agccattaaa acagctgagt tgatggcaga ggttcgagag tccattcagc
     6121 aaggcgcagc agatgaggaa gagctgattg ctggtgctcg tggtgctgac tttgatggta
     6181 tgcgcatcca ctcagttcgt ttgccaggct tggtagctca tcaagaagtc atctttggca
     6241 atcagggaga agggttgacc ctccgtcatg actcctatga tcgcatctcc ttcatgacag
     6301 gagtcaattt gggaattaaa gaagttgtca agcgtcatga gcttgtctat ggattagaac
     6361 acttattatg agattaacgc aaatgccttc tgaatttcag aaggctttac cagtattaga
     6421 aaaaattaaa gaagcaggct ttgaggctta ttttgttggg ggctctgttc gagatgccct
     6481 tctccatagc cctatccacg atgtggatat tgcgacgtct tcttatccag aagagaccaa
     6541 gcagattttt ccgcgaacag ccgatatcgg aatcgagcat ggaaccgtct tggtcttaga
     6601 tggggatgag gagtatgagg taacaacctt tcggacagag gatgtctatg tggactatcg
     6661 cagacccagt gcggtttcct ttgtgcgctc gctagaagaa gacctcaaac gccgtgattt
     6721 cacagtcaac gcctttgcct tggatgagac aggagaaatc gttgacttgt tccatggttt
     6781 agaagatttg gaaaagcaag tcttgcgagc agttggagtg gctagtgagc gtttcaacga
     6841 agatgcttta cggattatgc gtggtttccg ttttcaggct agtcttggtt ttgcacttga
     6901 gccagaaaca tttaaagcta tgaagacctt gacgccgctt ttggagaaaa tttctgtaga
     6961 gcgtaccttc gtcgagtttg ataaactctt gctggctcca ttttggagaa ggggcttggc
     7021 ttccatgatt gagagtcaag cttatgacta tctccctgat atggcatcta gccaggacaa
     7081 gctcaacaga ctgtttgatt tggagactga ttttactttt gaatcctctg aacaagcctg
     7141 ggcggcttta ctatgggctt tggagattga aaatgcgcag tcatttttga aatcttggaa
     7201 gacctcacgc cagtttgcca agcaagttca ggatttgctg attattttgg ctctgcgtga
     7261 aaatggagaa ttgagcaagc gagattgtta tcgctttgat atagatttgc ttttacaggc
     7321 tgaaaatctt cgtcaagctc aaggaaaaga agtcaaccta caagccatca caaaaaaata
     7381 ccaaagcttg actatccatg acaagaaaga gattcagatt aatggcgata ttttgatcaa
     7441 ggaatatggc tatcagccag gcccagactt gggagagatt ttaacagaga ttgagtttgc
     7501 cattgtcgat ggagaattgg agaataatcg tgaagccatc catgcttacc tgagggagaa
     7561 aaaatgagtg attttattgt tgaaaaacta agtaaatccg ttggtgacaa gaccgttttt
     7621 agggatattt cctttattat ccatgactta gacagaattg gtttaatcgg tgtcaatggg
     7681 actggcaaga ccaccctttt ggacgtcctt tctggtgttt ctggatttga tggggatgtc
     7741 agtccttttt cagctaaaaa tgattaccag attggttact tgactcagga tcctgatttt
     7801 gatgatagaa agacagtttt ggatacggtt ctatctagtg aactcaagga aatccagctc
     7861 attcgtgagt atgaattgat tatgctcgac tatagtgagg acaagcaggc gcgtttggaa
     7921 cgtgtcatgg cagagatgga ctctctccaa gcttgggaaa tcgaaagtca ggtcaagacc
     7981 gttcttagca aattgggcat tcaagactta tctactcctg ttggggaatt gtcaggtggt
     8041 ctgagaagac gggtacagtt ggcacaagtc ttacttggca accacgacct cttgcttttg
     8101 gatgagccga ccaaccatct ggatattgcg attattgagt ggctgaccct ctttttgaaa
     8161 aattctaaga agaccgtcct ttttatcact cacgatcgtt atttcttaga cgctttgtca
     8221 acacggattt tcgagttgga tcgtgcaggc ttgaccgagt accagggcaa ttaccaggac
     8281 tatgttcgcc taaaggcgga acaggatgag cgcgacgcgg ctcttcttca caaaaaagaa
     8341 caactctaca aacaagaact ggcctggatg cgcagacaac cgcaggcgcg tgcgaccaag
     8401 cagcaggccc gtatcaatcg attccatgat ctgaaaaagg aagtttcagg cagtagtgct
     8461 gagacagact tgaccatgaa ctttgaaacc agtcggattg ggaagaaagt catcgagttt
     8521 caggctgttt cctttgccta tgaaaacaag cctattttgc aagattttaa tctcttggtg
     8581 caggccaaag accgtatcgg aatcgttggg gacaatggtg ttggaaaatc aaccctgctc
     8641 aacttgattg caggaagtct tgagccaact aaaggacaag ttgtgattgg ggaaactgtt
     8701 cgcatcgcct atttctctca gcaaattgag ggtttggatg aaagcaagag agttatcaat
     8761 tacctgcagg aagtggcaga agaggtcaag accagtggcg gttctacgac ttcgattgca
     8821 gagttgctgg agcagttcct tttcccacgt tcgacgcatg gaaccttgat tgagaaattg
     8881 tcagggggtg agaaaaaacg tctttatctc ctcaaactgc ttttggaaaa accaaatgtt
     8941 cttcttttag acgagccaac caatgaccta gatattgcaa ctttgacagt cttagagaat
     9001 ttcttgcaag gttttgcagg tcccgtttta acagtcagtc acgaccgcta tttcttggat
     9061 aaggtagcga ccaagattct cgcttttgag gatagcaaga ttcgtccttt ctttggtcat
     9121 tacaccgact atcttgatga aaaagctttt gaaacagata tggccaatca agtgcaaaag
     9181 gtcgaaaagg aaaaagtggt caaggttcga gaagacaaga aacgtatgac ctaccaagaa
     9241 aagcaggagt gggcaagtat tgaaggtgat attgaaacct tggaaaaacg tatcgctgct
     9301 attgaagagg aaatgcaggc taacggctct gactttggta agctggctac tctccaaaaa
     9361 gaattggatg agaaaaatga agcactcctt gaaaaatacg aacgctatga gtatctcagt
     9421 gaatttgata gttaagacta ttcgaaaatc aaagtgcaaa ctatgtcggc ttcacattgc
     9481 cgactcaagt acagcctgtg accggcttcc taatttgcac tttgattttt attgagtata
     9541 aaagaataga aaaatcccgt ctcatgaaag gatttctcta ttcttttttg gtttcttgat
     9601 gaaagatatt ttgccaggtt tcgtggcgac gccagatact ggtatggatg ataccatcta
     9661 actcatagca gatgagtttg gttttttgac tgatggaagt aatttgaatg tccttgatag
     9721 cagaatttaa ctcttttttt gtcttataag cctctttatc catctgctct ccatcttggc
     9781 gaatatagac aaaatcatca gtcaagagtt cttctagttg gtttccttgg tcaatcaatt
     9841 gttcacgcat aagcaatttt ttatagacat tgtctaaaat ttcatcctca gggataggtg
     9901 ctggttcgat atggacatcg gtatcaaaga cgccaaaacg ctcctccagc atagactcga
     9961 cctgatccgc gatttcatgg ctttcaaaaa cagacaagtc aggattcatc tctagtgtaa
    10021 tatccaggta gatgttgcta ccgtaggtgc gacctctttg cgatttgacc ttgctgattt
    10081 tgggaatttc catgatagcc ttttggtagt cctcgagcag gcggtcgtca aagccatctg
    10141 aaagactaaa ggaagactcg atgaagatat cataggcagt cttcaagata aagaaagtga
    10201 tgatgatagc aaccagttta tccacaatcg gataattgaa actactagct aggatggcaa
    10261 tggcggttcc aagtgaggta acagcgtcag aaagattgtc cttagcagct gccttcagcg
    10321 ccttggagtt ggatttctta ctgaggcgag tattgtagag atagaccaca aacataatcg
    10381 ctgcagaaat gattcctaga gttgcaccaa gaggatcaat gaccgtttct tcccgactga
    10441 gaatcttttg aatggtatct cttagaacat cgaaaccgac atagaacatg atgatagaag
    10501 tgatcaagct tgccaaatct tcaatcttcc aatgaccaaa acggtggtca cggtctgcag
    10561 gctggcgcgc catccgaatc ccgattaaga gggccacatt tccaatgatg tccgatacgt
    10621 tattaaaacc atcggccacc aaactggatg aatgaaggag atgaccagtt gctaatttgg
    10681 ctgcagacaa gatcaaatag gtcgaaatac tgataatggc tccacgctcg gctaacttga
    10741 gatttgagat agattgcttc attcaacttc ctttctagtc acatagcatt ctaccattat
    10801 actggttttc aaggaaaaat tcaaataagg cagtttttat tctttgaaaa ctccccaaaa
    10861 tttggtataa tggtactact caagggagta gctggcagaa acctgtgata gtgtcgtcat
    10921 tccgaatttt atgctgaaaa gtatgctttc cggccctatc ttaaacagcg agacttgtta
    10981 tgattaacag gtctcttttt gtttgtcgtg aaaagatatg acagaaagag agtctgtttt
    11041 gcacacaatg tcaaggagga gacacatgtc aaaagaacaa aaacgccaag cgttttatac
    11101 tcagagccct gaagaggtct tgcaggctgt ggatgcgacc gagcaaggtt tgtcatcaag
    11161 tgaggcggaa aagcgccttg ccgaatttgg gcacaatgaa ctcgaagaag gcgagaaacg
    11221 atcaatcttg gtcaaattca tcgagcaatt taaggatttg atgattatca tcctagttgc
    11281 ggcagcaatc ttgtcagtcg tgacttctgg tggggaagat atcgcagatg ccattatcat
    11341 cctagctgtg gttatcatca acgctgcctt tggtgtttac caagaaggaa aagctgaaga
    11401 agctattgaa gccctcaaat ccatgtctag tccagttgcc cgcgttcttc gtgatggaca
    11461 catggcagag attgactcta aagaattggt accaggcgat atcgttgccc ttgaagcagg
    11521 tgacgtggta ccagcggacc tacgtttgat agaagccaac tctcttaaaa ttgaagaagc
    11581 agccttgaca ggtgaatctg taccagtcga aaaagacttg tcagtcgagc ttgcgacaga
    11641 tgctggtatt ggtgaccgtg tcaacatggc cttccaaaac tcaaacgtaa cctatggtcg
    11701 tgggatgggt gttgttgtca atacaggtat gtacactgaa gttggtcata ttgctggtat
    11761 gcttcaagat gcggatgaga ctgatacacc actcaaacaa aatttgaaca acctttctaa
    11821 ggtcttgacc tatgctatct tggtcattgc ccttgttact tttgtagtgg gtgtcttcat
    11881 tcaagggaaa aatccacttg gtgagttgtt gacttctgtt gcccttgccg ttgcagccat
    11941 tccagaagga cttcctgcta tcgttaccat cgttctttct cttggtactc aagttttggc
    12001 caaacgacat tccatcgttc gtaagttgcc agcagttgaa acacttggtt caactgaaat
    12061 catcgcttct gataagactg gtacgctgac tatgaacaag atgacagtcg aaaaagtctt
    12121 ctacgatgcg gttctacatg actcagctga tgatattgaa ctaggtcttg aaatgccact
    12181 acttcgttca gttgtcttgg ccaatgatac gaaaatcgat gtggaaggta acttgattgg
    12241 tgacccaacc gaaacagcct ttatccaata tgccttggac aagggctatg atgtcaaagg
    12301 tttcttagag aaatatcctc gtgtagctga attgccattt gactctgacc gtaagctcat
    12361 gtcaacagtt cacccattgc cagatggtcg tttccttgta gcagtcaagg gtgcgccaga
    12421 ccaactctta aaacgttgtc ttcttcgtga taaggctggg gatattgctc cgattgatga
    12481 gaaggttaca aatctcattc atacaaacaa ttctgaaatg gctcatcaag ccttgcgtgt
    12541 ccttgcaggt gcttataaga ttatcgatag tattccagaa aatctcactt ctgaagagct
    12601 tgaaaatgat ttaattttta ctggtttgat tgggatgatt gaccctgaac gtcctgaagc
    12661 cgctgaggct gttcgtgtgg ctaaggaagc gggaatccgt ccaattatga ttacaggtga
    12721 ccaccaagac acagcggaag ccattgccaa acgtttggga atcattgacg caaacgatac
    12781 agaaggtcac gttttaactg gtgctgaact caatgaactg tcagatgaag aatttgaaaa
    12841 agtcgttggt caatactctg tttatgcccg tgtgtctcca gaacacaagg ttcgtatcgt
    12901 caaggcttgg caaaaacaag gtaaagtcgt tgccatgaca ggtgacggtg tcaatgacgc
    12961 gccagctctg aaaacagccg atatcggtat cggtatggga atcactggta cagaggtttc
    13021 taagggggct tctgatatga ttcttgcaga tgataacttt gcgactatta tcgtcgcagt
    13081 ggaagaagga cgtaaggtct tctcaaacat tcaaaagact attcagtacc tactttctgc
    13141 taatactgct gaagtattaa ccatcttcct atcaaccttg tttggttggg atgtcttgca
    13201 gccggttcat cttttgtgga tcaacttggt aacggatacc ttcccagcta tcgctcttgg
    13261 tgttgaacct gcggagcctg gtgtcatgaa tcataaacca cgtggacgca aggcaagctt
    13321 cttctcaggt ggtgttttga gttctatcat ttatcaaggt gtactccaag cagctcttgt
    13381 tatgagtgtt tatggccttg cgattgctta cccagttcat gtgggtgaca atcatgctat
    13441 tcatgcagat gccctaacga tggcctttgc aacccttggt ttgattcagc tcttccatgc
    13501 ctacaatgtc aagtctgtct accaatccat cttgacagtt ggcccattca agtctaagac
    13561 ctttaactgg tccatcttgg tatcttttat ccttctcatg gcaacaatcg ttgtagaacc
    13621 gcttgaagga atcttccacg taaccaaact agacttgtca caatggggga ttgttatggc
    13681 tggaagcttc tcaatgatta tcatcgtcga aatcgttaag tttattcaac gcaaactcgg
    13741 ttttgacaag aatgcgattt aagggaggtt tcggatgtca gcatatcaat taccgaccgt
    13801 atggcaggat gaagctagta atcaaggagc ttttacgggg ctaaacagac caacagcagg
    13861 tgcccgtttc gaacaaaact tgccaaaagg agaacaagct tttcagcttt attcactggg
    13921 aacaccaaat ggtgtgaagg ttactatctt attggaagaa ttactagaag ctggttttaa
    13981 ggaagcggct tacgacttgt ataagattgc tatcatggat ggggatcaat tcggctcaga
    14041 ctttgtgaag ctcaatccaa attccaagat tccagcctta ttggaccagt caggtactga
    14101 aaacgtaaga gtctttgagt ctgctcatat tcttctttac cttgctgaga aatttggagc
    14161 ctttttacca agtaatcctg tggaaaaggt agaagttttg aattggctat tctggcaagc
    14221 aggtgcagca ccttttctag gtgggggatt tggacatttc ttcaattatg ctcctgaaaa
    14281 attggaatat cctattaacc gttttacgat ggaagtgaaa cgccagttgg atttattgga
    14341 taaggaattg gctcagaaac cttatattgc aggcaatgac tatacgattg cagatattgc
    14401 tatctggtct tggtatggac agttagttca aggaaatctt taccaaggtt ctgcaaaatt
    14461 cttggatgcc tcaagttatc aaaatctagt aaaatgggca gaaaaaattg ccaatcgtcc
    14521 agctgttaag cgtggcttgg aagtaactta tacagaaatt aaatagcaaa aaagtcatct
    14581 tcggatggct ttttgctaca gttgagggaa agggtttgca gttatcggct tttgtgctat
    14641 aattgctata atatagtaaa aagcaagagg agtgtgagga agtggaaaag aaaattgtga
    14701 aggatatctt atttttatct caagtgtctc agccggcaag tcaggaggac ctttatcttg
    14761 ccagagattt gcaggataca ctcttagcaa atcgtgatac ctgtgttggt ctagctgcca
    14821 atatgattgg ggtgcagaag cgcgtgatta tctttaatct tggcttggtt cccgtggtca
    14881 tgtttaaccc agtgcttctg tcctttgaag gatcctatga ggcagaagaa ggctgtttgt
    14941 ccttggtagg tgtgagatca actaagcgtt atgaaaccat aagggttgcc tatcgtgaca
    15001 gcaagtggca ggaacagacc attaccttga caggcttccc agctcagatt tgccagcatg
    15061 agctggatca cttggaagga cgaatcattt aggaggaaag caaatgaaac gaatagtctt
    15121 tgaacttatt tttatcgcaa cgacctggta tatcttttta ccgcccctta acctgaccag
    15181 ctgggaattt ctcttcttcc tctgtgggca tttgttagtt gtggcaatct tatttggctt
    15241 tggcaagggg ataaaccttg tcaaaacggt tcatgtgcgc cacggtaagg cggaagctgc
    15301 cttaaatctt gagggtttca aaatcaatcg gttagggaaa attctgttag cttcgattgg
    15361 aggaattctt ctcttggcag ctttggtttc cttggtaact tccagcatgt ttcaggctaa
    15421 aaattatgcc aatgtagtca cggttacgga aaaagacttt actgaatttc ctaagagtga
    15481 caccagtaag gttcctatcc tagatagaag tactgctgaa aaaattggag accgctactt
    15541 gggttcccta accgataagg tgtcgcaata cgtagcggca gatacctata cccaattgac
    15601 aattgatggg aaaccttatc gggtcacacc actagaatat gcagacccta tcaaatggtt
    15661 taacaatcaa gccaagggaa tcggtgagta tatcaaggtg gacatggtaa ctggaaatgc
    15721 ggatttggtg gacttgaaga caccaatcaa gtattcagac tcggagtatt ttaaccgtga
    15781 tgtcaaacgt cacctgcgct tgaagtaccc gaccaaaatc tttaaaactc catcttttga
    15841 ggtggacgat gagggcaatc ctttctatgt agcaacggtt taccaaaagc aatttggact
    15901 tgctgttcct cgtcctgctt cagtcattat cttggatgct acaaatggag aaaccaagga
    15961 atacagctta tcagatgttc cagaatgggt ggacaggatc tatccagcag aggaaaccat
    16021 tgagcaaatt aactacaacg gcaagtacaa ggacggtttc ttgaatgcca tgatttccaa
    16081 gaaaaacgtg acccagacta ccaagggcta taattacttg tctatcggta atgacatcta
    16141 tctctacaca ggtgtgacgt cggctaatgc ggatgagagt aatcttggtt tcatccttga
    16201 aaatatgcga acaggagaaa tcactaagta tagcttggct tctgcgacag aagaatcagc
    16261 ccgtgaatca gcagaaggtg ctgttcagga gaaatcctac aaagcaacct tcccaatcct
    16321 catcaacctc aatgacaagc ctctctacat catgggctta aaggacaatg ctggcttggt
    16381 caaagagtac gccctggtag acgcagtcga gtaccaaaat gttatcgttg ctactacagt
    16441 ggaagagatg ctcagcaagt atgccaataa aaacgacctt gaaattgaca atgcaacgac
    16501 agaaagcatc aagggagtag tagcagacct caaatcagct gttatcaagg gagacactgt
    16561 ctacttcttt aaagttgatg gcaagatata caaggtcaag gcttcagtat ccgatgatct
    16621 tccttacctt gaaaatggta aaaccttcga aggtcaagta ggaaaagaca attatctcaa
    16681 gacctttaag ctacggtaaa aataggtttt ttcagaaagt atatgttata atagagtaaa
    16741 ttaagactaa tggaggacaa agaaatgggt ttttatttga tggttgcttc aatgctactc
    16801 ggactgctcg ctttgaagat aggtttttct cagttcaagg agaaaaaaga taaattctta
    16861 tctatcttaa caagtttagc tggcacagcc cttgttctcg tggctgtctg gttaggatgg
    16921 cccaaataaa tagaaaaacc tcggtcaaac cgaggttttt caaatgaatt tcttggttgt
    16981 ggctaaaaaa tatgctacac tatcaatatg aaaattttaa tcccaacagc aaaagaaatg
    17041 aacacagact tgccaagtat cgaggcaatt cctttaaaac cagaaagtca gaccgtgctt
    17101 gatgccttgg ctctctattc tgccagtcaa ttggagagtt tctacaaggt atcagctgag
    17161 aaagcggcgg aagaatttca aaatatccaa gctttgaaaa ggcaaactgc tcaacactat
    17221 ccagccttga aactttttga tgggcttatg taccgcaaca ttaagagaga taagctgacc
    17281 gaggcggaac aagattatct tgaaaatcat gtcttcatta cctcggcttt gtacggtgtt
    17341 gttccagcct tgtcacccat ggctcctcac cgtttggatt ttttgatgaa attaaaagtc
    17401 gctggtaaga ctttgaagag ccattggaag gcagtctatg atgaagctct gaagaaggaa
    17461 gaagtgattt tctctctctt gtcatcagag tttgagactg tattttctaa ggaaatcaga
    17521 gcaaagatgg tgaccttcaa attcatggag gatagaggcg gtcagctgaa gattcactca
    17581 actatctcca agaaagcgcg cggggccttt ctaacagctt taatagaaaa tcaagtacaa
    17641 actgtggggg aagcacgtcg cttgaacttt gctggatttg tttaccgaga agatttgtca
    17701 caaccacagg gattggtttt tgtaaaggaa gtatagaaat cagataagag aaaagtcagc
    17761 acgattatgc tgactttttt gataacttat aaagtattgg acaaatgaat ctcatttgat
    17821 aaggtgttaa gatgattaac caaattcatg attgacagat gatttcggca aataaacttc
    17881 ttggtaatcc ctgaaatata gaaattagac acgatgatat cgtaatctgt ctgatttaaa
    17941 atctcaggac ttgtttttaa ttcatcccaa atatcgaagg taaagcggtt attacagtaa
    18001 taggaaagca tatcaacaaa ggtaagggat atagcatggt caaagttact gataatcaaa
    18061 accttgatag gtggtcgatt ttctaacaac tgagtagaga ggttttcagc atgggttaag
    18121 atggtgtaca tcaagtgttc caactgttca ggatggtcat gctgtccaat tgcctgacgg
    18181 tattgagcca gttcttgacg cgcacttccc ataaagtctg ggaagtaaac ttcaaatttt
    18241 ttaatcgtca atgctttttg ttcaaataag attggggtag aaaagatttc ctgtctttca
    18301 aagaaagcag tgttgtgtaa atgccaaatc agctcatcgt ggttagtaaa agtaatctta
    18361 tattgttttg ataggagttc taatatttga ctaagtaatt gataagagta tcttgcttga
    18421 ctgttatctt ctaaagagtt gaagaattct tgaggatcta ggaaaatatc attctgaaga
    18481 aaagaaataa aaatttgagc gattgtatct ggagtcattt caagcccaaa atgtttagag
    18541 aaataagcaa gtgtctcctg gaaatttgga atgctcttta aaagaggata atattctttg
    18601 taaaagtggt tggggaggtc aatgaagtga ccatttttaa ccctgtggat actgatagct
    18661 atcatcagtt tgtacattct ataaattgaa aatcgcattg gataattcgt gattttatag
    18721 aagaagtcag caaactctgt taaatcttcc tcaggaaggt caggaaaagg ccaatctagg
    18781 aaataatagc gctcagaaaa gtattgggca aaaaagtaac gaatatcgat ctcatttcca
    18841 cgtatctcgg atggagtaaa agataattca atttgaaact gagatgaaag aacctttgta
    18901 atatttctgc ccagtcgata gaggttggca ctactaaagt aaagattttc tattgttcga
    18961 taaataggta gcccctcatt gaagaacata tactctagta attgaaaaga ttgagaatta
    19021 gcaagaaaat attgataaat atcttctaca ctagtgttaa cttctaaatc tatcatgatt
    19081 ccgttaacag aagattggat gttaatagat ggaaaggcaa tacgtaattc atttaaatca
    19141 ctttttaaga ttcgttctgt acatcctaat ttttcggcta gttcatgtaa tttcatccaa
    19201 ttacgattct gaattagggt ttccattaag cgtaattgtc tttgaacttt tgtggataaa
    19261 aggtttctca tacgggtatt tcctccataa ttcattatat ctttttttgt ctaagtagta
    19321 taaaaaaatt agagcaagaa aattgtcgtt agtaatcgga aaaattagaa taatataagt
    19381 ggcttttaag tgcagaaaca gaatatatta attgttcaga aaatattgat taatgcctca
    19441 aatagttgta cattgtaaac tataaaatac tatctaggag tttaaaatga aacattcaca
    19501 taaaaaatca tttgactggt atagcatgca acaacgttat tctattcgta agtattactt
    19561 tggtgcagct agtgtcttgc tcggtaccgc tttggtatta ggtgtagcag ctagtgtcca
    19621 aacagtacaa gcggaagaaa acaaacaaga aactaccaat agtatttctg ttggtagggg
    19681 agaagcagct actaaaccag cagaggtttc tgcgtctaat aaagagaaaa cctatgcagc
    19741 tccaactgta gctaatccag tagaaacgac tccagttaaa actgaagaag ttactaaacc
    19801 agcagaaaaa gttgaagaag caaaagacaa aaaagaggaa gtaacgcatc aagatgccgt
    19861 tgacaagtca aaattattaa cggctctttc gcgtgctaaa aaattagaaa gcaagttata
    19921 tacagaagca agtgctgcta acttgcaaac aagtatccaa gctggtcaaa gcttgcttgg
    19981 gaaagcagat gcatctgaag ctgaattatc agcagcagag tcatctattc aatcatctat
    20041 tattggtcta gaacttcgtt ctaactctaa caaaggaact gtatcagaaa cgcctgtagc
    20101 aaagaaagct aatatagttg aagcgaagga agagactaat ccagctgcaa caactgatcg
    20161 ttcagctgtt gatagcgctg ttttgccaac tagcacagct gctaaagtag aaacaacttc
    20221 agctccagca tctactaatg aaatcttgaa accaggtttg agcctttctg atgctcgcca
    20281 aaatccagct atccgtaagg aagatgttga tagggggtat agtggtttta gaacagcagg
    20341 aagtggtttt agagcagctg gaccagaaaa taaaccaatc ttaaatccaa ataatactat
    20401 tgcattttct gacatcagtc agggctcaca ttcatttcgt ggtataggac attcacgtgg
    20461 tggtcgtgaa atccattatg atgtaacgac agtacgtaga ggcaataata ttaactttac
    20521 aattaattat tttgcgccag gaaatcttag agagtttgtt aataacaact ttatcttaga
    20581 taagggaaca ggttatggtg aacctacacc tgctactgtt ataacaccaa acttaagaaa
    20641 ccaagttaaa aacattagta agggtggaaa ctttgtttct cattcaggct acagtttaga
    20701 agctgcagta gaaacaaaca aaagtcaaac aattacgttt agtttaccta taactaaccc
    20761 taacggagat ttatctcttc gtttacgtcc agttgaattt aacgtagacc aaggtggtag
    20821 tggaactggg actagtaatg atccatatag taattctaac tattattttg aaacggatcc
    20881 attgtatcta gatgcaaatc caaatcaagc taatccttta acaacaagtt ttaatactaa
    20941 agttgatttc caaactttat atataccaac tactaaatta gcagaaggag taacggagtt
    21001 agtttctgaa ggggtagaag gagagaaatc acaagcatac agacttcata aatttggaga
    21061 tcagtatgtt ttaggacttc ctgtagggaa tgctactaca gttacagctg ctaaacctcg
    21121 tgtaatgaaa tacggtattg gtaaaattgc tgcaactcaa aataaaacag gggatacgaa
    21181 tcacattaaa ttttatttag ataaagatgg tgatggtgtc tttaataatc aagatgaagt
    21241 aattttaaat acagatatta aagatggaga aagagggcca acaggtgcaa ctggggcaca
    21301 aggaccagca ggaccaaaag gagcagatgg acaaagagga ccagcgggac cacaaggacc
    21361 aaaaggagaa caaggtaatc caggaactcc aggtaaagat ggaaaatctc taattgctgt
    21421 taaaaatgga actgaaacaa aagtctatgt agaggatccg gctagaccag gacaaccact
    21481 taatccaaac caaccattag caactatcac tgatggaaga aacggtacta atggacaatc
    21541 accaacaatt acagcgacac gaagtgtgca aaatggcaaa aatggtgtat tagtaacaat
    21601 tacaccagta gaaggtcgtc cacaaacaac atttgtagag gatggacaaa agggtgctga
    21661 tgggaaaact ccaacagtaa caataactga ggggcaaaac ggcacacata cattaacggt
    21721 tcataatcca ggaagtccag atgtgacaac tacgatccgt gatggagcta caggacaagc
    21781 aggtcgtgat ggtaaagatg tattaaacgg aaaagtaaat ccacaaccaa accaaggtaa
    21841 aaatggagat aaatatatta ataccgaaac cggtgatgtc tatgttaaaa acaatggaaa
    21901 ctgggataaa gaaggcaaca tcaaaggccc taaaggtgac aaaggtgcag atggtgctaa
    21961 aggcgaaaaa ggagaccaag gcgaacgcgg cctaactgga gcgcaaggag ctaaaggtgc
    22021 ggatggcgca gtaggtcgtg atggacgtga cggtaaagac gtgttgaacg gcaaagctaa
    22081 cccagaagca catcaaggta aagacggcga taaatacgtt aatacagaaa caggcgacgt
    22141 cttcgttaag aataacggca actgggataa agagggcaac atcaaaggcc ctaaaggtga
    22201 caaaggtgca gatggtgcta aaggcgaaaa aggagaccga ggcgaacgcg gcctgactgg
    22261 agcgcaagga gctaaaggtg cggatggagc agcaggtcgt gacggacgtg atggacgtga
    22321 cggtaaagac gtgttgaacg gcaaagttaa cccagaagca aatcaaggta aagacggcga
    22381 taaatacgtt aatacagaaa caggcgacgt cttcgttaag aataacggca actgggataa
    22441 agagggcaac atcaaaggct ctaagggtga caaaggtgaa cgcggagaag atggtaagac
    22501 tccagaagta actgtaactc caggtaaaga tggccatagt actgacatta cattcactgt
    22561 tccaggtaaa gatccagtta cagtaaatgt taaggacgga gaaaatggtc tgaacggtaa
    22621 aactccaaaa gttgatttac ttcgtgtcca aggaaaaaac ggaaatccat ctcatacaat
    22681 tgtgacattc tatacagatg aaaacaatga cggcaaatat acaccaggaa ctgatgaact
    22741 tctaggttca gaaatgatta aagatggtgc taaaggcgcg gacggacgag atggtaaatc
    22801 attgcttact gtcaaggatg gtaaagaaac taaagtttac caagaagatc cagctaaccc
    22861 aggacaacca ttaaatccag aaaaaccact tgcggtaatt agagatggag tagatggaaa
    22921 atcacctaca gttacagctg ttcgtaaaga tgaagcaggg cataaaggtg tagaaatcac
    22981 tgttgataac catgatggtt cacaaccaac tacagtcttt gttcaagatg gtgctaaggg
    23041 agaaactggt gcaaccggtc aggatggaca aactcctaca atcactactc aacgtggaca
    23101 agatggccaa agcactgttg taactatcac aacatcaggt aaagatccag taaccttcac
    23161 tgtaaaagat ggtaagaatg gtaaagatgg ccgtgcaccg aaaatcaaag tagaagatat
    23221 tacttcacct tcaagaatta gacgcgatac agatgctgct gcaactccaa cgcgtaacgg
    23281 tatccgtgtt acagtttatg atgatgttaa tgacaatggg gtatacgacg aaggtgtcga
    23341 taaagtatta aatagtaaag atatttataa cggtatagat ggacgtgatg gttcagctcc
    23401 aactattact acaaaagata atggagatgg aactcacact atcacagttc aaaacccaga
    23461 tggttctgaa tcaacaacag ttgttaaaga tggtaaagac ggtaaaactg cgaatatcac
    23521 tacaacagaa aacccagatg gaagccacac aattacggtg acaaatccag atggttcaac
    23581 taaagaaact gttgttaaaa acggtaaaga cggtaagact cctaaagttg aagtaacgga
    23641 taacaacgat ggaactcata ctgttaaagt tacagatgga gacggcaatg ttaccaacgc
    23701 tatcatcaaa gatggtaaag acggtaaagc tgcaacagca acaactactg aaaatccaga
    23761 tggaagccac acagtaacaa tcactaaccc agacggaact aagaatgagt ttgttgttaa
    23821 gaatggacgt gacggtgttg acggacgtac tccaaccgca tctgttcgtg ataatggaga
    23881 cggaagtcat acaatcgtta ttacaaatcc agaaggtgtg acaactgaaa ccacagttcg
    23941 tgatggtaaa tcaccaaaag tgactataac tgatgaacaa aatggaactc ataagatctc
    24001 tgttctaaat ggtgacggaa caactactga aacaatcatt aaagatggta aatcaccagt
    24061 agcaacagtt agagataacc aagatggtac ttacactatt cgtgtggaaa acggtaatgg
    24121 tactgtttct gaaaccacag ttcgtgacgg taaatcacca actgctaagg ttgtggataa
    24181 tggagatgga actcacacta tcacagttgt gaactcagac ggaacaacta caacaactac
    24241 agttcgtgat ggtagagaac caaaacttga agttattgat aacaacgatg gttcacacac
    24301 tattaaagtg acaggtgctg atggtaaagg aacgacaact acaatctttg atggtaaatc
    24361 accaaaagcg aacatcgttg ataacggaga tggaactcat acattaacaa tcgtagattc
    24421 tgatggtcgt gaatacaaat ctattatcaa agatggtaaa gacggcaaag atagcgtttc
    24481 accaactgta actgttaaaa ataataacga tggaactcac gttgttacaa tcactaatcc
    24541 agatggaagt aagacagaaa tggtgattaa agacggtaaa gatggtaaat caccaaaagt
    24601 ttctgttgaa gataatggtg atggtagtca tacaatcaca atcatcaatt ctgatggaac
    24661 tgtgacaaaa acagttatta aagatggcaa agatggtaga gatggacgtg atggtcgaga
    24721 cggcaaagac ggtaaagatg gaaaatgtgg atgccaagac aaaccagtaa caccatcaaa
    24781 tgacaaacca gttcctccaa caccaaatgt gccgacacca gaagtaccgg ttaaaccagt
    24841 accagcggtt ccagaacaac cagtagtacc aacaccggct caaccagcaa ctccagtaaa
    24901 tgctaaccca gtagcaccaa ctacaggtaa agaaaaccgt ggggacaaat tacctgaaac
    24961 tggaagccaa tctgattata tctctgttct tttaggtagc ggtattctat tgagcctata
    25021 tgtaggacga agaaaagaag attaatcagc caaaagcagt cactaatttc tcgaaagaag
    25081 atgataagtg atagatctcg aatgaaagaa tattcttaga atgattttcc tatgatggaa
    25141 aagactgcta aaaaccttga gtggtaacgc tcaaggtttt tttgggatgg ctgatgtttg
    25201 tctgaaaatc ttgattgaga aataaaaagc caccctatta ggtggctata attgatttag
    25261 actttctaaa attttctatt ttttactgaa tcgcttcgac caagtcttga gcttgttttt
    25321 caagtgagtt taggactgtt tcttcaagaa ccaattttcc gtctgcccag gcagagtcat
    25381 taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg gataaatggc aagaggtctt
    25441 tgtagatagc gaaaagttga tcgtgccctg cattggctac agatgatact gtgacaaact
    25501 tgtcttgaag ggcagaaacg ccacgtgtat cagacaagtc aagggcacga gatagccagt
    25561 caagcaagtt tttcactgta ccagggatag agaagttgta gactggagag aaaatccaga
    25621 tagcatccgc aacgagaact gcttcacgag cagcagctac agctggatgt gttggaactt
    25681 ccaaatcttg gctgaagaga ggaagggctg aataatcaag gtagctaact tccgctttac
    25741 cagcaagtgc tttctcagct tcgagcgcca tttggtggtt gaaagaacct tgacgtagtg
    25801 atccgacgat aaataatact tttttagaca tgatgtgtct cctttttctt aaaatttcga
    25861 gaactctctc gttgttataa aatatattac aacaaaacaa aagaacttgc aagaaatttg
    25921 ctcagagttt atttgaaaat tgtaaaattt cggaaactct aatcatttgt gactgaaaaa
    25981 gtaagaactg tttcactttc aaaatcggtt ttgtttgaag ggagaaatag aattggttgc
    26041 tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg tttgaagaga ttttcgaaga
    26101 gtattcttat attcacttgt aataaagctt aatagatggt aaaatagacg agtgaaaaaa
    26161 agacaaaaca aagcaaaaaa taatctactg tggcagtatg gtctagggat gacgattttg
    26221 tttgtggtta tcagtggttc ctttctgtat atggtttctc ttagcatgaa accctatcaa
    26281 acagctaaaa gtgaaggaga aaaattagct cagcagtatg caggattaga gcaggctgat
    26341 caggttgatt tatacaatgg cttggaatct tattacagcg ttcttggtcg taacaaacag
    26401 caagaagcgc ttgctgtcct gattggtaaa gatgaccata agatttacgt ttatcagcta
    26461 aatcagggtg tttcacaaga aaaagcagaa acggtttcta aggaaaaggg agctggcgag
    26521 attgacaaga taacctttgg ccgttatcaa gataagccaa tctgggaagt taagtcagga
    26581 tctgattttt atctagtaga ttttgaaaca ggagcattgg tcaacaagga gggcctatga
    26641 aactatccaa ccgtgtttta gaaatggaag aaagtgtgac tttggctgct ggagcccgtg
    26701 ccaaagcact gaaggctgag ggtagagata ttttgtctct aaccttgggt gagccagatt
    26761 tcactactcc caaaaatatc caagatgccg ccattgcatc gattcgagat gggcgtgctt
    26821 ctttttatac agtaacctca ggtctgccag agcttaaggc ggtggtcaat agctactttg
    26881 agcgctttta cggctattct gtagcgtcaa atcaagtgac agtcgctgcg ggagccaaat
    26941 attctctcta tagcttcttt atggctgtgg tcaatccagg tgatgaagtc atcatcccaa
    27001 ccccatactg ggttagctat ggagatcagg tcaagatggc agaaggcgtt cccgtctttg
    27061 tttctgctaa ggaagacaat cactttaagg tgaccgtaga gcagttagaa gcagctcgca
    27121 ctgacaagac caaggttttg gtgctgaatt cgccatctaa tcccacaggt atgatttaca
    27181 cccgtgagga actcttggca attggaaact gggctgtaga aaatgatatt ctcatcctag
    27241 cagatgatat ctatggccgc ttggtttata atggtcatga gttcacaccg atttctagcc
    27301 tatcggaagc gattcgcaag caaacagtgg tcatcaatgg tgtgtctaaa acctatgcca
    27361 tgactggttg gcggattggt tatgccgttg gagaagcaga cattatcgct gccatgtcca
    27421 agattgcagg tcaaacaact tcgaatccgt cagcagtagc ccaatatgca gcagttgagg
    27481 ctctatcagg tgagcaagat actgtagaaa gcatgcgtca ggcctttgag gaacgtctta
    27541 ataccatcta tcccctcctt gcagaggtgc caggatttga agtggtcaaa ccacaagggg
    27601 ccttctatct cttcccaaat gtcaaaaagg ccatggagat gaaaggctac acggatgtga
    27661 cagactttac aactgttatc ttagaagaag ccgaagtggc cttggtaaca ggagctggat
    27721 ttggagcacc agaaaatgtc cgcctcagct atgcgacaga cctagacacg cttaaagaag
    27781 cagtcgaacg cttgaaagca tttatgggta gtgagaatga ttgatcattt tgagattaag
    27841 gtaaaggatt tacaaatttc agaaggattt tataggagtt ttctcgttcc tttggactat
    27901 aaattggctt ttaagactag ttctctaatt agttttctat ccccgaacag ccctcatcct
    27961 ggtggtgatt tttggctgac tcagggaaca caagatcctg ttcattttgc ttttttagca
    28021 gaaaataagg aagaagttca ggcttgttat gaggctggca tagaggcagg tgggcgagac
    28081 aatggggttc ctggttatcg aagtgagcat ccgatttact atgctgcttt tatgattgac
    28141 ctggatggga acaatataga ggtggtttgc cataaagaat aaaaaagaaa aggaaaaata
    28201 atgacaaaac gtgtaacgat tattgacgta aaagactatg ttggtcagga agtgacgatt
    28261 ggcgcttggg ttgccaacaa atcaggaaaa ggaaaaatcg ctttcttaca attgcgtgat
    28321 ggaacagcct tctttcaagg tgtggctttt aaaccaaact ttgtcgaaaa atttggtgaa
    28381 gaagtgggac ttgagaagtt tgatgttatc aaacgcttga gccaagaaac gtctgtttat
    28441 gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg gctatgagtt ggacatcaca
    28501 gacatcgaag tgatcggtga atctcaagac tacccaatca caccaaaaga acacggaaca
    28561 gactttttga tggataaccg tcacttgtgg ctacgctctc gtaagcaagt agctgtgttg
    28621 caaatccgta acgctattat ctatgcaact tatgagttct ttgacaagaa cggttttatg
    28681 aagtttgaca gcccaattct ttcaggaaat gcggcagaag attctacaga actctttgaa
    28741 actgactact tcggaacgcc agcctacttg agccaatcag gtcagcttta cctagaagca
    28801 ggggctatgg ctcttggtcg tgtctttgac tttggtccag ttttccgtgc tgaaaaatca
    28861 aaaacacgcc gtcacttgac tgagttctgg atgatggatg ctgagtactc atacttgaca
    28921 catgatgagt cgcttgactt gcaagaagct tatgtgaaag ctcttctaca aggtgttctt
    28981 gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata cagaactctt gaaacgctac
    29041 attgcagagc cattcaaacg tatcacttac gatcaagcca ttgacctctt gcaagagcat
    29101 gaaaatgatg aagatgctga ctacgagcat cttgagcatg gtgatgactt tgggtcacca
    29161 cacgaaactt ggatttcaaa ccactttggt gtgccaacat ttgtcatgaa ctatccagca
    29221 gccatcaagg ccttctacat gaaaccagtt cctggaaatc cagagcgcgt gctttgtgca
    29281 gacttgcttg ctccagaagg ctatggagaa attatcggtg ggtctatgcg tgaggaagat
    29341 tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg atcgtacaga atatgaattc
    29401 taccttgacc ttcgtaaata cggtacagtt ccacacggag gatttggtat cggtatcgaa
    29461 cgtatggtaa ccttcgcagc aggaataaaa catatccgtg aagctattcc attcccacgt
    29521 atgttgcacc gtatcaaacc ataagaacag gaaaacgccc atgtggcgtt ttttcgaatt
    29581 ctagtgtttt tacttgcgta aaaaaatttt ttctagtata atagtttatt gtgagcgaac
    29641 ctcacttacc ccttgcaaag tcttggggtc attagaccaa aaggaggaac atatcaatgg
    29701 ctaaatacga aattctttat atcattcgtc caaacattga agaagaagct aaaaacgctt
    29761 tggtagcacg ttttgactct attttgactg acaacggtgc aactgttgtt gaatcaaaaa
    29821 cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt ccgtgaagga ctttaccaca
    29881 tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga gtttgaccgt ctttccaaaa
    29941 tcaacgctga cattcttcgt cacatgatcg tcaaaattga cgcgtaagaa ggtaaactat
    30001 gattaacaat gttgtacttg tagggcgtat gacacgtgac gctgagttgc gttatacccc
    30061 atcaaatgta gcagttgcga cttttactct tgcagtaaac cgtacattta agagtcaaaa
    30121 tggtgaacgt gaggctgatt ttattaatgt cgttatgtgg cgccaacagg ctgaaaatct
    30181 tgctaactgg gctaaaaaag gctcacttat cggggtgaca ggtcgtatcc agactcgtag
    30241 ttacgataac cagcaaggac aacgtgtcta cgtgacagag gtcgtggctg agaatttcca
    30301 aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt ggagcttact ctgcaccaac
    30361 tgcaaactat tcagcaccta caaattcagt accagacttt tcacgtaatg aaaatccatt
    30421 tggagcaaca aacccattgg atatttcaga tgatgattta ccattctaat ggacaactaa
    30481 acttataaag gagaaaaaac atggctcaac aacgtcgtgg cggattcaaa cgccgtaaaa
    30541 aagttgatta catcgcagca aacaaaattg aatatgttga ttacaaagat actgagcttc
    30601 ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg tcgtgtaaca ggaacttcag
    30661 ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc tcgcgtaatg gctttgatgc
    30721 ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc tctttttcat gagcttgaaa
    30781 acaagaaagc gaattaagac cccaacgggt cttttttcac aagctttgaa atgagagagc
    30841 gagttaggct cagtggctcc ctttttacga gtttgaaaac aagagaacac attaaaagca
    30901 cgatggagct ttttcataaa tatgtctctt ttctcatcca agaaattaaa ataaaaatga
    30961 taaacttttt gaaaataggg gatttgccta ctttatgata taatggaaag agttagattg
    31021 aaagaggtag tgagatggac gcgaaattaa gatacaaggc aaagaagatc aagattgtct
    31081 tttttgatat tgatgataca ttgcggaatt caaagacagg gtttattcca actacaattc
    31141 ccactgtttt taaacagttg cgtgaaaaag gaattttaac aggaatcgcc tctggacgtg
    31201 gcatttttgg tgttgttcca gagattcgtg atctcaagcc tgactttttt gtaactttga
    31261 atggggctta tatcgaagat aaaaaaggtc aggtcattta tcagcatcag attgaaaagt
    31321 cagatgttga ggagtatatc tcttgggcta agcaagaagg aattgagtat ggcttggttg
    31381 ggagtcatga tgccaagttg tcgactcgca ccgatatgat gagtgaagct atcaatccaa
    31441 tttatcccga cttagatgta gatcccgatt tccatgaaaa agaagatatc tatcagatgt
    31501 ggacttttga agataaggga gatgacttgc acttgcctga cagtctctca gacaaacttc
    31561 gcatggttcg ttggcatcaa cattcctctg atattgtgcc gatttcaggc tccaaagcga
    31621 cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc agagaaggtc atggtttttg
    31681 gagatggtct caacgacttg gaactctttg attatgctgg aatcagcgtt gccatgggaa
    31741 tttctcatga taaaatcaaa gaaaaagcag attatattac aaaaacatta gaagaagatg
    31801 gcatttttga tgccttagaa gtatttggta tggtagaaaa agaattgcat tttccacaag
    31861 tagacattga aacagtagaa ggtcctcttg cgactattaa gaccaatcac ggagacttac
    31921 gtatcaagct tttccctgaa catgctccta aaacagtggc taactttgta tctctttcaa
    31981 aagatggcta ctatgatggt gtcattttcc accgtattat caaggacttt atgatccaag
    32041 gtggagaccc aactggaact ggtatgggtg gcgagtcaat ctacggcgaa tcttttgagg
    32101 atgaattctc agaagagctt tacaatatcc gtggtgctct ttccatggca aatgctggtc
    32161 caaataccaa cggcagccag ttctttatcg tgcaaaacca acacctacct tattctaaga
    32221 aagaaattac tcgtggtggt tggccagaac cgattgcaga aatctatgcc aatcaaggtg
    32281 ggacacctca cctagaccgc cgtcacacgg tttttggtca gttagctgat gaagcatctt
    32341 acgctgtctt ggatgccatt gctgctgttg agacaggagc tatggacaag ccagttgaag
    32401 atgttgtaat tgaaactatt gaaatcgagg actaagatga aaatcggtga taagctaaag
    32461 gggcgtatta cagggattca gccctacggt gcctttgttg agttagagac gggtgatacg
    32521 gggctgattc acatttcaga aattcggaca ggatttattg aaaatattca tgaaaccttg
    32581 aaagtcgatg aagaggttca agttcaggta gtggatttag atgaatttac ggggaaagcc
    32641 agtctttcta tccgcacttt ggaggaagaa aagtaccagt ttcctagacg gagacgcttt
    32701 tcaagcgacc gctttaacta cggttttgct ccctttcgac gaatgctacc aatctggact
    32761 ggagaagccc tgcactattt aaaaaagaag aagtagttta gagttttata ttttttgtaa
    32821 tgttaatata aatttgctat aataggacca tggaagaaga acaattatta aaatcaggag
    32881 agcgcattaa ccagctcttt tcgacagata tcaaaatcat tcaaaataga gaggttttta
    32941 gctattcggt ggatagtgtt ctcttatcac gatttccacg ttttcctaag aaggggttga
    33001 ttgtagattt ctgtgctggg aatggagcag tggggctttt tgctagcact cgtactcaag
    33061 cacagatatt gtctgttgag attcaggagc gtttggcgga tatggctgaa cgctctgtcc
    33121 gtttgaatgg attagaggag caaatgcagg tcatctgcga tgatttgaaa aatatgcctg
    33181 ctcacattca ggggagtaag gtggatatga ttttgtgtaa tccaccctat ttcaaggtgg
    33241 atcctcattc taatctgaac gagagtgaac attatctctt ggctcgacac gaaatcacga
    33301 ctaatttgga agaaatctgt catagtgccc agagtattct caagtctaat gggcgtttgg
    33361 ccatggttca tcgtcctgat cgacttctgg atattttgga tacgttaaaa cgacataatc
    33421 tagcccctaa gcgcctgcag tttgtttatc caaaaagaga aaaggaagcc aatatgcttt
    33481 tgattgaggc gatcaaggat ggctcaacaa gtggctttaa ggtcttacct cctttgattg
    33541 tccacaatga tgatggctct tatacgcccg aaatcgaaga gatttattat ggatcataag
    33601 gcttatatgt acgttctgga gtgtcgtgat ggatcctact atataggcta tacgactgat
    33661 gtgagaagac gcctcgctat ccacaatagt gggaagggag ccaaatatac acgagcacgc
    33721 ttgccagtca aacttatcta tgctcaaggt tttgccagta aggaagaagc catgtcggct
    33781 gaagctcttc tcaagcgtaa gaagaggcca cagaaggaag aatttttatc tgaaaatcaa
    33841 gatagaaatt tactcagtta ttttgaagaa tcgtggggag tcctttgact cctcttacct
    33901 ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa acaaaatgag gtattatcat
    33961 gtccaagatt ctagtatttg gtcaccaaaa tccagactca gatgccatcg gatcatctgt
    34021 agcttttgcc taccttgcaa aagaagctta cggtttggat acggaagctg ttgcccttgg
    34081 aactccaaat gaagaaacag cctttgtctt gaactatttt ggtgtggaag caccacgtgt
    34141 tatcacttct gccaaagcag agggggcaga gcaagttatc ttgactgacc acaatgaatt
    34201 ccaacaatct gtatcagata tcgctgaagt agaagtttac ggtgttgtag accaccaccg
    34261 tgtggctaac tttgaaactg caagcccact ttacatgcgt ttggagccag ttggatcagc
    34321 gtcttcaatc gtttaccgta tgttcaaaga acatggtgta gctgtgccta aagagattgc
    34381 aggtttgatg ctttcaggtt tgatttcaga tacccttctt ttgaaatcac caacaacaca
    34441 cccaacagat aaaatcattg ctcctgaatt ggctgaattg gctggtgtga acttggaaga
    34501 atatggtttg gcaatgttga aagctggtac caacttggct agcaaatctg ctgaagaatt
    34561 gattgacatc gatgctaaga cttttgaact caacggaaat aatgtccgtg ttgcccaagt
    34621 gaacacagtt gacatcgctg aagttttgga acgccaagca gaaattgaag ctgcaatgca
    34681 agctgccaac gaatcaaacg gctactctga ctttgtcttg atgattacag atatcgtcaa
    34741 ctcaaactca gaaatcttgg ctcttggtgc caatatgtac aaggtcgaag cggctttcaa
    34801 cttcaaactt gaaaacaatc atgccttcct tgctggtgcc gtttcacgta agaaacaagt
    34861 ggtacctcaa ttgactgaaa gctttaatgc gtaagatttt gggtgtcagc tcaaaatcgg
    34921 aaagtctagt ttgccttata tcgaaaggag tttcggctcc ttttttctag gagtgaagta
    34981 tgttagaaaa tggcgatttg atttttgtga gagatgggtc agacatggga caggccatcc
    35041 agacttccac aggtaactat agccatgttg ccatttattt ggatgggatg atttatcatg
    35101 ctagtggaca ggctggtgtt gtctgtcaag aaccggcaga cttctttgag tccaatcatt
    35161 tatacgacct ctatgtttac ccagaaatgg atatccagtc ggtgaaggaa agagcttgca
    35221 aacatcttgg agcaccctac aatgcttctt tctatccaga tgcagctggt ttctactgct
    35281 cccagtatat agcagaaatc ctacctattt ttgaaactat tcctatgaaa tttggagatg
    35341 gggagcagga gattagtgat ttttggaggg agtattacat agaactaggt ctgcctgttc
    35401 ctctgaacca agctggtacc aatcctagtc agttggcagc atcgcctctg ttacaatgta
    35461 aagaaaggaa tcttcatgat tcagattttt aatccatctc gtttgacgag acagccattt
    35521 ttggagaatt gatccgctat ctggaccagt atgaggatgt gattctacgg gaaattaagg
    35581 ctcaatttcc agatgttgca gttgataaac tcatggaaga gtatataaag gcaggcttga
    35641 ttctacgtga aaataagcgc tattacctca attttcctac gcttgaatca cttgatagtc
    35701 ttgaactgga tcaagagatt tttgtcagag aagctagtcc ggtctatcaa gccttgttgg
    35761 agcagagttt tgagacggaa ttgcgcaatc aaatcaatgc agctatttta gttgaaaaga
    35821 cggactttgc gcgcattaaa atgaccctgt ccaattattt ttacaaggtc aaacagcagt
    35881 atcctttgac agaaaaacag caggagctct atgacatttt aggagatgtt aatcctgagt
    35941 atgccctcaa gtatatgacg gcttttttgt tgaaatttct caaaaaagac cagcttatgc
    36001 agaaatgccg tgatatcttt gtggacagtt tggttgtctt aggctatatt gtgcaaaatg
    36061 aagatggaaa gtatgagttg gctatcgatt ttgataagga gagattaact ttctacttag
    36121 cgtgatttct tgtttctgag tacattgttt gactttcctt agtattcggt ataaactata
    36181 tgtaaccggt aacacatatc ggaataaact aaaggagaca atcatatgtc acttgaaaac
    36241 aaattggaac aagcaacagg cgctgtcaaa gaaggttttg gtaaagttac tggagacagc
    36301 aagacagaac ttgaaggagc tgttgaaaaa acagttgcta aggcaaaaga cgttgtagaa
    36361 gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga aaaacgtttt tactaaataa
    36421 taggaaaaaa tcaagggttt cattttccct tgattttttc tattcttata aataattttc
    36481 tgcgacggct gtatctcctg ggtaggattc tttcttgccc tggatgattt ggtaacaatc
    36541 ggctccctta cccgcaataa taactgcatc taattcgtga tttgtgatag ccattgccgc
    36601 cttgatggct tcttggcgat ccgcaatctt ctcaacagga tgattgatgt agctactaat
    36661 ttcatctgca atggccattg ggtcttcata gttagggtca tcagcagtca gaaagacttg
    36721 aatctcaggg tgttgattga ggaggaggcc aaagtcctta cgacgacttt ctcccttgtt
    36781 tcctgttgat cccagaacca gagcaatctt tccggtttga tgagtttcaa ccacattgat
    36841 gagttttttc agactatccc cattgtgggc atagtcgatg aagaccttgg ctccattttt
    36901 ctgagtgagg acttccatac gaccaggaac gcgggttgca gcgatgcctt ttttgatgtc
    36961 ctcaagactt gctccgagac ggagacaagc aagtccagca gcaactgcat tttcttggtt
    37021 gaagttgcca atgagttgga tatcataatc tccagtgagt ttacccgtag ctgaaaagct
    37081 aaaggctttg gaattctcga tttggttatc aaattggcta ccatagaaat catggtcttg
    37141 atcttcaacc tgttctttca agactgagaa gtggtccatg tcactgttaa tgatgactgc
    37201 tcggctattt tccatcaaga gacgcttgtg gtagaaatag tcttcaaagc tagggtgttc
    37261 aatcgggccg atatggtctg ggctgatatt gaggaaaact cccacatcaa aggttagacc
    37321 atagacacgt ttgaccagat aggattgact ggagacttcc atgatgaggt gggtacggtc
    37381 attttgcaca gcctgattca tcatgtcaaa gaggtcaata ctctcagggg ttgtcaacgc
    37441 tgacttaaag aaagtctcgc catcaagagt tgtgttcatg gtcgacaaca tagcaggtct
    37501 atgcccttga gataagatgt tataggcgaa ataggttgct gttgtcttac ccttagtacc
    37561 agtaaaggca aggagtttga gtttctcttg tggattacca tagaactcca tggcaatcaa
    37621 actcatggct ttctttatat cgttcacaat gatgacaggg atatcgactt cgtagtcctt
    37681 ttcagctaca taccaagcta aaccttgtgt tatagcagaa agaaggtatt cttttttaaa
    37741 ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact tttcggctgt cgtagctgat
    37801 gctatcaaaa acaactttgc tgtagttgta gtggtaatga ccttggtcaa taatttcgcg
    37861 aaaaaggcca tctttcttta aaatatctaa tacggtttca atcttaatca tactttctat
    37921 tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa gtttataatg gaagataagg
    37981 agtttttcct agttatcaaa attgaatgag gaatctatgt cgcacgaaaa caatcaccag
    38041 caggcccaga tgttacgggg gactgcttgg ctaacggcta gtaactttat cagtcgccta
    38101 ctcggggctg tttacattat cccttggtac atctggatgg gggcttatgc agctaaggca
    38161 aatggtctct ttaccatggg ttacaatatc tatgcttggt tcttgttggt ttcaacagcg
    38221 gggattccag ttgcggtggc caagcaagtt gccaagtata ataccatgcg agaagaagag
    38281 catagctttg ccctgattcg gagcttctta ggctttatga caggactagg cctggttttt
    38341 gctttagtct tgtatgtctt tgctccttgg ctagcagact tgtctggcgt gggcaaagac
    38401 ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga ttttcccgtc tatgagtgtt
    38461 atccgaggat ttttccaagg gatgaataac ctcaaacctt atgccatgag ccaaattgct
    38521 gagcaggtca ttcgtgttat ctggatgctc ctagcaacct ttatcattat gaagctcggt
    38581 tcaggagatt atctagcagc cgttacccaa tcaacctttg ctgcctttgt cggtatggta
    38641 gccagttttg cagtcttgat ttatttcctt gcccaagaag gttcactcaa aagagtcttt
    38701 gaaacaggag ataagattaa cagtaagcgt ctcttggttg ataccattaa ggaagccatt
    38761 ccttttatcc tgacagggtc tgccatccag ctcttccaga ttttggatca gctgaccttt
    38821 atcaatagta tgagctggtt taccaactac agcaatgagg acttggttgt catgttttct
    38881 tatttctcag ccaatcctaa taaaatcacg atgattttga tttctgtagg ggtttcgatt
    38941 gggagtgttg gtttgccact tttgacggaa aactatgtca agggggactt gaaagcagct
    39001 tctcgtctgg ttcaggacag tctcacccta ctctttatgt tcttgctacc agcaacggtt
    39061 ggagtggtta tggtaggaga acctctatat acagtcttct atggtaagcc agatagtttg
    39121 gctctgggct tatttgtctt tgcagttttg cagtctatta ttttaggttt gtacatggtc
    39181 ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg ccgttctcta ttttatctat
    39241 ggttctattg ccaagctagt cttgcaacta cctaccatcg ccctcttcca cagttatggt
    39301 cctttgattt caacaaccat tgctctcatc attcctaacg tcttgatgta tcgggatatt
    39361 tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc gaaccatttt aatcagtttg
    39421 ctgaccctag tcatgtttct gttaatagga accatccagt ggctgttagg atttttcttc
    39481 caaccaagtg gacgtttgtg gagcttcttt tatgtagttc ttgtcggtgc catggggggt
    39541 ggactttata tggttatgag tctgcgtacc tatttattag ataaggtaat aggaaaagcc
    39601 caagcagatc gcctgcgagc aaaatttaag ctttcgtaag gtagcattta taaataaaag
    39661 gaataagttg aacaatcttt taggagaact tgaaacttat tcctttttta gcgtcaaaat
    39721 agctaaaatt atctttcaaa aatagaaaat gaggtttttt tgattttttg gaaaaaacaa
    39781 ttgactaaac aaaccaagag ttgtataata aaacaaatat ttaaagcagg aggttctgga
    39841 aatgaaaaag tctaagagca aatatctaac cttggcaggt cttgtcctgg gtacaggagt
    39901 tttattgagc gcgtgtggaa attctagcac tgcatcaaaa acctataact atgtttattc
    39961 aagtgatcca tctagtttga actatctagc agaaaaccgc gcagcaacat ccgatattgt
    40021 tgcaaatttg gtagacgggt tattagaaaa tgaccaatat gggaatatta ttccatcatt
    40081 agcagaggat tggactgttt ctcaggacgg tttgacctat acctacaaac ttcgtaagga
    40141 tgccaagtgg tttacttctg agggagaaga atatgcgcct gtaactgccc aggattttgt
    40201 gacaggtttg caatatgcag ctgataaaaa atcagaagct ttgtatctag tgcaggactc
    40261 tgttgctggt ttggatgact atatcactgg taaaacaagc gacttttcaa ctgtcggtgt
    40321 caaggcactt gatgaccaaa cggttcaata tactttggtt aaaccagaac tttactggaa
    40381 ttcaaaaaca cttgcaacga tactttttcc tgttaatgca gatttcctga aatcaaaagg
    40441 ggatgatttt gggaaggcgg atccatctag tattttgtac aatggacctt tcttgatgaa
    40501 agcacttgtc tcaaaatctg ctattgaata taagaaaaac cctaattact gggatgctaa
    40561 gaatgtcttt gtagacgatg tgaaattgac ctactatgat ggtagcgacc aagaatcact
    40621 ggaacgtaat tttacagctg gtgcttatac tacggctcgt ctttttccta acagctccag
    40681 ctatgaaggg attaaagaaa aatacaaaaa caatatcatc tatagtatgc aaaattcaac
    40741 ttcatatttc tttaatttta acctagatag gaagtcttac aattatactt ctaaaacaag
    40801 tgacattgaa aagaaatcga ctcaggaagc agttctcaat aaaaacttcc gtcaggctat
    40861 caattttgct tttgacagaa catcttatgg ggctcagtct gaagggaaag aaggtgcaac
    40921 aaagattttg cgtaacctag tggttcctcc aaactttgtc aatatcaagg gaaaagactt
    40981 tggtgaagtt gtagcctcta agatggtcaa ctatggtaag gaatggcaag gtatcaactt
    41041 tgcggatggt caagaccctt actacaatcc tgagaaagcc aaggctaagt ttgcggaagc
    41101 taagaaagaa ctcgaagcaa agggtgttca attcccaatc cacttggata agactgtgga
    41161 agtaacagat aaagtaggca tacaaggagt tagttctatc aaacaatcaa ttgaatctgt
    41221 tttaggttct gataatgtag tgattgacat tcagcaatta acatcagatg agtttgacag
    41281 ttcaggctac tttgctcaaa cagctgctca gaaagattat gatttatatc atggcggttg
    41341 gggacctgat tatcaagacc cgtcaaccta tctcgatatt tttaatacta atagtggagg
    41401 atttctgcaa aatcttggac tagagcctgg tgaggccaat gacaaggcta aggcagttgg
    41461 actggatgtc tatactcaaa tgttggaaga agctaataaa gagcaagatc cagccaaacg
    41521 ttatgagaaa tatgctgata ttcaagcttg gttgattgat agttctttag ttcttccaag
    41581 tgtttcgcgt gggggaacac catcattgag aagaaccgta ccatttgctg ctgcctatgg
    41641 tttaaccggt acaaaagggg ttgaatcata taaatacctc aaagtacaag ataagattgt
    41701 cacaacagac gaatatgcaa aagccagaga aaaatggttg aaagaaaaag aagaatccaa
    41761 taaaaaagtc caagaagaat tggcaaaaca tgtcaaataa aatctaattg tagataagtt
    41821 tgtgtaagaa gtctttgtgc ttaaaaacgc ataatatcag gtatataaaa tcctagatgt
    41881 tatgcgtttt gttataggaa gatttattag attttatcct caaattgagt tattcccgac
    41941 tttatccgtt gaaatattat aaggagtatt tatgaaatta aaattattaa gagtagatac
    42001 taaggtgatt atggggagtt tcttacttgt tctgtctagt ctacttgctt tgttgcttcc
    42061 ccttatctta aagggtttaa tagatgggag ttctattgaa aatataggtt ccaaagtatt
    42121 tcaatcgttt ttgattttta ttggtcaagc cttgttttct tctattggtt actatctgtt
    42181 tagtcaatcg ggtgaaaaaa agatagcaaa aatcaggaaa aaagtgatag aggggttgat
    42241 ttatgcagag aaatccttct ttgataagag ccaaagtggg gagttgactt ctgccattgt
    42301 caatgacacg agtgtcattc gtgagttttt aattacgact ttcccaaata ttattctgag
    42361 tttagttatg gtacttggtt ccattgtagt cttatttagt cttgattgga atctttctct
    42421 acttttattc atcactcttc cttgtatgat gtttattatc ttgccccttt ccaatatcag
    42481 tgaaaagtat agtcgtcgtt tacaggagga aatcggattt ttaacagggc aattgactga
    42541 aaagattcaa gaacatgaat taattaagac taaccaagca gagaaaagtg tacaggatgt
    42601 tttggataat tgtattgaaa gggtacaaaa caattcactg aaatcagata gggttacttc
    42661 ttttgagacc ccgtttgctc tcttatttat ctttgcgact atagctgtga tgctaaccta
    42721 tgggggttat cgggtcagcg caggatatat atctgtggga accttggttt cgtttttgat
    42781 ttacctcttt caattactta atcctattag taatatagct aattttgtaa ctgtttattc
    42841 taggagcaag ggatcttcag ttgcactgga gaacttgctt gcagttccta aagaaaaatt
    42901 tgagtgagga aaatcggtat caggacaagg gttgaatttt aaccatgtct attttggtta
    42961 tgatgaaaat cgacctatct taaaggatat tacttgttca attttcaagg ggcaaaaaat
    43021 tgcttttgtt ggaccatctg gatcaggaaa atcaacgatt gtgcgtttgt tagagcagtt
    43081 ttataaaccg cttgcaggag atattctaat ggagcaatca agtatatatg attttaactt
    43141 aaaagaatgg agaagtaaaa tcgcttgggt ttcacaaaat aatgcagtct tatctggcag
    43201 tattcgtgac aatctttgtc tcggtttgaa tcgcttagta actgatgatg aattgatgaa
    43261 agtgctagac ttagtatcac taggtgatga gattcgctcc atgaaagagg gactagatac
    43321 tgaagttggt gaacgcggac gattcttgtc aggggggcaa agccaaagac ttcaaatagc
    43381 tagaacctac ttaaaagatg ctgaaattct tatatttgat gaattcactg ctaatcttga
    43441 tgcggattct gagtatgcga ttatcagtat cctctattct gcattaaagg agaagacggt
    43501 tgtgattata gcgcatcgtt tgtcaacggt aaaagatgtg gattgtattt tcttcttaga
    43561 ggaggggaaa atcactggct caggaactca taaggaacta ctggaaaatc atgagcgtta
    43621 tgctcgtttt gtgcaggagc aaatgataga gtgaaggtgt cttttgagat tcaccatttt
    43681 atagtctatt aaagggagca ggaaaaactc cctttttata tagtttgaaa ctataactag
    43741 ctcttgaaaa caagaaaacg aaggatacaa aataagtggt acaatagtta ctatagattt
    43801 ggaggaattg tatgagcaag gaattacaca ttaacacaat tttagcacaa gcagggatca
    43861 agtctgatga ggcaacaggt gctttggtga caccacttca tttttcaacg acctatcagc
    43921 atccagagtt tggtcgatct actgggtttg actatacgcg cactaaaaat ccaactcgta
    43981 gtaaggctga ggaagtcttg gcggctattg agtcagcaga ctatgcccta gcgactagct
    44041 cagggatgtc agctattgta ctggccttta gcgtctttcc agtaggaagt aaggtcttgg
    44101 cagtgcgtga tctttacggt ggttcttttc gctggtttaa ccaagtggag caggaaggtc
    44161 atttccattt tacctatgcc aatacagaag aagagttgat tgccgagtta gaaaaggatg
    44221 tggatgttct ctatatcgaa accccaacca atcccttgat gttggaattt gatatcgaaa
    44281 aactagcaaa attggctcat gctaagggtg ccaaagtggt ggtggacaat accttctata
    44341 gccctatcta ccaacgtccg attgaagatg gagcagatat cgttctccat tcagcaacca
    44401 agtatctagc aggccacaat gatgtcttgg ctggagtggt tgtgaccaat agtttagaac
    44461 tatacgagaa gcttttttac aatcttaata caacaggggc agtcttgtct ccatttgaca
    44521 gctaccagtt gcttcgtggt ctcaagacct tgtctcttcg tatggagcgc tcaacagcta
    44581 acgcccaaga agtggttgcc tttttgaagg attctccagc agttaaggaa gttctctaca
    44641 ctggtcgtgg aggcatgatt tcctttaaag tagccgatga aacacgcatt cctcatattt
    44701 tgaacagtct caaggtcttc tcttttgcgg aaagtttggg tggagtggaa agtcttatta
    44761 cttatccaac gactcaaact catgctgata ttccagcaga ggtacgccat tcttatggtt
    44821 tgacagatga cctcttgcgt ttgtctattg ggattgagga tgctagagat ttgattgcag
    44881 atttgcgcca agccatagaa ggataagaca aagatgggaa aatatgattt tacaagcctg
    44941 cccaaccgtt tagggcacca tacctataaa tggaaagaaa cagaaacgga tagtgaagtt
    45001 ctaccagctt ggatagcgga tatggacttt gtggtcttgc ctgaaatccg ccaagccgtg
    45061 caaacttacg cagaccaact ggtttatggt tatacctatg ccagtgaaga cttaattaag
    45121 gaagttcaaa agtgggaagc tacacaatac ggttacaact ttgacaaaga ggctcttgtc
    45181 tttatcgagg gtgtggtacc agccatctca acagctattc aaacctttac aaaagaaggc
    45241 gaggcggttt taattaacac gcctgtctac ccaccctttg ctcgcagtgt caagttgaat
    45301 aatcgtagat tgattactaa ttccttagtg gaaaaggatg gtctgtttga gattgacttt
    45361 gaccaacttg aaaaggattt ggtggaagag gaggttaaac tctatattct ttgcaaccct
    45421 cacaatcctg gtggacgtgt ttgggaaaaa gaagtgttgg agaagattgg ccaactctgc
    45481 caaaaacacg gtgttttgtt agtttcggat gagattcacc aagatttgac cctctttggt
    45541 cacaaacacc agtctttcaa taccatcaat cctgccttca aaaattttgc tatcgtcttg
    45601 agcagtgcca ctaaaacatt taatattgct ggaacaaaaa attcctatgc agtcattgaa
    45661 aatcctaagt tgagactggc tttccagaaa cgcctgttgg ccaataatca gcatgaaatt
    45721 tcaggcttgg gttatttggc gacagaagct gcctatcgat acggtaaaga ttggctagag
    45781 gaactcaagc aagtctttga agaccacatc aattatgtga tggatctatt tggaaaagag
    45841 actaaaatca aggtcatgaa accgcaaggt acctacttga tttggcttga cttttcacct
    45901 tatgacctga ctgatgaaac attgcaagag ttgttgagaa atgaagccaa ggttatcctc
    45961 aaccgtggtt tggattttgg agaggaagga agtctccatg cccgcatcaa tatagctatg
    46021 cccaaatctc tgttgcaaga agtctgtcag cggattgtgg ctacttttgc caaacgttaa
    46081 aaatccagtc ttctaggaga aaagtcttcc tagaaggcta ttttcatagg cgaaaatatg
    46141 gtataataaa aagataaggt aaaggtgaaa atatggctaa attgattccg gggaaagttc
    46201 gtatcgaagg tgttgccctt tatgaaactg gtaaggttga tatcatcaag gaaaagaaca
    46261 atcggctcta cgctcgcgtt gcagaagaag aactgcgcta tagtttagag gatgatttgg
    46321 ttttttgtgc ctgtgattct tttcaaaaga ggggttactg tgtgcatttg gcagcgctag
    46381 agcattttct gaaaaatgat gagcgtggtc aggaaatctt gtggagtctg gaagaaggtc
    46441 atgaagaaaa agaggccgtt gaaaccaagg tgaccttggg tggcaagttt ttggatcgaa
    46501 ttttatctcc aaaatcagaa tgcgcctatg agttatcagc tgtgggtcag gtggaagcag
    46561 gaaccaatca tatcttgtgg actctgagaa tcggccaaat caatagccaa aaatactatg
    46621 tcattcggga tattccactt tttttaagga ttgtcgagca gagaaagtcg tatatgattg
    46681 gcaagattta tgaggagtct ctttcttggg aagcctttga tgacgccagc caagaacttt
    46741 tgactttctt gcacggacta acggaggaag ggctggttcc agacctcttt ttccaaaacc
    46801 aaggtcggca cctctttttc cctctgacct tttttgagca gggtgtgaat ttactgatgg
    46861 tcttgcccca ttttcaattt gaccatcaag tggatagcta ccaaactctg ctttttcagg
    46921 atatgcatgc tgatgccaat ctatttgcct ttacagtaac agaatactcg gactattttg
    46981 aaatggaaat cagtgagagt cctagggtca atgtctttta tcaaggagca gtacttttcc
    47041 ataaaggtca ggtttatttt ttaacagacc agcagatgcg tcttctcaag gaaattaaag
    47101 cgttacctgt gggtcaacaa ggaaagaaat acctgcaatt tgatagcagt gatcgagaca
    47161 aattggcctc ctgtctgact ctttttatcc agatgggcac cgtttcagct ccagaacgtc
    47221 tacaaatcaa aacttttgcg ccctcttttt actttgacag ggaagaagat aatcggattc
    47281 gtttagaaat tcagtttgat tatggaaata gacaggtatc tagccgacaa gagctagaag
    47341 aattaccatt ttcaagtgac gcggacttag aagaaagaat tttccaagtc tgtttggctg
    47401 cgggctttga agccgatttt caatcttggc gtcaggcctt aaaagcggag tctgtctatc
    47461 atttttttca tgatatcatt ccagtctttg aaaaactcgg gcatgttgac ctatcagata
    47521 aactagaaga gctttatagc ctagcgagtc ctcaggtgca gattgcctcc aagggaggtc
    47581 tcttggaaat ccagtttgat tttcaagata ttgcccagga ggaaattgac caagccatgc
    47641 aggccttggt tgccaatcag gatttttata ttgattcgtc taatcaagtt tactttttcg
    47701 atgaagaaac caagaaaatt cgccaaaatc tacaggaact ggggcaattt gaattaaaag
    47761 atgggacctt gcaggctcgg aaatccttgg cctacagttt agctcatctc tttgaagggc
    47821 gagaccgtgt ttctttttca caagaattcc agaatctggc ccaggatttg acgcatccag
    47881 aggactttcc tttgcaagca actcaggtca aggctgactt gcgagattat caggaaaagg
    47941 gaattggctg gttgcagatg ctccatcatt atggttttgg tgggattttg gctgatgata
    48001 tgggacttgg gaaaaccctt cagaccattg cttttttgac tagtcaagtg acaaaagaaa
    48061 gtcgggtttt gattctcgct ccgtcgggtt tgatttacaa ctgggcagat gagtttcaga
    48121 aatttgctcc acagttggat gtggctgttg ttcatggttt gaaagcaagt cgtgaggaga
    48181 ttcttgccga gagccatcaa atctatgtga ctagctatgc caccttccgt caggacagtg
    48241 agctttatca ggggatggcc tttgacttcc ttttcttaga tgaagctcag gtcatgaaaa
    48301 atgcccagac caagattgcc cagaccttga gacaatttgt ggtgccgtcg gtctttgcct
    48361 tgtcaggaac tccgattgaa aaccatctgg gtgagttgtg gtctattttc caaatcgtca
    48421 tgcccggact tttgccaagc aagaaagaat ttatgaaatt gccagcagag cgagtggctc
    48481 agtttatcaa gcctttcgtg atgcgacgca agaaagaaga agttctgact gaattgccag
    48541 acttgattga ggtggtttat aaaaatgaac tggaagacca gcaaaaggct atttaccttg
    48601 cccagttaca acagatgcga gaccatctgg ctcaagtgtc agaacaggaa tttcagcgaa
    48661 gtcgtgtgga aattttatct ggtttgatgc gcttgcgtca aatatgtgac actcctgccc
    48721 tgtttatgga agattatcag ggagccagcg gcaaactaga tagtctccga gacctactgg
    48781 tacaggtggc agacggcgga caccgtgtct tgattttctc tcagttcaag ggaatgttgg
    48841 aaaaaattga acaagaacta ccagacttgg gcctgacttc ctttaaaatt acgggttcaa
    48901 ccccatccaa ggaaagacaa gacatgacca aggcctttaa ccaaggagaa agagatgcct
    48961 ttctgatttc cctcaaggct ggtggggtcg gtctgaacct gacaggtgca gatacagtga
    49021 tcttggttga cctctggtgg aatcctgcgg tggaagcgca agccattggc cgtgcccatc
    49081 ggatgggtca ggaagaaacg gttgaggtct atcgcttggt gaccaaggga accattgaag
    49141 aaaaaattca ggaactccaa gaacaaaaga aacatctggt gtcacaagta ttggacggca
    49201 cagagtcacg tggtagtctg accctagcag aaattagaga aattttggga atttctgaag
    49261 ccagcacttg aaaaatcaag acaatacgct ataatgaagt gttgaaagga aatagaaaat
    49321 gaaacaagaa cgatttccat tggtgtcaga tgacgaggtc atgttgactg aaatgccagt
    49381 catgaatctc tatgatgagt ctgatctgat cagtaatatc aagggtgagt atcgagataa
    49441 aaattattta gaatgggctc ctattgctga agaaaaacca gtaaaaccga ttgaaaagca
    49501 agtcgagaaa cctaaaaagg ctcctttagg ggttaaaaaa gaaggaaaga gctatgcgga
    49561 ggtggcgcgt gaagaagcgc gtgcagactt gaaaaagaaa cgctctgcta actacctaac
    49621 tcaggatttc agtcttgcga gacgtcattc tcagcccagt ctagttagac agggcaatca
    49681 accgacagct cctttccaaa aggaaaatcc tggtgaattt gtcaaatata gccaaaaatt
    49741 gacccagtct cattatatct tggcggaaga agttcattct atccctacca agaatgaaga
    49801 agtgtcagca cctgctccaa agaaaaacaa ttatgatttt ctaaagaaga gccaaatcta
    49861 caataaaaaa agtaaacaaa cagaacaaga acgtcgggtt gcccaagagt tgaatctgac
    49921 cagaatgaca gaatagggga gaaaacatgt caaagacata tcattttatc ggaattaagg
    49981 gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag gttcagggat
    50041 cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga attaccattc
    50101 ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga aatgcctttc
    50161 gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc tacaaacgtt
    50221 accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta gcaggagcac
    50281 atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt acagatacca
    50341 gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat tttgtctttg
    50401 aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct attatcacca
    50461 acattgactt tgaccatcca gattatttca caagtctcga ggatgttttt aatgccttta
    50521 acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat gctgaattgc
    50581 gtaagattac gtctgatgca ccaatttatt attatggttt tgaagctgaa ggcaatgact
    50641 ttgtagctag tgatcttctt cgttcaataa ctggttcaac cttcaccgtt catttccgtg
    50701 gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc atgaatgcga
    50761 cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg cgtgagcact
    50821 tgaaaacatt tgccggtgtt aaacgtcgtt tcactgagaa aattgtcaat gatacagtga
    50881 ttatcgatga ctttgcccac catccaacag aaattattgc gaccttggat gcggctcgtc
    50941 agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt acaagaacca
    51001 ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt tatctagcgc
    51061 aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa gacctagcca
    51121 acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctcca ctcctagacc
    51181 atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat gaatactcat
    51241 ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc atggaaattc
    51301 caattaagat cattcaggca agcaagtctg atttgcctga gataggggca cttcagacct
    51361 cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt atccgtaagt
    51421 gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat attttatcaa
    51481 gtccccagtc agacaatccg caatgtctaa aagtacattc tttagtcatc gagtctgacc
    51541 atcagagaca gggcctggga acacttcttc ttgcagcctt gaaagaggtg gcagttgagc
    51601 tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat tttgaaatga
    51661 acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc tatagtatga
    51721 tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa gattagaaga
    51781 tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag ccattcctcc
    51841 ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg ctgaaaaaga
    51901 aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc tgcaagacca
    51961 gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata tctctgtgac
    52021 ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat tgctgacagc
    52081 cttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct gtcatgacta
    52141 tctcatcgcc tactatgaaa aacatggatt tgtcaacgaa ggccagtccc agtcaacctt
    52201 tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta ggaaaagtat
    52261 catagattgc tttttttgga cttttaagat ataatattat ggattatcaa caaggaggaa
    52321 aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga gcagattctg
    52381 agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga ggcagtagtt
    52441 cgcactcctg caaatgaacc ttcaactgaa gaactcatgg ctgattcctt gtcaacggta
    52501 gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg tgtaccagct
    52561 tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc aagtcaagat
    52621 gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtccaggtcc tgttagacct
    52681 aagaaacttg aaagagaata caatgaaacc ccaacaaggg tagctgtttc ctatacgacg
    52741 gcagagaaaa aagcagaaca agcaggtcca gaaacaccta cgcctgctac agaaacagtg
    52801 gatatcatca gagatacatc acgtcgtagc cgtagagaag gagcaaaacc cgttaagcct
    52861 aagaaagaga agaagtcaca tgtgaaagct tttgtgattt cattccttgt attccttgcc
    52921 ttgctctcag caggtggtta ctttggttac cagtacgtgc tagattcctt attacctatc
    52981 gatgctaatt ctaagaaata tgtgacggtt ggaattccag aaggttcaaa cgttcaagaa
    53041 atcggtacga cgcttgaaaa agctggtttg gtaaagcatg gtctgatttt tagtttttat
    53101 gccaagtata aaaattatac cgacttgaaa gcaggttact acaatttgca aaagagtatg
    53161 agtacagaag acttactcaa agagttgcaa aaaggtggaa cagatgaacc gcaagaacct
    53221 gtacttgcga ctttgacaat tccagaaggt tataccttgg atcagattgc tcaagctgtg
    53281 ggtcaattgc aaggtgactt caaagagtct ttgacagcgg aggctttctt ggctaaagtt
    53341 caagatgaga cgtttatcag tcaagcagta gcgaaatatc ctactttact ggaaagtttg
    53401 cctgtaaaag acagcggtgc gcgttatcgt ttggaaggat accttttccc agctacatac
    53461 tctatcaagg aaagcacaac tattgagagc ttgattgatg agatgttagc tgctatggat
    53521 aagaacctat ctccttacta tagtactatc aaatctaaaa acttgactgt caatgagttg
    53581 ttgaccattg cttccttggt cgaaaaagaa ggtgccaaga cagaagatcg taagctcatt
    53641 gcaggtgtat tctacaatcg tttgaatcgt gatatgccac ttcaaagtaa tattgcaatc
    53701 ttgtatgccc aaggaaaact ggggcaaaat atcagtctag ctgaggatgt tgcgattgat
    53761 accaacattg attcacctta taatgtttat aaaaatgtag gtctcatgcc tggtccagtc
    53821 gatagtccaa gtctggatgc gattgagtca agcatcaatc aaactaagag cgataacctc
    53881 tactttgtag cagatgtcac agaaggcaag gtctactatg ctaacaatca agaagaccac
    53941 gaccgcaatg tcgctgaaca tgtaaacagc aaattaaact aaacaaacta aaattatgtg
    54001 atacttcaca taattttctt tagaaaatat tatcagaaga aagttgagaa aaatggcaga
    54061 aaaaacatat cctatgaccc ttgaggaaaa ggaaaaactt gaaaaagaat tagaagaatt
    54121 gaaattggtt cgtcgaccag aagtggtaga acgcattaag attgcccgtt catacggtga
    54181 cctttcagaa aacagtgagt acgaagcagc taaggatgaa caagcctttg tcgaaggaca
    54241 aatctctagc ttagaaacaa aaatccgcta tgctgaaatc gtcaatagcg acgcagttgc
    54301 ccaggacgaa gtagcgattg gtaaaacagt caccatccaa gaaattggtg aggacgaaga
    54361 agaagtttat attatcgtag gttcagctgg tgcggatgcc tttgtaggta aggtttcaaa
    54421 tgaaagccca attgggcagg ccttgattgg caagaaaaca ggtgatacag caaccattga
    54481 aacgcctgtt ggtagctatg atgtaaaaat cttgaaggtt gaaaaaacag cctaaaaaca
    54541 gaaaaaggag tggggaggcg atgtgcttca ctcactcctt tttccatttt gctactcttc
    54601 gaaaatctct tcaaaccacg tcagcgtcgc cttgccgtat gtatggttac tgactttgtc
    54661 agtttcatct acaacctcaa aacagtgttt tgagctaact tcgtcagttt catctacaac
    54721 ctcaaaacta tgttttgagc tgacttcgtc agtttcatct acaacctcaa aaccatgttt
    54781 tgagccgact tcgtcagttt catctacaac ctcaaaacta tgttttgagc tgacttcgtc
    54841 agttctatct acaacctcaa aacagtgttt tgagcaacct gcggctagtt tcctagtttg
    54901 ctctttgatt tttattgagt attagatgta tagtgcattg aagttaaaat agtacacttt
    54961 gatttctaag acattgttag aaattagatt aaattcctta atcgatttgc gcatgtttta
    55021 tttcatttca ctatacttta gattggaaaa taaggaatca cataaatcgc aagaaatagg
    55081 gaatctgatt cgtgtttata accgttcaaa aagagaagag gctgaaagtg agccacttaa
    55141 tctttatgtc gaagatgaaa agggcaatct cctggcaggt ttgatagcag agacttttgg
    55201 aaattggcta gaaatcgagt atttgtttgt aaaagaggaa ctgcgagggc aaggaatcgg
    55261 ttcaaaacta ttacaacagg cagaaagtga agctaagaat cgaaattgtt gttttgcctt
    55321 tgtcaatact taccagttcc aggcaccgga cttttatcag aaacatggct acaaggaagt
    55381 tttttctttg caagactatc tctacattag gcaaagatat tattaccaaa agaatctgta
    55441 aggtgagtat ggaggtataa tacaaagaga ggctcgcaca taagtatgga ggtggactga
    55501 tgtatatgag taactatcga taaataccag ttataaccta gaaattgtgt ctttctagac
    55561 gatattgagg acaatataat cgtagcccca aaattaggaa tcaagactta tcaggttaag
    55621 aaaagaagtg atgttgttga tattttaaac aatttattta aactaaaaac tctctatcta
    55681 ttaatccgag attcccctct cggattttgt gttgctttca ttaaatttac aggtaagact
    55741 tgctagcttc agtaaatata cacaagtttt tcagaataga gtgaaatcca aaagaaaatg
    55801 gaaataatga aagctcttgt aggcataaga aaacacctct gtgttatact tgttgttcaa
    55861 ccacaaacac aagaaaggca caga
//
LOCUS       DAVHBD010000007        55179 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000007 DAVHBD010000000
VERSION     DAVHBD010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55179
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.007"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..163
                     /locus_tag="VVK04_000437"
     CDS             <1..163
                     /locus_tag="VVK04_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEU3989141.1"
                     /translation="HGNMYGVIKEVLKINEGLNIGSVRSPLTPVTEEDRPVVEAAAAL
                     IRETKERFL"
     gene            181..1065
                     /locus_tag="VVK04_000438"
     CDS             181..1065
                     /locus_tag="VVK04_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU3989142.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(1081..1932)
                     /locus_tag="VVK04_000439"
     CDS             complement(1081..1932)
                     /locus_tag="VVK04_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU3989143.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            2132..4189
                     /gene="pbp2b"
                     /locus_tag="VVK04_000440"
     CDS             2132..4189
                     /gene="pbp2b"
                     /locus_tag="VVK04_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU3989144.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLTDYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            4200..4796
                     /gene="recR"
                     /locus_tag="VVK04_000441"
     CDS             4200..4796
                     /gene="recR"
                     /locus_tag="VVK04_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU3989145.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            4972..6015
                     /locus_tag="VVK04_000442"
     CDS             4972..6015
                     /locus_tag="VVK04_000442"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU3989146.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNNITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPKLIERLVDL
                     AKESFDKREAHLI"
     gene            6099..7472
                     /locus_tag="VVK04_000443"
     CDS             6099..7472
                     /locus_tag="VVK04_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU3989147.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDTVIFYGQDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            7459..8070
                     /locus_tag="VVK04_000444"
     CDS             7459..8070
                     /locus_tag="VVK04_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU3989148.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            8161..8865
                     /locus_tag="VVK04_000445"
     CDS             8161..8865
                     /locus_tag="VVK04_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU3989149.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            9084..10457
                     /gene="ftsA"
                     /locus_tag="VVK04_000446"
     CDS             9084..10457
                     /gene="ftsA"
                     /locus_tag="VVK04_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU3989150.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            10474..11733
                     /gene="ftsZ"
                     /locus_tag="VVK04_000447"
     CDS             10474..11733
                     /gene="ftsZ"
                     /locus_tag="VVK04_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU3989151.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            11738..12409
                     /locus_tag="VVK04_000448"
     CDS             11738..12409
                     /locus_tag="VVK04_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU3989152.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            12419..12958
                     /locus_tag="VVK04_000449"
     CDS             12419..12958
                     /locus_tag="VVK04_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU3989153.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            12958..13221
                     /locus_tag="VVK04_000450"
     CDS             12958..13221
                     /locus_tag="VVK04_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU3989154.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            13218..14003
                     /locus_tag="VVK04_000451"
     CDS             13218..14003
                     /locus_tag="VVK04_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU3989155.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            14012..14800
                     /gene="divIVA"
                     /locus_tag="VVK04_000452"
     CDS             14012..14800
                     /gene="divIVA"
                     /locus_tag="VVK04_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU3989156.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            15148..17940
                     /locus_tag="VVK04_000453"
     CDS             15148..17940
                     /locus_tag="VVK04_000453"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU3989157.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELIYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIVEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            18343..18723
                     /locus_tag="VVK04_000454"
     CDS             18343..18723
                     /locus_tag="VVK04_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989158.1"
                     /translation="MKLKRLALISGIVGLVGGILLLIGPFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            19257..19949
                     /locus_tag="VVK04_000455"
     CDS             19257..19949
                     /locus_tag="VVK04_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU3989159.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            20002..22413
                     /locus_tag="VVK04_000456"
     CDS             20002..22413
                     /locus_tag="VVK04_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU3989160.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TDVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGNGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            22663..23364
                     /locus_tag="VVK04_000457"
     CDS             22663..23364
                     /locus_tag="VVK04_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989161.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            23366..26074
                     /locus_tag="VVK04_000458"
     CDS             23366..26074
                     /locus_tag="VVK04_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU3989162.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ANVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQIGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(26170..26661)
                     /gene="tpx"
                     /locus_tag="VVK04_000459"
     CDS             complement(26170..26661)
                     /gene="tpx"
                     /locus_tag="VVK04_000459"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU3989163.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(26784..27713)
                     /gene="psaA"
                     /locus_tag="VVK04_000460"
     CDS             complement(26784..27713)
                     /gene="psaA"
                     /locus_tag="VVK04_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU3989164.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(27745..28593)
                     /locus_tag="VVK04_000461"
     CDS             complement(27745..28593)
                     /locus_tag="VVK04_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU3989165.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(28590..29312)
                     /locus_tag="VVK04_000462"
     CDS             complement(28590..29312)
                     /locus_tag="VVK04_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU3989166.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKTKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            29603..31495
                     /gene="pepO"
                     /locus_tag="VVK04_000463"
     CDS             29603..31495
                     /gene="pepO"
                     /locus_tag="VVK04_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU3989167.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(31617..32246)
                     /locus_tag="VVK04_000464"
     CDS             complement(31617..32246)
                     /locus_tag="VVK04_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU3989168.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            33240..35462
                     /locus_tag="VVK04_000465"
     CDS             33240..35462
                     /locus_tag="VVK04_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU3989169.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            35492..35935
                     /locus_tag="VVK04_000466"
     CDS             35492..35935
                     /locus_tag="VVK04_000466"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU3989170.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(35974..36388)
                     /locus_tag="VVK04_000467"
                     /pseudo
     CDS             complement(35974..36388)
                     /locus_tag="VVK04_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36407..36820)
                     /locus_tag="VVK04_000468"
     CDS             complement(36407..36820)
                     /locus_tag="VVK04_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989171.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(36922..37599)
                     /locus_tag="VVK04_000469"
     CDS             complement(36922..37599)
                     /locus_tag="VVK04_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU3989172.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTLLFGAIDYILGNKAAIITYPVTFLIYTFAIKKWESSQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMDLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIE
                     GNSNKEY"
     gene            complement(37776..38426)
                     /locus_tag="VVK04_000470"
     CDS             complement(37776..38426)
                     /locus_tag="VVK04_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU3989173.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            38538..39380
                     /locus_tag="VVK04_000471"
     CDS             38538..39380
                     /locus_tag="VVK04_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU3989174.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            39456..39893
                     /locus_tag="VVK04_000472"
     CDS             39456..39893
                     /locus_tag="VVK04_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU3989175.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            39962..40264
                     /locus_tag="VVK04_000473"
     CDS             39962..40264
                     /locus_tag="VVK04_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989176.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSCFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(40355..41428)
                     /locus_tag="VVK04_000474"
     CDS             complement(40355..41428)
                     /locus_tag="VVK04_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU3989177.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVTTVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     EKETLGRLTQLLIDTRYQVWKNR"
     gene            41584..42261
                     /locus_tag="VVK04_000475"
     CDS             41584..42261
                     /locus_tag="VVK04_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3989178.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            42254..43228
                     /locus_tag="VVK04_000476"
     CDS             42254..43228
                     /locus_tag="VVK04_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU3989179.1"
                     /translation="MLDWKQFFLAYLRSRSRLFVYLLSLAFLVLLFQFLFASLGIYFL
                     YFFLLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(43277..45220)
                     /gene="thrS"
                     /locus_tag="VVK04_000477"
     CDS             complement(43277..45220)
                     /gene="thrS"
                     /locus_tag="VVK04_000477"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU3989180.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPHIEDEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(45380..45601)
                     /locus_tag="VVK04_000478"
     CDS             complement(45380..45601)
                     /locus_tag="VVK04_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU3989181.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIW"
     gene            46460..46951
                     /locus_tag="VVK04_000479"
     CDS             46460..46951
                     /locus_tag="VVK04_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HEU3989182.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVIGGAGS
                     LYIDETKMTRLLDTPDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGN"
     gene            47230..47499
                     /gene="rpsO"
                     /locus_tag="VVK04_000480"
     CDS             47230..47499
                     /gene="rpsO"
                     /locus_tag="VVK04_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU3989183.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            48313..48927
                     /locus_tag="VVK04_000481"
     CDS             48313..48927
                     /locus_tag="VVK04_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU3989184.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(49220..49969)
                     /locus_tag="VVK04_000482"
     CDS             complement(49220..49969)
                     /locus_tag="VVK04_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU3989185.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            50102..52438
                     /locus_tag="VVK04_000483"
     CDS             50102..52438
                     /locus_tag="VVK04_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU3989186.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAVKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            52539..53216
                     /locus_tag="VVK04_000484"
     CDS             52539..53216
                     /locus_tag="VVK04_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU3989187.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQVKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLDKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            53203..54000
                     /locus_tag="VVK04_000485"
     CDS             53203..54000
                     /locus_tag="VVK04_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU3989188.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            54017..55120
                     /locus_tag="VVK04_000486"
     CDS             54017..55120
                     /locus_tag="VVK04_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU3989189.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
BASE COUNT        16203 a        10293 c        12647 g        16036 t
ORIGIN      
        1 tcatggaaat atgtacggtg tcatcaaaga agtcttgaaa atcaatgaag gcttgaatat
       61 tggatctgtt cgttcaccat tgacaccagt gactgaagaa gatcgtccag ttgtagaagc
      121 ggctgctgcc ttgattcgtg aaaccaagga gcgcttcctc taatctaaaa ggaggtattt
      181 atgacatatt acgttgcaat tgatatcggt ggaaccaaca tcaagtatgg tttggttgat
      241 caagaggggc aacttcttga atcgcatgaa atgccaactg aggcgcataa gggtggacct
      301 catatcttac aaaagaccaa agatatcgta gctagttatt tagaaaaagg cccagtagca
      361 ggtgttgcca tatcttctgc tgggatggtg gatccggata agggtgagat tttctatgct
      421 gggccgcaaa tccctaacta cgcaggcacc cagttcaaaa aggaaatcga agaaagcttt
      481 actattcctt gtgagattga aaatgatgtc aactgtgcag gtcttgctga ggcagtatct
      541 ggttcaggca agggagcaag tgtgacactt tgcttgacca ttggaacagg tatcggtggt
      601 tgcttgatta tggataggaa agtcttccat ggttttagca attcagcctg tgaagtcggg
      661 tatatgcata tgcaggatgg agcttttcaa gacttggctt ctacaacagc tttagtgaaa
      721 tatgtagctg aagcccatgg agaagatgtt gatcagtgga atggccgtag aattttcaaa
      781 gaagccactg aaggaaacaa aatctgcatg gaaggtattg accgtatggt tgactatcta
      841 ggaaaaggtc tggcaaatat ttgctacgtt gccaatccag aagtggttat tcttggtggt
      901 ggtatcatgg ggcaagaggc tatcctcaaa cctaagatcc gcacagcctt gaaagaggct
      961 ttggtaccaa gtttagcaga aaaaacacga ttagaatttg cccatcacca aaatacagca
     1021 gggatgttgg gtgcatatta tcattttaag acaaaacaat cctagtttgg ctcagccaaa
     1081 ctaggatttt cttacacgtt tttgtctacg atagccgttg agttttttat tttcccagta
     1141 gctattaaag attttttcct tgctttcgcg attgatttcc aaaaagtagg cataaatcaa
     1201 atcgataaag aagagcatag gaagttgagc ggatattcgt tggatatagg agggttggct
     1261 gtgggtggct acaagaacag tctctgtata ggtctggcta tctttattgg gaacacttgt
     1321 aaagagtaca gtctttgccc ccatctcctt ggcatctaat agactatcta aaatagaagg
     1381 agttgagcct gaaagtgaga agcccagtac tagacaattt tcatccatga tgctggttgt
     1441 ccaggcaaag ccgtcttggt ctgtcaaagc ttcgcagacc acacctagtc gcataaaacg
     1501 taatttcatt tcacgggcga cgaggccaga actccctgtt ccaaagaagt agatacgctc
     1561 agcatcttcg attagctggg caattcgttc tagttggatt tcgtcaatca agtcttgtgt
     1621 ttgttccctc atattgctat aacttctgag gactcgtttg gtcagtggac tgtgcttgga
     1681 gacttggttg gcttgatttt ctgcctgatg ttggtattgg aaaataaatt ctcggtagcc
     1741 agtaaagcca cactttttag caaagcgggt caaagcagct tgagaaatat gtaatttttg
     1801 ggtgacttgt tgagaagata aatcatctgt aatcgtttca gcttgcaaaa aatagcgagc
     1861 gatttcttgc tctaggtctg tcatttcttc aaaatgtgaa tcaatgatag ttgcgatatc
     1921 tggtttgtcc atagggaaag ctcctttaca tgagtcatac tggaagacta gatcagggaa
     1981 tagtcacact tcattataac acataatata aggatagata aataaaaacg catctctgtt
     2041 ttaaaaacga aaaaatcgaa aaagcttctc tcttttccat aattttctac tcaaattgtg
     2101 gtacaattaa gagtaagatt ttaagttaga aatgagactg atttgtatga gaaaatttaa
     2161 cagccattcg attccgattc ggcttaattt attgttttca atcgtcattt tactctttat
     2221 gaccattatt ggtcgtttgt tgtatatgca ggttttgaac aaggattttt acgaaaaaaa
     2281 gctagcctca gctagtcaga ccaagattac aagcagttca gcccgtgggg aaatttatga
     2341 tgctagtgga aaacctttgg tagaaaatac gttaaagcag gttgtttcct ttacgcgtag
     2401 caataaaatg acggctacag acttaaaaga aacagctaaa aagttactga cttatgtgag
     2461 catcagttct ccaaatttga cagaacgcca gctgacggat tactatttgg ctgatcctga
     2521 aatctataaa aaaatagtgg aagctctccc aagtgagaaa cgcttggatt cagatggcaa
     2581 tcgtctatcc gaatcagaac tgtataacaa tgcggtcgat agtgtacaaa cgagtcaact
     2641 aaactataca gaggatgaaa agaaagaaat ctatcttttt agtcagttaa atgctgttgg
     2701 aaactttgcg acaggaacca ttgcgacaga tcctctaaat gattctcagg tggctgttat
     2761 tgcctctatt tcaaaggaga tgcctggcat tagtatttct acttcttggg atagaaaggt
     2821 tttggaaact tccctttctt ctatagttgg gagtgtatcc agtgaaaaag ctggtctccc
     2881 agcggaagaa gcagaagcct atcttaaaaa aggctattct ctaaatgatc gtgtaggaac
     2941 ctcctatttg gaaaagcaat atgaagagac cttacaagga aaacgctcgg taaaagaaat
     3001 ccatctggat aaatatggca atatggaaag cgtggataca attgaggaag gtagtaaggg
     3061 aaacaatatc aaactgacca ttgatttggc cttccaagat agcgtggatg ctttactgaa
     3121 aagttatttc aattccgagc tagaaaatgg tggagccaag tattctgaag gtgtctatgc
     3181 agtcgccctt aacccaaaaa caggtgcggt tttgtctatg tcagggatta aacatgactt
     3241 gaaaacggga gagttgacgc ctgattcctt gggaacggta accaatgtct ttgttccagg
     3301 ttcggttgtc aaggcggcga ccatcagctc aggttgggaa aatggagtct tgtcaggaaa
     3361 ccagaccttg acagaccagt ccattgtctt ccaaggttca gctcccatca attcttggta
     3421 tactcaggct tacggttcat tccctatcac agcggtccaa gctctggagt attcatcaaa
     3481 tacctatatg gtccaaacag ccttaggtct tatggggcaa acctatcaac ccaatatgtt
     3541 tgtcggcacc agcaatctag agtctgctat ggagaaactg cgttcaacct ttggcgaata
     3601 tggcttgggt actgcgacag gaattgacct accagatgaa tctactggat ttgttcccaa
     3661 agagtatagc tttgctaatt acattactaa tgcctttggg cagtttgata actatacgcc
     3721 gatgcagttg gctcagtatg tagcaactat tgcaaataat ggtgttcgtg tggctcctcg
     3781 tattgttgaa ggcatttatg gtaataatga taagggagga ctgggtgact tgattcagca
     3841 actgcaaccg acagagatga ataaggtcaa tatatccgac tccgatatga gcatcttgca
     3901 ccaaggtttt tatcaggttg cccatggtac tagtggattg acaactggac gtgccttttc
     3961 aaatggtgcc ttggtatcca ttagcggaaa aacaggtaca gccgaaagct atgtggcaga
     4021 tggtcagcaa gcaaccaata ccaatgcggt ggcctatgcc ccatctgata atccccaaat
     4081 cgctgtcgca gtggtctttc ctcataatac caatctaaca aatggtgtag gaccttccat
     4141 tgcgcgtgac attatcaatc tgtatcaaaa ataccatcca atgaactaga aaggaaatta
     4201 tgctttatcc aacacctatt gccaagttga ttgacagtta ttctaagtta ccaggtatcg
     4261 ggattaagac ggctacgcgt ctggcctttt atacgattgg gatgtctgct gatgatgtca
     4321 atgaatttgc aaaaaatctc ctttctgcta agagagaatt gacatattgt tctatttgtg
     4381 gacgtttgac agacgacgat ccttgttcta tctgtactga tccgactcgt gaccagacaa
     4441 caattttagt tcttgaggat agtagagatg tggcagccat ggaaaatatc caagaatacc
     4501 atggactcta tcatgtcctg catggcctca tttctcctat gaatggtatc agtccggacg
     4561 atatcaatct caagagcctt atgactcgtc ttatggatag tgaggtttca gaagtgattg
     4621 tggcgactaa tgctacagcg gatggtgaag cgacttccat gtatctttca cgtttgctca
     4681 agccggctgg tatcaaggtt acgcgtctag cacgaggtct cgctgtggga gcggacattg
     4741 agtatgcgga cgaagtgaca ctcttacgag cgattgaaaa tcggacagag ttgtaagtgt
     4801 aggcaaattt acgaactccc ttcatttata aaaaatcaaa gaggctgaaa atcgttccta
     4861 tcggcctctt tttgtatagt gtgatgagta ggatcgggtt caagttttaa aaaaccaagc
     4921 aaatatgata tactaaagag cgagtattct agtagaatta ggacaaataa tatgaaacaa
     4981 acgattattc ttttatatgg tggacggagt gcggaacgcg aagtctctgt cctttcagct
     5041 gagagtgtca tgcgtgcggt caattacgac cgtttcacag tcaagacttt ctttatcagt
     5101 cagtcaggtg actttatcaa aacacaggaa tttagtcatg ctccggggca agaagaccgt
     5161 ctcatgacca atgaaaccat tgattgggat aagaaagttg caccaagtgc tatctacgaa
     5221 gaaggtgcag tggtctttcc agtccttcac gggccaatgg gagaagatgg ctctgttcaa
     5281 ggattcttgg aagttttgaa aatgccttac gttggttgca acattttgtc atcaagtctt
     5341 gccatggata aaatcacgac taagcgtgtt ctggaatctg ctggtattgc ccaagttcct
     5401 tatgtggcta tcgttgaagg cgatgatgtg actgctaaaa tcgctgaagt ggaagaaaaa
     5461 ttggcttatc cagtcttcac taagccgtca aacatggggt ctagtgtcgg tatttctaag
     5521 tctgaaaacc aagaagaact ccgtcaagcc ttaaaacttg ccttccgata tgacagccgt
     5581 gtcttggttg agcaaggagt gaatgcccgt gaaattgagg ttggcctctt gggtaactac
     5641 gatgtcaaga gcacgctacc aggagaagtt gtcaaggacg ttgcctttta tgactacgat
     5701 gccaagtata ttgataacaa tattactatg gatattcctg ccaaaatcag tgatgatgtg
     5761 gtggctgtca tgcgtcaaaa tgcagaaaca gccttccgtg ccattggtgg ccttggtcta
     5821 tctcgttgcg atttcttcta tacagataag ggagagattt ttctcaacga gctcaatact
     5881 atgccaggtt tcacccagtg gtctatgtac ccactacttt gggacaatat ggggatcagc
     5941 tacccaaaac taatcgagcg tttggttgac cttgccaagg aaagttttga caagcgcgaa
     6001 gcgcatttga tataaaatga aagagagggt agaagccaga accatcactg caaggtgact
     6061 agagttctcg gacttcagcc ctttttaaag gagtagaaat gaaattaaca atccatgaaa
     6121 ttgcccaagt tgttggagcc aaaaatgata tcagtatctt tgaggacacc cagttagaaa
     6181 aagctgagtt tgatagtcgt ttgattggaa ctggagattt atttgtgcca cttaaaggtg
     6241 cgcgtgatgg ccatgacttt attgaaacag cctttgaaaa tggtgcagca gtaaccttgt
     6301 ctgagaaaga ggtctcaaat catccttaca ttctagtaga tgatgttttg acagcctttc
     6361 aatccttagc atcctactat cttgaaaaaa cgactgttga tgtctttgct gttacaggtt
     6421 caaatggcaa gacaacgact aaggatatgt tggcgcattt actgtcaaca agatacaaga
     6481 cctacaaaac acaaggcaat tacaataatg agattggcct tccttacaca gttcttcata
     6541 tgcctgaagg aacagaaaag ttggttttgg agatgggaca ggatcacttg ggcgatattc
     6601 atctcttgtc tgaattggct cgtccaaaaa cagccatcgt gaccttggtt ggagaagccc
     6661 atttggcctt tttcaaagac cgttcagaga ttgctaaggg aaaaatgcaa attgcagacg
     6721 gaatggcttc aggttccttg cttttagcgc cggctgaccc tatcgtagag gactatttgc
     6781 caactgataa aaaggtggtt cgttttgggc aaggggcaga gctggaaatt actgacttgg
     6841 ttgagcgcaa agatagtctg accttcaagg ccaatttctt agagcaagcc cttgatttgc
     6901 cagtaactgg caagtacaat gcgacaaatg ctatgattgc atcctatgtt gccttgcaag
     6961 aaggagtttc agaggagcaa attcgtttgg ccttccaaga tcttgaattg acgcgtaacc
     7021 gtaccgagtg gaagaaagca gccaatggag cagatatcct gtcagatgtt tacaatgcca
     7081 atccaactgc tatgaaactg attttagaga ctttctctgc cattccagcc aatgaaggtg
     7141 gcaagaaaat tgcagtgttg gcggatatga aggagcttgg tgaccagtct gttcaacttc
     7201 ataatcagat gattttgagc ctttctccag atgtgcttga taccgtgatt ttctatggac
     7261 aagatattgc tcagttggct caattggcca gtcaaatgtt cccaatcggc cacgtttact
     7321 acttcaagaa aacagaagac caggatcaat ttgaagacct agtcaagcag gtcaaggaaa
     7381 gccttggagc ccatgaccaa atcctgctca aaggctctaa ctctatgaat ctagccaagt
     7441 tggtagaaag tttagaaaat gaagacaagt gattttgtca agtatttgca aagaatgatt
     7501 gccattacag atactggctt aacctttaca aaagatccgt ttgaccgtga gcgctacgaa
     7561 gacttgcgaa gtctgttatc tgaaatgttg aatcaagcat cagaccttga ttccgaagaa
     7621 gtggcagaag tcttgaagcc aacttctgct tatgcgactc cgttaatgga cgtccgtgct
     7681 tggattgttg aggatgagaa gatttgtctg gttaggggac aaggagagga tagttgggct
     7741 ttgccaggtg gctttggtga agtcggctat tctccaacag aaaatattct caaggaaatt
     7801 gaagaagaaa ccggttttaa agccaaagtt gaaagactgc tagctgtttt tgataccaat
     7861 cgtttccaac tacagagcaa acagtataca aagtttgttt ttggatgtaa gcttcttgat
     7921 ggacaattcc aagaaaatca agaaattgct gaccttcaat tttttgccat tgaccaactg
     7981 ccgaacttat ctgaaaaacg cattaccaag gagcaaatag agcttctttg gcaggtttat
     8041 caaggtcata gggggcaata tcttgactaa gaagatgatt atcgtatttc taaatccatt
     8101 tttaacaact agcatggtat aataatatgc aggaaaattt tgaattatga ggaagactag
     8161 atgaatttat gggatatttt ctttacgact caggcaaccg agccgcccaa atttgacctt
     8221 ttttggtatg ttagcctatt tacgctctta gccttaacct tttatacagc ccatcgctat
     8281 cgtgaaaaga aggtttacca acgatttttc caaatcttgc agactgttca gttaatcctt
     8341 ctttatggtt ggtactgggt caatcatatg ccactgtcag aaagcctacc cttttaccat
     8401 tgccgtatgg ctatgtttgt ggtactcttg cttcctggtc aatccaaata taaacaatac
     8461 tttgcattat tgggaacatt tgggacatta gcagcctttg tttatccagt gccagatgct
     8521 tacccttttc cacatatcac cattctatcc tttatctttg gtcatttagc actcttgggg
     8581 aactctctag tttatctatt gagacagtat aatgcgcgat tgctggatgt gaagggaatt
     8641 tttctcatga cctttgccct aaatgccttg atttttgtgg tcaatttggt gacaggtggc
     8701 gattacggat ttttgacaaa accgccattg gttggggatc acggtctagt agctaattat
     8761 ttacttgttt caattgtgct ggtagctact atcagtttga ctaagaaaat cttagaattc
     8821 tttttagctc aagaagcaga aaaaatgatt gcaaaggaag cttaacacag agctttcttt
     8881 tttgctctta gagagttttt acaagcagct tataaaataa gaatttctga atagacaaac
     8941 tcaaaaaatg gctgggaaat ttaggaaaaa agcaagcacg attaaatttt ttgtgttata
     9001 atattttgtg aatagctatg cctatgttta gctatggaat aatacgaagt gcgaaacttg
     9061 gaagatagag aggaagcgat gtaatggcta gagaaggctt ttttacaggt ctagatattg
     9121 gaacaagctc tgtcaaggtg cttgtggccg agcagagaaa tggtgaatta aatgtaattg
     9181 gcgtgagtaa tgccaaaagt aaaggtgtaa aggatggaat tattgttgat attgatgcag
     9241 cagcaactgc tatcaagtca gccatttccc aagcggaaga aaaggcaggc atttcgatta
     9301 aatcagtgaa tgtcggcttg cctggtaatc ttttgcaggt agaaccaact caggggatga
     9361 ttccagtaac atctgatact aaggaaatta cggatcaaga tgttgaaaat gttgtcaaat
     9421 cagctttgac aaagagtatg acacctgacc gtgaagtcat tacctttatt cctgaagaat
     9481 ttattgtgga tggtttccaa gggattcgtg acccacgtgg catgatgggg gttcgccttg
     9541 aaatgcgtgg tttgctttat acaggacctc gtactatctt gcacaatttg cgtaagacgg
     9601 ttgagcgtgc aggtgttcag gttgaaaatg ttatcatttc accactagca atggttcagt
     9661 ctgttttgaa cgaaggggaa cgtgaatttg gtgctacagt gattgatatg ggggcaggtc
     9721 aaacgactgt cgctacaatc cgtaatcaag aactccagtt cacacatatt ctccaagaag
     9781 gtggagatta tgtaactaaa gatatctcca aggttttgaa aacctctcgc aaattagcgg
     9841 aaggcttgaa actgaattac ggggaagcct atccgcctct tgcaagcaaa gaaaccttcc
     9901 aagtagaggt tattggagaa gtagaagcag tcgaagtgac ggaagcctac ttgtcagaaa
     9961 ttatttctgc acgaatcaag cacatccttg aacaaatcaa gcaagaatta gatagaaggc
    10021 gtctattgga cctccctggt ggtattgtct taatcggtgg gaatgccatt ttaccaggta
    10081 tggttgagct tgctcaggaa gtctttggcg tccgtgtcaa gctttatgtt ccaaatcaag
    10141 ttggtatccg taatccagcc tttgcgcatg tgattagttt atcagaattt gcgggtcaat
    10201 taacagaagt taatcttttg gctcagggag cgataaaagg tgagaatgac ttaagtcatc
    10261 agccaattag ttttggtggg atgctgcaaa aaacagctca gtttgtacaa tcaacgcctg
    10321 ttcaaccagc tcctgctcca gaagtagagc cggtggcgcc tacagaacca atggcggatt
    10381 tccaacaagc ttcacaaaat aaaccgaaat tagcagatcg tttccgtgga ttgatcggaa
    10441 gcatgtttga cgaataaaga ggaaaaataa attatgacat tttcatttga tacagctgct
    10501 gctcaagggg cagtgattaa agtaattggt gtcggtggag gtggtggcaa tgccatcaac
    10561 cgtatggtcg acgaaggtgt tacaggcgta gaatttatcg cagcaaacac agatgtacaa
    10621 gcattgagta gtacaaaagc tgagactgtt attcagttgg gacctaaatt gactcgtggt
    10681 ttgggtgcag gaggtcaacc tgaggttggt cgtaaagccg ctgaagaaag cgaagaaaca
    10741 ctgacggaag ctattagtgg tgccgatatg gtcttcatca ctgctggtat gggaggaggc
    10801 tctggaactg gagctgctcc tgttattgct cgtatcgcca aagatttagg tgcgcttaca
    10861 gttggtgttg taacacgtcc ctttggtttt gaaggaagta agcgtggaca atttgctgta
    10921 gaaggaatca atcaacttcg tgagcatgta gacactctat tgattatctc aaacaacaat
    10981 ttgcttgaaa ttgttgataa gaaaacaccg cttttggagg ctcttagcga agcggataac
    11041 gttcttcgtc aaggtgttca agggattacc gatttgatta ccaatccagg attgattaac
    11101 cttgactttg ccgatgtgaa aacggtaatg gcaaacaaag ggaatgctct tatgggtatt
    11161 ggtatcggta gtggagaaga acgtgtggta gaagcggcac gtaaggcaat ctattcacca
    11221 cttcttgaaa caactattga cggtgctgag gatgttatcg tcaacgttac tggtggtctt
    11281 gacttaacct tgattgaggc agaagaggct tcacaaattg tgaaccaggc agcaggtcaa
    11341 ggagtgaaca tctggctcgg tacttcaatt gatgaaagta tgcgtgatga aattcgtgta
    11401 acagttgttg caacgggtgt tcgtcaagac cgcgtagaaa aggttgtggc tccacaagct
    11461 agatctgcta ctaactaccg tgagacagtg aaaccagctc attcacatgg ctttgatcgt
    11521 cattttgata tggcagaaac agttgaattg ccaaaacaaa atccacgtcg tttggaacca
    11581 actcaggcat ctgcttttgg tgattgggat cttcgccgtg aatcgattgt tcgtacaaca
    11641 gattcagtcg tttctccagt cgagcgcttt gaagccccaa tttcacaaga tgaagatgaa
    11701 ttggatacac ctccattttt caaaaatcgt taagtaaatg aatgtaaaag aaaatacaga
    11761 acttgttttt cgagaagttg cagaggctag tctgagtgct catcgagaga gtggttcggt
    11821 ctctgtcatt gcagttacca agtatgtaga tgtaccgaca gcggaagcct tgcttccgct
    11881 aggtgttcat catatcggtg aaaatcgtgt agataagttt ctggaaaaat atgaagcttt
    11941 aaaagatcga gatgtgactt ggcatttgat tggtaccttg caaagacgta aggtgaaaga
    12001 tatcattcaa tacgttgatt atttccatgc attggactca gtaaagctag caggggaaat
    12061 tcaaaaaaga agtgaccgag tcatcaagtg tttccttcaa gtaaatattt ctaaagaaga
    12121 aagcaaacac ggtttttcga gagaggaact gctggaaatc ttgccagagt tagccagact
    12181 agataagatt gaatatgttg gtttaatgac gatggcacct tttgaggcta gcagtgagca
    12241 gttgaaagag attttcaagg cggcccaaga tttacaaaga gaaattcaag agaaacaaat
    12301 tccaaatatg cctatgaccg agttaagtat gggaatgagt cgtgattata aagaagcgat
    12361 tcaattcggt tccacttttg ttcgtatagg tacatcattt tttaagtagg agagaaccat
    12421 gtctttaaaa gatagattcg atagatttat agattatttt acggaggatg aggattcaag
    12481 tctcccttat gaaaaaagag atgagcctgt gtttactcca gtaaattctt cacaggaacc
    12541 ggctctccca atgaatcaac cttcacagtc ggctggtaca aaagagaaca atatcaccag
    12601 acttcatgca agacaacagg aattggcaaa tcagagtcag cgtgcaacgg ataaggtcat
    12661 tatagatgtt cgttatccta gaaaatatga ggatgcaaca gaaattgttg atttattggc
    12721 aggaaacgaa agtatcttga ttgattttca gtatatgaca gaggtgcagg ctcgtcgttg
    12781 tttggactat ttggatggag cttgtcatgt tttagctgga aatttgaaaa aggtagcttc
    12841 taccatgtat ttgttgacac cagtgaatgt tattgtaaat gttgaagata tccgtttacc
    12901 agatgaagat caacagggtg agttcggttt tgatatgaag cgaaatagag tacgataatg
    12961 atttttttaa ttcgtatgat ttataatgca gtggatattt actccctgat tttggtagcc
    13021 ttcgctgtca tgtcttggtt tccaggtgcc tacgaatcca gtttaggtcg ttggattgta
    13081 gcgttggtga aaccagtgct tgctcccttg caacgcctgc ctttacagat agcgggtctt
    13141 gatttatctg tttgggtcgc gattgttttg gttcgatttt taggagaaaa cctagtgcgt
    13201 tttctggcga tgataggatg aataaaggga tttatcagca tttctccata gaagatcgtc
    13261 catttcttga caagggaatg gaatggataa agaaggtaga agatagctat gctccttttt
    13321 taactccttt tatcaatcct catcaggaga agctattaaa gattttggcc aaaacatatg
    13381 gtcttgcttg tagcagtagt ggggaattcg tctcgagtga gtatgttcga gttttattat
    13441 acccagatta tttccaacca gagttttcag attttgaaat atctctccag gaaattgtgt
    13501 attccaataa atttgaacat ttaacgcatg ctaagatttt agggacagtc atcaatcaat
    13561 tagggattga acggaaactt tttggagata tcctagtaga tgaagaacgg gcgcagatta
    13621 tgattaatca gcagtttctt cttctctttc aagatggact aaagaaaatt ggtcgtatac
    13681 ctgtttcgct ggaggaacgt cctttcaccg agaaaataga taagctagaa cagtatcgag
    13741 aactggattt atctgtgtct agttttcgat tagatgttct tttatcaaat gttttgaaac
    13801 tatctaggaa tcaagcaaac cagttgattg aaaagaaact tgtccaagta aattatcatg
    13861 tggtagacaa atcagattac actgttcaag ttggagactt gattagtgtg agaaaatttg
    13921 gtcgcttgag attacttcaa gataagggac aaacgaaaaa agagaagaaa aaaataaccg
    13981 tccagttatt attaagtaag tgaggaatag aatgccaatt acatcattag aaataaagga
    14041 caagactttt ggaactcgat tcagaggttt tgatccagaa gaagtcgatg aatttttaga
    14101 tattgtggtt cgtgattacg aagatcttgt gcgtgcgaat catgataaaa atttgcgtat
    14161 taagagttta gaagagcgtt tgtcttactt tgatgaaata aaagattcat tgagccagtc
    14221 tgtattgatt gctcaggata cagctgagag agtgaaacag gcggcgcatg aacgttcaaa
    14281 caatatcatt catcaagcag agcaagatgc gcaacgcttg ttggaagaag ctaaatataa
    14341 ggcaaacgag attcttcgtc aagcaactga taatgctaag aaagtcgctg ttgaaacaga
    14401 agaattgaag aacaagagcc gtgtcttcca ccaacgtctc aaatctacaa ttgagagtca
    14461 gttggctatt gttgaatctt cagattggga agatattctc cgtccaacag ctacttatct
    14521 tcaaaccagt gatgaagcct ttaaagaagt ggttagcgaa gtacttggag aaccgattcc
    14581 agctccaatt gaagaagaac caattgatat gacacgtcag ttctctcaag cagaaatgga
    14641 agaattacaa gctcgtattg aggtagccga taaagaattg tctgaatttg aagctcagat
    14701 taaacaggaa gtggaagctc caactcctgt agtgagtcct caagttgaag aagagcctct
    14761 gctcatccag ttggcccaat gtatgaagaa ccagaagtag ctccagtgca tccgacaggt
    14821 ccaacaccag ctacagaaac tgttgattca gcaccgggat ttgaagcacc gcaagaatct
    14881 gttacaattt tataagaaat attctgagaa caatatctta tccttatatt tccagcgagc
    14941 aggagatggt gtgagtcctg cattccctat cgataagatt atcctctcaa aaactcaagt
    15001 ctgaatctag taagatttga cgttccccac gttacgggat aagagggaga aagactaaaa
    15061 ctttttccga ataaaggtgg taccacgatt ttcgtccttt ttggaagtcg tggtttttaa
    15121 tttgttatta tttataaagg agataccatg aaactcaaag acacccttaa tcttgggaaa
    15181 actgaattcc caatgcgtgc aggccttcct accaaagagc cagtttggca aaaggaatgg
    15241 gaagatgcaa aactttatca acgtcgtcaa gaattgaacc aaggaaaacc tcatttcacc
    15301 ttgcatgatg gccctccata cgctaacgga aatatccacg ttggacatgc tatgaacaag
    15361 atttcaaaag atatcattgt tcgttctaag tctatgtcag gattttacgc accatttatt
    15421 cctggttggg atactcatgg tctgccaatc gagcaagtct tgtcaaaaca aggtgtcaaa
    15481 cgtaaagaaa tggacttggt tgagtacttg aaactttgcc gtgagtacgc tctttctcaa
    15541 gtagataaac aacgtgaaga ttttaaacgt ttgggtgttt ctggtgactg ggaaaatcca
    15601 tatgtgacct tgactcctga ctatgaagca gctcaaattc gtgtatttgg tgagatggct
    15661 aataagggtt atatctaccg tggtgccaag ccagtttact ggtcatggtc atctgagtca
    15721 gcccttgctg aagcagagat tgaataccat gacttggttt caacttccct ttactatgcc
    15781 aacaaggtaa aagatggcaa aggagttcta gatacagata cttatatcgt tgtctggaca
    15841 acgactccat ttaccatcac agcttctcgt ggtttgacgg ttggtgcaga tattgattac
    15901 gttttggttc aacctgctgg tgaagctcgt aagtttgtcg ttgctgctga attattgact
    15961 agcttgtctg agaaatttgg ctgggctgat gttcaagttt tggaaactta ccgtggccaa
    16021 gaactcaacc acatcgtaac agaacaccca tgggatacag ctgtagaaga gttggtaatt
    16081 cttggtgacc acgttacgac tgactctggt acaggtattg tccatacagc ccctggtttt
    16141 ggtgaggacg attacaatgt tggtattgct aataatcttg aagtcgcagt gactgttgat
    16201 gaacgtggta tcatgatgaa gaatgctggt cctgaatttg aaggtcaatt ctatgaaaag
    16261 gtagttccaa ctgttattga aaaacttggt aacctccttc ttgcccaaga agaaatctct
    16321 cactcatatc catttgactg gcgtactaag aaaccaatca tctggcgtgc agttccacaa
    16381 tggtttgcct cagtttctaa attccgtcaa gaaatcttgg acgaaattga aaaagtgaaa
    16441 ttccactcag aatggggtaa agtccgtctt tacaatatga tccgtgaccg tggtgactgg
    16501 gttatctctc gtcaacgtgc ttggggtgtt ccacttccta tcttctacgc tgaagatggt
    16561 acagctatca tggtagctga aactattgaa cacgtagctc aactttttga agaacatggt
    16621 tcaagcattt ggtgggaacg tgatgccaaa gacctcttgc cagaaggatt tactcatcca
    16681 ggttcaccaa acggcgagtt caaaaaagaa actgatatca tggacgtttg gtttgactca
    16741 ggttcatcat ggaatggagt ggtggtaaac cgtcctgaat tgatttaccc agccgacctt
    16801 tacctagaag gttctgacca ataccgtggt tggtttaact catcacttat cacatctgtt
    16861 gccaaccatg gcgtagcacc ttacaaacaa atcttgtcac aaggttttgc ccttgatggt
    16921 aaaggtgaga agatgtctaa atctcttgga aataccattg ctccaagcga tgttgaaaaa
    16981 caattcggtg ctgaaatctt gcgtctctgg gtaacaagtg ttgactcaag caatgacgtg
    17041 cgtatctcta tggatatttt gagccaagtt tctgaaactt accgtaagat tcgtaacact
    17101 cttcgtttct tgattgccaa tacatctgac tttaacccag ctcaagatac agtcgcttac
    17161 gatgagcttc gttcagttga taagtacatg acgattcgct ttaaccagct tgtcaagacc
    17221 attcgtgatg cctatgcaga ctttgaattc ttgacgatct acaaggcctt ggtgaacttt
    17281 atcaacgttg acttgtcagc cttctacctt gattttgcca aagatgttgt ttacattgaa
    17341 ggtgccaaat cactggaacg ccgtcaaatg cagactgtct tctatgacat tcttgtcaaa
    17401 atcaccaaac tcttgacacc aatccttcct cacactgcgg aagaaatttg gtcatatctt
    17461 gagtttgaaa cagaagactt cgtccaattg tcagagttac cagaggttca aacttttgct
    17521 aatcaagaag aaatcttgga tacatgggca gccttcatgg acttccgtgg acaagcacaa
    17581 aaagccttgg aagaagctcg taatgcaaaa gttatcggta aatcacttga agcacacttg
    17641 acagtttatc caaatgaagt tgtgaaaact ctactcgaag cagtaaacag caatgtagct
    17701 caacttttga tcgtgtctga gttgaccatc gtagaaggac cagctccgga agctgccctt
    17761 agcttcgaag atgtagcctt cacagttgaa cgtgctactg gtgaagtatg tgaccgttgc
    17821 cgtcgtatcg acccaacaac agcagaacgc agctaccagg cagttatctg tgaccactgt
    17881 gcaagcatcg tagaagaaaa ctttgcggaa gcagtcgcag aaggatttga agagaaataa
    17941 gattgaaaag tctaggcaaa attcaatttg agaagaaaag acaactaatt ttatagtcta
    18001 ttaaacgcat tgtatcacgt ttttgaatac ctgatatgat gcgtttttta tttattttaa
    18061 aaatttgcga ggtatgactt tttatactca acaagaatca aagagaaact tagcaatcta
    18121 acagtagtaa gataaaatag gaatttgata ttagggataa gattggtaaa tagtgtaata
    18181 tttttacaac aataaattta tatagttatt tctggtttct gaaaagtatt atattttatt
    18241 tcatattata caaattttta ttttataata tcagaacata ctttttttaa aagcaaatat
    18301 gatacaattt tatttgaaaa aaataaaaaa ggagatttta ttataaaatt aaaaagactt
    18361 gctttaatta gtggtatcgt cggtcttgtg ggaggaattt tacttcttat tggtcctttt
    18421 gtcttgttgg gaacagcggt aaacacagct gctacaactc ttaatggagg agctactgca
    18481 ggggcttttt caggtgtagc cttactcttg aatgccttga agattgcaaa tcttgttctt
    18541 ggtatcattg ctattgttta ctataaagga gataagcgtg taggtgcagc tccgtctgta
    18601 ctaatgattg tttctggtgg agttagtctc attccattct taggatgggt tggggggatt
    18661 cttgctatta tcggaggatc tctattcctt gcaacattga agaaattcaa atcagaagaa
    18721 taaaaggtat tttagcatga aaagaacaaa aaagtttatc ggtataggag tagctctatt
    18781 atctctttct cttctagttg catgtggaac ataaagttca aagaatactt caacaagtaa
    18841 tgatgagaag acagtagcaa catccaatag ttcaaaagaa acaatcactt tcgatatacc
    18901 ggttgtaaca gacgatgcga ttgaatcaat acgcacttat gcagattata tagatcttta
    18961 taaaaatatt tttgatgatt attttactaa agctgaggaa ggtttcaaag gcacagctat
    19021 ggaaaataat gactcgttta ctaaactaaa agagtcaact caaaaattat tcgatgcgca
    19081 gaaaaaaggt taaataatga agatagaata gaaacagcca aaaacaatgt gattgccaaa
    19141 cattgtcaaa cagtcctttc ctttttggtt ttgactagct tttttgtgaa aaattgtgta
    19201 aaatagaata gataaacgag gggaaacctc ggaaaattta aaggagaatc catctaatgg
    19261 taaaattggt ttttgctcgc cacggtgagt ctgaatggaa caaagctaac cttttcactg
    19321 gttgggctga tgttgatttg tctgaaaaag gtacacaaca agcgattgac gctggtaaat
    19381 tgatcaaaga agctggtatc gaatttgacc aagcttacac ttcagtattg aaacgtgcta
    19441 tcaaaacaac taacttggct cttgaagctt ctgaccaatt gtgggttcca gttgaaaaat
    19501 catggcgctt gaacgaacgt cactacggtg gtttgactgg taaaaacaaa gctgaagctg
    19561 ctgaacaatt tggtgatgag caagttcaca tctggcgtcg ttcatacgat gtattgcctc
    19621 caaacatgga ccgtgatgat gagcactcag ctcacacaga ccgtcgttac gcttcacttg
    19681 acgactcagt tatcccagat gctgaaaact tgaaagtgac tttggaacgt gctcttccat
    19741 tctgggaaga taaaatcgct ccagctctta aagatggtaa aaacgtattc gtaggagctc
    19801 acggtaactc aatccgtgcc cttgtaaaac acatcaaagg tttgtcagat gacgagatca
    19861 tggacgtgga aatccctaac ttcccaccat tggtattcga attcgacgaa aaattgaacg
    19921 tcgtttctga atactacctt ggaaaataaa aaattgtaag tctagaattg atttctaggc
    19981 tttttatgtt agtatggaag tatgataagg aataaaaaac aagattatgt actggcctac
    20041 aagcaaccag cttcaaccac ttacatgggt tgggaagaag aagctttacc gataggtaat
    20101 ggttctttag gagcaaaagt atttggcctt ataggggctg aacggattca atttaatgaa
    20161 aaaagtctct ggtctggagg tccacttcct gatagttcag attatcaggg tggaaatctt
    20221 caggatcagt atgttttttt agctgagatt cggcaggctt tggagaagag agattacaat
    20281 ctggctaagg aactggctga gcagcaccta attgggccaa aaacgagtca atatgggacc
    20341 tatctgtctt ttggggatat tcacattgag ttcagccagc aaggtacgac tttgtctcag
    20401 gtgacggact atcagagaca gttgaatatt agtaaggcac ttgcgacgac ttcttatgtc
    20461 tataagggaa cgcgatttga acgtgaagct tttgcgagtt ttccagatga tctcttggtt
    20521 caatgtttta ctaaggaagg gttggaaact ctagatttta ctatagaact atccttgacc
    20581 tgtgatttgg cttctaatgg aaagtatgag caggaaaaat ctgattacaa ggagtgtaag
    20641 ttggatatta ctgattctca tatcttgatg aagggaagag ttaaggataa tgatctgcgg
    20701 tttgctagtt atctagcttg ggaaacggat ggagatatta gagtttggtc agatagggtt
    20761 cagatatcag gagccagtta tgccaatctc ttcttggccg ctaagacgga ttttgcccaa
    20821 aatcctgcta gcaattatcg caagaaacta gatttagagc aacaggtgat agacttggtg
    20881 gacacagcta aagaaaaggg ctatacccaa ttgaaatcaa ggcatatcga ggactaccaa
    20941 gccttattcc agcgtgttca attggatttg gaagctgatg ttgacgcatc cactacagat
    21001 gatttgttaa aaaattataa gccacaagaa gggcaggctt tggaggagct gttcttccag
    21061 tatggacggt atttattgat tagttcgtcc agagactgcc cagatgctct accagctaac
    21121 ctacagggag tctggaatgc ggtcgacaat cctccttgga attcggacta tcacttaaat
    21181 gtcaatctgc agatgaatta ttggccagcc tatgttacca atctcctaga gacggtcttt
    21241 ccagtcatca actatgtaga tgatttgcgt gtctatggtc gtctagcggc tgtaaagtat
    21301 gcaggaatcg tctctcagaa aggtgaggag aatggttggt tggttcatac tcaagcgact
    21361 ccctttggtt ggacggcacc tggttgggat tactattggg gttggtcacc agctgccaat
    21421 gcgtggatga tgcaaaccgt ttatgaagcc tattcatttt atagggacca agactatctc
    21481 agggagaaaa tttatcccat gttgagggaa acggttcgtt tttggaatgc ctttttacat
    21541 aaggatcagc aggcgcagcg ttgggtgtct tctccgtctt attccccaga acatgggccg
    21601 atttcgattg gcaatactta tgaccaatct ctgatttggc agttatttca tgattttatt
    21661 caggctgctc aggaattggg actggatgag gacttgttga ctgatgttaa ggagaagtct
    21721 gatttactaa atcctttgca aatcactcaa tctggtcgaa tcagggagtg gtatgaggag
    21781 gaagagcagt attttcaaaa tgagaaagtg gaggcccagc atcggcatgc ttcccatcta
    21841 gtgggactct atcctggcaa tctctttagc tacaagggac aagagtatat tgaagcggcg
    21901 cgtgctagcc tcaatgatcg tggaaatggc ggcacaggct ggtccaaggc taataagatc
    21961 aatctctggg cgcgtttggg agatggcaat cgagcccata aattattggc agagcagtta
    22021 aagacatcca ccttgccaaa tctttggtgt agccatcctc cttttcagat agatggtaat
    22081 tttggtgcta ctagtggcat ggcagaaatg ttactccagt ctcatgcagc ttatctggta
    22141 cctctagctg ccctacctga tgcttggtca acaggttctg tttcaggctt aatggcacgt
    22201 ggacattttg aagtgagcat gagctgggaa gataaaaaac tcttacagtt gaccatttta
    22261 tcaaggagtg gaggagattt gcgagtttct tatccagata ttgagaagag tgtgattaaa
    22321 atgaatcaag aaaaaataaa agcgaaatgc atggggaaag attgtatttc ggtggcaaca
    22381 gcagaaggtg atcttgttca attttatttt taagaagatg ttataaggca gtaatttgaa
    22441 actgcctttt aataaggatt taagaatata agcagttttc aactagttga aaaagcgtta
    22501 taatgataat aggaagtaat actcaatgaa aatcaaagag cacaaacaag gaagctagcc
    22561 gcaggttgct caaaacagtg ttttgaggtt gcagatggaa gctgacgtgg tttgaagaga
    22621 gattttcgag gagtataatt tgtttgatag agggtgggtc tgatggctta tattgagatg
    22681 aaacactgtt acaagcgtta tcaggttggg gacacggaga ttgtggccaa tcgtgatgtg
    22741 aattttgaga ttgaaaaggg ggagctggtt attatccttg gtgcttcagg tgcaggcaag
    22801 tcaacagttc ttaaccttct tgggggaatg gataccaatg atgaagggga aatctggatt
    22861 gatggtgtta atattgcgga ttatagttcc caccagcgca ccaattaccg tagaaatgat
    22921 gtggggtttg tttttcagtt ttataatcta gtttctaatc tgacagctaa ggaaaatgtg
    22981 gaactggctt ctgaaattgt gacagatgcc ttgaatcctg atcaggtctt gacagatgta
    23041 ggtctggctc atcgtctcaa taactttcca gcccagcttt ctggagggga gcaacagcga
    23101 gtctccattg cacgcgcggt agccaaaaat cctaaaattc tcctttgtga tgaaccgact
    23161 ggagccttgg attatcagac gggcaagcag gttttgaaaa ttctccaaga catgtctcgt
    23221 caaaagggag cgacggtgat catcgtgact cataatggag ctttggcgcc cattgctgat
    23281 cgcgtgattc atatgcacga tgccagtgtc aaggatgtgg tgctcaacca gcatcctcag
    23341 gatattgaca gtttggagta ctagcatgat caagcgaaaa acttattgga aggacttaat
    23401 tcagtccttc acagactcca aggggcgttt tttatccatc ttgatcctga tgatgttggg
    23461 atctctagcc ttagtaggcc tcaaagtaac cagtcccaac atggaggcga cagctaatgc
    23521 ttatttaaca actgctcaaa ccttggattt ggcagtcatg tctaactatg gcttggatca
    23581 agcagaccaa gaagaactaa aacagacgga gggcgcagag gtcgagtttg gctatttgac
    23641 agatgtgact atggataatg ggcaggatgc cattcggctg tactccaaac cagagcgaat
    23701 ttcaaccttt cagctaagaa agggacgact tcctcagtca gacaaggaaa tcgctttggc
    23761 cactcatttg caaggccaat acagcgtggg acaggagatt agttttaaag aaaaagaaga
    23821 gggtcattcc tctttaaaag accatactta taccattact ggttttgtgg attcggctga
    23881 aatcctctcc cagcgagata tgggctacgc aggaagtgga agtgggactc tgacagccta
    23941 tggggtgatt ttacctagtc aatttgatca gaaagtctac aatatagctc gtttgaaata
    24001 tcaagattta gcaggtttaa atgccttttc atcagcttat gaagaaaaat ccaagcaaca
    24061 tcaggaagag cttgaacaaa ttttatcaga taatggcaag gtacgtctgc aacttttgaa
    24121 aaaagaagga caagagtctc tagacaaggg gcaagagacc cttgacaagg ctcagactaa
    24181 tttgcaggaa ggcaagcgtc gtttagcagc tgctcaagct cgtatacagg ctcaagaaag
    24241 tcaactagcc ttgtttcctc aagttcagag agagcaggct agtgctcaac ttacccaagc
    24301 caagcaggaa ttgggcaagg aagaggccaa actaaagcaa gctgaacaaa atctagccca
    24361 agaaaaggaa aaattagaaa aacatcagca agtcttggac gatttggcgg agccaaggta
    24421 tcaggtctat aatcgtcaga ccatgccagg tggtcagggc tatcttatgt atagcaatgc
    24481 ttcatccagt attcgagcag tgggcaatat ctttcctgtg gtactttatg ccgtagcagc
    24541 catggtgacc tttacgacca tgactcgctt tgtagacgaa gagcgaactc atgcagggat
    24601 ttttaaggcc ttgggttatc gtagtaagga tattatcgcc aagtttctcc tttatggact
    24661 agtagctggg actgtcggaa cggctctagg tagtatactt ggtcattatt tgctagccaa
    24721 tgtaatttca agtgtcatta caaaaggcat ggtggtggga gaaactcaga ttcagttcta
    24781 ttggacctat agcttactag ctcttgtctt gagcttgttg gcgagtgtgt taccagccta
    24841 tctggtggct tggagggaac ttcatgacga agcagcccag cttctacttc ctaaacctcc
    24901 tgtcaaagga gctaaaatat tattggagcg tatcggtttt atctggcgtc gtctcagttt
    24961 tactcataag gtaacagccc gcaacatctt tcgttataag cagagaatgt tgatgacaat
    25021 ctttggtgtg gcaggttctg tagctctgct ctttgcaggt ttgggaatcc aatcttctgt
    25081 agcaggagtt ccgtctaaac agtttcaaca aatccaacag tatcagatgc ttgtctctga
    25141 aaatcctagt gcgaccaatc aggacaaggt agagctagca gaagtgttga aagggcagga
    25201 gatactagcc taccagaaaa tctattctaa aacgctagac aaggatttca aaggcaaggc
    25261 tggtcttcaa aacattactc ttatgatgat agagaaggaa gatttgactc cctttatcca
    25321 tcttcaacat catcagcagg agctgacatt aaaagatggc atcgttatta cagctaaact
    25381 cgcccagctg gcaggtgtca aggttgggca gactttagaa attgaaggta aggaactaaa
    25441 ggtcgctgct attactgaga actacgttgg tcactttatt tatatgagtc aggctagcta
    25501 tgagcaactt tacggacagc taccccaagc caacacttat ctggtctcat taagggatac
    25561 cagtgcaact agtatcgaaa gtcaggcggg cttgcttatg aatcaatctg cggtgtccag
    25621 cgttgtccaa aatgcttcag ccattcgact cttcgactct atcgctagct cactcaatca
    25681 gaccatgacc atcttggtca tcgtatcggt tctattagct attgtcatcc tttacaatct
    25741 gaccaatatc aacgtagctg agagaatccg tgaactctcc actatcaagg ttctcggttt
    25801 tcataataat gaagtcaccc tctacattta tcgtgagacg attgtgctgt cccttgtggg
    25861 aatcgtactt ggtctggtag ctggtttcta tttacaccaa tttttgattc aaatgatttc
    25921 gcctgcgact attctctttt atccgcagat aggctgggaa gtctatgtaa tcccagtggc
    25981 agcagtaagc atcattttga ccttgcttgg tttcttcgtc aattattatc tgagaaaggt
    26041 tgatatgtta gaagccctga aatctgtaga gtaaggtagt tatttttagc tgattgaact
    26101 tctatttact aatattcaaa aatcctccgt ttcaaagagc agggaactct ttgtgacaga
    26161 ggattttttc tatagggctt tagcagctgc aattgcggct tcgaagtttg gctcagaatt
    26221 gatattatcc acgtattcaa cgtagcgaat cgtattgtca gtatcgagga caaagactgc
    26281 gcgtgctaat aggtgccatt cgttgatcaa gagggcataa tcgcgcccga aagaatggtc
    26341 aaagtagtct gaaagcataa tggcattgtc aaggccttca gcaccgcacc aacgtttttg
    26401 agcaaaaggt aggtccattg aaacagtcaa tacgaccgtg ttgtccagtc cagccaattc
    26461 ttcattaaaa cgacgtgttt gagttgagca gatgcctgta tcgatagaag gaacgacact
    26521 caagactttt ttcttgccat caaaatcagc cagagatttt ttagaaagat ctgttgtagt
    26581 aagagaaaaa tcaagcgcct tgtcgccgac ttgtagttgt ttacctgtaa agctcacagg
    26641 atttccgaga aaagttacca taggatactc caatcttttt tcttccattg tatctgaaac
    26701 agtcagaatt ttccaatgat ttgaccggaa atgtgggcat agaaaaaacg ccagctcaca
    26761 tgagaatgac gtttttcaga ggcttatttt gccaatcctt cagcaatctt gtcaaggttg
    26821 tatttcatca tgctgtagta gctgtcgcct tctttacctt gttctgcgat agagtcagta
    26881 aagatttgtg cgtagattgg gatgtttgtg tcttgagaaa cagttttcat tggacggtca
    26941 tccacacttg attctacaaa gagtgatgga acttttgttt ggcgaagttt ttcaaccaag
    27001 gtcttgattt gttcaggagt tccttcttct tcagtattga tttcccagat gtaggcactt
    27061 gggacaccat aggctttaga gaagtatttg aatgctcctt cgctggttac aatgagtttc
    27121 ttttcagcag ggatcttatt aaatttatcc ttactttctt tatcaagttt gtctaactta
    27181 tcagtatatt ctttgagatt tttttcatag aattctttat tgttagggtc tttggcgctc
    27241 aattgtttgg cgatattttt agcaaaaata ataccgtttt caaggttaag ccaagcgtgt
    27301 gggtcttctt ttcctttttc attttgacct tcaaggtaga taacatcaac gccgtcgctg
    27361 actgcgaagt agtctttgtt ttcagttttc ttggcatttt ctaccaattt tgtaaaccaa
    27421 gcattgccac ctgtttcaag gttgataccg ttatagaaaa tcaaatcagc ctcagaagtt
    27481 ttcttaacgt cttcaggaag tggttcgtat tcgtgtgggt cttgcccaat cggaacgata
    27541 ctatgaaggt caattttgtc accagcaata tttttagtaa tatcagcgat gattgagttt
    27601 gtagcaacaa cttttagttt ttgaccagaa gttgtatctt tttttccgct agcacatgct
    27661 acaagaatga ttgcagaaag aaagagaacg agtaatgtac ctaatttttt cattagatcc
    27721 tccaatttat tagggctttg ccccttattt taacaaatgt ttatttttca gtttcaaata
    27781 tcgttgtttg ggagcgataa agaagctaat gagaaagaaa ctagcagctg taagcacgat
    27841 actagaacct gccgcaacat taaaactata gccaataaag agtcccaaaa ctgaagcagt
    27901 agctccgaag gttgaggaaa ggaaaatcat acttttcaga ctattagcat acagataagc
    27961 agttgcagct ggggtaatca gcatggctac aatcaggata gttccgacac tttgcatggc
    28021 tgtcacagac acgagagtca ggagtaccat gagaaggtag tgatagaaat tgacaggcat
    28081 tcccatggct ttagccaaga gttcatcaaa ggaagttatc aagagttgct tgaagaaaat
    28141 ccagattaac aagaggatgg ctgcccccac acccatagta ataaacatat ccgtatcttg
    28201 gacggccaga atattaccaa aaaggatatg gaaaaggtca gttgaacttt tagcgacacc
    28261 aatcaatatg ataccgaggg ctaagaaaga agaaaaggta atgccgatgg cggtatcgct
    28321 tttgataatc gagtttcctt tgatgtaggt aatgatgatg gcagctagca atccaaagac
    28381 aatggctccg ataaagaagt caaggcccaa gatgaaggag agggctacac ctggtaagac
    28441 agcatgtgaa atggcatctc ccatgagtga catcccgcgt agaataatga aacaccccac
    28501 ggctccagct acaatcccga cgacaatagc tgttatcaag gcattttgta ggaaatggaa
    28561 tttttgcaat ccatcgataa attctgcaat cataggtcac ctccattgaa aaagagttga
    28621 ttaccgtaag cttcttttag attggtttcg gtaaaagttt cttttgttgg accaaaggca
    28681 atcacttctc gattgacaag taagacttga tcgaagtagt ggggaatctt gctgaggtcg
    28741 tggtgaacga tgagaaccgt cttcccagct tttttcaaat ctctcagcgt attcatgatg
    28801 atttcctcac tgacagagtc aatcccagca aagggttcat ccaagaggat atagtcggct
    28861 tcctgcacca aacatctggc aatcaagacc cgctggaatt gacctccaga cagttgacta
    28921 atttgacgtt cagcgtagtc agctaggccg acgatttcaa gggcctcttg cactttcttc
    28981 caatgtttag tctttaaact tcgaaagaga ggaatagagg gaaatagtcc taacgagacg
    29041 cattccttga ccttgatggg aaagttgtag tcgatattga ttttttgttc gacataggca
    29101 attcggtgta aggatttttt aacttccttg tcatcgagaa atgcctgacc ttgatgtggg
    29161 ataattccca gcataccttt taatagtgtt gatttcccag cgccgtttgg accaatgatg
    29221 ccggtaattg ttggtccatg gagcactagt gaaatatcct taagtgccaa cgtttctttg
    29281 taggagacac tgaggttttc gatacgtatc ataaacttgt attcctcctg tctcttaata
    29341 tacattaaaa aaaaaattaa gtcaagttaa tttttgaaaa aattaaaata ataactgaaa
    29401 aatagattct aaaaataact ttcaggataa atttctaaat tataaaacgc atagtatcaa
    29461 gtgtaaaaaa cttggaatta tgcgttttat catggaaaga ttttttataa tagctaaaaa
    29521 ataatagtta aatggttgtt aattgcattc cctagtgatt tttgttaaga taaaggcaaa
    29581 tacaaatgaa agcgagaaca agatgacacg ttatcaagat gatttttatg atgctatcaa
    29641 tggagaatgg caacagacag ctgaaatccc agcagataag tctcaaacag gaggttttgt
    29701 tgatttagac caggaaattg aagacctgat gctggcgaca acagacaagt ggttagcagg
    29761 tgaagaagtg cctgaggatg ctatcttgga aaactttgtc aaataccacc gcctagttcg
    29821 tgattttgac aagagagaag ctgacggtat cacacctgtc ttaccactcc ttaaagaatt
    29881 ccaagaattg gagacttttg cggattttac agctaaacta gcagagtttg agcttgcagg
    29941 aaaaccaaac ttccttcctt ttggtgtatc gccagacttt atggatgcta gaatcaatgt
    30001 tctatgggct agcgctccaa gcacaatctt gccagatacg acctactatg cagaagaaca
    30061 tcctcagcgc gaagagctct tgactctttg gaaagaaagc agcgcaaatc tcctcaaggc
    30121 ttatgatttc tctgatgaag aaattgaaga cttgctagaa aaaagacttg aattggaccg
    30181 ccgagttgcg gcagtggtgc tctctaatga agaaagttca gaatatgcta aactctatca
    30241 tccatattct tacgaagatt tcaagaaatt cgcgcctgcc ctacctttgg atgacttctt
    30301 caaagcagtt attgggcaat taccagacaa ggttattgta gacgaggaac gtttctggca
    30361 agcagcagag caattctaca gtgaggaagc ctggtctctc cttaaagcaa ccttgatttt
    30421 gagtgttgtc aatctttcaa ccagctattt aacagaagat atccgtgttt tgtctggtgc
    30481 ctacagccgt gccctttctg gagttccaga ggcaaaagat aaggtcaaag cagcttatca
    30541 tctagcacag gaacctttca agcaagccct ggggctttgg tacgcccgtg agaagttctc
    30601 tccagaagcc aaggcggatg tggagaaaaa agtggcaacc atgattgatg tctataagga
    30661 gcgtctgctt aagaatgact ggctcactcc agaaacctgt aaacaggcta tcgtgaagct
    30721 caatgtgatc aaaccttata ttggctatcc agaagaattg cctgcacgtt acaaggataa
    30781 ggtagtgaat gaaactgcca gtctttttga gaatgctcta gcctttgcgc gtgtggaaat
    30841 caagcacagt tggagtaagt ggaaccagcc tgtagactat aaggaatggg gcatgcctgc
    30901 tcatatggtc aatgcctact acaatcctca gaagaacctg attgtctttc cagcggccat
    30961 tttacaggcg cctttctatg acttgcatca gtcatcttct gctaactacg gtggtattgg
    31021 ggcagtgatt gcccatgaaa tttcccacgc ctttgatact aacggggctt cctttgacga
    31081 aaatggtagc ctcaaggatt ggtggacaga gagcgactat gctgccttca aggagaaaac
    31141 acaaaaagtc attgaccaat ttgatggaca ggattcttat ggagcaacca ttaacggtaa
    31201 attgactgta tcagaaaacg tggctgactt gggaggaatc gcagcagcgc ttgaagcagc
    31261 taagagagaa gcagacttct cagcagaaga gttcttctac aacttcggtc gcatctggcg
    31321 catgaaaggt cgtccagaat ttatgaaact tttggctagc gtcgatgtgc acgcaccagc
    31381 caaactccgt gtcaatgtgc aagtaccaaa cttcgacgat ttctttacaa cctatgatgt
    31441 caaagaagga gacggaatgt ggcgttcacc agaggagcgc gtgattattt ggtaatacaa
    31501 aaaatctagt catcagaaaa aggcatccaa tcacgtgtga aaaccttgat aggatgcctt
    31561 ttgtaataga aagatttgct ggatagttta cttaaatttc gattgtcatc atcttgctag
    31621 aaaaagggat tgaaggcctt ttcgtgagcg atagtagtag ctggaccatg tcctggatag
    31681 acatcgtagt ttggtagggt gaagagttgg gtctggatac tatgaaggag ttgctccatg
    31741 ctaccagtcg gaaggtcggt ccgtccgata gtttcgcgga atagagcatc tcccgtcaag
    31801 actaggtgag catcaggaaa gactagggaa acaccaccga tagagtgccc tggggtcggt
    31861 agaaccttaa aacgaaattc ctctagttgg tattcttcgt gaaagacaaa ggtgtgttct
    31921 gcaggttttg tgaccacatc tgccatatca tcgtggcgag ggagaccgga gagattatcg
    31981 acaggagtgt agagccagct ggcttcgctc tctgcgatat agacaggagg attgccaaac
    32041 gtctcgcgaa ccaagtccag actcatgata tggtcataat gggcgtgggt caagagaata
    32101 gcacagatcg gtttgttgat cttctcgatt gtctgacgaa tggcttccca atgactacca
    32161 ggatcgacga cgatgaggtg cttttcgcct tctagataat aggtattttc ataggcaaca
    32221 ggattcacgg ttttatggat tttcatacta gctccaatct caaagaatgt actaatactc
    32281 ttcgaaaatc tcttcaaacc gcgtcaactt tatctgcaac ctcaaagcag tgctttgaac
    32341 agcctgcggc tagctttcta gtttgctctt tgattttcat tgagtataaa ttaagtatag
    32401 cacagttagg gagaataggt aaggatttaa aatgaactta aaaaccagca tgactagatg
    32461 aagacaggct ggttatcaat ttatcaatat tggaaaggtg tcaattgccc ttcataggtt
    32521 gcataaactc cgtcattagc ttgtttgata gacgtgatgt ttagagtgct accgtagttg
    32581 gcttctcatt tgtcgctata ttcactataa gttatcctac tgggcaggtt ctggtcgtta
    32641 gcatagtatt gaacgagttt tttatagctt tgctggctga ataggaacag gcagcaaact
    32701 cctaacatta ggagagcaaa gatagaaata gcagtttttt tcataggtat tctccttata
    32761 aactaaagga tagaagaaag tatcttgagg atttttatac tcttcaaaaa tctcttcaaa
    32821 ccgcgtcaac gtcgccttgc cgtatatatg tgactgactt tgtcagtctt atctacaacc
    32881 tcaaagcagt gctttgagca acctgcggct agtttcctag tttgctcttt gattttcatt
    32941 gagtattaat tccaaaatcc agtcaaggta ccagtgtatg tgatacgagt tccaccgttt
    33001 atctttcgta tcttcaatgg aattggggaa atcagaaagt ctttgggtta caatatggtt
    33061 tccgttcttc tatctctcct tctatcacct aagtttaaaa tctaacttcg tagtatatta
    33121 tgggccaata attcagaatt atcaagcaat tttgaattat ttttttctta ttctgttcca
    33181 atctagtttt catattctta aaaaagtgat aaaatggtag gaagaattgg agagtagaga
    33241 tgccgaaaga agtgaattta acaggcgaag aagttgtcgc tttaaccaaa gaatatttaa
    33301 cggaagagga tgttcatttt gtccataagg ccttggtcta tgctgttgaa tgccacagtg
    33361 gtcaatatcg caaatcaggc gagccttata tcattcaccc tatccaagtg gcaggtattt
    33421 tagctaagct aaagctggat gctgtaacag tagcttgtgg attcttgcat gatgtggtgg
    33481 aagatacaga tgcgaccttg gacgatttgg aaagagagtt tggtcctgat gtgcgggtga
    33541 ttgttgacgg agttaccaag cttggcaagg tcgagtacaa atcgatcgag gagcaattag
    33601 cggaaaatca tcgcaagatg ctcatggcca tgtctgagga catccgcgtt attttggtca
    33661 aactgtctga ccgcttgcac aatatgcgga ccctgaaaca tcttcgaaaa gacaagcagg
    33721 agcgtatttc caaagaaacc atggaaatct atgccccact tgcccatcgt ttggggattt
    33781 ccagtgtcaa atgggaatta gaagacttgt ctttccgtta tctcaatcca acggagtttt
    33841 acaagattac ccatatgatg aaggaaaagc gcagggagcg tgaggccttg gtggatgagg
    33901 tagtcacaaa attagaggag tacacgacag aacgtcactt gaaagggaag atttatggtc
    33961 gtcccaagca tatttactca attttccgca aaatgcagga caagagaaaa cggtttgagg
    34021 aaatctatga tctgattgct attcgttgta ttttagatac ccaaagtgat gtttatgcca
    34081 tgcttggtta cgtgcatgaa ttttggaaac cgatgccagg tcgcttcaaa gactatattg
    34141 ccaaccgcaa ggccaatggt tatcagtcta tccatacgac tgtttatgga ccaaaagggc
    34201 cgattgaatt ccagattcga accaaggaaa tgcacgaggt ggctgagtac ggggttgcgg
    34261 ctcactgggc ttataagaaa ggtataaagg ggcaagttaa cagcaaggaa tcagctattg
    34321 gaatgaactg gatcaaggag atgatggagc tccaagacca ggctgatgat gctaaggaat
    34381 ttgtggactc tgttaaggaa aactatttgg ctgaggagat ttacgttttt accccagatg
    34441 gagctgtccg ttcccttccc aaagattcag gaccgattga ttttgcctac gaaatccata
    34501 ccaaggtcgg tgaaaaagca actggtgcca aggtcaatgg ccgcatggtt ccactgacaa
    34561 ccaagttaaa gacaggggat caggttgaaa ttatcgccaa cccgaactcc tttggaccta
    34621 gccgtgactg gctcaatatg gtcaagacta gcaaggcgcg caataagatt cgccagttct
    34681 ttaaaaacca agataaggaa ttgtctgtca acaagggtcg tgagatgctg atggctcagt
    34741 tccaagaaaa tggctatgtg gcaaataagt ttatggacaa gcgccacatg gatcaagttc
    34801 tgcaaaagac cagttacaag acagaagact ccctctttgc ggccattggt tttggggaaa
    34861 tcggtgcgat taccgtcttt aaccgtctga ctgaaaagga acgccgtgag gaagagcgtg
    34921 ccaaggccaa ggctgaggca gaggagcttg tcaaaggtgg cgaggtcaag gttgaaaata
    34981 aagaaactct caaggtcaag catgaggggg gagtggttat tgaaggtgct tctggtctcc
    35041 tagtgcggat tgctaagtgt tgtaaccccg tgcctggtga cgatattgtt ggctacatta
    35101 ccaagggtcg tggtgtggct attcaccgtg tggactgtat gaacctgcgt gcccaagaaa
    35161 actacgagca acgtctcctt gatgtggaat gggaagacca gtactctagc tcaaataagg
    35221 agtatatggc ccatatcgat atctacggtc tcaaccgtac aggactgttg aacgatgtac
    35281 tgcaagttct ttcaaataca accaagaata tttcaacggt caatgcccaa ccaaccaagg
    35341 atatgaagtt tgctaatatc catgtgtcct tcggtattgc caacctctct acactgacca
    35401 cggttgtcga taaaattaag agtgtgccag aagtttactc tgtcaaacgg accaacggct
    35461 agttgtccta gctcttacta gaaaggctat tatgaaaatc attatccaac gggttaaaaa
    35521 agcccaagtg agtatagaag gccagattca gggaaaaatc aatcagggac ttttattgct
    35581 agttggtgtt ggaccagagg accaagagga agatttggac tatgctgtga gaaaactggt
    35641 caatatgcgg attttttcag acgcagaagg caagatgaac ctgtctgtca aagatattga
    35701 aggagaaatc ctctctattt ctcagtttac cctctttgcg gatactaaga aaggcaatcg
    35761 tccagccttt acaggggcag ctaaacctga tatggcatca gacttctatg atgctttcaa
    35821 tcaaaaatta gcgcaagaag tgcccgttca gacaggtatc tttggagcag atatgcaggt
    35881 tgagctggtt aataacggac ctgttaccat tatcctagat actaaaaaga gataagaaag
    35941 accaagccca gtcggcttgg tctttctcat cgatcataaa atactccaaa aagaaatcgg
    36001 ttcttgatat gcttggggga agtctctttt caggctttgg cagatgcgat aggaagggat
    36061 gagatgtcct aggatgagga gagttccctg aaggaaaagt ggaatatcac ttaaagacac
    36121 caaggagaga atcatcaggc tatcccatag gagaatttgt aaagcaaaac gccagaatct
    36181 cggcctaatc tgggaataga gttgactaaa gtggtcacaa agttggtttg aaagataggt
    36241 caatagcaca ggatgaaaga aaatgagcca accactataa atcaaaatcc agtcccaagt
    36301 aagcccccct tttaaatgtc aaaaatgcca gcatgattcc atcaatgaca aggagttgaa
    36361 tggttttgat gaagatgatt tttttcatgc taaaacctcc ttttccttag agacactccc
    36421 ataaagagat gtgtttgtcg taaaagtctg gatagttttc tcttaggtag tcagctgtca
    36481 tataataaaa agtagaatgg caagcagtga taattgacat aagagatgaa aaacgctgag
    36541 aactaatgaa ggctaagaga acaaaaaata gaaaatcaat ggtgagaacc cctaaatagt
    36601 agaagcgaat ctttttattg atttgaggat aaatctcagc gaattgatgt ttgagtcgga
    36661 cgatcaagag aaatagcagg agtccttgag caaggaagaa aattaaacca gagagcaaga
    36721 gccactcaaa agatgtctcg agtctagtga taaaaaatgc aaatagtagc aaatcaataa
    36781 ctgcaattgc tataaaatgg attctataga gttttttcat gacaagacct tcctctttta
    36841 tctaacttca ttctactcca aaagaatggg agttacaact aaaatgataa aaatagcaga
    36901 agggagattc tcttaagttg gctagtattc tttatttgag tttccttcta tgtatctaac
    36961 ttcttcatca ttccagacaa ataaagctcc gattgcattg aggatataaa agatgtattt
    37021 accgatattg gcgaagtttc cttgaatacc agcttttgtc agctgaacga aattgtaaat
    37081 caaccaaaag ccccactgag ttgttagttt caatgcattc aaagcattgg caatgaggga
    37141 cagtgcaaag gcaatagttg ttacgtaggc aaggagatcc atcttgccct catatccgat
    37201 atagttggtc acaaaggcaa agaggaaggc gatgatggaa atgatgatgg ccgccaattt
    37261 tacctgtttt tggctcattt ggttgggtct gccttcttgc gaagattccc acttctttat
    37321 agcaaaggta taaatgagga aggtgacggg ataggtaatg atggccgcct tatttccaag
    37381 gatataatca atagcaccga acaaaagggt attaacaata ccaaagtaat ttccccattt
    37441 gcttaatttc cccgtgaaac gagtggacaa catggaaatc ccaacgttgg ttacggaaat
    37501 caatccaaag ggtacaagag ctgtccatga tccccagtct acaaatttat cgaggcgtga
    37561 gttgagataa ccagatgcaa tcgcaatccc aacgaccaaa gcaaccccga agaggtcaaa
    37621 tcatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta cctttctttt
    37681 tttcaaatat tctaccacca aatgaaagta aaataaaatg atagaaataa aaccctgaaa
    37741 ataaaacttt cagggttggt aggggacttg agaaattagt tgattttctc gacatagagt
    37801 tgttttgcaa tgtccatatt cacttgtaaa tcctcgtcgt tactgaggat agtgaaggta
    37861 ttgctgaagc catcaaactg cttgacttgg agctggtcac cgatgtgaag tgagtgcttg
    37921 tccagataat ggagaatgtc aaaattatcg tgcacccgag tcaggcggta ggcgccagct
    37981 tccttgatat cagctagtgg gaggttattg atttcaacga ggagttctcc cttggcagga
    38041 atagttcctc cgtgggggca ggttttaggg aaacctagca gtttatctag tctttccacg
    38101 aacaggtcag agacagtgtg ttccaagacc tcagcttcct cgtgaatctg gtcacttgta
    38161 tagtctaaat gatgaactag aaaaacttca atcaagcggt gcttacgata gagctcagag
    38221 actagtttga gaccgaggtc agtcagtaga tagccacatt ccttgtcctt taggatgagg
    38281 ttttcacttt tcattcgttt gatcatttca gttacggcag ggggagagac ttgcatgcga
    38341 gccgcaattt ccttgttggt aatcttatgc aggtctatgc caatttcata aatacatttt
    38401 agatagtctt ctttgtttgg ggtcattcgt ttcctcttgt ctaatatctt tatctagtat
    38461 atcaaaaaaa gctagatttc tctagctgtg actttttatg ttatacttat tgcaagagaa
    38521 aaaacgagga gatggatatg acgaaaatag ctcttctttc agatattcat ggaaatacca
    38581 ccgccttgga ggctgttttg gcagatgctc ggcagatagg agtggatgaa tactggcttt
    38641 tgggagatat tctcatgcca gggacaggac gtagaaggat tttggacttg ttggatcaac
    38701 taccgattac ggctagagtt ttgggaaact gggaagacag tctttggcat ggtgtccgta
    38761 aggaattgga cagtactcgc cccagtcaac gctatctctt gcgccagtgc cagtatgttt
    38821 tagaggaaat ttccctagaa gaaattgaag tgctccacaa tcaacctctt caaattcatc
    38881 gtcagtttgg ggatttgacg gtgggaatta gccatcatct gcctgataag aactgggggc
    38941 gagagttgat tcatactggc aaacaagagg agtttgaccg cttggtgact catcctccct
    39001 gtgatattgc tgtttatgga catattcacc agcagttgct tcgttacggg actggtgggc
    39061 aattgattgt caatccgggt tcgattggcc aacctttctt tttggacgct cagctacgga
    39121 aggacttgcg ggcccagtat atgattttgg agtttgatga caaaggcctg gtagatatgg
    39181 acttccgacg ggtagactac gatgtggcag cggaattgca gctggctaaa gacctgagac
    39241 ttccctattt tgaggtttac tatgaaagtc tggtcaatgg gatccaccat actcatcatc
    39301 aggaattttt gagagaattg gctcagaaag agggctgcga tcgggagtta gacgactggt
    39361 tgaaaagtgg taacgattga cattacaact aaaaagggta taataataga aaaagaagag
    39421 tagaggcagg gtagcctcgt aaaaaggaga agaggatgca aattccaagt agatttacca
    39481 ttgcgactca tatgctgata atcattgccc tcgaggggaa ggaaagcaag gtgaccagtg
    39541 attttctggc tgctagtgtc ggggtcaatc ctgtcattat cagaaagatc ttgtcccagt
    39601 tgaagaaggc agagctgatt tcagtagcgc gtggaacggg cggaacagag attgtcaagg
    39661 accttaagga tattagtctt ttagatgttt atcaggcggt cgaatgtctt ggtaagacag
    39721 gtcaactctt cagtttccat gacaatccga atccaaattg ccctgtagga gctcatattc
    39781 atgatgtttt ggatcaaaaa ttggagagaa ttcagttgac tatggaggca gaacttggtc
    39841 agaccagtct agaaaaagtc gtggccgatg cagagagtca gatgaaggat taagagggat
    39901 aaatgccctc tttttttctt tggataatta tgataaaatg tagctattaa aggagtaaga
    39961 aatgtatctc gttataggaa ttgtattagc ctttatagtg tcattttgga aggataatag
    40021 aagtttgtgg aatccagtat tatttttatt atccctcatt tcaagttgtt tttatctatc
    40081 ctaccttttt tataaaaatg gatacgagaa tgttcagtta gctttttatg tatttgcctt
    40141 tgtcttactt ccttttttgc tttttctaag tggcatcttt ttaatctata atggggttat
    40201 tttgttgaag cgagagggac gttccaagcc ccattatctc tcaatgctct ttgattttta
    40261 ttgactatta gattctattt aaaaagactt agaatgcaca tgaaagtatg tattctaggt
    40321 cttttgtttt gtatacattt aattttcaag agtattatct atttttccat acctggtaac
    40381 gagtatcaat caataactgg gtaaggcgac ccaaggtttc tttttcttct ggagtgaggg
    40441 attgagcttg gacaaagaga tgatgaatgt attcaagcgc ctttaaggaa gccaagtcat
    40501 tgatagagct aataccagca tcaagaatag tgccaaagaa gaggtcgaag tagagctgaa
    40561 gttcttcgtc agggactgtg gtcacccatt ctttaaaggt tgtgtctact tgccggctat
    40621 cactgttggt cttatccagt tgaacgaagt gcttgtcctc aatctgccaa ctaaaggtat
    40681 cgtgctgggc gatgccaccc agggcagtac tctgaacgat gatttggtga gcaggaattt
    40741 ccagcatcat accgataatg gaaccttgtg gaatgaatat cttgcttcta tccattatcc
    40801 tttgataacc cgcagtctgt gtcaattctt gatggagacc aggtgcatca aatgtataaa
    40861 ctgctgtgat ctgattttgc aaactttgct caatttggct agcagcatag atagcgagat
    40921 ttcctccctt ggaatgccca gccagaataa ccttttgctt aggatgatgg gcaaaaaagt
    40981 tctttaaata gcgaagggcg tgcttttgag caggaatttc cttcatatag gtcaggtgga
    41041 aatcttcctt ccagccaatg atactgtcat ctgtcccacg aaagacaatc agataggtat
    41101 cgaggctgac acgataagtc atagccgcaa attgcttttg cagttcaggg tcgatgtcgt
    41161 tgataaaatg ggagagtttg caatttttga agcgcttgtg ttgagccaat tcatctaata
    41221 attgaaggcg atttttgcta gtaagcatgg tgggctctct tggaacctga ggtgctagat
    41281 ctaaaagacg ttgaggaagt gtggagacca gattatcaaa ggagaggtag gtgatttcta
    41341 ttaaggttag aatgtctaac tcattcaagg gaaggtcgta ataagaatca tatgcgacat
    41401 ctttcagata gtcaaaaata ttggccataa gagctccttt ctttttattt atcttagcaa
    41461 atttccctca aattagctag tagcattgcc tgtttgtact ggctaaaaac aggctatttc
    41521 aaattcagtt tcagaccatc tggcatggaa aaatctgtta taataatgga aaaggagaag
    41581 cgcatgcaca agattttatt agtggaagat gatcaggtca ttcgtcaaca ggtcgggaaa
    41641 atgctctctg aatggggatt tgaagtggtc ctggtagaag actttatgga agttttgagt
    41701 ctatttgttc agtcggaacc tcatctggtc ctcatggata ttggtttgcc cttgtttaat
    41761 ggttatcact ggtgtcagga aatccgcaag atttccaagg tacctatcat gtttctttct
    41821 tcgagagacc aggctatgga tattgtcatg gcaatcaata tgggggcgga tgactttgtg
    41881 accaagcctt ttgaccagca ggttctttta gccaaggttc agggcttgtt gcgtcgttcc
    41941 tatgagtttg ggcgtgatga gagtttgctg gaatatgctg gtgttatcct caataccaaa
    42001 tccatggatt tacattatca agggcaagtt ttgaatttga ccaagaatga attccagatt
    42061 ttacgcgtgt tatttgagca tgcaggcaac atcgtagcac gtgacgacct gatgcgggaa
    42121 ctttggaaca gtgacttttt cattgatgat aataccctct ctgtcaatgt ggctcgtttg
    42181 cgtaaaaagt tggaggagca gggattggta ggatttatcg agaccaagaa aggaataggg
    42241 tacggattga agcatgcttg attggaaaca attttttcta gcctatctgc gctcccgtag
    42301 tcgtcttttt gtctatctgc tttctttggc atttctggtc ttactctttc agtttttatt
    42361 tgccagtcta ggaatttact tcctctactt tttcctcttg tgttgctttg taaccatctt
    42421 atttttcact tgggacatat tggtggaaat gcaggtctat cgccaggaac ttctctatgg
    42481 agagagggaa gccaagtctc ctttggaaat agctttagca gaaaaattag aagcgcgtga
    42541 gatggaactc tatcagcaga ggtcaaaagc agaaagaaaa ctgacggatt tgctggatta
    42601 ctataccttg tgggtccatc agataaagac ccccattgca gccagtcaac tcttagttgc
    42661 agaagtggtc gaccgccaac tgaagcagca gctagaacag gaaattttca aaatcgactc
    42721 ctataccaac ctagttttac agtacctgcg tttagaaagt ttccatgatg atttggtctt
    42781 aaagcaggtt caaattgagg acttggtcaa ggaaataatt cgtaaatatg ctcttttctt
    42841 tattcaaaaa ggcttaaatg tcaatctaca tgaccttgat aaagaaatcg tgacggataa
    42901 aaagtggctg ctagtggtta ttgagcaaat catctcaaac agtctcaagt acaccaagga
    42961 aggtggtctg gagatttata tggatgacca agagctttgt atcaaagata cgggaatcgg
    43021 gataaaaaac agtgatgttc tccgagtatt tgaacgtggc ttttcaggat acaatggccg
    43081 tttgacccag cagtcctctg gacttggcct ttatctatct aagaaaattt ctgaagaact
    43141 ggggcatcag attcgtatcg agtctgaggt cgggaaagga acgacagtgc ggattcagtt
    43201 tgctcaagtg aacttagtcc ttgagtaaaa atagatgaga aaaagcctcc agattggagg
    43261 cttttatgct agactcttat ttctcaacgc gtgatttgtt ggcgatatca gctaggatag
    43321 cttgaacaaa attatcaact gagacagttt gtgtttcttt ttggccgtag cgacgaacgt
    43381 tgactgtttc gtcttccatt tctttgtctc caacaattaa ttggtaagga atcttgctgg
    43441 tttgtgaagc acggatcttg aactgcattt tttcattgcg ctcatctacg tctgcacgga
    43501 caccgcggtc acggagtttc ttggccactt cccaagcgta gtccacgtgt ttttcgttag
    43561 atactgggat gagggttact tggtgtggtg ccagccatgt tgggaaggcc cccttgtagt
    43621 tctcaatcaa gatagctgtg aagcgttcca tagttgagat aaccccacgg tggatcatga
    43681 ctggacggtg atcttcgcca tcagctccga tgtatttgag gtcgaagcgt tctggcaaca
    43741 agaaatcaag ttggatagta gaaagggttt cttcttttcc aagggcagtt ttaatctgga
    43801 tatccaattt tggtccgtag aaggctgctt caccttcggc ttcaaagtag tccacgccca
    43861 tttcatcaag agctgcacga agcatggttt gggcattttc ccacatctca tcgttatcaa
    43921 agtacttatg agtatcttga gggtcacgaa gagagaggcg gaagcggtag tcagtcaagt
    43981 tgaagtcttc ataaacatcg ataatcaact gaagggcacg ttggaattct tcttggattt
    44041 gttctggagt aacgaatagg tgaccgtcgt tgagtgacat ttcacgtaca cgttgaaggc
    44101 cagtgagggc accagatttt tcgtaacggt gcatcatacc gatttcagcg atacggattg
    44161 gcaattcacg gtaagagtga acatggtgtt tgaaaacttg gatgtggtgc ggacagttca
    44221 ttggacgaag gacaaattct tccccgtcac ccatgtccat ggttgggaac atgtcttctt
    44281 ggtaatgatc ccagtgacca gaagtcttgt aaagctcaac agaagcaagt ggtggagtgt
    44341 agacgtgttg gtagccagaa gccaactctt tgtttacgat gtagcgttcc aattcacgac
    44401 ggatagtcgc accatttggc aaccagaatg gcaaaccttg tcccacttct tgtgaaatca
    44461 taaagaggtc aagctcttta ccaagtttac ggtggtcacg ttccttagct tcttcacgca
    44521 tttgaaggta gtttttcaag tctttcttgt caaaccaagc tgtaccgtag atacgttgca
    44581 tcatagcgtt gtcgctgttt ccacgccagt acgcaccagc tacatggaga aggtggaaga
    44641 tttggatacg acctgttgat ggaacgtgag gtccacggca gaggtctaca tattcaccct
    44701 gacgatagat agtcaaaccg ccttcgtctt ctgagtgttc ttcaatcaat tccaacttgt
    44761 aagggtcatt tttgaagatt tcacgtgcct cgtctttagt cacttcttca cgaatagatg
    44821 ggaagttttc tttgacgatt ttttgcattt cgtcttcgat atgaggaagg tcttcgttag
    44881 agatttgacc agctgtgttg tcagtatcgt agtagaaacc atcttcgatg gctggaccaa
    44941 ctcccaagtg aatgtctggg aaaagacgac gagctgcttg ggcgaacaag tgagctgctg
    45001 agtgacgcaa gattggaagg gcatcttcgt gatcaggtgt cacaatttcg atgcttccat
    45061 cttcagtgat agcgcgagta gtgtcgatga gtttgccgtt gaatttacca gccaaggctt
    45121 ttttagctag ggaattgctg atagattggg caatttcaaa agttgttacg ccagattcga
    45181 attcacgaat agcgccatct gggaaagtaa tgttaatcat gatgttctcc ttttttatta
    45241 tttcatagtt tctaagcatt gattttttat cagcagacta cttccaagtc ctaacgttca
    45301 attgcttttc tttatcagag aggaagtttt ccatttccgt cagaatatct atatccaaac
    45361 gttgagaaag ttctaatagt caccagatat tttctgaaag tttttgttcc agtgtgtagg
    45421 gtgtttcatc atagtagcgt ccttgttttg tcatcaccag tcgttggaaa tttccaatat
    45481 cattagataa agccaagagg tcttcttcta ccgtccactt ggaatcatga tgcttaactt
    45541 ccagttcgtg ataagcttgt cggattgccc aactgcgctc cactaattct tgcaactcca
    45601 taattagtat cctaataaaa aaatgcgaca tcctcgaaag gacgtcgcaa cgtggttcca
    45661 ccttcattta tgtacctcaa aagagaggga cacctctgat tggctctaac gtggccaccg
    45721 ttttatgttt tcataaaaaa ctcaagagta gtatcagttt agacttccta tgcgtttcca
    45781 gcaaccacgc actctctagt agaaagggac taagtgactt gtctctatgg attattatag
    45841 catgattgtg agatttttca aggattttgt gaaagttttt tgtttttcat tttttgtaga
    45901 atatgcttga tgctaatacc agaatccatg cccaccagag caactgtttc atagattagc
    45961 aagtaaatta gtataaactc accaaaggtt atgatagtaa agtaaaagag cagtccgtta
    46021 ccaactaacc atcaaagtga gaaacggaaa cggtagctat agagtaacga tacaatcaag
    46081 attaccagag gtgtaaagaa gagaagattg tttatatagt gtaagggggt cagaaacaac
    46141 tagcaagaac aactcataaa gtggccaata aaagaataat atgaccagat agtaggggag
    46201 atgggaatag aatctacgca tgataatcac ctcgttttaa aaaaacagac aacttagatc
    46261 tcttgctatg attattatag catgtttaaa acaagaaagt aaatttgttg acaaagaaga
    46321 tttttctttt cactagaatc atggttagtt ttcttggtag aaatattttg ataataatta
    46381 agcaagacta ttgacattga ttattaagag tgtcacaatt gctgtaacta aaataattac
    46441 aacaagagag gtataaaaaa tgaaactagc agttattgca gcaaatggac aagcggggaa
    46501 agcaattgtt gaagaagtag tcaaacgagg acatgaagta acggctattg ttcgttctga
    46561 aaacaaaagt caatctgagt ctattattaa aaaagattta tttgagttga caaaagatga
    46621 tcttactgga tttgatgctg ttatttcagc gtttggtgct tatacaccag atacgctacc
    46681 gctccacagc aaatcaatcg aactatttaa tcagcttctt gctggaacac agacacgttt
    46741 tctagttata gggggagcag gaagccttta tatagatgaa acaaaaatga cacgactttt
    46801 agatacgcct gattttcctg aagaatttaa gccactagca aaagctcaag cggatgaatt
    46861 ggatcttctt cgtacaaaaa ataatctcaa ctggactttt gtcagtcctg ctgtagattt
    46921 tattcccgat ggtgaaaaaa caggaaacta aattctagca ggagaaattt ttactactaa
    46981 tggaaaagga ataagccaga ttagttatgc agattatgct attggattgg tagatgaact
    47041 tgaaaaaggt catcatataa aagaacgtat ctctttactt gaaaaataat aactatgaga
    47101 gtattaatgt ttgacagaaa atttaaatct tggtaaaata gggattgtcg taaagacaaa
    47161 taacttcttc ttggttacag gcatgccaac ctgtcactcg gatgaagcca aataaaaagg
    47221 agaaacatca tggcaatctc aaaagagaaa aaaaatgaaa tcattgcaca atatgcacgt
    47281 cacgaaggtg atacaggttc agtagaggtt caagttgctg tccttacttg ggaaatcaat
    47341 caccttaacg aacacatcaa acaacataaa aaagaccacg ctacttaccg tggattgatg
    47401 aaaaaaatcg gtcgccgtcg taacttgctt gcatacttgc gtaaaaacga cgttaaccgt
    47461 taccgtgagt tgatcaactc tctaggactt cgtcgctaat tcaagataca aaggccgtca
    47521 aaagcacaaa gcaaaaatag gaaaattgac gaagaaactt cagtttctag gagattttat
    47581 cttttttgcc aagtgcttag gccgtgttca attgagcata tcttgataat aaagctactc
    47641 taaattgggt agctttattg cgttgtcacc ttacctcgct atactcaagt ataatcttcg
    47701 gttacggttc ctagcactgt aaggtaaaat aaactagctt ttctcccttc ggggagattt
    47761 ttttgtttca ctgaaagttt cgtacgatct tcgcctcgtc ccctagtcta taaacgattt
    47821 atctagcaag aatcatgatg ctaagggcgt caaaaatccg tatgaaaata gggaaatgac
    47881 acagtgttcg atgagcacaa ggagtttcat ctttttcact aggattttag cccgggctaa
    47941 aatcagctct ctgacttcag agggtttttt attgaggttt tatcggtaac aattttggag
    48001 actacaaaaa cctcaaatgg tatcagctaa ttacaccata aaggtgcgca gctactcggc
    48061 ttgaaaagcc gagtagctgt ctgcaagccc cctcggagag cccacacttt acgaagtaaa
    48121 gtatagtatg ttatacttta catggaagta gtcaccgaat tccagttaga aattactttg
    48181 taactacgtt ttgaggagga gtaaaatgct ttcctatgtt cgacattacc cactagcgat
    48241 agctaaatta atgtgtttgt gctctcctaa aatctgctga tttattactg actaatacag
    48301 gaggtttttt ttatgggaca gacaatcata tctgctattg gtgtttatat ttccaccagt
    48361 atcgattatt taattatttt aattatttta tttgcacagc tatcacagaa taaacagaaa
    48421 tggcatattt atgcggggca atatctaggc acaggcttac ttgtaggggc gagtttagtt
    48481 gctgcttatg tcgttaattt cgtgcctgaa gaatggatgg ttggattgct tggtttaatc
    48541 cctatctatt tagggattcg ctttgcaatt gttggagaag atgcggaaga agaagaggaa
    48601 gaaattattg aaagattaga acaaagcaag gcaaatcaac tgttttggac agttacattg
    48661 ctgacaattg cgtctggcgg agataattta ggtatctata taccttattt tgcttcgtta
    48721 gattggtcac agaccctcgt ggccttgctt gtgtttgtaa tcggcataat tatcttttgc
    48781 gagattagtc gggtgttatc ctctattccg ttaatattcg agacaattga aaaatacgag
    48841 cgaatcattg tgcccttagt attcattcta cttggactat acatcatgta tgaaaatggc
    48901 acgatagaga cttttctgat cgtgtagatt tttttgtttc actaggattt tagcccgagc
    48961 tcaaatcagc tctctgattt tcagagggct ttttcattga gtataaatgg acaatcttaa
    49021 agttactcta ttgtagagtg gcttttgatt tgattaggag attcttataa atatagcaaa
    49081 atgaaacaaa aacaggacaa atcgatcagg acagtcaaat cgatttctaa aaatgtttta
    49141 agaagtagag gtgtactatt ctagtttcaa tttgctatat aaatgaaaac cttagctgtt
    49201 tggccaaggt tcatttcttc tatgcaagtt cttctctttt cttatctggg ttccagatga
    49261 agcttgcgat aaagctaaag atgatggtta ggatagcgag gataatagca aggatgaggg
    49321 cagggatgcg gataaaccac cagagtggat ttggtttttt atcattgtgc cattgtttcg
    49381 tttcttcgtc cagacgttgg aattctgttt gaatacgatt ggcgactgtt tcaatgcctt
    49441 catcattcat tttcttgata tctgagatat cgattggatt tccaaagttc atatcgacac
    49501 gttcacggct aatcaagccc ttcaaagtca tgggaccggt gtaggtaacc ggcatgatac
    49561 ggaccttggc cattttggca atcagtgctg cgcccccctt gacatcgttt gagtggcggc
    49621 taccacttgg aaacatgatg agagagcggt cacttttttt gagaacgttg ataggatatt
    49681 tgatggctga ggcgctggga ttttcacggt cgatgggaaa ggcgccacac atacgaatcc
    49741 accaaccaaa gatacggttg gtaaagagtt ctttttttgc cataaagatg aactgttttg
    49801 gcttggtcgc aaaggccata taaacaggat cccaccaggt acggtgaggc gcaactaaaa
    49861 tataattttc atcttgatta ggaattttat cagtattatg atagtgagca ttgccattga
    49921 tggaccataa gagcaataca actaatccac gcaaataagt ataaaacatg cgatctcctt
    49981 cgattgtttt cttgttatta ttatacctta tcaaaggagg gctggcaaac ttttcccttg
    50041 actagatgca tatttgggat gaaattagaa ttctgttaaa aaaaatgata taatagaatt
    50101 tatggataaa aataagatta tgggattaac ccaaagagaa gtcaaggaaa gacaggctga
    50161 gggtttggtc aatgacttta ccgcatcagc cagtaccagc acttggcaaa tcgttaaacg
    50221 aaatgtcttt acccttttta acgctttgaa ctttgccatt gctttggccc ttgcctttgt
    50281 gcaggcttgg agcaatctgg tcttctttgc tgttatctgc tttaacgctt tttctgggat
    50341 tgtgaccgag ctacgagcca aacacatggt ggacaagctc aatctcatga ccaaggaaaa
    50401 ggtcaaaacc atccgtgatg gtcaggaagt tgctcttaat cctgaagaat tagtgctagg
    50461 agatgtcatt cgtttgtctg caggagagca gattcctagt gatgccttgg ttttggaagg
    50521 ctttgcggaa gtcaatgaag ccatgttaac gggagaaagt gatttggtgc aaaaggaagt
    50581 tgacggctta cttttgtcag gaagtttcct agccagtggg tcagttttat ctcaagttca
    50641 ccatgtcggt gcagacaact atgctgtcaa actcatgctt gaggctaaga ccgttaaacc
    50701 catcaactcc cgtatcatga aatcgctgga caagttggct ggttttactg ggaagattat
    50761 cattcccttt ggtctggctc tcttgctgga agccttgctt ttaaaaggcc tgcctctcaa
    50821 gtcatctgtt gtaaactcgt cgacagctct tttgggaatg ttgcctaagg gaattgccct
    50881 tttgaccatt acttcgctct tgactgcagt tatcaagcta ggtttgaaaa aggtcttggt
    50941 gcaggagatg tactctgttg agaccttggc gcgcgtggat atgctctgtc tggacaagac
    51001 gggtaccatc acccaaggaa agatgcaggt ggaggctgtt cttccgttga cggaaacgta
    51061 tggtgaagag gctattgcca gcatcttgac tagctacatg gcccatagtg aggataagaa
    51121 tccaactgcc caagccattc gccagcgttt tgtgggagat gttgcttatc ctatgatttc
    51181 caatcttccc ttctcgagcg atcgcaagtg gggagccatg gagttagaag gtttgggaat
    51241 agttttctta ggggcacctg agatgttgct ggattctgag gtcccagaag ccagagaggc
    51301 cttggagaga ggttcacgtg tcttggtctt agctctcagt caggagaaat tagaccatca
    51361 caaaccacag aaaccatctg atattcaggc tctagccttg ctggaaatct tggatcctat
    51421 tcgagaggga gcggcagaga cgctgaacta tctccgttct caggaagtgg ggctcaagat
    51481 tatctctggt gacaatccag ttacggtatc cagcattgcc cagaaggctg gttttgcgga
    51541 ctatcacagc tatgtcgatt gttcaaaaat cacggatgag gaattgattg ctctggcgga
    51601 ggagacagcg attttcggac gtgtttcccc tcatcaaaag aaactcatta tccaaacgct
    51661 gaaaaaagcg ggtcatacaa cagctatgac tggggatgga gttaatgata tcctggctct
    51721 tcgtgaggcg gattgttcta tcgtaatggc ggagggagac ccggcaaccc gtcagattgc
    51781 caacctggtt ctcttgaact cagactttaa tgatgttcct gagattctct tcgagggtcg
    51841 tcgcgtggtc aataacattg cccacatcgc cccgattttc ttgataaaga ccatctattc
    51901 cttcctgtta gcagtcatct gtattgccag tgctttacta ggtcggtctg aatggatctt
    51961 gattttcccc ttcattccaa tccagattac catgattgac cagtttgtgg aaggtttccc
    52021 accattcgtt ctgacttttg agcgaaatat caaacctgtt gagcagaatt tcctcagaaa
    52081 atccatgctt cgtgccctac caagcgctct catggtcgtc tttagcgtcc tgtttgtgaa
    52141 aatatttggg agtagccaag gttggtctga gttagaaatc tcaactctcc tctattatct
    52201 cttggggtca attggtttct tatccgtatt tagagcctgc atgccattta ccctatggcg
    52261 tgtcctcttg attgtttggt cagtaggagg tttcctagcc acagctctct tcccaagaat
    52321 ccaaaaactg cttgaaattt caaccttaac aggacaaaca ttacctgttt atggtgtcat
    52381 gatgttggtc tttaccgtga ttttcatcct gaccagtcgc tatcaagcca gaaaataaag
    52441 aaaggctgca atctgtggat tgcagtcttt ttaggtacaa gattgccagc cgaaatgtgg
    52501 tataataaga ggtaatagag tttggaaagt gagagaagat gatttcaaag agattagaat
    52561 tggtagcttc ctttgtgtca cagggggcta ttttactaga tgtgggaagt gaccatgctt
    52621 atctgcctat cgagttggtt gagagaggcc aagtcaaaag tgctattgca ggtgaggtgg
    52681 tggaaggtcc ctatcagtct gcggttaaaa atgttgaggc tcacggccta aaggagaaaa
    52741 tccaagtccg tttagccaat ggcttggcag cttttgaaga gactgaccaa gtgtctgtca
    52801 ttaccatcgc agggatgggc ggccgtttga ttgctaggat tttagaagaa ggcttggaca
    52861 agttagctaa cgtagagcgt ttgattctcc agcccaataa tcgtgaagac gacttgcgta
    52921 tctggctaca ggatcatgga ttccagattg tagcagaaag catcttagaa gaagctggaa
    52981 agttttatga gattttggtg gtggaagcag gacaaatgaa gctatcagcc agtgatgttc
    53041 gctttggtcc cttcttgtcc aaagaagtca gtccagtatt tgtccaaaaa tggcaaaaag
    53101 aagctgagaa gctagagttt gccctcggac aaatcccaga aaaaaatctg gaggaacgtc
    53161 aagttctagt agataagatt caagctatca aggaggtgct ccatgttagc aagtgaagtg
    53221 atccaagctt atgaagcctt ttgccctcag gaattttcta tggagggaga cagccgtggt
    53281 ttgcaaattg gcactttaga caagggtatc caaagggtca tggttgccct cgatattcgt
    53341 gaagagacgg tggcagaggc cattgaaaag ggtgtggact tgattatcgt caagcacgcg
    53401 cctatctttc gtcctatcaa ggacttgctt gccagccgtc cgcaaaatca gatttacatc
    53461 gacctgatta agcatgacat cgcagtttat gtcagccata ccaatattga tatcgttgaa
    53521 aatgggctca atgactggtt ttgtcagatg ctaggaatcg aggagacgac ttatctgcag
    53581 gaaacaggtc cagaacgtgg aattggacgt attgggaata ttcagcctca gacattttgg
    53641 gaattggccc aacaggtcaa gcaagtcttt gacctagata gccttcgaat ggtgcattat
    53701 caagagaatg atttgcagaa gcctatttca agagtagcaa tttgtggtgg aagcgggcag
    53761 tctttctata aggatgcttt ggcaaagggg gcagatgtct atatcactgg tgatatctac
    53821 taccatactg ctcaggatat gctgtctgat ggcttgttag cattggatcc aggtcactat
    53881 atcgaagtgc tttttgtgga aaaaatcgca gcactcctta ctcaatggaa agagaaaaaa
    53941 ggctgggaac tagagatttt acctagtcaa gcatcgacca atcctttccg tcatatctag
    54001 ttagaaagtg aagacaatga aaaaagttgc cattattgga gcaggaattg tgggagcaac
    54061 agctgcctac tacctctcga gagaaagtga cctagaggtg accgtttttg accatgagca
    54121 aggtcaagcc accaaggctg cagcaggaat tatcagtcct tggttttcca aacgccgtaa
    54181 taaagcctgg tacaagatgg cgcgcttggg ggctgatttt tatgtggatt tattagctga
    54241 tttagagaaa tcaggacaaa aaatcgactt ttaccagcgt tcgggagtct ttctcttgaa
    54301 aaaggatgaa tccaagttgg aagaacttta tcaactggcc ctccagcgca gagaagaatc
    54361 tcccttgata gggcaattag ccattctgga ccaagcctca gctaatgaat tattccctgg
    54421 tttgcaggga tttgaccgcc tgctctatgc ttctggtgga gcgagagtag atggccacct
    54481 cttagtgact cgtttgctgg aagccagtca ggtcaagctg gtcaaagaaa aagtgactct
    54541 gacaccgtta gcatcaggct accagattgg tgaagaggag tttgagcagg ttattttggc
    54601 gacgggagct tggttggggg acatgttaga acccttgggt tatgaagtag atgttcgtcc
    54661 tcaaaaagga caactacgag attatcagct ggtccaagac atggaagctt accctgttgt
    54721 catgccagaa ggggagtggg atttgattcc ttttgcaggt gggaaattgt ccttaggcgc
    54781 tacccacgaa aatgacatgg gatttgattt gacggtagat gaaaccttgc tccaacaaat
    54841 ggaggaggcc accttgactc actatctgat tttggctgaa gctacttcaa aatctgagcg
    54901 tgtgggaatc cgtgcctata ccagtgattt ctctcccttc tttgggcagg tgccagaatt
    54961 ggcaggtgtc tatgcagcca gtggactagg ttcatcaggc ctcacaactg gtcctatcat
    55021 tggttaccat ctagcccaac tgatccaaga caaggagttg accttggacc ctctaaatta
    55081 cccaattgaa aactatgtca aacgagtaaa aagcgaataa tactcaatga aaatcaaaga
    55141 acaaactagg taactagccg agggttactc aaagcactg
//
LOCUS       DAVHBD010000008        54525 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000008 DAVHBD010000000
VERSION     DAVHBD010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.008"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(1..142)
                     /locus_tag="VVK04_000487"
                     /pseudo
     CDS             complement(1..142)
                     /locus_tag="VVK04_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            128..613
                     /locus_tag="VVK04_000488"
     CDS             128..613
                     /locus_tag="VVK04_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU3989190.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTILGSTVDKDDALVSCLVAPGFEFEDFELFERADLLATYPEHKEMIEHLTR
                     Y"
     gene            697..1404
                     /locus_tag="VVK04_000489"
     CDS             697..1404
                     /locus_tag="VVK04_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3989191.1"
                     /translation="MTKQVLLVDDEEHILRLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1405..2736
                     /locus_tag="VVK04_000490"
     CDS             1405..2736
                     /locus_tag="VVK04_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU3989192.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2903..3778
                     /locus_tag="VVK04_000491"
     CDS             2903..3778
                     /locus_tag="VVK04_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEU3989193.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3896..4759
                     /gene="pstC"
                     /locus_tag="VVK04_000492"
     CDS             3896..4759
                     /gene="pstC"
                     /locus_tag="VVK04_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU3989194.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4752..5567
                     /gene="pstA"
                     /locus_tag="VVK04_000493"
     CDS             4752..5567
                     /gene="pstA"
                     /locus_tag="VVK04_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU3989195.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5569..6321
                     /gene="pstB"
                     /locus_tag="VVK04_000494"
     CDS             5569..6321
                     /gene="pstB"
                     /locus_tag="VVK04_000494"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU3989196.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6336..6986
                     /gene="phoU"
                     /locus_tag="VVK04_000495"
     CDS             6336..6986
                     /gene="phoU"
                     /locus_tag="VVK04_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU3989197.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7054..7479
                     /locus_tag="VVK04_000496"
     CDS             7054..7479
                     /locus_tag="VVK04_000496"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3989198.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(7653..8033)
                     /locus_tag="VVK04_000497"
     CDS             complement(7653..8033)
                     /locus_tag="VVK04_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU3989199.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            8245..9261
                     /locus_tag="VVK04_000498"
     CDS             8245..9261
                     /locus_tag="VVK04_000498"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU3989200.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9283..10182
                     /gene="galU"
                     /locus_tag="VVK04_000499"
     CDS             9283..10182
                     /gene="galU"
                     /locus_tag="VVK04_000499"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU3989201.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(10249..10926)
                     /locus_tag="VVK04_000500"
     CDS             complement(10249..10926)
                     /locus_tag="VVK04_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU3989202.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPEISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(10910..11449)
                     /locus_tag="VVK04_000501"
     CDS             complement(10910..11449)
                     /locus_tag="VVK04_000501"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU3989203.1"
                     /translation="MKSELRKQVLHEMKTLSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLELQ
                     GDLEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(11461..12591)
                     /locus_tag="VVK04_000502"
     CDS             complement(11461..12591)
                     /locus_tag="VVK04_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU3989204.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     CTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(12659..13357)
                     /gene="dapD"
                     /locus_tag="VVK04_000503"
     CDS             complement(12659..13357)
                     /gene="dapD"
                     /locus_tag="VVK04_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU3989205.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGSVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(13587..14498)
                     /locus_tag="VVK04_000504"
     CDS             complement(13587..14498)
                     /locus_tag="VVK04_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU3989206.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(14563..17028)
                     /locus_tag="VVK04_000505"
     CDS             complement(14563..17028)
                     /locus_tag="VVK04_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU3989207.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            17170..18426
                     /locus_tag="VVK04_000506"
     CDS             17170..18426
                     /locus_tag="VVK04_000506"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU3989208.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(18504..20567)
                     /locus_tag="VVK04_000507"
     CDS             complement(18504..20567)
                     /locus_tag="VVK04_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU3989209.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(20569..20847)
                     /locus_tag="VVK04_000508"
     CDS             complement(20569..20847)
                     /locus_tag="VVK04_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989210.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            21098..21946
                     /locus_tag="VVK04_000509"
     CDS             21098..21946
                     /locus_tag="VVK04_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU3989211.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAS
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            22568..23140
                     /locus_tag="VVK04_000510"
     CDS             22568..23140
                     /locus_tag="VVK04_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989212.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(24185..26443)
                     /gene="glgP"
                     /locus_tag="VVK04_000511"
     CDS             complement(24185..26443)
                     /gene="glgP"
                     /locus_tag="VVK04_000511"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU3989213.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVCSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(26469..27986)
                     /gene="malQ"
                     /locus_tag="VVK04_000512"
     CDS             complement(26469..27986)
                     /gene="malQ"
                     /locus_tag="VVK04_000512"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU3989214.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28536..29807
                     /locus_tag="VVK04_000513"
     CDS             28536..29807
                     /locus_tag="VVK04_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU3989215.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            29918..31210
                     /locus_tag="VVK04_000514"
     CDS             29918..31210
                     /locus_tag="VVK04_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU3989216.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            31212..32054
                     /locus_tag="VVK04_000515"
     CDS             31212..32054
                     /locus_tag="VVK04_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU3989217.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            32315..33115
                     /locus_tag="VVK04_000516"
     CDS             32315..33115
                     /locus_tag="VVK04_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU3989218.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            33125..34111
                     /locus_tag="VVK04_000517"
     CDS             33125..34111
                     /locus_tag="VVK04_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU3989219.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            34253..34456
                     /locus_tag="VVK04_000518"
     CDS             34253..34456
                     /locus_tag="VVK04_000518"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989220.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVVDETDEVS
                     SKHGFEVADRIDEVSNIYTARRR"
     gene            complement(34492..35433)
                     /locus_tag="VVK04_000519"
     CDS             complement(34492..35433)
                     /locus_tag="VVK04_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU3989221.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(35411..37174)
                     /gene="aspS"
                     /locus_tag="VVK04_000520"
     CDS             complement(35411..37174)
                     /gene="aspS"
                     /locus_tag="VVK04_000520"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU3989222.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(37526..37756)
                     /locus_tag="VVK04_000521"
     CDS             complement(37526..37756)
                     /locus_tag="VVK04_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989223.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(37774..38415)
                     /locus_tag="VVK04_000522"
     CDS             complement(37774..38415)
                     /locus_tag="VVK04_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3989224.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(38427..39161)
                     /locus_tag="VVK04_000523"
     CDS             complement(38427..39161)
                     /locus_tag="VVK04_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU3989225.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(39164..39361)
                     /locus_tag="VVK04_000524"
     CDS             complement(39164..39361)
                     /locus_tag="VVK04_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989226.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(39361..39567)
                     /locus_tag="VVK04_000525"
     CDS             complement(39361..39567)
                     /locus_tag="VVK04_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3989227.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(39577..39891)
                     /locus_tag="VVK04_000526"
     CDS             complement(39577..39891)
                     /locus_tag="VVK04_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989228.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(40161..40241)
                     /locus_tag="VVK04_000527"
                     /pseudo
     CDS             complement(40161..40241)
                     /locus_tag="VVK04_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(40232..41521)
                     /locus_tag="VVK04_000528"
     CDS             complement(40232..41521)
                     /locus_tag="VVK04_000528"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU3989229.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFATKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(41599..42846)
                     /locus_tag="VVK04_000529"
     CDS             complement(41599..42846)
                     /locus_tag="VVK04_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU3989230.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGSALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(43039..43890)
                     /gene="rgg"
                     /locus_tag="VVK04_000530"
                     /pseudo
     CDS             complement(43039..43890)
                     /gene="rgg"
                     /locus_tag="VVK04_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            44014..44355
                     /locus_tag="VVK04_000531"
     CDS             44014..44355
                     /locus_tag="VVK04_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU3989231.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            44413..44493
                     /locus_tag="VVK04_000532"
                     /pseudo
     CDS             44413..44493
                     /locus_tag="VVK04_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(44609..46312)
                     /gene="ilvD"
                     /locus_tag="VVK04_000533"
     CDS             complement(44609..46312)
                     /gene="ilvD"
                     /locus_tag="VVK04_000533"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU3989232.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIIDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(46557..47489)
                     /locus_tag="VVK04_000534"
     CDS             complement(46557..47489)
                     /locus_tag="VVK04_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU3989233.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(47486..48343)
                     /locus_tag="VVK04_000535"
     CDS             complement(47486..48343)
                     /locus_tag="VVK04_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU3989234.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(48347..49693)
                     /locus_tag="VVK04_000536"
     CDS             complement(48347..49693)
                     /locus_tag="VVK04_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU3989235.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(49706..49990)
                     /locus_tag="VVK04_000537"
     CDS             complement(49706..49990)
                     /locus_tag="VVK04_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU3989236.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(49994..52024)
                     /locus_tag="VVK04_000538"
     CDS             complement(49994..52024)
                     /locus_tag="VVK04_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU3989237.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEYYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            52215..53222
                     /locus_tag="VVK04_000539"
     CDS             52215..53222
                     /locus_tag="VVK04_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU3989238.1"
                     /translation="MTEKLINSKPNGVFALILIELTIILGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            53225..53425
                     /locus_tag="VVK04_000540"
     CDS             53225..53425
                     /locus_tag="VVK04_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU3989239.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            53577..53759
                     /gene="rpmF"
                     /locus_tag="VVK04_000541"
     CDS             53577..53759
                     /gene="rpmF"
                     /locus_tag="VVK04_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU3989240.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            53775..53924
                     /gene="rpmG"
                     /locus_tag="VVK04_000542"
     CDS             53775..53924
                     /gene="rpmG"
                     /locus_tag="VVK04_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU3989241.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(54416..>54525)
                     /locus_tag="VVK04_000543"
     CDS             complement(54416..>54525)
                     /locus_tag="VVK04_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU3989242.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT        16820 a        11642 c        10040 g        16023 t
ORIGIN      
        1 attcgctaat tgttttttta gggcgattga tttgtacttc cgtcgcatca atcattatcg
       61 tgtcctcaga gctgagagga gttcttgaaa tcgtaacacc actttgaaca agagttactt
      121 caacccattg gctccgacgg ataaagaaga cttgataaga actctagagt tagctcccca
      181 tgttgaaggt ggctatttta gacaaacaaa aaaagcttca gacactataa accttgctgg
      241 taagggaagg gcgctttata ccagtattta tttcttatta gaagaaacga atccttcaca
      301 ttttcaccga ttgacagcag atgaaatctg gtattttcat gcagaatccc cacttactgt
      361 tcacatgatt acagcagatg gtcactacga agcagtcact ttaggcctgg acatatccaa
      421 agggcaacaa cttcactact gtgttcctaa gggcactatt ttgggatcaa cagttgataa
      481 ggatgatgct ctggtttctt gtcttgttgc tcctggtttt gaatttgagg attttgaatt
      541 atttgaaagg gcagatctac tggcgaccta tccagagcac aaggagatga ttgagcattt
      601 gaccagatac tagtcttgat aagcaaattt aatctgattt agcaatgtta ggatttctga
      661 taattgtgtt ataatgttac caataggaga taatagatga caaaacaagt cttattagtg
      721 gatgatgaag aacacattct gagattactt gactaccatt taagtaagga aggcttttct
      781 actcaattgg taacaaatgg acggaaggcc ttagctttgg cagaaacaga accctttgat
      841 tttatcttgc ttgatatcat gttaccacaa ttagatggca tagaagtttg taagcggctg
      901 agagccaaag gcgtcaaaac tccaattatg atggtttctg cgaaaagtga tgaatttgat
      961 aaggttttgg ccttggaatt aggggctgat gactacctga ccaagccttt tagccctaga
     1021 gaattgctgg cgcgtgtcaa ggctgtcctc aggagaacta aaggagaaca agaaggagat
     1081 gattcagata atatcgctga cgattcttgg ctatttggga ccttgaaagt ataccctgag
     1141 cgtcatgaag tctacaaggc gaataagtta ctgagtttga ccccaaaaga atttgaactc
     1201 ttgctctatc ttatgaaaca tcccaacatg acactgacta gagagcgtct tttggaacgt
     1261 atctgggggt atgactttgg gcaggaaaca cgtttggtgg acgttcatat tggtaagttg
     1321 agggaaaaaa ttgaagacaa tcctaaagcc cctcaattta ttcgaaccat tcggggttat
     1381 ggttataagt tcaaggagtt atagatgaaa cgctaccttc aattttggct agtcaatcta
     1441 agtgttagcc tcattctgat tgcaggaatg gcattaactt ggatcagtaa aggcatcggt
     1501 ctctttcttc tagccctttc tttgggacta ggtggctact ggctcttttg cctttggaaa
     1561 tgggaagttg cttttgagac cttgcaccaa cctctcttga ccagtagtga atacttttta
     1621 gaaaaagggc aagaagactt aaagtctttg gctcagtatg tgtctggcct aaaaaccaaa
     1681 gtctcccaac aggatcagca atacaaggac ctagccgaaa caatggaggt tcttctgtcg
     1741 cacctaacca tggggacgtt tttagtttcc gctcaaggtc agatgttatt atccagtcgc
     1801 tctctgcctc attattttcc cgatgtggac ggcgacataa gttcacttga tgacctcaaa
     1861 cggatggata ttcggaattt agttcaccaa gcctttgatc aaaaaacaag gttaaaacaa
     1921 gaagtaagtg ggtttcatga gggtgacttg attttagaag tgacagcagt tcccgttttt
     1981 agccccaccc aatctgtgga agctgtgctc gtcttgctat atgatttaac aacgattaga
     2041 acttatgaaa agttaaattt agcctttgtc tcaaatgcct cccatgaatt gaggacacca
     2101 gttacttcga ttaagggctt tgctgaaacc attaagggga tgtcagctga agaagaagcg
     2161 ctcaaggatg actttctaga cattatttac aaagaaagct tgcgtcttga gcatattgtt
     2221 gagcatcttc ttaccttatc taaggctcaa caaatgccta tacaatggac gaccctttct
     2281 ttggcagaat ttgtacagga tttgactcaa agcttgcaac ctcagctcaa gaagaaggat
     2341 ttacagctaa aggtgcaggt gccagatgat gtcaccctcg tatcagatag tcaattactt
     2401 tcccaaatct tactcaatct tttatccaat gccatccgtt acactgaaca agggggaaaa
     2461 attgaggtca agacccaaaa ggtgaacgaa ggcattaaga tttctgtatc agatacaggg
     2521 attggtatta gtcaattaga gcaggatcgt atttttgaac gtttttaccg agttaataaa
     2581 ggtcgaagca gacaaactgg tggcactggt cttggccttg ccattgtcaa agaactcagt
     2641 caattattag gtggccaagt cacggtgacg agtcagcttg gcagaggcag ttgcttcacg
     2701 atttttcttc ctaaccaatc tttcgcacag gactaataat ttttaaagct atttttagga
     2761 gcagccattt ttcaaaagtg gctttttttg attctttaca caatctttac atgaatcagg
     2821 gataaacctt tacaaagact tgttagacta taaatgtagt aagcctacac aagaaaaata
     2881 catagagata aaggtgatta ttatgaaatt caaaaaaatg cttactcttg cagccattgg
     2941 cttatcagga tttgggcttg ttgcctgtgg caatcagtca gctgcttcca aacagtcagc
     3001 ttcaggaacg attgaggtga tttcacgaga aaatggctct ggaacacggg gtgccttcac
     3061 agaaatcaca gggattctca aaaaagacgg tgataaaaaa attgacaaca ctgccaaaac
     3121 agctgtgatt caaaatagta cagaaggtgt tctctcagca gttcaaggga atgctaatgc
     3181 tatcggctac atctccttgg gatctttaac gaaatctgtc aaagctttag agattgatgg
     3241 tgtcaaggct agtcgagaca cagttttaga tggtaaatac cctcttcaac gtcccttcaa
     3301 cattgtttgg tcttctaatc tttccaagct aggtcaagat tttatcagct ttatccactc
     3361 caaacaaggt caacaagtgg tcacagataa taaatttatt gaagctaaaa ccgaaaccac
     3421 agaatataca agccaacact tatcaggcaa gttgtctgtt gtaggttcca cttcagtatc
     3481 ttctttaatg gaaaaattag cagaagctta taaaaaagaa aatccagaag ttacgattga
     3541 tattacctct aatgggtctt cagcaggtat taccgctgtt aaggagaaaa ccgctgatat
     3601 tggtatggtt tctagggaat taactcctga agaaggtaag agtctcaccc atgatgctat
     3661 tgctttagac ggtattgctg ttgtggtcaa taatgacaat aaggcaagcc aagtcagtat
     3721 ggctgaactt gcagacgttt ttagtggcaa attaaccacc tgggacaaga ttaaataaaa
     3781 tgtttgctcc ataaatctct aaagagatgc agacgtttca tcgtacaata agataaagaa
     3841 ggcaagtagg gaggtgtcgt atctccctta ctttcttcac tagaaaggac aagatgtgac
     3901 aaaacaagcc ttcaaagaag cagtttttag ggcaattttt ttcatgagtg caacagtagc
     3961 tgttgtagct attttgctaa tctgtttctt tatttttagt aatggcttac ctttcatagc
     4021 taactacggc tttgcccgtt ttttattagg cagtgattgg tcgccaacga acattccggc
     4081 aagctatggt attttaccaa tgatcgttgg ttccttatta attaccttag gagcgattgt
     4141 gattggggtg ccaacaggca tcttgacatc ggtgtttatg gtttattatt gtccaaagcc
     4201 cgtctatggc ttcttaaaat cagctatcaa cttgatggca gccattccat ctattgttta
     4261 tggttttttc ggcctacaat tattggtgcc ttggattaga agctttttag gaaatggcat
     4321 gagtgtccta accgcttcgt tactattagg aataatgatt ttgccaacca ttatcagttt
     4381 gtcagaatct gctatccgaa cagttcccaa aacgtattat tctggtagct tggctctagg
     4441 agctagtcat gaacggagta tttttagtgt catcttgcca gctgcgagat ctggtatttt
     4501 atcagcagtt attttaggaa tcggtcgcgc agtaggtgaa accatggcag ttattttggt
     4561 ggcaggcaac cagccaatta ttccaagtgg actcttttca ggaaccagaa ccttaacaac
     4621 caatattgtt ctggagatgg cttacgcatc aggtcagcat agggaagccc ttattgcaac
     4681 ctcagcagtt ctctttttcc ttattctctt gattaatgcc tactttgcct acttgaaagg
     4741 aaaatcatct tatgagtaaa tacctgctaa aacttctcgt ttattgtttt tcagctttaa
     4801 cctttggctc tctcttttta atcattggtt ttatcctcat caaaggctta cctcatctaa
     4861 gtctatccct cttttcttgg acttatactt ctgagaacat ttcccttatg ccagcgatta
     4921 tttccaccgt tattctggtc tttggtgctc ttcttttagc cttgcccata gggatttttg
     4981 ctggttttta tcttgtggaa tatacaaaaa aagattccct ttgtgttaaa atcatgcgat
     5041 tggcctcaga taccttgtct gggattcctt ccattgtttt tggtctgttt ggcatgctct
     5101 tctttgtagt cttcttaggt tttcaatact ctctgttatc aggaatctta acctcagtca
     5161 tcatggtgtt gccagtcatt attcgctcaa cagaagaagc ccttttatct gttagtgata
     5221 gcatgcgtca agcaagttat ggacttgggg caggtaagtt acggactgtt tttagaattg
     5281 ttctaccagt tgccatgcca ggtattttag ctggagtgat actagctatt ggccgtatcg
     5341 ttggtgagac agctgccctc atgtatacat taggtacctc taccaatacg ccaagtagtc
     5401 tcatgtcttc aggtcgttct ctagccctgc atatgtatat gctgtcaagt gaggggctac
     5461 atgtcaatga agcctatgct accggtgtga ttttgattat tactgtttta atgataaata
     5521 ctctatcaag cttattatct cgaaaacttg tgaaaggagc ttcctagtat gggaacattt
     5581 tcagttagac acctagactt attttacggg gattttcaag ccttaaaaaa tatttcgatt
     5641 caattaccag aaagacagat tactgccttg ataggcccat ctggttgtgg caaatcaact
     5701 tttctaaaaa cccttaatcg gatgaacgat ttggttcctt cttgccatat tgaaggccaa
     5761 gtcctcttag atgagcaaga tatttatagt agcaaattca accttaatca gctacgcaag
     5821 cgtgtaggga tggtttttca acagcctaat ccctttgcca tgtctatcta tgataacgtg
     5881 gcttatggtc caaggacaca tggtattcga gacaaaaaac aattagatgc cttagtggaa
     5941 aaatctttaa aaggggcagc catttgggac gaagtcaaag ataatcttaa aaagagtgcc
     6001 atgtccttat caggcggtca gcagcaacgc ctttgcattg cgcgagcttt agcagtagaa
     6061 cctgatgttc tgttaatgga tgagccgact tcagccttag accctatctc cactttaaaa
     6121 attgaagacc tcattcagca actaaaaaag gattatacga ttatcattgt tacccataac
     6181 atgcaacaag cttcacgtat ttcagataaa actgcttttt tcttaacagg agaaatttgc
     6241 gaatttggag ataccgttga cgtgtttacc aatccaaaag atcagcgcac agaagactat
     6301 atttcaggac ggttcggata aggaaggaaa aacctatgag aaatcaattt gacttagaat
     6361 tgcatgaatt agaacaatcc tttttaggac tagggcaact tgtccttgaa acagcttcaa
     6421 aagccttact ggccttagcc tccaaagaca aggagatggc agagctaatt atcaataagg
     6481 atcatgctat caaccaaggt caaagcgcta tcgaattgac ctgtgcccgt ttgttggcct
     6541 tgcagcagcc acaagtgtct gaccttcgat ttgtaattag catcatgtct tcttgttcag
     6601 accttgaacg tatgggagac catatggcag gcattgccaa agctgttttg caactaaaag
     6661 aaaatcaact agcccctgac gaagaacagt tacaccaaat gggtaaatta tccctcagca
     6721 tgctagccga tttattggtt gcctttcctt tgcaccaagc ctcaaaagct attagtattg
     6781 ctcaaaaaga tgaacagatt gaccaatatt attatgcctt atcaaaggaa atcattggac
     6841 ttatgaaaga ccaagaaacc tcaattccca atggaactca atacctttat atcatagggc
     6901 atctggaacg cttcgctgat tacattgcta acatttgtga acgcctagtc tacctagaaa
     6961 caggagaact agtggatttg aattaattca actaatcctt aaaagagaag agtacgatta
     7021 agtgctcttt tttatggttg taaaaaagtt catttgacca atttaagcag tgtagatagt
     7081 gaggagctgt ttcaattcta tcgtgaacga gggaatgctg aaaactttat caaagaaagg
     7141 aaagcaggat tctttgggga taagacagat agttcgacca tgattaagaa tgaagtacgt
     7201 atgatgatgg gctgtctggc ttataatctc tacctctttt taaagcagct agctggtgat
     7261 gaagtaaagg ccttgactat caagcgtttt cgacgtctct tccttcatat tgccggaaaa
     7321 tatgtctcta ctgctagacg acatattctc aaattctcaa gtctatacgc ctattcaaaa
     7381 cagtttcaag ccttatttga tacaatctgc cagataaatc tgatactccc tgttccatat
     7441 agagctagag ggcaggggaa aacatgccta acagaataag tcaccttatt ttaaaaatcg
     7501 agcatcaaac caagggagga gtctgccctt ttttaggaaa aaatcaagac aaatctcctc
     7561 aattatgtct cgaacatcag aaattaagca aaatcaccag aaggacagta tttcaactag
     7621 cttttctggt aatttttgaa ctgtgtagtt cgttagtgcc agatatgaat aatttgggat
     7681 gataaatctt tcttcctcag gtagcctatc ataatactct tcaaaaatct tatcaaaaca
     7741 ctctctttct tttgggcgat agtttcatct tcgtatgtag gagtcctcat caagaaatac
     7801 ttcaattcta ggtattcctt atccaactct atataacttg gcatcaactt gtaatcttca
     7861 acccccaaac gttcagcgat atattttaac tttgttagtg ttggtctgga ttctccattt
     7921 tcaattctaa ttaattgacg gatacttaat tcagactcat caccacaaaa ttctgaacga
     7981 ctgatttttt tagccaaacg taatctttta attttttcgc caaactctcg caacctacaa
     8041 gaacctcctg agttgtttac ctctattata agcatatact gaatcaaact atctatcaga
     8101 tttcttctca ctttaactaa agactaagag tttatccctt cgtctcggtt tttgtgtatt
     8161 tttccaccat accccagtaa tgcaagtgca aaatccccta gaatatgata gaataagaga
     8221 aagaactcta tcaaggagga aatcatggaa aaacaaaccg tcgccgtctt ggggcctggt
     8281 tcttggggaa ccgccctttc acaagtctta aatgacaatg gacacgaggt acgtatttgg
     8341 ggaaatcttc ccgagcaaat caatgaaatt aatacacacc atactaataa gcactacttt
     8401 aaagatgtcg ttctagacga aaatatcatt gcctacaccg acttagcaga aacattgaaa
     8461 gatgtggatg cgattttgtt tgttgtccca acaaaagtga cacgacttgt tgcccagcaa
     8521 gttgcacaaa ccttggacca taaggttatc atcatgcacg catcaaaggg attagaacct
     8581 gatagccata aacgattatc aaccattctt gaagaagaaa ttcctgaaca tctccgtagt
     8641 gatatcgtcg ttgtttcagg gcctagtcat gcagaagaga ccattgtgcg tgacctaact
     8701 ttaataactg ctgcttctaa agatttacaa acagctcaat acgttcagga gctatttagt
     8761 aatcactact tccgacttta taccaatacg gatgttatcg gggttgaaac tgctggtgct
     8821 cttaaaaata ttattgctgt cggtgctgga gctttacatg gtcttggatt tggtgataat
     8881 gctaaggcag ccatcatcgc tcgaggttta gcagaaatca cccgcctagg ggtagcactc
     8941 ggggccagtc cattgaccta tagcggctta tctggtgtgg gagatttgat cgtaacggga
     9001 acttccatcc actctcgtaa ctggagagct ggagatgctc tcggacgagg agaatcccta
     9061 gctgatatag aagctaatat gggcatggta atcgaaggaa tttcaacgac tcgagcagcc
     9121 tatgaactag cccaagaact tggagtctat atgcccatta cacaggctat ttaccaagtt
     9181 atttatcacg gaaccaatat caaagatgcc atttatgaca tcatgaacaa tgaatttaaa
     9241 gcagaaaatg agtggtctta accctctata gaaaggattt ttatgacatc aaaagttaga
     9301 aaggcagtta tccctgctgc tggactagga actcgatttt taccagcaac caaggccctt
     9361 gccaaagaaa tgttgccaat cgtagacaaa ccaactatcc agtttatcgt ggaagaggct
     9421 ctcaaatcag gtattgaaga tattctagtt gtcactggta aatcaaaacg ttctattgag
     9481 gaccacttcg attcaaactt cgaattggaa tataacctca aagaaaaagg gaaaacagat
     9541 cttttgaagc tagttgatga aacaactggc atgcgtctgc attttatccg ccaaactcat
     9601 ccacgcggtc tcggagatgc tgttttgcaa gccaaggctt tcgtcggaaa tgaacctttt
     9661 gtcgttatgc ttggtgatga cttgatggat atcacagacg aaaaggctgt tccacttacc
     9721 aaacaactca tggatgacta caagcgtacc cacgcgtcta ctatcgctgt catgccagtc
     9781 cctcatgacg aagtatctgc ttacggggtt attgctccgc aaggcgaagg aaaagatggt
     9841 ctttacagtg ttgaaacctt tgttgaaaaa ccagctccag aggacgctcc tagcgacctt
     9901 gctattatcg gacgctacct cctcacgcct gaaatttttg agattctcga aaagcaagct
     9961 cctggtgctg gaaatgaaat ccaacttact gatgcaatcg atactcttaa taaaacacag
    10021 cgtgtttttg cccgtgaatt tacaggagct cgttacgacg ttggggataa gtttggcttt
    10081 atgaaaacat ctattgacta cgccctcaaa catccacaag tcaaagatga tttgaagaat
    10141 tacctcatcc aacttggaaa agaattgact gagaaggaat aaaataaaaa gataaggttc
    10201 aaaaaatgcc ttatcttttt tcattacaca aattttcttt caacttcgtc acattcccat
    10261 tcccttgtag aaaagcaaaa tggcgagtcc tacgaacaag actaccgctc ctaatctctg
    10321 gctggtatta tacatccgtt tttctcctct aactggaaag ataactgcta gaaatgcgcc
    10381 accaactgca ccaccgatat ggcctgctag gctgatttct ggaatcagaa cacttccaat
    10441 aatgttaacc acaaaaagtg tcagatagga ttgccctagc tgttgaatat aaggattgcg
    10501 agttgcatag cgaagaacaa taatcgcggc aaatagccca taaagagagg tagaggcgcc
    10561 tgctgctaag gatttaggac taaatacaaa aacaaagaga ttgcccatca ttcctgataa
    10621 gagatagaga aagaaaaact gcttagaacc gaaaatctcc tctacctgcc ttccaagata
    10681 ataaagtgaa agcatattaa caatgaaatg ttcccaccca atatgaacaa aaatggcaga
    10741 caagagacgc caaacctgct cgggaaagag gcgaatagct ggcccataca tggctccaaa
    10801 tcgaaataat gtatctgccc tgtcaaagtt tccgcctgca gtgaccaaca ttagtaaaaa
    10861 taccaaggcc gtcactaaga ggaagaaact cgtcacaggg taacgtctat caaagatttc
    10921 cttcatcaat taatacctcc tgaacaggaa tatcatggtt ttcaggtata aagtcctgaa
    10981 tttgacaagg atatatcgta ctcaaagtac gaccagaaaa atgttccaga tagcggtcat
    11041 aatagcctcc accgtatcct atccgatatc ctttcgtcgt aaaagccaga ccaggaacat
    11101 gaatcaaatc aatctgagat gcatccacta cttccaaatc tccctgtagc tccagtaagg
    11161 caaaggaagt ttttaccaac tgttgcggat catagaccac aaaatccatg cgccccttgg
    11221 gataggtctt aggtgtcaaa accttcttgc cgtccttcag cgcctgctca atcagttccc
    11281 gcgtttgaaa ctcatgagaa aaagagaggt aggttgcgat gaccttggct tcttgataaa
    11341 aggggtgttg taaaattcgc tcggttaaag cttggtctat agcctgtttt tgttcttgag
    11401 ataaagtctt catttcatgc aagacttgct tgcgtaattc cgatttcata gacaagccct
    11461 ctattctgct gccttctttt tcaggaaact agacaccgca gccaccccaa tagctaagac
    11521 ttcttcctta ggactcattt gagggtgatg aagagcgtag ggactatcga tacctagcca
    11581 aaacatcacg ccatcaacct ttgaaaggag ataaccaaag tcctcgcctg tcatagcagg
    11641 ttcgatatca atcaactcga ttccgtcttt ttcgtcaaag aagtccatca gttcacgcgc
    11701 caaggctgga ttgttctcaa caggtaggta tccaccttgt ttgagttcca cttcgacttc
    11761 catatcaaag gcagctgcaa ccccttctgc aactgttttt accctctttt gcaccaagag
    11821 actcatgtcc tgtgtcaagg cacgaatagt tccatgtaaa aaagctgtgt ctgtgatgac
    11881 attgttggtg gttccagctt gaaaaacgcc gaaggtcacc actgctccct cgattgggtt
    11941 gacattgcgg ctaacaactg actgcacttg ggtcacaaag taactagccg ccaccaaggc
    12001 gtcattggct tcatgaggaa aagctgcgtg gccacctttg cctttgaaac ggatcttcac
    12061 ctcgcaagtt cctgcaaaga gtgtatgagt attagtcgca atctggccga ctttcaaatc
    12121 tggacgaaca tggagaccat agaattggtt tggcaaccaa tctccaaaag caccgtcctc
    12181 atacatgagc ataccaccag cttcattttc ttcagcaggc tgaaatagaa agagcagatt
    12241 attcttgggt tgctcctcaa gggcgcgctc aagacagcct aaggcaatgg tcatatgaaa
    12301 atcatggcca caggcatgca tgcgaccttg gtgttgagaa gcaaaaggta gacctgtttg
    12361 ttcgacgata ggcagaccat caatatctgt ccgccaacca atggttcgct ccggctgact
    12421 tccctgcagg tagaccaaaa tccctgtccg ccaagtacaa atttgaacaa aatccttgcc
    12481 cgtagtcaat ttctcaatca catccagcaa ataagcctga gtcttgaact cctccaagcc
    12541 aatctctggt atctggtgta aagctcgtct agtctgaatc aaatctaaca tctatctgtc
    12601 ctccgatata gcagaaagag gctggaaaaa gggttccgcc tcttttttac ttttacaatt
    12661 acaaggtacg aagcgcatcc tctagcgctg ttttttgttg ggtttgggca tcaatttctt
    12721 tgatgatacg agctggaaca cctgctacta ccacgttttc tgggacatct tgggtaacga
    12781 tagctcctgc agcgacaact gaaccactac cgatttggac tccttcgata accactgcat
    12841 tagcaccgat aagaacattg tctccgacac ggactggttc agcactagct ggctcaatca
    12901 cacctgccaa aactgcacct gcaccaacgt ggctattttt tccaacgatg gcacggccac
    12961 caaggatggc acccatgtca atcatggttc cagcaccgat ttcagcaccg atattgataa
    13021 cagatcccat catgataaca gcattgtcac caatttccac ctggtcacgg ataatagcac
    13081 ctggctcgat acgagcgttg atagcacgct tatctagcaa aggaactgca gaattacgag
    13141 catcttgctc gacaacataa tcttgatttt ctaccaaacc ttcaagaagc ggagccacgt
    13201 ccttccagtc tccgaatagg acatttccta gtttgacaac agagctaggc acagcagttg
    13261 cgagttgccc ctcaaaggtt actttgacac tggttttctt ttcagcattg gcgataaatt
    13321 ggataatttc ttgagcgttc atttttgtag cagtcatagg tgcctcctgg ttcgttataa
    13381 tgatacctat tctaccaaaa aaggcctcaa atttgaaacc tttttgtctg tttttaggta
    13441 tgatttttta gggatgtgag ataaaacgtg ctgtcggtaa aagcaagccc ctaccgatac
    13501 aacctaaaaa cactcttcac aactatctcc ccgtgtttta ttgactattc tagtatagca
    13561 cacttttaga attaagaaaa gactttttat ctactttctt tcgcttcttc tatagacaaa
    13621 aatatcatgg gtaaaataat caaggctata gctagaagga gggaccaatc cactactaat
    13681 cctaagaaca aaacactcaa gagagcagaa gagagaggtt cactggcact gataacggca
    13741 accaccaaag gagaaaccaa ggacacagcc ttcatggaaa tgaaaaaagc aaaagccgtt
    13801 ccaaagaaag cgataatgag gcaaatcaag atactccaaa tatcaagagt aaaggaaagc
    13861 tgataaaccg gcgagaggac attgctaaac aaaccggcca aaatcatccc ccacccaacc
    13921 gtaggaacaa aaccataacg cttagcaaaa ggttggggca agataacatt aaacataaca
    13981 cccatggcac tcagcaaacc tgttataaga gctagcggcg tcatggataa ctgagagaga
    14041 tctccctttg tcgccatcaa gcaaacaccc agcatggcaa ccaaaacata gaaaacagcg
    14101 ctttttgacg ctcgtttttg ataaaccaag cgattgtaaa agaggataaa gacagggcta
    14161 ataaactgta aaatagttgc tgtcgtagca tttgagtatt ctacacagag atagaaaaaa
    14221 tactggactg aaaaaatccc caaaatagca taggctaaaa agggcaggta atttttcttg
    14281 tctcgccaaa tatctagcac ttgcgatttt aattgtattg cagaccaaat gagtacaaga
    14341 ctccctgcca gtgtcaaacg catagaggta atccagcccg aagacacctg ataatgagta
    14401 aagaagtact ctcctaaaat tccacagatt ccccatatta agccggatag gagcgaataa
    14461 atttttccgt taacaatctt tttctgatac tgattcatac ccttattgta acacgaaaag
    14521 aaaaaagtgg caatccattg attggccact tcatttagag aattatcgtc tcgcccttga
    14581 agaagaaggt cgtgtagtac ttgagttact gctatcgcta gaactactac ttgaactgct
    14641 ggagctggat ggagttggta gactccccac aatactagac caagcattct gataatccgc
    14701 atcacttccg ccaatagcaa agcgataact tgtcgctggc gctcctgact tattagccca
    14761 atagctggta acagtcgaac ctgtgacctc tacctctttt ccttcaacag aaaccttccc
    14821 tggtttttga cctgttgatt tcaagacttc cgatttcact acactaggat ctaaagcaaa
    14881 gcgctcgttc ccccaaatgc ttggggaagc ttgctgaatc gcatttacca gatgagccat
    14941 gtaattagag ttattagaat aacctgctct acgtgacaat gaatgattat catcatgccc
    15001 aatccagcca cctagggtta atctaggtgt cgaaagcatg agccacatat tttcgtcttg
    15061 gttggttgta ccagtcttcc caatccaatc tgcattagcc agagtaggat ttaaagaagt
    15121 caggttagac ttgaaggttg ttgtcacacg agaggataga acttctcgta gcaatccctg
    15181 cataatcgtc gcagtagctt ttgaatagac ttgaaccggt ttatcctgat actcatacac
    15241 cactctacca tctgctgctt caatctttga aatcacatgc ttctgatgat aaactccatt
    15301 attagctaag gtctgatagc cattggtatg ctgggcaact gtgacttcaa taccaccacc
    15361 cattggcaag ctctcaatac cgtactcagg aatctcgtaa cccatctttt ccatataacc
    15421 cttgacatca acaccctttt cacggagcat acgataggtc cagtaagcag ggatattcca
    15481 tgaatagttc agagcttctc ccaaggtcat cattcctgtt cccttgctat tagcatacat
    15541 aatcggattg ccattagcaa agtttgttgg atagttagat agaatcgttt cacttcccat
    15601 caagccctgg tcaatagcaa taccgtaggc cagcaagggc ttggtagtag aagctggcga
    15661 acgtttggta tcaaaggcat gattattttg attttcttga taattacgac cacctacaaa
    15721 gcctagaata gcacctgttt ggttgtccat caagacattc cctacttcta cacgacctgt
    15781 tccatcgtct aaaagatagc cataatcagc aaccgcactt tgcatggcag aatgaatttt
    15841 ctgatctatg gtagtagtaa tcttataacc accattttca atttccttgg ctgccaaatc
    15901 tcgataaaac ttctgagttg cctcattttt caactcctta gcggagacat tgtctctctg
    15961 agctagatag tcatacatac gttcttgagc ttctgccaaa gttgtaaagt ataaatagtc
    16021 tcgtgaaatt cctgtaaccg tgcccgatgg taaaaagtcc tgtttaaggt cataatcctt
    16081 gtactgagaa tactcgtctt tgcttaatgc acctgtacga tacatactgt aaagaactgc
    16141 cttagcccgt cttaagccaa tttctaggtc ttcatcactc ttcaactccc cagtattttc
    16201 ataaggagag taagtaatgg gactctgtgg aagtcctgct aaaaatgctg cttgaggaac
    16261 agtcaactga ctggcatcta caccgaaaat tccctcagct gcttgccgag cccctgcaat
    16321 attctgtccc ttattatttc ggccaaaggg agccacattg agataggtcg ttaaaatctc
    16381 atctttattc atggcgcgtt ccaaggcaag agcatccaca atctctgccg ccttacgagc
    16441 caaggtcggc gcatccccaa caacctgctg tttaattagt tgctgggtca aggttgaacc
    16501 cccactagag gaacccaaac ctacaaattt ccccaaggtc gcacgaatca ccgccttggg
    16561 tactacaccc ttatgttctt taaagtgttc atcttctgtc gcaatgatag ccttcttcag
    16621 attttccgaa atttgctcag atgagataga agtgcgcaac aaatcactct ctatggaagc
    16681 aatcaccgtc ccgtccgaat aggtaatctc tgaaatagaa gagatgtcct tgacctgatt
    16741 caccaattct tctgtctgag gcacccgaac cttgtcaaat aaggccactc cgtatcccaa
    16801 agcaatccca gctcccaaca ttcctcctag aaaaccgagt acaaagagta agttaaataa
    16861 ggcttttata ctcagtaaaa tagctgggaa aatggctgac ttatctaagg ttttagattt
    16921 tttggtactt gaacctttct tgccaggtct agctgatttt ttattttttt gtttttgctg
    16981 gaaaaattcc agcatttttc gttttaattc atttaattga ttttgcatgg atttcctcac
    17041 tctatctatt ataccacaaa agggaaattt tcaataaaat agccactttc ttccctattc
    17101 tgctaggcta ttgcccaagt ttgtgataca ataggtagaa acaataattt taaaaaggag
    17161 aaaagacaca tgcacatttt tgatgagcta aaagatcgtg gtttgatatt tcaaacgact
    17221 gatgaagaag ctttgcgtaa agccctagaa gaaggtcaag tttcttatta tactggctac
    17281 gatccaactg ctgacagcct tcacctaggc caccttgtcg caatcttgac aagtcgtcgc
    17341 ttgcaactag caggtcacaa accttatgcg ctcgttggcg gtgctacagg tctcatcgga
    17401 gatccgtcct tcaaagatgc tgaacgtagt ctccaaacaa aagacacagt agatggctgg
    17461 gtcaagtcta tccaaggaca actttctcgt tttcttgact ttgaaaatgg cgaaaacaag
    17521 gctgtcatgg tcaacaacta cgactggttt ggcagcatca gcttcattga cttcctccgt
    17581 gacattggaa aatacttcac ggtcaactac atgatgagta aggaatctgt taaaaaacgg
    17641 atcgaaacag gaatttctta cactgagttc gcttaccaaa tcatgcaagg gtacgacttc
    17701 ttcgtcctta accaagacca taatgtcact cttcaaatcg gtggttctga ccagtgggga
    17761 aatatgacag ctggtaccga attgcttcgt cgtaaggcgg acaagactgg tcacgttatc
    17821 actgttccac taatcacaga tgcaactggt aaaaaatttg gtaaatcaga aggaaatgcc
    17881 gtctggctca atcccgaaaa gacttctcca tacgaaatgt accaattctg gatgaacgtg
    17941 atggacgctg acgctgttcg cttcttgaaa atctttactt tcttgtcact tgatgagatt
    18001 gaagatattc gtaaacaatt tgaagcagcg ccacacgaac gcttggctca aaaagtcttg
    18061 gctcgtgaag ttgttacact tgttcacgga gaagaagcct acaaagaagc acttaacatc
    18121 actgagcaac tctttgcagg aaacatcaaa aacctttctg tcaaagagct caaacaagga
    18181 cttcgtggtg tgccaaacta ccaagtacag gcagacgaaa acaacaatat cgtggaactg
    18241 ctcgtctcat ctggtatagt taactcaaaa cgccaagccc gtgaagacgt ccaaaacgga
    18301 gccatctacg taaacggcga ccgcatccaa gaccttgact atgtcttgag tgacgctgat
    18361 aagttagaaa atgaactgac tgttatccgt cgtgggaaga aaaaatactt tgtattgact
    18421 tactaaacta ttcaacattt atctataaac aaaggagtta acctcgagaa aggtaactcc
    18481 tttttgctgt taataactct catctatcta tttttaatag acaggctacg caggacaatg
    18541 cgcaaggttg ttagattatg taagatagag agatttgaag gactgaacca attaaataag
    18601 ccaaagccaa tcaaactact atttacgaca acggtatcct gaatattttt cttgatgagt
    18661 gtttgcaaag atgatgataa cgaatccaac tcttggaaga aatccaaacg attatctaac
    18721 aataagatat cactcatctg cttagaaata tctgcactct cattcatcac cacaccgata
    18781 tctgatagag ttaaagccgc tgagtcattc aatccatctc cgaccatcaa aatagtgtga
    18841 cctgctttct gcagtttctc tactaactca aatttcccat caggtttcaa gtctgtatag
    18901 acctgatcaa agggcaaatc tttgactaat tcctctgtcc taatcaaggt gtctcctgtt
    18961 gccagaatca attttttccc ctgtgcctta agtttatcca aggctgtttt tgcttctttt
    19021 ctcaaaggag tatgaatgca gaacattcca atcaattcat tttgataagc caagaataag
    19081 agattgtagt gactcttgta ctcttcaatt aaagcatttt gttctgaact gatatgaatc
    19141 tgctcatcct gcatcaagac ataattccca ataagaactg gttggccatc tatatgagat
    19201 ttgatcccct tgcttgcgat atattggagt ttcccatgca tttcctcatg ttcaattccc
    19261 tctatctcag cttgcttgac gatggcatta gcaataggat gataaatgtg ttcctcaaga
    19321 caggcactga ttctgagaat atcttcctca ctatagtctc caaaaggtaa caccttttca
    19381 actataggat aactagttgt gattgttcct gtcttatcaa acaagaaagt atcaacttcc
    19441 agatatttct ccagaacatc tccatcctta atcaccattt cacggttcaa cccttccttg
    19501 ataactgtca aataagctac aggagtagag attttcaaag cgcaggagaa atcgaccaat
    19561 aggaaagaaa tagccttaga aaaagaacct gtcaataggt aagtcagccc agcccccaag
    19621 aaattatatt tgacgacttt atccgccatc ttgatgaaat agcgttgttt cgttttcttg
    19681 ttttcttcag atttcttcat caactcaatc agctgtaaaa tacggctgtt catctgatta
    19741 tctgttacac gaatgcgtaa ctctccagtt tctaatactg tatttgcaca aaccaaatca
    19801 gactctcttt tttcaactgg aaaactctct cctgtcaagg aactttcgtt gaccatacct
    19861 aaacctgaaa ctacttgtcc atcaaacaga atttcatttc cttgagataa gatcaagaca
    19921 tctcctattt gaacatcgga actcttgata ctaacaaccg tatcgccctg tactaggaat
    19981 acatcgctct cttttgcaag aagactctgt tctaaatctg ttgcagtttt tttcaaggac
    20041 cactgatcta aatgattccc caaatcaagc ataaacatga tattgctagc tgtcttggat
    20101 tggttcataa acaaggacaa taaaatagcc gaacagtcca agacttccat cgttagttcc
    20161 ttacgcgcta gtgtttgata ggcttctcta atataaccca aagcctgata acaagtccat
    20221 atatagcgaa taggatacgg cacaaaacta cgaaaaagta cacgcttaac cgctgcacct
    20281 gaaacaatag aataagcact ctcttctcta cgaatgggaa gagtcatcaa ctcagaaact
    20341 ttccctttat caattctttt taaaaaggct tctgcattat ctaatacaga aaagccttct
    20401 tttatgcgta gagtaaagtg ctgttgatcc atgtaaaact ggatagactc aatccccttt
    20461 tcatctctcg ccaaggaacg aagatagtct tgaatatcca aggtaagtga aaaagaagat
    20521 gatagtcgga tatgttggta tcctctatgt agcactttaa aagacatatt attcacctat
    20581 aaggctatct aattgctctt cttttttctc ttgctcgtac aaatatttgg catcttgcaa
    20641 gacatcgtct ccatgttgct tcacaacaga aacagatgca tctagctcgt ctttcaactt
    20701 gtaagcctta gccaaagctt tagaataacc ttttttagct tccttacttg ctaagatttt
    20761 caaaccaagg gtaccaaatg cgacaccacc caaaaataat gaagattttt tcgcaacttt
    20821 tgcaacggtt aatacttctt ttaacatact tatttcctcc ttatcattat tatatagcaa
    20881 tttagatata aaagcaattt cattctataa attggagaat tatactcaat gaaaatcaaa
    20941 gagcaaacta ggaaactagc cgcaggctgt acttgagtac ggcaaggcga cgttgacgtg
    21001 gtttgaattt gattttcgaa gagtattagt tttatttcta ctgaatctac ttattcctaa
    21061 agttgctttc atttgcctct tttgatacac ttaaactatg aatacaaatc tcaagcccaa
    21121 acttcagcgt tttgcttctg cgactgcctt tgcctgtcct atctgtcaag aaaatctgac
    21181 tctgttagag actaatttca agtgctgcaa ccgtcattct tttgacttgg cgaaatttgg
    21241 ctatgtcaat ctagcacctc aaatcaagca atctgctaac tatgacaagg aaaattttca
    21301 aaaccgtcaa caaatcctag aagccggctt ttaccaagct atcttagatg ctgtatctga
    21361 cttgcttgca agctcaaaaa ctaccacaac aattttggat atcggttgtg gtgaaggatt
    21421 ctattctcgc aaactacaag aaagtcactc tgaaaaaact ttctatgcct ttgacatctc
    21481 caaagattca gtccaaatcg ctgctaaaag tgaacccaac tgggcagtca attggttcgt
    21541 tggcgacttg gcacgccttc ctataaaaga cgctagcatg gatatcctgc ttgatatctt
    21601 ctcacctgcc aactatggag aatttcgtcg cgttttatcc aaagacggta tcttgataaa
    21661 ggttatccca actgaaaatc acctcaaaga aatccgtcaa agagtacagg accagctgac
    21721 aaacaaggag tattctaacc aagatatcaa ggagcatttc caggaacact ttaccatcct
    21781 atctagtcaa actgcctctc tgactaagac tatcacagca gaacaactcc aagccctact
    21841 cagtatgact cctctcctct ttcacgttga ccagagcaag attgactgga gccaactgac
    21901 agagattacc atcgaagcag agattttggt tgggaaagca ttctaaacta gacttcccaa
    21961 aggtataaaa cttaccgaaa atcttcaata ttataaaaac gcataagaac aggtacacaa
    22021 accttaatct tatgcgtttt gttatagttt ccatacacat taaggggaaa tagttgaaat
    22081 cagttctctt aataaccatt gaataccata tactacattt accccaaata tgatataggc
    22141 cgtataaatc aagtatttcg atttttcccg cctcaaagaa tagatcttat acaaaataaa
    22201 taaatttaaa ataataaata atagagacaa aatcttcctc caaaatcaat attaaaagta
    22261 gccagtcaat catagttcta atctttattt tcgattcgaa attacaaact tatcaatgaa
    22321 caataagtga tataaggcca gtaccagacc ccaaacgcta ccacgaaaag agaattcttg
    22381 atgattgaga gtaaacaaat catggttacc aatatagagg caggtcaaaa taacaaataa
    22441 aatccaaaat aaatccgtcc atttatattt tgaaaaatat ttttttaaca taatagcata
    22501 tttttttgac tataataaca gtatatgata aaatgtaagc agatacaaat aaaaaggaga
    22561 aaagctcatg aacaaattaa tgaaatttat ttcggttttt ttgacgtcaa ttgtgttaat
    22621 tgtatcagcg attccaagtg tttcagctgt atacgcttct gaacaagtat cacaaattga
    22681 aacaaatatg gaacttcaac ctgtcacttc tctaacagaa gaacaaatca atacacttgc
    22741 aaacgaaatc caatcttttc atccagacgt ctcacaacaa tggatcaaag aagtaattaa
    22801 ccgacaatta caaggcgatt atacaatccc acctacatac tctccattta gagcagcttg
    22861 gcaaggtatt acagttaatc aaatgggtgc tctattagat actgcaatag ctttagcatt
    22921 aggaggaact actgcaggcc ttgcaaatct aattaaagta aaaggaaaac atgcagcaaa
    22981 aagtgctatt cgttcagcaa tttctagata tctaggtagt tggtttgtaa atgatgttgc
    23041 tttagaattc gctatgaatt tattatcacc ggggacttat ttagcacaat tatgggataa
    23101 aaatgatgcc attcctaaca acggaaggat taacttttaa tcatgagata tacaataaaa
    23161 ttaattgggt ataacgtatt ttcgttgttt atattcttta tcttatcaat gttgtttaaa
    23221 gttcccttta ggtggtggat cagcattgca atgacgactt cgtcgtacat tgtatataat
    23281 tacttaaaga aaaagagaga aaaggaatga tcttatacca gatcattcct tttctgcttt
    23341 ctgtaaatcc ctcggagtgt gtttggcgct ttgatacgaa gtgtcaaagc tgtataaacg
    23401 ttactatttc caaaaaagta acagaaaatt cctgctttgt aggactgctt tgggtgagta
    23461 atagacatgt cgactcaccc tatctcctga tggcgaaaag aatttagcaa tggtgcaagt
    23521 tgttctgaac tcgagaaaaa acatgccgaa atcgaagaaa agcgtgcaga acttgaagcg
    23581 aagaagcaag aaatgttgaa tcgcttggat aaatagaatt tagaaaacag aaaaaactaa
    23641 aaagaatgta gggtttattt ccctacattc ttaaaataac ttagtacata aatgacaatg
    23701 ctgccactgc cgtcaatatt gcaaaaacta ttttccaaat ttttttattt tttccaaaaa
    23761 tcttatcagg taacaagctt attacaagaa aggtaataaa caacaccaat ttaagtgtgt
    23821 atatcataaa aacaccttct ttcctacaat tatattataa tactttatgt aagcgaatac
    23881 aagagatgtg aggtaaccaa ctacgaaaaa atataaggct gaagacagta aaaaccagca
    23941 tttaaagcct tcactgtatc taggatttcc ctatttttag acaagattga cccaaatcca
    24001 cagcatttaa aaaagcgaat ttcaatcgaa actcgctttt ttacaaaatg tattagtata
    24061 aatttgtatc ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg
    24121 ctcaaagcac cgctttgagg ttgcagataa agctgacgtg gtttgaagag attttcgaag
    24181 agtattagtt caagtgccag atgtcttcat tatactgagc gattgtacgg tcagatgaga
    24241 agaatcctgc tttagaaatg ttaacgatga ctttatccaa ccatgcgtca cggtcttcgt
    24301 agtcagcaag catttgctct ttgactttga tgtagtcttc caagtcaaga agagtcatga
    24361 accagtcttt gttgatcaat tcattgtaaa gacgttccaa gcgctctttg tttccagctg
    24421 caagaactgc atcactaacg atgaagtcaa ccaatggttt gatagcttca cgagcgtaga
    24481 attcgcttga tttgtaagct gcttttgcgt aaaggtcgat aacagtttct gaatcttcac
    24541 cgaagatgta gatgttttct tctccaacca actcagcgat ttccacgtta gcaccgtcca
    24601 tagtaccaag tgtcaaagct ccgttcaaca tgaatttcat gttaccagta cctgaagctt
    24661 ctttagaagc aagtgaaatt tgttctgaga tatcacatgc tgggataagg aaacttgctg
    24721 cagtaacgtt gtagttttca accataacta cttgcaagtg tggagctact gctggatcgt
    24781 tagcaataac ttctgacatg caaaggatta aatggataat gtcttgagcg attgtgtagg
    24841 ctggagctgc tttaccacca aagaagattg tgatgggacg agcagggatg ttaccagctt
    24901 tgatgtcaag gtatttgtgg atcacgtaca aagcgttcat ttgttggcgt ttgtactcgt
    24961 gaagacgttt gatttggata tcaaagatag aatttggatt gatttccaca ccttggtgtt
    25021 ctttcaagtg acgagccaat ttacgtttgt tgtgagcctt gatgctttcc aatttttctt
    25081 tgacagctgc tttgtcttca taagacaaca gtttttcaag ctcatctgct tcatggtgcc
    25141 aaccatctcc aagaatctca tctaagtagt gagacaatct tgggttagca tgcataagcc
    25201 aacgacggaa agtgataccg tttgttttgt tgttgaactt ttctgggtaa aggtcgtaga
    25261 aggctttcaa ctcagaattt ttcaagattt cagtatggag tgctgcaacc ccgttaacac
    25321 tgtatccgta gtggatatcc atgtgagcca tgtgaacacg tccgctctca tcgatgattt
    25381 gaacagctgg atctttgtac tctgccttca cacgacggtc caattcttcg atgattggta
    25441 ccaagtgagg aaccacttct tgcaagaatt caagaggcca tttttcaagc gcttcagcaa
    25501 ggattgtgtg gttagtgtag gcagtcatgc tacgaacaat tgagattgct tcgtcaagct
    25561 cgataccacg tgcagttaaa agacgaatca attcaggaat caccattgat gggtgagtat
    25621 cgttgatttg gacaactgcg tagtcagcaa ggtcatgcaa gttgcttcct ttttcgattg
    25681 cttcgtcgat gatcaattgc gcaccgtttg aaaccatgaa gtattgttgg aagatacgga
    25741 gcaattcacc ttgacggtca ctatcatctg ggtaaaggaa gagagtcaag ttgcgagcga
    25801 tatctgtctt gtcaaagttg ataccatctt taataataga agaatcaact gaatccaagt
    25861 caaacaaacg caagcggttt ttagtcgctg tttcataacc agtaacatca atatcgtaaa
    25921 gagttgatgt caaagtaaag tctgcaaatg gtacttggta gctacggctt gagcaaacca
    25981 accagttttg ctctgtcaac catgcatttg gaattgtttc ttgttggttg tttttaagaa
    26041 cttgttggaa aagaccaaag tggtagttaa gaccaacacc gtcaccattc aaaccaagag
    26101 tagcaattga gtcgataaag caggcagcca aacgtcccaa accaccatta ccaagagatg
    26161 gttccaattc aacttcttca acttcgatca agtctttacc tgcagctgca agttcttttt
    26221 taacatcgtc gtaaagacca aggttaatca agttgtttga caagagttta ccaatcaaga
    26281 actcagctga gatgtagtaa acttttttct taccagtgtt gactggtttt tggctgcttg
    26341 caagcttgct gtagttaaga agagcaaggt aaagctcttc attgctacat tctgcaatgg
    26401 ttttattgta acgattttgt acaaattctt gtagtgataa catgtttagt tgtctcctga
    26461 ttattgtctt atttctttaa atctaccaaa ttttcattaa ttcggcgata aattgttgtc
    26521 aagtcaagca aaccttcctc gacagctggt gtcaattgat cttcagtcat acgccaagac
    26581 cagtttccac caagggtaga tgggaagttc atacgagctg cctcatccaa ttctagtaaa
    26641 tcttgcatag ttgcaattgc cataaagcta actgatgaaa atactgtacg aagcatagcg
    26701 tgtaccactg tttcgtattc tttacggttc gtgtaacgag ccatgtactc acgagtcgca
    26761 tcatcaatct cattacggta ccaaccaaga accgtattgt tatcgtgtgt tcctgtgtac
    26821 ataactgagt tagcaggtgc caagtgtggg ctatcaatgc tttcgtcttc tgggttgaag
    26881 gcaaattgaa gaatcttcat tcctgggaag ccagtacgtt cacgcaattc gatcacttca
    26941 tctgtcatga agccaaggtc ttctgcgatg atgtttagct caccaagttc ttccttaacg
    27001 gctgcaaaaa gcttgtagcc tggacctttc acccactcac caggtgctgc tgtatcggaa
    27061 ccagcaggga tttcccagta agattcgaag ccacggaagt ggtcgatacg aacgatatcg
    27121 tagattttga agctttcacg caagcgttca atccaccatt tgtagccgtc tttgtccatt
    27181 gcttcccagt catagattgg gttaccccaa agctgaccag ttacagaaaa ctcatctggt
    27241 gggcatcctg cgatacaagt agccttacca ttgacatctg ttttgaagag atgtggattt
    27301 gcccacatat cacttgaatc ttccgctacg tagattggca tgtccccaac gatttcgatg
    27361 tggttgtcgt tagcgtaagc tttcaatttc aaccattgtt ggaagaagaa gtattgagtc
    27421 acacggtggt aaaccaactt gtctgccaat tgctcacgat agctttcaag tgctgaagct
    27481 ttacgagcac gagcatctgc atctggccat tcagtccaag caagattgtc aaaatactct
    27541 ttgatagcca tatactcagc aaagagctca agccatgatt ggttgtcttg agcaaatttc
    27601 tcaaaatctt taacatctcc gacttcaaag aaacgtttca ccgctttttc taaaagagga
    27661 cgacgtgcat agtagatttt agcatagtca acttcagacg catcgctacc aaagtcaact
    27721 ccttcaaggt cacttgcttc caacaaacct tgctccacca agatatctaa atcgataaaa
    27781 tgagtgtttc ctgcgaaggc tgagaaagat tggtaaggag aatccccgta actagttgct
    27841 cctaatggaa ggatttgcca gtaacgttgt tttgtacgga ccaagaaatc aacgaagtcg
    27901 taagcacttt gaccaaatga tccgattccg taagctcctg gaagagaaga gatgtgcatc
    27961 aacacaccac tttgacgttt tttcataata gcacctcgtg tgttaaaata atggaacgtt
    28021 gcgtattttg cagacgcaaa cgtttgcgtt acttataagt atactccttt tcaagcataa
    28081 ttgcaagcgt ttttaaaaaa cttttttgat tatttttaag gagactaact cattttagca
    28141 aagataactt aaaactatct aatcctaagg tttgactctc acgagacagt ctacaaagta
    28201 caaaacctcc ttagggagct tgaatttata tgtaacaaag cacaaacgtc catagaaaat
    28261 agatagggat tagaaccagg gaggtagccc ctcctggttt ccctctttag acagattcca
    28321 tatattttta ttaaaaatac tgtattctta tctatttcat acttttcttc tattaaaatg
    28381 caaaattatg ctatcaaatc aagcttaaaa attttttaaa atttttacaa aaaatacttg
    28441 caaccgtttt ctatttgtgc tatactaagc tcataaagga aaacgtttgc gtttccttat
    28501 caataaaact tgctattctt tgggaggaat acactatgtc atctaaattt atgaagagca
    28561 ctgcggtgct tggaactgtt acacttgcta gcttgctttt ggtagcttgc ggaagcaaaa
    28621 ctgctgataa gcctgctgat tctggttcat ctgaagtcaa agaactcact gtatatgtag
    28681 acgagggata taagagctat attgaagagg ttgctaaagc ttatgaaaaa gaagctggag
    28741 taaaagtcac tcttaaaact ggtgatgctc taggaggtct tgataaactt tctcttgaca
    28801 accaatctgg taatgtccct gatgttatga tggctccata cgaccgtgta ggtagccttg
    28861 gttctgacgg acaactttca gaagtgaaat tgagcgatgg tgctaaaaca gacgacacaa
    28921 ctaaatctct tgtaacagct gctaatggta aagtttacgg tgctcctgcc gttatcgagt
    28981 cacttgttat gtactacaac aaagacttgg tgaaagatgc tccaaaaaca tttgctgact
    29041 tggaaaacct tgctaaagat agcaaatacg cattcgctgg tgaagatggt aaaactactg
    29101 ccttcctagc tgactggaca aacttctact atacatatgg acttcttgcc ggtaacggtg
    29161 cttacgtctt tggccaaaac ggtaaagacg ctaaagacat cggtcttgca aacgacggtt
    29221 ctatcgtagg tatcaactac gctaaatctt ggtacgaaaa atggcctaaa ggtatgcaag
    29281 atacagaagg tgctggaaac ttaatccaaa ctcaattcca agaaggtaaa acagctgcta
    29341 tcatcgacgg accttggaaa gctcaagcct ttaaagatgc taaagtaaac tacggagttg
    29401 caactatccc aactcttcca aatggaaaag aatatgctgc attcggtggt ggtaaagctt
    29461 gggtcattcc tcaagccgtt aagaaccttg aagcttctca aaaatttgta gacttccttg
    29521 ttgcaactga acaacaaaaa gtattatatg ataagactaa cgaaatccca gctaatactg
    29581 aggctcgttc atacgctgaa ggtaaaaacg atgagttgac aacagctgtt atcaaacagt
    29641 tcaagaacac tcaaccactg ccaaacatct ctcaaatgtc tgcagtttgg gatccagcga
    29701 aaaatatgct ctttgatgct gtaagtggtc aaaaagatgc taaaacagct gctaacgatg
    29761 ctgtaacatt gatcaaagaa acaatcaaac aaaaatttgg tgaataaaaa atttgttcaa
    29821 ggggggtgga aatcaaatcc ccctttgaat ttatcaatag agacacaaat aatttagctt
    29881 tcttataaaa aagtagtatc ctatgaaagg agttaatatg gaaaagcaac aacctagtaa
    29941 agcagccctg ctgtctatca ttcctgggtt aggacagatt tacaataaac aaaaagccaa
    30001 aggttttatc ttccttggtg taaccatcgt atttgtcctt tacttcctag cacttgcaac
    30061 ccctgaattg agcaacctca tcactcttgg tgacaaacca ggtcgtgata attccctctt
    30121 tatgctgatt cgtggtgcct tccatctaat ctttgtaatc gtttatgtac tcttttattt
    30181 ctcaaatatc aaagatgcac atacgattgc aaaacgcatt aacaatggaa ttccagttcc
    30241 acgcacactc aaagacatga tcaaagggat ttatgaaaat ggcttccctt acctcttgat
    30301 cattccatct tatgttgcca tgaccttcgc gattatcttc ccagttatcg taaccttgat
    30361 gatcgccttt accaactacg acttccaaca cttgccacca aacaagttgt tggactgggt
    30421 tggtttgacc aactttacaa acatttggag cttgagtacc ttccgttctg cctttggttc
    30481 tgttctttct tggactatca tttgggcttt ggcagcttct actttacaaa tcgtaattgg
    30541 tatcttcaca gctatcattg ccaaccaacc atttatcaaa ggaaaacgta tctttggtgt
    30601 tattttcctt cttccttggg ctgtcccagc cttcatcact atcttgacat tctcaaacat
    30661 gtttaacgat agtgtcggtg ctatcaacac tcaagtattg ccaatcttgg ctaaattcct
    30721 tcctttcctt gatggagctc ttattccttg gaaaacagac ccaacttgga ctaagattgc
    30781 cttgattatg atgcaaggtt ggctcggatt cccatacatc tacgttttga ctttgggtat
    30841 cttgcaatct attcctaacg acctttacga agcagcttat attgacggtg ccaacgcttg
    30901 gcaaaaattc cgcaacatca ctttcccaat gattttggct gttgcggcac ctactttgat
    30961 tagccaatac accttcaact ttaacaactt ctctatcatg tacctcttca atggtggagg
    31021 acctggtagt gtcggaggtg gagctggttc aaccgatatc ttgatctcat ggatctaccg
    31081 tttgacaaca ggtacatctc ctcaatactc aatggcggca gctgttacct tgattatctc
    31141 tatcattgtc atctcaatct ctatgatcgc attcaagaaa ctacacgcat ttgatatgga
    31201 ggacgtctaa gatgaataac tcaattaaac tcaaacgtag actgactcaa agccttactt
    31261 acctttacct gattggtcta tcaattgtaa ttatctatcc actgttgatt accattatgt
    31321 cagcctttaa agcaggtaac gtctcagcct ttaaactaga tactaatatc gacctcaatt
    31381 ttgataactt taaaggcctc ttcactgaaa ccttgtacgg tacttggtac ctcaacactt
    31441 tgattatcgc cttaattacc atggctgttc aaacaagtat catcgtactt gctggttatg
    31501 cttacagccg ttacaacttc ttggctcgta aacaaagttt ggtcttcttc ttgatcatcc
    31561 aaatggtgcc aactatggcc gctttgacag ccttcttcgt tatggcgctt atgttgaacg
    31621 cccttaacca caactggttc ctcatcttcc tctacgttgg tggtggtatc ccgatgaatg
    31681 cttggctcat gaaaggctac ttcgatacag tgccaatgtc tttagacgaa tctgcaaaac
    31741 tagacggtgc aggacacttc cgccgcttct ggcaaattgt tcttccactt gttcgcccaa
    31801 tggttgccgt acaagctctc tgggccttca tgggaccttt cggggactac atcctctcta
    31861 gtttcttgct tcgtgagaaa gaatacttta ctgttgccgt aggtctccaa accttcgtta
    31921 acaatgcgaa aaacttgaag attgcctact tctcagcagg tgctatcctc atcgcccttc
    31981 caatctgtat tctcttcttc ttcctacaaa agaactttgt ttcaggactt acaagtggtg
    32041 gcgacaaggg ataatttatc cccgccaccc tttttcattt tatactcttc gaaaatctct
    32101 tcaaaccacg tcagctttat ctccaacctc aaagttgtgc tttgagcaac ctgcagctag
    32161 cttcctggtt tgcactttga ttttcattga ctattagcga ttgtcactgt aaataatatc
    32221 cttgtagcaa gcaatttttc tcctagactt gaaataaagc gcatttctct atataataat
    32281 actcatatag aaaacacctt ttagaaagat acctatgctt ccatatccat tttcctattt
    32341 ttcaagtatt tgggggtttc gtaagcccct gtccaaacgt ttcgagctca actggtttca
    32401 acttctcttt accagtatct tccttatcag cttgtctatg gtacccattg ctatccaaaa
    32461 cagctcccag gagacctatc cgctagaaac ttttatcgat aatgtctatg aacctctgac
    32521 agataaggtt gtccaggatc tctctgaaca tgctacaatt gtcgatggca cattaactta
    32581 tactggaaca gctagtcaag ccccttctgt tgtgattggt ccaagtcaaa tcaaggaatt
    32641 acctaaggac ttgcaactgc atttcgatac aaatgagcta gtcatcagca aggaaagcaa
    32701 ggaactgacc cgcatctctt accgagccat tcagactgag agtttcaaaa gcaaagacag
    32761 cttgacccaa gcaatttcta aagactggta ccaacaaaat cgtgtctata tcagcctctt
    32821 cctagttctc ggtgcgagct tcctctttgg tttgaatttc tttatcgtct ctctaggagc
    32881 tagtcttctc ctttatatca ctaagaaatc acgcctcttt tcatttagaa cctttaaaga
    32941 gtgctatcac tttatcttga actgtttagg attgccgact ctgattacac ttattttggg
    33001 attatttggc caaaatatga caaccctgat tactgtacaa aatattcttt ttgttctgta
    33061 tctggtcact atcttttata aaacacattt ccgtgatcca aattaccata aataggagat
    33121 ttttatgccc gttacgatta aagacgtggc caaggctgct ggtgtttcgc cttcaaccgt
    33181 aacccgtgtt attcaaaata aatcaaccat tagcgacgaa acaaaaaaac gcgttcgcaa
    33241 agctatgaag gaactcaact accacccaaa cctcaacgct cgtagcttgg taagcagcta
    33301 tactcaggtt atcggattag ttcttcctga tgactcagac gccttctacc agaatccttt
    33361 ctttccatcg gttctacgtg gcatctctca agtcgcatct gaaaaccact atgccattca
    33421 gatagcaaca gggaaagatg agaaggagcg tctcaacgct atttcacaaa tggtctacgg
    33481 caagcgtgta gatgggctaa tctttctcta tgcccaagaa gaagaccctc tcgtaaaact
    33541 cgtcgcagaa gaacagttcc ccttccttat cttaggtaaa tctctatctc ctttcatccc
    33601 acttgtcgac aacgacaatg ttcaagctgg ttttgatgcg actgaatatt tcatcaaaaa
    33661 aggctgcaaa cgcattgcct ttatcggagg aagtaaaaag ctcttcgtga ccaaagatcg
    33721 tttaacaggc tatgaacagg cgcttaaaca ttacaaactt accactgaca acaatcgcat
    33781 ctactttgcc gacgagtttc tggaagaaaa gggctataaa tttagcaagc gattattcaa
    33841 gcacgatcca caaattgatg ctatcatcac aaccgatagc ctcctagctg aaggtgtttg
    33901 taactatatt gccaaacacc agctggatgt ccctgttctc agctttgact cggttaatcc
    33961 caagctcaac ttggcagcct atgtcgatat caatagttta gagcttggtc gtgtttccct
    34021 tgaaactatt ctccagatta ttaatgataa taaaaacaat aaacaaattt gttaccgtca
    34081 attgatcgcc cacaaaatta tcgaaaaata agagactggg caaaaagtcg ttaaaagcaa
    34141 aaacgcatag tatcaggtat tgaaaaaact tgatactatg cgttttaatg tgggaagatt
    34201 tacttccttt tctactgaaa ttgagtcttt tcccaagatc tttttatact caatgaaaat
    34261 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cactgttttg aggttgtgga
    34321 tagaactgac gaagtcagct caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt
    34381 cagctcaaaa catggttttg aggttgcaga tagaattgac gaagtcagta acatatatac
    34441 ggcaaggcga cgctgacgtg gtttgaagag attttcgaag agtattaatc actaattatc
    34501 tatctcaaca aatcttccta gaatatgaac attttccgag acagagacaa aggagcttgg
    34561 atccacttgt gtcataatct gtttaaattc attaaactct gcacgtgtaa tgacagtgat
    34621 taaaactgcc tttctctcgt gattataggt tccttctgca tcgtggatca tggttgctcc
    34681 gcggtgcaat tttttatgga ttttttcaat taccttctct ggatgatttg tcacaatcat
    34741 ggcctgcata cgcttttgct tagtaaagac tgcgtctgtc acacggctag agacaaagat
    34801 ggtaatcata gaataaagag cgtatttcca accaaaggtc aaacctgcta tcagcatgat
    34861 agttccattt accaagaaag aaatactacc gacattctta cccgttttct tacgaatagt
    34921 caggctgacg atgtccgtcc caccactgga gatattgttt cgaagagcaa aaccaatccc
    34981 caaacccata acaacacccc caaaaagggc attgataatg ggatcctctg tcaaggttgc
    35041 cacagggaca aactggataa agaaggaact catagatacc gtgataaagg taaagacggt
    35101 gaacttatgg ccaatctgat accaagctaa gaccatcaaa gggaagttaa tggcgtaaaa
    35161 gcttagcgaa atcggaatat gaaaaccaaa ccagtgatta ctcaaggcag agataatctg
    35221 tgccagacct gttgcaccac tcgaatacac atgccctggt tggaaaaaga aattaactgc
    35281 tactgctgat aaaaaaccat agaccagaga ggccgaaatc ttctcatcat acttttctcg
    35341 agagatactt tgtaagacac gtaaaatttt tatctgataa gcaaagcggc gcagataata
    35401 gcgccaccgc ttaattcgtt ttgtttgttt catcttcttc tacttgtaag ctgagttcct
    35461 ctagttgttt gagagcgact gttgatggag cttgtgtcat tgggtcagtt gccttgttgt
    35521 tcttaggaaa ggcaatgact tcacggatat tttcttctcc agcaagcaac atgacaaaac
    35581 ggtcaagccc gatagccaaa ccaccgtgtg gtgggaaacc atagtccatg gcttcaagaa
    35641 ggaaaccaaa ctggtcattg gcttcttcag ttgagaaacc aagagccttg aacatgcgtt
    35701 cttgaaggtc tttttggttg atacgaaggc taccaccacc aagctcataa ccgttcaaga
    35761 cgatatcgta agcaatggca cgaaccttag ccaaatcacc ttctaattcg tgagcagtct
    35821 cttcctgtgg aagtgtgaaa ggatggtggg cgctcatgta gcggccttct tcttcagacc
    35881 attcaaacat cggccagtca accacccaaa ggaagttgaa cttatcatta tcaatcaagc
    35941 caagctcttt agcaatacgt ccacgaaggg cacccagtgt tgcattagcc acttcaagcg
    36001 tatccgccac aaagagaacc aagtccttat cttcaagaac aagcgctgtt gtcaattctt
    36061 cttggatacc agtcaagaac ttggcaactg gtccgtttaa ttctccatca accaccttga
    36121 cccaagcaag acctttggca ccatactgtt tggctacttc cgtcatcttg tcgatgtctt
    36181 tacgtgaata gttgtccgca gctcctttga ccacaatcgc ttttacagca ggtgcttctg
    36241 aaaagacttt aaagtctaca cctttgacca cttctgtcaa gtcctgaagc aacatgtcaa
    36301 aacgagtatc tggcttgtca gaaccgtaaa gagccatagc atcatcgtat ttcatacgag
    36361 ggaacggtag cgttacttcg atgccttttg tttccttcat cacgcgcgcg atcaagcctt
    36421 ctgtaatatc ttggatttct ttctcagtaa ggaaggacgt ttccaagtcg acctgagtaa
    36481 attcaggctg gcggtctcca cgcaagtcct cgtcacggaa acatttaacg atttggtagt
    36541 aacggtcaaa accagcattc atcaagagct gtttcgtgat ttgtggactt tgaggaagag
    36601 cgtaaaaatg ccccttatta acacgagacg gcactaaata atcacgcgcc ccttcaggcg
    36661 ttgacttaga aaggaatggt gtctccacgt cgataaactc caactcatcc aaatagttgc
    36721 ggatagagtg ggtcaccttg gcacgaagtt taagattttc caacatttct ggacgacgaa
    36781 ggtcaaggta acggtaacgc aaacgtgtat cgtcatttgc ctcaatgcca tccttaatct
    36841 caaatggtgt tgtcttagct gtgttaagca caataagagc tgtcacgttt aactcaaccg
    36901 caccagttgg caacttatca ttggcttgct cacgcgcagc gacctgacca gtcacctcaa
    36961 taacaaattc gctacgaagg ctttcagctg ttgccataac ctctgcagat actttttcag
    37021 ggttgataac caactgcatg attccttcac ggtcacgaag atcgataaag atcaaaccac
    37081 caaggtcacg acgacggcca acccatcctt tcaaggttat ttcttgtccg atgtgttcct
    37141 cacgaacacg accagcatac atactacgtt tcattatttc tctcctcttt tattctgtta
    37201 ctattttacc ataaaagcgc aggctcttca tgaaaatcat cagaaaagtt tgccagtctt
    37261 taaaagtcag gtgaaagccc taaaaattag cgctaatgct cttcgaaaat ctcttcaaac
    37321 cacgtcagcg tcgccttacc gtaggtatgg ttactgactt cgtcagtttc atctacaacc
    37381 tcaaaaccat gttttgagct gacttcgtca gtttcatcta caacctcaaa accatgtttt
    37441 gagcaacctg cggctagctt cctagtttac tctttgattt tcattgagta taatacaaaa
    37501 atccgatgaa cttcaccgga ctcttttatt ttgaattttt gcctgcttta cgcttttcag
    37561 cgatttcggc tgcctttcga ggcaagacaa tttccgttat gtaagccgtc ccaaaacgca
    37621 gtacacctgc aataggagca aagacaactg ctagatagtt atagaagaaa tcgcctttga
    37681 aggcataagc tagcgctcca atgatgaaaa atagaacgac tgcctgaatc actgctacta
    37741 aaattactcg tttcatgtga cctcctgact ctattatagc atgagaatca tcaaaaagcc
    37801 gactaaatta ttcaaagcgt gaagagaaat actgtagacc agaccttttc tgctaatgta
    37861 agccaaaccc aaactaaaac caaggctaaa atagacaaaa aattgttgca catcacctgg
    37921 aaaatgaatc aaggcaaata gaagactaga taccagaaga aaaatcaggg ttcgtttact
    37981 attgtcctgc ttaggaaaga gatagcgtgc taacatccct ctaaaaacaa tctcttccgt
    38041 caaaggagca aaaataacca cagcaaagaa tgagaaaagt ggttgagaca aggtcaagtc
    38101 tgtcgctatt tgttgattta ctgaaggatc atctggcaag aagaattgaa cgaccagaga
    38161 taagaaccaa accaagacag gaagccaaat aaatcgatta aagccgctct tctcaatatg
    38221 aacaggagcc ttctgatacc atttgtaaat gccgtacaca tatactccag ccaaggccac
    38281 atagagtaga gtaacagcat agggtgaagc gcctaaagca agcgacgcag tcgcgagccc
    38341 ctgaataaag ccatagataa ataaaaagga tagaagggct agaagaatcc agccaaggtt
    38401 tttaagtaat ttcatagata actcctttat ttgaaataac gttttaccat aggtaactgc
    38461 atcacattga tataaacatg gatggctcct acaagcaaga aagctagtaa ctgaatctct
    38521 cctgtcaaga aagaaatgat aataagaaaa atatataagg ctggtaagac atattggtgt
    38581 aattggaata aaattcgaaa actctgttcc aaattagcct gacgctcccc ttcatcataa
    38641 gaatttatat agttcaagac atcctttggt gtagcgaaaa attccaaatc aaactgacga
    38701 acaatcgcaa tggttttaaa aagagatttt tgagcgacta agaataccac aaagagtaag
    38761 aaagaaagga aaaatgtttg agggtttgta tgcaatataa tcacctcact taatgaaata
    38821 aaaatagcca atggaatcgc tacacctgta atattaaaag caatggttcc aaactcaaga
    38881 ttccgataca tttgcacata ataggtttca ttcagatcgt catccatttc ctcttgatac
    38941 aaggaatgaa attttctgct tttctttaag aaattgaaag tcaaaaacat actaatgaaa
    39001 cctatcagta aacaaatagc tgatatccat ggcatcaagg cttttacatc taaaataatt
    39061 tcgtgggatt cgacacgtgc cttaaacatc cctacaaaca tgcccaagaa cccccccaag
    39121 acaatagaca tcaaaaataa caatctacgt ttctttttca tattcattct cctttttcac
    39181 ttgctagatt tttggatttc ttttcaatcc attcagttac tgggatgaga gcaaagtaga
    39241 cccaaacaaa ttggtcgctt tgatagggat taaaccagct taggtccatc ccaatcagta
    39301 gaaatacgct gactaataaa gctatgacca ctacataata aatcacttta tacttgttca
    39361 tcactcgtcc tcctccaaac gaaataccga ttcgactgtt tcgttgaaaa tttgagatat
    39421 tttcagggca atgataatgg atggggtgta ctcatcccgt tctagtaggc taatggtctg
    39481 tctggaaacc cctgccagtt tggctaggtc ggtttgattg agaccatcgc gagctcgaag
    39541 ctcttttaga cgatttttta gttgcacgtt acacacctac tctccgtcaa attcaacggt
    39601 ttggatatct tcaatacgtt gcaacttgaa tttttctttt cccgtattat caacactacg
    39661 tagtttgacc cattcctcat caacatccac aacttcccag ttatctggcc caatatacac
    39721 tcccgttata attggttcct ttccaatcat ttcttgtaat aatctcgaca tttctgcgtt
    39781 tcctttctct tttcgctcaa gttttttgat tttattctct agtttcttga tttttttaga
    39841 attattagaa taaaagaaaa tcataaatag tataaatcct agtacccaca ttataactcc
    39901 tttctgcttc ctatttctta acttgaattc attgtaacat atctttttct ttttgacaat
    39961 tatagttgtc aaaaagttta tgatttttgt cattttgcaa aagaaaaagg tcaggagtaa
    40021 gttcctgacc actttatcta tcattaatac tcttctaaaa tctcttcaaa ccacgtcagc
    40081 ttcaccttgc cgtaggtatg gttactgact tcgtcagttt catctacaac ctcaaaacca
    40141 tgttttgagc tgacttcgtc agttctatcc ataacttcaa aacagtgttt tgagcaatct
    40201 gcggctagct tcctagtttg ctctttgatt tttattgagt ataaaatcct agtttttcaa
    40261 agatttctga aaagttttgg ctgattgtct caagtgacac ttgcacttct tctcgggttt
    40321 ggttgttctt gaccgtcact tgtccgcttt cgacttcgct ctctcccagg gtgatgaggg
    40381 tcttagtcgc aaagacatcg gctgacttga actgagcttt gagcttacgg ttgaggtaat
    40441 cacgctctgc tttgaaacct tgttggcgaa gggcttggac tagttctagg gctttgacat
    40501 ttgctccatc acccaagact gcgatataga catctagggc attttcgata gggagggcca
    40561 cgccttgttt ttcaaggatg agaagcagac gctctacacc aagcccaaaa ccaaatccag
    40621 cagtttcagg gcctccaaag taagcaacca aaccatcgta gcgaccaccc gcacagactg
    40681 tcaagtcatt gccctcaatc tctgtgataa actcgaaaat ggtgtggttg tagtagtcca
    40741 gaccacgcac catattggta tcgatgatgt aatctactcc aagattttcc aacatctgac
    40801 gcacagcatc aaaatgagct tggctttctt catcaagaaa gtccaagata gacggcgcat
    40861 tctctactgc caccttgtct tctttttcct tagagtccaa gacacgaaga ggattttcct
    40921 ccaagcgacg ttggctatcc ttagacaagg tctccttgag cggtgtcaaa tagtcaatca
    40981 aggcttggcg gtaggctgca cggctctcag gatttccaag agtgttgagg tgcaatttga
    41041 caccttgaat accgatttcc ttcaaaaaat gggctgccat aacgattgtt tccacatcgg
    41101 tagctggatt gctagagcca aaacactcaa caccaatctg gtggaattgg cgcaagcgcc
    41161 ctgcctgtgg acgctcataa cggaacatag gtcccatata gtagaacttg cttggctttt
    41221 gcacttctgg ggcgaagagt ttattttcca cataggaacg gacaacgggc gcagttcctt
    41281 ctggacggag ggtaatatga cggtcaccct tgtcataaaa atcgtacatt tccttggtta
    41341 cgatatccgt tgtatctccg acagagcggc tgataacctc gtaatgctca aaaataggcg
    41401 tgcgcacttc tgcatagtta tagcgcttga aaatctcacg ggcaaagccc tcaacgtact
    41461 gccacttagc agactcagca ggtaaaatat cctgcgttcc ttttggtttt tgtaatttca
    41521 tagggaatcc tctttaaact taatagtctt attttaccat aaatagaggg attaaaacag
    41581 taagaaaaaa attaggattt agatatcatt tttgagatta agaattgtta aaaaaatagc
    41641 tagcaaggaa agaccaacaa atagcatcca agtcaactgc atgttccata cggctactag
    41701 tgaaaaacaa gctgttccca caggtatgga taaggtaaac aatagaccta aaaaattact
    41761 agtacgagct agaacctctg gagctagatt tttcatgagc atggcactaa tctttggttg
    41821 aactttacca gacacataca gagtaaagaa gagaaatagc aaaccaagca cgacttgatt
    41881 gaataaatta gccaaaccaa ctagactaag tcctacggtc gcccacatca tcaatctagg
    41941 caaggactgc ttcccaaaat aatcattgcc cgtaaggcta ctgatgatga ttgctactaa
    42001 aacacagaat tgattgataa atagtgcctc tgtataagaa aaattcaaga gagaatggct
    42061 caaaaagaag atattataaa ttccacccaa agcgctaccc aaggaattaa taagcaagac
    42121 agcaaagagc ataaaaccaa agtttttctg tccactttta agaaaaacga gacgtaaatt
    42181 tcggtaaatt gttaggaact ggtctttgat agaaagcttc tcatttttta agttttcacc
    42241 atcagcagat gacattgaca ggctcaattt gctttttcct aaaaagagga tagtggctga
    42301 tactaggaaa aagcaggcat tgattcccgc aacgagagaa aaattgttga ccgatagagc
    42361 taagagccag actccgaaag cttgaccacc aatagctgaa atataggtga tgaactgtga
    42421 aaaagaataa gcctccatca gatcatcttc agctactttt tccttaataa gaggcatacg
    42481 caggccacct gcaaaatcac tgatgatatc actaatgaca ttgatcaaac acaggctaga
    42541 aaaggcaaag agactagctt gctgaacaac tagggctgct agaaaaaata gaaccgcctg
    42601 aaacaaaccg ctatagacca tccatttgac cttgtccctc gtgtaatctg cccgaatccc
    42661 tgcaaaaact gtaaagaagg tcggaagaat catgacaata ttcgccatag caacagcaaa
    42721 agatgcttgt gacaaggtcg atgcatagac gataaagacc aggttgaaaa tcgaagcacc
    42781 aaaagcattg aagaagcgtg ataaagtcaa aattctataa gctggatttc taaacaatag
    42841 tttcatagat aatctccctc cttgttctaa gttctacatc aagaatagct ttagtatagc
    42901 acttagaaat ttgagaggga gaactcttga atatatgcaa caaataaaat gagcaaaaag
    42961 aaacgataga acttttgtaa tgacctgaga gagggcaata gttctatcgc ttcaaatttt
    43021 ttcttggttt gcagatattc aacattcggt cgtatttcta tagtattcgg cagatttatt
    43081 acagccaagc atctcaaaaa tacggacagc atcctacatc tttttctggc cttccttgac
    43141 tctaccttgc ttgctatcaa ggagaccttc tgcccacaga taaacaattc ggaaataggt
    43201 ctcattttcc ttgtagaaat gctcttcgat aacacgttta aaataatagg cattggtaaa
    43261 tttttcacac tcaatactag ctaaaaagcc attcaatagt atagtatgaa aaaagtttcg
    43321 attaccagac atttccatta gaaaatcaga tttacgtacc atttctcgta catatctagt
    43381 aaaaagagaa acagataaaa atggagaact gactgaaaat aaattgagtt catagattcc
    43441 ccagatctcg gtagaaaaca aataatcatg aaggactttt ccttcctctg ctgttaactc
    43501 taccctttca tctatgctct tcatataaga cttgataata atggcattta gaatatgttt
    43561 ctgtttgttg tgagaatggg catgcttttg atactccctg cgatataagt cctcaagagg
    43621 tgctatattc tttggttcca agacatctgt aatttctttt ctcaactcag aatctgtatc
    43681 atactggaaa cctctcgcca gaaagaggat ctcctccaca ctggcagata tattttccag
    43741 agcaaataga aacttttcca ccaaaagctc actctgacct gtttcaaaac gggacaacat
    43801 agacggcgaa aattgtcctc cggttgcttg tctcagtgag atatttcttg actctcgtaa
    43861 ttgtctaaag acttttccaa tctgctccat agacttcccc ttgattccgt attttcttca
    43921 ttttatcata tttttcagaa aattcatcaa aaacttgcca aattgtcaga attatgagaa
    43981 aatagaggat atttatcacg tggagggact gctatgagag acgatatcaa aatcaatgac
    44041 cgtgctttgg ccttgcaaga ccaaatcatc gaaaaactag agaaagtttt tgatacagat
    44101 gtggaattgg atgtttacaa tctaggtctg atttatgaaa tcaatctgga tgaaacgggg
    44161 ctctgcaaga ttgtcatgac cttcaccgat actgcctgtg attgcgccga aagcctgcct
    44221 attgaaatcg tggcaggtct gaaacaaatc gagggtatca aagatatcaa ggttgaagtt
    44281 acctggtcgc ctgcttggaa aatcacacga atcagtcgct atggccgtat tgcccttgga
    44341 ctaccacctc gttaagcagg ccaatcattt ttaaagatga aaaaagcaag ccaaaaatgg
    44401 cttgcttttt gatactcaat gaaaatcaaa gggcaaacta gaaaactagc cgcaggttgc
    44461 tcaaaacact gttttgaagt tatggataga actgacgaag tcagcccaaa acactgtttt
    44521 gaggttgtgg atagaactga cgaagtcagt aaccatacct acggcaaggc gacgttgacg
    44581 tgatttgaag agattttcaa gtatgagttt attttttacc tgacttgtcc atattccaga
    44641 agtctgtcac ggctccgcgt gaagcagatg atacgatatg ggcatattta ccgaggacac
    44701 cacggctgta aagtggtggc aaggttgttt ctgccttgcg tttttcaagt tcttcttcgg
    44761 atacggccat ggaaatttct ttggtatctt ggtcaaccgt aacgatatcg ccggtacgga
    44821 gataggcaat tggtccacca tcctgagctt caggagcgat atgtccaaca accagaccat
    44881 aagtaccacc agagaaacgt ccgtccgtca agagggccac cttatctccc tgacctttac
    44941 caacaatcat tgaagaaagt gacagcatct caggcatacc aggaccacct ttaggtccaa
    45001 caaaacgaac aacgactaca tcgccatcaa tgatttcatc tgtcaggacg gcctgaatcg
    45061 catcttcttc tgagtcaaag accttagctg gcccaacgtg acgacgcact ttaacacctg
    45121 ataccttggc aactgcaccg tcaggagcaa ggttcccgtt caagatgata agcggaccat
    45181 ccgcacgttt tggattttca agtggcatga taactttttg gcctggagtc aagtctgcaa
    45241 agtcagccaa gttttcagct acagtcttac cagtacatgt gatgcgatct ccgtgaagga
    45301 aaccatttgc caacaagtac ttcataaccg cagggacacc accgacttcg tagaggtctt
    45361 ggaagacata ctgaccagat ggtttcaagt cggccaagtg aggcacacgt tcttgaatcg
    45421 tattgaagtc ctcaagtgac aagtcaacat ttgcggcatg ggcaatggcg agcaagtgaa
    45481 gagtggcgtt tgtagaacca ccgagagcca tcgttacagt aatagcatct tcaaaggctt
    45541 cacgagtcaa gatatctgat ggtttgagac caagttccaa catcttaaca acagcacgtc
    45601 ctgctgcttc gatatcttct ttcttatcag ctgattcagc tgggtgagag gatgaccctg
    45661 gcaaactcat ccctagaact tcgatagcag ttgccatggt attagcagta tacataccac
    45721 cacaaccacc agggccaggg caggcattac attcaagacg tttcacgtcc tcagctgtca
    45781 tgtcaccgtg gttccatttt ccgatacctt caaagacaga aaccaagtcg atatctttac
    45841 catcaagatt tcccggtgca atagttccac cataggcgaa aatagctggg atatccatat
    45901 tagcaatagc aatcatagat ccaggcatgt tcttgtcaca gccaccgata gcgacgaagg
    45961 catccacgtt gtgaccactc atagccgcct cgatggagtc cgcgatgatg tcacgagatg
    46021 ttagagagaa acgcatacca ggcgttccca tagcgatccc gtccgctacg gtaatggttc
    46081 caaactgtac aggccaagcg cctgcagatt tgacaccttc tttagccagt ttcccgaaat
    46141 catgcaagtg aatgttacat ggtgtatttt ccgcccaagt cgaaatcact cccacaatcg
    46201 atgtttcaaa gtccttatct gtcataccag tcgcacgaag catagcacgg ttaggtgatt
    46261 taaccatgct gtcatagatg ctactgcggt gacgtttatc taattcagtc atcttatccc
    46321 tcccatttca gtttttacta ttatagcaca atttaaaggc aatgaacaga ataaaattct
    46381 tgaattttca gaaaattcta tacacatgtg aaatatttaa aattaaaaac aacaaagcgg
    46441 attagtacac tttctgatga ccagaatatg ctttttaatc cgctttcttt aaataacgta
    46501 ctgtaatttt tacagaaatt tttacagaaa ttctttcaga taagtgtatt taacatctat
    46561 cttgcattat aaatttctag aaccttctct tttatattcg attcactcaa accatactca
    46621 ttaagaagat aatccatttt ccctacttga ccgaatcttt cttgaacacc catccgatga
    46681 atttttgtta ttccatcatc agagaataat tcacataaag cactgccaat tccacctatc
    46741 tgattgtggt tttctacagt aaatatagtt tttccactta acattgtttt tatctgttct
    46801 ggtatcggtt tgattctaaa taaatctatc acacttactg aataacctaa tttagacagt
    46861 tcatctgcaa ctcgaatact tggagcaacc attatgccag aagcaacgat tacaagatct
    46921 tcaccatgcc ttaactcaat gtagccttta gaaaaatctt ctccaccttg atacacagga
    46981 actggagctt ttctaattgt tcgaatatat tttagtcctt ttaagtctaa tgtctggttc
    47041 aatatttcac gaaattggat atcatcagtt gcttcaaaaa tgatcgattt aggaattaaa
    47101 cgtaacaatc caatttcttc aaatggcata tgtgtcccac cattcatttc tgcagttact
    47161 cctgcatctg atccaatcac agtggcatcc aattgtgcgt atccaagaga aataaataat
    47221 tgatcaaata ctcttcgtga agcaaaagga ccaaatgtat gaagataagg tctaaacccc
    47281 tgaatagaca agcctgctgc aaggccgacc atttctgctt ccataatccc aacattcaca
    47341 taacggtctc caaagtcctt ttcaagatta tgagtagcca tcgaacttga caaatcggct
    47401 tctaagacta ctatatcaga atcactttga ttagcctcta aaaggaagtc tctatataca
    47461 tgccgtaatt ctttcgtgct tctcatcatt ctgtttcctc caattcctga cttaatcttt
    47521 ctacaactga ggttaacatt tgtctctcct ctacagtagg gcgaagatga tgattggatt
    47581 tcatttcttc cagctcttga accccttgac ctttaatagt atctaataca atgcacttag
    47641 gtgatgaatt atttgactgt tttaattgga caatcccttc ataaatttct ctaatatctg
    47701 aacccttgac cctaatggat tcaaatccaa atgctgaaaa tttttctacg aaatcacctg
    47761 gattacaaat atcctttgta aaaccatcta attgtttttt gttatcatca acaaatacaa
    47821 ttaagttgga taactgttga tgagaagcaa actgtatagc ctcccaacat tgtccctcat
    47881 ttaactcacc atctccaaca atagcataag tataaaaggg actctttctt attctctgac
    47941 catatgcaag tccagttgca acactaattc cttgtcctaa agagcccgtt gtcatatcta
    48001 tgcctggcgt tagatttcta tcaggatgag acggtaattt ggttccattt gtatttaaag
    48061 aatataagaa ttctttgtca aagaaaccat tcaaatagag tgtactgtat agagctggtc
    48121 ctccatgacc ttttgataat atgaaataat ctctatctcg tgctgcaaat atttctggag
    48181 tcattggcat tatttcacca taaagcactg ctaaaacttc tacgatagac agacttcctc
    48241 cgtaatgtcc gaatccaaga tgattcaatg ttctaagagt atttaatcgg atgttagtcg
    48301 caaattttct taactcatct tctctatttt tacttaaaat catcccttat tcctcctttg
    48361 cagatggctt tttaataaag gatactccaa acataactgc tagaataaga acaagaccaa
    48421 tcacaatgcc tgcttgtgag ccaaattgat ttaacattcc taaaataatt cctgatagac
    48481 caaaatctgc atctgagaaa gttgatcctt ggaaaccaag tcctcccaaa actggcatta
    48541 aaaagactgg aagaaaactg attaaaatac cttgtaaaaa tgctccaata gtggctccac
    48601 gaacaccacc agatgcattc ccaatgacac ctgcagtcgc tccacagaag aaatgaggca
    48661 caacacctgg taagataaca accgttcctg aagcaatcat aattgccata cttactaaac
    48721 caccaacaaa actagagata aatccaatta gaactgcatt gggtgcataa gtataaacaa
    48781 tcggacaatc caaagcaggt tttgaattag gtacaagacg ctctgaaata cctttaaagg
    48841 ctggaacaat ttcgcccaaa ataaggcgaa cacctgctaa aataacaaat acccctgctg
    48901 caaattgacc tgctaattgt aaagcataaa ctagaccact tgtaccacta ctgatttctt
    48961 tttctatata ttctgaccct gcaaagatag ctacaataat gtaaataact gccatggata
    49021 aagtaatact aacagtacta tcacgtaaaa aagctaaact ctttggaaat ttaatgtcct
    49081 ctgttgattt tgatttgtca ccgataaggc taccagtaaa accactcaac caatatccca
    49141 aagaactgaa atgacctaaa gccaccttgt catttccagt taattgaacc atatattttt
    49201 gaacaaatgc tggggaaata ctcataataa taccgagtgc taatcctcct agtaagataa
    49261 gaggcaagct agtaaagcca gcaactgata aaatgaccgc aatcatacat gccatatata
    49321 gagtgtggtg ccctgttaaa aaaatatatt taaatcgagt aaaacgagcg attaagatat
    49381 tgaacaccat gcctgcaaac ataatcagtg cagtagctga gccatatgtt gttaaagcta
    49441 cagctacaat tgcttcatta ttcggcacaa cgccagataa atgaaaagca tgctcaaaca
    49501 tggtaccaaa tggatttaaa gaattttgta caattcctgc accaccagat acaactaaga
    49561 aaccaacaaa ggtcttaatt ccacctttaa taatatcagg taatttcttc ttctgaagaa
    49621 ctaatcctaa aattgcaatt aaagctacta aaatagctgg tgtactaaca atatccaata
    49681 tgaacttcat catgacgcta gcctcctata taagtccttt ttcttcacaa agtttagtaa
    49741 ttaattctcg tagttcatcc atatcaataa tactatttaa gatacgaaca tctccaagat
    49801 gactagctga atcagctaga tcacgaccaa caatccaaat atcagctgca tttggatctg
    49861 ctccacctaa atcataatgt tcaacttcta catctgaaac attcaaatca ctcaatacag
    49921 attcaatatt catctgtacc ataaaacttg aacctaatcc tgaaccacaa gctgtaccaa
    49981 tttttaacat tatctaatcc tcctgtttaa ttatcatttt aatgtcatca tagttttttg
    50041 atgatattaa agtttgaaca tgatttttat ctcttaaaat tgttgttaaa tgtgacaaag
    50101 cctttaaatg actctcatta tcaatggctg caatacaaat caacaatctt acctcttgtt
    50161 ctggattatc caataaataa atcggttctt ccaaaactaa cattgacatt cctatttcat
    50221 tcacaccttc atctggccga gcgtgaggaa ttgctactcc cttccctaaa ttaataaaag
    50281 gcccaaactc ttctactttt tgaatcattg cctcagggta gttctcagtt atcttatctt
    50341 gatccaaaag cggtttagct gctaaacgaa tcgcctcctt ccatcctaat ttttgcgaac
    50401 taacctgata ggtttctttg gtaatgagtt gttctagcac tggtacaatt tcctttctat
    50461 catttttttg gtaaagataa ttctttaacg ccaatcttaa ttccaattct tgtgtaataa
    50521 ttccatatct tttgacaata ttcagaattt gttcaatctc aaaatcccca tactctaaat
    50581 tcggaaaatc ttttaacact agttctacta gttgtattgc ttgctcttca gtcatcataa
    50641 ccgaaactag ataatttggc ttttctgtct ccacctttat ggtagaaaaa accatatcat
    50701 agtcactact agctttcacc tgtaaatcat caatctttga ggttcctata aactcaattt
    50761 gaggaaataa tgctaataga ttctctttta acatcaatga agaactaaca ccattaggac
    50821 aaatgattgc tgctttatac catttttgag gcaaagtatc tgctttcttt aaataacctc
    50881 cgaaatggat aacaaaatat gctgtttcac tatcaggtat gggattgtca atagcgtcca
    50941 tcaagggcat caaagaatct ttgactaatt caaataaatc aggataatat tctttaacat
    51001 gcaatacata ttcatttgaa ctaggtaggc cgaactttaa tctatagtaa gccggtataa
    51061 ggtggcggcg aagattttct ctcaatcctt ccctttgttt aaaatgtaac aaagaaatat
    51121 cttccattct acttataata gcctctgtta attgattaaa gtaaaccgga gcaacatcta
    51181 cttcaccttc aaagcaactt gataataaaa cggtgatata gcgataatca tcctcagaaa
    51241 acaccgtatc tataattccc aaatcaacca ctgtatccaa taaaatagtg gttatatctt
    51301 gaataacagg agatactaat gtctctgaaa gacatactct ttcaacatcc ctttgatacc
    51361 tacacagaat gaatactaaa ccgaaaaggt aaacttttaa ttgattaaca ataggtacta
    51421 gctgtagctt ctcataataa tctttaacta cctgatttat caaatcataa gttaatgaat
    51481 acccccaact ggataaaaca taatccaaac cccaaatccc tatggaggat tccagcaact
    51541 cactaaccat ttgaaaagct aagcggtgct tattccactc tgaaccgtgt aaagtataac
    51601 cttttgctct actgtaccct agctccaaat cattatctaa cataatcttt cttaatgatt
    51661 gaatatcaga taaggttgta ttcttactta ctttcaaaaa gtcttggtaa tgattattcg
    51721 atataaaatc taatcggcaa aaagtgtaaa gatagattaa agctaagcga gtcgactttg
    51781 gtaaaaccaa ttcatccgac ttaataatat ctgtcaaaga ctgcttcgta cgatttgata
    51841 aactatagcg accttgtttt ttatccagca ctatcccttt attagctaga taaggcacta
    51901 aataatctat tccttctttg acttccttta taggtaagct caccttaaca gataattcat
    51961 ataatgatag ctcacaatga tccatcaaag tcatcaaaat aactagtgct ctataatcaa
    52021 acatttctct tcctttctaa ctacaattat agtgtaaaaa ttataagaat aaaagagtat
    52081 ttgagcacaa tataatctca ccttttaaaa gaaattattg ggctgaaagt ttttagtgat
    52141 tattttcaac tttctattga cttttaaaaa caaagtgata tcatttagat atcaaataat
    52201 gggaggtcat tcttatgact gaaaaactaa tcaattcaaa accaaatggt gtattcgcat
    52261 tgattctcat tgagttgaca atcatacttg gtatctttat atttataatg ggtgttggtt
    52321 cggaaaacat ttttggaatt attatcggac ctttactaat cgtaattgca ggtctagctc
    52381 atgctggttt aaaagttgtc aaacctcagg aagctctggt tctgacactc tttggtaatt
    52441 atacaggtac catcaaagaa cctggttttt actttgtcaa tcccttcagc gtagcagtca
    52501 accctgcaaa ccacactcga cttggacaaa gtggtgatgt tagcacaaaa tctccttttt
    52561 taggagctaa atcatcaaat gacaatgatg taaatcttga aattggcaag aaacacattt
    52621 ccctcaaagt catgaccttg agcaattctc gtcaaaaaat caatgattgc ttaggaaacc
    52681 ctgtagaaat cggtatcgcg gtaacttgga gagttgtcga taccgctaag gcagtcttca
    52741 acgttgataa ctacaaagaa tatctttcat tgcaatgtga tagcgccctc cgtaatattg
    52801 tccgcatcta tccttacgat gtgtctccta atgtggatac tacgggtgac gggcaagcag
    52861 atgaaggtag tctccgtggc tctagcgaaa ttgttgctaa ccgtattcgt gaagaaatcc
    52921 aaagtcgtgt tgaggatgct ggcttggaaa tccttgaagc acgtatcact tacctagctt
    52981 atgctccaga aattgctgcc gttatgcttc aacgccaaca agcatctgcc attattgatg
    53041 cacggaagat gattgtagat ggtgctgtag gaatggttga aatggcacta gaacggctca
    53101 atgaagggga attggtagaa cttgacgaag aacgaaaagc tgccatggtt tcaaatctcc
    53161 ttgtcgttct ttgtggcaat catgatgcac aaccaattgt caacacagga agtctttact
    53221 aaagatggct gaagctaaaa aaaagcagat cccccttcga ctctcaacaa agttatacgc
    53281 tgcactcgca tcatgggcag aagacgactt tcgttcagtc aatgggcaaa tcgaatatct
    53341 cctcacagag tgtgtcaagc aacggaagaa agacggaaaa tacgtatcag aaaccattga
    53401 cgaaccattt gagattgata tttaacatct tctcctgtct gacaagtcgg acaggagaat
    53461 tttttcatct ttttttgtca agtaacttta ctttacaaaa aaaatgtgtt atcctagtat
    53521 ggttgatgaa aatcagtaga ttgaatcgaa tataaatacc taaaggagaa atcaaaatgg
    53581 cagtacctgc acgtcgcact tcaaaagcga agaaaaacaa acgtcgtaca cactacaaag
    53641 taacagctcc atctgtaaac tttgacgaaa ctactggaga ttactcacgt tctcaccgtg
    53701 tatcacttaa aggatactac aaaggacgta aaatcgctaa agctgcatca gctgaataat
    53761 agaagggaga taccatgcgc gtaaatatta cacttgaaca caaagaatct ggtgaacgct
    53821 tgtaccttac ttctaaaaac aaacgtaaca ctccagaccg ccttcaattg aagaaatact
    53881 caccaaaact tcgcaaacac gttgtgttta cagaagtgaa gtaagcattc aatacgaatc
    53941 aatacagaag aaaaacgctt gatcagcgtt ttttcttttt gttaatttca ctatattgca
    54001 agggaaatca ttcgaatgac tacctttttc actacctttt ttgaaataag aatacggatt
    54061 cggacgatta aaagtaagag aaactcaaat gtaagttggg gttccttttt tgtatatttt
    54121 tcaaataacg cctctacact atttgtagca aattcaccaa ctacagttgt atcttagtta
    54181 aaataagtta gaatatgtaa gtgagtacca gatataccaa gacatcgtca ccatctaagg
    54241 tatattcaaa atacaaaagt tgaccaacta gatttctgaa tatccttata tatccattct
    54301 taaaattggt ttaaatagcg tagtctttta aactagtttt gagaatccaa aaaatcttcc
    54361 tacatatgta agaagatttt ttagttcaga atgattagat ttagctaatg gatacctatc
    54421 ctacccactc accgttagca ttgactcgat agccatcggg tgtagtcgtg tttactaata
    54481 aatctcctga attataggta tagtaccatt taccagaaac tgtaa
//
LOCUS       DAVHBD010000009        52879 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000009 DAVHBD010000000
VERSION     DAVHBD010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52879
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.009"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(56..1018)
                     /locus_tag="VVK04_000544"
     CDS             complement(56..1018)
                     /locus_tag="VVK04_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU3989243.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            1084..2472
                     /locus_tag="VVK04_000545"
     CDS             1084..2472
                     /locus_tag="VVK04_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU3989244.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            complement(2507..2959)
                     /locus_tag="VVK04_000546"
     CDS             complement(2507..2959)
                     /locus_tag="VVK04_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU3989245.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            3121..3414
                     /locus_tag="VVK04_000547"
     CDS             3121..3414
                     /locus_tag="VVK04_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989246.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            3570..4784
                     /locus_tag="VVK04_000548"
     CDS             3570..4784
                     /locus_tag="VVK04_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU3989247.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGGGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            4929..5063
                     /gene="rpmH"
                     /locus_tag="VVK04_000549"
     CDS             4929..5063
                     /gene="rpmH"
                     /locus_tag="VVK04_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU3989248.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAV
                     "
     gene            5326..5979
                     /locus_tag="VVK04_000550"
     CDS             5326..5979
                     /locus_tag="VVK04_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU3989249.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKLETTPGGDKGGNTGSSD
                     ANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKNKQDEIKGAPL
                     SDKEKAELLARVEAKKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRLVAPKTT
                     SAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTRHRK"
     gene            6284..7057
                     /locus_tag="VVK04_000551"
     CDS             6284..7057
                     /locus_tag="VVK04_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU3989250.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            7057..7617
                     /gene="rnmV"
                     /locus_tag="VVK04_000552"
     CDS             7057..7617
                     /gene="rnmV"
                     /locus_tag="VVK04_000552"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU3989251.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            7689..8588
                     /locus_tag="VVK04_000553"
     CDS             7689..8588
                     /locus_tag="VVK04_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3989252.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            8857..10887
                     /locus_tag="VVK04_000554"
     CDS             8857..10887
                     /locus_tag="VVK04_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU3989253.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSIYYQGLFTDYL
                     QNFSSESVEVTSQKYYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRDLMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            10889..11530
                     /locus_tag="VVK04_000555"
     CDS             10889..11530
                     /locus_tag="VVK04_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989254.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNSLVWNKADEIIDMRKLAHV"
     gene            11523..11681
                     /locus_tag="VVK04_000556"
     CDS             11523..11681
                     /locus_tag="VVK04_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989255.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQILVHGYL
                     LDFASIEG"
     gene            12067..12939
                     /gene="rsmA"
                     /locus_tag="VVK04_000557"
     CDS             12067..12939
                     /gene="rsmA"
                     /locus_tag="VVK04_000557"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU3989256.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            12941..13819
                     /gene="rsgA"
                     /locus_tag="VVK04_000558"
     CDS             12941..13819
                     /gene="rsgA"
                     /locus_tag="VVK04_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU3989257.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            13830..14486
                     /locus_tag="VVK04_000559"
     CDS             13830..14486
                     /locus_tag="VVK04_000559"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU3989258.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            14449..15111
                     /locus_tag="VVK04_000560"
     CDS             14449..15111
                     /locus_tag="VVK04_000560"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU3989259.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            15113..16369
                     /locus_tag="VVK04_000561"
     CDS             15113..16369
                     /locus_tag="VVK04_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU3989260.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            16359..17300
                     /locus_tag="VVK04_000562"
     CDS             16359..17300
                     /locus_tag="VVK04_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU3989261.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            17567..18394
                     /gene="purR"
                     /locus_tag="VVK04_000563"
     CDS             17567..18394
                     /gene="purR"
                     /locus_tag="VVK04_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU3989262.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            18461..19711
                     /locus_tag="VVK04_000564"
     CDS             18461..19711
                     /locus_tag="VVK04_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU3989263.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            19837..20631
                     /gene="pflA"
                     /locus_tag="VVK04_000565"
     CDS             19837..20631
                     /gene="pflA"
                     /locus_tag="VVK04_000565"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU3989264.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(20706..21632)
                     /gene="yidC"
                     /locus_tag="VVK04_000566"
     CDS             complement(20706..21632)
                     /gene="yidC"
                     /locus_tag="VVK04_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU3989265.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(21710..21988)
                     /locus_tag="VVK04_000567"
     CDS             complement(21710..21988)
                     /locus_tag="VVK04_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU3989266.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22022..22762
                     /locus_tag="VVK04_000568"
     CDS             22022..22762
                     /locus_tag="VVK04_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU3989267.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVYISMKGQAESLNVAVAAGILIFYLS"
     gene            22818..23501
                     /locus_tag="VVK04_000569"
     CDS             22818..23501
                     /locus_tag="VVK04_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU3989268.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            23613..24605
                     /locus_tag="VVK04_000570"
     CDS             23613..24605
                     /locus_tag="VVK04_000570"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU3989269.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            24670..25209
                     /gene="rsmD"
                     /locus_tag="VVK04_000571"
     CDS             24670..25209
                     /gene="rsmD"
                     /locus_tag="VVK04_000571"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU3989270.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            25199..25687
                     /gene="coaD"
                     /locus_tag="VVK04_000572"
     CDS             25199..25687
                     /gene="coaD"
                     /locus_tag="VVK04_000572"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU3989271.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            25671..26708
                     /locus_tag="VVK04_000573"
     CDS             25671..26708
                     /locus_tag="VVK04_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU3989272.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            26766..26996
                     /locus_tag="VVK04_000574"
     CDS             26766..26996
                     /locus_tag="VVK04_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU3989273.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            27020..28303
                     /gene="murA"
                     /locus_tag="VVK04_000575"
     CDS             27020..28303
                     /gene="murA"
                     /locus_tag="VVK04_000575"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU3989274.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            28296..28484
                     /locus_tag="VVK04_000576"
     CDS             28296..28484
                     /locus_tag="VVK04_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU3989275.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            28523..29347
                     /gene="endA"
                     /locus_tag="VVK04_000577"
     CDS             28523..29347
                     /gene="endA"
                     /locus_tag="VVK04_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU3989276.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            29638..30969
                     /locus_tag="VVK04_000578"
     CDS             29638..30969
                     /locus_tag="VVK04_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU3989277.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(31167..31237)
                     /locus_tag="VVK04_000579"
     tRNA            complement(31167..31237)
                     /locus_tag="VVK04_000579"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31203..31205),aa:Cys,seq:gca)
     gene            31653..35264
                     /gene="rpoB"
                     /locus_tag="VVK04_000580"
     CDS             31653..35264
                     /gene="rpoB"
                     /locus_tag="VVK04_000580"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU3989278.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            35297..38974
                     /gene="rpoC"
                     /locus_tag="VVK04_000581"
     CDS             35297..38974
                     /gene="rpoC"
                     /locus_tag="VVK04_000581"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU3989279.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            39085..39498
                     /gene="ndk"
                     /locus_tag="VVK04_000582"
     CDS             39085..39498
                     /gene="ndk"
                     /locus_tag="VVK04_000582"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU3989280.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(40428..41060)
                     /locus_tag="VVK04_000583"
     CDS             complement(40428..41060)
                     /locus_tag="VVK04_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989281.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(41062..43077)
                     /locus_tag="VVK04_000584"
     CDS             complement(41062..43077)
                     /locus_tag="VVK04_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU3989282.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFGALTLISQISQLRSSGIRLISGEKRWSIFLRPVGDDLKGIAVGFSLAGVLTI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            complement(43222..43392)
                     /locus_tag="VVK04_000585"
     CDS             complement(43222..43392)
                     /locus_tag="VVK04_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989283.1"
                     /translation="MKKNRGIQKLAILVLLGIFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            43581..44444
                     /locus_tag="VVK04_000586"
     CDS             43581..44444
                     /locus_tag="VVK04_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3989284.1"
                     /translation="MNTFAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIAFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDAV"
     gene            44827..45447
                     /locus_tag="VVK04_000587"
     CDS             44827..45447
                     /locus_tag="VVK04_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989285.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            45533..45976
                     /gene="tsaE"
                     /locus_tag="VVK04_000588"
     CDS             45533..45976
                     /gene="tsaE"
                     /locus_tag="VVK04_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU3989286.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            45966..46484
                     /locus_tag="VVK04_000589"
     CDS             45966..46484
                     /locus_tag="VVK04_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989287.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            46492..47508
                     /locus_tag="VVK04_000590"
     CDS             46492..47508
                     /locus_tag="VVK04_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU3989288.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            47593..48849
                     /locus_tag="VVK04_000591"
     CDS             47593..48849
                     /locus_tag="VVK04_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU3989289.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNRLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            48904..50070
                     /gene="recA"
                     /locus_tag="VVK04_000592"
     CDS             48904..50070
                     /gene="recA"
                     /locus_tag="VVK04_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU3989290.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            50377..51747
                     /locus_tag="VVK04_000593"
     CDS             50377..51747
                     /locus_tag="VVK04_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU3989291.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            52123..>52879
                     /gene="lytA"
                     /locus_tag="VVK04_000594"
     CDS             52123..>52879
                     /gene="lytA"
                     /locus_tag="VVK04_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU3989292.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFN"
BASE COUNT        15583 a        10016 c        12039 g        15241 t
ORIGIN      
        1 aaccatacat acggtaaggc gacgtgacgt ggtttgcaga gattttcgaa gagtattagc
       61 cttccatata gtctttcaaa gcctgtcctg ttagtccggc attgagggcg atgaggagtt
      121 tcaagcgagc tttttgggcg ttgagttctt taacaaagaa aacgcctgct ttttgcaact
      181 gtacgccccc accctggtag gcataaacag gctcggcaat accgttaaag catcgtgata
      241 ccagagcgac tggaattcct ttttgcagaa ggctttctaa tttttgagcc gtttctttgg
      301 gaatattacc agctccgaag gcttggataa tcaaaccgtc caagtgttct aaatccagca
      361 tatcaatcag ctcatctgtc ataccagcat aagccgagat gatagggact aaaccttgta
      421 tgtgatcaag gtcaaagcga acacgaggtt cagctgtttt gaagtagagg atttcctgtt
      481 tcatgatgag accaaggggg ccatgtgttg gagtctggaa ggtgctgaca ttagtcgtat
      541 gtgttttggt gacatacttg gcagcgtgga tttcatcgtt cataacgacc aaaactcctt
      601 tgtcagcagc cctgtcatcg ctggccactc gtaaagcact taggtaatta taaacaccat
      661 cactaccgag ttcattggag ctacgcatgg ctcctgttag aacgataggc atatggggaa
      721 cttccatggt atcaaggaaa taggctgttt cctctaaagt atcggttccg tgtgtgatca
      781 ccactccatc gtagttatct gcttcctctt taattttctg gtagaggacc agcatatgtt
      841 tgggtttgat atggggactt ggaaggttaa aaaagtccaa ggcgtggact tggattcctt
      901 caagtgggtt ggacacatgg ttcatgggat tatctgaact cgtcacaaca gcgccagaag
      961 catcggcctg catggaaata gttccacccg tatgtaaaac aaggattttc ttaggcatga
     1021 tttactcact ctttctgaaa tgtggtataa tcattgtatc acaaaagggg agattgggat
     1081 aggatggaag tcaaagctgt tttttttgat atcgatggaa ccttggtcaa caatcgcaag
     1141 agtgttttga aatccactaa ggatgcgatt aagattgtca aagaacaagg ggtactagtt
     1201 ggcgtagcga cagggcgagg accttttttt gttaaggaat tgatggacga tttggatctg
     1261 gattttgcgg taacctataa tggccagtat atctttagta aagacagagt cttgttcacg
     1321 agccctattt ccaagttaca tttgcgccat ctaattagct atgctaaaaa agagggcacg
     1381 gagattgcct tagggaccaa ggatgccatg ttgggttcta aaatcatgtc ctttggtctg
     1441 ggttcttttt cccaacgaat tagtcgcttc gttccctctg ttttaactcg gacggtgagt
     1501 cagtctttta atcgcatggt cagcaaggtt gttccccaaa aggaagagga cctgcttcac
     1561 ctgatgaatc aacctattta ccaagttttg atgctgatga caccagaaga atctgagaag
     1621 gcggcagctg attttgaaga cttgaaattg acacgtagca atccttttgc atcggatgtc
     1681 atcaatcagg gaaattctaa attagaaggc attcgccgag ttgggaaaga atatggcttt
     1741 gacctcaacc aagtcatggc ttttggtgac tcagataatg accttgaaat gctggctggc
     1801 gtcggtatgt cggtcgctat gggaaatggt agtagcagtg tcaaggaagc tgccaagcac
     1861 attaccacta gcaatcaaca agatgggatc cacaaggcct tggaacattt tggtgttttg
     1921 tcttcagaaa aagtttttgt cagccgtgac tatcatttca ataaggtcaa gaccttccac
     1981 cacatgatgg atgaacgaac ccaagaagaa cctcgagctt gggatttaga gggtgcaacc
     2041 catagggctg gttttaaaat agaagaattg gtggagtttg ttcgagcagc cagtccttct
     2101 gaagaagatt ttggtcaagc tgtatcgcaa cttcatcagg cccttgataa ggcagcagat
     2161 aaagtagcca agaagacacc tgctcagcaa gatttgatag ggcaagtgga tgccttgatt
     2221 gacacgcttt acttcaccta cggcagtttt gtcttgatgg gggtggaccc agaacgtatt
     2281 tttgatattg tccatcaggc caatatgggg aaaatttttc cagatggcaa ggctcatttt
     2341 gatccagtga cccataaaat cttaaaacca gataattggg aagaaaaata tgctccagaa
     2401 cctgctatta aaaaggaact gcagcgccag ctcaaggctt acgaacgcca taaagagaga
     2461 aataaatcgt aaacaaaaag gagctagggg ctccttttct ttgtgattat aaggtttttt
     2521 cttgttctct cacaaccagc aaatcgacct tagcatggcg gagtatgtat tcagatgaag
     2581 agccgaccaa gaggcgttca aaggcgttga gaccagttgc gccaacgagg atgaggtcca
     2641 cttcctcggc atctggaata gtacgtgcta gcagggtctt tggatttccc atttcaatga
     2701 cgatatgaac atctgctacc ccagcatctt tagcacgttt ttcgtactct ttcatcagac
     2761 tttcagcgtc gacttggagt tcttcgtaaa cttcagcatc aaaggtggat acgctttgga
     2821 gagcgcgtgt gtcaatgaca tgtgcgatgg tgagtttagc gtcgtttcgt agagcagaat
     2881 gaactccctt gacaaaagcc aagtccgctt ccttagaacc atcgattgcg accatgatat
     2941 tttggtaacg ttgtgccata atgaaacctc ctgaaatttt cttactataa ttgtaaacct
     3001 tttcactata gaagtaaagc aaaaaaagta tttttcaaaa gaatattagg gcttaaaatc
     3061 tatataaata tatgataaaa taaaagaaag gatagcagga aagaagtgaa ggaagggaga
     3121 atgatgaaaa actcttttca aaaatcaaat ttcctgtatt atggaattat cctagtttca
     3181 gtcttggtag aagtgatcat gatctggcaa ttagagagtt tggtaccgct tatttatcca
     3241 ggttttattg gatttttagt ctttcatgta ctctaccatc taatcttatt tctagttgca
     3301 aaacgaagtg ggcgttggga ttacttgatg atatgggggc ttttcctcat gtttaatctt
     3361 ctttatgact cctttctagg cttgcttttt ctaggtttat cttttggtat gtgatgtgtc
     3421 tttgcaaaat acctgctatc tctacgttct taacctcgcc tttagcaagg tttttcttct
     3481 atacgaaact agtaacacat ttcagtaaac ttgtcgcatt ctctttctag tggtataatg
     3541 ttactatcct gatgaattga ggaaacaaga tgaaagaata taacaagtct agtaagttag
     3601 agcatgttgc ttatgatatc cgtggtcctg tattggaaga agccatgcgg atgcgagcga
     3661 atggagaaaa gattttacgt ctgaatacag gaaatccagc agaatttggc tttacagcgc
     3721 cagacgaggt cattcatgac ttgattatga atgcgcgtga tagtgaaggc tattctgact
     3781 ccaaagggat tttctcagcc cgtaaggcca tcatgcagta ttgccagctg aagaaattcc
     3841 caaacgtaga tattgatgat atttaccttg gaaatggtgt cagtgagttg attgtcatgt
     3901 ccatgcaggg gcttttggac aatggggatg aggtcttagt gccaatgcca gactatcctc
     3961 tatggacggc ggctgtcagc ctagctggag gaaatgccgt tcactatatc tgtgatgaag
     4021 ctgtggaatg gtacccagat attgacgata tcaagtcaaa aatcacttcc aataccaagg
     4081 caattgtcct tatcaatcca aataacccaa ctggagccct ttatcctaag gaactcttgc
     4141 tggggattat tgagattgcc cgtcaaaacg atttgattat ctttgcggat gaaatctatg
     4201 accgcatggt aatggacgga catgtgcata cgcctgtggc gagcttggca ccagatgtct
     4261 tctgtgtcag catgaatggt ctgtcaaaat cccaccgcat agcaggtttc cgtgtgggtt
     4321 ggatggtctt gtctggccct aagactcatg ttaagggcta tatcgaaggg ctcaatatgc
     4381 tgtccaatat gcgcctttgc tctaacgttt tggcccaaca agtcgtacaa acttccttgg
     4441 ggggtcacca atcagtcgat gaattgcttc ttcctggtgg acgaatctac gagcaaagaa
     4501 atttcatcta taatgccatt caagatattc caggtttgtc tgccgttaaa cccaaggcgg
     4561 ggctctatat cttcccaaaa atcgaccgca atatgtaccg tatcgatgat gatgagcagt
     4621 ttgtccttga tttcttgaag caggaaaagg ttctcttggt tcatggtgga ggctttaact
     4681 ggcaggaacc agaccacttc cgtatcgttt accttcctcg tgttgatgag ttagcccaaa
     4741 tccaagaaaa gatgactcgt ttcttgaaac agtatcgtag atagggcttg cattcgaaaa
     4801 agctggaaac atttgcctag agctattgac aaaagtgaaa gaatcagata gaatagtaaa
     4861 gtatgtttag taactgatca ctttatagcc ggctaaacga atacaaaatc tatgaggagg
     4921 tattcatcgt gaaacgtact tatcaaccaa gtaaacttcg tcgtgcgcgc aaacacggat
     4981 tccgtaaccg tatgtcaact aaaaatggtc gtcgcgtatt ggcagctcgt cgtcgtaaag
     5041 gacgcaaagt tttggctgta taatccaaac gaattctatc aaaaatcagt aggaactcga
     5101 gtctactgat ttttattttt gtaaaaaagt tcagtagatg caaatggatt tggaagcgat
     5161 gttatagtag attgaaacta gaatagtaca cctctatttc taaaacattg ttagaaatcg
     5221 atttgactgt cctgatcgat ttgtcctgtt attattttat tttactataa agttgaagta
     5281 gctggagatg gtacagcaac aatcacattc ccagatggtt cagtagtgac gattctagga
     5341 aaagatacag ttcaacaatc tgcgaaaggt gaatctgtaa ctcaagaagc tacaccagag
     5401 tataagctag aaactacacc aggtggagat aagggaggca atactggaag ctcagatgct
     5461 aatgcgaatg aaggcggtgg tagccaggcg ggtggatcag ctcacacagg ttcacaaaac
     5521 tcagctcaat cacaagcttc taagcaatta gctactgaaa aagaatcagc taaaaatgcc
     5581 attgaaaaag cagccaagaa caagcaggat gaaatcaaag gcgcaccgct ttctgataaa
     5641 gaaaaagcag aacttttagc aagagtggaa gcaaaaaaac aagcagctct caaagagatt
     5701 gaaaatgcga aaactatgga agatgtgaag gaagcagaaa cgattggagt gcaagccatt
     5761 gccatggtta cagttcctaa gagactagtg gctcctaaga caacaagtgc accgcaagca
     5821 actgcaggaa caatgcaaga tgttacctac cagtcacctg ctggcaaaca attacctaac
     5881 acaggttcag catcaagtgc agcacttgct agtcttggtc tagtggtggc aacaagtggt
     5941 tttgctttgc taggaagaaa gactagacat agaaaataga acagctagaa aattctattc
     6001 tctacttaaa gttagattat aagggggatt ttgagaagtc atcaatccta gtgatgggtg
     6061 agaaaagtga gaacccaaga taatcacata ctttagctga ataggaatat tctatcaatg
     6121 tagccaatct cttctgtctc taactgtgga ataggagatg ggcaatatcg gatagaaaag
     6181 atagcagaat agctctctat tgaagagagg aggggaaacc gaaaaattag gtgcccctcc
     6241 tcttttttgg tataatagaa gatagaaaac gaggttagaa gagatgattt ttgatacaca
     6301 tacacacttg aatgtagaag aatttgcagg tcgtgaggca gaagaaattg ccttggctgc
     6361 tgagatgggt gtgatacaga tgaatattgt tggttttgat aaaccgacga ttgagcgtgc
     6421 cttggagttg gtagatgagt atgagcagct ctatgcgact attggttggc atcctacaga
     6481 agctggtact tatacagagg aagttgaggc ttacttgttg gataagttaa aacattccaa
     6541 ggttgtggct ttaggtgaaa ttggcttaga ctaccattgg atgacagcgc ccaaagaggt
     6601 gcaggagcag gtttttcgcc gtcagattca gctatctaag gacttggatt tgccttttgt
     6661 tgtccatacc cgtgatgcgc tggaagatac ctatgagatt atcaagagtg agggcgttgg
     6721 tcctcgtggt ggtatcatgc attcattttc agggacgctt gagtgggcag agaagtttgt
     6781 ggatcttggt atgaccattt ccttctcagg agtggtgact ttcaagaagg caactgacct
     6841 ccaagaagca gctaaagagt tacctttgga caagatgttg gtggaaacag atgcgcctta
     6901 cttagcacct gtacccaagc gtggtcgtga aaataaaaca gcctatactc gctatgtggt
     6961 cgactttatc gctgacttgc gtggtatgac gacagaagag ctggcggtag caacgactgc
     7021 aaatgcagaa cgaatttttg gattggacag caagtaatga aagagaaaat ttctcaagtt
     7081 atcgtggttg aaggtcgcta tgatacggtc aatctcaagc gttatttcga tgtggagacc
     7141 tatgagacac gaggttctgc catcaatgat caggatatag agcgaattca gcgtctacac
     7201 caacgtcatg gagtcattgt ctttacagac ccagatttta atggggagcg gattcggcgc
     7261 atgattatga cggccattcc aacagttcag catgcctttc tcaagcgaga tgaagctgtt
     7321 cccaagtcca agaccaaggg gcgttctctg ggaattgagc atgccagcta tgaagacctg
     7381 aaaacggctc tagctcaggt gacagaacaa tttgaacatg agagtcagtt tgacattagt
     7441 cgtagcgact tgattcgcct tggttttcta gcaggggcag acagccgtaa gcgtagagaa
     7501 tatctcggag agactctccg aatcggctat tctaacggca agcaactcct caaacgccta
     7561 gagttgtttg gggttacttt ggcagaagtg gaagaagcta tgaaatctta tgagtaggaa
     7621 agatgtagcc gttacaattt tttaagtttc acagtatttt tcgaagcagg tagaagagga
     7681 ggcgtctgat gttaattggt caaaaaatta aagagattcg gatagaaaaa ggaattagtc
     7741 gtccagattt ttgtggagat gagcaagaac tgacagttcg tcaactgtcg cgaattgaaa
     7801 gtggagcttc gcaaccgagt ttgcccaagt tagcctatat tgctcgccgg ctaggagttc
     7861 cagtttatag ccttatgccg gatttttcag ctcttccttc tgcttattta gaattgaaat
     7921 accagatttt acgtgaacca atctatggta aagaagagga gtacgataag aaggaagcgt
     7981 gtttggaaga gatttataaa acatactttg ataatcttcc taaagaagaa caattagcat
     8041 gtgaagtatt gcaggcgtgt ttggatactt ctagaactag aaggcctgaa tatgcagagt
     8101 taatacttga ggaacatatg cctcagatca tagaaaaaga agtttattca acaaatgata
     8161 tgttgttgat tcgtttgttt ttttatcaaa tgctcattag aaaagatctt gccaaattta
     8221 taaatcaaat cgaaaagcta atgctctttc ttttggaaca gaaaaaggta actaaattag
     8281 aaaacttctt tataattaga gatactctta tttcaggaat gtgttgtctt gaaaaggtag
     8341 gagtaactga ttgttttaat gattatctat cgtgtttaca agaaattatg gataaaactc
     8401 aagattatca aaagaaacct cttgtattta tgtttttgtg gaagcaagca ttaagagaag
     8461 aaagagattt tagtttagct gaatcatttt atcagtcttc taaaacattt gcgcagctaa
     8521 ttggagatga atttctagta aagaaattga cagaggaatg gcaagaggat gtcaaaaaat
     8581 atttataaac atagtgaatc agtgacaaaa atgtccttgt cctcgtatca aaacagttct
     8641 aaagttcgtc tttagaactg tttttttaga tataagctaa aaataatatg aaatagttag
     8701 attttaagga cattgatgtc cttgatagtt cttgaaaaaa cggatataat gtatttgaag
     8761 atgttgctag cagaaagaac ttaataagct tcttaacatc gcagtgactg tggtcacctt
     8821 ctcactaagt gaccaagtaa ctttttggag gaaatgatga aacgtttatt tattttgatt
     8881 tcaatggtat tggtatcgct ttatatggtg ataacttccg ttgaccatcg agaagagatt
     8941 ttatttggta actatccttc tgttgatgtg acaggaatga tgataaatca accagtagct
     9001 agtcgcgaag aggtgacaga ggctttgagt cacttggcgg tagagcacaa tagtctcatt
     9061 gctcgtcgaa tcgttgagcc aaatgaagct ggagaaacac gctttaccta tgccacttat
     9121 ggtgagggaa agcttccaga aggtctgacc atttcctcca aggagagtgc agaaacgagt
     9181 gatttattag ggtcttactt gattgtatcg ggaagtttgg atggagtgag cttacagacc
     9241 accttgaaag agcttggtta tcaaggcttt gtttcgaatg gagaagatcc attttcgata
     9301 gtcttactat tgacggccac ccctatggtg ctactgagtt tagctatttt tctgctgacc
     9361 tttatgagtc tgaccctgat ttatcggatc aaatcccttc gtcaggcagg gattcgctta
     9421 atagctggtg agagcttgtt tggagttgct ctcagaccag tgttagaaga tgtgagacag
     9481 cttatctgct cagtgctggt atccagtctt ttgggattgg ggattctctg gtatcaaggt
     9541 gccttgttta tggcaacggt gcaactggtc atcattgctc ttctacttta tggattgacc
     9601 ttggcaggga tttctacctt actaagtgtc gtctatctac ttggtttaca ggaaaatagt
     9661 ctggtggatc tattgaaagg gaaactccct ctcaaacgta tgatgacatt gatgatggtg
     9721 gggcaactct tagctgtatt ggtggtcgga tcgagtgcga cagctctcct accccactac
     9781 cgtgaaatgc aggaaatgga gagagctagc aataaatgga gccagtcctc agaccgttac
     9841 cgtctatcct ttggttggtc tagtgcattt gccgatgaag aaggaacgcg taaggataat
     9901 cgtgagtggc agacatttac tgaagaacgg ttagccaata cagactcttt ttatattatg
     9961 agcaatgttg acaatttctc agatggagca gaagtggacc tagatggcaa tcgtctcagt
    10021 gactacacac cgtcagggaa tgttatctat gtctcaccgc gctatctgat agaagaaaag
    10081 attaccgttt cttcagagtt tatggacaag atgcaaaact tgtctgaggg agagtttggg
    10141 ctgatcttgc ctgagagctt gcgagagcag tctatctact accaaggatt gtttacagat
    10201 tacctgcaaa acttttcatc tgaaagtgta gaagtgacga gtcagaaata ctacctccca
    10261 caggtaaggc tagcttttac agaaacagga caggaacgtt tcctctataa tgatgggtac
    10321 aagacaacac gccagtacct aaaagatccg attattgtag ttctaacgcc gcaagcgact
    10381 ggaacaagac ctgttgcagg gatgttgtgg ggaactacgg ctaatagtgc cttgaaacta
    10441 gatcgatatg gagacagcat cacagctcta aaagagcaag gtctgtatca caaggtttct
    10501 tacttggtaa aaagccagct attttttgcc aaggtactaa atgacaaacg ggtggagttt
    10561 tactctctcc ttattgggac gattttgacc ctgtctacgg ctatcttgtt atttgattcc
    10621 atgaatcttc tctattttga gcagttcaga cgggatctta tgattaaacg tcttgctggt
    10681 atgacaatct atgagcttca tggcaagtat ttactggcgc aaggaggagt tctcttgctt
    10741 ggcctagtcc tatctagtat tttgacaaga gatggtttga ttagcgctct agttgtagct
    10801 ttgtttacgc ttaacgccct cttgatttta gtaaggcagg acaaaaaaga agaagctggt
    10861 agcatggcag tattgaaagg aaaataagat gattgatatt caaggattgg aaaagaaatt
    10921 taatgaccgc gcgattttct ctggtttgaa tctcaagctg gagaagggca aggtttatgc
    10981 cttaatcgga aagagtggaa gcggaaagac gacgctgctg aatatcttgg gaaagctaga
    11041 aaagatagat ggaggaaggg ttctctatca ggggaaagat ttaaaaacca ttcccactcg
    11101 tgagtatttt cgagatcaga tgggctatct ctttcaaaat tttggcctct tagaaaacca
    11161 atcaatcaaa gaaaatttgg atttgggttt tgttggtcag aaaatctcaa aagtagaacg
    11221 tttggaaagg caagtggggg ctttagaaaa agttaatcta gggtatttgg atttagaaca
    11281 aaaaatctat actttatctg ggggagaggc ccaacgagtt gcccttgcta agactatttt
    11341 gaaaaatcca cccttgattt tggcagatga accaacagca gctcttgatc ctgaaaattc
    11401 agaggaggtt atgaatctct tggtggattt gaaagatgaa aatcgaatta tcatcattgc
    11461 gacccataat tccctagtct ggaataaggc tgatgaaatc attgatatga ggaaacttgc
    11521 tcatgtgtga aaaaatccgt attcgcaggg tatctgatta tcctagtgcc agaggtggtt
    11581 tagaagatat cctcatcatg gaaaatatga ccaatcatct ccttttggtt caaatcctag
    11641 tgcatggcta tttgcttgat tttgctagta ttgaagggta aaggcaaaag cattatcgtt
    11701 tgaaaaattt acctcaaacg gttgaactga cagtggatga tgtggaggag gatgtggatt
    11761 tgaccctacc cgaaaataga agttatcaag aagctgattt ttttgatact caatgaaaat
    11821 caaagagcaa actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga
    11881 cgtggtttga agagattttc gaagagtatg aacgtatgtt tcgagagaag cgctaagtcc
    11941 ctctttaaag atttccaaga ctatctttct tcatgaggaa agatagtttt ttggtatgat
    12001 tttcattccc aaaatacaag gggaatgtgt tacaatagta gtaacagata atagaaaaga
    12061 gaatagatga gaattgcaga ttatagcgtg accaaggcag tgctggagcg tcacggtttt
    12121 acctttaaaa agtccttcgg gcaaaatttt ctgacggata ccaatatcct tcaaaaaatt
    12181 gtggatacgg ctgaaattga tgaccaggtc aatgtcatcg aaatcgggcc aggtattggt
    12241 gccttgacgg agtttctggc tgagcgtgca gcccaagtca tggcttttga gattgaccac
    12301 cgtttggtgc caattttggc agataccctg cgtgattttg ataatgtgac tgtagttaac
    12361 gaagatattc tcaaggttga tttggcgcaa catatccaaa attttaaaaa tcctaacctg
    12421 ccaatcaagg tagtggctaa tttgccttac tacatcacga cgcctattct catgcacttg
    12481 attgagagtg gcattccttt ttgtgagttt gtggtcatga tgcagaaaga agtagcggac
    12541 cgcatttcag cccagcctaa caccaaggct tacggtagct tgtctatcgc cgtgcagtat
    12601 tacatgacag ccaaggttgc ctttatcgtg cctcgtacgg tctttgtgcc agcaccaaat
    12661 gtggattcag ccatcttgaa aatggtgcgt cgtccagagc cagccgtagc agtagaagat
    12721 gagaactttt tctttaaggt ttccaaggct agttttaccc atcgccgcaa gaccttgtgg
    12781 aataacttga caggttactt tggtaagact gaagaggtca aggacaagct gaccaaggct
    12841 ttggaccagg caggcttgtc accaagtgtg cgtggggaag ctctcagctt ggcagaattt
    12901 gccggtctag cagacgcact taaagggcaa ggactctaag atgcagggac aaatcattaa
    12961 agccttggca ggtttctact atgtggagag tgatggccag gtttatcaaa cacgcgcgcg
    13021 tgggaatttc cgtaaaaaag gccatacccc ttatgttggg gactgggtag atttctctgc
    13081 cgaggaaaat tcagaaggct atatcctcaa aattcacgaa cggaaaaaca gtctggttcg
    13141 tccgcctatt gtcaatatcg atcaagctgt agtaatcatg tccgtcaagg aacctgattt
    13201 taacagcaat ttgctggatc gtttcttggt tcttttggag cacaagggca tccatcccat
    13261 tgtctatatt tccaaaatgg atttgttgga agatagggga gaactggatt tttaccagca
    13321 gacctatggt gacatcggct atgactttgt gaccagtaaa gaggaactcc tgtctttgtt
    13381 aacaggcaag gttacggtct ttatggggca gacaggtgtt gggaagtcaa ctcttctcaa
    13441 taaaatcgca ccagacctca atcttgaaac gggagaaatt tcagacagtc taggtcgcgg
    13501 tcgccatacc actcgagctg ttagttttta caatctcaac gggggtaaaa tcgcagatac
    13561 accaggattt tcatccttgg actatgaagt atcaagggct gaagacctca atcaggcttt
    13621 cccagagatt gctactgtta gccgagattg taagttccgt acttgtaccc atacccatga
    13681 gccgtcttgt gccgtcaaac cagctgttga agagggtgtt attgcaacct tccgttttga
    13741 caattacctg caattcctta gtgaaattga aaatcgtaga gaaacctata aaaaagtcag
    13801 caaaaaaatt ccaaaataag gagaaaccta tgtctcaata caagattgct ccgtcaattc
    13861 tggcagcaga ttatgccaac tttgaacgtg aaatcaaacg tctagaagca actggggcag
    13921 aatatgccca tatcgatatc atggacagtc attttgtacc gcaaatcagt tttggtgcag
    13981 gtgtggtcga gagccttcgt cctcatagta agatggtttt cgattgccac ttgatggtgt
    14041 caaaccctga gcatcatctg gaagattttg cgcgtgcagg tgcagacatc atcagtatcc
    14101 atgtagaagc aacacctcat attcatggcg ccctccaaaa aattcgttca ctcggagtta
    14161 agccttcagt cgttatcaat cctggcacac cagttgaagc catcaagcac gtccttcatc
    14221 tagttgacca agttttagtc atgacggtta atccaggttt tggtgggcaa gcctttctgc
    14281 cagaaaccat ggataaggtt cgtgagttgg ttgctcttcg tgaggaaaaa ggtttgaact
    14341 ttgaaatcga agtggatggt gggattgatg accaaactat tgctcaagcc aaagaagctg
    14401 gtgcgactgt ttttgtagca ggttcctatg tctttaaggg agaagtcaat gagcgagtac
    14461 aaactctcag aaaacaactg gactagggtt gcagtttttg caggcggaaa ccgcggtcat
    14521 tatcggacag attttgatgc ttttgttggg gtggatcgag gctcgctctg ggtcttggaa
    14581 gaagacttac ctcttgctct agcagtcgga gattttgatt ctgtgacgga agaagagcga
    14641 caggtgattc aaaaacgtgc ccagtatttt gtccaagccc gaccagaaaa ggatgataca
    14701 gatctggaat tggctctctt aaccatcttt gaacaaaatc ctcaggctca ggtcactatt
    14761 ttcggtgcct tgggtggccg tattgaccat atgttggcca atgtctttct acctagcaat
    14821 cctaagttgg caccctatat gcgtcaaata gaaattgagg atgggcaaaa tttgattgcc
    14881 tattgttcag aagggaccag tcagctagaa cctcgttcag actacgacta tctagccttt
    14941 atgccagttc gggatagcca gctgactatt cttggagcca agtatgagtt gacagaggaa
    15001 aattttttct ttaaaaaagt gtacgcttct aacgaatata tagataggga agtgtcggta
    15061 acttgcccag atggttatgt ggtcgtactg catagcaagg acaggaggta ggatggaaag
    15121 tttacttatt ctattattaa ttgccaacct agctggtctt tttctgattt ggcaaaggca
    15181 ggataggcag gagaaacact taagtaagag cttggaggat caggcagatc atttgtcaga
    15241 ccagttggat taccgctttg accaagccag acaagccagc cagttagacc aaaaagattt
    15301 ggaagtggct gtcagcgacc gtttgcaaga agtgcggatt gaattgcacc aaggcctgac
    15361 ccaagtccgt caagaaatga cagataatct cctccaaact agagacaaga cagaccaacg
    15421 tctccaagcc ttgcaggaat caaatgagca acgtttggaa caaatgcgcc agacggtcga
    15481 ggaaaaacta gaaaagacct tgcagacacg cttacaggct tcctttgaga cagtttctaa
    15541 acaactggag tctgtcaatc gtggtcttgg agaaatgcag acagttgccc gtgatgtcgg
    15601 agctcttaac aaggttctct ctggaaccaa gacgcgaggg attctgggag aattgcaact
    15661 ggggcaaatt attgaagaca tcatgacacc tgcccagtac gaacgagaat acgcaacggt
    15721 tgaaaactct agtgaacgag tggagtatgc catcaagtta cccggacaag gcgaccaaga
    15781 atacgtctac ctaccaattg actctaagtt tccactggca gattattacc gcttagaaga
    15841 agcctatgaa gtaggtgaca aggatgaaat cgaacgctgt cgtaagtcac tcctagcaag
    15901 tgtcaagcgt tttgctaggg atattaggaa caagtacata gcaccacctc ggacgaccaa
    15961 ttttggagtt ttgtttgttc cgacagaagg tctctactca gaaatcgtcc gcaatccggt
    16021 cttctttgat gatttgagac gggaagaaca gattatcgtt gcaggaccaa gtaccctatc
    16081 agcccttctt aactccctat cagttggttt caagaccctt aatatccaaa agagtgccga
    16141 ccatatcagc aagactcttg ccagtgtcaa gaccgagttt ggcaagtttg gtggtattct
    16201 ggtcaaggca caaaaacatc tccaacatgc ctctggcaat attgatgaat tattaaaccg
    16261 tcgtaccata gctatcgagc ggacgctccg tcacattgag ttgtcagaag gcgagcctgc
    16321 gcttgatcta ctccattttc aagaaaatga ggaagaatat gaagattagt cacatgaaaa
    16381 aagatgagct atttgaaggc ttttacctaa tcaaatcagc tgacctgagg caaactcgag
    16441 ctgggaaaaa ctacctagcc tttaccttcc aagatgatag tggcgagatt gatgggaagc
    16501 tctgggatgc ccaacctcat aacattgagg cctttaccgc aggtaaggtt gtccacatga
    16561 aaggacgccg agaagtttat aacaataccc ctcaagtcaa tcaaattact ctccgcctgc
    16621 ctcaagctgg tgaacccaat gacccagccg atttcaaggt caagtcacca gttgatgtca
    16681 aggaaattcg tgactacatg tcgcaaatga ttttcaaaat tgaaaatcct gtctggcaac
    16741 ggattgtccg aaatctctac accaagtatg ataaggaatt ctactcctat ccagctgcca
    16801 agaccaacca ccatgccttt gaaacgggct tggcttatca tacggcgacc atggtacgtt
    16861 tggcagacgc tattagcgaa gtttatcctc agctcaataa gagcttactc tatgcgggga
    16921 ttatgctgca tgacttagct aaggttatcg agttgacggg gccagaccag acagagtaca
    16981 cagtgcgagg taatcttctt ggacatatcg ctctcattga tagcgaaatt accaagacag
    17041 ttatggaact cggcatcgat gataccaagg aagaagtcgt tttgcttcgt catgtcatcc
    17101 tcagtcacca cggcttgctt gaatatggaa gtccagtccg tccacgtatt atggaggcag
    17161 agattatcca tatgattgac aatctggatg caagcatgat gatgatgtca acagctctgg
    17221 ctttggtgga taaaggagag atgtccaata aaatcttcgc tatggataat cgttccttct
    17281 ataaaccaga tttagattga taatttaaga aaaatgagca ttttttagga taagaatgtt
    17341 cgttttttta tgtgaatatg gtataataag taaaagacaa aaatgaatac tcttcgaaaa
    17401 tctcttcaaa ctagggtagt atcgctttgt cgtatgtata tatgcaggta tattacaggg
    17461 tttgtcagtt ctatcgacaa tctcaaaaca gtgttttgaa ccaccagcga ccagctttct
    17521 agtttgcttt ttgatttttt gaataaaaat ggaataggaa atagaaatga aattaagaag
    17581 aagtgatcgg atggttgtca tttccaacta tttgattaat aatccttata aactaactag
    17641 tctcaatact tttgctgaaa agtatgagtc tgctaaatca tccatctcag aagatatcgt
    17701 cattatcaaa cgcgcctttg aggaaattga aatcggtcat atccagacag tgactggggc
    17761 tggcggaggt gtcatcttca caccgtctat ttcgagtcag gatgctaagg aaatggttga
    17821 agacttgcgt accaagttgt cagaaagtga ccgtatcttg ccaggtggtt atatctatct
    17881 gtctgatttg cttagcacac cagccatctt gaaaaatatt ggtcgtatta ttgccaaaag
    17941 ctttatggac caaaaaattg acgcggttat gaccgtagca actaagggtg tgccacttgc
    18001 aaatgcagtt gccaatgtcc tcaatgtctc ttttgtcatt gtgcgccgtg acctgaaaat
    18061 taccgaaggt tcaactgtta gcgtcaacta tgtttcaggt tcaagtggtg accgtatcga
    18121 gaaaatgttc ctttcaaaac gtagtcttaa ggcaggcagc cgtgtcttga ttgtggatga
    18181 cttcttgaaa ggtggcggaa cggtcaacgg tatgattagt ctcttgcgcg agttcgactc
    18241 agaactggca ggtgtagcgg tctttgcgga caatgcccaa gaagaacgtg aaaagcagtt
    18301 tgactacaag tcactcttga aggtaactaa tattgatgtc aagaaccaag ccatcgatgt
    18361 tgaggttggc aatatctttg acgaagataa ataagagata gaactaaagg ttggaacgat
    18421 tgtcccagcc tttctttgca aacagaatag aaggaagctt atgaaaacac catttatcaa
    18481 tagagaagag ttagaagcga ttgttgccga gttcccgact ccctttcact tgtatgatga
    18541 gaaggggatt cgtgagaagg caagagccgt caaccaagct ttttcgtgga acaagggctt
    18601 taaggaatat tttgcagtta aggctactcc aactccagct attttgaaaa ttctccaaga
    18661 agaaggttgt ggtgtggact gctctagtta tgtagagctt ttgatgagcc ataaactgga
    18721 ctttctgggt tctgagatta tgttctcttc caacaacacg ccagacaagg aatacgccta
    18781 tgcacgtgaa ttgggtgcga ccattaactt ggatgccttt gaagatattg aacatctgga
    18841 gagagtagca ggcattccag aaatcatctc ttgtcgttat aatcctggag gcgtttttga
    18901 actggggaca gacattatgg acaatcctgg ggaggctaag tttggcatga ccaaggacca
    18961 gctctttgaa gcctttgcta tcttgaagga aaaaggagcc aagacttttg ggattcactc
    19021 cttcctagcg tccaataccg tgacccatct ctattatcca gagttggctc gtcagctctt
    19081 tgaactggct gttgaaatca aggaaaagtt gggcatttgg ctagacttta tcaatctttc
    19141 tggcggtatt ggtgttaatt atcgtccaga ccaggagccg aacgatatcg ccttgattgg
    19201 tgagggagtt cgtaaggtgt atgaagaagt tcttacgtca gcaggtcttg gtcaggtcaa
    19261 gattttcact gaattgggtc gttttatgct ggcacctcac ggtgctctag tcacaagagt
    19321 gactcataag aaggaaacct accgtaccta tctaggtgtg gatgcctcag cagtcaacct
    19381 catgcgtcca gctatgtacg gagcttacca tcatattagc aacgtgaccc atccagatgg
    19441 accagctgaa gcggtagatg tggttggttc actctgtgaa aacaatgata aatttgcagt
    19501 caatcgcgaa ctgcctcata cagaaatcgg tgatttgctg gtaattcatg atacaggtgc
    19561 ccacggattt tcaatgggct accagtataa tgccaaatta cgttctgcgg aaatcctcta
    19621 taccgaagaa ggtaaagccc gtcaaatccg ccgtgcagag cgccctgagg actattttgc
    19681 aaccttatat ggcttcgatt ttgaagaata atctgataat agattgaaaa tgaaattgaa
    19741 aaacagattg ctttctaaaa aataggcaaa aatcttgttt ttccttcaag tcgtgatata
    19801 ataaaactat aaaacgtttt caaggaaggt aacgatatgt ctgaagaaac aattgattat
    19861 ggacaagtga caggaatggt gcattcgaca gaaagctttg ggtcagtaga tgggcctggt
    19921 attcgcttta ttgtcttttt gcagggctgt cacatgcgtt gccagtattg ccacaaccca
    19981 gacacttggg ctatggagtc caataagtca cgtgaacgga cggtagatga tgtcttgaca
    20041 gaggccttgc gctaccgtgg tttctgggga aataagggtg ggattacagt cagtggagga
    20101 gaagctctct tgcagattga tttcctgatt gctctcttca ccaaggctaa ggaacaagga
    20161 atccactgta ccttggatac ctgtgctctt cctttccgta ataaaccacg ttaccttgag
    20221 aagtttgaca aactcatggc tgtcactgac ttggttcttt tggatatcaa ggaaatcaac
    20281 gaagaacagc acaagattgt cactagccaa actaataaaa atatcttggc ttgtgcccag
    20341 tatctatcag atattggaaa acctgtctgg attcgccacg tgctagttcc aggattgaca
    20401 gacagagatg atgacttgat tgaacttggt aagttcgtca agaccctcaa aaatgttgat
    20461 aagtttgaaa ttctacctta tcacactatg ggtgagttca agtggcgtga acttggaatt
    20521 ccatattccc tcgaaggagt caaaccacca acagcagatc gcgtcaagaa cgctaaacaa
    20581 ctcatggata ccgaaagtta tcaagattat atgaaacgtg tacatggata gaaaagaagc
    20641 ctgatggaaa catcgggctt ttgacttgca aaaagactta gcaaatcagc taagcctttt
    20701 tcttcttatc tcgaacgttg ttttccagcg ttgcgatttt tgtgtttttt cttgcttgtg
    20761 atagcagttg gttgttcagg ggtaacgtct tttcgtccac ttggtttaga gaaagcactt
    20821 gcttttggtg ggttcttggc tagttcttca cggacttttt tgcgaagttt tggacgaacg
    20881 atatagttga cgataaactg ttggagaatc atcatgaaac caccgacaac ccagtaaagt
    20941 gtgacactag ctggtgagaa gagggagaag acgacgatca tgagtgggct catgtaaatc
    21001 attttcttga tttgttctct ttgcatttca tcttctactc cgtgaagtga aaggagcgat
    21061 tgaagatagt aaaggacacc agcacaggca accaaaatca tacttggaga acctagagga
    21121 atgcctaggt agcttgcttg agcaacccct tcagtatgtt gggcagcaaa gtagatagca
    21181 gagaagaaag gcatttgaag gaggataggg aaacatccta caccaccaaa catgctgatg
    21241 ccgtgctctt tttgagcggc aaagagagct tgttgggctt cgagtttttc ttcttgagta
    21301 gttgcttctt tgagacgtgt ttggtgtggc tcaaggacat gcttgagagc gttcatcttt
    21361 tcagagtgaa gcgttgcctt ccatgattgg tagataccaa gtggtaagat aatcaagcgt
    21421 acgataatgg ttacgataat gatagcgaca ccaaagccta gacctttatc agtagcgaag
    21481 tatttgatgg cttcagccat aggcgctccg atcgtattcc aaataaatcc tgttggctga
    21541 cctgtggttt tatcgacatt gacacagcca gtcaagacaa gcaacatagc cactcccata
    21601 gccgagaatg caaaacgttt aatagatttc actgttttta ttccttcttt aaaaattata
    21661 cctttctatt ctactgtttt tttacaaaat atacaatagt tctggagacc taatttgcga
    21721 ttttaaagtc agagtaggga ggaaagttgc ttagtttgac atctaagtag cttacttttg
    21781 aaaaaggtgt cggtcctttt cggatttctt ggataaattt tgccatgata gcagatgagt
    21841 ctgcttgggc taagatttcc actgtgccat cgtcgttatt ccatactcga cctgtgatgc
    21901 caccaatttc aagtgccaag ctgtaaacac cccaacgaaa gccgactccc tgtaccctac
    21961 cttgggcaat cattctaacc ttttgcatac caaacccctt tgattgtgtt ataatatttc
    22021 tatgactatt ataacctcaa aagccaattc tgtggtaaaa aatgccaaga aattacgcca
    22081 aaaaaaatac cgcaagtctg cctatttgat tgaaggctgg cacttgtttg aagaagctgt
    22141 ccaagctgga gtgacgattg agaaaatctt tgccctagaa aattatcgag atcagttagc
    22201 tactttttcg caaactgtct gggtgtcaga ggatattttg ctagatttgg cggattctca
    22261 gactccacag ggaattgttg ccgtggttca aaaagaagaa gtaggacaag ctgatttgag
    22321 tcagggcaag ttcttgtttt tggaagatgt gcaagatcct ggtaatgtag gaactatcat
    22381 tcgaactgcg gatgcagcag gttttacagg agtgattgtt tcagataagt cggcagacat
    22441 ctacagtctc aaaaccctac gttccatgca aggtagtcat ttccatctgc ccatttaccg
    22501 gatgactagt caagcacttc ttgacgaaac taaaaaggta gctatcccag tgctagcaac
    22561 aaccctatct aaagattctg ttgattacag agaactgcct tctatagaaa attttgtact
    22621 agttatggga aatgagggtc aaggaattag tccccttatg gctgaaagtg cagaccagtt
    22681 ggtctatatt agcatgaagg ggcaggccga gagtttgaat gttgcggttg cagccggtat
    22741 tttaatcttc tatttaagct aattttaact ttttttgtta taatcaagga aagatgttca
    22801 cagaaaagga gaaatggatg aatcacacta ttatacatga ccgtgcaggt ctcaatcaat
    22861 tttacgctaa ggtttatgcc tttgttggtc tgggaatcgg actatctgct ttggtatcag
    22921 gccttatgtt gacggttttt cagtctcagt tggtttactt tttgatgcag gggcgtctct
    22981 ggttgaccat tgctactttt gcggagttgg ctttggtttt cgttgccagt agcatggctt
    23041 caagaaatag tccagctgct cttccagtat ttttacttta ctccgtttta aacggcttta
    23101 cccttagttt tgtggtggct ttctatactc cgggtacagt tttatctgcc tttgtatcga
    23161 gcgcccttct cttctttgtc atggcggcag ttggtatctt taccaagaaa gacttgagtg
    23221 ggattggtcg agcaatgatg gcagctctca ttggtttact gattgctatg gtagtcaata
    23281 ttttcttggc tagtggcttc tttgattata tgattagcgt agccatggtt ttggtttttt
    23341 cagggttgat tgcttgggat aaccaaaaga ttcgcctcgc ctatgaacaa tcacaaggtc
    23401 gtgtagcgac aggctgggtg gtgtcaatgg ctctcagcat ctatcttgat tttatcaatc
    23461 ttttcctaag tattctacgt atctttggtc gcaatgacta aaaggtctat gaaatcagtg
    23521 ttttgagtga cactgatttt ttttaaattt tctcttttct tttcttggaa ataggtgtat
    23581 aatacgttta ttaaattttt gaggagttgt ctatgaagaa aagttttatc catcaacaag
    23641 aagaaatttc ctttgtcaaa aacactttta cccagtattt gaaagataag ctagaagttg
    23701 tcgaagttca aggtcctatc ttgagtaagg tcggtgacgg aatgcaggac aacctgtctg
    23761 gtgtggaaaa tccagtatcg gtcaaggttc tccaaatccc tgatgctact tatgaagtgg
    23821 tgcactcact tgctaaatgg aaacgccaca ccttggctcg ttttggcttt ggtgaaggag
    23881 agggtctctt tgtccacatg aaagcccttc gtccagatga ggattccttg gatgcaaccc
    23941 actctgttta tgttgaccag tgggactggg agaaggttat cccaaatggt aagcgtaaca
    24001 tcgtttatct aaaagaaaca gttgagaaga tttataaggc tattcgcctg actgagctag
    24061 ctgttgaagc ccgctatgac atcgagtcta tcttgccaaa acaaattacc tttatccata
    24121 cagaagaatt ggtagaacgc tacccagact tgacaccgaa agaacgtgaa aatgcgattt
    24181 gtaaagaatt tggagccgtc tttttgattg gtatcggtgg cgagttgcca gatggtaaac
    24241 cgcacgatgg acgtgcacca gactatgatg actggacaag cgagtctgag aatggctaca
    24301 agggtctaaa tggtgatatt cttgtctgga atgagtcttt aggtggagcc tttgagttgt
    24361 cttctatggg aattcgtgta gatgaagaaa ctcttagacg tcaggtggaa attacaggtg
    24421 atgaagaccg cttggaattg gaatggcaca agtctttgtt gaatggtcta ttcccattga
    24481 caatcggtgg aggaattgga caatctcgta tggccatgtt cctacttcgc aagagacaca
    24541 tcggagaagt gcaaacaagt gtttggcctc aagaagtccg cgatacttac gaaaatattt
    24601 tgtagagaat cgaaccgcaa ggttcggttt tctttctctt tttgtctata atttggtata
    24661 ataaacagta tgaaaatcgt atcaggaatc tatgggggac gtcccctcaa gacactagaa
    24721 ggcaagacga caagacctac ttcggataag gttaggggag ccatttttaa catgattggt
    24781 ccctactttg aagtgggacg agtcttggac ctttatgcag gtagtggtgg tttatctatc
    24841 gaagcagtat cgcgtggcat gtccagtgct gttttggtgg agcgagaccg taaggctcag
    24901 accatcgtgg ctgaaaatat ccagatgacc aaggaagttg gaaaatttca actcctcaag
    24961 atggatgcag aaagggcatt ggaacaggta tctggggaat ttgacctcgt tttcttagac
    25021 cctccctatg ccaaggaaca aatcgtagca gatattgaaa aaatggctga gagagagctt
    25081 ttttctgaag atgttatggt tgtgtgcgag acggataaag ccgttgaact tccagaagaa
    25141 attgcctgtc tgggtatctg gaaggaaaag atttatggaa ttagtaaggt gacagtctat
    25201 gtcagataag attggcttat tcacaggctc atttgatccg atgacaaatg ggcatctgga
    25261 tatcattgaa cgggcgagca gactttttga taagctttat gtgggtattt tttttaatcc
    25321 ccacaaacaa ggatttctcc ctcttgaaaa tcgtaaacgg gggttagaaa aggctgtgaa
    25381 acatttggga aatgttaaag tcgtgtcttc tcatgataaa ttggtggtcg atgtcgcaaa
    25441 aagactgggg gctacttgcc tagtgcgagg cttgagaaat gcgtcggatt tgcaatatga
    25501 agccagtttt gattactaca atcatcagct gtcttctgat atagagacta tttatttaca
    25561 tagtcgacct gaacatctct atatcagttc atcaggcgtt agagagcttt tgaagtttgg
    25621 tcaggatatt gcctgctatg ttcccgagag tattttggag gaaataagaa atgaaaaaaa
    25681 agattagatg gcccttatac gtcattgcgg ccttgattgt gactttcttg gcatttgtag
    25741 tgcccttgcc ttattatata gaggttccag gtggttcgga agatattcgc caagtcctta
    25801 aagtaaatga cacagaagat aaggaagctg gtgcctatca attcgttacg gttggtgttc
    25861 aacatgccac tttagctcat atgatttatg cttggttgac accttttaca gatattcgta
    25921 gtgctcagga gactacaggt ggttcttccg atgttgaatt tatgcgaatc aatcaattct
    25981 acatgcaaac atcgcaaaat atggccaagt atcaaggact aaaaacagct ggtaaggata
    26041 tcgaactcaa gtactttgga gtttatgttt tgaatgtgac ggataattca acctttaaag
    26101 ggattctcaa tatctctgat acagtcacag cagtcaatga tcagaccttt gatagttcca
    26161 aagacttgat tgattacgtc agttctcaaa aattagggga ttccgtcaag gtcacctatg
    26221 aagaggatgg gcaaaccaag tctgcagaag gaaaaatcat caccttggaa aatggcaaaa
    26281 atggaattgg aatcggcttg attgaccgta cagaggtaat cagcaatgtc ccaattagct
    26341 tttcaacagc tggtattggc ggtccaagtg ctggtctcat gtttagtcta gctatctata
    26401 ctcaaatagc tcacccagat cttcgtaatg gtcgtattgt tgccggtaca ggtaccattg
    26461 accgcgatgg taatgtggga gacattggag gtattgataa gaaggttgta gcttcggcta
    26521 gggcaggtgc tgctattttc tttgctcctg ataaccctgt tagcgaagaa gaacaaaagg
    26581 cgcatccgga cgcgaaaaac aactaccaaa cagccctaga agcggctaaa acaatcaaga
    26641 cggatatgaa aatcgtgccc gttaaaaccc tacaagatgc gattgattac ttgaaaaaca
    26701 atccctaatt tttgagtgaa gtttccaaac tagcgcacaa acagagaaga tggtataata
    26761 gtcaaatggt tcaattatta ttcactctaa gtagtcatat gttctttatt tatgtgagtt
    26821 tttacctttt aaaggatctt gttagatggg agaaggtttt aaaagtgaca gatgataata
    26881 caagaaaagt tcgtttatta gtagcctttt ttagcattgt cataggctac atcctgagtt
    26941 ctttctttat tagcctgtat catttgtggc aagaagcgct tagaggatta ttatgaaatc
    27001 aagagtaaag gaaacgagta tggataaaat tgtggttcaa ggtggcgata atcgtctggt
    27061 aggaagcgtg acgatcgagg gagcaaaaaa tgcagtctta cccttgttgg cagcgactat
    27121 tctagcaagt gaaggaaaga ccgtcttgca gaatgttccg attttgtcgg atgtctttat
    27181 tatgaatcag gtagttggtg gtttgaatgc caaggttgac tttgatgagg aagctcatct
    27241 tgtcaaggtg gatgctactg gcgacatcac tgaggaagcc ccttacaagt atgtcagcaa
    27301 gatgcgcgcc tccatcgttg tattagggcc aatccttgcc cgtgtgggtc atgccaaggt
    27361 atccatgcca ggtggttgta cgattggtag ccgtcctatt gatcttcatt tgaaaggtct
    27421 ggaagctatg ggggttaaga ttagtcagac agctggttac atcgaagcca aggcagaacg
    27481 cttgcatggt gctcatatct atatggactt tccaagtgtt ggtgcaacgc agaacttgat
    27541 gatggcagcg actctggctg atggggtgac agtgattgag aatgctgcgc gtgagcctga
    27601 gattgttgac ttagccattc tccttaatga aatgggagcc aaggtcaaag gtgctggtac
    27661 agagactata accattactg gtgttgagaa acttcatggt acgactcaca atgtagtcca
    27721 agaccgtatc gaagcaggaa cctttatggt agctgctgcc atgactggtg gtgatgtctt
    27781 gattcgagac gctgtctggg agcacaaccg tcccttgatt gccaagttac ttgaaatggg
    27841 tgttgaagta attgaagaag acgaaggaat tcgtgttcgt tctcaactag aaaatctaaa
    27901 agctgttcat gtgaaaacct tgccccaccc aggatttcca acagatatgc aggctcaatt
    27961 tacagccttg atgacagttg caaaaggcga atcaaccatg gtggagacag ttttcgaaaa
    28021 tcgtttccaa cacctagaag agatgcgccg catgggcttg cattctgaga ttatccgtga
    28081 tacagctcgt attgttggtg gacagccttt gcagggagca gaagttcttt caactgacct
    28141 tcgtgccagt gcagccttga ttttgacagg tttggtagca cagggagaaa ctgtggtcgg
    28201 taaattggtt cacttggata gaggttacta cggtttccat gagaagttgg cgcagctagg
    28261 tgctaagatt cagcggattg aggcaagtga tgaagatgaa taagaaatca agctacgtag
    28321 tcaagcgttt acttttagtc atcatagtac tgattttagg tactctggct ctaggaatcg
    28381 gtttaatggt aggttatgga atcttgggca agggtcaaga tccatgggct atcctgtctc
    28441 cagcaaaatg gcaggaattg attcataaat ttacaggaaa ttaggctgga gaaccagcct
    28501 ttttctaaag ataaggagaa atatgaacaa aaaaacaaga cagacactaa tcggactgct
    28561 agtgttattg cttttgtcta cagggagcta ttatatcaag cagatgccgt cggcacctaa
    28621 tagtcccaaa accaatctta gtcagaaaaa acaagcgtct gaagctccta gtcaagcatt
    28681 ggcagagagt gtcttaacag acgcagtcaa gagtcaaata aaggggagtc tggagtggaa
    28741 tggctcaggt gcttttatcg tcaatggtaa taaaacaaat ctagatgcca aggtttcaag
    28801 taagccctac gctgacaata aaacaaagac agtgggcaag gaaactgttc caaccgtagc
    28861 taatgccctc ttgtctaagg ccactcgtca gtacaagaat cgtaaagaaa ctgggaatgg
    28921 ttcaacttct tggactcctc caggttggca tcaggtcaag aatctaaagg gctcttatac
    28981 ccatgcagtc gatagaggtc atttgttagg ctatgcctta atcggtggtt tggatggttt
    29041 tgatgcctca acaagcaatc ctaaaaacat tgctgttcag acagcctggg caaatcaggc
    29101 acaagccgag tattcgactg gtcaaaacta ctatgaaagc aaggtgcgta aagccttgga
    29161 ccaaaacaag cgtgtccgtt accgtgtaac cctttactac gcttcaaacg aggatttagt
    29221 tccctcagct tcacagattg aagccaagtc ttcggatgga gaattggaat tcaatgttct
    29281 agttcccaat gttcaaaagg gacttcaact ggattatcga actggagaag taactgtaac
    29341 tcagtaaaag ataagcctaa actcctatgt cacttatgga tgtaggagtt ctttttacta
    29401 gtttaagcag ggctagaaca ggtactaaga aaaaatagca acttctaaaa ctaacttcca
    29461 gtttcccaca acctagcttt tagtatgaga aaaacgcgtg aaatcagtgg aaatccgtct
    29521 tagactaact tccagttttg ggagagagat ggaagttacg ctaagaaaaa aataatatgt
    29581 attggattaa attttgtgat ataataaagg ataagatact attttaggag aagaactatg
    29641 gaagacccaa gtagtcagaa tttgttgcta caatttgttt tattgtttat cttgacggta
    29701 ttaaatgcct ttttctcagc cacagaaatg gccatggttt ctcttaatcg tgcccgagtt
    29761 gaacaaaagg cggaagaagg agacagacgc tacatccgcc tgctgaaggt actagaaaat
    29821 cctaatcact ttttatcaac cattcaggta ggaatcaccc tgattacaat cttatcaggg
    29881 gcgagtttaa ctaatactct aggacgtgtg attgcctctt ggcttgggaa tggcgaaaca
    29941 gcacaagccg tggcaacttt tctatccttg gcatttttga cctatatttc catcgttttt
    30001 ggggaattat atcctaagag aatcgctctt aatctaaagg atgccttggc aattcgtaca
    30061 gcgccggtta tcattgggat cggaaaacta gtcagtcctt ttgtttggct tttagctgct
    30121 tcgaccaatt tcttgagcca tttgactcct atgtcattcg atgatgcgga tgaaaagatg
    30181 acccgtgatg aaattgccta tatgctgaca aatagtgaag aaacattgga tgctgatgag
    30241 attgagatgc tacaaggtgt cttttcgctc gatgaactga tggcacgaga ggttatggtt
    30301 cctcgaacgg atgcctttat ggtggatatt caggatgata gtcaagccat tatccaaagt
    30361 attttaaaac aaaattattc tcgtatcccg gtttatgatg gggataagga caatgtaatt
    30421 ggaatcattc acaccaagag tctccttaag gcaggctttg tggacggttt tgacaatatt
    30481 gtttggaaga gaattttgca agatccactt tttgtacctg aaactatttt tgtggatgac
    30541 ttgctaaaag aactgcgaaa tacccaaaga caaatggcaa tcttgctgga tgaatacggt
    30601 ggtatggctg gtttggtgac tttggaagac ctcttagagg aaattgttgg tgaaattgat
    30661 gatgaaacgg acaaagcagc aatagatgtt catcagattg gcgaggatac ctacattgtt
    30721 caaggaacta tgaccctcaa tgatttcaat aattactttg atgttgaact ggaaagtgat
    30781 gacgttgata ccatcgctgg ttattatttg acaggagtgg gaactattcc aacgactgag
    30841 aaactcagct atgaattggt tagccaaaac aaacagttta tcttaaccaa tgataaagtg
    30901 aagaatggac gtgttaccaa ggtaaaagtc caaatcacag aagtcgaaat agaagaagaa
    30961 acagaataaa ctagaggctt ttgtcaccag gcgtgacgaa gcttttttca attgatttca
    31021 aaagggaatt atgccatgga aagaactctg ccacaaactc gctccaaaag tttttaaagt
    31081 tatacgtatt tattcgaggg aaaataaaaa aagcccttca aattgggctt tctgttcatt
    31141 tgaaacctga taaatcaagt tatagaaggc ggtagacgga tttgaaccga cgatcaagct
    31201 tttgcagagc cgtgccttac cacttggcta taccgcctta acgtttatta ttataccttg
    31261 aaaatgattt tcagtcaata gttttttcag ttttttgtac catagcgtga ttcgaatgtg
    31321 atgccaagtt ttctatggga aaaaatttac caaaaaccta ctgaaacccc ttgaaaaatc
    31381 tagctaaata gggtataata tgggtaatca tttgtcgtag gttttgtctg aaatattgtc
    31441 cagacaaggc tcacagcagt taaatcttct gaaaaagtca gatttagctg ctctttttgt
    31501 gctttttttc aagattatga gcatttgtaa cagaggctta aagattctga aaattcgtca
    31561 agaggacacg gtgataaggg gtttacaacc atatgacgat tagaaaagcc tgattgacaa
    31621 ggcttggaac ttatttacaa aggagaatca tcttggcagg acatgacgtt caatacggga
    31681 aacatcgtac ccgtcgtagt ttttcaagaa tcaaagaagt tcttgactta ccaaatttga
    31741 ttgaaattca aactgactca ttcaaagctt tcctagacca cggtcttaag gaagtgtttg
    31801 aagatgtatt gccaatttca aacttcacag acacaatgga gttggaattt gttggatatg
    31861 aaatcaagga accaaaatac acgctagaag aagctcgtat ccacgatgct agctactcag
    31921 caccaatttt tgtaaccttc cgtttgatca ataaagaaac aggcgaaatc aagacccaag
    31981 aagttttctt tggtgatttc ccaatcatga cagaaatggg tactttcatc atcaatggtg
    32041 gtgaacgtat tatcgtttct cagttggtcc gctcaccagg tgtttacttt aacgacaaag
    32101 tagacaaaaa tggtaaggtg ggctatggtt caactgttat ccctaaccgt ggagcttggt
    32161 tggaacttga aagcgactca aaagatatca cctacactcg tatcgaccgt actcgtaaga
    32221 ttccatttac aaccttggtt cgtgctcttg gtttctcagg tgatgatgaa atctttgata
    32281 tctttggtga cagcgaattg gttcgcaaca ctgttgaaaa agatatccac aagaatccaa
    32341 tggactctcg tacagacgaa gccttgaaag aaatttacga acgccttcgt ccaggtgagc
    32401 ctaagacagc tgaaagctca cgtagcttgc ttgtggctcg cttctttgac ccacgtcgct
    32461 atgacttggc agcagttggt cgttacaaaa tcaataaaaa actcaatgtt aaaacacgtt
    32521 tgctcaacca aaccattgca gagccattgg tagaccctga aactggagaa atcttggtag
    32581 aagctggtac gattatgact cgtagcgtga ttgaaagcat tgaaagccat ttggatggcg
    32641 acttgaacaa gattgtctac atcccaaacg atgcagccgt tgtgactgag cctgttgttc
    32701 ttcaaaaatt caaggttgtt gctccaactg atccagatcg cgtcgtaacg atcattggta
    32761 atgctaaccc agatgacaag gttcgtacgg tgactcctgc agatatcctt gctgagatga
    32821 gctacttcct caacttggct gaaggacttg gccgtgtaga tgatatcgac caccttggaa
    32881 atcgtcgtat ccgtgcggtt ggtgaattgc ttgccaacca agtacgtttg ggactttctc
    32941 gtatggaacg taatgtccgt gaacgtatgt ctgttcagga caatgaagtc ttgacaccac
    33001 aacaaattat caatatccgt cctgtaacag ctgcggttaa agaattcttt ggttcatcac
    33061 agttgtcaca gttcatggac caacacaacc cgctttctga gttgtctcac aaacgccgtt
    33121 tgtcagcctt aggacctggt ggtttgactc gtgaccgtgc cggatatgaa gtacgtgacg
    33181 tgcactacac tcactatggt cgtatgtgtc caatcgagac acctgaagga cctaacatcg
    33241 gtttgatcaa taacttgtca tcttacggac acttgaacaa atatggtttt gttcaaacac
    33301 cataccgtaa ggttgaccgt gaaacaggtg ttgtcacgaa cgaaattgtt tggttgacag
    33361 ctgatgaaga agatgaatat actgtagctc aggctaactc tcgtctgaat gaagatggaa
    33421 cctttgctga gaagattgtc atgggacgtc accaaggggt caaccaagag tatccagcta
    33481 atattgttga ctacatggac gtttcaccaa aacaggtagt tgccgttgcg acagcatgta
    33541 ttcctttctt ggaaaacgat gactccaacc gtgccctcat gggagccaat atgcaacgtc
    33601 aggctgtgcc attgattaat cctcaggcac cttacgttgg tactggtatg gaataccaag
    33661 cagcccacga ttctggtgcg gctgtgattg ctcagtatga tggtaaagtt acttacgcag
    33721 atgctgacaa ggtagaagtt cgtcgtgaag atggttcatt ggatgtttac cacatccaaa
    33781 aattccgtcg ttcaaactca ggtactgctt acaaccaacg cactctcgta aaagttggtg
    33841 atgtcgttga aaaaggcgat ttcatcgctg acggaccttc tatggaaaat ggagaaatgg
    33901 cgcttggaca aaacccaatc gttgcctaca tgacttggga aggttacaac ttcgaggatg
    33961 ccgttatcat gagcgaacgc ttggtgaagg acgatgtcta cacatctgtt caccttgaag
    34021 aatacgaatc agaaacgcgc gatacaaagc ttgggcctga agaaatcact cgcgaaattc
    34081 caaacgttgg tgaagatgcc ctcaaagacc ttgacgaaat ggggattatc cgtattggtg
    34141 ctgaggttaa agaaggtgat attcttgtag gtaaagtaac acctaagggt gagaaagatc
    34201 tttcagctga agaacgtctc ttgcacgcta tctttggaga caagtctcgt gaagtgcgtg
    34261 atacttctct tcgtgtacca cacggtgccg atggtgtcgt tcgtgatgtt aagatcttta
    34321 cacgtgtaaa tggagatgag ttgcaatcag gtgttaacat gttggttcgt gtttacatcg
    34381 ctcaaaaacg taagattaag gtcggagata aaatggccgg acgtcacgga aacaaagggg
    34441 ttgtctctcg tatcgttcct gtagaagaca tgccttacct tccagacgga actccagtcg
    34501 acatcatgtt gaacccactt ggggtgccat cacgtatgaa tatcggtcag gttatggagc
    34561 ttcaccttgg tatggcagct cgtactcttg gtattcacat tgcgacacca gtctttgatg
    34621 gagcaagttc tgaagatctt tggtcaactg ttaaagaagc aggtatggat agcgatgcca
    34681 agacaatcct ttacgatgga cgtacaggtg aaccatttga taaccgtgtt tctgttggag
    34741 tcatgtacat gatcaaactc caccacatgg ttgacgataa attgcacgcg cgttcagtcg
    34801 gaccttactc aactgttacc caacaaccac tcggaggtaa agctcagttt ggtggacaac
    34861 gtttcggtga gatggaggtt tgggctcttg aagcctacgg tgcgtcaaat gtccttcaag
    34921 aaatcttgac ttacaagtcg gacgatatca acggacgttt gaaagcctat gaagctatta
    34981 caaaaggcaa accaattcca aaaccaggtg ttccagaatc cttccgagtt cttgtcaaag
    35041 aattgcaatc tcttggtctt gacatgcgtg tcctagacga agatgaccaa gaagtggaac
    35101 ttcgcgactt ggatgaagga atggacgaag atgtcatcca cgtagatgac cttgaaaaag
    35161 cccgcgaaaa agcagcccaa gaggctaaag cagcctttga agctgaagaa gctgagaaag
    35221 caacaaaagc ggaagcaaca gaagaagctg ctgaacaaga ataagcagtt cacttagaat
    35281 agaaagggaa gaaatagtgg ttgatgtaaa tcgttttaaa agtatgcaaa tcaccctagc
    35341 ttctccaagt aaagtccgtt catggtctta tggagaagtc aaaaaacctg aaacaatcaa
    35401 ttaccgtacc ttgaaaccag aacgtgaagg actctttgat gaagtgatct ttggtcctac
    35461 aaaagactgg gaatgtgctt gtggtaagta caaacgcatt cgttacagag gaattgtttg
    35521 tgaccgctgt ggggttgaag taacgcgtac gaaagttcgt cgtgagcgta tgggacatat
    35581 cgaattgaaa gctcctgtat ctcacatctg gtacttcaag gggattccaa gccgtatggg
    35641 cttgaccctt gatatgagcc ctcgtgccct cgaggaagtt atctattttg cggcttatgt
    35701 ggtgattgat cctaaggata caccacttga gcacaagtct atcatgacag agcgcgaata
    35761 ccgagagcgc ttgcgcgaat atggttatgg ttcatttgtt gccaagatgg gtgcggaagc
    35821 catccaagac cttttgaagc aagtagatct tgaaaaagaa attgctgaac tcaaagaaga
    35881 attgaaaaca gctactggac aaaaacgtgt caaagccatc cgtcgtttgg atgttttgga
    35941 tgccttttac aagtctggaa acaaacctga atggatgatt cttaacatcc ttccggttat
    36001 cccaccagat cttcgtccaa tgttgcagtt ggatggtggc cgttttgcct catctgactt
    36061 gaatgacctt taccgccgtg ttatcaaccg taacaaccgt ttggctcgtt tgcttgagtt
    36121 aaatgcacca ggtatcatcg ttcaaaatga gaagcgtatg cttcaagaag cagttgacgc
    36181 tttgattgac aatggtcgtc gtggtcgtcc aatcacagga ccaggtagcc gtccattgaa
    36241 atcattgagc cacatgctta aaggtaaaca aggacgcttc cgtcaaaact tgctcggtaa
    36301 acgtgttgac ttctcaggac gttccgttat cgccgttggt ccaactctta agatgtacca
    36361 atgtggtgtg ccacgtgaaa tggcgattga actctttaaa ccatttgtta tgcgtgaaat
    36421 cgttgcccgt gatatcgtgc aaaacgtcaa agcagctaaa cgcttggtgg aacgcggaga
    36481 tgagcgtatc tgggatatcc ttgaagaagt gattaaagaa cacccagtgc ttttgaaccg
    36541 cgcaccgacc cttcaccgtt tgggtatcca agccttcgag ccagtcttga ttgatggtaa
    36601 ggctcttcgc ttgcacccac ttgtctgtga agcctacaat gctgactttg acggggacca
    36661 aatggccatc cacgtaccac tttcagaaga agcacaagca gaagctcgta tcctcatgct
    36721 agctgctgag cacatcttga acccgaaaga tgggaaaccg gtagttactc catctcagga
    36781 catggttttg ggtaactact acttgaccat ggaagaagct ggtcgcgaag gtgaaggaat
    36841 ggtcttcaaa gaccgtgacg aagcggttat ggcttaccgc aatggttatg ttcacctcca
    36901 ctcacgtgtt ggtatcgcaa cagacagcct caacaagcct tggacagaag agcaaagaca
    36961 taaggtcttg cttacaacag ttggtaaaat tctcttcaac gatatcatgc cagaggggct
    37021 accatacttg caagaaccaa acaatgccaa cttgacagaa ggtgttccag ctaaatactt
    37081 cttgccactt ggtggagata tcaaggaagc tatcagcaat cttgagctca accctccatt
    37141 caagaagaaa aacctcggaa atatcatcgc tgaaatcttc aaacgtttcc gtacgacaga
    37201 aacttctgcc ctacttgacc gcatgaagaa cctcggttac caccactcaa ctcttgcagg
    37261 attgacagtg ggtattgccg atatcccagt cgttgatgac aaggctgaaa tcattgaaga
    37321 atcacacaaa cgtgtcgaac aaatcaccaa acaattccgt cgtggtatga tcacagacga
    37381 cgagcgttac aatgctgtta cagctgaatg gcgtgctgcc cgtgaaaaac ttgagaaacg
    37441 cttgattgct aatcaagatc ctaaaaaccc aatcgttatg atgatggact ctggagcccg
    37501 tggtaacatc tcaaacttct cacagcttgc cggtatgcgt ggtctgatgg ctgctccgaa
    37561 tggacgtatc atggaattgc caattctttc aaacttccgc gaaggtttgt cggtattgga
    37621 aatgttcttc tcaactcacg gtgctcgtaa aggtatgacc gatacggccc ttaagacagc
    37681 cgactcaggt tacttgactc gtcgtttggt cgacgttgcc caagacgtta tcattcgtga
    37741 ggacgactgt ggaactgacc gtggtctctt gatccgttct atcgcagaag gaaaagagat
    37801 gatcgagtct ctcgaagagc gtctcaacgg tcgttacact aagaaaactg ttaaacatcc
    37861 agaaactggt gcagtgatta ttggtccaaa tgaattgatt acagaagaca aggcgcgtga
    37921 aattgtcaat gctggtgtgg aagaagtgac tatccgttct gtatttacat gtaacactcg
    37981 tcacggtgtc tgccgtcact gttacggtat caacttggcg actggtgatg cggttgaagt
    38041 tggtgaagca gttggtacaa ttgctgccca atctatcggg gaacctggta cacagcttac
    38101 aatgcgtacc ttccacacag gtggggttgc ctcaaatacc gatatcactc agggtcttcc
    38161 tcgtgtccaa gaaatctttg aagcccgtaa tcctaaaggg gaagcggtta tcacagaggt
    38221 taaaggacaa gttactgcta tcgaagaaga tgcatcaact cgtaccaaga aagtctttgt
    38281 taagggtgaa actggcgaag gtgaatatgt cgttccattt acagctcgta tgcgtgtcga
    38341 agttgggggc caagtagcgc gtggtgctgc tctgacagaa ggttctatcc aaccaaaacg
    38401 tctccttgca gttcgtgatg tcttgtcagt tgaaacgtac cttctcggtg aagtacaaaa
    38461 agtttaccgt agccaagggg tagaaatcgg tgacaaacac atcgaggtaa tggttcgtca
    38521 aatgatccgt aaagtccgtg tcatggatcc aggtgataca gatcttctca tgggtaccct
    38581 catggatatc aatgacttta cagatgccaa caaagatgtc cttatcgcag gtggagttcc
    38641 agcgacaggt cgcccagtcc ttatgggaat taccaaagct tcacttgaaa caaacagttt
    38701 cttgtcagcg gcttccttcc aggaaacaac tcgtgtcctt actgacgcag ctatccgtgg
    38761 taagaaagac catctccttg gacttaaaga aaatgttatc atcggtaaga tcatcccagc
    38821 tggtactggt atggcccgtt accgtaacct tgaaccacat gctgtcaacg aagaagaata
    38881 ccttaatcct ccagtagagg aagaaggaaa tgaagaaaca acagaagtag ttgtggatac
    38941 tgccgttgaa actgtggaag aaacagtaga ataagagaga atgagagaac ctgagggttc
    39001 tctcattctc tcttctgaaa actttctcca tttttccacg aaatgtggta aaataaaaga
    39061 aagaagctga caaaggagac gggtatggaa caaacattct ttatcatcaa accagatggt
    39121 gtaaaaagag ggctagtggg tgaagtgtta aagcgcatcg aacaacgtgg atttacaatc
    39181 gaaaaattgg agtttcgttc acaggtttca gaagagttga ttgaccagca ctatcaggac
    39241 ttggttggtc agagttttta cctaccgatt cgtgaattca tgacttcagg tccagttctt
    39301 gtgggtgtca tttctggtcc caaagtaatc gaaacttggc ggaccatgat gggtgcaact
    39361 cgtccagaag aagctttacc aggcactatt cgaggtgact ttgcaaaagc tgctggagaa
    39421 aatgagatta tccaaaatgt tgtacatggt tcagattcag aagagtcagc taagcgagaa
    39481 attgctcttt ggttttaaga gtggattggc tcaatcaatt ggttaaaagc tcatttgaat
    39541 agaaagtata gtcaattagt ttaagacatg acgcatgata tcaaactttt tagtttttga
    39601 tatggtgcgt tttttgatta agtgactatt agtttgtctc gctccgtgag gtgcgagaca
    39661 aaaaaaacac ccgctattgc gggtgcgcgt cgaaggttat accaaaaaaa ctccaaacgc
    39721 gatacaataa aggtgttcaa gccaattgta aagcgaaagg agaaaaatat ggcacaaaag
    39781 gttcttttgt cctgttcttg tttcaattga ctatatttct atactttttc ttcctttctt
    39841 tgtgaaaatc gcaagttttt cccacctttt ctcaatactg aaacaacatc tttccagaac
    39901 ttcaataatt tctttttgtg ttaaatcatt atttaactaa atctttggag gcaatacgtt
    39961 ttcaaagcta cttttttacc ataggttttg agccttcaac acagattact aagccaaaaa
    40021 tgctctaaat ttttgaaatt ctaacaaatt ccactcaact ttatcatcat ctttgacttt
    40081 cacaatatct tcctcaaaat aacatggaat aaagatagtt ttcttttaaa acggttgtag
    40141 gaggaaaatc tctcctacac tattattgat tctgagagaa aattgcaaaa tatcatctac
    40201 caaactttca attattaaga ttttttgcag tttatctgaa ttagaatcgc aaggcttctc
    40261 aataatataa ttgtcgaatt ttttcattct aacttcctct ccattatttc ttcctttatc
    40321 aagaaaaagt tacctcaata ttaataaagt acaattctaa attaactcca attcttgatt
    40381 catgataata tttcagtaac tcatcgtgca attaaaaaca aggattttta tttcagatga
    40441 tccatcgtga acacttcatc agccatctcc caaattgccg gattatgtgt tgcgataatg
    40501 attagcctat tatcatctcg aagagatagc aaaatctcca taatcaactg agaggttgct
    40561 gggtctattg aagctgttgg ctcatctgcc agaataaagg gtggattctt taagataatt
    40621 tttgccaagg caacccgttg cgattctccg cccgataact caaagatgcg cttatctagg
    40681 tcaagataag ccaggccgac ctgttctaaa gcctgcttct gcctcaaccg ctgttccgac
    40741 cgactcaact tttgaccaat gagacctagc ttaaggtttt cttcaatact ttggttttca
    40801 attaagccaa agttctggaa gaggtaaccc aattcgtgac ggaaaaaatc actcgattta
    40861 taattggcca agtctttacc tcggtaaaaa atcgtcccat cataaggttc taatttccca
    40921 atcatgttca tcaaggttgt ttttccgcta ccacttgaac caattaaggc atagactttt
    40981 ccagcctcaa atgtcattga aagattcgaa aataactctc gttctccaaa agatttactc
    41041 acctgtttaa gttcaatcat attaacctcc cttcaaaaca agaatggaca tcttgttttc
    41101 tttctgcatt tggacatgta actgtaaaag agatagacca gtaaagagta acaagactaa
    41161 gaaagcaact cctatctcta cctgaagaaa tacactcgca acaaatccca gtaaaaacac
    41221 acccagttga gcaaagagat aagtgcgatg gatttctaag aacctgagac ctgcaatgcg
    41281 tttgataaaa atggcacgtc taaattcttc aaagtagagc ctattcatag tgttaaacag
    41341 caagattgaa gttgcaatcc caagcacagc tcctgctagc attacccaac gttccctctg
    41401 gatattatcc aataatgtga tgtagttgtg gtaacctgtt tgcatttctg agacccaatt
    41461 ttcaatgcct tgtctctgga taagctcctg ggcatcagac aattgattaa agagaacgta
    41521 gttctgtact gcgtctatcc aaaacaaaat ggactgtgga ccagttgatt ggggtgttat
    41581 aacaatgatg attggatctt tcaaaaactg ctggtaagaa ataggggtcg tattatacac
    41641 aaaacgatcc tgacctgatt ctaaataacc taccgtagca gtcatttgct gtcgttcatc
    41701 ttgactagac atgcgactgg ttaagtcgtc ttcaaaaaca gatttataat gttcttcctc
    41761 tgaacggagg tgttcaggca gcaataagac aaactcccct acatcaaggt gattcatctt
    41821 ttgctcaata gttgtatcta caggaatgtt ttgacgctcc aagtattgcg gtgtgacgat
    41881 aaggacattg ccattcgggt tgtaatcgtg ccattctgta gaggttatca agtttttgga
    41941 ggaagccatg ccattttgca aagtacggtc aattaactgg tgtctagata agaaagcctt
    42001 ttgttctgaa acagccagat ccatcaattg ataccaagtt ctgagtttcc tttgagcttg
    42061 ttcatcaaaa ccaggactcg ttccttcacg gctgattgat agggtaatca gttgcctttc
    42121 ctggctccaa gcctcttgtc caatccgatg ctgttgccag gcttgggaat actttaagct
    42181 actccctatt cccagcgtta caataataat cgctaatagt tgaccgatta aaatcaaact
    42241 aatgattcct ctgacaggca cttgcccttt tataatctgc atcaggtgta tcttttttat
    42301 cccaactgcg aagagttgag cgaaaaacag ggagatagac aacaagatga gattataact
    42361 gagcaagcct gctcctatgg tcattaggga ttgcgttgga agcgacagaa ttttttgcat
    42421 aagaatggtg agcacgccag ctaaactgaa accaacagct atccctttca aatcatcacc
    42481 aactggtcta agaaaaatgg accaccgttt ctctcctgaa atgaggcgaa tgcccgacga
    42541 ccgtaattgg ctaatttgac taattaaagt cagtgctcca aaggttaaga tgaaaatcaa
    42601 tagactgatt aactgaaatc cgttactaaa gatagccatt aacgtagata gtttagatgg
    42661 aattgtcagg tgcatattag tcaagccaag ttgacttagc tcctccctta gcaagtgaat
    42721 atctaggtgt ccatcgaata caaaatagtt tgtttcaaca ctactacttt gagcatcttc
    42781 tagttttttt tcctgtagcc cgtcaggcaa ctttccgtct ccaaaggtcg tataagaaaa
    42841 aactgtagta ccttctgagt taggatcttg gtgttgaatc gcaataaagc tatctgtttc
    42901 ttctgctagt ttttccaagc gtgtagcaac atgctgaaaa gttgtttcag gggaagaatc
    42961 atgtacaaca acgttggggt aataatggga gacatatgta tcagtccaaa tggtaaatac
    43021 ccaaacaaag aacaaactag caagcaggtt ggatatgagt ataaataatt ttttcatagt
    43081 gcattcctta ttctaaaaca gagggcagaa atacccctgc cctctataaa ctaacaagct
    43141 tactaatatc tatctggtat tgttacaagc tctcatcaga atacctttct ctaaatagtt
    43201 gaattttaaa gtaatacgaa atcaatcagc cttcccaaca tcaagaccat tggacttctt
    43261 ttgcgattgc actcgaatct ccaattgtct attcttctga ataaactgtt ggtaaggaat
    43321 tgtattacta aacataaaaa tacctagtaa tactaatata gctaattttt gaattccacg
    43381 atttttcttc attcgtgaaa cccttttctt tttcattatc cttattttaa cagatatatt
    43441 ttatttagcc aagcattttt atgtaatttt tgactttttt tagtttatta ccataaagaa
    43501 ttatttattc ctttaacttg ctattttgaa ctaaaaattt tataatgcaa ttaagcaaat
    43561 aggaaggttt attatcttta atgaatacat tcgcagagaa attcagattg aaaagaaaag
    43621 agttgagact ctcccaacaa actcttgcag aaggaatttg tgaacaaagt cagattagta
    43681 aaattgagag agggcatttc attccctccg cagacctttt gttcaaactc tctcaacgac
    43741 ttgaagtacc attagattat ttttttaatg aacaaattga aattaaatct aacctctcta
    43801 atttcaagca attgtctgct cgactattag acgatagaaa ttatgacgat ttggaatata
    43861 tttatagaat agagattgaa cgaagtactt ttctaacact agaagaccga acttaccttg
    43921 aatggattaa agctattatt gccttctatc aatatgacag taagtgtgag gcaatttctt
    43981 cattggaaaa tatattatta aaagtctctt caaatactct gatttattta aaggcgttga
    44041 atactctatc taatttctat tccttagtgg gtcgtgaaca agaatatgag gcaaactact
    44101 ctcatttaat agagttgtat cagacaaaaa atttggacca tcaagagttt ttatttggct
    44161 acatcagagt tcgttacaac tacgctcact acctagtatc aaaggaaaaa tataatgaag
    44221 ccatccaaga agctcttgaa acgattgaac tctgtaaaca aagacagaca agctaccaat
    44281 tggctcctct acttattctt gtaggaaatg ctggagccaa atttctagac agagaacaag
    44341 tcaaaaatta ttatatagaa gcaagagagc tatgcaagat ttataacaat cctttaatgc
    44401 tgatgaagat agaaaattat ttgaaggaac tagatgctgt ttagtttatc ttgatattgg
    44461 agtgttactt aaacattaaa tagcctgtaa ggctgatagt tagattaata ctatcagcct
    44521 tataattatg tgactctgag tccgtctcgc tccgtgaggt gcgagacaaa acaaccaccc
    44581 gtttgacgga ttttcatgat ttcaaattta tattcttcga aaatctcttc aaaccacgtc
    44641 agctctatct gcaatctcaa aacagtgttt tgagcaacct gtggctagct acctagtttg
    44701 ctctttgatt ttcattgagt attagtctct agtgtttgtt tagcgtctta aagagacatt
    44761 tgagaagatt agaaacagtt ctctcttttc tcctagtata atgattggta ggaagggaga
    44821 gagaagatga aatcaatgag aatcttattt ttgttagctt taattcaaat cagtttgagt
    44881 agctgtttcc tatggaagga atgcatcttg tcctttaaac aaagtacagc ttttttcatc
    44941 ggaagcatgg ttttcgtttc aggaatctgt gctggagtaa attatcttta tacccgtaag
    45001 caagaagtcc atagtgtcct agccagtaag aagtcggtga agctttttta cagtatgtta
    45061 ctcttaatta atttgttagg agctgttctt gttttgtcag ataacttgtt catcaaaaat
    45121 acgctgcagc aagaattagt tgacttttta ttgccatcct tctttttcct atttgggcta
    45181 gatttgctga tttttttacc cttgaaaaaa tacgtgcgcg attttcttgc tatgctggac
    45241 agaaaaaaga cagtgttggt gactatttta gcaacacttc ttttcttaag aaatccaatg
    45301 accattgtct cacttctgat ttatattgga ctgggcttgt tttttgcagc ctatcttgtc
    45361 ccaaattcgg ttaagaagga agtttccttt tatggtcata ttttccgaga tcttgtattg
    45421 gtcattgtta cgctcatttt cttttagaga aagcctgttt tttatggatg ttatgatgat
    45481 aagtttagta ggaaaataga cacaaaagaa aagtttttgg tataataaga gtatgtacac
    45541 aaaaaatgaa gaagagttgc aagccttagg ggagcgtttg ggccatctat tagcaaagaa
    45601 tgatgtttta atcttaactg gagaactggg tgcaggtaaa acgaccttta ctaaaggact
    45661 tgcaaaagga ttacagattt ctcaaatgat taaaagtccc acctatacta tcgtgagaga
    45721 gtatgaaggt cgacttccac tttatcacct agatgtttat cgtattgaag gagatgctga
    45781 ttctatcgac ttggatgagt ttatctttgg tggcggcgtg actgttattg agtggggaaa
    45841 tctcttagga gatgccttgc cagatgctta tttagaattg gaaattctaa aagaagcaga
    45901 tggacgccgt ttaaattttc aggcaaaggg tttgcgtgct gagaaattgt tagaggagct
    45961 tcaatatgga gtatgaattg ctcattaggg aagcagagcc caaagatgca gctgaattag
    46021 tggccttttt aaatcgtgtg agtttggaga cagactttac cagcctagac ggagatggta
    46081 ttctcttgac tagtgaggag atggaaatat tcctcaacaa gcaagctagt tcggacaatc
    46141 agataacctt acttgcattc ttaaatggca aaattgctgg tattgtaaat attacagctg
    46201 atcagcgtaa gagagtccgt catattggag atctcttcat tgtgattgga aaaagatatt
    46261 ggaataatgg cttgggaagt ttgttgctag aagaagcgat agagtgggca caagcaagtg
    46321 gcattctgcg tcgtctccaa ctgactgtcc aaactcgtaa tcaagcagca gtccatcttt
    46381 atcaaaagca tggctttgtc attgaaggta gccaagagcg tggggcatat atagaagaag
    46441 ggaaatttat cgatgtttac ttgatgggta aactgatagg ttagtagaaa tatggttaaa
    46501 aaaattattg gaatggtgct agctttactt tctgtaactg tagtaggagt aggtgttttt
    46561 gcttatacta tttatcaaca agggacagaa accttagcta aaacctataa aaaaatcggc
    46621 gaagaaacca aggttattga agcgactgaa cctctaacca ttctgttaat gggagtggac
    46681 accggaaatg ctgaacgaac tgaaacttgg gtcggtagaa gtgatagcat gatcttgatg
    46741 acagtgaatc ctaaaacgaa aaaaacaaca atgatgagtt tagagcggga tattctgacg
    46801 cgcattgaat cagggaatgg tcaggctcat gaagcgaaac tgaactcagc atatgcagat
    46861 ggtggagcag agcttgctat agaaaccatt caaaaaatga tgaatatcca tattgatcgc
    46921 tatgtgatgg tcaatatgag agggttgcaa aaactagtgg atgcagtagg aggtattaca
    46981 gtcaataata tcctaggttt cccaatttct atcagtgacc aagaagaatt taatactatt
    47041 tctatcggtg ttggggagca acatattgga ggagaagaag ccctagtcta tgcacgaatg
    47101 cgttaccaag atcctgaggg ggattatggt cgtcaaaaac gtcaacgtga agttattcaa
    47161 aaagtcatgg aaaaagctct cagtttaaat agcgttggtc attatcaaga gattctaaaa
    47221 gctttgagtg acaatatgca gaccaatatt gatttgtctg caaaaagtat ccctaacttg
    47281 ctaggctata aagattcatt taaaaccatt gaaactcagc agttgcaggg tgaaggagag
    47341 atacttcaag gtgtttctta ccagattgtt tcgagagcac atatgttgga aatgcaaaat
    47401 atactccgac gttctttggg acaagaagaa gttactcagc ttgaaaccaa tgcggtttta
    47461 tttgaagatt tatttggcag agcacctgtt ggtgatgaag ataattaact tttgatacaa
    47521 ataaaaaaat caatcgtagg aaaattcctg cgattttttc aaaaaaatac gaatagatag
    47581 gtaggaggaa acatgaaagc agaaatcatt gctgttggaa cagagatttt gacaggacag
    47641 attgtcaaca ccaatgctca gtttttgtcg gaaaaactag ctgagattgg ggtagatgta
    47701 tattttcaga cggctgtagg agacaatgaa gttcgtctct tgtctttgct tgagattgcc
    47761 agtcaacgta gcagtctggt gattttgaca ggcggtttgg ggccaactga ggacgaccta
    47821 accaaacaaa ccctagctaa atttttaggg aaagcattag tctttgatcc tcaggctcag
    47881 gagaagttgg atatcttttt tgccctgcga ccagactatg cccgaacacc gaataacgaa
    47941 agacaagctc aaattgtaga aggagcgatt ccactgccaa acgaaacagg actggctgtt
    48001 ggaggaaaat tagaagtaga cggagtgacc tatgtcgtcc ttccaggtcc gccaagtgaa
    48061 ttgaaaccca tggtcttaaa ccgacttcta cccaagttga tgacagggag caagctgtat
    48121 tcccgagttc ttcgtttctt tgggattggc gagagccagt tggttacgat tttggctgat
    48181 ttaattgata atcagatcga tcctaccttg gccccttatg ccaagacagg agaagtcact
    48241 ctacgtctgt caacaaaggc tagcagtcaa gaagaggcga atcaagcgct ggatatcttg
    48301 gaaaatcaaa tcttggactg ccagactttc gaaggaattt ctttacgaga cttttgctat
    48361 ggttatgggg aagaaactag tttagccagc attgtggtag aagaactgaa aaggcaaggg
    48421 aaaaccatcg cggctgcaga gagtttgacg gcaggtcttt tccaagctac cgtggcgaat
    48481 ttttctggag tttcaagtat atttgagggt ggttttgtga cctatagctt ggaggaaaaa
    48541 tcaaggatgt tggatattcc tgccaagaat ttggaagaac atggtgtggt gtctgaattt
    48601 acagctcaga agatggctga gcaggcacga agcaagaccc agtctgattt tggaattagt
    48661 ttgactggag tggcaggacc agatagccta gaaggacacc cagttgggac agtcttcata
    48721 ggcttggcgc aagatcaagg aactgaggtt atcaaggtta atattggagg cagaagccga
    48781 gcagatgtac gtcacattgc ggttatgcat gcctttaacc tagttcgcaa ggctttatta
    48841 agtgactaac ttttgatata atagtagata ggtctgagga tcattagaat gtaggagaat
    48901 agaatggcga aaaaaccaaa aaaattagaa gaaatttcaa aaaaatttgg ggcagaacgt
    48961 gaaaaggcct tgaatgacgc tcttaaattg attgagaaag actttggtaa aggatcaatc
    49021 atgcgtttgg gtgaacgtgc ggagcaaaag gtgcaagtga tgagctcagg ttctttagct
    49081 cttgacattg cccttggctc aggtggttat cctaagggac gtatcatcga aatctatggc
    49141 ccagagtcat ctggtaagac aacggttgcc cttcatgcag ttgcacaagc gcaaaaagaa
    49201 ggtgggattg ctgcctttat cgatgcggaa catgcccttg atccagctta tgctgcggcc
    49261 cttggtgtca atattgacga attgctcttg tctcaaccag actcaggaga gcaaggtctt
    49321 gagattgcgg gaaaattgat tgactcaggt gcagttgatc ttgttgtagt cgactcagtt
    49381 gctgcccttg ttcctcgtgc ggaaattgat ggagatatcg gagatagcca tgttggtttg
    49441 caggctcgta tgatgagcca ggccatgcgt aaacttggcg cctctatcaa taaaaccaaa
    49501 acaattgcca tttttatcaa ccaattgcgt gaaaaagttg gagtgatgtt tggaaatcca
    49561 gaaacaacac cgggcggacg tgctttgaaa ttctatgctt cagtccgctt ggatgttcgt
    49621 ggtaatacac aaattaaggg aactggtgac caaaaagaaa ccaatgtcgg taaagaaact
    49681 aagattaagg ttgtaaaaaa taaggtagct ccaccgttta aggaagccgt agttgaaatt
    49741 atgtacggag aaggaatttc taagactggt gagcttttga agattgcaag cgatttggat
    49801 attatcaaaa aagcaggggc ttggtattct tacaaagatg aaaaaattgg gcaaggttct
    49861 gagaatgcta agaaatactt ggcagagcac ccagaaatct ttgatgaaat tgataagcaa
    49921 gtccgttcta aatttggctt gattgatgga gaagaagttt cagaacaaga tactgaaaac
    49981 aaaaaagatg agccaaagaa agaagaagca gtgaatgaag aagttacgct tgacttaggc
    50041 gatgaacttg aaatcgaaat tgaagaataa gctgttaaag cagtggaaaa atccgctact
    50101 ttttcgattt ttgattcaag tttttagatt atatatagta gcttgaaata agatatgaac
    50161 aactttatta ggaaagtcaa attaatttct agaaatgttt tagcagctac agcgtactat
    50221 tccaaactca accaactata atagatcgaa actagaatag tacacatcta cttctaaaac
    50281 attgttaaaa atcgatttga ctgtccttat ttcattccgc tatatataag tttgctgttt
    50341 cttgtcgctc ctctggaaag ctgatataat agctttatga ataaaaaacg aacagtggac
    50401 ctgatacatg gttcgattct tccctcgctc ttaagcttca cctttccaat cttgctatca
    50461 aatatttttc aacagctcta taacactgct gatgtcttga ttgttggacg atttcttggt
    50521 caagaatcct tggctgcagt aggagcgacg acagcgattt ttgacctgat tgtaggtttt
    50581 acacttggtg ttggcaatgg catggggatt gtcattgctc gttattatgg ggctcggaat
    50641 ttcactaaaa tcaaggaagc agtagcagcc acctggattt taggtgctct tttgagcatt
    50701 ctagttatgt tgctgggctt tcttggcttg tatcctctct tgcaatactt agatactcct
    50761 gcagaaattc ttcctcaatc ttatcaatat atttctatga ttgtgacctg tgtaggtgtc
    50821 agctttgctt ataatctttt tgcaggcttg ttgcggtcta ttggtgacag tctagcagcc
    50881 ctgggatttc tgattttctc tgccttggtt aatgtggttc tggatctcta ttttattacg
    50941 caattgcatc tgggagttca atccgcagga cttgctacca ttatttcgca aggtttatca
    51001 gcggttctct gcttttatta tattcgtaaa agtgtgccag aactcttgcc acggtttaaa
    51061 catttcaaat gggacaaaag cttgtacgcg gatctcttgg agcaaggttt ggctatgggc
    51121 ttgatgagtt caattgtatc tatcggcagt gtgattttac agttttctgt taatacattt
    51181 ggtgcagtga ttattagtgc ccagacggca gctcgacgca ttatgacctt tgcccttctt
    51241 cctatgaccg ctatttctgc atcaatgacg acctttgctt ctcagaatct aggagctaag
    51301 cgacctgacc gcattgttca aggtcttcga atcggcagtc gtttaagtat atcctgggca
    51361 gtttttgttt gtattttcct cttttttgcc agtccagcct tggtttcctt cttggctagt
    51421 tcgacagatg gttacttgat agaaaatgga agtctctatc tgcaaatcag ttcagccttt
    51481 tatcccattt tgagcctctt gttgatttat cgcaattgct tgcagggctt gggacagaag
    51541 atccttcctc tagtttctag ctttattgaa ctaatcggaa aaatcgtttt tgtggttttg
    51601 attattcctt gggcaggata taagggtgtt atcctttgtg aacctcttat ctgggttgcc
    51661 atgacagttc aactgtactt ctcactattc cgtcatccct tgataaaaga aggaaaggca
    51721 attttggcaa ccaaagtgca atcctagttg gatttactga ataaaatcca tttcctctag
    51781 tgaaaatcga aaaaacttgt gttctcttct ttagtttggt gttgaaaata gtttaacaga
    51841 cttttgactt cttttatatg atataataaa gtatagtatt tatgaaaagg acatatagag
    51901 actgtaaaaa tatacttttg aaaatctttt tagtctgggg tgttattgta gatagaatgc
    51961 agaccttgtc agtcctattt acagtgtcaa aatagtgcgt tttgagattc tatctacaag
    52021 cctaatcgtg actaagattg tcttctttgt aaggtagaaa taaaggagtt tctggttctg
    52081 gattgtaaaa aatgagttgt tttaattgat aaggagtaga atatggaaat taatgtgagt
    52141 aaattaagaa cagatttgcc tcaagtcggc gtgcaaccat ataggcaagt acacgcacac
    52201 tcaactggga atccgcattc aaccgtacag aatgaagcgg attatcactg gcggaaagac
    52261 ccagaattag gttttttctc gcacattgtt gggaacggtt gcatcatgca ggtaggacct
    52321 gttgataatg gtgcctggga cgttgggggc ggttggaatg ctgagaccta tgcagcggtt
    52381 gaactgattg aaagccattc aaccaaagaa gagttcatga cggactaccg cctttatatc
    52441 gaactcttac gcaatctagc agatgaagca ggtttgccga aaacgcttga tacagggagt
    52501 ttagctggaa ttaaaacgca cgagtattgc acgaataacc aaccaaacaa ccactcagac
    52561 catgtggatc cataccctta cttggcaaaa tggggcatta gccgtgagca gtttaagcat
    52621 gatattgaga acggcttgac gattgaaaca ggctggcaga agaatgacac tggctactgg
    52681 tacgtacact cagacggctc ttatccaaaa gacaagtttg agaaaatcaa tggcacttgg
    52741 tactactttg acagttcagg ctatatgctt gcagaccgct ggaggaagca cacagacggc
    52801 aactggtact ggttcgacaa ctcaggcgaa atggctacag gctggaagaa aatcgctgat
    52861 aagtggtact atttcaacg
//
LOCUS       DAVHBD010000010        49341 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000010 DAVHBD010000000
VERSION     DAVHBD010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.010"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..1605)
                     /locus_tag="VVK04_000595"
     CDS             complement(<1..1605)
                     /locus_tag="VVK04_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3989293.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLF
                     APIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYLNRVN
                     DIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPEQRIALVGQ
                     SGSGKSTLSKILSGLYKIDTGKILFDG"
     gene            complement(1598..2146)
                     /locus_tag="VVK04_000596"
     CDS             complement(1598..2146)
                     /locus_tag="VVK04_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989294.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIKNVLTNVEKIRELNLCHGSVGT
                     ISCLDAILKDEENLLIKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVLLLELRGHDD"
     gene            complement(2227..2289)
                     /locus_tag="VVK04_000597"
     CDS             complement(2227..2289)
                     /locus_tag="VVK04_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEU3989295.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            2369..3223
                     /locus_tag="VVK04_000598"
     CDS             2369..3223
                     /locus_tag="VVK04_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU3989296.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     FNKLVNKK"
     gene            complement(3268..5133)
                     /locus_tag="VVK04_000599"
     CDS             complement(3268..5133)
                     /locus_tag="VVK04_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU3989297.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSYEEMVEMYNVNFTNNDKLYEYRNDRQEKHQQNIHAHHLIQSFSPEDNLTPEEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKVTGAKIIEKRYSYRDYKKYRESSHKFELKQRLYFLLQQSKSFDDFLEKAKQLH
                     VQIDFSQKHSRFLMTDRTMIKPIRGRQLSKRDLYDEDFFKTYFAKQEIESRLKFLLKS
                     VYSLEELHVKAKELNLTIELKQKNVMFTLEEDGKKISLSHKKISDKKLYDVQFFNRYF
                     EDREVRDIQALENLQEDFQTFREEQHKEKVSAEEIEEAFKKYKEKRDAIHEFEIELTD
                     NQIEKLVDDGVYIQVSFGIKQSGLIFIPNYQLDIFEEDNHKKYKVYIRETSSYFVYNK
                     ENMDNNCFIKGRTLIRQLSNDSQKLPYRRPTLKSLKEKISEINLMIELSNTNKQYQEI
                     KDELVLEIAEIDMQLEETQEKIATLNKMAEVLINLKSEDHETRKLAKYDFDQMNMTES
                     IMLDRLNTDILKLQQELGNEINKYEEIARRLDLFVKIINTNKFTVLKFHENALLE"
     gene            complement(5120..5485)
                     /locus_tag="VVK04_000600"
     CDS             complement(5120..5485)
                     /locus_tag="VVK04_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU3989298.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            complement(5495..5854)
                     /locus_tag="VVK04_000601"
     CDS             complement(5495..5854)
                     /locus_tag="VVK04_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989299.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            complement(6673..7125)
                     /locus_tag="VVK04_000602"
     CDS             complement(6673..7125)
                     /locus_tag="VVK04_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989300.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            complement(7053..7829)
                     /locus_tag="VVK04_000603"
                     /pseudo
     CDS             complement(7053..7829)
                     /locus_tag="VVK04_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7857..8618)
                     /locus_tag="VVK04_000604"
     CDS             complement(7857..8618)
                     /locus_tag="VVK04_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU3989301.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(8618..9094)
                     /locus_tag="VVK04_000605"
     CDS             complement(8618..9094)
                     /locus_tag="VVK04_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3989302.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(9539..9820)
                     /locus_tag="VVK04_000606"
     CDS             complement(9539..9820)
                     /locus_tag="VVK04_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989303.1"
                     /translation="MWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(9866..10183)
                     /locus_tag="VVK04_000607"
     CDS             complement(9866..10183)
                     /locus_tag="VVK04_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989304.1"
                     /translation="MNCRGHETRQRIVRDFEVQPKVHIKLLANQQKHSDAGATIEDEY
                     YVFIAESKIDGKKEVIQCCMGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGS
                     GNL"
     gene            complement(10269..12008)
                     /locus_tag="VVK04_000608"
     CDS             complement(10269..12008)
                     /locus_tag="VVK04_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEU3989305.1"
                     /translation="MELSAIYHGPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIASQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEINSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELD
                     NQLVISPDGFMIF"
     gene            complement(12171..13055)
                     /locus_tag="VVK04_000609"
     CDS             complement(12171..13055)
                     /locus_tag="VVK04_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU3989306.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKVL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(13167..14021)
                     /locus_tag="VVK04_000610"
     CDS             complement(13167..14021)
                     /locus_tag="VVK04_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU3989307.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMCISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(14079..14837)
                     /locus_tag="VVK04_000611"
     CDS             complement(14079..14837)
                     /locus_tag="VVK04_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU3989308.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     ISEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKSYFEKNEIFKIQQDVIF"
     gene            complement(14899..15087)
                     /locus_tag="VVK04_000612"
     CDS             complement(14899..15087)
                     /locus_tag="VVK04_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU3989309.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(15409..15975)
                     /locus_tag="VVK04_000613"
     CDS             complement(15409..15975)
                     /locus_tag="VVK04_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989310.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSRFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(16243..17922)
                     /locus_tag="VVK04_000614"
     CDS             complement(16243..17922)
                     /locus_tag="VVK04_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU3989311.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLHIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENISIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(18014..18175)
                     /locus_tag="VVK04_000615"
     CDS             complement(18014..18175)
                     /locus_tag="VVK04_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989312.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(18859..19173)
                     /locus_tag="VVK04_000616"
     CDS             complement(18859..19173)
                     /locus_tag="VVK04_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989313.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(19139..19528)
                     /locus_tag="VVK04_000617"
     CDS             complement(19139..19528)
                     /locus_tag="VVK04_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU3989314.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(19916..20710)
                     /locus_tag="VVK04_000618"
     CDS             complement(19916..20710)
                     /locus_tag="VVK04_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989315.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(20710..21717)
                     /locus_tag="VVK04_000619"
     CDS             complement(20710..21717)
                     /locus_tag="VVK04_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU3989316.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(21717..22724)
                     /locus_tag="VVK04_000620"
     CDS             complement(21717..22724)
                     /locus_tag="VVK04_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU3989317.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(22714..23739)
                     /locus_tag="VVK04_000621"
     CDS             complement(22714..23739)
                     /locus_tag="VVK04_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU3989318.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(24132..24349)
                     /locus_tag="VVK04_000622"
                     /pseudo
     CDS             complement(24132..24349)
                     /locus_tag="VVK04_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24640..24873)
                     /locus_tag="VVK04_000623"
     CDS             complement(24640..24873)
                     /locus_tag="VVK04_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEU3989319.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(25087..26718)
                     /gene="rlmD"
                     /locus_tag="VVK04_000624"
     CDS             complement(25087..26718)
                     /gene="rlmD"
                     /locus_tag="VVK04_000624"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU3989320.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(26792..27766)
                     /locus_tag="VVK04_000625"
     CDS             complement(26792..27766)
                     /locus_tag="VVK04_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU3989321.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(27840..28454)
                     /gene="pmp23"
                     /locus_tag="VVK04_000626"
     CDS             complement(27840..28454)
                     /gene="pmp23"
                     /locus_tag="VVK04_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU3989322.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(28454..29428)
                     /locus_tag="VVK04_000627"
     CDS             complement(28454..29428)
                     /locus_tag="VVK04_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU3989323.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(29436..30692)
                     /locus_tag="VVK04_000628"
     CDS             complement(29436..30692)
                     /locus_tag="VVK04_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU3989324.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYISLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(30754..31185)
                     /locus_tag="VVK04_000629"
     CDS             complement(30754..31185)
                     /locus_tag="VVK04_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989325.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYACDKMQKRFIRIC"
     gene            complement(31187..31789)
                     /locus_tag="VVK04_000630"
     CDS             complement(31187..31789)
                     /locus_tag="VVK04_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU3989326.1"
                     /translation="MMDRIRQELENGGAVILPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(31773..32612)
                     /gene="prmC"
                     /locus_tag="VVK04_000631"
     CDS             complement(31773..32612)
                     /gene="prmC"
                     /locus_tag="VVK04_000631"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU3989327.1"
                     /translation="MKLAQLFSNFEEELIRQGEEEESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPAWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDATDYLKDSGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(32612..33691)
                     /gene="prfA"
                     /locus_tag="VVK04_000632"
     CDS             complement(32612..33691)
                     /gene="prfA"
                     /locus_tag="VVK04_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU3989328.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(33701..34180)
                     /locus_tag="VVK04_000633"
     CDS             complement(33701..34180)
                     /locus_tag="VVK04_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989329.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(34170..34769)
                     /locus_tag="VVK04_000634"
     CDS             complement(34170..34769)
                     /locus_tag="VVK04_000634"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU3989330.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            34892..35074
                     /locus_tag="VVK04_000635"
     CDS             34892..35074
                     /locus_tag="VVK04_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU3989331.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            35211..36584
                     /gene="mnmE"
                     /locus_tag="VVK04_000636"
     CDS             35211..36584
                     /gene="mnmE"
                     /locus_tag="VVK04_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU3989332.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDATPDELITQLF
                     SQFCLGK"
     gene            complement(36631..37566)
                     /gene="dapA"
                     /locus_tag="VVK04_000637"
     CDS             complement(36631..37566)
                     /gene="dapA"
                     /locus_tag="VVK04_000637"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU3989333.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLDHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKIVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFIAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(37622..38698)
                     /locus_tag="VVK04_000638"
     CDS             complement(37622..38698)
                     /locus_tag="VVK04_000638"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU3989334.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGVIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(39040..39112)
                     /locus_tag="VVK04_000639"
     tRNA            complement(39040..39112)
                     /locus_tag="VVK04_000639"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39077..39079),aa:Thr,seq:ggt)
     gene            complement(39212..39721)
                     /locus_tag="VVK04_000640"
     CDS             complement(39212..39721)
                     /locus_tag="VVK04_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU3989335.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(39719..39815)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            39844..40275
                     /locus_tag="VVK04_000641"
     CDS             39844..40275
                     /locus_tag="VVK04_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU3989336.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            40357..40734
                     /gene="mscL"
                     /locus_tag="VVK04_000642"
     CDS             40357..40734
                     /gene="mscL"
                     /locus_tag="VVK04_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU3989337.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(40776..41870)
                     /gene="hemH"
                     /locus_tag="VVK04_000643"
     CDS             complement(40776..41870)
                     /gene="hemH"
                     /locus_tag="VVK04_000643"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU3989338.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSKQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRINENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            42025..43248
                     /gene="pepT"
                     /locus_tag="VVK04_000644"
     CDS             42025..43248
                     /gene="pepT"
                     /locus_tag="VVK04_000644"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU3989339.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(43284..43913)
                     /locus_tag="VVK04_000645"
     CDS             complement(43284..43913)
                     /locus_tag="VVK04_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989340.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            43878..44099
                     /locus_tag="VVK04_000646"
     CDS             43878..44099
                     /locus_tag="VVK04_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989341.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(44370..45381)
                     /locus_tag="VVK04_000647"
                     /pseudo
     CDS             complement(44370..45381)
                     /locus_tag="VVK04_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(45595..48714)
                     /gene="phtE"
                     /locus_tag="VVK04_000648"
     CDS             complement(45595..48714)
                     /gene="phtE"
                     /locus_tag="VVK04_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU3989342.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGISHEKHEEDGYGFDANRII
                     AEDESGFIMSHGNHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTAGYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(48924..>49341)
                     /locus_tag="VVK04_000649"
     CDS             complement(48924..>49341)
                     /locus_tag="VVK04_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU3989343.1"
                     /translation="KNKADQDSKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT        14699 a         9793 c         7887 g        16962 t
ORIGIN      
        1 accatcaaat aaaatttttc ctgtatcaat cttatataat cctgatagta tttttgataa
       61 cgtacttttt cctgaccccg attgaccgac tagtgcaatt ctctgttctg gctcaatagt
      121 caaatttaaa ttttctatta caggagctga gtctttggaa taagagaaag ataggtcctt
      181 aatatctatt ctaccttcta aagaacactt tttaagacca ttttcaacat tctcttcatt
      241 ttcaagccag atatcattta ctctatttaa gtatcctgct gccaaaatat actgcgtata
      301 agcattaaat attgagattt ctgaactaaa taaaattgat gccatggttt gaaatgcgac
      361 aacctcaccc aataaaattt ttccatttaa aacattatca agtccaaaaa tcaatataat
      421 tataggagcg aacaattgaa atacattagt agctgaattg tataaaatat gcacaatact
      481 tcgtttttta tactttgtca atacgttttt taaatactta gaccagtttt catatatttc
      541 atcttctaat cccgatattt ttattgaaga aatagtattt aatgcttctg tttctactga
      601 gtaaatcaat gattgttctt gtaattctct attaaccgta tcatacatta tttttctagt
      661 actaaacaga aacaaaaaat tgattaaact caatataaga gctataattg ataatgtttt
      721 tgaactaaga aacatatata ttacaacact tagaatagtc ccgatatcta ctactccccc
      781 aacaacttgg ttagtaaata gctccctaaa accactaaga ctagaaattc tgtataaaat
      841 atctcctttt gccctgagtt caaaaaaact atatggtagt ttaagcaaat gcttaaatgt
      901 aaaactttca atatctctac taaaaaatat attagaaaat agaattccca tactcctagc
      961 caagatagaa ataagataca aacaaagtag agaaaataaa attaaaaacg aggtttgaaa
     1021 agaaaatgta ttccctaatg cagaattaat aaactttgaa gtcattactg gtacggaaag
     1081 tattattaag taacttatta ttgaaaatag taacgtcaaa atcaatcgac cttttacctt
     1141 tgaaaaacta gagaatactc ttatccatgg agaaggaaac tgcgacttca aagattgata
     1201 attttcgtta ggaaatgata gcagtactat attactaaaa tgttttgaaa actccttaaa
     1261 ctcataattt atatatcctt tagaaggatc cattatatag accttattct tttttacttt
     1321 gtaaataact acataatgtt gattatccca gaatgctatt aatggtaacg gaagttcact
     1381 aattttattt acatctttaa cttgatatga gccagtatca aaatttcgtt tattcaataa
     1441 ctgtttcaag tcacctatac tataaccatc tctccctttt tctatatcac gtcttaaatc
     1501 tagtaatgtc tctttgcttt tatagaaatg tagtatggac aagcagcaac ataaaccaca
     1561 ttctatttga gacatttgct caatattagg tacttttcta gtcatcatgt cctcttaact
     1621 ccagtaataa aacattaagt aatctatcat cttgttttcg agatatttca tagacaactc
     1681 cagatactcc tagcataaaa gaaaatgtat tcatagtatt caaatccgta cttaattctg
     1741 gtttgatgac ctgagaaacg acattatcaa aataaaaatc tatagattct tttattaata
     1801 ggttttcttc atctttcaat attgcatcaa gacaactgat agtacctaca gaaccgtgac
     1861 ataaattcaa ttctcttatt ttttctacat tagttaatac atttttaatt attgataaat
     1921 cattattccc aatattagtt ttatcgaaaa tttcttttct agctaataaa atgcccggag
     1981 ctccataaca ccaaaaatta ggaaaggaat cattatgatt tcttcttatg tctttccaat
     2041 tttttaatat attattgaaa catttatctt ctttatatag taattcctct atacatttta
     2101 atatatctgt actaggatta atttcataat aatatgataa tgacattgct actccagaat
     2161 aaccgtgtgc taaacctgtt actgttatat tatctaattg tgaaatacaa taattaatac
     2221 acttttttaa atgatgataa tatccatcac caaaaccaaa atcggtaaaa attttgaaat
     2281 tttcttcata cttggacttc ctttccgttt ttatttattg tacaataaat aaaaacggat
     2341 ttaatttttg ttgggaaaat gggaaattat gaaatcaaaa cttggcatca cacttagaaa
     2401 agttcgtaaa ggaaaacaaa ttagtctatg ctctgtagca gatgaacatc tttcaaaatc
     2461 acaaatatct cgttttgaac gtggggagtc agagatatct tgtattcgac taatcaatat
     2521 tttagacaaa ttacatatta ctttggatga gttccttgtt ttacacaatg acgactatac
     2581 cagttccgaa tcatttgcta atctagtaca gtacattcgt aagcaatatt catcacaaag
     2641 tatcaataat atagcatgtc tactttctga tacttctgat tacactctaa attcttttga
     2701 gaaaacaatg gtaaaatcta ttttacacac aatggattcg aacatcattc catcagatga
     2761 agagcttctt catctgacag actatctttt caaagttgaa aaatggggct attatgaaat
     2821 cattttatta ggtaactgtg tacgcacaat taactacaac tcctacttct tattaactaa
     2881 agagatgtta aataactata tttactcatc tctgaataaa actaataagc agattgtctc
     2941 tcagcttgct attaattgct tcattctaag cattgataag gaagaatttt ctaattgctc
     3001 ctatttaatt agtaagataa agacattgtt ggacaatgaa ctaaactttt atgaacaaac
     3061 agtttttctc tatgcaactg gttactttga atttaaacgt tgccaatcaa ccagtggaat
     3121 tgaaaaaatg aaacaagcca tacaagtctt cgatatttta ggagaagata agttaaaatt
     3181 acactatact gaccatttta ataaactagt aaataaaaaa taaatgaaat tattctctat
     3241 cttttaacta attagtcgta aataatatta ttctagtaag gcattctcgt gaaattttag
     3301 aactgtaaat ttattggtat taataatttt cacaaacaaa tccaatcttc tagctatctc
     3361 ctcatattta ttaatttcat taccaagttc ctgttgtaat tttaaaatat ccgtattgag
     3421 tcgatctaac attattgatt ccgtcatgtt catttggtca aaatcatact tagctaattt
     3481 tctagtctca tgatcttcac tcttcaaatt gataaggact tccgccatct tgtttaaggt
     3541 ggcgattttt tcttgggttt cttctagctg catatcaatc tctgcaattt ctaatacaag
     3601 ctcatctttg atttcttggt attgtttgtt cgtgttagat agttcaatca taagattaat
     3661 ttcagaaatc ttctctttaa gactttttaa agttggtcgt ctatagggga gtttttggct
     3721 atcgttgctc aattgtctga ttaaggtcct acccttgatg aaacaattat tatccatgtt
     3781 ttctttatta tagacaaagt aagaagacgt ttctcgaatg tagactttat attttttatg
     3841 attgtcttcc tcaaaaatat ctagctggta gttaggaata aagatgagtc cactctgttt
     3901 gataccaaac gaaacctgta tatagacacc atcatcaacc aacttctcta tctgattatc
     3961 cgtaagttca atctcaaact catggatagc atctcgtttt tccttgtatt tcttgaaggc
     4021 ttcctcgatt tcttcagcgg agactttctc cttatgctgc tcctctcgaa aagtctgaaa
     4081 atcttcctga agattttcta atgcttgaat atctctaact tctctatctt caaaataacg
     4141 attaaaaaat tgaacatcgt acaatttctt atcgctaatt tttttatgac tcaggcttat
     4201 ctttttgcca tcttcttcta gggtaaacat cacatttttc tgttttaact cgatggttag
     4261 attcaactct ttagccttta catgcaattc ttctaatgaa taaacagact ttagtaaaaa
     4321 ttttaaacga ctttcaatct cttgtttggc aaaatatgtt ttaaaaaagt cttcatcata
     4381 taaatctcgt ttgctgagtt ggcgtcctcg aattggtttt atcatcgttc tatctgtcat
     4441 caaaaaacgg ctatgctttt gactaaaatc aatctgaaca tgcaactgct ttgctttctc
     4501 taaaaaatca tcaaacgatt tagattgctg tagcaaaaaa taaagacgtt gtttcaattc
     4561 aaacttatga ctagattccc tatatttttt ataatctcga taggaataac gtttctcaat
     4621 aatttttgca ccagtcactt tagaaatacg gtctgaaatc atacgaaggt ttcgttccaa
     4681 ggcataattc catatcaact ttttatctga attacagtca atggcgttga ttaagatgtg
     4741 attatgaata tgatctttgt ctgtatgagt cgctacgatg aaacgaaaac ggcctcctgt
     4801 taattccata atggtctcat aaccaatgcg attaatttct tcaggtgtca gattatcttc
     4861 aggagaaaat gattgaatga ggtgatgggc atgaatattt tgttggtgtt tttcttgtcg
     4921 gtcatttctg tattcgtaca acttgtcatt attggtaaag ttgacattgt acatttctac
     4981 catttcttca tagctaggaa agtctaagta attgctcata ccaaaatcag atactaattt
     5041 caaattgtcc gttttatcag gattgaggat atacttaatt aaacgcctac gatatttttt
     5101 tccgtgtgtc gcaaaatgct tagtgactac catgaaactc cttcaatctt ttcacttcca
     5161 cttgaaattc tttgtccact tccttgatca actctccgac tcctttactc aattcttgta
     5221 actgttcctg agaaatcaga cggctttgat tgatagcacg cgcaatttga ttaatgttat
     5281 ttccgatccg tctcaattca aaaactaact ggtcataagt atccgtgtta atcgtgacaa
     5341 atgacatatt gggattaagc aaaacttttc tggcatagac tgaaaaattt tgacaattgc
     5401 tcttagcaat ccgttcattc aattggtgta attctgaatc tgttagaaat acttttttga
     5461 gattggtacg ataacgataa accatagtag cctcctatct catgtatttt tcacgaaacc
     5521 cacgactgag tgactgtact tgattgactt ccgcaatcaa ttcttgaacg caggtcaata
     5581 agattgacac gtgttcttga gtcacttggt gattctctct tgcgataatc aaaaccaaat
     5641 gcacatctcg actgatctgt tcaaactttt gagactgcca aagggaaaac cattctttgg
     5701 cagctaactg tttgtcatca gtcatcaaaa ttttatccct gacgaatggt gaaaagtgac
     5761 gataattatc aacctccatc attttttcaa tctgttttag ctcatctgcg gttagattta
     5821 cctcttttcg aatgtcacgg tactgttcag acatctcttt tcctcacttt catcctttct
     5881 cgggtaaacc ccgaccccgt gtgtcatacg ggaaatttct taaagtcctt gttcggtctt
     5941 tgcgagctca ggcattgtgg tcacaatacc caaaaaatca tatcgccagc taaccaaaac
     6001 cttccagttt tgacagctaa ccataagata acttggtggc tacgccccca aactcccagg
     6061 taaaattctt agttggattt ttaaaagttg agaaaagtat agcagaagaa agttggggaa
     6121 gttatcacaa atcaagtagg gactaatctc taacaccact gcatgtaccg tcctatattt
     6181 atgatcagct cccatcgttt acatttttag gtcactgtct tttcatacca ggaattagaa
     6241 ttgacaaatt taattagaga ggtattcatt taattgttca cttcttcgct ccatttccat
     6301 tacagaaatt tcttcaatac tatgtgttca gctgactccc atgattcgtt gtactacgtc
     6361 ctaaacgctc acggaataag ccgtacatct ttcctagttt actctcgtaa tttacgtata
     6421 taggttacga cacctatttg gattttagag ttcctcatcc gctatatatg gcttcaagtc
     6481 acgattctgt ttgtagaacc ttgatttcgc taattccttc ctatcccccc tacctcacga
     6541 tattcaggct taggagtcgc tattggtttc atctgcagca aatatccaca gaggacttgg
     6601 acctcagatg tacactatgc ctgtcgaaca aagaaaaaag taggctaaat ttctaaccta
     6661 ctttttctga ctctactctg ataaagccgt ctcatatata gacattttat gcttgaagga
     6721 atcttttcct ccctctaatt gattgatgat atgatttttt atatattttt cactaacata
     6781 tccctgtgat tcaatccatc cgttaactcc atctgactcc ataataacaa cttgatctgt
     6841 catagaattt gttacaattg tagcattatg tgttgctaaa ataatttgac gttgagcttt
     6901 cacatctcta aactgctgaa ctaaatgcct gtaaatataa cgattgtcta gattgtcttc
     6961 aggctgatca ataatcaatg gtctgaagtc tttagaatag tcactatatg ctaataaaaa
     7021 atcaagcatg gctacaactt tttgtcccaa acttaataca ccaacttctt tatagagaat
     7081 atcaagttgt tgcgaagatt ctttcgagtt aatattaaac tccaaaaatc gtgtattttc
     7141 tttagaaaaa atttttcgtt tatatgcacc tgataagtga gaaccttttt tcaaaatgtc
     7201 ataactattg aaatgagcaa tatagttaac tattttttga ttattgaaat ccttcattat
     7261 agtcagtgaa tgttgataac ttccatcttt ctcacttata atattttcac ttaaccattg
     7321 attaacccat gattcttgtt cataatcata tatacataca atatgcaatt tatctgctgc
     7381 actaatttct actccatgta aaatatgagg atgtatatca taaatcggat aatttttcat
     7441 tatgattgag actgccattt gtaacttttt aatacctttg gtagtattat gatcagttac
     7501 tacaactatt tctattccat tttttatgat tgcctctgct aacataagaa aactaatata
     7561 ttcttttgaa ctagaaaaaa caaccttatc aaaattacta aaaaaattgt cttatcaact
     7621 tttattttct tattttcaaa aaatatatca tatagttcat cttcagtaat ttttctatat
     7681 ttcgttgcag tccaattaga aaatagcttg taatcataag aaacaggtgt atgcaaatga
     7741 attaaagtct tgtgaaagct accgaatttc tctttggaat ttgttagttc ttgataaaca
     7801 gactttatct tgttattaaa ccctctcatt tctactctcc taaaaatatc aattgtttat
     7861 ttttcaagta attcattaag tctcttttcc cccacctgca acatctcctt ctctacctga
     7921 ctccactccc caaacagtaa ctcttgaaga acatctgctg ctgaagttgt attttctttt
     7981 gaatcatata cacaacttct atctcgttgg taaatttgaa ttctttcaaa gatagccagt
     8041 tcttccaatt gtcgtgtatt atcaactaga tgatttacaa tgaaatcatg atgttctttt
     8101 ggagttgcgc gtgcttgatt tggattgata atgtacagtt cttcataacg gataagagta
     8161 cttagatacg acaattcagg ctttgtcgca attaaggcca attgtacttc atatccctta
     8221 tttttcaaga gttgtgccgt tttctttgga acatcaattg ttcgtaaagt tccctcgatc
     8281 aaaagattgt atcccaaact actcaatttt gttactaaag actctaccat ttttcctgca
     8341 aaatctttgg tgtattcaac gctatctttg ccatattctt gctgcagttc taaatagtgt
     8401 ggatgctgag aacgaaaact atcgccatct atgataacaa tatttccttg aaattctttc
     8461 tgtttaatac gatgaattgt agtcttaccg gcaccacttt gccctccaag caaaatcgct
     8521 ataggttgtt tactggactt ttttcctctt gtcagtgaac gaagattcct tgctaaagca
     8581 tgtttgaatt cactatcagt ataatcttgg atttccatta agctaccatc cgcttttcag
     8641 atatctctaa catacgttca attccatcca aatagccact atatctctct atttcatcaa
     8701 aagtttctac taaatagata ttcgtatgaa tcaagtcaga tagatcatca ctcattaaaa
     8761 tccaaggatt agattcatca tcaatgctaa ttccctgact atcttgataa cgatagagtc
     8821 gagataatag attagcacct ctttctttca caatttcaat tttcaaagtc aattcataat
     8881 cttcaacagg attgagcatt ttatcttctc ctacaatatc gacataagat acattaaact
     8941 tctgacaaat gatgtcaatt aattctgtag agactgaact agttccattt tcataacgac
     9001 tcaagctatt tcgagaaatt cctataattc gtgcaaattc gggttgtgtt aagtcatgtg
     9061 ttttacgtaa ggattttatg ttctttccaa tcatagcaaa ctcctttatt tttataaatc
     9121 cattatagca taaaaaagca taacgcacca aaaatggtgc gttatttctt gtgtttctat
     9181 cctaaacttt acttctataa aagtcaccta aagagccata aatatttatt cttgtattaa
     9241 ttttttcgat gcgcaaacga tatctacaaa tacatctata acgattcacc ttttaggatt
     9301 tttattgtca aaattgcctt tatctacaaa gacaaaatgc ttataaaata gtttgaaatc
     9361 aaggattatc gcctttttcg ttgtagcaac actccacatg tgattattag gctattagca
     9421 aagcgtatcc aatacctcaa taaagtgttg tttttactga tattttaact atattgtata
     9481 gtctactatt taaatctcaa ttaggatatt ttatagaata cccaaaattc aacaataact
     9541 aaaagtaaga ttccattgta tttccttgtt ggtctttcat atcacgaatt ttatttttca
     9601 gaatattaaa gttacaaatt tcatctctaa tatcgttatc cgctctgtag ccattaatca
     9661 tctcagtcag agttttccct ttactaccat tctttatagt agtatttact ctttttatac
     9721 tgctttcaaa aggctcatat gttttatact taattacttc gtctttaaaa ttaaataaag
     9781 gtgtatccgg cttagcattc cataaaataa tcaaccacat tatagcatta taaagctgct
     9841 ttgcagtttc attccacttt tcaggttata aatttccact ccctgtattg tcatattctt
     9901 gtctattatt tacatgagaa tcacctacaa gcggattaaa aagaggtagc cctttgtgat
     9961 taattagttc taaaaaatcc cttgccgcac ccatgcaaca ctgaataact tccttcttgc
    10021 catcaatttt actctcagcg ataaatacat aatattcatc ttcaatagtt gctcctgcat
    10081 cactatgttt ttgttgattt gctaacagct taatatgtac tttaggctga acttcaaaat
    10141 ctctaacaat tctttgtctt gtttcatgtc ctctacaatt catttaagtt ctcctttaca
    10201 agtttagtaa ctagccttat tatactatat aaggtatgaa atgtaccata atcttcatca
    10261 actagttttt agaaaatcat aaatccatct ggagagatga caagctgatt atccaattct
    10321 tggcaattgc ttgctagtgc tactgcttct ttctctaaaa gataatcttc tgttgattgg
    10381 ttgaatattg ctttgaggat ccgtccttcg tatttccatt ccagagctac tagatcagag
    10441 ttgatttctt gaaggctata cttgccatgc gaaatgatta ctgacgcgta tttccgaatc
    10501 ttaatcagcc tcttcataaa gttcagcata tcattgtcac ttgatacacg ttcccaaggc
    10561 atacaacgac gacaatctgg atctggtcct ccagtcaagg ctagctcggt tccgtaataa
    10621 atgcacggtg ttcctttttg taaaaagaga aaggctaagg ctgatttaac cagttgaaca
    10681 tcttcattgg ccgtccacag gattcgctct gtatcatgtg aatccaagag attaaacatg
    10741 acctctgaaa tctgctgctt gtaatacata gactctccat tgatttcatc gatgaactgg
    10801 tctgtcttct taattcctcg taagaaatag tccttgatac tatcagataa aggataattc
    10861 atgacggcat ggaactcatc tccatttagc caaggctgag atgtatgcca gacttctcct
    10921 aggatataaa gatcaggatt tttagctaaa actgccttac gaaaatcctt ccagaactga
    10981 tggtcaatct cattagccac atccaaacgc caagcatcga tattaaactc ttcaatccaa
    11041 taagtcgcaa cctttaaaag ataattcttg acctctggat tggctgtatt tagcttaggc
    11101 atatagtcct cgaaaccaaa aacatgatag ggtaagtctc tcttattaac tagcttttca
    11161 gttgtcactg ggaattgttg aatatggaac caatccttat aagcagactg ttcaccattt
    11221 ttgacgacat ttttccattg aagagattgc gaagcaatat gattaaatac cgcatccagc
    11281 atgactttca tgccacgatg atgcgcttga tccaccagtt cccgaaaggt ctccttgtct
    11341 ccaaaatgac ggtcaatttc aaagtaatct gtcgtattgt acttgtgatt gcttgtagat
    11401 tcaaagatgg gacaaagata tagtccagta atacccaagt cttgcaagta atccatatga
    11461 tcaataatcc cctgtaaatc accaccaaag aaatcatcgc tcttaggtgt gacagatgaa
    11521 tcccagtcta aagtcccttc tgggtttaat agagcattgc cattggcaaa tctttcagga
    11581 aatatctgat accataccgt atttgaaacc cagtcaggaa ccttgcaggc atcaatctca
    11641 tgaagataag gcaacttaaa tccattccca attgcatgaa gattttctag agaattttcc
    11701 acacaccctt tatcgccata caaaatattt tgaccttctg tatctctgag ctcaaagaga
    11761 tactggatac gtgcaaagtc aactgacact tcaacctgcc aatggtcaaa taaggtacca
    11821 gaagttatct tgaccatttc ttttgtatcc tgataaaact cctccataaa gataaaaggg
    11881 tccccatagt gcaagttgat gctttcaatg tcccctttct tagttcgaat tcgaatatgg
    11941 agtttcttat ccttataaag ataggcatac tccgactcag gcccatggta aatagcactc
    12001 aattccatca atttgtctcc taaagtattc attcaaattt tacgcaaacg ttttcaaact
    12061 caataaatcc agtatactat ttttgtaaac tatttgcaag gaatgtccgt tgttaaagga
    12121 actatctttt aaagtataca aaaagcctta aaaaaggctt tctctatata ctaatcctct
    12181 ttcggttttg aaaatacttc tactcgctga gctaggactt tgatttctac aggtaggtta
    12241 tctgatttat ctccgtcaac atctgactcc aattcactat ctgaagagat tttaatatta
    12301 cgcgctttga tatactcgat attatcattt gcgacaacat ccccttttaa taaatcagga
    12361 atgacggata atttggagaa tatagaggca tctttcagaa tcaaaatgtt ggcatagccg
    12421 tccttgtttt cttcaaagat tttcttatca gcgaagtaat ttgtcaaaag gaccaaaaca
    12481 tggctagctt caccaacata atttccattt tctgtctcaa ccttaatgtt aaagacctga
    12541 tctgtcatga cagacttcat ggtatttaca gcataggtta aaataccgaa ttttgttttg
    12601 tcctctattt caacattgtg aatcgcctca ggcagagaac cgatactaaa gatataacca
    12661 aaatagttgt catttgcttt accgatatca atcttattgg ttaaatcaaa atctagttcg
    12721 tcaattgcgc catcgatgtc ttgattgatt tccaaaagtt ttgtaatgag gttacccgta
    12781 ccgcctggga taatccctaa cttaggaatg tagtctctct catcaatacc tgaaatgact
    12841 tcattgacag ttccatctcc accaaacaca accactgcat catactgctc acgagaagct
    12901 tcttcagcaa aatgtgttgc atccagcact ttttcggtaa ttttggtttc aacatattca
    12961 aagtattctt ttgctttatt ctccagcttt tctttgtaat ccaaagcctt ctcgccacca
    13021 gaagtagggt tgataattac cattgctttt ttcattgatt ttatccttaa ttttaaacag
    13081 aaatgtttac atttcgtcgc atgcaagtaa atgtaatcct attatacaat gaaaatacag
    13141 aaaagagaaa tctgacgtac tggagattaa tacgctttta ttctattttc ccatcgccta
    13201 actacatcct ttaagggttc atccaagtaa gaataggcct tatccttgat ccaatcagga
    13261 ataccgtaag ctgcctctgc tatgctacaa gtgattgctg cgagagtatc actgtcgcca
    13321 ccaagtgaga tggcatttct tatcgcatct tcgaagtctc tactttcaag aaaggcgata
    13381 atggcttgag ggacagtttc ctgacatgtt tcgttaaaac gatagttagg acggatttca
    13441 tctaaagttt gagatagatt gtaatcgtat tctttttcta tataatcctt aattcgtctt
    13501 ttacactctg taggattgtc gttaattgat tgctcgtact ctctacaata accaccaaag
    13561 taaaaacgac atagaaagat agcatcagct gtagccatag cgcctttgac accttctgga
    13621 tgattatgag ttacctctgc agaaagactc gtaagtcctc tagatgatgg ccacatacca
    13681 gttttcgcat aaaaaccaca gtccatgatc caagcacatg gagaaataca catagctgat
    13741 ccattcccaa agctattata aggctcacgg ttatcgctgt ttagccatgc attaaaccga
    13801 gcaccgtaat cagcattcgg atacattctg ccatatttct tcatcgcgtc aatgaaatcg
    13861 tctttttgtc caccattcat aattgcttct gcaacagcac aggtcataac cgtgtcatct
    13921 gtaaaaaagc agtccttccg aaataaagga aagtcctttg ttttgatatt gttccattcg
    13981 taaacagaac cgacaatatc tccaataatt gctccaagca tcagattcct ccttgttcat
    14041 tttgatgctt tttatattgg ttatctacca tatttatttt agaaaataac atcctgttgg
    14101 attttaaaaa tttcattttt ttcaaaatag gattttacca tttctttcca cctagctcta
    14161 tgaaaattga ttgattttaa aggagatagg ccataatttc ccaatgcata accatcattt
    14221 acttcaacaa caagtgttct gccatcgcga gtaacaccga tatctagtcc ataagctatt
    14281 ggcgcatctt tccaacatga tatcgcttca tcaattacac ttgcatcaaa ttgtgcatga
    14341 taatcacctg tatagggtcg aacatctaat acgcgaccat ctaacacaaa acaacgccat
    14401 tcagctatga attctacaac ctcactaatc catataggat agtcgaaagg tagaccaata
    14461 cctattaaat catgggttcc attaacaact cttccagtaa agacttttga accagcttta
    14521 ggcttaataa attttcccca attatcaggt atattcacaa tctctcctaa aataccagca
    14581 taaatctttc gaccataaaa ctctttaagc tcaataggat agtcataaac cggaacgttt
    14641 aagcccatca tttttagtaa tgctctagtc tccattatat aatctacaac tatatcttca
    14701 cttattaact cttttatttc agaaaaagat tgatataaaa taacttcttc tccttgtaag
    14761 taggcaccta cttgagcatt gtatttatta attgaaacct cacttggtaa tttactttgt
    14821 ctaatataaa caaccatttc atcactccta tatcactagt gttacaccaa tttgtaaaaa
    14881 ataatagcaa ttttgctctt atttttttga gtaaatagcc cccataatat catcgaaata
    14941 atcaacggta tttaggagta attcaataac ctgggacttt gttagtcgca ttccccttct
    15001 atctctagca tcttctacta aattttcaag tttctctaga tttttatcat ccaagctaat
    15061 cattattcta tttttatcgg ttgccatttt catcacctca agttaattct atcacaggtg
    15121 taacacttgt gtcaactggc ttttataata cattagttta aaagtggaga ggatttttaa
    15181 cacagtaact ttaaatcttt ggtattaaaa aattttcaca atatttatag aaataaaatc
    15241 tgtctcaaat cagttatcaa atctagtata aattatgagc ggctactcta atactttccc
    15301 tctaaacaag aaaaagactt acactcaagg gttttcttcc cccccttcgt tataacgttt
    15361 tgactctttt actagcaaag gtatatactc acaaggaact ttggttgact attgaatctc
    15421 tccaacttct tctttaacat atccttctac atcttcaatc tctacaaaca ttgggtctaa
    15481 gtgacacaag aaatgccaaa cttcgatccc tttttttctg taaagaatcg cttcaccgtc
    15541 ttcacttccg aaaaagcttc tgtcgatttc atatccgcgg ctttctaaga agtcttttgc
    15601 tttacgatag ttcgtttctc ttgtttcgac ataggcttta acttcatggt tgttaacgac
    15661 atatgcatca atttttgaat atccttcgat cactctatca tttttgaggg ataaatttga
    15721 aatctctttc caaataatgt ttacattttc cccaggatcg aacataaatc tagataaagg
    15781 aacaatattt ccgttaaaaa taatttccat ataatccggt atgtttttag gattaaaata
    15841 ctccacttca aaaccatctt ctgtttccag agtgtatccc gggatttgag ctacaaaggc
    15901 tttcccatct tctatggaat caaatgctac taaatcttta gaataatcat tttggtacaa
    15961 ttccaatata accatcgata atctctccat tttcattatc aggctaatgt aaataagcac
    16021 gtcacctgac caattcaggc tctctgtatc atctcatcat atttcctact tactttacga
    16081 gtcctatacc cagaacacac cttatcgacc ttcggtctca cctcgtcgca ttggctgaac
    16141 atctactttt actttgctga tgcttcaact cgtacaagca gtgataccgc ctcagcgtga
    16201 tgcgtcagtg ggactcaaaa ggttcgggga accttttgag gattaactac gtttctctaa
    16261 taaacttaca cattcaactt gttcatcatt gtccaaacct atgttgagat tttcttctat
    16321 aattggtagc ttaaaagtaa tggattttag ccattgtccg ttagattgtt tttcttcata
    16381 aacttgaatt tcagaaatca aagctgaaat taactgccta cgctctacat cattcatgac
    16441 tttatagagc ttatcaaaat agatcagaac cttatatatg ttatctcctg taagcttttc
    16501 agcttcaata gtctgtttct ttgctttcgc atcaattagt gatgattcta attcatctat
    16561 tttgtcatac atacgatata gtctatcatc taaatcctgt ttccttctct tataatgctt
    16621 atcttcaaca tctaaattat ctatttcctc aattagctta aactttgtag aatgactctt
    16681 tctcaattcc ttttggtaat tatctatttc tttttctatt tcagaggtat ccaccttcat
    16741 gttgattttt tcttgcatca tagaagcaaa tttcggatta cttactatct tgacaatcac
    16801 ctctgcaaca gcatcatcta acaattcttc tctaatttgc ttactgaatg tacacttatg
    16861 acctcttatc atctgcctat gtttacaacc atagtaataa aaatctttat actttgtgcc
    16921 atctttcttt ttcttgatac acttgttccc aaacattccc actccacata tcgggcattt
    16981 tacaattcca gaaagcaagt gtgtgcgtgt atcttttcct ttattcacat gctcatattt
    17041 ctttgcttga gattttagct taacctgagc agcttgccaa acttcatcgg aaactatagc
    17101 ttcatgtatc ccttcagata ttagatattc atcttgttca acctgcttat attcatttct
    17161 tgtaccatga actttttcta aagttcttct tccaaatgct attttcccat tatatacagg
    17221 attctttaat atctttctta taagacctgc atcaaacaaa ggattcttac cattctgtct
    17281 tgggattttt ctaattccat gattctctaa gtatttagat atcccattgg ctcctatcgt
    17341 agtatttaca tactggtcga aaatcgttct tattgcaact gcctcttcct catttataaa
    17401 cagcttgccg tcttcaagtt tatatccata cggagcaaag ccaccattcc attttccttc
    17461 ccttgctttt tgaatgcgac cttccattgt ttgaatactg atgttttctc tttctatttc
    17521 agccacagct gataaaacag aaatcattag tttcccagca tctttagatg aatcaatgcc
    17581 atcttcaacg cagataagat taactccata atcctgcatt atatgaagtg tagaaagaac
    17641 atcagcggca tttcttgcaa atcttgataa cttaaacaca agaacaaaag atactccatc
    17701 ttttccagat tttatatctt ccatcattcg attgaactgt attctacctt caatagactt
    17761 gccagacttc ccggcatctt catactctcc aacaatttca taatcgttgt aaatagcaaa
    17821 agctttcatt cgtgattttt gtgcctctaa cgaatacccc tctatctgta ttgacgtaga
    17881 tactcgtgta tagaggtata cttttatttt ttcttttgac atagtattaa tctcaatata
    17941 atttttctat atcatatata atttttttaa tttaagtttg gactatcatt tcaagtatat
    18001 tataacactt ttattagtcc gtctcaattt gtgtttttgc catgtcaaaa ctatttttca
    18061 tctcttgatt ttttgctggc gttggatcgg gtagattatc taaatctaaa gcaccagcat
    18121 attttgcaat cagatttgct attaaatcag ccaatccatt ccagtcattg tccaatatat
    18181 acctcctcta aagttttata tctaataatt atttgtttaa ttaagttttt tgacattgac
    18241 aagtgctttg gattagcaac ataggaatct cacctccgcc tctattccgg atgagccggc
    18301 ttcaacctta gaagtatcat tatcctcatt ttcttcatag cggatagggt atccctccct
    18361 atattcaaac tcttacttat cgctcacttt ctttttgctt agcagaactt tttttgccga
    18421 attattcagc cgaaagatct tgacggatag gttattacgc tccaaaaata attaacgtct
    18481 tgtcttggtc tattcaattg ttaaggttca aaatttatcg agagttatta atctttttaa
    18541 aatttgacca tcagaaaata tttatcttga tgtaacaaaa ttctataaat taccctctta
    18601 tacttaacag tgaaaagaag tctttcttgg taaccaattt tgaaatagaa tttgcttata
    18661 taaaaaggtc aaattcccac tgcataagta gcagtgaaaa ttagaccctc ttggtaactg
    18721 tcatctaaaa gtcttctagc atttctttaa ttttctaatc gcctttaaag tgtcatattt
    18781 atattttttt atctctggca tactttgata cctttttaga cttaaagtct ttaatagtgc
    18841 ctttccacct ctttttatct ataaagattc tcctacatca taattcattt ttttatttaa
    18901 acctttctgt cttagtttgt ctttatcttc ttcataccat tttaagattg tcacatagtg
    18961 gttttgatag gtcttaccac tgctttccat gtatctggat agtttattta tcattatatc
    19021 tgtgtgtgag tttaattttt cttttagatt tttatattct tctttgctta accttacatt
    19081 tttgaattct ccataaaaaa tgggggtgga ctttttatct atctctccct ctctctcttt
    19141 atctatctct atatctttcc atgtaattcc aatctggagt acctctactg tctatcggta
    19201 atttaatttt gatatctggc aatactgtgc tagatatttg atctttatat tcagtatttt
    19261 ttaaagcttg cctaataatt gaagttaaat agaatgctac ttctttattc aattctttat
    19321 tttttaattt taaacaatga attttcatat ctaggcttgc tttatattta tgataaaaga
    19381 ctgctcctaa aaatgaaaca gatataaaat tttcaaaaac tctataattt ttatcatcta
    19441 tatcttcgta gtaacctaag ataccattgt caatatttgt agcactaatt ctaggagttt
    19501 ttccatcgag taaatatctt tttggaatag atgagcctgt tggtacttaa ctcgatttcc
    19561 cctttttttc ggtaataaat atttcttttt attttgttgt ctgatatttt tcctacctgt
    19621 cctttgtagg atgagtattt tctagatttt cttgaataac tttttacttg aagttttagc
    19681 ttttgaacta gtcgttgtac tttctttttg tttattatca gtcctgatct ttttaatatt
    19741 gctgttattc tctatatcct atttttcatt catgatattc ttttactaat tttatcttaa
    19801 attctgtgct gtatttgcca ttaaaaaact gacctccttt agttagtttt ttggcctaac
    19861 ttttgagggt cagttcaaaa tttgcgactt ttaaatgaat tccaatattc aattattaag
    19921 agttaacatg gtgcttgcca ataggaatca ttagaggcga attggaaata gggtcacgta
    19981 taatttttgc ttcaagatta aagatatctt taactagttt atcatttagt atatcttcag
    20041 gctttccctc tgcaacaagt ttaccttctt taattgcaaa taggtaatca gcgtatcttg
    20101 ctgttagatt tatatcgtgc aaaatcatgc aaatggttgt cttatatttt tggtttagat
    20161 cagtcaagag gtctaatagt tctatttgat atgagatatc caagtaagta gttggctcat
    20221 ctaaaagtag gatacttgta tcttgggcta gggctagagc tatccatact ctttgccttt
    20281 gacccccaga aagttcttca actaggttat ttgctagatc ttcaacattg gccttaacca
    20341 ttgatctgtt tattatttca aggtcatctt ttccaagact cttaaaaggc tttctgtagg
    20401 ggaaacgacc acggcttaca agatcagcta ctgttattga ttcagggatt attggagatt
    20461 gaggtaatat agctatgtgt tttgctaaat ctttttcttt ataagaatta attgatttat
    20521 tatcaagcaa tacttctccc tctaatggct ttataagtcg agacaaggtt ttaatgagtg
    20581 ttgatttccc acaaccattt gacccaataa taactgatat tttttcttca ggtattttta
    20641 tatttatatt ttccaagatt attttttcat cataaccgca ggtaagatta tttgaccaca
    20701 gacctttcat tatatattcc tcctgttcat ttttattagt aagtatatta agtatggtga
    20761 acctaacaag ccagttacaa cacctactgg atatctagct ggtaaaatat tttgagagaa
    20821 tatgtctgat aacaaaacta gtaaaattcc aaccaatcca gctaatattg ggcttctttt
    20881 cttgccaata tttaaggcta tgggaccagc taaaaaagat atacaagcta ttggtcctgt
    20941 aattgaagta gaaaaagcag ttaaagatac agcgcaaaaa attaaaacaa gccttgaaag
    21001 ctcgggattt gctccaagtc cgattgctat ttcttcacca agttcaataa tttctagtct
    21061 tttattaaaa aataaaacta atatagtagc aataatactt actattagaa caagaggtat
    21121 gtcatctaac tttgtaaaag ataaagagcc actgagccat ctcataactt cttgtaattc
    21181 atatcttgct actttcaaca ataaaaatga ggtgcctgct cttgtgacag cttgaaaacc
    21241 aatacctaat attatcagtc ttgctgctga aaaaccatct tttttagcta gtaaaaataa
    21301 tattaaagat gatgttagtc cacaagttat tgaaataatt ccagtagtta aactatttgt
    21361 ttttaatacc aatatgcaaa agaccgctgc aatagatgaa gaacttgtga caccgattat
    21421 atcaggactt gcaagaggat ttcttaacat agtttgaaag ataaatcctg ccaatccaaa
    21481 agaccagcca gctataattc ctgctaataa ttttggtaat ctaatttcca taatcgaaaa
    21541 actagctcca ggaacagttt cactatttaa gactttaatc aaagttgaaa aagaataact
    21601 ttcatctccg ataagtaaaa tgaaaaatga tagactgatt attattaata aaaatagtga
    21661 ggaaaatagt gttattctat tttttctttt ttgaatacct ataattaaat tttgcattag
    21721 ttattaaccc ctctattttt catagttaca taaataagta ctggaccccc gattattgca
    21781 gtaattatcc ctacttcaat ttcacctggt ttacctaaca tacggccgat tatatcacat
    21841 ataagcaaga gctctgcacc tataaaagat gaagaaatgg tcattgtgcg tatatctttg
    21901 cttataaata agccacaaaa gtgaggaact ataagaccta cgaagccaat aggtccacca
    21961 attgcagtaa tacttgaaca taaaagcaca cttgcaatta ttgcaagtga tcttatccta
    22021 ttaacattaa ctccaagacc aacagccatt tcatcaccca tagctaaagc gtttaaatct
    22081 gatgaaataa atatagctat caagtgacct aaaattataa aaggtagtag tgtagatata
    22141 gaagataatg tagctgctcc aaggctacct atttgccaaa atctaaattt gtctaagacg
    22201 ttattattcg gtaaaattaa aaaacttaca aaactgctta aagccatact aacacaagtt
    22261 cctgataagg caagttttat aggggtaagg cctgcttttc cgcttacagc aatcgcgtat
    22321 acaaaaattg cacttactaa gccaccaatg attgcaaaac ttatatggct tatgcttgat
    22381 gaaattccta aaaaagaaag accaattact acactaagac ttgctcctgt gtttataccg
    22441 agtatacctg gatcagctat tgggtttcta gtaactgatt gcatcaatac accgcttatg
    22501 gcaagactag aacctgctaa aattgcaaaa atagttctag gtattctttt atatataatt
    22561 gatttaataa aatcatcatt tgtattgccc attccaaaag ctgctaaaaa atctctgata
    22621 ttaatttctt ttgttccaag ctttaatgac aaaaatattg taataagaag acctaggcag
    22681 attacaaaaa ttatgcctag gtttatttgt tttttatttc gcatttttgc atgcatttcc
    22741 taaaagattt aggtattctt caatagtata gtttattgaa agtggtgttg gagtgcatga
    22801 ggctgctaac ggtgtattat ctggaattac agcaacggca ccatttttaa ttgcatttat
    22861 tttacctaaa agaggatctt tttgtaaagc ttcaagagtt ttatcatcac cataagttat
    22921 gattacatca gcatcattta tcttatttgc ttcttctgca gaaatttcct ttgcaaaact
    22981 atcttcactc tcaaattctt ttaatgattc agggaaaact agacctaaat ctgttaaata
    23041 atttgctctt ggatctttgc tagtataaat ccagaatttt gatgtatctg cagcattaat
    23101 catagtaaat aatacttttt ttcctttgat ttttcctttg atttctggat gtttttctaa
    23161 ttctttggat atacgagctt cagtattttt gattaactca tcaccttctt tttccatacc
    23221 taaggctttt gaatcaattt taatcatatc tctccataaa gtttgccaag gtttagattt
    23281 gtatgctgct acaggagcaa tttttgatag agtgtcataa tcttctttag ttataccaga
    23341 ataacctgct aagataacat ctggtttaga atttgatatt gcttcaaagt taagtccatc
    23401 caaatcgtca aataggttag ctttaccatt tagttctttg attttttctt ctgtccatgg
    23461 taaaactcct ttatcagcac ttacaccgta atttgctttt gaaaatccaa caggaactat
    23521 tcctaaagct aatgctacat catgatttcc ccaagcaata gttgcaactc tttcaggttt
    23581 tttatctaat atagtttgac cgaaagcatg atctaaaact attttatcag gcgcatgctc
    23641 tttagaagta ttttcttcat ttttaacaga attagaagaa caagcgctaa aaactataca
    23701 catagctaaa atagctatta gaaaaaattt gtttttcata aaaactcctt aaacatattt
    23761 caagtctatt gtatcgataa taattatcat tgtcaataga tacagttaca aatttaataa
    23821 tataattttt tcaaaaaagg atctagtttt tatttttagt taaattatgt ctatattttt
    23881 cattaactca tcaataaaaa tttgtttgct aatatctctt tcttctgatt ttgtttcaag
    23941 gattattgct acatcattca tatttttagg taaataccaa ccatctggct tatctgaata
    24001 tcccttgaag cctaattgat taaaagtagt tatttgacca gtaccttgat tgatgttttc
    24061 ttcaacttca ttaaagccta tacttctctt gcataatccc taacttgatc ttctgtcctt
    24121 aaagtcattt tctattcctc gtcactaaaa ttatcttcaa aactaataat atcattagga
    24181 gtgcaagata aagccttaca tattctttct aaattcttaa atgtaattgg tttatccttt
    24241 cccatttgtg ccataacatt tgttgtaagt cctgccatag ttattacatc tgttttcttt
    24301 agtctttttt tgctaactgt atccataatg gtttatagtt aagtgccata atatccctct
    24361 ttttttcttc attaaattta tttaattata gcataaatat tgatttcatt caatcttaca
    24421 ttgatttagt gatttgtttt agagaatttg ttgtgttatt ccgtccttat tttgccataa
    24481 attgttttaa gtgggacctc ttatccttac catttttacc tcctaatttt gagtataaaa
    24541 aagacgatag agtttttaat ttctatcgtc tgagatttac atattaaatt ttcatcacaa
    24601 aataagactc tttaaagaat ctttaaattc attggtatgc taattacaat atccattatt
    24661 aaaatggata ctataagcag cacaccaact atttattttt tgagttttaa actttggtag
    24721 aagtcttgaa ctccttatat ttacataact atttgcctct ataactatta tgacacgaaa
    24781 ccaacaagca agttcaagca cctccatatc tttattcaaa tgaggactaa gatattcaca
    24841 aactttatca taaacctctt tatctttttt cataaaaggg gcatacaact tagcaaattt
    24901 atcctaaaat tttttgttgc ctttatcaat catttcaacg ctcctttaaa tataaaaatg
    24961 atcctatcaa tctttatatt gagcctattt tctaattgat accttgcaag aaaggaataa
    25021 tagctgttcc tataccaagt aggaatgtaa taaatgcaga aagtcatata ctgtcattct
    25081 tttctattaa atcattttga agtgtctcaa agcatccatg atggcttctt ctttttcagg
    25141 tgtacactgt ggaataattt gtttatcctt tttagacttg ttgtaatgtt ctcgtaattc
    25201 tattccacat ttctttttta tctgtgcaat atataatgtc gaaactttta attcaaattt
    25261 attccaaaca tattctttga tttgagcata tgttgctttg ctctccgcac ttgtcaaatc
    25321 catctcatcc agctcaattt caacacttat gtgcttatcg acatcgagtt tggacaaaag
    25381 tgctaccgtc tcgacgtgat gcgtttgagg aaatagatcc accggctgga ctttcttcaa
    25441 ttcatatccc aactcttggt atagtttaat atcacgcgcc atggttgcga cattgcagga
    25501 gatataggcg atgcgatcgg ctcctgtttg ggcgcttgct ttgataaagc tttctgtcaa
    25561 gcccttgcgt ggaggatcaa ccaagataac ggttggttga ataccttcct tgagccattt
    25621 cttcatggca ttttcagccg tgtcacagac atagtgggca ttagtaatct tgttcaaaga
    25681 agcattcttc tggctattct ctactgcttc tggaatcagt tcaacaccgt agacttcttt
    25741 gacatgcttg gcgactgata aaccaatggt tccaatacca gaataggcat caataatcac
    25801 atcatctttt tttaactctg caaagtcaat ggctgtttga tagagtttct ccgccatttc
    25861 agtattgact tggtaaaagg ctgggccagc gatttggaag tcatttccca acatctggtc
    25921 cgtaatatag tcttgaccat aaagagtgcg ccactcctta ccaaaaatcg cattggtatt
    25981 ctggtcgttg atattttgca tgacagacac aatctctggg aactgcttga taacttgttc
    26041 aatcaattgg tcaacacgaa aaacttttgg acgagttgtc accaaaacga ccatgatttg
    26101 tcctgaatag tgaccacgac gcaccacaag attccgaatc aatccagact gttccttttc
    26161 gtcataaggt tttaaatcaa aacgacggag caggtctcga agagctacta cgacttggtc
    26221 aatgacagga tcctggataa agaaatcttc aaggggcatg aggtcgtgcg aattcttacg
    26281 gaaaaatcct gtttccaaga caccattcac tcgacgaacg ggcacctgcg ccttattgcg
    26341 atacttgact ggatgttcca taccaagcgt ttcagcaact tctacatctg caattccagc
    26401 aatcttgtag agactgtcct tgacttgctt ggttttaaac ttgagctgtt ctggataaga
    26461 aaggtgtcct aaatccgcga ttcctgaacg caggtaagcc aaatctagat cttgattacg
    26521 gtgtggtgac tggacaaggt atttttcaac ttttccaaag ccaatctttt tattgacctt
    26581 gaggacacgc atgagaattt tttcactcgg taaagcattc tctacaaaaa agaccaaacc
    26641 atctaccttg gcaactcctg ccccttcatg ggtcaaatca acaatttcaa cttctacaat
    26701 atcatttttc tttaacattc ttttctcttt ctattggccg acaaaaaaga cggcaacgtt
    26761 acggttacca tccattatac catgaaattt cttaagaacc aaaactcttg aagaagttga
    26821 caagggcttg ccagagggag cttaagaagt taccaccgtc ctctagcgcc ttatccgcat
    26881 caaagttaag gttgatattt ttaaaactgt cgccagcttg tgatacgatg ctttgtttaa
    26941 ggtcatttag ggttttagtg aaatctgcat tgctgaggat atcactcttt gagagattca
    27001 aggcaaaatt gatgatgata ttgatctggt ttcctgttat gacctgatca agtttgtaat
    27061 tttttaaggt atcttcaaca atcttgcgga catcttcttc tgtcagattt cccttgcttt
    27121 ctttagcttt ggcgagtcct gacttgatat cagctagggc aacgtttaat ttattagcat
    27181 catagcctga tttgtccttg ttttcagcat tgatatctga caaagccttt agctcttctt
    27241 gagccaaatc tttattggct tgcggcacct tggctccatt agcttctagc gaatagtaga
    27301 tcccagccaa agcactctca cctgtaactg gaataggggc tgctacagtg attttggcat
    27361 gttccatacc cagcgttact gctgcgtttc ggtacatatc ctgagtcacc ttagtgatat
    27421 tttctggtgt ttcaatcttg acctcaagtg gcgatttgtc acctagcttt tgaatcttgg
    27481 ctgatgaata caactgtaag ctagagtcat tggccacatt catgatttta gaataaacat
    27541 caggtgtcat ggtcttgagt tctttggtat ctgttgaggc attgtagccc agttttttaa
    27601 gagtttgatt tttttggtct tcagataggg aggaacctag gacatattca ggttggacat
    27661 aggtttcatc gataactttt tgaacatctg ttgctgcatg gacgctattc atagctgtta
    27721 ctgcccacaa gaccgcagca ctggtcagaa agagtttctt tctcataggg aatttcctcc
    27781 tttacttttc tagagtaata tatctatctt aaagaaaact tataacaaaa acacctggtc
    27841 tagccagatg ttgaaaagag agtgaaacat ttgatgatgt aaaggttaag tcgtacctgt
    27901 ctagaataat aatagtttcc tccatttaca tagagttcag caccgtgaaa aatggaaatg
    27961 gggtgaatat aactataagt ctttccagtc ctattaccaa gcaagggggc aacagtctca
    28021 cgagagtact gtttggctag agccaaggta ttttccttgc cattttgggc gataaaatcg
    28081 atataggcag gtccaaaatt ataggcttga acagctgtcc agatatctac ccccttcttc
    28141 tgcgccagat agagattgcc tgtcagagtt tgaatgcctt gccgaatgct agaggcatta
    28201 tcattgatgg tgttggttga accacttgca gactcactag actgcataac atcgccttct
    28261 tttccttttg tttcagtata aatcatagca agcacaagct cttcgtttgc tggggtgtct
    28321 ttttcactca agatttctcg caccatgggt tgataggtca tgacttgttt gacatcttga
    28381 tgaacgcggt aagctttata gccagcaaaa aggaagactg ctagtacaag cactcttcga
    28441 attcgtttaa acattattta ctttggatat cctcgatatt tttgattaag atagagtagg
    28501 ttccattttc gttttggata aactcaacag actcggcgtc ttgatagacg ttattgggaa
    28561 cgatgagctc aattccattt gataaggaga gtttttggtt ttcaaatttc tttaattggc
    28621 gactggcatc aatttcatca aattgaacag gttctggtac ggcttctttg acttggtcaa
    28681 taaagctcaa acgagccgtc agattgttgt caaaaaggtc attagccaat ttctcaggtg
    28741 acaattcatt gctttcttct aggttgttga aaatcgctga tttgaccttg gattgaaatt
    28801 gaaaatcatc tgtgttaaaa gattcagcaa ttctctgggc tgttttttcc agttccttga
    28861 tagatttttt aggagaaatc ttaggagcga cagcaagaag attatctgaa aaatagttca
    28921 aaaaagtccc gttgtacttg attcgttttt caatcaggtg atacttgcga ctctgaagat
    28981 tgaccaccaa ggcctcgtca gcacccgttc caaatccagg caggttattc tgagtcagct
    29041 tgattggatt atcaacttct cctccgaggt gggtcaaggt ctcccgcagg gcaattcgca
    29101 agaaagcgaa atgttctaca ccttctttag aaaattgaac aaaaatcaag tcattggtct
    29161 tgagattttc agaaatgcta aactcctctt tccagagatt agccagcgtt actgatgtct
    29221 ccaacaaatc gtctgtaata tgattgaaga agggattttc ttcttcgaaa atcccagtct
    29281 tggcttcatc tgaatacaca tgttcaattt ttttacgtag gtattcttcg atttttggag
    29341 taatattgag aaacttatct gctaagaaca gctcggtatc atccggactg aactggtgaa
    29401 taatggcttt cttaatataa atgtccataa aagttttatt cctcgtataa tgggaaggca
    29461 tctgtcaatt ctttgactgc acttctcact tcttctaata cagcctcatt ttctgaattc
    29521 ttaagggttt taatgatgag ttcagccact ttgcgacttt cttcttcacc aaatccacgt
    29581 gcagtaatag ctgctgctcc gatacgaatc ccacttgtct tgaatggtga caagctttcg
    29641 taagggattg aatttttatt tagggtaata ttgacttcat ccagcaagtt ttgagcaact
    29701 tttccgtttt ctacaacctt agtcacatca acaaggaaga gatggttttc agttccacct
    29761 gaaataatac ggaaatcagg gtcttgcaag aagacatctg ccatagcctt gctgttctta
    29821 attacattgg cagcatattc cttgaaggct ggatccaaaa cttctttgaa ggaaactgcc
    29881 ttagccgcca caacatgctc taaaggaccg ccctgaatac ctgggaaaat agctgaattg
    29941 atttttttag caagttcttc gtcattggtc aaaatcaaac caccacgagg tccacgaagg
    30001 gttttgtggg tcgttgttgt agtgatatga gcgtatggca ctgggcttgg gtgaagacca
    30061 gctgcaacca agccagcgat gtgggccata tcaaccataa gcttcgcacc gacagcatct
    30121 gcgatttcac ggaattttga aaagtcaata atttgagaat aggctgaagc accagctaca
    30181 atcagttttg gttttacttc ttgggcttgt ttcaagatag catcaaagtc taagagttcc
    30241 gtttcaggat caacactata agaaacaaag ttgtaggttt gaccagagaa gctaacagga
    30301 gccccatgag tcaaatgacc acctgatgcc aaatccattc ccataaccgt atcacctggc
    30361 tcaatcaagg atatgtaagc cgcacagtta gcttggcttc ctgaatgtgg ttggacattg
    30421 gcaaatttag caccgaaaat ttcttttgcg cgttcaatag caagagtctc tacaacgtct
    30481 actacatcag ttccaccata ataacggcgt cctgggtaac cctcggcata tttatttgtc
    30541 aagatagacc cttgagctgc cataacagcc ttggaaacta cgttttccga agcaattaac
    30601 tcgatattat tttgttggcg ttcttcttct ttggcaatag cattccagag atcagcatca
    30661 tatgctttaa aatcatcttt gtcaaaaatc ataggtcttc tcctttattg tgtgactagt
    30721 ccattagttt gattttacaa taagaaaatc aaactaacag atgcgaataa accgtttctg
    30781 cattttatca caagcatagc caactttttc ataaaatgca tgagcaccca gacgatgatt
    30841 ggcagaattt aagcggataa acccataacc acatcttttt gcttcttctt ccaacccttg
    30901 tagtaaactt ttaccaatac cttgaccttg cgcttgaggt gaaactgcta aagctaagat
    30961 attaaatcct gctttagaat agagtgattc gtaaacttca gcgtggacat atccaagtaa
    31021 gacatgatta gctgcatcct catagccaag taggaaatga tgggaatcct gagacagtct
    31081 agctagttgg ctagccgttt cctctggact aaaagtataa cccaaagcct cttggttgat
    31141 gtcacatatc gctttcacat ctgtttcttg caaatctctt agcatttcaa gcctcctcaa
    31201 aagaaatctc tggcaaccga gcaagaatat cttctcgttt aattgcgcct tggcgtaaga
    31261 ttttcacctt gtctccagac aaatccacaa tagttgaatc ctgtccagtt agaaaagcat
    31321 cgtcttccag acccagaacc tcttggtcaa aatccttcag aatttgttca aaggttacac
    31381 cacttgcctg acctgagata ttggcagacg gcccaatcaa gggacctgtc tctcgaatta
    31441 aatccagtgt gatagggtga ctgggcatcc gaaatccaat agttgcaagg tcagaattta
    31501 cccaataggg aactcggtca ttggcttcga gaataatggt caagggacct ggcaaaaagg
    31561 tctctacaag tttttgtaga taagctggct gattctttga aaagtgcaag atgtcctcga
    31621 aagaggcgat attgagattg agtgccttat ctctaggacg acgtttgagt tggtaaacat
    31681 ggtcaactgc tttttcatct aaggccttgg aaaaaagacc ataaaccgtc tctgtaggca
    31741 gaatgacagc tccaccattt tccaactctt gtctaatcct gtccatcatc aaccacgacc
    31801 atcctatctt gaccaaattg gtccttgagt gttcgaactc ttttttcagg aagatgtttc
    31861 ctaaaaagtt cgggaacact ttgaccttgc ttgtatccaa tttcaaggta aatcttacca
    31921 ctatctttga gatagtctgt tgcatcttcc gcaattctac agtaaatagc taggccatcc
    31981 tcgtctgcaa agagagctag atgaggctcc gaatgcaaaa cattcaagcc tacctctgac
    32041 tcatcttcac gagagatata gggtggattg gatacaatta tatcatattt ttcagaaatt
    32101 tctgcaaaac aatcagattt tttaaaaaat atattaagat tttgatcgct agcattctct
    32161 gatgcaagct ctaaggcctc ttgagaaaca tctgctgctg tcactgacca agctggtcta
    32221 ttttttgcta gagcgagagc aatagctcca ctacctgttc caatatccag aactgagaga
    32281 ttcgtctcaa gattttcagt tagaataagc tccactaact cctctgtttc tggacgagga
    32341 atcaaaaccc gttcatccac ctttaaatgc attccataaa aatctgcctg tccaatgatg
    32401 tactgagctg gcttgtgagc tgctagttgc tggtaaatat cttctacaaa ttgtttttct
    32461 tcctctgttg tcacctcctg ctggagggca aaaataaagt ctgtaaaaga tagatttttc
    32521 agactacgat agacaaaaga gaggctttcc tcttcctctc cttgtcttat caactcttct
    32581 tcaaaatttg aaaataattg agctaatttc attatttgtt taattcttct agtttttgtg
    32641 tttggtcata aagcaccaag gcatccacaa cttcgtccaa tttaccagac aaaatcgtat
    32701 ctagtttttg gagggtcaag ccgatacggt ggtctgtgac acggttttgt gggaagttat
    32761 aagttcggat ccgttctgaa cggtcaccag taccgattgt cgacttacgc tcagcgtctt
    32821 gttcatcctg agcaatctga gcaaagtggt cagcgacgcg tgcacggata atcttcatag
    32881 ccttctcgcg gttcttctgc tgggtacgtt cttcctgcat ctcaaccttg atattggttg
    32941 gcaagtgaac gatacgaacg gcagtcgcaa ccttattgac gttctgtcca ccagcaccag
    33001 aggcgtgata gatgtcgaca cgaaggtctt ttggatcaat gtcgtattca acctcttcaa
    33061 cttctggcat aacaagaact gtcgctgtcg aagtatgaac acggccttgg ctttctgtca
    33121 caggaacacg ttgcacacgg tgggcacctg attcatactt aagcttagag tatacagact
    33181 gacctgaaac catagcaacc acttctttaa aaccaccgac accattcata gaggcttcca
    33241 tgacttcaaa gcgccaacct tgggcttccg catacttttg gtacatagtt agcaaatctc
    33301 cagcgaaaag tgccgcttcg tctccaccag ctgctccacg gatttcaagg atgatattct
    33361 tgtcatcgtt tggatccttt ggaaggagca aaattttcag tttttcttca tattcttctt
    33421 tttcagcctt ggcatctttg agttcttgct tggccatttc ttccaagtcc gcatctccgc
    33481 ctgattcctt aatcatctct tcggcatcga cgatattttg aaggacttgt ttatactcac
    33541 ggtaggctat tacggtgtca cgattggaag cttcttcttt tgaaagctcc ataaaacgct
    33601 tggtgtctga aacgacatca gggtcactca gcaattctcc tagttcttca taacggtctt
    33661 ctacagcttg tagttgatca tagatgttca ttttttctcc ttatttctca attgttaaat
    33721 catagattgc tactacttca ttctcggata tttccccagt ttctttaaat ccataactga
    33781 gataacaaaa tcttgcctgt tcattttctg gttcataaga caaccaaagt ttattgctta
    33841 aacctgctgg cgctgttcga acatagtcta gtactttatc cataattggt ttaaaatatc
    33901 cttgattttg aaaattctta tcaatcataa aacgaaatag taaataattt ccactactaa
    33961 ttccgatctt tttatcataa gctatcatca caaaacctat aattacatca ttatcataaa
    34021 ctgccaatgg agctacaaaa tctccatttt tagtgtagac gtatgcttca gctaaactaa
    34081 ttgcgttggt tgcaatgaat tgtttttgat attccttgac atccaaattt aaaacatcaa
    34141 aataattttc cattgtaaca tctcttagtt caattgtcat agttttgctc cttgttagag
    34201 gttatcattg gcgcaaaata atgtttacgg caaaccgaga tataggtttc attaccacca
    34261 atctggatct gttctccatc gtaaacgggc agtccatcct gtgttcgcaa caccatggtc
    34321 gcctttttct tgcaatactg acagatggtc ttgatttcgt caatcttgtc cgctaaaagc
    34381 aagagatatt tggaaccttc gaacaattca ttgcgaaagt catttttcaa gccaaaagcc
    34441 atgacgggta tgtctaactc gtccacaaca cgagctaggt cgtaaacatg gtggcgttta
    34501 agaaactggg cttcatcgac caaaacacag taaggttttt ctggtaggtc tcggatatag
    34561 ccaaagatat ccgttgtttc ctcaatcgca agggcagggc gtttcatgcc aattcgactc
    34621 gacacatagc caacaccgtc acgcgtatcc agagccgagg tcataatgac aacacctttt
    34681 ccttgctcct cgtagttata ggccactttg agaatctcaa tcgttttacc agagttcatg
    34741 gtcccataac gatagtacaa ctgtgccatg tttcttgctt cacgtccatt tctaaatttt
    34801 tgctacattc tagtatatca taattttctt aagctttaaa cggcaaaatg tggtaaaatg
    34861 gaagaaatca aaactagtgg aggaagctat tatgccattt gtacgcatcg atttatttga
    34921 aggacgcacg ctcgagcaaa agaaagctct tgctaaggaa gtaacggaag cagttgtccg
    34981 caacactgga gcccctcaat ctgctgtcca tgtcatcatc aacgacatgc cagaaggaac
    35041 ttacttccca caaggggaaa tgcgtactaa ataagctagc ttaagcagaa ttgcttaggc
    35101 tttttcaatc tccaagtagc attcattgaa gaaatatcct aaatttgtta caatttgaaa
    35161 agaaacttgg agaatttcca agaaaagagc tattaattaa aggaaacatt atgattacac
    35221 gtgaatttga taccatcgct gctatctcta ctccactagg tgaaggggct attggtattg
    35281 tccgcctgag cggaacagac agttttgcta ttgcgcaaaa gatttttaaa ggaaaagact
    35341 tgaacaaggt tgccagccac actctcaact acggtcacat tattgatcct ctgactggta
    35401 aagtcatgga cgaggttatg gttggggcta tgaagtctcc aaagaccttc actcgtgagg
    35461 atattatcga gattaacacc cacggtggga ttgcggtgac caatgaaatt ctccagctag
    35521 ctattcgtga aggggctcgg ttggcagaac ctggtgaatt taccaaacgt gcttttttaa
    35581 acggtcgcgt agacttgaca caggcagagg ctgtgatgga tatcatccgt gccaagactg
    35641 acaaggccat gaacattgcg gtcaaacaat tagacggctc cctttctgac ctcattaaca
    35701 atacccgtca agaaatcctc aatacacttg cccaagttga ggtcaatatc gactatcctg
    35761 agtatgacga tgttgaggaa gccactactg ctgttgtccg agagaagaca atggagtttg
    35821 agcaattact aaccaaactc cttaggacag cacgtcgtgg taaaatcctt cgtgaaggaa
    35881 tttcaacggc tatcattgga cgtcccaacg ttgggaaatc aagccttctc aacaacctct
    35941 tgcgtgagga caaggctatc gtaacagata tcgctgggac aacacgagat gtcatcgaag
    36001 agtacgtcaa catcaatggt gtacctctca aattgattga tacagccggt attcgtgaaa
    36061 cagatgacat agtggaacaa atcggtgttg agcgttcgaa aaaagccctc aaggaagccg
    36121 acttggttct actagtgcta aatgccagtg aaccactgac tgcgcaagac agacaacttc
    36181 ttgaaattag ccaagatacc aatcgcatta ttctacttaa taaaaccgac ctgccagaaa
    36241 cgattgaaac ttcgaaacta cctgaagacg ttatccgtat ttcagtcctt aaaaaccaaa
    36301 acatcgacaa gattgaagag cgaatcaaca acctcttctt tgaaaatgct ggcttggtcg
    36361 agcaagatgc tacttacttg tcaaacgccc gtcacatttc cctgattgaa aaagcagttg
    36421 aaagcctaca agccgttaat caaggtcttg agctggggat gccagttgat ttgcttcaag
    36481 ttgacttgac tcgtacttgg gaaatcctcg gagaaatcac tggggatgct actccagatg
    36541 aactcatcac ccaactcttt agccaattct gtttaggaaa ataagaaaaa tccatgatcc
    36601 ttcattcggt catggatttt attgtcttta ttagtaatct ggtcttaaga cacctgttac
    36661 agttgccttg gtcgcttcgt agtcgccatc tacgacaacc ttgataatgc gtttagcatc
    36721 ttcttctggt gctggaacaa gaggtagacg agttggtcca gcttcaaatc ccatgtagtt
    36781 caaaactgcc ttaactggag caggacttgg ataagagaag agagcattaa ccttaggaat
    36841 gaatttacgt tgaatagctg cggctttctt catatcactt tctgcaatgg caataaacat
    36901 ctcgtgcatt tcatccccat ttgtatgaga ggcaacagaa ataaccccat ccgccccaag
    36961 gttcatggca tggaaagcat ctccatcctc accagtatag accaagaact cttctggttt
    37021 gtgctcaatc aagtaagcca tattagccaa gctagtacat tctttgacac cgataatatt
    37081 tggatgatca gccaagcgaa gcatggtttc tggagttaat tcaacaacca cacgccctgg
    37141 aatgttatag ataataattg gtaggtcaga agcatctgca atggctttaa aatgctgata
    37201 cattccttct tgagaaggtt tgttgtagta aggaacaata gcaagaccag cagcaaaacc
    37261 gccgaattcc gctacttctt tgacaaactc gatagagtca cgcgtatcat tagtacctac
    37321 acccgcaatc aaaggaactc gtccattgac aatcttttgt acagccgcaa ataactccaa
    37381 ctcctcatcg tgggtcaaag ttggactctc agcagtggtc cctgcgagaa gaattccatc
    37441 cgtatgatgg tccaataaat gctcaatcaa ggctggaata gcatcaaagt tgatggaacc
    37501 atcctcgtgg aagggagtaa taaaggctgt gatgatttta cactctttta aatcttgata
    37561 agacatgaaa acacctctct atttcaaaga aggagttcat ctgaactcct aaacgatatg
    37621 actattttaa ttcaaatttc aattcagctg ttggacgaac caatccacgt tcatgaagag
    37681 tttcagcaat ctgaactgag ttccaagcag cacctttgag aaggttatct gaaacaaccc
    37741 acatgtgaat tcctttttct gcatccaagt ctttacggat acgaccaaca aaggtatcac
    37801 gtgaaccaac tgcattgata gcttgaggat agatttgatg agctacatca tcttcaagaa
    37861 cagcacctgg gaaggctgcg atagctgctt ttacttcttc gattggagcc acttcttttg
    37921 tttcgatata aacagactca gagtgagctg acaagactgg aatacgcaca catgttgcag
    37981 atactgcaat gctatcatct tccataattt tcttagtttc cttggtcatc ttcatctctt
    38041 cgtacgtgta atcattatca gtgaaaacat caatttgtgg aagagcattg aaggcgatag
    38101 gataatgttt cttgtcacca cctgaaggca agatttccgc atgcaaatca cgtggtttca
    38161 caccatcatt caagacttca cgaagttcac gttgtgtctc aagaattgct cccataccag
    38221 cacctgaaac ggcttgataa gttgaaacaa tgatacggtc caagccccat ttttggcgaa
    38281 ccggctcaag agccaccatc atttggattg ttgaacagtt agggcaggca atgactccgt
    38341 tgtgggcatc aagtgcatga gcattgacct ctggaacaac caaaggaaca tctggatttt
    38401 gacggaaata agatgtatta tctactacta ccacgccagc ttttactgcg tatggtgcat
    38461 acttagctga tgtagaacta cctgctgaaa agagagcaat atcaactcct tcaaaagctg
    38521 tttcagtcgt ttcttcaatt gtaatatctt gatctttaaa tttcaatgac ttacctgctg
    38581 aacgtgcaga agcaaggtaa cggattttat cgattggaag tgttgattct tccaacattt
    38641 ttatcatctg agcaccgaca gcacctgtcg cgccgactac agcaactgta tatcccataa
    38701 ataacctctt tcggaatttt ctaaaaattt ctataataga agtattatac tactttttcc
    38761 atgaattgca aagctttttc atcatttttt ggaaaataaa aatcccagtc gctagactag
    38821 ggactaagag gcatcttcat gtgatgagca ggttcacaca actcatcaag gtccgctcct
    38881 gcgttatgac ctccttatgc tcaatagtag tccgaagact acctatcgac tcatcgcata
    38941 ttctatatta ctagagatac ttgattttgt caataagaaa ttttttcgat cgagtataac
    39001 aaaaaactct catattcaag agtttcccta tacatatcat gctaattgcc gggattgaac
    39061 cggcgacctc atccttacca tggatgcgct ctgccaactg agctaaatca gcttacttaa
    39121 gaagtatact atattcagaa aaacttgtca agtttcctta gaaattttcc ataggaaaaa
    39181 gccaggtaag aactacctag cttatcttct tctatttact taaatcaatt cgacgaccaa
    39241 ttttaccaat aataatcgcc ccaataatca atgaagcaaa ttcaccgatt cctgttgtaa
    39301 accaagtaag gaagaatggt aattctgcta caatatttaa ctctgcagcg atagtaaaca
    39361 tggaaattga aaagaggatt gaaaagaaga aatgatcttt tcgaatcaat ccgttaaaga
    39421 ggtaatcctt gctatatttt gcaaaaagcc aaacacctaa actgaggaat actaaggttg
    39481 aaccaccacc aacaaagaca tctagcagtc cgaagctaaa gaaattagca atcatacaac
    39541 cgatggtaac tccgatgatg tacttaggat tgtaaaaagc cataaagttc atcatttctg
    39601 aaatacgaaa ctgataagca ccatagctga tggcatttag gggcggtgtg acagtcaaaa
    39661 cgacgtagat agcagcgacg attgcaatat ctgcaacatc acgaatagtt aattttttca
    39721 tcttttctcc tttggcggtt atccgcgtgt aatatgcttg gtgaaagaag ctaagcacca
    39781 agggttgatt cattcaacct tactagtata gcacaatagc ctgctttatg ctatacttaa
    39841 agcatgaaaa aacctattca aaaatttttt aacaatgaaa tcttagccta tctctttttt
    39901 ggccttgcga caactctagt ttcgattctc tcacgactag tcatttatca actaagtcat
    39961 caggaactcc ttgctacggc cttggcaaat attatcggta tcttatttgc ctttatcaca
    40021 aatgatacga ttgtatttaa gcaaaaaaag aaaaatagac ttatccgttt agtgaaattt
    40081 tctcttgctc gcctttctac ttttctgtta gacttgtttt taacttttct ctttgtaacc
    40141 caatttcctc acatcatagg gcaattcgta actgaaaaca ttgataagat aaatgctatt
    40201 gaaacaataa ttgcacaaat attcattatt atcatcaatt atatcttgag caaggtctat
    40261 atttttagaa aataatgctc catttatgag ccttttaatt gccttctata atgatttagg
    40321 atacaatgaa acacgaaaca ttgaaaggaa aacagtatgt taaaaaatct aaaatcgttc
    40381 ttgcttcgag gaaatgttat tgaccttgct gtcggtgttg tcattgcctc tgcttttggt
    40441 gctatcgtta cttcacttgt aaacgacatt atcactcctc ttattttaaa tcccgctttg
    40501 aaagctgcta aagttgaacg tatcgctcaa ctttcttggc atggagtcgg ctatggtaac
    40561 ttcttaagtg ctattatcaa ttttatcttt gtgggtaccg ccctcttctt tattatcaag
    40621 ggcattgaaa aagcacagaa actgactggc ataaaggaag aaaaaactgc cgaaaaaaaa
    40681 ccaaccgaat tggaagtcct tcaagaaata aaagctctcc ttgagaaaaa ataatcgatt
    40741 aaaaggatct agcgcaaagc taaatccttt tttctttact ctttgggtaa cttgcctgct
    40801 ttttcaagca tttttttgat aagataaggc atcttaacat tctcccgccc ttttttctca
    40861 atcagttttt tcacaaattc tggcatttgt aaatcttcag attcagccaa aatgtttttc
    40921 gtctcgtctg aaggaactaa ctcatcaaag gtctcttctt ctgggagaaa ttccttaaac
    40981 tcttgatttt cattgattct aattgtattg accaaagcat caatcaaacg agaatctgta
    41041 tttggcattg gtggacgatg gtagtttacc ccaaattcct gacataagtc ataacattcc
    41101 acatcgttgt caaacaagac ctcaatatgc tcactgatga aactaatagg tacaaaaata
    41161 taatggtctg gatgttctgt ctgttctctg agatactcca aaacatctgg tttaatccat
    41221 ggaataccaa tatcactctc actctgccaa gtgttggtat attgttttga actcaagccc
    41281 agtttttcag cgactagctt gctattttcg aaaatttggt ctatataagg atcaccaaag
    41341 tccaaggcaa aaataggcac actatgggct gaaaagatga ctttaaagct gtcttgcttt
    41401 acttcttctt ttaaaatctt agcaatttca tctgcccaat agtttaagag cgcttcttcc
    41461 tgataccagt ccttaatgac caaaaattga atttgtttgc tttctaaaaa tttttcatag
    41521 cccatgacag agtagaaaga ataatggggc tccaaaatca agcaaataca ctgttcaatt
    41581 ccgtctgctt ccatttgacc gatcacatct ggaataaagg gactggaaaa cttattagca
    41641 aagtagacac tgtattcatt ccccagccta gcttctacca aggcaacctc ttgacgggta
    41701 attttttgca gaggcgtgcc tccaattcgt acataattat catagagagt ctgaatctcg
    41761 tggtcttggg gtctcacccc acgacgaata tttgtgaaaa aatcagctac accttcaaag
    41821 gtaatctctt ctggtgaacc gaaggtcatc attaaaattg cttttttcat gactgcttcc
    41881 ttgtgatgtt tttatcaagt ttattttatc attaattcat cgataagtaa acgctaacat
    41941 agggacattc tcaatcttct gtcttttgtt tttctcttct ttctatgata caatggaaaa
    42001 aataaattca aaaggagttt ttttatgact tatccaaatc tcttggaccg cttcttaacc
    42061 tacgttaagg tcaacacgcg ctctgatgaa cactctacta ctactccaag tacacagagt
    42121 caggttgact tcgcaacaaa tgtcctaatt cctgaaatga aacgtgttgg actgcaaaat
    42181 gtttactatc taccgaatgg ttttgctatt ggaaccttgc cagccaacga tccgtcttta
    42241 acacgtaaga ttggttttat atcgcacatg gatactgctg attttaatgc tgaaggagtc
    42301 aatccacagg taattgaaaa ctacgatggt ggtgtgattg aactagggaa ttctggtttc
    42361 aaactcgatc cagctgactt caagagtctt gaaaaatatc caggacaaac gctcatcaca
    42421 acagatggaa caaccttgct aggtgctgat gacaagtcag gaattgctga aattatgaca
    42481 gccattgaat atctaactgc tcatcctgaa attaagcact gtgagattcg tgttggtttt
    42541 ggtccagatg aagaaatcgg tgttggtgcc aataaatttg atgcagaaga ttttgatgtg
    42601 gattttgcct acactgttga tggtggtcca ctaggtgaac ttcagtacga gactttctca
    42661 gccgctggtg ctgaattgca tttccaaggc cgtaatgtcc accctggtac tgccaaaggg
    42721 cagatggtca atgcccttca gctagcaatt gattttcata atcaacttcc agaaaatgac
    42781 cgacctgagt taactgaagg ttaccaaggt ttttaccatc taatggatgt gacaggtagt
    42841 gttgaggagg cgcgtgcaag ctacatcatt cgtgattttg aaaaagatgc ctttgaagcg
    42901 cgtaaagcat ccatgcaatc tatcgctgat aagatgaatg aagaacttgg gagcaaccgt
    42961 gtcactctca acttgacaga ccagtactac aatatgaaag aagtcattga aaaagatatg
    43021 actccaatta ccattgctaa agccgttatg gaagatctag gtatcacgcc tattatcgaa
    43081 ccaatccgag gtggaacaga cggctctaag atttccttta tgggaatccc aactccgaat
    43141 atctttgcag gtggcgaaaa tatgcacgga cgttttgaat acgttagcct tcagactatg
    43201 gaacgtgcag ttgataccat cattggcatc gtagcttata aaggctaaaa agacgaggta
    43261 gctcagctac ttcgcctttc tttttattct actggttttt cttgatttcc agtagttgta
    43321 gaagattctg ttgtttcatt ttctgaagtt gattcagcag gtttagaatc tcttgtattg
    43381 cttggtttgt tttcgtcgct agcagtttca atgttagatt ctgcagttgc gtttggttgg
    43441 ttctcagcac tggtgttatc actatttgct tcagcatttc ttgctggact tgtttcttca
    43501 cttgcgctag cttttgactg gatttgatga ttcaaaacta gaatagcttt tgtcgattca
    43561 agtaaagctg ttttgtcttt actcttagca gaaagttgat ctaataatgc atccacctta
    43621 tcaaagtccg catcagatcc attattactt tctaaataag agtgaagcga catgagaata
    43681 tcgtagagtt tttgatagag tacaagtgtc tgagaatctt gctcagcatt ttccttttct
    43741 tgttgaaggg cgctagcgat acgagtcaaa acatctttta cctgactgtt tacttcatcc
    43801 aagtctgcat cagccttgtt tgtggcagct tttagatttt ctacttcttc tgccaaggat
    43861 tgtctgattc cttcttcatg gatttgttcc aagagttgat ttgccttgct caaaagactt
    43921 tctacttctt ccttgctatc tgtcgcagat tattggttgc tatctaccat gtactcctaa
    43981 aacaggagag ttataatcca agattacaag gccttacaga aataagaaat ccagataaga
    44041 caatgttcgt ccaagacgct attcgcttcg cacaacagca cggattcaat atgctttaat
    44101 tttaaagttt aggtgtcaag acctcttttt agtgtgccca aaatttagag aagtaatcaa
    44161 tcaactaact tttatttttt tcaaactttc agtaaactga cctaaagcta actcaatctg
    44221 tctttgtaga tgcttctgct atcagctaga agttgatcta cttttgccaa gactgccttc
    44281 tcatcaaaag ttccaggttg atagttggat tgcagggatg gaatcttgtt tttcaaagcc
    44341 gcttcatatc ccttagtttg aaccttgatg tagtgattgt ggtcgccatg aggaatcaca
    44401 aaaccttctg aatcttcact tataattcga ttggcatcaa aaccatgacc atcttcttcc
    44461 tcatggtgga catgtagtga cggattactt aatacagaac tagaagaact tcctgcctct
    44521 tccgtgttag agtgtgatgg gggattgtta agagatgact taggaatata gtgatagtga
    44581 tccccatgtc ttactatata agcatcacct gtatctctga caatatcatt agggttaaag
    44641 acatatgtgg ctgctaattc acctgccgac aagtcactct caggaatgaa atgatagtga
    44701 ccaccatgtg gtactatagt agattgaaat agaatatgag caaattgata aggggatttt
    44761 aaagtaattt ctaacaatga tttagaaact atgatgtgct attctaaatt caactcacta
    44821 tatataacca tcatcggtag tataacgtcc ctgtaatttt gctacagata cttctgcact
    44881 agctccttta tcctctttac catgttcttg tttttggcga ttgatttcat cttttgttcg
    44941 tacattttct gcatgagctt gatctttaag gtaaacataa tactttccat ctaccttaat
    45001 actatatcct cccttaacct aactgacgat atcttgatct ttcggctgat agttgggggc
    45061 tttcattaat ggctcttcac taaagagcgc atcaaaagga actttaccat tatagcagtg
    45121 ataatgatcg ccatgagaag ttacataacc ttgacctgta atcttaataa caatttgttt
    45181 tgcttgaatt ccttcttttt gactaaccta gtctggagtc aaattttcag tcttcttagt
    45241 gtctttatta ctgtttacat atgaaacacg atttttatct gtattggtct gttagctatg
    45301 ttggttcaga gcataaacac acagacttaa ggaaaggata acagcagatc cagctgctat
    45361 atatttcttt ttaaatttca taattacctc atttctataa ttatttatat gatgtcttca
    45421 ttattaaatg attaaataaa ttaattaact agtaaatatt ccacctcttt ttaagttgta
    45481 tgtcaagaaa ttttatatat taataataaa atgaaattct cccaaagtca gagttttatt
    45541 tctaactttt gagagaactt catttttgat tcagactttt tctactgcta ttccttacgc
    45601 tatgagatca gataaattct tttttatcac ttctccactt ggcaatctta attcaatcgt
    45661 tccatccata ttgaatataa cactatctaa gcctaatccg taaccagctg taaatttttc
    45721 taatttttct tgtacaggat ctactgctgg agcttcctct aatgctggat ctaacatagg
    45781 gtcactcccc acattccctt ctggattcaa cattccatta tccgttgagt tttctggttt
    45841 tacaggtttt tcgtttggtg cctctggtaa agaatctgct ggtttatttt ctgttggttg
    45901 gttctcaact gttccagtag atacttttcc attttcagat ggtttatttt caccatttcc
    45961 ttgaggtgct tctcctgtaa aatctgccat attcttttta atgacttctc ccgatggtaa
    46021 atataattca attgttccgt ccatattaaa caagacattt tctagcttca tcccataact
    46081 ttcagcaaat tttgctactt tttcttgtac aggatccact gtaggaactt cttctaacgt
    46141 tgaattacta gtactattcc cagtttcaga aagtttttct ttttctacct tctcactagt
    46201 ctttggttct tctacctttt catcaagttt tgagttttct tgtgctttat tccttttaaa
    46261 ttgtggtaga atacttggtt tatcagtttg attttctttt tccaagatag gtacttccac
    46321 aatataagtc gattgattgt ccaaataagc atttgccatg aaggttacag gaattttatt
    46381 tccggccgtt ctggttgttc cttggtttaa tttcggaatc ggtaatttga tttcaccaac
    46441 tttatagtta ttttctaaat aagcatttcc atgaaattca tcaaacactc tgactaaagc
    46501 atcagttcct ttaggcactg caaattgagg gttcactctt aaataagtat cccctgcatg
    46561 gaaaggatag aaaatcgttt gactggccat tttgtaagct aaagaggttg gaactgtaaa
    46621 tgtaccatca taacttactt ctggataatc ttttgaagcg atagtatact taaatgtttg
    46681 tcctggtaaa taaggctgat ctaattcaaa gtttgcaata ttccctactc cttctccaaa
    46741 tactttacca gatactttct ccaatacttt tccatctggt gttattaatt ttactagcat
    46801 attgatacct aattttttct ccaattcagg cggaaaacta aaagaaacgc gtttttgacc
    46861 attggctaga gtaaagtttt gattattaaa cgtactattt tttaacaaat taacaacatt
    46921 cgttaattct tctccagtat aaactttatt cccttctttt ttagcaactc cttcttcggg
    46981 tttaaacagt tcatagttac tgtgagaatg accaattcca accggtttat gttcatcaat
    47041 cggatctgca tgatgatgat ctccatgcgg ataaataatc gcattttttt ctttattcac
    47101 gacaatactt tcacgtttga caccatattg tttcataatg ccagcaattt tttcttcgat
    47161 ttttttatct aaatctttca tttctttggc attacctgga taatcctgtt catgagatga
    47221 caaagaatct aatccattat gactagtttt aacttcctct aaatgttttt gcgcagcttt
    47281 aatttgctct tctgtcaagt ccttcttgaa gaagtaatga ttatgattac cgtgactcat
    47341 gataaatcct gattcatctt cagcgataat acgattagca tcaaatccgt atccatcttc
    47401 ttcatgtttc tcatgtgaaa ttcctggatt gattggaaga gatggagaag gtgttgctag
    47461 actattgttt ggaagagtcg gttgcccaat ttgatttgat tttggaatgt aatggaaatg
    47521 atcaccatgt cttacaatat aagctgtagc cgtttcttca acgatatctt ttggattaaa
    47581 aatataacca tcagatgctg aagagagctc cttacttgtc gttaaagaag aaggattgct
    47641 tgaaagactg cctagactag acactacttc attaggtttt gcatttgtag aaactgtaga
    47701 accagttcca ctgataggca ccattctggc aatcttttct tctaaggcag aaagcttgct
    47761 gtaaggaata aagtggtaat ggtcgccatg cggaatcgca actccatttg gtgtacgact
    47821 gataatctta gcagggtcaa agaccaggcc atctgattca ctgtaacgtt gggcgctagg
    47881 tgaatcatag agttccttca aaagactctg gagattttca gatttatttg ctggcttgct
    47941 agttgatcct tttgctacag attgcgtgtt attgtcacta gctgttgaag aatagcttaa
    48001 ctgactcggt tgcatatttt ttccagccag atgtgcttta gctgctgcta attcactagc
    48061 agataaatcg cttttgggaa tgtagtgata gtgacctcca tgaggaacga tataagcatt
    48121 acccgtatct tcgataatat cagctggatt aaagacataa ccatcatttg tcgtatatcg
    48181 tccctgagac cttgctacag caacattaga gttaaccttc tcattatctt tgacatgttc
    48241 ttgtttttga cgattgattt catctttagt tcgaacatta tcagcatgag ctgcatcttt
    48301 caggtagaca taatattttc catcgacctt gatgatataa ccacccttga cttcattgac
    48361 aatatcagcg tctttaagtt gatagtttgg atccttcatc aagagttctt cactaaagag
    48421 ggcatcataa ggaactttcc cattatagta atgatagtgg tcaccgtgtg acgttacata
    48481 gccctgatct gtaattttga ttacaatttg ctcggcctga attccttctt tctggctaac
    48541 ctggtctggt gtcaagtttt cacttttctg acttgactgg ctgccatcta cataagagac
    48601 acgattattg tccttatttt cctgcgaacg atgctggttt agtgcatagg cacatagact
    48661 caaggatacg ataacagctg atccagctgc tatatatttt ttactgaatt tcataaatcc
    48721 ctcatttcaa taaatgatga agttttttct caacttcttt tactttatta aatagttttc
    48781 taaaccggtt atttaaccat ttaattaacc agtaaatagt ttactattta aaattacttt
    48841 tgtcaagttt ctgttacgtt tttctaaaaa agagaagtaa cacgaaaggt tacttctcca
    48901 taaaatatgc tccattcatt ttactactgt ataggagtcg gttgactttc ttttaacaaa
    48961 gccaagagac tatctacttc tgctgaaata gtgttattat ctttcgttcc gagaagaaga
    49021 ctacttttta gaccagtcaa tgtctccaca gcattttgtc taatactaga atctgttact
    49081 ttttctagca aggcctccgc ctctgctatc ttagcgttaa taacagaatg ctctacttga
    49141 ggaatttcag cctcatctgt agtatcttca gcttcttcct ctgtctcttc cgtatcagtg
    49201 cttggtttat aaagattatc tgctgaagga tttaaaccag cgtgattctc tttttcatca
    49261 gattcagggt gagttggctc acttacttca tcatgttcct tatcttcctc aggtttactg
    49321 tcttggtctg ccttattttt a
//
LOCUS       DAVHBD010000011        48290 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000011 DAVHBD010000000
VERSION     DAVHBD010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48290
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.011"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            9..89
                     /locus_tag="VVK04_000650"
     tRNA            9..89
                     /locus_tag="VVK04_000650"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="VVK04_000651"
     tRNA            94..164
                     /locus_tag="VVK04_000651"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="VVK04_000652"
     tRNA            179..251
                     /locus_tag="VVK04_000652"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            262..333
                     /locus_tag="VVK04_000653"
     tRNA            262..333
                     /locus_tag="VVK04_000653"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:294..296,aa:Gln,seq:ttg)
     gene            343..426
                     /locus_tag="VVK04_000654"
     tRNA            343..426
                     /locus_tag="VVK04_000654"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:377..379,aa:Leu,seq:caa)
     gene            533..1810
                     /locus_tag="VVK04_000655"
     CDS             533..1810
                     /locus_tag="VVK04_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU3989344.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEFIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1886..3370
                     /locus_tag="VVK04_000656"
     CDS             1886..3370
                     /locus_tag="VVK04_000656"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU3989345.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNALNTQGQYELTDFDVEILELFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3431..4711
                     /locus_tag="VVK04_000657"
     CDS             3431..4711
                     /locus_tag="VVK04_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU3989346.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4715..5335
                     /locus_tag="VVK04_000658"
     CDS             4715..5335
                     /locus_tag="VVK04_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU3989347.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKNLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLDPEKTY
                     YIGDRTLDVEFAKNSGIQSINFLESSFEGNHRIQALADIPHIFESK"
     gene            5501..6643
                     /locus_tag="VVK04_000659"
     CDS             5501..6643
                     /locus_tag="VVK04_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU3989348.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVFWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPPAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6966..7391
                     /locus_tag="VVK04_000660"
     CDS             6966..7391
                     /locus_tag="VVK04_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU3989349.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7402..7761
                     /locus_tag="VVK04_000661"
     CDS             7402..7761
                     /locus_tag="VVK04_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU3989350.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            7890..8486
                     /locus_tag="VVK04_000662"
     CDS             7890..8486
                     /locus_tag="VVK04_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU3989351.1"
                     /translation="MSPFEAIKGLPAEIHGAEVRWLEVPTVFHKSAQVLEEEMNRYQP
                     DFVLCIGQAGGRTSLTPERVAINQDDARTSDNEDNQPIDRPIRPDGASAYFSSLPIKA
                     MVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFSYVKAGFMHIPYMMEQVVNR
                     PTTPAMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(8514..9371)
                     /locus_tag="VVK04_000663"
     CDS             complement(8514..9371)
                     /locus_tag="VVK04_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU3989352.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLAGLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9501..10643
                     /gene="tgt"
                     /locus_tag="VVK04_000664"
     CDS             9501..10643
                     /gene="tgt"
                     /locus_tag="VVK04_000664"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU3989353.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQSLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10741..12558
                     /locus_tag="VVK04_000665"
     CDS             10741..12558
                     /locus_tag="VVK04_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU3989354.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPSYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHRMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12711..13862
                     /gene="nagA"
                     /locus_tag="VVK04_000666"
     CDS             12711..13862
                     /gene="nagA"
                     /locus_tag="VVK04_000666"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU3989355.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14025..15083
                     /locus_tag="VVK04_000667"
     CDS             14025..15083
                     /locus_tag="VVK04_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU3989356.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15234..15599
                     /locus_tag="VVK04_000668"
     CDS             15234..15599
                     /locus_tag="VVK04_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU3989357.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15674..16615
                     /locus_tag="VVK04_000669"
     CDS             15674..16615
                     /locus_tag="VVK04_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU3989358.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16563..17579
                     /locus_tag="VVK04_000670"
     CDS             16563..17579
                     /locus_tag="VVK04_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU3989359.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17581..17907
                     /locus_tag="VVK04_000671"
     CDS             17581..17907
                     /locus_tag="VVK04_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEU3989360.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            17900..18304
                     /locus_tag="VVK04_000672"
     CDS             17900..18304
                     /locus_tag="VVK04_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU3989361.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18309..18569
                     /locus_tag="VVK04_000673"
     CDS             18309..18569
                     /locus_tag="VVK04_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989362.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18532..18993
                     /locus_tag="VVK04_000674"
     CDS             18532..18993
                     /locus_tag="VVK04_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU3989363.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            18971..19417
                     /locus_tag="VVK04_000675"
     CDS             18971..19417
                     /locus_tag="VVK04_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU3989364.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            19520..20114
                     /locus_tag="VVK04_000676"
                     /pseudo
     CDS             19520..20114
                     /locus_tag="VVK04_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20175..21128
                     /locus_tag="VVK04_000677"
     CDS             20175..21128
                     /locus_tag="VVK04_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU3989365.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGIGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21179..22369
                     /locus_tag="VVK04_000678"
     CDS             21179..22369
                     /locus_tag="VVK04_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU3989366.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIRKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22518..22889
                     /gene="rnpA"
                     /locus_tag="VVK04_000679"
     CDS             22518..22889
                     /gene="rnpA"
                     /locus_tag="VVK04_000679"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU3989367.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYVEMEKNLLH
                     VLKLSKIYREGNGSEKETNVD"
     gene            22858..23688
                     /locus_tag="VVK04_000680"
     CDS             22858..23688
                     /locus_tag="VVK04_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU3989368.1"
                     /translation="MGVKKKLTLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLV
                     YFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQ
                     YPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGH
                     FLWINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVY
                     APGGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK
                     "
     gene            23707..24693
                     /locus_tag="VVK04_000681"
     CDS             23707..24693
                     /locus_tag="VVK04_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU3989369.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVNLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24744..25367
                     /locus_tag="VVK04_000682"
     CDS             24744..25367
                     /locus_tag="VVK04_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU3989370.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25498..26955
                     /locus_tag="VVK04_000683"
     CDS             25498..26955
                     /locus_tag="VVK04_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU3989371.1"
                     /translation="MEVVSNVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            26978..27259
                     /locus_tag="VVK04_000684"
     CDS             26978..27259
                     /locus_tag="VVK04_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU3989372.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27336..27821
                     /locus_tag="VVK04_000685"
     CDS             27336..27821
                     /locus_tag="VVK04_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU3989373.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELDDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27838..28503
                     /locus_tag="VVK04_000686"
     CDS             27838..28503
                     /locus_tag="VVK04_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU3989374.1"
                     /translation="MTKKIPNLQVALDHSDLQGAIKAAVSVSQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28507..29370
                     /locus_tag="VVK04_000687"
     CDS             28507..29370
                     /locus_tag="VVK04_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU3989375.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVELSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLVIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29372..30076
                     /locus_tag="VVK04_000688"
     CDS             29372..30076
                     /locus_tag="VVK04_000688"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU3989376.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVTYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINLRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30255..31928
                     /locus_tag="VVK04_000689"
     CDS             30255..31928
                     /locus_tag="VVK04_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU3989377.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32040..33131
                     /gene="ulaG"
                     /locus_tag="VVK04_000690"
     CDS             32040..33131
                     /gene="ulaG"
                     /locus_tag="VVK04_000690"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU3989378.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33245..35221
                     /gene="tkt"
                     /locus_tag="VVK04_000691"
     CDS             33245..35221
                     /gene="tkt"
                     /locus_tag="VVK04_000691"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU3989379.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYTDFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGENIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35338..35637
                     /gene="yajC"
                     /locus_tag="VVK04_000692"
     CDS             35338..35637
                     /gene="yajC"
                     /locus_tag="VVK04_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU3989380.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35684..36112
                     /locus_tag="VVK04_000693"
     CDS             35684..36112
                     /locus_tag="VVK04_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU3989381.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36114..36524
                     /locus_tag="VVK04_000694"
     CDS             36114..36524
                     /locus_tag="VVK04_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989382.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36824..39475
                     /gene="adhE"
                     /locus_tag="VVK04_000695"
                     /gene_synonym="adhC"
     CDS             36824..39475
                     /gene="adhE"
                     /locus_tag="VVK04_000695"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU3989383.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRKLAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(40461..40769)
                     /locus_tag="VVK04_000696"
     CDS             complement(40461..40769)
                     /locus_tag="VVK04_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU3989384.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(40766..41074)
                     /locus_tag="VVK04_000697"
     CDS             complement(40766..41074)
                     /locus_tag="VVK04_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU3989385.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(41079..42374)
                     /locus_tag="VVK04_000698"
     CDS             complement(41079..42374)
                     /locus_tag="VVK04_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU3989386.1"
                     /translation="MKSSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(42392..43801)
                     /locus_tag="VVK04_000699"
     CDS             complement(42392..43801)
                     /locus_tag="VVK04_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU3989387.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPEKLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            43959..44687
                     /locus_tag="VVK04_000700"
     CDS             43959..44687
                     /locus_tag="VVK04_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU3989388.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45146..45340
                     /locus_tag="VVK04_000701"
     CDS             45146..45340
                     /locus_tag="VVK04_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU3989389.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(45706..47016)
                     /locus_tag="VVK04_000702"
     CDS             complement(45706..47016)
                     /locus_tag="VVK04_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU3989390.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47253..48125
                     /locus_tag="VVK04_000703"
     CDS             47253..48125
                     /locus_tag="VVK04_000703"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU3989391.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT        14764 a         8607 c        10530 g        14389 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttggggtata gccaagcggt aaggcaaggg actttgactc
      301 cctcatgcgt tggttcgaat ccagctaccc cagttactat ttgccggcgt ggcggaattg
      361 gcagacgcgc tggactcaaa atccagtgtc cgcaaggacg tgccggttcg accccggccg
      421 ccggtatagt atagtgttag gaacgttgtt attcttcgtt ccttttttat attatttttg
      481 gtataattat agttattcaa attttattta gattaagaaa gtgtagggga gtatgtcttg
      541 ttctatcgat ttattaaaac atcggtattt gaaaaatatt aaagaaaatc ctgaattgtt
      601 tgtcggaatt gagttggagt atcctgttgc aagtttagaa ggggatgcta cagatgttga
      661 agttataaag gatctatttc attatttagt ttctactttg gatctcaccg tagcaaaggt
      721 agatgatttt ggcaatctga tccagttagt agatccgata agtcaggatg ctattttatt
      781 tgaagtttcc tatacaacga ttgagtttgc atttggtaag gctgaaacga ttcaagaggt
      841 cgaaaatcgt ttcaataatt atatgaatgt aattcagaga aagttagctg aatcaaatca
      901 tgctattgtt ggctgtggta tccatcccaa ctgggataaa aatgagaatt gtccagtggc
      961 ttatccacgc tatcagatgt tgatggatta tttgaatttg agtagaaata ttattaaatc
     1021 agatttacat catttccctg aatatggtac ttttatctgt gggagccagg ttcagctgga
     1081 tatttcaaaa accaactact tacgggtgat taatgctttt actcaaattg aagcggctaa
     1141 ggcttattta tttgcaaact ctgagttttc gggtgcggat tgggatacga aaatttcaag
     1201 ggatattttc tgggaagaat ctatgcatgg tatctatcca gagaatgttg gggtcaatgc
     1261 tagactcctt aatgatgaag ctgatttttt tgactatcta aatcattctg cgatttttac
     1321 tgcggaacgt gatgggcaga cctattattt ttatcctatt caggctgggg actatttggc
     1381 tacgcctgaa atccaagcat tttctctgaa tggggatgag tttattattt acccccaaga
     1441 gaaggatttt gaaactcatc gtagttacca gtaccaagac ttaacgactc gaggaacagt
     1501 tgagtttcgt agtgtgtgta cacagccact tgatagaact tttgcttctg cagcttttca
     1561 cttgggatta ttggttaatt tagacaagtt agaagcttac ttagaaacag cacctttctt
     1621 taaagtattt ggttatgatt acaagtcttt aaggagacaa ttttctaaga aaaatcttac
     1681 agatgaggaa gaaactacga ttattgaatt ttccaaagac ttactcctac tagctgagga
     1741 gggactagtg gtgagaaata aggaagaaat gacctattta cagcctttga gagaagaatt
     1801 gagcctataa tttctcttat aaagggagaa ttttctgaaa aatcatgata taatggacga
     1861 gactatagat aaaggataga gagtaatgac attagtttat caatcaacgc gtgatgccaa
     1921 caatacagta actgccagtc aagcaatttt gcaaggtttg gcgacggacg gcggtttgtt
     1981 tacaccggtt acttatccaa aggtagattt ggactttgac aaattgaaag atgcttctta
     2041 ccaggaagtt gctaagctag ttttgtcagc atttttagat gactttacag ctgaggagtt
     2101 ggactactgt atcaacaatg cctacgatag caaatttgat actccagcta ttgcaccatt
     2161 agtgaaatta gatgggcaat acaatttgga acttttccat ggttcaacga ttgcctttaa
     2221 ggatatggcc ttgtctattt tgccatactt tatgacgact gctgctaaga aacatggttt
     2281 ggagaacaag attgttatct tgacagcgac atctggtgac acggggaaag ctgctatggc
     2341 ggggtttgcg gatgtgcctg gtactgagat tatcgtcttt tatccaaagg atggtgtcag
     2401 caagattcaa gagttacaaa tgaccactca gactggcgac aatactcatg ttattgctat
     2461 tgatggtaac tttgacgatg cgcaaacaaa tgtgaagcac atgtttaacg atgtggctct
     2521 tcgtgaaaaa ttgactacca acaagttgca attttcatct gctaactcta tgaatatcgg
     2581 tcgtttggtg ccacagattg tttattatgt ttatgcctat gctcagttgg tcaagactgg
     2641 tgagatcgtg gctggtgata agattaactt cacagtacca acaggaaact ttggaaatat
     2701 cttggctgcc ttttatgcca aacaaatcgg tctcccagtt ggtaaattga tctgtgcttc
     2761 aaatgataac aatgttttga cagacttctt caagacacgt gtttacgaca agaaacgtga
     2821 gtttaaggta acaaccagcc catctatgga tatcttggta tcttcaaact tggagcgttt
     2881 gattttccat cttttgggga atgatgcggt taagacggct gaactcatga atgccttgaa
     2941 tacacaagga caatatgaac tgactgattt tgatgtagag attctggagc tctttgcagc
     3001 tgaatatgcg actgaggaag aaacagcggc agaaatcaag cgtgtttatg agtcagattc
     3061 ttatattgag gatccacata cggcggttgc ctcagcagtt tatagaaaat accaagcggt
     3121 tactgatgat gcgactaaga cagtgattgc ttcaacagct agtccctaca agttcccagt
     3181 agttgcagta gaagctgtaa ctggaaaagc aggtttaaca gactttgaag ccttggctca
     3241 attacatgaa atctcaggcg ttgcagtgcc accagcagtt gatgggcttg aaatagctcc
     3301 aattcgtcac aagacaacag tggcagctgc tgacatgcaa gcagcggttg aggcttattt
     3361 aggactttaa gacagaggga gcaaactcgg ttgggaaact aactgagttt cttttcatca
     3421 ggaggagaga ttgtttaaga aaaataaaga cattcttaat attgcattgc cagctatggg
     3481 tgaaaacttt ttgcagatgc taatgggaat ggtggacagt tatttggttg ctcatttagg
     3541 attgatagct atttcagggg tttcagtagc tggtaatatt atcaccattt atcaggcgat
     3601 tttcatcgct ctgggagctg ctatttccag tgttatttca aaaagcatag ggcagaaaga
     3661 ccagtcgaag ttggcctatc atgtgactga ggcgttgaag attaccttac tattaagttt
     3721 ccttttagga tttttgtcca tcttcgctgg gaaagagatg ataggacttt tggggacgga
     3781 gagggatgta gctgagagtg gtggactgta tctatctttg gtaggcggat cgattgttct
     3841 cttaggttta atgactagtc tgggagcctt gattcgtgca acgcataatc cacgtctgcc
     3901 tctctatgtt agttttttat ccaatgcctt gaatattctt ttttcaagtc tagctatttt
     3961 tgttctggat atggggatag ctggtgttgc ttgggggaca attctgtctc gtttggttgg
     4021 tcttgtgatt ttgtggtcac aattaaaact gccttatggg aagccaactt ttggtttaga
     4081 taaggaactg ttgaccttgg ctttaccagc agctggagag cgacttatga tgagggctgg
     4141 agatgtagtg atcattgcct tggtcgtttc ttttgggacg gaggcagttg ctgggaatgc
     4201 aatcggagaa gtcttgaccc agtttaacta tatgcctgcc tttggcgtcg ctacggcaac
     4261 ggtcatgctg ttggcccgag cagttggaga ggatgattgg aaaagagttg ctagtttgag
     4321 taaacaaacc ttttggcttt ctctgttcct catgttgccc ctgtccttta gtatatatgt
     4381 cttgggtgta ccattaactc atctctatac gactgattct ctagcggtgg aggctagtgt
     4441 tctagtgaca ctgttttcac tacttgggac ccctatgacg acaggaacag tcatctatac
     4501 ggcagtctgg cagggattag gaaatgcacg cctccctttt tatgcgacaa gtataggcat
     4561 gtggtgtatc cgcattggga caggatatct gatggggatt gtgcttggtt ggggcttgcc
     4621 tggtatttgg gcagggtctc tcttggataa tggttttcgc tggttatttc tacgctatcg
     4681 ttaccagcgc tatatgagct tgaaaggata ggaaatgcaa aaaacagctt ttatttggga
     4741 tttagacggg actttattgg actcttacga agcgatttta tcagggattg aggagacttt
     4801 tgctcagttt tctattcctt atgataagga gaaggtgaga gagtttatct tcaagtattc
     4861 ggtgcaaaat ttgcttgtgc gggtggcaga agatagaaat ctggatgttg aggtgctaaa
     4921 tcaggtgcgt gcccagagtc tggctgagaa gaatgctcag gtagttttga tgccaggtgc
     4981 gcgtgaggtg ctagcttggg cagacgaatc aggaattcag cagtttatat atactcataa
     5041 ggggaacaac gcttttacca ttctcaagaa cttgggggtg gaatcctatt ttacagagat
     5101 tttaaccagt cagagtggct ttgtgcggaa gccaagtcca gaagcggcta cctatctgct
     5161 agataagtat cagctggatc ctgagaagac ctattatata ggggaccgga ctttagatgt
     5221 ggaatttgcc aagaatagcg gtattcaaag catcaacttt ttagaatctt cttttgaagg
     5281 caatcacagg attcaagcac tagcagatat tcctcatatt tttgagagta agtaacgaga
     5341 agattgtgtc agttttgtga cagaaaccta acaaactatt tcaagtaatc gagtttgtta
     5401 caaggaatag acagttctgt taaataggcc cgagagggct ttttttctac attttttgtg
     5461 ttatcataga caggtactca tttgaaagga atttgaaaga atgaagaaaa gaatgttatt
     5521 agcgtcaaca gtggccttgt catttgcccc agtattggca actcaagcag aagaagtttt
     5581 ttggactgca cgtagtgttg agcaaatcca aaacgatttg actaaaacag acaacaaaac
     5641 aagttataca gtacagtatg gtgatacttt gagcaccatt gcagaagcct tgggtgtaga
     5701 tgtcacagtg cttgcgaatc tgaacaaaat cactaatatg gacttgattt tcccagaaac
     5761 tgttttgaca acgactgtca atgaagcaga agaagtaaca gaagttgaaa tccaaacacc
     5821 tcaagcagac tctagtgaag aagtgacaac tgcgacagca gatttgacca ctaatcaagt
     5881 gaccgttgat gatcaaactg ttcaggttgc agacctttct caaccaattg cagaagctcc
     5941 aaaagaagta gcatcaagtt cagaagttac aaagacagtg attgcttctg aagaagtggc
     6001 accatctacg ggcacttctg tcccagagga gcaaacggcc gaaacaactc gcccagttga
     6061 agaagcaact cctcaggaaa cgactccagc tgagaagcag gaaacacaag caagccctcc
     6121 agctgcatca gcagtggaag caactacaac aagttcagaa gcaaaagaag tagcatcatc
     6181 aaatggagct acagcagcag tttctactta tcaaccagaa gagacgaaaa taatttcaac
     6241 aacttacgag gctccagctg cgcccgatta tgctggactt gcagtagcaa aatctgaaaa
     6301 tgcaggtctt caaccacaaa cagctgcctt taaagaagaa attgctaact tgtttggcat
     6361 tacatccttt agtggttatc gtccaggaga cagtggagat cacggaaaag gtttggctat
     6421 cgactttatg gtaccagaac gttcagaatt aggggataag attgcggaat atgctattca
     6481 aaatatggcc agccgtggca ttagttacat catctggaaa caacgtttct atgctccatt
     6541 cgatagcaaa tatgggccag ctaacacttg gaacccaatg ccagaccgtg gtagtgtgac
     6601 agaaaatcac tatgatcacg ttcacgtttc aatgaatgga taaacccgac ttgataacat
     6661 cattttgacg aatgagatct agctttcgtg atggaaagcg attctcgttc gttttttctt
     6721 tgtcatactc ttcgaaaatc tcttcaaacc acgtcagttt tatctgaaac ttcaaagctg
     6781 tgctttgagc aacctgcgac tagcttccta gtttgctttt tgattttcat tgagtatcaa
     6841 tttgaatgga aaatggaaag ttatcatctt gtaatgagtt aagcaacatt cttgcaatct
     6901 attttacttt atatcacaat taattagtca aatattgata aatcaataaa aagagagggg
     6961 aagaaatgct agagattcaa gatttactgt atcaactccg cttgtctgag caagcgagta
     7021 cgcaattgtt tgaaaaaagg cttgggatta gtttgacacg gtatcagatt ttactgtttt
     7081 tgctggagca ttctccttgt aaccaaatgg cggttcagga gcgtttgaaa attgatcagg
     7141 ctgctttgac acggcatttc aaaattttgg aaacggaagg tttggtggag cgtcatcgta
     7201 atcctgaaaa tcagcgggaa gtgttggtag aggctgcgaa gtatgccaag gagcagttag
     7261 tggtgaatcc ccctctgcaa catatcaggg ttaaggaaga gatagaaagt atcttaacag
     7321 agtttgagag aacagaactc agccgtttat taaataaatt ggttttgggt attgaaaata
     7381 tagaaattta aggagaaata gatgtcaatt attttaacaa cgatcgttgc tttggagcat
     7441 ttttacattt tttatttgga aagtattgcc acgcaatcag atgcgactag tcgtgtattt
     7501 aatatggaaa aggaagaatt ggctcatccg tcagtaagtt cattgttcaa aaatcaaggg
     7561 atttataagg ctctgctagg agtctttctc ttgtatggca tttatttctc acagaattta
     7621 gaaattgtga ctatttttgt cttatttgtg attggtgctg cgacttacgg ctctttaaca
     7681 gcggataaaa aaattatttt gaagcaaggt ggatcagcta ttttggcctt gattagtatt
     7741 ttactcttta aatacacttg aaggtcgatt ctaatctcgc taatcctttt taatccagaa
     7801 taagggaaat atgttatact tgtttttaag aaaaaagttt cattgaattg gttttgagga
     7861 gttagaaatg aaagtattag tgacaggttt tgagcccttt tgaggccatt aaaggtttac
     7921 cagctgaaat ccatggtgct gaggtccgtt ggctagaggt gccgacagtt tttcacaaat
     7981 ctgctcaagt attggaagaa gagatgaatc gttatcaacc tgactttgtc ctttgtattg
     8041 ggcaagctgg tggaagaact agtttgacac ctgaacgagt ggccattaat caagacgatg
     8101 cacgtacttc tgataacgaa gataatcaac cgattgaccg tcccattcgc ccagatggtg
     8161 cttcggccta ctttagtagt ttgccgatta aagcgatggt tcaagctata aaaaaagagg
     8221 gcttaccggc ctctgtttcc aatacggcag ggacttttgt ctgcagccat ttgatgtatc
     8281 aggctctcta tttggtagaa aagaaatttt catatgttaa ggcaggtttt atgcatattc
     8341 cttatatgat ggaacaggtg gtgaacagac cgactactcc agctatgagt ttagtggata
     8401 ttcggcgagg gatagaagca gcaatcggcg ctatgataga acatggagat caggaactca
     8461 agttggtagg cggagaaact cattgataga aaaaagcttg aggggaaaaa ccttcaagct
     8521 tttggacgtt ttcgagccaa tactgctcgg taaaacataa ttttagtgca ttggatataa
     8581 ggtaggagtg aaaaactagc aatgccaaag gtaatccaat tgaggaagta ccaaggaaga
     8641 agctgtaaat ctaggacaaa gcgctggaac ttgtagccct tcataaagga acggctagtt
     8701 tttaggattc gtcttggtgg gacctgtcct aggtctagac tataacagag aagaaattcc
     8761 acctgtgaat aggcataata ctgtggaata tagaggatat ttcctacaat gatcaagatg
     8821 agacctgcaa gaaagtagag tccaaagacc atgaggaaac gctcggtttc aactgatgag
     8881 agatctagat ttggaaactc aggatgtagg gtgacgaatt ttttggctaa aaagctacta
     8941 taaaagagga ggtaaatccc aagtaaatta gggatactcc ataaaaagag atagaaacgt
     9001 ttgagaagta gggtcaaaaa ggtttgagaa aagcgctcct catcaaagag agctaggctg
     9061 ttttttacag atggctccgt tttagaatct ttcatgagtg tcagtgttgc atagacggaa
     9121 ctggtcaaaa gaatagtccc gataaaggag actagtagag gaaagaggta ggcttgaagt
     9181 atttggccaa gtatgctgaa aaatggctgt tctaaaacag tcccgtggat ccgagataag
     9241 ggattaagaa aaccagataa gatgaccagc atactgggaa ggatatagag gagaaagaga
     9301 cggggggtgt cagcctgaaa atgttttgac tcctgacgaa ttgtttttaa atcaattttt
     9361 ggatagttca ttctcttatt ataccatagt tcttatacat agttcgtgac agttcctact
     9421 ttttttgata aaatcataca gtgtgtcctt gggcacactg tatgaactgg gactgtcttt
     9481 cccagcttcg gaggtaaaaa atgtcagatt caccaatcaa atatcgtttg attaagaaag
     9541 aaaaacacac aggagctcgt ctaggagaaa tcatcactcc ccacggtacc tttccgacac
     9601 ctatgtttat gccagttggg acacaagcca ctgtcaaaac tcagtcacct gaagaattga
     9661 aggagatggg ttcgggaatt atcctatcaa acacctatca tctctggctt cgccctggag
     9721 atgaactcat tgcacgcgct ggtggtctcc acaagttcat gaattgggac cagcctatct
     9781 tgacagatag tggtggtttt caggtttatt ctttagcaga tagccgtaat atcacagaag
     9841 aaggagtaac ctttaaaaat catctaaatg gttctaagat gttcctatcc ccagaaaaag
     9901 ccatctctat tcagaataat ctgggttcag acatcatgat gtcctttgat gaatgtcctc
     9961 agttttatca accttatgac tacgttaaga aatcgatcga gcgtaccagc cgttgggctg
    10021 agcgtggttt gaaggctcac cgtcgtccac atgaccaaag tttgtttgga attgtgcaag
    10081 gtgcaggatt tgaagacctt cgccgccaat cagctcatga tcttgtcagc atggatttct
    10141 caggctactc tatcggtggt ttggcagtgg gagaaaccca tgaagagatg aatgcggtct
    10201 tggactttac aactcaactg ctacctgaaa ataaacctcg ttatctgatg ggtgtgggag
    10261 cgccagatag cttgatcgat ggggtcattc gtggggtgga tatgtttgac tgtgtcttac
    10321 cgactcgaat tgctcgtaac gggacttgta tgaccagtca aggacgtttg gttgtgaaaa
    10381 atgcccagtt tgctgaggac tttacgccac tggatcctga gtgtgactgc tacacatgta
    10441 ataactatac acgcgcttac cttcgtcacc tgctcaaggc tgatgaaacc tttggtatcc
    10501 gcttgactag ctaccacaat ctttacttct tgcttaacct gatgaagcaa gtgcgacaag
    10561 ccatcatgga tgacaatctc ttggaattcc gtgagtattt tgtggaaaaa tatggctata
    10621 ataagtcagg acgtaatttc taaaatggaa ttgatataaa aaaatcctaa gttttctctt
    10681 aggatttttc ttcttttttt gatagaataa agtgtacaat gaaaggaaga ataaactcgt
    10741 atgcgcatta aatggttttc cttgattagg attataggtt tacttttggt actcttgtat
    10801 cacttctttc agacgatctt tcctggagga tttttcgggg tagatgtctt tttcacattt
    10861 tcaggtttcc tgattacagc tctactcatt gaagaatttt ctaagaacaa tgagattgat
    10921 ttgataggat tttttagaag acgcttttat cggattgtgc cacctgtggt tttgatggtc
    10981 ttggtgacca tgccttttac tttcttggtt cgccaagact atgttgctgg aattggtggc
    11041 cagattgcgg gcgtcttagg ctttatgacc aacttctatg aactcctaac aggtgggagt
    11101 tatgaatctc agttcattcc tcatttgttt gttcataatt ggagtttggc agttgaggtt
    11161 cactactata ttctttgggg attggcagtt tggttcttat ccaaacaagc taaatcaaat
    11221 ggtcagttga aggggatggt ctttctctta tctgctgctg ccttcttgat cagtttcttc
    11281 tccatgttta ttggtagttt tctagtgacc tcttattcct ctgtttattt ctccagttta
    11341 actcatgtct atccattctt tttgggaagt atgttagcaa ctattgtagg cgttcgtcag
    11401 acgacttccc tcgtcaagca gttggataaa atctgggatt tacgaaagac tttggtagtt
    11461 tttggaggag gctttggttt cctagttctt ttgactttct ttgtcaaatt cacttatctt
    11521 tttgcctatc ttatcggctt cttgcttgcc agtcttgcag ctcttgccat gattctggcg
    11581 gcgcgtgtct tacatgaaaa gacacatcat atacaggagc cgaagattat cagcttttta
    11641 gcggatacta gctatgcggt ttatcttttc cattggcctt cctatatcat tttctcacag
    11701 ttgacatcaa atcttcttgc tgtattactg actctgattt gttcttatgg ctttgccagt
    11761 ctgtcattct atgtattgga accttggatt gcaggcaaga acacacctat tttacaaact
    11821 cttcgtcccc tgccttatat tcacgcaatt cttgcagcag gtacaggaat cttgaccttc
    11881 attgtctgca tggtgacctt gttggcacca caagtgggag cgtttgagac agacttgact
    11941 gttaatggct tgaagcaagc tgcaacaaat attggccaga ccaaggtgat ggcagaacgg
    12001 gcagatgcaa acagtttggg aattgctgat ggcactatgt taattggtga ctcagtggct
    12061 ttaagggcaa atacagcact acagacagct cttcctggag cacagattaa cgcgcaggtc
    12121 agcgtaacaa ccaagaccgc aaatgaaatc atgctaaata atagccagaa taaattttta
    12181 cctaagacgg tggtcattgc gactggggta aataatcctg agaattacaa ggatgactgg
    12241 gacagtatcg tgaaaaatct tcctaaggga caccgtatga ttttggtgac tccttatgag
    12301 ggagataaga caaaagagac ctatgccatc gttgagaagg ctgctgccta tatgagagaa
    12361 ttggcagaga agacacctta cattacgata gcagattgga atcaagttgc gaaagagcat
    12421 ccagaaattt gggcaggaac agaccaggtt catttcggga gtgagagtag cactatcgaa
    12481 gcaggagcaa aattgtatgc agatacgatt gccacagctt tgcagacagc tcaagacaag
    12541 ccggttaaat caaaataact tgtattaaaa aagagaagag ttggagaaat ccagctcttt
    12601 taaaatatct ccaaaaaata ggtctatacc atttacaaat aaaaaagaaa ggtttataat
    12661 gtaattgaca taataaattg tagaatcaat cttttaagga ggttaacatt atgcctaact
    12721 atattaaagc ggatcagttt ttctacccac acggagttcg tcgaggtggt tacttggaac
    12781 ttgtggacgg caagtttggg aaacatgtag agcagattcc tgaaggggct gaggtgattg
    12841 actatacagg ttatagcatt gccccaggtc ttgtggatac tcatattcat ggatatgcag
    12901 gtgtagatgt gatggacaac aacattgaag gtacattgca tactatgagt gaaggacttc
    12961 ttagtaccgg tgttaccagt ttcttaccca caactttaac agccacttat gagcaattgc
    13021 ttgcagtcac tgaaaatctt ggaaaccatt ataaagaagc aacaggtgct aagattcgtg
    13081 ggatttatta tgaaggtcca tatttcacag aaacttttaa gggggcacaa aatccaactt
    13141 atatgagaga cccgggtgtt gaggagtttc attcttggca aaaagcggca aatggcttgc
    13201 ttaataaaat tgcccttgca ccagaacgtg atggggtgga agactttgtt cgtacagtta
    13261 cgggcgaagg tgtgacggtt gctcttggac attcaaacgc gacttttgat gaagccaaaa
    13321 aagcagtcga tgctggagcg agtgtttggg tgcatgccta caatggaatg cgtgggttga
    13381 ctcaccgtga attgggtatg gttggagcca tgtaccaatt gccacatacc tatgcagagt
    13441 tgatctgtga tggtcaccac gtagatccaa aggcttgcga aattcttatc aaacaaaaag
    13501 gaacagaaaa catcgctctt atcacagact gtatgacagc tgggggattg gaagacggag
    13561 attatatgtt gggagaattc ccagttgtcg ttgcaaatgg aactgcacgc ctcaaatcga
    13621 caggtaactt ggcaggttct atcctcaaac tcaaagatgg tttgaagaat gtggtcgaat
    13681 ggggaattgc gaatccgcat gaagcagtca tgatggccag cttcaaccca gctaaatccg
    13741 ttcacatcga tgacgtctgt ggccaaatcc gtgaaggcta cgacgctgac ttcatcgtat
    13801 tagataaaga tttggaattg gtagcaacct acctagatgg tgtgaaacgt tatcaagcat
    13861 aagagagaag gcagaagtta gagactagct tctgcttttt tatacagggt actttactgg
    13921 taaataaaaa gttaaaaaaa tcacaaaaaa agcttgaaga aacaaagaaa aaggcttaca
    13981 attgaactat aaatattaca aataaaaaaa cggaggagtg ctttatgaaa gcctatactt
    14041 atgttaaacc aggacttgct tcttttgttg atgtagacaa accagttatt cgcaagccaa
    14101 cagacgctat tgtgcgtatt gtaaaaacca ctatttgtgg aacagacctc catattatca
    14161 aaggggatgt tcctacttgc caaagtggta ccattcttgg ccacgaaggg attgggattg
    14221 ttgaagaagt tggggaagga gtttccaact tcaaaaaagg cgacaaggtc ttgatttctt
    14281 gcgtctgtgc ctgtggtaaa tgctactact gtaaaaaagg aatttatgcc cactgtgaag
    14341 acgaaggggg ctggattttc ggtcacttga ttgatggtat gcaggctgaa tatctacgtg
    14401 tccctcatgc agataatact ctttaccata ctccagaaga cttgtcagat gaagctttgg
    14461 ttatgctgtc agacattctg cctactggat atgaaattgg tgtcttaaaa gggaaagtag
    14521 aacctggttg cagcgtagcc attattggtt caggtccagt tggattggct gctcttttaa
    14581 cagcccaatt ctattcacca gctaaattga ttatggtaga cctagacgat aaccgcttgg
    14641 aaactgccct atcattcggt gcgactcata aggttaattc ttcagaccct aaaaaagcca
    14701 ttaaagaaat ttatgatttg acagatggtc gtggtgtgga tgtcgctatc gaagctgtag
    14761 ggattcctga aacatttgat ttctgtcaaa agattatcgg tgtagacgga acggttgcca
    14821 actgtggtgt gcatggtaaa ccagttgaat tcgatttaga taaactttgg attcgcaaca
    14881 tcaatgtaac aactggtttg gtatctacaa atacgactcc acaattgttg aaagcacttg
    14941 aaagtcataa gattgaaccg gaaaaattgg taactcacta tttcaaactc agtgaaattg
    15001 aaaaagccta cgaagtcttc agtaaggcag cagaccacca tgccattaag gtcattatcg
    15061 aaaacgatat ctcagaagcc taagtagtaa aaatattttt gtacataagt aaatagaaat
    15121 tcagtcatcc atcagatggt tggatttttt atcaaaaaat taagaaatga gcatatttct
    15181 ttccttgtct ggcggaattg gttataatat acggtacaaa ggaatgaatg aatatgtatc
    15241 gtgttataga aatgtacgga gattttgaac cgtggtggtt cttagaaggt tgggaagaag
    15301 atattgtagc aagtagaaaa tttgaccagt attatgatgc tctcaaatac tacaaaactt
    15361 gctggtttag attggaacaa gaatcgcctc tttataaaag tagaagcgac ttgatgacca
    15421 ttttttggga cccggaagac caacgctggt gtgatgaatg tgatgagtat ttacaacaat
    15481 accattcttt ggctcttttg caggatgagc aggttatccc agacgaaaaa ctacgctcag
    15541 gctatgaaaa acaaaccagt caggaaagga atcgttcttg ccgtatgaaa ttaaaataga
    15601 gaaaagtaac tttttggagt tgcttttttt atttttctaa cgctttgcga atagtatagg
    15661 tgaggaggta agtatggttc aagaaattgc acaagaaatc attcgttcgg ctcggaaaaa
    15721 aggggcgcaa gacatttatt ttgtccccaa gttagatgcc tatgagcttc atatgagggt
    15781 aggagacgag cgctgtaaaa ttggtagcta tgattttgaa aagtttgcag ccgttatcag
    15841 tcactttaag tttgtggcgg gtatgaatgt gggagaaaaa agacgtagtc aactgggttc
    15901 ctgtgattat gcctatgacc agaagatggc gtctctacgt ttatctactg taggcgatta
    15961 tcgggggcat gagagtttgg ttatccgttt gttgcacgat gaggagcagg acttgcattt
    16021 ttggtttcag gatattgaag aattaggcaa gcagtacagg caacggggac tctatctttt
    16081 tgctggtccg gttgggagtg gtaagacgac cttgatgcat gaattgtcca agtcactctt
    16141 taaaggacag caagttatgt ccatcgaaga tcctgtcgaa atcaagcagg acgacatgct
    16201 tcagttgcag ttgaacgaag caatcggcct aacctatgaa aatctaatca aactttcctt
    16261 gcgtcatcga ccagatctct tgattatcgg agaaattcgt gacagcgaga cggcgcgtgc
    16321 agtggtcaga gctagtttga caggtgcgac agtcttttca accattcacg ccaagagtat
    16381 ccgaggtgtt tatgagcgtc tgctggagtt gggtgtgagt gaagaagaat tggcagttgt
    16441 tctgcaagga gtctgctacc agagattaat cgggggagga ggaatcgttg actttgcaaa
    16501 cagagattat caagaacacc aagcagccaa gtggaatgag caaattgacc agcttcttaa
    16561 agatggacat atcacaagtc ttcaggctga gacggaaaaa attagctaca gctaagcaaa
    16621 aaaatatcat caccctattt aacaatctct tttctagcgg ttttcatctg gtggagacta
    16681 tctccttttt agataggagt tccttgttgg acaagcagtg tgtgacccag atgcgtacag
    16741 gcttgtctca ggggaaatca ttctcagaaa tgatggaaag tttgggatgt tcaagtacca
    16801 ttgtcactca gttatctcta gctgaagttc atggcaatct tcacctgagt ttgggaaaga
    16861 tagaagaata tctagacaat ctggccaagg tcaagaaaaa gttaattgaa gtagcgacct
    16921 atcctttgat tttgctgggt tttcttctct taattatgct ggggctacgg aattacctgc
    16981 tcccacaact ggatagtagc aatattgcca cccgaattat cggtaatctg ccacaaattt
    17041 ttctaggcat ggtagggctt gtttccgtgc ttgccctttt agcactaact ttttataaaa
    17101 gaagttctaa gatgagtgtc ttttctatct tagcacgcct tccctttatt ggaatctttg
    17161 tgcagaccta cttgacagcc tattatgcac gtgaatgggg gaatatgatt tcacagggaa
    17221 tggagctgac gcagattttt caaatgatgc aggaacaagg ttcccagctc tttaaagaaa
    17281 tcggtcaaga tctggctcaa accctgaaaa atggccgtga attttctcag acgataggaa
    17341 cctatccttt ctttaggaag gaattgagtc tcatcataga gtatggggaa gttaagtcca
    17401 agctgggtag tgagttggaa atctatgctg aaaaaacttg ggaagccttt tttacccgag
    17461 tcaaccgcac catgaatttg gtgcagccac tggtttttat ctttgtggca ctgattatcg
    17521 ttttacttta tgcggcaatg ctcatgccca tgtatcaaaa tatggaggta aatttttaaa
    17581 atgaaaaaaa tgatgacatt cttgaaaaaa gctaaggtta aagcttttac attggtggag
    17641 atgttagtag tcttgctgat tatcagcgtg cttttcttgc tctttgtacc taatctgacc
    17701 aagcaaaaag aagcagtcaa tgacaaagga aaagcagctg ttgttaaggt ggtggaaagc
    17761 caggcagaac tttatagctt ggataaaaat gaagatgcta ctctgagcaa gttacaagga
    17821 gatgggcgca tcacggaaga acaggttaaa gcttataatg aatactatac taaaaatgga
    17881 ggggcaaatc gtaaagtcaa tgattaaggc ctttaccatg ctggaaagtc tcttggtttt
    17941 gggacttgtg agtatccttg ccttgggctt atccagctct gtccagtcca cttttgcagc
    18001 agtagaggag cagattttct ttatggagtt tgaagaactc tatcgggaaa cccaaaaacg
    18061 cagtgtagcc agtcagcaaa agactagtct aaatttagat gggcagacgc ttagcaatgg
    18121 cagtcaaaag ttgacagttc ctaaaggaat tcaggcacca tcaggccaaa gtattacatt
    18181 tgaccgagct gggggcaatt cgtccctggc taaggttgaa tttcagacca gtaaaggagc
    18241 gattcgctat caattatatc taggaaatgg aaaaattaaa cgcattaagg aaacaaaaaa
    18301 ttagggcagt gattttactg gaagcagtag tcgctctagc tatctttgcc agcattgcga
    18361 ccctcctttt gggacaaatt caaaaaaata ggcaagagga agcaaaaatc ttgcaaaagg
    18421 aagaagtctt gagggtagct aagatggccc tgcagacggg gcaaaatcag gtaagcatca
    18481 acggagttga gattcaggta ttttctagtg aaaaaggatt ggaggtctac catggttcag
    18541 aacagttgtt ggcaatcaaa gagccataag gtcaaggctt ttaccttgtt agaatccctg
    18601 cttgccctca ttgtcatcag tgggggatta ctcctttttc aaactatgag tcagctcctc
    18661 atttcagaag ttcgctacca gcaacaaagc gagcaaaagg agtggctctt gtttgtggac
    18721 caacttgagg cagaattaga ccgttcgcag ttcgaaaaag tagaaggcaa tcgcctatac
    18781 atgaagcaag atggcaagga catcgccatc ggtaagtcaa agtcagacga ttttcgtaaa
    18841 accgatgcta gtggacgggg gtatcagcct atggtttatg gcctcaaatc agctcagatt
    18901 acagaggaca atcaactggt tcattttcgt ttccagtttc aaaaaggctt agaaagggag
    18961 ttcatctatc gtgtggaaaa agaagaaagt taaggcaggt gttctcctct acgcagtcac
    19021 catagcagcc atctttagtc ttttgttgca attttatttg aaccgacaaa tcgcccacta
    19081 tcaagactat gctttaaata aagaaaaatt ggttgctttt gccatggcta aacgaaccaa
    19141 ggataaagcc gagcaagaaa gtggggaaca ggtttttaat ctaggtcagg taagctatca
    19201 aaacaagaaa acaagcttgg tgacgactgt tcgtacgtct aagagccaat atgagtttct
    19261 gtttccttca gtcaaaatca aagaagagaa aagagataaa aaggaagagg tagcgaccga
    19321 ttcaagcgaa aaagcggaga aaaaaaatca gaagagaagc ctgaaaagaa agagaattcc
    19381 tagtcaattc aactataatg cgttgaatcc agaatagtcc actgtagttt ctagaaaatt
    19441 gctggaaatg gatgttaagc tccaattcat ttgtttatat cttatttcag tttactatac
    19501 tttgtgctaa attaaagata tgaaacatga ttttaaccac aaagcagaaa ctttcgattc
    19561 ccctaaaaat atcttcctcg caaacttggt atgtcaagca gccgagaaac agattgatct
    19621 tctatcagac aaagaaattt tagatttcgg tggtgacacg ggtctattag ccttgcccct
    19681 agcccctagc caagcaggct aagtcagtca ctcttgtaga catttctgag aaaatgttgg
    19741 agcaagctcg tttgaaagtg gagcagcaag caatcaagaa tatccagttt ttggagcaag
    19801 atttaccgaa aaatcccttg gagaaagagt ttgatttcct tgctgttagt cgggttcttc
    19861 atcatatgcc tgatttggat gcggctctct cactgtttca tcaacatttg aaggaagatg
    19921 ggaaactcat cattgctgat tttaccaaga cagaagctaa tcatcatgga tttgatttag
    19981 ctgaactgga aaacaagcta attgagcatg gtttttcatc tgtgcatagt cagattctct
    20041 atagcgctga agacctgttt caaggaaatc actcagaatt ctttttaaca gtagcccaaa
    20101 aatcactcgc ctagtcaggg agtgattttt ctataaggat ggaaaaaaga agggaaattt
    20161 gataagatag gaatatggat tttgaaaaaa ttgaacaagc ttatatctat ttactagaga
    20221 atgtccaagt catccaaagt gatttggcga ccaactttta tgacgccttg gtggagcaaa
    20281 atagcatcta tctggatggt gaaactgagc taaaccaggt caaagacaac aatcaggccc
    20341 ttaagcgttt agcactacgc aaagaagaat ggctcaagac ctaccagttt ctcttgatga
    20401 aggctgggca aacagaaccc ttgcaggcca atcaccagtt tacgccagat gctattgcct
    20461 tacttttggt atttattgtg gaagagttgt ttacagagga ggaaattact atcctcgaaa
    20521 tgggttctgg gataggaatt ctaggcgcta ctttcttgac ctcgcttgat aaaaaggtgg
    20581 attacttggg aatggaagtg gatgatttgc tgattgatct ggcagctagc atggcagatg
    20641 taattggttt gcaggctggc tttgtccaag gagatgccgt tcgtccacaa atgctcaaag
    20701 aaagcgatgt ggtcatcagt gacttgcctg ttggctatta tcctgatgat gccgttgcgt
    20761 cgcgccatca agttgcttct agccaagaac atacttacgc ccatcacttg ctcatggaac
    20821 aaggacttaa gtacctcaag tcagacggat acgctatttt tctagctccg agtgatttgt
    20881 tgaccagtcc tcaaagtgat ttgttgaaag tctggttgaa agaggaggca agtctggttg
    20941 ctatgattag tttacctgaa aatctctttg ctaatgctaa acaatctaag actattttta
    21001 tcctacagaa gaaaagtgaa atagcagtgg agccttttgt ttatccactt gctagcttgc
    21061 aagatgcaag tgttttaatg aaatttaaag aaaattttca aaaatggact caaggtactg
    21121 aaatataaaa tagattttgt tataatagtt gaaaacgctt aaaaaggggt atcatgttat
    21181 gacaaaaaca attgcaatca atgcaggaag ttcaagtttg aaatggcaat tatacttaat
    21241 gccagaagaa aaagtattgg cgaaaggttt gattgaacgt atcggtttga aagattcaat
    21301 ttcaactgta aaatttgacg gccgttctga acaacaaatt ttggatattg aaaatcatac
    21361 acaagccgtt aaaattttat tggatgactt gattcgtttc gatattatca aggcttatga
    21421 cgagattaca ggtgttggac atcgtgttgt tgctggtgga gaatatttca aagaatcaac
    21481 agttgttgag ggagatgttt tagaaaaagt tgaagagttg agtttgttgg ctcctctaca
    21541 caacccggcc aatgcagcag gtgttcgtgc cttcaaggaa ttgttgccag acattaccag
    21601 tgtagttgtt tttgatactt ccttccacac aagtatgcca gagaaagctt atcgctaccc
    21661 tctaccaaca aaatattaca cagaaaacaa ggttcgtaaa tacggtgctc atggtacaag
    21721 tcaccagttt gtagcaggag aagctgcaaa actcttggga cgtccattag aagacttgaa
    21781 gttaattacc tgtcatattg gtaacggagg ctcaattaca gctgtgaaag ccggcaaatc
    21841 tgtagacact tctatggggt tcactcctct tggtggtatt atgatgggaa cgcgtacagg
    21901 ggatattgat ccagctatca ttccttattt aatgcaatat acagaggatt ttaacacacc
    21961 agaagatatc agtcgtgttc ttaaccgtga atcaggtctt ttgggagttt ctgctaattc
    22021 tagcgatatg cgcgatatag aagcagctgt agcagaaggg aatcacgagg ctagcttggc
    22081 ttatgaaatg tatgttgacc gtatccgaaa acatatcggt cagtaccttg cagtgttaaa
    22141 tggagcagat gccattgttt tcacagcagg tgtcggtgaa aatgcagaga gtttccgtcg
    22201 tgatgtaatc tcagggattt cgtggtttgg ttgtgatgtt gatgatgaaa agaatgtctt
    22261 tggcgttaca ggagacatct caacagaggc agctaaaatc cgtgtcttgg ttattccaac
    22321 agatgaagaa ttagtcattg cccgtgacgt tgaacgcttg aaaaaataag tgaaactaaa
    22381 aaaatattca atacaaggag ttgggaaagt tatttttcca gcttcttttt ctgatgaaat
    22441 tgtccaaaac cttgctatga ttggcttttt tgaaaaatat ggtataatag tagtaattta
    22501 atagatggag ttgagttttg aagaaaaact ttcgtgtaaa aagagagaaa gattttaagg
    22561 cgattttcaa ggaggggaca agttttgcta atcgcaaatt tgtggtctac caattagaaa
    22621 accagaaaaa ccattttcga gtaggtctat cagttagcaa aaaactgggg aatgccgtca
    22681 ctagaaatca aattaagcga cggattcggc atattatcca gaatgcaaaa gggagtctgg
    22741 tagaagatgt cgactttgtt gtcattgctc gaaaaggagt cgaaaccttg ggatacgtag
    22801 agatggagaa aaatctactc catgtattaa aattatcaaa gatttaccgg gaaggaaatg
    22861 ggagtgaaaa agaaactaac gttgactagt ttgctaggac tgtctctgtt aatcatgaca
    22921 gcctgtgcga ctaatggggt aactagcgat attacagccg aatcggctga tttttggagt
    22981 aaattggttt acttctttgc ggaaatcatt cgctttttat cgtttgatat tagtatcgga
    23041 gtggggatta ttctctttac ggtcttgatt cgtacagtcc tcttgccagt ctttcaggtg
    23101 caaatggtgg cttctaggaa aatgcaggaa gctcagccac gcattaaggc gcttcgagaa
    23161 caatatccag gtcgagatat ggaaagcaga accaaactag agcaggaaat gcgtaaagta
    23221 tttaaagaaa tgggtgtcag acagtcagac tctctttggc cgattttgat tcagatgccg
    23281 gttattttgg ccctgttcca agccctatca agagttgact ttttaaagac aggtcatttc
    23341 ttatggatta accttggtag tgtggataca acccttgttc ttccgatttt agcagcagta
    23401 ttcacctttt taagtacttg gttgtccaac aaagctttgt ctgagcgaaa tggcgctacg
    23461 actgcgatga tgtatgggat tccagtcttg atttttatct ttgcagttta tgcgccaggt
    23521 ggagtcgccc tatactggac agtgtctaat gcttatcaag tcttgcaaac ctatttcttg
    23581 aataatccat tcaagattat cgcagagcgc gaggccgtag tacaggcaca aaaagatttg
    23641 gaaaatagaa aaagaaaagc caagaaaaag gctcagaaaa cgaaataaat aaggaggaat
    23701 ctggtaatgg tagtatttac aggttcaact gttgaagaag caatccagaa aggattgaaa
    23761 gaattagata ttccaagaat gaaggctcat atcaaagtca tttctaggga gaaaaaaggc
    23821 tttcttggtc tatttggtaa aaaaccagcc caagtggata ttgaagcgat tagtgaaacg
    23881 actgttgtca aagcaaatca acaggtagta aaaggcgttc cgaaaaaaat caatgatttg
    23941 aacgagcctg tgaagacggt tagtgaagaa accgttaacc ttggtcatgt ggttaatgct
    24001 attaaaaaaa tagaggaaga aggtcaaggt atttctgatg aagtcaaggc tgaaatctta
    24061 aaacatgaaa gacatgccag cactatctta gaagaaactg gtcacattga gattttaaat
    24121 gaacttcaaa tcgaggaagc gatgagggaa gaagcaggcg ctgatgacct tgaaactgag
    24181 caagatcaaa ctgaaaatca agacttgaaa gagatgggct tgaaggtcga gcaaagttat
    24241 gatattgccc aggtggctac ggatgtgact gcctatgttc aagcaattgt ggatgacatg
    24301 gatgttgaag ctacactttc aaatgattat aaccgtcgta gcatcaatct acaaattgac
    24361 accaacgaac caggtcgtat tatcggctac catggtaaag tcttgaaggc cttgcaactg
    24421 ttggctcaaa attatcttta caaccgctat tccaaaacct tctacgttac aatcaatgtc
    24481 aatgattatg tcgaacaccg tgcagaagtc ttgcagacct atgcacaaaa attggcgaat
    24541 cgtgttttgg aagaaggtcg cagtcataaa acagatccaa tgtcaaatag cgaacgcaag
    24601 attatccatc gtattatttc acgtatggat ggcgtgacta gttactctga aggtgatgag
    24661 ccaaatcgct atgttgttgt agatacagaa taagtaaaat caggtttatc ctgatttttt
    24721 gctagttaga ggaggttaaa ctgatgttga ataagataag agactattta gactttgctg
    24781 gtttgcagta ccgtaatcct gataaagcgg gagcagagcg agagaagatg ctggcattcc
    24841 gccacaaagg acaagaggct cgaaaggctt ttacagaact ggccaaagcc tttcaagcaa
    24901 gccatccaga atggcaactc caacagacta gtcagtggat gaatcaggcc cagcgtttga
    24961 gaccacattt ttgggtttat ctacagagag acggacaagt gacagaacct atgatggcct
    25021 tacgtttgta tgggacatct actgactttg gaatttcttt ggaagtcagt ttcatcgaac
    25081 gtaagaagga tgagcaaact ttagagaaac aggccaagat tttagacatt ccaaccgtta
    25141 aaggaattta ttatctagcc tactctgatg gccaaagtca acggtgggag gcgaacgaag
    25201 aaaagcgtcg tactttacgc gagaaggtga gaagtcaaga agttcgaaaa gttttagtga
    25261 aggtagatgt tcctatgaca gaaaattcgt ctgaagaaga aatcgtagaa ggcttattga
    25321 agtcttattc taaaattctt ccctattatc tagctacgag aaaataagat aatttgtaaa
    25381 acatcataaa tcatacagtc caagagtgaa cagtccgctg tgtaattctt ggtctttttg
    25441 tttgcgcttt cgcattatat aataaactta caaaaacaat tcaaaaggag aacaattatg
    25501 gaagtcgttt caaatgttct aaattggttt tctagcaata ttttgcagaa tcccgcattt
    25561 ttcgtaggtt tattggtgtt gataggatat gcacttttga aaaaacctgc ccatgacgtt
    25621 ttttcagggt ttgttaaagc aacagtaggg tatatgttgc ttaacgtggg tgctggtggt
    25681 ttggttacaa cctttcgtcc aatcttagca gctcttaact acaaattcca aattggtgca
    25741 gcggttatcg acccttactt tggacttgct gcagcaaaca acaaaattgc agcagagttt
    25801 ccagattttg ttggaactgc aactacagct ctattgattg gttttggaat aaatatcttg
    25861 ctcgtagctc ttcgaaagat tacgaaggta agaaccctct ttattactgg tcacatcatg
    25921 gtacaacaag ctgcaacagt atctcttatg gttctattct tagtaccaca attgcgcaat
    25981 gcttacggta cagcagcgat tggtatcatc tgtggacttt actgggcagt tagttcaaat
    26041 atgactgttg aggcaactca acgcttgact ggtggtggcg gatttgcgat tggtcaccaa
    26101 cagcaatttg caatctggtt tgtagataaa gtagcaggac gctttggtaa gaaagaagaa
    26161 agtttagaca atcttaaatt acctaagttc ctctcaatct tccacgatac agttgttgca
    26221 tctgctacct tgatgctcgt attcttcgga gccattcttt taatcttggg tccagacatt
    26281 atgtctaata aagaagtcat cacttcagga actctattca atcctgctaa acaagatttc
    26341 tttatgtaca ttatccaaac agcctttacc ttctcagttt acttgttcgt tttgatgcaa
    26401 ggtgtccgaa tgttcgtatc tgagttgaca aacgccttcc aaggtatttc aaacaaattg
    26461 ttgccaggtt cattcccagc ggttgacgtt gcagcttctt atggatttgg ttctccaaat
    26521 gctgtcttgt caggatttac ctttggtttg attggtcaat tgattacaat tgtcttgctc
    26581 atcgtcttta aaaatccgat tcttattatt acaggatttg taccagtgtt ctttgacaat
    26641 gcagccattg cggtctacgc tgataaacgc ggcggatgga aagcggctgt tatcctttcc
    26701 tttatatcag gtgtccttca agttgctcta ggagctcttt gtgtggccct tctcgatttg
    26761 gcatcttatg gtggctacca tggaaatatc gactttgaat tcccatggct tggatttgga
    26821 tatatcttca aataccttgg tattgttggt tatgtacttg tgtgtctctt cttgcttgtt
    26881 attcctcaac ttcaatttgc caaagcaaaa gataaagaga aatattacaa cggtgaagtt
    26941 caagaagaag cttagtatct agaaaaggag aaataaaatg gttaaagtat tagcagcgtg
    27001 cggaaatgga atgggttcat caatggttat caagatgaag gttgaaaatg ctctccgtaa
    27061 gcttaatcaa acagatttta cagtcaattc atgcagtgtc ggtgaagcta aaggtttagc
    27121 agtaggatat gacatcgtaa tcgcttctct tcatttgatt caagaattgg aagggcgaac
    27181 taatgggaag ttaattgggc ttgataactt gatggatgat aaagaaatca ccgaaaaact
    27241 cagtcaagca ctacagtaaa aggttggagg gggctggaca gaaactgaga gttatcgttt
    27301 ctgtccttct ccctctttaa ataaaggagg cagatatgaa tttaaaacaa gctttaattg
    27361 acaatgactc gatccgacta ggtttagagg ctaacaattg gaaagaagca gtcaaggtag
    27421 cagtagatcc cttaattgaa agtggggcaa ttttgccaga gtattacgat gctatcattg
    27481 aatcgactga agagtatggg ccttactata tcttgatgcc aggtatggct atgccccacg
    27541 ctagacctga agctggtgtg caaagtgatg ccttttcatt gattacctta caaaatcctg
    27601 ttgtattttc agatgggaaa gaggtatctg ttttgttggc actagcagca acaagctcaa
    27661 aaattcacac aagtgtagcc attccacaaa ttattgccct gtttgaatta gacgattcta
    27721 ttgcacgttt acaggcttgc cagactaaag aagatgtctt ggctatgatt gaagaatcta
    27781 aggatagccc ttatctcgaa ggattggatt tggaaagtta gaaagaggaa taaagaaatg
    27841 acaaaaaaaa tacctaattt acaagttgca ttagaccatt cagacttgca aggagcgatt
    27901 aaagcagctg tttctgttag tcaggaagta gatattatcg aagctggaac tgtttgcttg
    27961 cttcaagttg gaagtgaact ggctgaagtc ttgcgtagcc ttttcccaga taagattatt
    28021 gtggcagaca caaaatgtgc tgatgctggt ggaacagttg ctaaaaataa tgcggttcgt
    28081 ggagcagact ggatgacttg tatctgttgt gcaaccatcc ctactatgga agcagctcta
    28141 aaggctatca agactgaacg aggagaacga ggcgaaatcc agatcgagct ttatggcgat
    28201 tggacttttg aacaagctca gctttggcta gatgcaggta tctcacaagc tatttatcac
    28261 caatctcgtg atgctcttct tgctggtgaa acttggggtg aaaaagacct taataaggtt
    28321 aaaaaactca ttgacatggg cttccgtgta tctgtaacag gtggtctaga tgtagatact
    28381 ctcaaactct ttgaaggtgt tgatgtcttt acctttatcg caggtcgtgg aattacagag
    28441 gctgcggatc cagcaggagc agcgcgtgcc ttcaaggatg aaatcaaacg aatttggggg
    28501 taaatcatgg tacgtccaat tggaatttat gaaaaggcaa ccccaacaca ctttacttgg
    28561 ctagaacgtt taaattttgc caaggagtta ggctttgatt ttgtcgaact gtctattgac
    28621 gaacgtgacg agcgtttagc aagacttgac tggagtaagg aagaacgctt ggaagttgtc
    28681 aaagcaatct atgaaactgg tgttcgtatt ccttctatct gtttttcagg ccatcgtcgc
    28741 tacccattgg gttcaaaaga tccagttcta gaggaaaaat ctctagaact catgaaaaaa
    28801 tgtatcgaat tagctcaaga cttgggagtt cgtacgattc aattagctgg ttacgatgtt
    28861 tactatgagg aaaagtcacc ccagacacgc caacgtttta tcaaaaattt gagaaaagcc
    28921 tgtgactggg ctgaagaagc tcaggtggta cttgctattg aaattatgga tgatcctttc
    28981 atcagtagca tcgaaaaata tttggttata gaaaaagaga ttgactctcc cttcctcttt
    29041 gtatatccag atattggtaa tgtgtctgca tggcataatg atatctatag tgagttttat
    29101 cttggtcatc atgccatcgc agctctccat ctcaaggata cttatgcagt gacagaaagt
    29161 tcaaagggcc agttccgaga tgtacctttc gggcaaggtt gtgtcaaatg ggaagaagct
    29221 ttcgatattt taaaggaaac caattataat ggacctttcc taatcgaaat gtggtctgaa
    29281 aattgtgaaa cagtagaaga aacacgcgca gccattcaag aggcgcaagc ttttctctat
    29341 ccactcatta agaaagcagg tttgatgtaa gatgaatcaa gtaatcaatg ctatgcgtaa
    29401 acgagtatgt gatgccaatc aatcattgcc aaaacatgga cttgtcaaat ttacctgggg
    29461 gaatgtatct gaagtcaatc gcgaactcgg tgtcattgtt atcaaaccat caggcgtgga
    29521 ttatgacgaa ttgacacctg aaaacatggt agtgactgat ctagatggta agatcctaga
    29581 aggggattta agaccatctt ccgacctccc aactcatgtg caattatata aggcttggtc
    29641 agaaattggt agtgtggttc acacccattc gacagaagct gttggttggg ctcaggcagg
    29701 tcgtgatatt cctttctacg gaacaaccca tgcagattat ttctacggtt caatcccttg
    29761 cgcccgtagt ttgaccaagg acgaagtaga agtgacctat gaaaaagata ctggcctggt
    29821 tatcgtagaa gagtttgaac atcgcggact taacccggtt gaagtaccag gaattgttgt
    29881 acgcaatcac ggtccattca cctggggcaa aaatccagag aatgctgttt atcactctgt
    29941 cgtactagag gaagtatcaa agatgaatcg ctttacagaa caaatcaatc taagagttgg
    30001 acctgctccc cagtacatac tagaaaaaca ctaccaacgt aaacatggac caaatgctta
    30061 ttatggtcaa aagtaagaac gatgaaggag gagaaaaaga taaatttagc tcctcttttt
    30121 acatttgatt tttattgaga gtaaagttgg agttgaagta attttaaaag attttttaga
    30181 aatagcgctt gatatatata tggtaaaata aaaagaattg ctgtgatatc aatagatttg
    30241 ggggattttt taatatggta ctggataagg caagttgtga tttgcttcaa tatttgatgg
    30301 atcaagaaac gtccaaaacg attatggcga tttcgaaaga tttgaaagag tcaagaagga
    30361 aaatttatta tcacattgac aaaatcaatg ctgctctggg tgacgaggcg cttcacatca
    30421 ttagtattcc acgaattggt attcacttaa cggaagagca gagagatgct tgttgtaaac
    30481 tattatcgga agtagattcg tacgattata tcatgagtgc gcatgaacgt atgatgataa
    30541 tgttactatg gataggtatt tctaaagaac gtattacgat tgaaaaattg atagagttaa
    30601 cagaggtatc taggaatact gttctcaatg atttgaatag tattcgttat caactaactt
    30661 tggaacaata tcaggtgatc ttgcaagtga gcaagtcaca gggataccac cttcatgccc
    30721 accctcttaa taaaattcag tatcttcaat cgcttctata tcatattttt atggaagaaa
    30781 atgccacttt tgtatctatt ttagaagata agatgaaaga gaggttagat gatgagtgtt
    30841 tgctttctgt tgaaatgaac caatttttta aggaacaggt tcctttagtt gaacaagatt
    30901 tagggaagaa aataaatcat catgaaataa cttttatgtt gcaggttcta ccttatttgc
    30961 tgttaagctg tcataatgtt gaacagtatc aagaaagaca tcaggatata gagaaagagt
    31021 tttctttgat aagaaaaaga atagagtatc aggtgtctaa gaaattagga gaacggttgt
    31081 ttcaaaagtt tgaaatttct ttgtcaggac ttgaagtttc tcttgtagct gttctcctcc
    31141 tctcctatcg taaagatttg gatattcatg cagaaagtga tgattttcgg caattaaaac
    31201 ttgctttaga agaatttatc tggtattttg aatcacaaat ccgaatggag attgagaaca
    31261 aggatgattt gttacgaaat ttgatgatcc actgtaaagc cttgttattt agaaagactt
    31321 acggtatttt ttctaaaaat cctctaacaa aacaaattcg atccaagtat ggagaattat
    31381 ttttagtcac tagaaaatct gcggaaattt tagaaggagc atggtttatt cggctaacag
    31441 acgatgatat tgcctatttg acgattcata ttggaggatt tttaaaatat acaccatcgt
    31501 ctcaaaaaaa tatgaaaaaa gtttatctcg tttgtgatga aggtgttgcg gtttcgagac
    31561 ttttgctgaa acaatgcaaa ctttattttc caaatgagca aattgacact gtatttacaa
    31621 cagaacaatt taagagtgtg gaagatattg cacaagttga tgtagtgatt actactaatg
    31681 atgatttgga tagcagattt ccgattttaa gggttaatcc tatccttgaa gcagaagata
    31741 ttttgaaaat gctagactat cttaaacaca atatatttcg taataagagc aaaagtttca
    31801 gtgaaaatct ttctagtctt atttcgtctt atattgtaga cagcaagttg gctagtaagt
    31861 tccaagaaga ggttcaaaca cttataaatc aagaaatagt agttcaagct tttttggaag
    31921 atatttgaag gacagtccaa tgatgaacac aaacctgtgt ttttcttggt cttttttagt
    31981 gttttgaagg gtggtatact aatctcaaag ataacaatta tatccaaagg aggcaacata
    32041 tgccaaacgt caaagaaatt acaagagagt catggatttt agccactttc ccagagtggg
    32101 gaacatggtt gaacgaagaa atcgaagaag aagtcgtacc tgaaggcaac tttgccatgt
    32161 ggtggctagg caactgtggt acttggatta agacaccagc tggtgctaac gttgtcatgg
    32221 acctttggtc aaaccgtgga aaatcaacca aaaaagtgaa agatatggtt cgtgggcacc
    32281 aaatggcaaa tatggcaggt gttcgtaagt tgcaaccaaa cttgcgtgtt cagccaatgg
    32341 ttatcgatcc atttgctatc aacgaactag actattactt agtttcacac ttccacagtg
    32401 atcatatcga cccatacaca gctgcagcaa ttctcaacaa tcctaagtta gagcatgtta
    32461 agtttatcgg tccttaccac tgtggacgaa tctgggaagg atggggtgtt ccaaaagaac
    32521 gtatcatcgt tgttaaacca ggtgacacta tcgaattaaa agatatgaag attcatgcag
    32581 tagaatcatt tgaccgtact tgcttggtaa ctctcccagt gaacggtgct gatgagacag
    32641 gcggtgaact tgctggcttg gctgttacag atgaagaaat ggctcaaaag gctgttaact
    32701 atatctttga aacaccaggt ggaaccatct atcatggtgc agattctcac ttctcaaact
    32761 attttgcaaa acatggtaaa gactttaaaa ttgatgttgc tttgaataac tatggtgaaa
    32821 atccggtagg tatccaagac aaaatgacat ctatcgacct tcttcgtatg gcagaaaatc
    32881 tgcgtaccaa agtcattatc ccagttcact atgatatctg gtctaacttc atggcttcta
    32941 ctaatgagat tctagaactt tggaaaatgc gaaaagatcg cttgcaatac gatttccatc
    33001 catttatctg ggaagttggc ggtaagtaca cttatcctca agatcaacac ttagtagaat
    33061 accatcatcc acgtggtttt gatgattgtt ttgaacaaga ctctaacatt caatttaaag
    33121 ctttgctata atataaaaat attttttgga ggttatccgt atgttgcatg atacggataa
    33181 ttttcatata atagtaaaat agaatgtgtg attcaataat cacctcaaat agaaaggaaa
    33241 ttctatgtca aatctatctg ttaatgcaat tcgttttcta ggtattgacg ccattaataa
    33301 agccaactca ggtcatccag gtgtggttat gggagcggct ccgatggctt acagcctctt
    33361 tacaaaacaa cttcatatca atccagctca accaaactgg attaaccgcg accgctttat
    33421 tctttcagca ggtcatggtt caatgctcct ttatgctctt cttcaccttt ctggttttga
    33481 agatgtcagc atggatgaga ttaagagctt ccgtcaatgg ggttcaaaaa caccaggtca
    33541 cccagaattt ggtcatacgg cagggattga tgctacgaca ggtcctctag ggcaagggat
    33601 ttcaactgct actggttttg cccaagcaga acgtttcttg gcagccaaat ataaccgtga
    33661 aggctacaat atctttgacc actatactta cgttatctgt ggagacggag acttgatgga
    33721 aggtgtctca agcgaggcag cttcatacgc aggcttgcaa aaacttgata agttggttgt
    33781 tctttatgat tcaaatgata tcaacttgga tggtgagaca aaggattcct ttacagaaag
    33841 tgttcgtgac cgttacaatg cctacggttg gcatactgcc ttggttgaaa atggaacaga
    33901 cttggaagcc atccatgctg ctatcgaaac agcaaaagct tcaggcaagc catctttgat
    33961 tgaagtgaag acggttattg gatacggttc tccaaacaaa caaggaacta atgctgtaca
    34021 cggcgcccct cttggagcag atgaaactgc atcaactcgt caagccctcg gttgggacta
    34081 cgaaccattt gaaattccag aacaagtata tactgatttc aaagaacatg ttgcagaccg
    34141 tggcgcatca gcttatcaag cttggactaa attagttgca gattataaag aagctcatcc
    34201 agaactggct gcagaagtag aagccatcat cgacggacgt gatccagtcg aagtgactcc
    34261 agcagacttc ccagctttag aaaatggttt ttctcaagca actcgtaatt caagtcaaga
    34321 tgccttgaat gttgtggcag ctaaattacc aacctttcta ggtggatcag ctgaccttgc
    34381 tcactcaaac atgacttata tcaagacgga tggacttcaa gacgatgcca atcgcttgaa
    34441 tcgtaacatt cagtttggtg ttcgtgaatt tgcaatggga acaatcttga acgggatggc
    34501 ccttcatggt ggacttcgtg tatacggtgg aactttcttc gtcttctctg actatgtgaa
    34561 ggcagctgtc cgcttgtcag ccttacaagg acttcctgtg acttatgtct ttacccatga
    34621 ttcaatcgca gttggggaag atggtccgac tcatgaacca gttgagcatt tagcaggtct
    34681 tcgtgctatg ccaaatctaa atgttttccg tccagcagat gcgcgtgaaa cgcaagcagc
    34741 ttggtacctt gcagtgacaa gtgagaaaac accaactgcc cttgtcttga cacgtcaaaa
    34801 cttgactgtt gaagatggaa cagacttcga caaggttgct aaaggtgctt atgttgtata
    34861 tgaaaatgca gccgactttg ataccatctt gattgcgaca ggttcagagg ttaatcttgc
    34921 tgtctcagct gctaaagaat tggctagtca aggcgaaaac atccgcgtag tcagcatgcc
    34981 atctacagat gtctttgata aacaagatgc agcttacaag gaagaaattc ttccaaatgc
    35041 agtccgccgt cgtgttgcag tcgaaatggg tgcaagtcaa aactggtaca aatatgttgg
    35101 tctcgatggt gccgttctag gtattgatac cttcggagcc tctgccccag caccaaaagt
    35161 attggcagaa tatggcttta ctgtagaaaa tcttgtaaaa attgttcgaa acttgaaata
    35221 atcctaaaaa tcagggcgta agctctggtt tttcttacca gaaaagtaag gtacaatctt
    35281 gtaaaagtag ctgaaatttg gtatagtagt cctatgtaaa agacaaagga gaagacaatg
    35341 aatccaaata ttactttttt aatcatgctt gtaggtatga tggccttgat gttctttatg
    35401 caacgttctc aaaagaaaca agctcaaaag cgtatggaaa gcttaaataa actacaaaaa
    35461 ggctatgaag tgattacaat cggtggactt tatggaacag tcgatgaagt agatacggag
    35521 aagggaacaa tagttcttga cgtagatgga gtttacttga cttttgaact agctgctatc
    35581 aagacagtat taccgctgaa agaaacagct tcactagaag gcgcaattga aaaataagac
    35641 gggatcacga actcccgttt ttctataaaa gaaaggaaat gggatgaaaa aattagtctt
    35701 tgtctgtctg ggaaatattt gccgtagccc tatggccgag tttgttatga aatcaatgac
    35761 agataactac gaaatccaaa gtcgagcaac ttcctcttgg gaacatggca atccgattca
    35821 taaggggact cagggaattt ttcaagagta tgagattcct tatgacaaga acaagacatc
    35881 gcttcagatt agtaaggaag attttgaagc ctttgattat attatcggaa tggacgcttc
    35941 aaatatttct gacttacgtc agatgtgtcc agtagactgt caagataaga tttactcatt
    36001 ttcatctgaa agtgttccag acccttggta tacaggagat tttgaagaaa cctatcgacg
    36061 tgttcaagag ggctgtcaag cttggttaga acgtttagaa aaggagagtt aaggtggaaa
    36121 atcttacgaa tttttacgaa aagtatcgtg tctatctgac tcgtccacgt ttagagcttt
    36181 tggcagtagt taccattgtt ttctgtgctg tactcgtctt ttttctaaat attccaggaa
    36241 aaggtgtctt aaaactcgat aatggaacga ttgtttatga tggcagtctt gtccgtggta
    36301 aaatgaatgg tcaaggtacc attaccttcc aaaatggaga ccaatataca ggtggcttca
    36361 acaatggagc cttcaacgga aaaggtacct ttcaatctaa agaaggctgg acctacgaag
    36421 gtgattttgt aaatggtcag gctgaaggaa aagggaaact aacaacagaa caagaagtcg
    36481 tttatgaagg aacttttaaa caaggcgttt ttcaacaaaa ataaagcctc cttatcaaag
    36541 gaggtattat tagaactaca aggtaagcgc ttacctgtaa atccctttct ttccaaatcc
    36601 ctcttccaag caagtttgtg aaataaaaaa catttgaaat aaatttcaca aacttcaaag
    36661 ataaaacctg ataagaaaag aaaatgagaa aagtttcaca agagtttaaa aattctttgt
    36721 gaaatgttta tgaaactgtt tacaaagttg aaataatacg ttataataaa cttgtgaaga
    36781 aattaacaaa ggatatcgat ccttgaaagc tatggaggaa aatatggctg ataaaaaaac
    36841 tgtgacacca gaggaaaaga aactcgttgc tgaaaaacac gtagatgagt tggttcaaaa
    36901 agctctagtt gcccttgaag aaatgcgtaa attggatcaa gagcaagttg actacatcgt
    36961 tgccaaagca tcagtagcag ctttggatgc ccacggagaa ttggctttac atgcctttga
    37021 agaaacagga cgtggtgtat ttgaagataa agcaactaag aacttgtttg cctgtgaaca
    37081 cgtagtaaac aacatgcgcc acactaagac agttggcgtt atcgaagaag acgatgtaac
    37141 cggattgact cttattgctg aaccagttgg tgttgtttgt ggtattactc caacaacaaa
    37201 cccaacatca acagcaatct tcaaatcatt gatttcattg aagacacgta acccaatcgt
    37261 ctttgccttc catccatcag cacaagaatc atctgctcat gcagctcgta tcgtccgcga
    37321 tgcagctatc gcagctggtg ctcctgaaaa ctgtgtgcaa tggattactc aaccatctat
    37381 ggaagcaaca agtgccctta tgaaccacga aggtgttgcg acaatccttg caacaggtgg
    37441 taatgccatg gttaaggcgg cttattcatg tggtaaacca gctcttgggg taggtgccgg
    37501 aaacgttcca gcttatgttg aaaaatcagc aaacattcgt caagcagcac acgatatcgt
    37561 catgtctaaa tcatttgata acggtatggt ctgtgcatct gaacaagcag ttatcattga
    37621 taaagaaatt tacgatgaat ttgtagcaga gttcaaatct taccacactt actttgtaaa
    37681 caaaaaagaa aaagctcttc ttgaagagtt ctgcttcggc gtcaaagcaa acagcaaaaa
    37741 ctgtgctggt gcaaaattga acgctgacat cgttggtaaa ccagcaactt ggattgcaga
    37801 acaagcagga tttacagttc cagaaggaac aaacattctt gctgcagaat gtaaagaagt
    37861 tggcgaaaat gagccattga ctcgtgaaaa attgtcacca gttattgcag ttttgaaatc
    37921 tgaaagccgt gaagatggta ttactaaggc tcgtcaaatg gttgaattta acggtcttgg
    37981 acactcagca gctatccaca cagctgacga agaattgact aaagaatttg gtaaagctgt
    38041 taaagctatt cgtgttatct gtaactcacc ttctactttt ggtggtatcg gggacgttta
    38101 caatgccttc ttgccatcat tgacacttgg atgtggttct tacggacgca actcagttgg
    38161 ggataacgtt agtgccatta acctcttgaa tatcaaaaaa gtcggaagac ggagaaataa
    38221 catgcaatgg atgaaacttc cttcaaaaac atactttgaa cgtgattcaa ttcaatacct
    38281 tcaaaaatgt cgtgacgttg aacgtgtcat gatcgttact gaccatgcca tggtagagct
    38341 tggtttcctt gatcgtatca tcgaacaact ggaccttcgt cgcaataagg ttgtttacca
    38401 aatctttgcg gatgtagaac cggatccaga tatcacaact gtaaaccgtg gtactgagat
    38461 tatgcgtgcc ttcaaaccag ataccatcat cgcactcggt ggtgggtctc caatggatgc
    38521 tgccaaagta atgtggctct tctacgagca accagaagtg gacttccgtg accttgtcca
    38581 aaaattcatg gatatccgta aacgtgcctt caagttccca ttgcttggta agaagactaa
    38641 attcatcgcg attccaacta catctggtac aggatctgaa gtaacaccat ttgccgttat
    38701 ctctgataaa gcaaacaacc gtaaataccc aatcgctgac tactcattga caccaactgt
    38761 ggcaatcgta gatcctgctt tggtattgac agttccagga tttgttgctg ctgatactgg
    38821 tatggacgta ttgactcacg cgacagaagc atacgtatca caaatggcta gtgactacac
    38881 tgatggttta gcacttcaag ctattaaatt ggtctttgaa aatctcgaaa gctcagttaa
    38941 gaatgcagac ttccactcac gtgagaaaat gcataacgct tcaacaatcg ctggtatggc
    39001 ctttgccaat gccttcctag gtatttctca ctcaatggcc cataagattg gtgcgcaatt
    39061 ccacacagtt cacggacgta caaatgccat cttgcttccg tacgttatcc gttacaacgg
    39121 tacacgtcca gctaagacag caacatggcc taagtacaac tactaccgtg cagatgaaaa
    39181 ataccaagat atcgcacgca tgcttggact tccagcttct actccagaag aaggggttga
    39241 atcttacgca aaagctgtct acgaactcgg tgaacgtatt gggatccaaa tgaattttag
    39301 agaccaagga attgacgaaa aagaatggaa agaacattct cgtaaattag ccttcctggc
    39361 ttatgaagac caatgttcac cagctaaccc acgtcttcca atggtagacc atatgcaaga
    39421 aatcatcgaa gatgcatact atggctacaa agaaagacca ggacgccgta aataattgtt
    39481 tatcagtcta gaagcaagac aaaaactcaa tttgagggaa agatccagta atttttctat
    39541 gataaaaggc atcctatcaa ggtttttgaa cacctgatag gatgcctttt tatgatattg
    39601 aggccttttt gccctttttg aaaaactaga atagaaacaa aatatataat agattgaaac
    39661 tagagtagta cacatctgct tctaaaacat tgttagaatt cgatttgact gtcctgatca
    39721 atttgtcttg ttcttatttc attttaatat ataaaaaata tagtatagta gactgaatct
    39781 aaaatagtac gaaacaattg ctaaaacatt tatagaaatt aattttactt ttctgataga
    39841 gttgttcaca tcttatttca attcactata gtttaattta agagtagtat ttactaaggc
    39901 ccaattaaaa tcaaagagca aactagaaaa cgagtgccat tcagctcaaa acactgattt
    39961 gagattgcag ataagactag ccccctcatt aacagattta cgataaaacg atgacaaggt
    40021 gtgttgcttt ttgatttcta aagagtataa tgatagatct ctataaaata agtgcgaagg
    40081 aaatgagctt ttatagtcct ttcgttttaa aatactatct cagatattct tatatcgaca
    40141 agaagttttt gagtcattcc ctcatcatac atattaaata aatagtggct cattcaattt
    40201 ttcactagaa taataagcta gtatagtaaa ctgaaataag atataaacaa ataaattgga
    40261 gcttaacatc catttccagc aattttttag aaactacagt ggactattct agattcaaca
    40321 tattataaaa actagagtaa aagaaaagga ttggatcttg tgtaatgcag gatccaatcc
    40381 tttcaatcat tttgtccaac ttttggaggt tcctacaatg tagtcgttat taataaagac
    40441 agatgggaat gacagtgttc ctatttattt tgatagagat cgatgaattc tttagatagc
    40501 aactgaataa tctctgttga agccatttgg tcttctgcat gcataaatag caaggagaat
    40561 cctatttttt ctccagtagc ttctttttgt atgagattag agtgaatctt gtgcgcttct
    40621 actaaggagt cttccgcttc ttcaacttta attttcgctt cttttaaatt tcctgcctta
    40681 gctagttgga tggcttcaat aaaggatgat ttggctgctc cactattggc aatgagctga
    40741 aaacagatat attccatttc ttctgtcatc ttatttctcc tatccatgca agtgcttgtt
    40801 ccagtacttt tgctccattc atcattccgt aatcccgcat atcaatggta tctacaggga
    40861 tatttcctgc aatttctttc acagcaagta actcataacg aatttgtggc ccaattagaa
    40921 tgacatctgc ttcatggata ttctttttag cttctgtcat tgattttgct tggatagaaa
    40981 tttcaatccc acgttcagtc gcactttgtt gcattttttt aacaagcata cttgtcgaca
    41041 ttcccgcatt acatactaat aaaatttgtt tcataatctt aaccttccat ttcttgctca
    41101 acaactttgt cattaacttt gataaatgga atgtatagaa gaactccaag tgcaaagatg
    41161 atgaattgaa ctagaactgc tctcacgtcc cctgctgttg ctaaccatgc atttaagaat
    41221 actggtgtag tccaaggaac ttgtataaat gcaggactca tgaatcctgt aactgttgct
    41281 aagtagctga ttaaaatacc aaggactgga actgtgataa atggaatagc taatgaaatg
    41341 ttataaacga ttgggtaacc gaataatact ggttcattga tattgaagat accaggtcca
    41401 aaagataatt tagccacgtt tttagagaca gcattgcgac tcactaagaa tgttgctatt
    41461 aataaacata atgtagatcc actaccaccc attaaagcga atgtttgtat ttgtgatagg
    41521 ttgatgatgt gtggaatggc ttgtccatta tttgctgcag tgatgttttc agtaatgtta
    41581 attaatagta atggttctag gatggcactg taaataactg cttggtgaat accaaatagc
    41641 cataacatat ttcctaaaga gtaaataata atgaccccga ttaagcttgt accaatatga
    41701 cgaattggtt cttgaataaa gattgtaatg attgagatta agttcattcc agttatattg
    41761 aataataatg ctgaaacaac cccaaataag gagatgacgg tcatgactgg aagtaatacg
    41821 ctaaatgatc tactaacagc tggtggaata ttttcaccaa ggttcatttg taaagcttta
    41881 acgtttgata attcaatgaa taattctgtt gcaataatcg ctacgataac cccggcgaac
    41941 attgcgcctg tacctgtgtt gttgaatgaa agaacacctg aaatgtttac cgcatctttt
    42001 gctccgtcag gaactacaga aactgtattt ggcatcatca caattaaaga aactaatgat
    42061 agcattgatg ctgctaacgg gttttcgaaa tctctgtttt tagctaagaa ataaccaacc
    42121 attacagcaa taatcatacc tgaaatactt aaagtaccgt ttgcaattgt tattccccaa
    42181 tattggaatt ttgttaatgt atccccttgg aaaatccact taaataccgt gttgttcaaa
    42241 agaacgatta aacctgccaa aatatataat ggcattactg ttacgaatgc atctcttagg
    42301 gtttttaaat gaatttggtt ccctagttta ccagcaaagg tggcaaattg atctataaat
    42361 tttgagcttt tcatctgaat atctcctctc tttactcctc aatttctact tcaaaaccgt
    42421 tattgtcact tactttgcga taccatcttc ctgagctctt gatggttctc ttttgcgttt
    42481 ctaaatcaac ggagataaat ccgtaacgat tcttatatgc attattccaa gaccagcaat
    42541 caaatgcggt ccaagcgtgg tatccaaaac agtgacttcc ctcttcaatg gctttatgta
    42601 gccatcttaa atgttcttca taaaattcaa tacgatacac gtcatcgata actccatttt
    42661 catcgataaa ccgtgcttcg ttttcaacac ccattccgtt ttcactgata aaccatggaa
    42721 tattatcata ttcttccttc acaatcatag caatatcata aatggctttc ggaaaaattt
    42781 cccaaccacg atatggattc atgcgacgct ccggccattc atactctttg aagtattggt
    42841 ctggcatcca gggcgtctga tattcctcag gatttgcttg tgcttgaaca cgttttggat
    42901 ggtagtagtt tactccaaga aaatcaaccg tatttgattt catcagttga agctcttttt
    42961 cggtatgact ccataacacg ccatctctct ctagctgttt taccaatttt tctgggaaag
    43021 ttcctttaac agctggattc aagaagactt tgttaaagaa gtcttctgta aatcgacttg
    43081 cttctaagtc ttctggagaa ttacttcttg gataagcagg tgtcaagttt aaaataatcc
    43141 caatctttcc atcaagttct aatgagcgat atagttgaat cacttttgca ctagcaaggt
    43201 ttagattata gatgacttgt acggcctctt ttccctttcc ttttagattt ggataatgga
    43261 aagcatataa gtatcctgct tctggaatga ccattggctc attgaaagtt gtccagtaat
    43321 gaaccttatc tccaaagcat gtgaaagcag tcttggcaaa cttcacgaat aactccacta
    43381 catgtttgct ttcccaacca ccgtattttt gaagaagttc cactggtaaa tcaaaatgat
    43441 gtaaattcat cacaagatcc atctggttct ttttagcttc ttcaatgatg gcattgtaga
    43501 aagcaatacc ttttggatca ggctcacctg tctctaaatt cttgatgagt cgactccatt
    43561 ggatggaagt gcggaaagaa ttaactccaa tttccttcat caagtggaaa tcttcggtgt
    43621 aagtatgaaa aaagttactg gctacaagag gtccgacatt atcgaaaaaa tcttctggat
    43681 gcgttttgaa ccagtagtcc atcacatttt catgtacttt tccatattga ccttctgtct
    43741 gaggtccgct agaagcagct ccccaccaaa atagattagg aaatactaac ttttttttca
    43801 tgctcaacct cctttctatt attctataca taaagtatag cataatttta aaatttgtct
    43861 agacattttt aaaaattgtt gatacatatc ttgtgtttgc ctcatttctt gaactttgtt
    43921 atactactat tagaatatta tagagagaac cagattaaat gagtacaaaa tatttattta
    43981 tttacaatga gattcgtgaa aagattcttt gtaataaata taccatgaac gaacaattgc
    44041 ctgatgaaat gacattagct aaacagtttg cctgtagtcg aatgacgatc aaaaaagctt
    44101 tagacttgtt agtttctgag ggcttaattt ttagaaaacg tgggcaggga acctttgttc
    44161 tctctcgtgg cagctcaaaa agaaaattaa tcgttccaga aagagatatc cggggactga
    44221 caaaaatatc tgaagatgct cattctacaa ttgactcgag gattattcac ttcaaattag
    44281 aatttgcaaa tgaattttta gcagaaaaac tacaggtcgc tttgcagagt ccagtttata
    44341 atatttaccg tctgcgtatt attgacggta aaccttatgt tctggaacaa acttatatga
    44401 gtactgatgt tattccaggt attactgaag atattttaca aaaatcgatt tacaattaca
    44461 ttgaaggaaa gttaggattg catattgcca gtgctacaaa aatcttgcga gcttcttcta
    44521 gttcagaaaa tgagcaacat tacttgcagc tccttccaac ggaaccggta tttgaagtag
    44581 aacaagtggc ttatttggat aacggaactc cgtttgagta ctcgattagt cgtcatcgct
    44641 atgatttatt tgaatttaat tcttttgcat tacgacattc ctcctaggag aaaatgtgaa
    44701 aatgaagcca atcttttaca gactctagtt taagaaaaat ttaaaacagg gcaagaaggt
    44761 cccatctatg cttaaatggt ttctcttttc taaataagat ggctttaaaa gagtgatcgt
    44821 tttatccatc atgttgaaaa atatcttcgt atagcttata gagtaggtac tgaaattgtt
    44881 cacctgatct acttcttata gttatttagt tttaaatagt gtttcaaata ttcttacact
    44941 gacgagaagt ttttgagtct tttcttgtaa cacatatagt atactgatgt tagaatagta
    45001 gactgtgact tctaacaaat tgctagaaat gaatttcaat ctcccaattt atttgttcat
    45061 atcttctttt aatatattaa ataaattctg aatcataatc atttaaaaaa attttatttt
    45121 ttatttttca ttacgaataa tatagatgaa ggggaaagag tatgaaaaca gaactgtttc
    45181 ttttgctatt agttcaaaag gagaaaaaat gaaagtagaa aatatttcgt atagggtgga
    45241 tcatcgtata ttgtttgata atatttcttt tgatacttcg agttcaggcg tgacattaat
    45301 tactggtaaa aatggtacag gaaagtcaac tttactatag tagattgaaa ctagaatagt
    45361 acacatctac ttctaaaata ttgttagaaa tcgatttgac tatcctgatc tatttgtcct
    45421 gttcttattt catttcacta catctcaaat tgagtatgac gaagtgcgct cccatgtcct
    45481 gggaacgcac tttcttcata tttttcatat tcttgaatcc atcgataaag actattggga
    45541 tgaattttta aagttgaact aattattttt acaggatgag gtttacagca gagagtttga
    45601 aggctttatc aaaggttttt cttggcataa tgacttttcc tcgtttccac ttaattttgt
    45661 gtctacttta ttataccaag tccaccctta agttagataa tgaatctaac ttaaggaagc
    45721 tagaaggatg agaatccagg tggtcaagag tcccaaactt aagctgatag ggacacccag
    45781 aataatttgc tttttgaagg caagaccgcg ttcctctata ttgggaagtg agagttgaat
    45841 gagagaacca gctgatgaaa agggtgagat attagtagat agagcgccaa taacggtggc
    45901 tgttgtgagt aagtgaatat caatctgagg attttgagca ctgatgatag caatgatggg
    45961 aaagagggct ggagctacaa cggatagggt ggaactaaag agtgacatca ctccggctat
    46021 cacacaaaag aacagaggta accagaaatg aggaatggtt gttgtcatga ggtgccctat
    46081 cagtgtgact aaacctgact tgaccgctag agacattagt aagctcatgc cgcagagcat
    46141 gataattgta gcccagggaa ccttagctaa aatggcttct tgcttcccta atttgagcct
    46201 taaggcgagg cagaccatga gtattgagac aaagccaata tcaaatgttt tttgataagt
    46261 agctatccag gcgatgtttg ggaaaatgag atgcaacaag ggaaaaagcc aaaccaaaac
    46321 catgctgctg atcatgagca aggtggtttg tctttgaacc ttgctgagga gtggtggttg
    46381 gtcaatagtc aaggatgagt ttgttcttcc cttactatag tgactgtaac aggataataa
    46441 aagcaagacg atgagtgggt agataatgct gacgataaag atatgattgc caagtgaaaa
    46501 agcttgctct tcccatccca tttgcttaaa caggccttga aagacaatgc ctgagctact
    46561 ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg gcttgagctc caatcaaagg
    46621 gtgtttgtcc gctttttgac agagggtaat cgctagagga cagcaaacgg ccatagtagt
    46681 gaaaaatcca gcacctaaag cagacaaaag ggttgccatc aggtataaaa tcatgtagag
    46741 ggcgttaggg tgggtgcgtg tgcggtagag aatgtgttga gccaaaacat caagagtacc
    46801 gttagttgtt gcaacgttat aaaagagaga gacgctaaaa atggtaaaaa agagtgaggt
    46861 tggccaaaaa tgaagaagtt ctttgggact taatcccatg agagtggttg cgatgaggta
    46921 agaaaaagca atagccagca ggccaatatt gattttggtg cggtaaccaa ttccaatggc
    46981 tagagcaatg gcgctaatca ttattaaatg aatcattgaa ttgtcctttc agttagaata
    47041 tggaaatagg ttggcaattt tggcgctcaa aagaccacct gtttcctatt ggtacttgac
    47101 tattatacac aaaaaaaata caattgtctt gacaattgta ttgacacttg ttagaattaa
    47161 aaatgaggta ttcaggcttg tgatttccta tggaagttaa tagtgattgc ctctaatgct
    47221 tacaagtgat attaaaaata gaggacctag tgatgtcaat catttcaact gatttaaccc
    47281 cttttcaaat agatgataca ttgaaagcag ccttgcgaga agatgttcac tccgaagatt
    47341 acagtaccaa tgccattttt gatcatcatg gccaagccaa ggtgtcgctt tttgccaagg
    47401 aagctggtgt tttagcgggg ctaaccgttt ttcaaagggt ttttacccta tttgatgccg
    47461 aggtgacctt ccagaatcct catcaattta aggatgggga tcgtttgact agtggcgatt
    47521 tggttttaga aatcataggc tcggtgagaa gtctcttaac atgtgaacgc gttgccttga
    47581 attttttaca acatttatca gggattgctt ctatgacagc tgcttatgta gaagccttag
    47641 gcgatgattg cattaaggta tttgatactc gaaaaactac tcctaattta cgtctttttg
    47701 agaaatatgc cgtgagagtt ggcggtggct ataatcatcg ctttaattta tcagatgcta
    47761 tcatgctaaa agacaatcac attgcggcag taggtagtgt tcaaaaggca attgctcaag
    47821 cgcgtgccta tgcccctttt gtgaaaatgg tcgaggtgga agtggaaagc cttgctgctg
    47881 ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt ggataatatg tcattggaac
    47941 agattgaaca ggccattacc ctaattgcag gacgttctcg gattgaatgt tctggaaata
    48001 ttgatatgac cactattagc cgttttcgtg gtttagcgat tgattacgtc tccagtggta
    48061 gtttaaccca tagtgctaag agtcttgatt tttccatgaa gggtttaacc taccttgatg
    48121 tctaagttgt aaaataaact aactttttaa aggatgtctt tcctctagaa cgagttttat
    48181 gtcagatagt ttaaacgcct cttcaaatat agtaaaatga accaaaaata gtacacaatg
    48241 tggtataatc ttcttatggc atattcaata gattttcgta aaaaagttct
//
LOCUS       DAVHBD010000012        46172 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000012 DAVHBD010000000
VERSION     DAVHBD010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46172
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.012"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            389..1567
                     /locus_tag="VVK04_000704"
     CDS             389..1567
                     /locus_tag="VVK04_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU3989392.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            1881..2012
                     /locus_tag="VVK04_000705"
     CDS             1881..2012
                     /locus_tag="VVK04_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU3989393.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2033..3583
                     /gene="dltA"
                     /locus_tag="VVK04_000706"
     CDS             2033..3583
                     /gene="dltA"
                     /locus_tag="VVK04_000706"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU3989394.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3580..4824
                     /gene="dltB"
                     /locus_tag="VVK04_000707"
     CDS             3580..4824
                     /gene="dltB"
                     /locus_tag="VVK04_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU3989395.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVCYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKKRKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4838..5077
                     /gene="dltC"
                     /locus_tag="VVK04_000708"
     CDS             4838..5077
                     /gene="dltC"
                     /locus_tag="VVK04_000708"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU3989396.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5070..6338
                     /gene="dltD"
                     /locus_tag="VVK04_000709"
     CDS             5070..6338
                     /gene="dltD"
                     /locus_tag="VVK04_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU3989397.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6493..6933
                     /gene="adcR"
                     /locus_tag="VVK04_000710"
     CDS             6493..6933
                     /gene="adcR"
                     /locus_tag="VVK04_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU3989398.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6933..7637
                     /locus_tag="VVK04_000711"
     CDS             6933..7637
                     /locus_tag="VVK04_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU3989399.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7630..8436
                     /locus_tag="VVK04_000712"
     CDS             7630..8436
                     /locus_tag="VVK04_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU3989400.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8446..9951
                     /gene="adcA"
                     /locus_tag="VVK04_000713"
     CDS             8446..9951
                     /gene="adcA"
                     /locus_tag="VVK04_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU3989401.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGISQEALFEEMDNWPTYYPDNLSGQEIAQEMLVH"
     gene            complement(11069..11842)
                     /locus_tag="VVK04_000714"
     CDS             complement(11069..11842)
                     /locus_tag="VVK04_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU3989402.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            12018..13421
                     /locus_tag="VVK04_000715"
     CDS             12018..13421
                     /locus_tag="VVK04_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU3989403.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13536..14174
                     /locus_tag="VVK04_000716"
     CDS             13536..14174
                     /locus_tag="VVK04_000716"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU3989404.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14186..14626
                     /locus_tag="VVK04_000717"
     CDS             14186..14626
                     /locus_tag="VVK04_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU3989405.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14619..15050
                     /locus_tag="VVK04_000718"
     CDS             14619..15050
                     /locus_tag="VVK04_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU3989406.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            15041..15511
                     /locus_tag="VVK04_000719"
     CDS             15041..15511
                     /locus_tag="VVK04_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU3989407.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15536..16309
                     /locus_tag="VVK04_000720"
     CDS             15536..16309
                     /locus_tag="VVK04_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU3989408.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16306..17106
                     /locus_tag="VVK04_000721"
     CDS             16306..17106
                     /locus_tag="VVK04_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU3989409.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17165..19459
                     /locus_tag="VVK04_000722"
     CDS             17165..19459
                     /locus_tag="VVK04_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU3989410.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19469..22585
                     /locus_tag="VVK04_000723"
     CDS             19469..22585
                     /locus_tag="VVK04_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU3989411.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            22642..24408
                     /locus_tag="VVK04_000724"
     CDS             22642..24408
                     /locus_tag="VVK04_000724"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU3989412.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            24554..25705
                     /locus_tag="VVK04_000725"
     CDS             24554..25705
                     /locus_tag="VVK04_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU3989413.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPCAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            25850..26734
                     /locus_tag="VVK04_000726"
     CDS             25850..26734
                     /locus_tag="VVK04_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU3989414.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            27178..27429
                     /locus_tag="VVK04_000727"
                     /pseudo
     CDS             27178..27429
                     /locus_tag="VVK04_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            27417..27707
                     /locus_tag="VVK04_000728"
     CDS             27417..27707
                     /locus_tag="VVK04_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989415.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQTEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQKLMNKAVKDEVAQI"
     gene            complement(28112..29443)
                     /locus_tag="VVK04_000729"
     CDS             complement(28112..29443)
                     /locus_tag="VVK04_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU3989416.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(29465..30976)
                     /locus_tag="VVK04_000730"
     CDS             complement(29465..30976)
                     /locus_tag="VVK04_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU3989417.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(31187..32134)
                     /gene="arcC"
                     /locus_tag="VVK04_000731"
     CDS             complement(31187..32134)
                     /gene="arcC"
                     /locus_tag="VVK04_000731"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU3989418.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(32299..33315)
                     /gene="argF"
                     /locus_tag="VVK04_000732"
     CDS             complement(32299..33315)
                     /gene="argF"
                     /locus_tag="VVK04_000732"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU3989419.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(33373..34602)
                     /gene="arcA"
                     /locus_tag="VVK04_000733"
     CDS             complement(33373..34602)
                     /gene="arcA"
                     /locus_tag="VVK04_000733"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU3989420.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            35357..37036
                     /locus_tag="VVK04_000734"
     CDS             35357..37036
                     /locus_tag="VVK04_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU3989421.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPTLSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKIRVVITESQALPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(37076..39160)
                     /locus_tag="VVK04_000735"
     CDS             complement(37076..39160)
                     /locus_tag="VVK04_000735"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU3989422.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPLGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEGGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            39331..40611
                     /locus_tag="VVK04_000736"
     CDS             39331..40611
                     /locus_tag="VVK04_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU3989423.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLSYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     SNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            40702..43347
                     /locus_tag="VVK04_000737"
     CDS             40702..43347
                     /locus_tag="VVK04_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU3989424.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            43431..44300
                     /locus_tag="VVK04_000738"
     CDS             43431..44300
                     /locus_tag="VVK04_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU3989425.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLTWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            44294..>46172
                     /locus_tag="VVK04_000739"
     CDS             44294..>46172
                     /locus_tag="VVK04_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU3989426.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEFYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
BASE COUNT        14002 a         8357 c        10059 g        13754 t
ORIGIN      
        1 actcccctga aatttatttt aattatgcaa atttcacgta tttttgatgc tgagacgacg
       61 atcctgggaa cttttcagat atttttttga ctatctaaat ctatcattag aaaagcttag
      121 agcgccaaag gatttgagcg tttttctgat ttttaagact ttttccagtc tctttttcga
      181 ttgaagatgt aattattcta ctaactaact aacttcttag tactagccaa caacgataat
      241 cataattcct cctaaaatta ggaataataa aggcaatagt ttttgttttt tcatgtaaaa
      301 aacctcactt ttgttttctg ctattttatg ctaaaatatt aaaaatcaaa tttaattcca
      361 aagtttgtaa ctaaaggggg agcgctacat gtctaattca tttgtcaagt tgttagtctc
      421 tcaattattt gcaaatttag cagatatttt ctttagagta acaatcattg ctaacatata
      481 cattatttca aaatcagtaa ttgccacatc actagttcct atcttaatag gaatatcctc
      541 ttttgttgcg agtcttttag ttccgttggt tactaaaagg ttagcgctaa atagggtttt
      601 atctttatct caatttggaa agactatatt attggcgata ctggtaggaa tgtttaccgt
      661 aatgcaatcc gtagcgcctt tggtgaccta tctatttgtt gttgcaattt ccatactaga
      721 tggttttgca gcacccgttt cctatgctat tgtgccacgc tatgcgaccg atttgggtaa
      781 ggctaattca gccttatcaa tgactggtga agctgttcaa ttgataggtt ggggattagg
      841 tggactcttg tttgcaacaa ttggtctgtt acctaccacg tgtatcaatt tagtcttgta
      901 tatcatttct agctttctga tgttatttct tcctaacgct gaagtggagg tgttagagtc
      961 agaaactaat cttgaaattt tgctcaaagg ttggaagtta gttgctagaa atcctagatt
     1021 aagacttttt gtatcagcaa atttattgga aattttttca aatacgattt gggtttcttc
     1081 cattatactt gtttttgtaa cggagttatt aaataaaacg gaaagttact ggggatattc
     1141 taatacagca tactctattg gtattataat tagtggctta attgctttta ggctatctga
     1201 aaagttcctt gctgctaaat gggaaagtat tctttttcct cttgtagcta tggcaatagt
     1261 gacactgact attctatatt ttccaaacgc acagatgttt ttattatttt cagctttagt
     1321 tggtatgtta tcgcaactaa aagaagttcc tgaaagtgta tttcttcagg aaacagtaga
     1381 ggaaaatcat ttagttaatg tctattccgt tcttgaagtg atttctacat tagcattttc
     1441 agtatttgtt ttgctaatga gctatattac tgagagtttt ggtattagca tcagtttttg
     1501 gctatcagcc atttgtctga tgatagaagc tattttaatt tatatcagac gagattattt
     1561 taaatgagag agtggttaaa aagtctttaa aaatcagaaa agcgcatagt atcaggtgtt
     1621 gaaaaaactt gatattgtgt gttttattat gggaagattt acttcattgt ctcctgaaat
     1681 ggagttttga agcaggatca ctctatttga aaatatacat agaaaaactg tataatcctt
     1741 aaaataagct gaaatctatt ggaaacatac ggtaaacaat tgaaaagata ctatataaag
     1801 tggtacaatg gtagaaaaat aagctagtaa gaatcactct tattttagcg aaaaattaca
     1861 gaaatgaatg gtttttcttg atgaaacaga gaaaagaatt gtacctcttt cttggtcgga
     1921 cagccttgta ttttcttatc tttctagggc tgctttactt ctttagctat cttggtcagg
     1981 gtcaaggaag ctttatctat aatgaatttt aacttgaagg agaatcccta ttgtgtcaaa
     2041 taaaccaata gcagatatga ttgaaaccat tgagcatttt gctcagacac agcctagcta
     2101 tcctgtctat aatgttttgg ggcaggaaca cacttatggc gatttaaagg ctgattcgga
     2161 tagtttggct gcagtcattg accaactagg cttgcctgag aagtctcctg tggttgtttt
     2221 tggtggccaa gaatatgaaa tgttggcaac ctttgtagcg ctgactaagt caggtcatgc
     2281 ctacattcca attgatagcc attcggcctt ggagcgagtt tcagctattt tagaagtagc
     2341 agagccaagc ttgattattg ccatttcagc ctttcccttg gagcaggttt ctacaccaat
     2401 gataaatcta gctcaggttc aagaagcctt tgcccaaggg aacaactatg aaatcacgca
     2461 tccagtcaag ggagatgata attactacat tatctttact tctggtacga ctggtaagcc
     2521 taagggagtg cagatttcac atgataatct cctcagcttt acaaactgga tgattacgga
     2581 taaggaattt gcgacaccga gtcgtccgca aatgctggca cagccacctt attcttttga
     2641 cttgtctgtc atgtattggg caccgacctt ggcacttggt ggtacgcttt tcactcttcc
     2701 ttcagtcatc actcaggact ttaagcaact ctttgcggct atcttttcat tgccaatcgc
     2761 tatctggaca tcaacaccat cctttgcaga tatggccatg ttgtctgaat acttcaacag
     2821 tgagaaaatg cctggaatca cgcatttcta ctttgatggt gaagaattga cggtcaaaac
     2881 agctcaaaaa ctgcgcgagc gtttcccaaa tgcccgtatc atcaatgctt acggcccaac
     2941 agaagcgaca gtagctctgt cagcagttgc cgtgacagac gagatgttag cgactctcaa
     3001 acgcctacca atcggctata ccaaggctga ttctccaacc tttatcattg acgaggaagg
     3061 aaataaactg ccaaatggcg aacagggaga aatcattgtt tctgggccag ctgtttcaaa
     3121 aggttatatg aaaaatcctg aaaaaacagc agaagccttc tttgagtttg aaggtctgcc
     3181 agcctatcac acaggcgatg tgggaaccat gacagatgag ggcttgcttc tctacggcgg
     3241 acgcatggac ttccagatta agtttaacgg ttaccgcatt gagttagaag atgtctctca
     3301 aaacctcaac aagtctcgct ttatcgaatc tgctgtcgca gtaccgcgct ataacaagga
     3361 ccacaaggta caaaatctat tggcttatgt catcttaaaa gacggtgttc gtgagcagtt
     3421 tgagcgagat atcgatatta ccaaggccat caaggaagac ctgacagaca tcatgatgtc
     3481 ctatatgatg ccatctaaat tcctttaccg agacagtttg ccactaactc caaatggaaa
     3541 gattgacatc aaaggattga ttaacgaggt gaataagaga tgatggagtt ttttcaacag
     3601 cttcctcatt tagagccata tggcaatcct cagtattttg tttatgtgat tgctgcaacc
     3661 ttgcccatct ttataggcct ctttttcaag aaacgctttg cctggtatga agtgttggta
     3721 agtctcttct ttattgtcac catgttggtg ggtggaaaga ccaatcaact agctgccttg
     3781 ggtatttacc tttgctggga aatattgctc ctgcttttct acaagcatta tcgaaaaagc
     3841 aaggatggca agtgggtctt ctacttagtt agttttctgt ccctacttcc gattatcttt
     3901 gtcaaggtgc aaccagctat caatggaacg cagtctttgc ttgggttctt gggaatttct
     3961 tacctgacct ttcgttcggt tgggattatc atcgagctga gagatggagt gattaaggat
     4021 tttaccctct gggaattcct ccgtttcctt ctcttcatgc caactttctc gagtggtcca
     4081 atcgatcgct ttaagcgatt taatgaaaat tatcaggcca ttcctgagcg agatgagttg
     4141 atggatatgc tggatgaatc tgtctgctat atcatgcggg gctttttgta taagtttatc
     4201 ctagctcatg ttttaggaga gaccttactc cctcctctga agaatttagc cttgcagtca
     4261 ggtggcttct ttaatctcta tgccttggca gttatgtata cttttggtct ggagctcttc
     4321 tttgactttg caggttattc tatgtttgct ttggccatct caaacttgat gggaatccgt
     4381 agccctatca actttaacaa gcccttttta tcaagggatt taaaggaatt ttggaatcgc
     4441 tggcatatga gtctgtcttt ctggttccgt gactttgtct ttatgcgaat ggtgatggtg
     4501 ttaaccagaa agaaagtctt taaaaatcgt aatgtaacct caagcatggc ctacattgta
     4561 aatatgctga ttatgggatt ttggcatggc gtgacctggt actatatcgc ctatggactc
     4621 tttcatggac taggcttggt catcaatgat gcctgggttc gcaagaaaaa aacgctcaat
     4681 aagaaacgga aaaaagcagg gaaggctgcc ctacctgaga atcgctggat tcagtttctt
     4741 ggcatggttg tcactttcca tgttgtcatg ttgtcattct taatcttttc tggattcttg
     4801 aataatctat ggtttaaaaa ataaaaggaa ataaaatatg gatatcaaat cagaagttat
     4861 tgaaattatt gatgagttgt ttatggaaga tgtttctgac atgatggatg aagatctttt
     4921 tgatgcaggt gtcttggata gtatgggaac ggttgagttg attgtggaga ttgagaaccg
     4981 ttttgacatt cgtgtccctg taacagagtt tggtcgtgac gactggaata cagctaataa
     5041 aatcatagct ggtattgtgg agctacaaaa tgcttaaacg cttatggatg atcttcggac
     5101 cggtcttgat cgctggtttg ttggtttttc tgctcatttt cttttatcct actgagatgc
     5161 atcataatct aggagctgaa aagcgttcag cagtggctac tactatcgat agttttaagg
     5221 agcgaagtca aaaagtcaga gcactatctg atccaaatgt gcgttttgtt cccttctttg
     5281 gctctagtga atggcttcgt tttgacggtg ctcatcctgc ggtattagct gagaaataca
     5341 atcgttccta ccgtccttat cttttaggac aggggggagc tgcatcgctt aaccaatatt
     5401 ttggaatgca acagatgtta ccacagctgg agaataaaca agttgtgtat gttatctcac
     5461 ctcagtggtt cagtaaaaat ggctatgatc cagcagcctt ccagcagtat tttaatggag
     5521 accagttgac tagttttctg aaacatcaat ctggggatca ggctagtcaa tatgcagcga
     5581 ctcgcttact gcaacagttc ccaaacgtag ctatgaagga cctggttcag aagttggcaa
     5641 gtaaagaaga attgtcgaca gcagacaatg aaatgattga attattggct cgttttaatg
     5701 aacgccaagc ctcctttttt ggtcagtttt cggttagagg ctatgttaac tacgataagc
     5761 atgtagctaa gtatttaaaa atcttgccag accagttttc ttatcaagca atagaagatg
     5821 ttgtcaaagc agatgctgaa aaaaatactt ccaataatga gatgggaatg gaaaattatt
     5881 tctataatga gcagatcaag aaggatttga agaaattaaa ggattctcag aaaagcttta
     5941 cctatctcaa gtcgccagag tataatgact tgcagttggt tttaacacag ttttctaaat
     6001 ctaaggtaaa cccgattttt atcattccac ctgttaataa aaaatggatg gactatgctg
     6061 gtctacgaga ggatatgtac caacaaacgg tgcagaagat tcgctaccag ttagaaagtc
     6121 aaggttttac caatatagca gatttttcta aggacggcgg ggagcctttc tttatgaagg
     6181 acaccattca ccttggttgg ttgggttggt tggcttttga caaggcagtt gatcctttcc
     6241 tatccaatcc cacaccagct ccgacttacc atctgaatga gcgctttttc agcaaagatt
     6301 gggcgactta tgatggagat gtcaaagaat ttcaatagat aatataatat agaagagttc
     6361 aagaatgaaa ctagttttca cgttttttct tgactctttt tttgcttgtg atataattaa
     6421 ctggtaaaca aaatgtcaaa gaatagtatt tttctcttaa aaaagagaag tctaaaagga
     6481 aaggagtcag atatgagaca gctagcaaag gatatcgatg cttttttgaa tgaggtgatt
     6541 ttgcaggcgg aaaatcagca tgaaatccta ataggtcatt gcactagtga ggtggccctg
     6601 accaatactc aggagcatat ccttatgctc ttgtcagagg aatctttaac aaattcagaa
     6661 ttggcccgtc gtctcaatgt cagtcaggcg gcagttacca aggccattaa gtctttggtc
     6721 aaggaaggga tgttggaaac atctaaagat tctaaagatg cgcgtgtgat tttttatcag
     6781 ttgactgact tggctcgtcc aatcgctgag gagcaccacc atcaccatga gcatacactt
     6841 ttaacctatg aacaagtggc gactcagttt actccaaatg aacaaaaagt gattcagcgg
     6901 tttttgactg ctttagtagg agaaatcaaa taatgagata tattacggta gaggatttgt
     6961 ccttctatta tgataaggag cctgttcttg aacatatcaa ttatagtgtt gatagtgggg
     7021 aatttgttac cttgactggg gaaaatggag cggctaagac gacgctcatc aaggccagtc
     7081 ttggaattct gcaaccacgc attggaaagg tggctatttc aaagacaaat acgcaaggta
     7141 agaaattgag aatagcctat cttcctcaac aaattgccag ttttaatgct ggttttccaa
     7201 gtacggtcta tgaatttgtc aagtcgggtc gctatccgag aaaaggctgg ttccgtcgtt
     7261 tgaatgctca tgatgaggag catatcaagg ctagtctgga ctcagttggc atgtgggaac
     7321 atcgagacaa acgcttgggg tctctatctg ggggacaaaa gcagcgagcg gtaattgcgc
     7381 gtatgtttgc ttctgaccct gatgtgttta tcctagacga gccgacaacg gggatggatg
     7441 caggaagtaa aaatgaattt tacgaactca tgcaccacag cgcccatcat catggcaagg
     7501 ctgttttgat gattacccat gaccctgaag aagttaagga ttatgcggat cgcaatattc
     7561 atctagtccg taaccaagac tcgccatggc gttgtttcaa cgttcatgag aatggccagg
     7621 aggtgggcca tgcttagttt attatcttac gactttatac aacgcgcctt tttggcggtt
     7681 attgctatga gtcttttctc accggtattg ggaaccttcc tcatcttgcg tcgtcagagt
     7741 ttgatgagtg atacccttag ccacgtctca ctttcaggtg tagcctttgg tctggttttg
     7801 gggatttctc caactgtttc tactattgcc attgtcttga ttgcggcggt ctttctggag
     7861 tatctccgta cagtttacaa gagctttatg gaaatcggga cagctatcct catgtcaaca
     7921 ggtctggctg tttctctgat tgtcatgagc aagggtaaaa gctcgagttc aatgagtttg
     7981 gaccaatatc tctttggttc gatcgtgact atcagtgaag aacaggtcat ttccctcttt
     8041 gtcattgcgg cggttgtttt gattttgacc tttctctttc ttcgtcctat gtatatctta
     8101 acttttgacg aagatacggc ctttgtggat ggcttgccag ttcgtaccat gtccattctt
     8161 tttaacatgg tgacaggggt ggctattgcc cttatgattc ctgcagcagg agctcttctg
     8221 gtatcgacca ttatggtctt gccagctagt attgccctgc gtctggggaa aaactttaaa
     8281 tcggttatgc tgcttgccag tgcgattggc tttttgggaa tggtagcagg actttatatt
     8341 tcctactatg cagaaacacc tgcaagtgca agtattacca ttatttttgt aactgtcttt
     8401 atactaatca gtttagtaag acgttttatc aaataggaga cgaacgtgaa aaaaattagc
     8461 ttattactag ccagtctatg tgccttgttt ttagtggctt gttccaatca aaaacaggca
     8521 gatggtaaac tcaatatcgt gacaaccttt taccctgtct atgaatttac caagcaagtc
     8581 gcaggagata cggctaatgt agaactccta atcggtgctg ggacagaacc tcatgaatac
     8641 gaaccatctg ccaaggcagt tgccaaaatc caagatgcag ataccttcgt ttatgaaaat
     8701 gaaaacatgg aaacatgggt acctaaattg ctagatacct tggataagaa aaaagtgaaa
     8761 accatcaagg cgacaggcga tatgttgctc ttgccaggtg gcgaggaaga agagggagac
     8821 catgaccatg gagaagaagg tcatcaccat gagtttgacc cccatgtttg gttatcacca
     8881 gttcgtgcca ttaaactagt agagcacatc cgcgacagct tgtcagcaga ttatcctgat
     8941 aaaaaagaga cctttgagaa gaatgcagct gcctatatcg aaaaattgca agccttggat
     9001 aaggcttacg cagaaggctt gtctcaagca aaacaaaaga gctttgtgac tcaacacgca
     9061 gcctttaact atcttgcctt ggactatgga ctcaaacaag tcgcaatctc aggactttct
     9121 ccagatgcag agccatcagc tgctcgcttg gcagaattga cagagtatgt caagaaaaat
     9181 aaaatcgcct atatctattt tgaagaaaat gcctcacaag cccttgctaa cacactttca
     9241 aaagaagcag gtgtcaaaac tgatgtcctc aatcctttag aaagtctgac agaagaggac
     9301 accaaggctg gagaaaacta catttccgtg atggagaaaa acctcaaggc tttgaaacaa
     9361 acaacagacc aagaaggccc agcaatcgaa cctgaaaagg cagaggatac caagacagtc
     9421 caaaatggtt acttcgagga tgcagctgtc aaggaccgca ccttgagtga ctatgcaggt
     9481 aactggcaat cagtttatcc tttccttgaa gacggcacgt ttgaccaagt ctttgactac
     9541 aaggctaagt tgactggtaa gatgacccag gctgagtaca aggcttacta tacaaaaggc
     9601 tatcagacag atgtgactaa gattaacatt actgataata ctatggaatt tgttcaaggt
     9661 ggacaaagca agaaatacac ttacaagtat gtcggtaaga aaattttgac ttacaagaaa
     9721 ggcaatcgtg gcgtgcgttt cctctttgaa gccacagatg ctgacgctgg acaattcaag
     9781 tatgttcagt ttagtgacca caatgttgcc ccagttaagg cagaacattt ccatatcttt
     9841 tttggaggca taagccaaga agccctcttt gaagaaatgg acaactggcc aacctactac
     9901 ccagataacc tatctggcca agaaatcgcc caagaaatgt tggtgcattg atgagaaatc
     9961 gactagttca taagagctag tcggtttttt gatactagat ggctaacttc attatagacc
    10021 tttcagaact ttaaacaata aataaaactc ttgaaatatc tggacttata tgctagaatg
    10081 tagttagtgt ataaggttca ttagaacacc aaagccccta actagtgcca tagttaaggg
    10141 cttttttgac gtatcttagc gatttaacgg gtgtttatag gctagtcagt cggtctactt
    10201 cttaccatct agccatttgc agacgaaata caagataatt ccagctataa catctgctat
    10261 aatagtaaga gcaagctctg gtataaggct cattagtttc acctcctctc acgaacccat
    10321 aggaacgtaa tcggtaaccg atgacaaaag tattatacca cactaaattt agatcatcaa
    10381 cctcacttaa tgcttgaact attgtagatt atatgctaaa atgtggttaa ttgataaggt
    10441 tcattagaac accaaagccc ctaactatgg ccgtagttaa gggctttttt gacgtatctt
    10501 agcgatttaa cgggtgttta taggctagtc agtcggtcta ctccttacta tctagccatc
    10561 tgcagacgaa atacaagata attccagcta taacatccgc tataatagta agagcgagct
    10621 ctatgataag gctcattagt ttcacctcct ctcacgaacc cataggaacg taatcggtaa
    10681 ccgatgacaa aatagtatac cacaatacat ttagatcatc aaggtcattt aattcttgaa
    10741 atatagggtc taggcgacaa agtctttaaa atcagaaaaa cgcataatat caggtgtgca
    10801 aaaacttgat actatgcgtt ttattgtggg aaggtttact ccattttctc ctgaaattga
    10861 gtttttgtcc agcctctgtt tttagggttg ctaagaaaat aatgtcatgt ggtgaatatt
    10921 tgtaaatcag tcagcagaca gaacgatact cttcgaaaat ctcttcacat catgtcagct
    10981 tcgtctttcc gtgtccatgg gggacttgac ttcatcagtt ttcaaatctg tactttgagc
    11041 aagctgagac tagcttccta tttgattttc attgaatatc agaaacccat tctccatcaa
    11101 ataattcgac tgcgtctaat aatttttgat ctggcacggt gtcagaaata aaggttgtgt
    11161 atttggatag gggattaatt ttaaaaaatc cagtcttgta aaatttagaa ctatcaatca
    11221 gtaagatggt ttcatgggct ttgtcaataa tattcttttt tgaaatagct tggctgagag
    11281 aagcttcata aacatattgg tcatcaatac ctcttgctga acaaaatgct aaatcgatat
    11341 taaaatgatc taataaagaa ttttccttat catagttgac cacggaacag gattgatgtt
    11401 tgacctcgcc agatgtgata aagattttgg agctatcttt aacagtttca gatagggttt
    11461 gtgcagtatg taaaccattt gtaaaaataa tcaaattatc aagttcagaa agatagggac
    11521 agagttcgta gacagtagta ctggaatcca gatagataca cataccagac cgaataaagt
    11581 ctttagcgag actagcgatt agtctttttt gcctagtact ttctccttcc cgtatttgat
    11641 gagaaagttc aattgtgttc atagaggaca gggtcacgta tccgtgcttt cttttgataa
    11701 gaccttgatt ttctaagaaa attaaatcac gacgtaaggt acttgtgctg gagaaagtga
    11761 tttctgccag ctcttttacg gcaattcttt ttttcttttt aataatttca atcaattcaa
    11821 gtacacgttc atcttttatc ataagctcct cctaatttat catttcaact atattatagc
    11881 acaaattgga ggaatttgaa ttatttttat gaatattggg ttaacatttg aacattattc
    11941 aagtaagcgt tcacatattg aaaaaataaa atgtggggat tataataaag ttaatcaagg
    12001 acgaagagag aagaaaaatg gaagcggttt tagcaataga tttaggtgcg acttctggaa
    12061 gagcaatcgt tggttacctt tctgaaaata aactagtaat ggaagaaata aatcgctttt
    12121 ctaatctacc tattagagta aaagggcatt tatcttggga tattgacttt ctactagcta
    12181 aaattcttga aagtatccgc ttggctaata ctagttacaa gattttatct atcggtattg
    12241 acacatgggg agttgatttt ggactgattg ataatgaagg taagctgtta tcacaacctg
    12301 ttcattatcg tgatgaaaga acaaagggag tgttaaagga aatatctgaa atgactgaat
    12361 tagaaaaact gtattcagag acaggaaatc agattatgga gataaatacc ttgtttcaac
    12421 tctttaaggc acgtcaagaa tctcctgact ctttctataa gaccaataag attcttttaa
    12481 tgccagattt gtttaattat ctcttgacag gtaagtttgc tacagaaaaa agcattgctt
    12541 caacaactca attatttgat cctaggagtc aaaattggaa tcagaatatc ttaaaactat
    12601 ttgaattgga ttcatcttta cttcctgaaa ttgtttcaga gggaaatgtt cttggaagga
    12661 taaaaaagga gtatggttta ggcgatattc ctgttgtgaa tgtttgtagt catgatacag
    12721 caagtgcgat tgtctcagta cctaagacag aaggtagttt atttatttca tcaggtactt
    12781 ggtctttggt tggagtggaa cttacttcac cgattcttac taccgaatcc ttcagttatg
    12841 gatttacaaa tgaagtcggt aaagatggag agattacatt tctgaagaat tgtacagggt
    12901 tgtggatcat agaggaacta agacgttcat ttgaacgaag agggaaagcc tattcttttg
    12961 atgatattag gacaatggtg gagaaagaaa aagaaaatct tcctctgatt gatactgaat
    13021 caactgaatt tgcaacagaa tctgatatgc acaagacttt gacagaatat ctagcttatc
    13081 atcatgaaac tagagagtgg acagatggac aactatttaa gattgtttat gaaagcctag
    13141 ctgaaacgta taggaaagcg atagagttat tagaagaact aactcataag gtttataaga
    13201 ggatatatgt gattggagga ggtgctagag ccagttactt taaccaaatg attgctgata
    13261 gaactggtaa agaggttctt acaggttcga ctgagggtac agctgtgggg aatattgttg
    13321 tgcagctcat agctatggga caattaaaag ggatggaaga agctcaccat gttattgagg
    13381 agttcctaca attagagagt tattactccc aaaagaatta aaaagattga gagtttgtaa
    13441 atttgcctcc ctcccccttc ttagcttttg tgcaggaagg ggggataatt ggtgaattga
    13501 aaaatattta gtgttttgat atgaggagga caaggatgtc agatgtaaaa caagaattaa
    13561 ttaaatatgg taagaagcta gtagaaacag atttgacgaa aggaacaggt gggaatctca
    13621 gcgttttcga tcgtgaaaaa caattgatgg caattacccc gtcgggtatt gatttctttg
    13681 aaatcaaaga atccgatatt gtagtgatgg atattaatgg aaatgttgta gagggagaac
    13741 gcttgccatc tagcgaatgg tatatgcatt tgattcaata tcaaactcgt gatgatatcg
    13801 atgcaattat ccatgctcat acaacttatg caacagtatt agcttgtctc agagaaccac
    13861 ttccagcgag tcattatatg attgcagtgg cagggaaaga tgttcgggta gctgagtatg
    13921 caacatatgg tacgaaagaa ttggctgtga atgcagctaa agcaatggaa ggtcgtagag
    13981 cagttttact agcgaatcat ggaattttag caggtgcaca aaatttattg aatgcattta
    14041 atattgttga agaagttgaa tattgtgcaa aaatttattg tttagctaag aattttggag
    14101 agccagtagt tcttcctgat gaggagatgg aattgatggc agaaaaattt aaaacatacg
    14161 gtcagagaaa atagggagga tattaatgtt aaaacatata ccgaaaaata tttctccaga
    14221 tttattgaag actttaatgg aaatgggaca tggagatgaa atagtattag ctgacgcgaa
    14281 ttatccttct gcctcatgtg caaataagct aattcgttgt gatggtgtaa atattccaga
    14341 attattagat tccattctgt atttaatgcc attagatagt tacgtcgata gttcaattca
    14401 gtttatgaac gttgtttcgg gtgatgatat tcctaagata tggggtacct atagacaaat
    14461 gattgaaggt catggtacag atcttaaaac gattacttat cttagaagag aagactttta
    14521 tgaacgtagt aagaaagctt atgctattgt tgctacagga gaaacttcac tttatgctaa
    14581 tattatcctt aagaaaggag tagttgttga aagagaaaat gtttaataga ggaattttag
    14641 ttgccagtca tggtaatttt gctagcggag ctctcatgac cgcagaaatg tttgttggtg
    14701 agacaacaaa tgatagagtt aggacattag gtttgatgcc tggagagaat attgtagagt
    14761 ttgaacatta ttttaaaaat caagtaaatg aactgttaga ctcaaatcaa gaggttatcg
    14821 ttttgactga cttgattgga ggaagtccta ataatgtggc tttgtcacgg tttttaaatt
    14881 tggattcagt tgatattgta acagggttta atatccctct cctagtggaa ttaatatcaa
    14941 gttatgattc aaaaatcaat ttagaagaaa ttgttcacaa tgctcaaaat agtttgttta
    15001 atgttaaaca acaacttaac gtagaggagg aagaggattt atgtctatag agtttgttcg
    15061 tattgatgac cgtctggtac atggtcaagt tgtcactacg tggctaaaaa agtatgatat
    15121 tgagcaagtt atcattgtta atgatcgcat ctcagaagat aaaacacgac aatctatttt
    15181 aaagatttct gcaccggtag gtttaaaaat tgttttcttt agtgtaaaac ggtttgtgga
    15241 agttttaaac tctgtgccaa taaaaaagag aacaatgctg atatatacaa atccaaaaga
    15301 tgtgtatgat tctattgaag gaaatttaaa attggagtac ctcaatgtag gacagatgag
    15361 taaaacggag gaaaatgaaa aggtaacggg aggtgtagct ctaggtgaag aagacaaata
    15421 ttattttaag aaaatagttg ataagggaac gagagttgaa attcaaatgg ttcctaatga
    15481 taaagttaca atgttggaaa aatttttata aaaataattt aaggaggtac agtatatgct
    15541 attcacacaa gcattactgg tgacattagt tgggattatt gccactattg actataatgg
    15601 accgttattt atgattcacc gtccgttagt tacaagtgca atggttggct tagtcttagg
    15661 agatttcacc caaggtgttc ttattggttc agctcttgaa ttaacttggc tcggtgtaac
    15721 aggtattgga ggttacactc caccagatac tatttcaggt gcgattattg gtactgcatt
    15781 tggtattttg tctggtcaag gagaaactgc tggtatcgct atagcagttc caattgcagt
    15841 tgctactcaa cagttggatg ttcttgcaaa aactttagat gtttattttg tgaaaaaagc
    15901 tgataatgat gctaaaaacg gagattattc aaagatcggt ttttatcatt attcaagttt
    15961 ggttttaatc actttattta aaattgtacc aattttccta gctattatgc ttggagggga
    16021 atatgtggca gacttgtttg ctaaggttcc accaatcgtt atgcagggac ttaactctgc
    16081 aggtgcttta ctaccttcaa ttggttttgg tatgctttta aatatgatgc tcaagaaaaa
    16141 tatgtgggta ttcttgttga ttggattcat ttgttctgtg tatggaggaa tgtcaaccat
    16201 tgggatctca ctagttggta ttgcggtagc atacttctac gatatgattg gaagtaaacc
    16261 acaagaaaca acttcaagta gtgatgttga ggaggatctt gatctatgat gaataataaa
    16321 gtaactaaag ttgaacttaa aaaagttttc aaacgaagtt ttatgtatgg ttcttcatgg
    16381 aactatgaga gaatgcagaa cctaggtttt ctatatacaa ttcttccagt attgaaaaaa
    16441 ctatacccag acaaagattc agcttctcct gcaatgaaac gtcaccttga gtttttcaat
    16501 actcatcaaa cagcggcacc atttattctt ggagttactt ccgctatgga agaacaagaa
    16561 ggaaatgaag gtgcagcttc aattactggt attaaagttg gcttgatggg gccactggct
    16621 ggtctaggag atagtttgtt ctggctgaca ctagttccta tctgttttag tattggtgcg
    16681 tcttattcta aagacggcgg tgctttaggt atctttatcg ccttaatatt gtttaatatt
    16741 attaatattc ctgttaaata tttcggtttg aaatatgggt atactaaggg ttctagtctt
    16801 atccaagaaa ataatacaaa aggaacattg aatcgcgtta cgagtatggc gacagcatta
    16861 gggctagtac tagtgggtgg tttgattcca tcaatggttg gtattaattt tggattagaa
    16921 tttaagcagg gggaacttgt tatttctgtt caagaaatga ttacaaaatt aattccagga
    16981 tttatcccca tggctttgac tttattaatg tgtaaattaa ttagaaaagg aaagaatccg
    17041 gttgtactaa tctttagtgt tatggctatt ggagttatcc tagttgtttt aggaattttg
    17101 aagtagtaga aagtgtggag gtggtatttg ggatatcacc tccattttgg aagagaggta
    17161 aagagtgaaa ttatggtata agaaagctgc ctcaaattgg aatgaagcct tgccgattgg
    17221 gaacggtcat ttaggtggta tgatttatgg ttcagctaca aaagaatgta ttcaactaaa
    17281 cgatgagact atttggtata gaggaaagtc agatagaaat aatccagact cactattgca
    17341 tcttaaaaaa attcgggaat atcttttaga tggagaaatt cagaaagccg aagaattgat
    17401 aaagttaaca atgtttgcta ccccaagaga tcaaagccac tatgaattac ttggggaact
    17461 ttacattgag catatagata ttcagtcttg tgctctttca ttgtatgaaa gagagctaga
    17521 tttagataca gctatttcta atgttgtgtt tgagcctaat agttgtaatt tacaaataaa
    17581 aagagaatat tttacgagtt ttaataagaa tattttatgt tgccgtatag tgtcatcagt
    17641 tcaaaacaca ttaaatttaa acattaattt gggtagaaat aaacggttta atgacgaagt
    17701 atctaaactg gattcaagta caattttaat gtcggcctct gctggaggta gaaaaggtgt
    17761 tcagtttaaa gtagtatgtc attctaaggt tacggatggt gaagtaagtg tattgggaga
    17821 gacaatagtt attcggaatg ctacagaggt atttctttat ctcaaatcaa tgacggatta
    17881 ttggggaaat atagatattt cttctcttca gggagaattt agtagtattg attactttac
    17941 agaaaaagat gaacatgtaa aaaaatatca ggagcaattt aatagagttg attttaaact
    18001 agactatagt aaaggttgtc ttagcattcc aacgaatcta cttcttgaaa acactaaaaa
    18061 gtatagtaac tacttgacta acttgttatt tcattatgga agatatctgt taatatcgtc
    18121 tagtcaaccg aatggtttac ctgccaatct tcaaggaata tggtgtgatg aattaaatcc
    18181 aatttggggt tctaaatata cgattaatat taatactcaa atgaattatt ggatggtagg
    18241 tccatgtgat ttaccagaag tagaatatcc attatttgat atgctcgaaa gaatgagaga
    18301 accgggaaga ctaaccgcta agaaaatgta tggagctaga ggttttacag cacatcataa
    18361 tacggatggt tttggcgata cggctcccca atctcatgcc atgggggctg caatttgggt
    18421 attaactatt ccatggttat gtactcatat ttgggaacac tatttatatt tccaagatga
    18481 gcgtattctt acggaacatt ttgaaatgat aaaagaagca tttcttttct ttgaagatta
    18541 tttatttgag gtggatggct acttgatgac aggtccaagt gtctcaccgg aaaataaata
    18601 tcgcttaaaa aatggtattg aaggaaatgc ttgtctatca tctacaattg ataatcaaat
    18661 tttaagatat ttttgtgatt catgcattgg aattgcaaaa caattaggag acaattcgga
    18721 ttttattagt cgtgtgaagg agttaaaaaa gaaattacct agaacaaaaa taggtagtaa
    18781 tgggcaaata caagaatggc tagaggatta tgaagaagta gagcctggtc atagacacat
    18841 ttcacctcta tttgggcttt atccttataa tgagattgat attcataaaa ctccggaatt
    18901 agcagaagca gctaaaatca ctatcaatag gagattatca aacgctaact ttttatcttc
    18961 acaggatagg gagcaagcga ttaataattg gttagtaagt ggtttgcatg ctagtacaca
    19021 aacaggttgg agtgctgcat ggctgattca tttttttgcg agactatatc aaggtgaacc
    19081 tgcttataac cagattaatg gtttgttaaa taatgcgact cttggcaatt tatttcttga
    19141 ccatccacca tttcaaattg atggtaattt aggtttggtg agtggaattt gtgaattatt
    19201 agtacagagc catcataatt ggttatcact aattccagct ttaccttctg cttggtcaga
    19261 aggagaagtg aaaggtttca gagtaagagg aggatataag gtatcgtttg cttggaaaaa
    19321 tggggatata acattcctaa aattggaagg aggaaacaaa gatcaaaaag taagagtaag
    19381 aatatatggc aaaaatactg atgtacaaaa tattgaattg gtatttaatt cagaaaaaat
    19441 tattgagtta aatttttagg tataagtcat gaataaagaa aaaataaaaa gaaaattaat
    19501 cacaatactg tttgtatgta ttgggatgtt atgttttgga ttgttagcag gagttaaggc
    19561 tgataatcgt gttcaaatga gaacgacgat taataatgaa tcgccattgt tgctttctcc
    19621 gttgtatggc aatgataatg gtaacggatt atggtggggg aacacattga agggagcatg
    19681 ggaagctatt cctgaagatg taaagccata tgcagcgatt gaacttcatc ctgcaaaagt
    19741 ctgtaaacca acaagttgta ttccacgaga tacgaaagaa ttgagagaat ggtatgtcaa
    19801 gatgttggag gaagctcaaa gtctaaacat tccagttttc ttggttatta tgtcggctgg
    19861 agagcgtaat acagttcctc cagagtggtt agatgaacaa ttccaaaagt atagtgtgtt
    19921 aaaaggtgtt ttaaatattg agaattattg gatttacaat aaccagttag ctccgcatag
    19981 tgctaaatat ttggaagttt gtgccaaata tggagcgcat tttatctggc atgatcatga
    20041 aaaatggttc tgggaaacta ttatgaatga tccgacattc tttgaagcga gtcaaaaata
    20101 tcataaaaat ttggtgttgg caactaaaaa tacgccaata agagatgatg cgggtacaga
    20161 ttctatcgtt agtggatttt ggttgagtgg cttatgtgat aactggggct catcaacaga
    20221 tacatggaaa tggtgggaaa aacattatac aaacacattt gaaactggaa gagctaggga
    20281 tatgagatcc tatgcatcgg aaccagaatc aatgattgct atggaaatga tgaatgtata
    20341 tactggggga ggcacagttt ataattttga atgtgccgcg tatacattta tgacaaatga
    20401 tgtaccaact ccagcattta ctaaaggtat tattcctttc tttagacatg ctatacaaaa
    20461 tccagctcca agtaaggaag aagttgtaaa tagaacaaaa gctgtatttt ggaatggaga
    20521 aggtaggatt agttcattaa acggatttta tcaaggactt tattcgaatg atgaaacaat
    20581 gcctttatat aataatggga gatatcatat tcttcctgta atacatgaga aaattgataa
    20641 ggaaaagatt tcatctatat tccctaatgc aaaaattttg actaaaaata gtgaggaatt
    20701 gtctagtaaa gtcaactatt taaactcgct ttatccaaaa ctttatgaag gagatgggta
    20761 tgctcagcgt gtaggtaatt cctggtatat ttataatagt aatgctaata tcaataaaaa
    20821 tcagcaagta atgttgccta tgtatactaa taatacaaag tcgttatcgt tagatttgac
    20881 gccacatact tacgctgttg ttaaagaaaa tccaaataat ttacatattt tattgaacaa
    20941 ttacaggaca gataagacag ctatgtgggc attatcagga aattttgatg catcaaaaag
    21001 ttggaagaaa gaagaattag agttagcgaa ctggataagc aaaaattatt ccatcaatcc
    21061 tgtagataat gactttagga caacaacact tacattaaaa gggcatactg gtcataaacc
    21121 tcagataaat ataagtggcg ataaaaatca ttatacttat acagaaaatt gggatgagaa
    21181 tacccatgtt tataccatta cggttaatca taatggaatg gtagagatgt ctataaatac
    21241 tgaagggaca ggcccagtcc ctttcccaac accagataaa tttaatgatg gtaatttgaa
    21301 tatagcatat gcaaaaccaa caacacaaag ttctgtagat tacaatggag accctaatag
    21361 agctgtggat ggtaacagaa atggtaattt taactctggt tcggtaacac acactagggc
    21421 agataatccc tcttggtggg aagtcgattt gaaaaaaatg gataaagttg ggcttgttaa
    21481 aatttataat cgcacagatg ctgagactca acgtctatct aattttgatg tgattctata
    21541 tgacaataat agaaacgaag ttgctaagaa acatgttaat aatttgtcgg gtgaatctgt
    21601 tagtctagat ttcaaagaaa aaggagcaag gtatattaaa gttaaattac taacgagtgg
    21661 agtgcctttg agtttagcag aagtagaggt ttttagagaa tcagatggta agcaatctga
    21721 agaggatata gataaaataa cagaagataa agtagtctct acaaataagg tagctactca
    21781 aagttcaacc aattatgagg gtgtagctgc tttagcagtt gatggtaata aagatggaga
    21841 ttacggacat cattcggtga ctcatactaa ggcagattct aacgcttggt ggcaggtcga
    21901 tctgggagaa gagtttacgg tttctaaagt tgatatttat aatagaacag atgccgaacc
    21961 tcagcgttta tctaattttg atgttatttt tctatcttca tcaggagaag aagtttttag
    22021 aagacatttt gataaagtag ttgatggttt gttatcttta aaagtacctt ctgtaggggc
    22081 taagctagtc aaaatagaat taaaatcagc agctattccg ttaagtttag cggaagttga
    22141 agtctatggt tcaaagagaa ctccgaagaa actttctaat attgcattaa ccaaagaaac
    22201 tcgacagagt tcaacggatt acaatggttt ttctcgtcta gcagttgatg gaaataaaaa
    22261 cggagattat ggtcatcatt cagtgactca taccaaagga gattctcctt catggtggga
    22321 gatagattta gcacaaaccg aagaattaga aaagttaatt atttataata gaacagatgc
    22381 tgaaattcag agattatcaa attttgatat tattatatat gattcaaata atcatgaagt
    22441 ttttaaacaa catattgaca gtttagaaag caataatcta tccatagact taaaagggct
    22501 gaagggaaaa aaggttagaa tttctttgag aaacgcagga attcctttaa gtttggcaga
    22561 ggtagaggtt tatacttata agtaatttta aaaattatca tcggtagtat gaaagaaaca
    22621 gaaaaataag aggaaaatag tatgattcaa catccacgta ttgggattcg tccgactatt
    22681 gatggtcgtc gtcaaggtgt acgcgaatca cttgaagtac aaacaatgaa catggctaaa
    22741 agtgtggcag atttgatttc aagcacattg aaatatccag atggggaacc tgtggaatgt
    22801 gtgatttctc catctaccat tggtcgtgtt ccagaggctg cagcttccca tgagttgttt
    22861 aaaaaatcaa atgtttgcgc aacaattaca gttacaccat gctggtgtta tggtagtgaa
    22921 actatggata tgtctccaga tattcctcat gctatttggg gatttaatgg gacagaacgc
    22981 ccaggagctg tctatcttgc agctgtacta gcttcacatg ctcaaaaagg gattccagcc
    23041 tttgggattt atggtagaga tgttcaggaa gctaatgata cagatattcc agaagatgtc
    23101 aaagaaaaac ttttacgtta tgcgcgtgca gctcttgcaa ctggcttgat gagagacact
    23161 gcttacctat caatgggtag tgtttcgatg gggattggtg gttctattgt aaatccggat
    23221 ttcttccaag aatacttagg aatgcgaaat gaatcggtag atatgacgga gttcacacgc
    23281 cgtatggacc gtggtattta cgaccctgaa gagtttgaac gtgctatggt ttgggtaaaa
    23341 gaacatatca aagaaggagt tgaccgaaat cgtgaggatt tgattctttc taaagaagag
    23401 aaagaaaaac aatgggaatt tgttattaag atgttcatga ttggacgtga cttaatggtt
    23461 ggtaacccaa gacttgctga acttggtttt gaggaagaag cagttggtca ccatgcttta
    23521 gtagctggtt tccaaggtca acgtcagtgg acagaccatt ttccaaatgg agattttatg
    23581 gaaactttcc tcaatactca gtttgactgg aatggtattc gaaaaccatt tgtatttgcg
    23641 acagagaatg attcactaaa tggtgtgtct atgctcttta attatctatt aacaaatact
    23701 ccacaaatct ttgctgatgt gcgtacttat tggagcccag aggctgttaa acgtgtaacg
    23761 ggacatactt tagagggtcg tgctgcagct ggcttcttac atctaatcaa ctctggttct
    23821 tgtacattgg atggtacagg tcaagctact cgagatggca aacctgttat gaaaccattc
    23881 tgggagttgg aagaaagtga agtgcaggct atgcttgaaa atacagactt cccaccagca
    23941 aaccgcgaat acttccgtgg aggaggattc tcaactcgtt tcttgacgaa gggggatatg
    24001 ccggtaacaa tggtacgtct caatcttcta aaaggggttg gtccagtgct acaaattgca
    24061 gaaggttata cacttgaact tcctgaagat gttcaccata ctttagataa tcgtacagat
    24121 ccaggatggc caactacttg gtttgctcca cgtttgacag gaaaaggtgc tttcaagtct
    24181 gtctatgacg tcatgaataa ttggggagct aatcacggag ccataacata tggccacatt
    24241 ggagcagact tgattacctt ggcttctatg ttgagaattc ctgtcaatat gcataatgta
    24301 cctgaggaag atatctttag acctaaaaat tggtccttat ttggaacaga agatctagaa
    24361 tcagcagact atcgtgcatg tcagttgttg ggaccactac ataaataaaa cttgtttata
    24421 taggaggtga acttacgtcc ctcctatcct tttaaaaaga tttgttaaac aattcacaaa
    24481 taattgaaaa cgaatacaaa aagtaatata atgatgttaa atagatagcg caaaggcgca
    24541 ggaggaaaat tatatggcta cattttatgt tccggcagtc aaccttattg gtaaaggtgt
    24601 tgtaaatgaa gtgggtcctt atatcaagga acttggctat aaaaaggcac ttttggtgac
    24661 agataagtac atcgaaggca gtgacatttt acctaaggtt ttaaaaccac tggatacaga
    24721 aggaatcgaa tatgtcatct ttagcgatgt agagccaaac cctacttgta agaatgtcac
    24781 agatggggta gctgctttgc aagaacatgg atgtgatttt atcatcagtc ttggtggggg
    24841 ttctccacag gatgcagcta gttgtatttc tatcatggct acaaatggtg gaagaccaca
    24901 ggattatgaa gggcttcata agtctgctaa aaaaggcttg ccagttgtgg ctatcaatac
    24961 aacggcagga acttctgcag aaatcactat taactatgtg attactgatg aagaacgcaa
    25021 ggttaagatg gtaatggttg acaagaatag ccttgctctt atctctgtca atgacccgga
    25081 actcatgctt tccaaacctc aagccttgac tgctgctact ggtatggatg ctctgactca
    25141 cgctgttgaa gctttggtaa cacctggtgc ttatgatgta accaagaaac tgtctattgg
    25201 tgctattgag cttatcaagg aatatcttcc ttgtgctgta gaaaatggac atgatattga
    25261 agcgcgtgaa ggtatggtca atgccatctt ccttggtggt atgagcttta ataatgctgg
    25321 tcttggctat gttcactcaa tggctcacca actcggtgca gtatataatt tgccacatgg
    25381 cgtgtgctgt gccatgttgc taccagttat agaacgtgaa aatgctaaac gtgtaccaga
    25441 agctttccgc aatgttgcca aagccttggg acttcatgta gaaggtaaat cagatcaaga
    25501 atgtgccgat tatgcgattg ctgagattga gaagctttct gagacagtag gtattcctaa
    25561 gaaactgact gaacttggta ttgaagaaaa agatttcgac tttgaatacc tttctaagaa
    25621 tgccttgatt gatgcctgcg caccaggaaa tccatttatg ccaaccttag aagaaacgat
    25681 tgccttttat aaagagttat tttagcaaga gattagacga caataggaca attcacctct
    25741 aattattgac atttcaggaa aaatcgcagt aaaaacggca cagccttctt taaatgtgct
    25801 ataatactag aaaaatactt gtggaggttc cattatggca atatttttca tgatttttct
    25861 gattgtttgt gtgctcctat tggtgatagt cacactgagt acagtttatg tggttcgtca
    25921 gcagtcggtg gcgattattg aacgctttgg gaaataccaa aaggttgcta atagcggtat
    25981 tcatattcgc ttgccttttg ggattgactc gattgcagca cggattcagt tgcgcttgtt
    26041 gcaaagtgat attgtggttg agactaagac caaggacaat gtgttcgtta tgatgaatgt
    26101 agcgactcag taccgtgtca acgagcagag cgtgacagat gcttactata aactcatacg
    26161 tccagaatct cagattaaat cttatatcga agatgctctt cgctcttctg ttccaaaatt
    26221 aaccttggat gaattgtttg agaaaaaaga tgagattgcc cttgaagttc aacaccaagt
    26281 agcagaagaa atgaccactt acggctacat tatcgtgaaa accttgatta ccaaggtcga
    26341 accggatgca gaagttaagc aatccatgaa tgaaatcaat gcggcgcaac gtaagcgggt
    26401 cgcagcacaa gaattggcgg aagctgacaa gattaaaatt gtcactgcag ctgaagcaga
    26461 agcagaaaaa gaccgccttc atggtgtggg gattgcccaa caacgtaagg cgattgtgga
    26521 tggattggca gagtctatca ccgaactcaa ggaagccaat gttggcatga cagaagaaca
    26581 aatcatgtct atcctcttga ccaaccagta tttggatacc ttgaatacct ttgcctctaa
    26641 aggaaatcaa accatctttt taccaaatac gccaaatggt gtggatgata tccgaacaca
    26701 aatcttgtca gcccttcgcg ctgagaagaa ataatagact aatactcttc gaaaatctct
    26761 tcaaaccacg tcagcgtcgc cttgccgtat agatgttact gacttcgtca gttctatctg
    26821 caacctcaaa acagtgtttt gagctgactt cgtcagttct atccacaacc tcaaaacagt
    26881 gttttgagct gacttcgtca gtcttatcta ctacctcaaa acggtgtttt gagcaacctg
    26941 tggctagttt cctagtttac tatttgattt tcattgagta caaagagctt ggcaacaggc
    27001 tctttttgta ttgcgtttat taagaaaaac aaaaaacatc gatatacatt taactaaaaa
    27061 ttattgtatg ttatctccct taattaggaa tgataaggga ataactagaa agatttgtga
    27121 atacaaacta tttctgatat acaaaatata cagtaataat gaatgatggg agatgggatg
    27181 aaagaatttc aatttgagag aaagcagcgt ttttctttga ggaaatatgc aatgggagct
    27241 tgttcggtct tgctaggaac gagtttattt tttgctggta tgggtgctca gcctgtatag
    27301 gatacagaaa cgagttcagc actaatttca agtcattatt tggatgagca ggatttatct
    27361 gaaaagctga aatctgagtt gcaatggttt gaattagaaa acaagctttt gaacttatgg
    27421 gagcattagg ttactatgaa ggatttgttc cttatgtttc aaatcaatac aaaaaccaaa
    27481 ctgaagaaga aggcaaaccg ctatctgata aatatatttt cgaaaaaatc ttaggaaaaa
    27541 catatgcagc cttcaaaaaa gatcaaatta atgagcgtgt cgagaaatta ggtaagttaa
    27601 aacctattac aataaattac aacggaaaat cagaagtaat tgatagtaaa gaaaaattac
    27661 aaaagcttat gaataaagcc gttaaagacg aagtggctca aatatagtaa aatgaaataa
    27721 gaacaggaca aatcgatcag gacagtcaaa tcgatttcta aaaatgtttt agaaggagag
    27781 gtgtactatt ctagtttcaa tatactataa aatcaggcaa taccacggct aaaaagtttg
    27841 agtttatcga aacaccagtg caaaaactga aaaaagcgat ttataaagct catctcaaag
    27901 attcagatga ctttagacca gaaacatcca caccaaatct ttttgaaagc tgtttgaagc
    27961 tttgtccttg ctttcttagt tcatagatct gaactttatc ttcataactc aatttcataa
    28021 taaaacaccc caaaagttag atttattctg tctaactttt ggggtgcagt tcattaatcg
    28081 gtcgattttt ttggtagaaa cagttgcctg attaagttgc aagtcgatag acggcttcgg
    28141 cataaatatc catagcacgg tacaaatctt ctagaacggc acattcattt gcctgatgtt
    28201 ctgtctgctt cgctcctggg aataaggcgc cgaaggctac acaatttggc atggtgcgag
    28261 caaaagtggc accaccggat gaaatagcag gactgttatc gccagtcttt tcttggtaga
    28321 tttgcatcag tgtgctaacg agtttactgt cttttgcgac gtatagaggc gctagatagt
    28381 caaactcttc gtagcggagt tggtagtttt gtgcacatct tgtaagcaac tctactagtt
    28441 cttccttatc agctaagaca ggagtccgaa tgtcaatacg gatttcagaa cgttcatgat
    28501 tgatcatgag acctgcgaca ttaaaggata ggtgaccaga aggttcatct gctatatcac
    28561 caaagatttg tcttcctgtg ccgtcttgac ctgcttgtgt tgcaagaaaa ctgagagcag
    28621 ggtgttcttg gagaggagca agaatggtag ctagtcggat gacagcattg ataccttgac
    28681 tagcatcctt agcatgcttt ggcactccga gaaccgttac ggtttgttca gtggattggt
    28741 aatcataacc agcttctttg agaccgttac aaacctgttc atagagggga ccttggtagt
    28801 tggccttgtc tggtacaacg ttaaaggcgc ctcctacttc aagctctagt tgatccgatc
    28861 cagggccatg aagtttgacc tgtagaagcc ctttttcagc ataggtcaga ggaaaagatg
    28921 agtcaggtgc aaagcccatg ctggcctgtt cttcgatggt attgtagcgt gccatgcagc
    28981 gccagagggt ttcctcatcg gtaccaaaga taaagcgtac gcgctttttg aactgaatac
    29041 cttggtccag caagcttttt actgcataga gagctgcgag cgaagggcct ttatcatctt
    29101 ggacaccacg tccgaatacc cagccgtctt tgatagttgc ttcaaatggc ggtgtctgcc
    29161 aatctgcttc atcacctgat ggaacaacat ccaaatgaca gagaatggcc agaagctctg
    29221 ctccctgacc gatttctgca tatccgtaat aacctttagg gtcaagatag gtagtgaaac
    29281 ctatgtcttg acaaatctct aaagtttttt ctaggacatc ttggattgct tgtccaaaag
    29341 gtgttccatt ttctccttca ttgagtactg aaggatagga aatcaaggtt tttaatgata
    29401 taagaaattc atctttaact tgatttgtta tatctatttt catggaatca cctcactcac
    29461 tattttatag gaatggaagg aaggttccaa ggagaagaag ggcgatggtc actacaataa
    29521 tagcgactac gagtttgccc atgaatttcc accaagtacc aatgttgata cgtccaagtg
    29581 caagagctcc catcacaata ccagatgttg gtgcaatcaa gttcaagaca cctgaagcag
    29641 attggtaagc agtgataatc aagctaggac ggacatttac aaattctcca agtggagcca
    29701 tgatacccat agttgcgctg gcaagaccag atgaagatgg gatcaagaat gacataggta
    29761 gatagaagat ataagttaca acgataaaga cttgtgaaga tagaccgctc aagccttctt
    29821 taccccagtt gaggattgta tcggtaatca taccgtcgtt catgataact tgaataccac
    29881 gagcaatcgc tacgatcaag gcaacactga gcaaatcagc agcaccattc atgaaggaag
    29941 agataatctt atcttcttta agaccataaa taacaccaat caggataccc ataaaggcaa
    30001 agagcattgc gccttctggg aagtaccaag tacctagtgc agaagtagat gaaccgacaa
    30061 tattaccaat aactggaaga ccagtcaacc aagcattaaa gtcatcaaaa atggtaacgc
    30121 caaggtctgt ccatggaatg aagctcaata ccatcaagat gaatgtcaac acaaataaga
    30181 agagaactga tttttgtttg ctgctaagtg tagattctac agatgaagat tcttctacgt
    30241 taaagtgttt caaatcttct ttgcgagtac tataaaccag tgacttagtc ggatcttttt
    30301 gaatcttatc cgcataacgg taaacaaacc aagtactaag agcagtcaag gtaacccaga
    30361 agatcagacg aagtacgata ccgtcccctg taccaactcc cgcagtcgct gaagcaatac
    30421 ctgtcgcaaa tggattcaga gtagatgcca aacagccgat ttgagaaccg agcaaaataa
    30481 ttgcaacacc agtcaggcta tcaaaaccaa cggccatcat aactggcaca aggagtggat
    30541 agaaggccat tgtttcttcc cccataccat aagttgtacc accgagggca aacaaaggca
    30601 tcagtaccaa aattaacatt ttttcgcggc ccttatactt cttcacgata gaggcaatcc
    30661 ctacgtcaag agcaccagtt ttgttgacaa tgccaaggaa accaccaacc ataaggatga
    30721 agaaggctac atcaatcgct gcactcgttt ctttaatgag cgaaccttcc tctggatgag
    30781 tacctagcat agcccgaatc ggtgccatga ggacatccca aatcccttgt ggattttgag
    30841 gttgagcctc gtaaatacct tctataaagg cccccgcagg gataaaccaa gttagcacgg
    30901 ccataatagc aatgattatc aataatacgg tgtaagatga aggcatctta aacccttttt
    30961 tagctttttc actcatttgt ttttcctcct gatgtctaac aaagtgtaaa aaaccaacta
    31021 ctttcttaaa taaacattca agaaaacgct ttctatttat atttgtttta ccatattaaa
    31081 gtctaaaaaa ctaatatctt ttgaaatatt gtacatgttt tcaagaataa tttctaattt
    31141 gatataaaga tactagaaat agaatacatc ttattagtaa aacaacttat cctttttcaa
    31201 taattgttcc gctttcagat tcaatcaagg cgcctagatt ttcaagggaa gtaataactg
    31261 cttttccttc tggacgacca ttgacaaaag cgatagctgc ttctactttt ggaagcatgc
    31321 tacctggtgc aaactgatct tgtttgatat attcttccag ctgggcaaca ttcacatgtt
    31381 ccaatttttc ctggtttggc ttgttgtagt taacaaatac ataatctaca cctgtcaaaa
    31441 tgatgaagag gtctgcatca accaattctg ccaaacgttg ggaagcgaag tctttatcaa
    31501 taaccgcttc gacaccagtc aaatgtccat tgttttcttt gacgacggga ataccgccac
    31561 cacctgcagc tacgacgact tgaccattat ttaaaagagt acggatggtt tcaatttctt
    31621 tgatgtcaac aggttttggt gaggcaacga ccttacgcca gccacggcca gcatcttcct
    31681 tgaaagtcgc tccgcttttt tcggcttctg cttttgcttc ttcttctgaa tagaaaggac
    31741 cgattggttt actcaagtta acaaaagctg gatcattttt atctacgaca acttgcgtta
    31801 caacagaggc aacatttttt tcgatgcctt catccaagag agcattttgc aaagcatttt
    31861 tcaaccagaa accgatgcta ccttctgtca tagcgacaag tgagtcgagt gggaaggcag
    31921 ggttcttttc agagtctgat gccaaatgtt ggagcaagag attcccaact tgaggtccat
    31981 taccgtgagt gataatcaaa tcatctccat ttttaatcaa ttttacaaga tgcttagctg
    32041 tttcaactaa agcttcttgt tgagcctttg ctgatgggtc agaagaaaga atcgcatttc
    32101 ctcccaaagc tactacaatt ttacgatttg ccataaattc tcctttatca cactcaatag
    32161 aatgcgttta gatttcaatt taatgatttt tcacatattt tataagaaat aatagattac
    32221 cattacataa aagaggaccg gactaaagct attagtcgca gccctcatag ctgttggtag
    32281 acggtttatt atctaaaatt atactttagg aatataaagg ttaccaagtg tagcagccat
    32341 aacagctttg atagtgtgca tacggttttc tgcttgatcg aagtggcgag cgtacttgct
    32401 gcggaagact tcgtctgtta cttccatttc ttctacacca aatttttcag caacgtcttt
    32461 accataaaca gtgtgagtat cgtggaatgc tggcaagcag tgtaggaaga tcaagttttc
    32521 attgcctgct tttttaacta agtccatatt gacttggtaa ggtttaagaa gagctacacg
    32581 ttctgcgaat ttgtcttctt cacccattga tacccaaacg tctgtgtaaa gaacgtctgc
    32641 atctttaact gcttcatcag catcttcagt gatgagaaca tgtgcgccac tttctttagc
    32701 aaatccttct gccaattcaa cgatttcttt ttctgggaag agttcttttg gtgagaagat
    32761 gtgaacattg acaccaagga tagcacctgt tacgagcaag ctgttggcaa cgttgttacg
    32821 tccatcacca cagtatacca atgtcaagcc ttccaagcga ccgaagtttt cttgaacagt
    32881 caagtagtca gcgagcattt gagttgggtg ccattcgtca gttagaccgt tccatactgg
    32941 aacgcctgag aattctgcca attcttcaac catacgttgg ctgaatccgc ggaattcaat
    33001 cccgtcaaac atacgtccca atactttagc agtatcttca gtagattctt ttttacccaa
    33061 ctgaatatca tttgctccga ggtattctgg gtgagcacca aggtcgatag ccgcagttgt
    33121 aaaggctgca cgagtacgag tagatgtttt ttcaaatagg agagcgatat tcttgccagc
    33181 aaggtagtgg tgttgaatat tgcgtttttt caaatctttc aagtgagctg aaagaccaat
    33241 aaggtattct aactctgcac gggtaaagtc tttttctgct aagaagctgc gtccttggaa
    33301 tactgaattt gtcattttat tatttcctct ttctattttt tacattttct attgacgaat
    33361 accgaacagc gattacactt cttcacgttc aaatggcata gacatacaac gaggtccacc
    33421 acggccccga accaattcac ttccgcgaat cttaatcaag cgaagcccgt attcttccaa
    33481 aatcttattg gtcacggtat tgcggtcata aacaactacc acaccaggtg cgatggtcaa
    33541 agtgttagaa ccgtcgttcc attgttcacg cgcagctgct acgatattgc caccaccgca
    33601 acgaatcaaa tgaacttttt ctacaccaag gttttgagca agaagttcag ctaagtcacc
    33661 tttctcttca acgattttaa gtttttcgtt ttcgtaagta actgagtaaa cgtgaaggtc
    33721 gccttcgatt tctgggtgaa tagtgaactt gtcatagtct accatagtga agacagtatc
    33781 caagtgcatg aatttacggt tgttagcaaa ttcaaaggcc aaaactttct tgaagccaac
    33841 atttttcttg aagatgttga ccaaaagttt ttcgatagaa gctgcgtctg tacgttgaga
    33901 aatacctact gcaaggacgt ctttagaaag aactagctcg tctccacctt cgatacgcgt
    33961 atcttcttca cggttgtaga ccaaatccac ttttccgcca tagattgggt ggtatttgaa
    34021 gatatactta ccgtagagtg tttcacggtt acgagtgtct gcaaacatgt ggttaagcga
    34081 tacggcgttt ccaattgttg caaatgggtc gcgagtgaaa tagaggtttg gcatcgggtc
    34141 aattgcaaat ggataatctg attcaactaa gtcagttaga tctttagctt cgtcaggaat
    34201 ttctggcaat tcaacttttt gaatcccagc cattgttttt tcaaccaatt cttggttgtc
    34261 cttgatgccg tgaagcaatt cacgaatagc aaccttggtt tgacgatcac ggatgttggc
    34321 ttcgtctaag tattcctcga taaattgatc gcggatttct ggagaggtca atgattcagc
    34381 agcgagttgt tctaggtaga gaacctcaat tccttcatcg cgaagagctt gggcaaatgc
    34441 atcatgttct ttttgagcat cttccaagaa aggaatatca tcaaaaagaa gcctttcaag
    34501 atagtccggc aacaagtttt ctaactcctt gcctggacgg tgcaacataa cttttttcag
    34561 tttcccaatt tctgagaaga cctgaattgg atgtgaagac atgtattttc ctccttaaaa
    34621 attttgactt ggcaccattt tgggtaccgc ttacatgtat gttataacgc aattcctagg
    34681 taatgtcaat ggctataatt tctcggaaaa taatataaat tatgatattt agcacaattt
    34741 tatgttatta tacataacat aggatagaat acatagatac aaatgcataa acttctataa
    34801 aaaggatata aaattttttt aaaaaatttt tcaaaaaata tacaaatgac caaaaagtgt
    34861 ccaattatca tctggttatc acttggatct gtataaagag aaatgtttgt gtgaaaggat
    34921 aaaaagatgc aacattcttt tgaagataga ttttggagaa gcatttcttg ttcaattgta
    34981 caaattatag aatcttttct gagtatttag gaagagataa ttatcttatt gaccctcttt
    35041 ttattttttg ttatagtcga cgaggtgata gtttagaata atcacttatt cacaatctgt
    35101 ggaaaagtct ggagagtgaa tggtcttcac acaatgacct gaaagaagcc tgagaataat
    35161 tatggagagt agcattctga gaggtgttag cagaaccata tgacagagct gtttgaagag
    35221 ggaatattga ggagcaaaat cctgagccta ccagttggag ttggaaagag ctggctgtta
    35281 gatcatggtt tattatccac aacctgtgga taaccttgtg aacaagagaa gttgctaaag
    35341 aaggagatat ataacgatga agaaaatcaa accgcatgga ccgttaccaa gtcagactca
    35401 gctagcttat ctgggagatg aactagcagc ttttatccac ttcggtccta atacctttta
    35461 tgaccaagaa tgggggactg gacaggagga tcctgagcgc tttaacccga gtcagttgga
    35521 tgcgcgtgag tgggttcgtg tgctcaagga aacgggcttc aaaaagttga ttttggtggt
    35581 caagcaccac gatggctttg tcctttatcc gacagctcac acagattatt cggttaaggt
    35641 cagtccttgg aggagaggaa agggcgactt gctccttgaa gtatcccaag ctgccacaga
    35701 gtttgatatg gatatggggg tctacctgtc accgtgggat gcccatagtc ccctctatca
    35761 tgtggaccga gaagcggact acaatgccta ttatctggct cagctgaagg aaatcttatc
    35821 aaatcctgcc tatggaaatg gagggaaatt tgctgaggtt tggatggatg gtgccagagg
    35881 agagggcgcg caaaaggtta attatgaatt tgaaaaatgg tttgaaacca ttcgtgacct
    35941 gcagggcaat tgcttgattt tttcaacaga aggcaccagt atccgatgga ttggcaatga
    36001 acgagggtat gcaggtgatc cactgtggca aaaggtgaat cctgataaac taggaacaga
    36061 agcagagctg gactatcttc agcacgggga tccctcgggc acgatttttt caatcggaga
    36121 ggcagatgtt tccatccgtc caggctggtt ctaccatgag gatcaggatc ctaagtctct
    36181 cgaggagttg gtcgaaatct actttcactc agtagggcga ggaactccac tcttgcttaa
    36241 tattccgccg aatcaagctg ggctctttga tgcaaaggat attgaacgac tttatgaatt
    36301 tgcgacctat cgcaatgagc tctataaaga agatttggct ctgggagctg aggtatctgg
    36361 tccaactctt tccgcagact ttgcttgtcg ccatttgaca gacggccttg agaccagctc
    36421 ttgggcaagc gatgcagact tgcccatcca gttagaactc gacttaggtt ctcctaaaac
    36481 ttttgatgta attgagttaa gagaagattt gaagctaggg caacgaatcg ctgctttcca
    36541 tgtgcaagta gaggtggatg gtgtctggca ggaatttggc aggggcttca cagttggtca
    36601 taagcgcctc ttgcgaggtc cgctagtaga ggcacagaag atacgtgtag tcattacaga
    36661 atcacaggct ttgcctttgt tgaccaagat ttccctttat aaaactcctg gattatcaaa
    36721 aaaagaagtt gttcaggaac tagcatttgc agaaaaaagc ctagctgtgg caaagggaga
    36781 gactcttcat tttaggattg aacgtagtga aagtagctcc tctttagagg ctaagatttc
    36841 gattcaaccg gggacaggtg tccatggtgt cgcctatcag gatgagattc aagtccttca
    36901 attccaagca ggggaaagca aaaaagattt gcatctacca accctgtatt tcgcaggaga
    36961 taaaaccttg gatttctatc tgaacctaac ggtggatggt cagcttgtgg atcaacttca
    37021 agtccaagtt tcataaaaga agaacctttg cgcgatgcaa aggttctttt ggttattaat
    37081 gacttggtaa ccagctgagg gtgaaagtta gttgttcagc ttttaagagg tcttggtgtt
    37141 gaatagttga tacgagtgtt ttgtccagtc ggcattcttt gacaaagtta aaatggttgt
    37201 ggttttgttt agtatggata tccagccatt tatcttcttt agcgaggtag actcgtagat
    37261 ggtcaaagag agggattccg aggtcatagc ttggttttcc tggacaggtt ggataaaatc
    37321 cgagagctga ccagatgtac caagcagaga gactaccatt gtcttcatct ccaggatagg
    37381 cttcccaact tgggtgaaaa gctttctgac ggagcgtctt gataagaagg gcagtgtagt
    37441 cagggtaatc gctgtagcgg aagagataag gaatgtggaa actaggctgg ttggaaatgg
    37501 ctatttgtcc aaaaggagca gtagccatct cgctcatttc gtgaatttca taaccatagc
    37561 ctgttgtttc aaagagggga gcatcttgac aggctttcaa aagatagttg ctaaaggttt
    37621 cttttccacc catcagttgg attaagccag ggatgtcgtg gagaacgcct aaagtagctt
    37681 gaatggcaga gcattcagcg tagtctcgcc cccaactata aggagagaag tcagggtgaa
    37741 agtttccttg attgtctcgt gctcgcatgt aacctgtctc agcgtcaaat agctggcggt
    37801 aattttgtga agcagccttg taggtttcag cgatttctat gttctctagt tttttggcac
    37861 agctggcgat acaaaagtca ctataggcat agtctagagt atggctaaca ctttcgtggt
    37921 ggtcggtaga gaggtaacct agttcttggt attgggctag tccgtggcgg ccattgatgc
    37981 cgagagggtc ggctttgctg gctgtttcga gcatggcttg gaagagttct ccttctaggt
    38041 caggggccat gtccttgcag gcgctatctg cgataatacc gtctaaaagt gtacctggca
    38101 tcataccccg ttcatctgga gccagccatt ttggaaggaa accagtatcg cggtagctat
    38161 tgaggaaacc ttctaaaaag cgttgatagt gctccggtat gataagggca aagaggggga
    38221 aggtggtgcg gaaggtatcc cagaaaccat tgttgctaaa gaggacacca ggcttgacag
    38281 taccagtagc cagatccatg tggatggctt gccctgactc atcaacctca taaaaagtct
    38341 gtgggaagag gaagagtctg tagagacagt ggtcaaagaa ggttcggtca gcctctcctg
    38401 tctctataat gtcaaaacga tggaggagat tttcccaatc cgcttgggca cttgctttac
    38461 agctatcaaa atcttcttga ggtagattga ttagagcttg agaaggagag atgaaagaag
    38521 tggctagttg catctcggtt tgactacttg ctaagtcaat tcgccagtct cccccttctt
    38581 ggctgatagc aagaatatcc gtgttcattt gcagggcagt gaacatcgtt agcgaatttt
    38641 tgttagtttc agttttacct tcttgtcgca gggcaagagt ccgcttatct acttgctcta
    38701 cggtcagttc atctgctgcg tgaagataga gggagagggc tttgccttgc ttttgattca
    38761 aacgaataga agcaccatag caagtcggtg tgagctgggt ttcaatctga taacgcagag
    38821 aaaagagctt caaatagtga ggctggaagc aagctttatc tatatcataa gaagactggc
    38881 ggtgaaagag gctgtctcca cccagttgac tggtgacagg tgtcagaagg agccaagagt
    38941 agtccccaat ccaaggactg ggctggtgag ttaatcgaat cccctgaaag ataggcagat
    39001 gcggatcaaa aaaccaagat ccatcctggt cactggtctg gggcacaaag taattcattc
    39061 caagaggcac gcctgtgtat ggcagggtat ttccccgaga gaaggcatgc ttgctagcag
    39121 taccaaagcg ggtatcgatg gtttcaagta gtggtttcat agtctttcct ttagctgttt
    39181 ttctacatta tatcagaaaa agagggcctt tagaaaagga gtttcaaaaa taactatttt
    39241 gtagaaaaat gactatcatt tgtgtatgta ttttctgtct caaaagctat atactgaaaa
    39301 tgaaacttgt ttgaaagagg aaattgcacg atgatttatt cgaaagaaat tgttagagaa
    39361 tggctagatg aagtagcaga gcgggctaag gaccatccag agtgggtgga tgttttcgag
    39421 cgttgctaca ccgatacctt ggacaatacg gttgaaatct tagaagatgg ttcaactttt
    39481 gtcttgactg gggatattcc tgctatgtgg cttcgggatt cgacagccca actcagaccc
    39541 taccttcatg tagctaaaag agatgccctc ctgcgtcaga ccattgcagg tttggtcaaa
    39601 cgtcagatga ccttggtact caaggatcct tatgccaatt ccttcaacat agaggaaaac
    39661 tggaaggggc accacgagac cgaccacacc gaccttaatg gctggatttg ggaacgcaag
    39721 tatgaggtgg actcgctttg ctatcctttg cagttgtctt atctcctctg gaaagaaact
    39781 ggcgagacta gtcagtttga tgagactttt gtcgcagcga ctaaggaaat tcttcatctg
    39841 tggacggtag aacaagatca taagaactct ccttatcgtt ttgtccgaga tacggaccgc
    39901 aaggaagaca ccttggtaaa tgatggcttt ggacctgatt ttgcagtgac aggtatgact
    39961 tggtcagcct ttcgtccgag tgatgactgt tgccagtata gttacttgat tccgtcaaat
    40021 atgtttgctg tagtagtctt gggttatgtg caagaaatct tcgcagcatt aaacctagct
    40081 gatagccaga gtgttattgc tgatgccaag cgtcttcagg atgaaatcca agaaggaatc
    40141 gaaaactacg cctacacaag caacagcaag ggtgaaaaga tttatgcctt tgaagtggat
    40201 ggtctaggaa atgccagcat catggatgat ccaaatgtac caagtctact agctgcgccc
    40261 tatctgggct actgttcggt cgatgatgaa gtgtatcaag ctactcgtcg taccattttg
    40321 agctctgaaa atccatattt ctaccaagga gaatacgcta gcggtctcgg aagttctcat
    40381 accttctatc gctatatctg gccaatcgcc ctttctatcc aaggattgac aacaagagat
    40441 aaggcagaga aaaaattctt gctggatcag ctggttgcct gcgatggtgg tacaggtgtc
    40501 atgcacgaaa gcttccacgt agatgatccg accctctact ctcgtgaatg gttctcctgg
    40561 gctaacatga tgttctgtga gttggtcttg gattacttgg atattcgcta aggggctcgc
    40621 tttagctcaa ccgattctta tcagaatcac aagtttacat ttaaaacgtt aaaatttaaa
    40681 tttagaatga ggttttactt catggaaaat gttgttgtac atattatctc acatagtcac
    40741 tgggaccgtg agtggtactt gccttttgaa agccatcgta tgcagttggt ggaattgttt
    40801 gacaatctct ttgatctctt tgaaaatgac cctgagttca agagtttcca cttggatgga
    40861 caaactattg tccttgatga ctacttacaa attcgccctg aaaatcgtga caaggtccaa
    40921 cgctacattg acgagggcaa acttaaaatt ggtccctttt acatcttgca ggatgactac
    40981 ttgatctcca gtgaagccaa tgtccgcaat accttgattg gtcaacaaga agctgccaaa
    41041 tggggtaaat caacccagat tggctacttt ccagatacct ttggaaatat gggacaagcg
    41101 cctcaaattc ttcaaaaatc aggcattcac gtggcggcct ttggtcgtgg tgtgaagccg
    41161 attggatttg acaaccaagt ccttgaagat gagcagttta catcccagtt ttcagaaatg
    41221 tactggcagg gtgtggatgg tagtcgtgtt ttaggtattc tctttgccaa ctggtacagt
    41281 aatgggaatg aaatcccagt tgacaaagat gaggccttga ccttctggaa acaaaaattg
    41341 tcagatgtgc gtgcctacgc ttcgaccaac caatggttga tgatgaacgg ctgtgaccac
    41401 cagcctgtcc agaaaaatct gagcgaagcc attcgtgtgg caaatgaact cttcccggat
    41461 gtaatctttg ttcatagttc ttttgatgaa tatgttcaag ctgtagaagg tgcgcttcct
    41521 gaacacttat caactgttac aggtgagttg accagtcagg aaacagatgg ctggtacaca
    41581 cttgccaaca cttcttcatc ccgcatttac ctaaaacaag ccttccaaga aaatagcaac
    41641 ctcctagagc aagtggtaga acccttgact attatcactg gtggacacaa ccacaaggac
    41701 cagttgacct atgcttggaa aacacttttg cagaatgcgc cacatgatag tatctgtggc
    41761 tgtagcgtgg acgaagttca ccgcgagatg gaaacgcgtt ttgccaaggt caaccaagta
    41821 ggaaactttg ttaaaagtaa tttgctcaac gagtggaagg gtaaaattgc tacggataag
    41881 gctcaaagtg actatctctt tactgtcatt aacacaggct tgcatgataa ggtcgatact
    41941 gtcagcacag tgattgatgt ggcgacttgt gatttcaagg aattgcaccc aacagaaggc
    42001 tacaaaaaga tggctgctct tatcttgcca agttaccgtg tggaggactt ggatggtcgt
    42061 cctgtagagg ctacaatcga agacctcgga gctaattttg agtatgattt accaaaagac
    42121 aagttccgcc aagctcgtat tgctcgtcaa gtgcgcgtga ccattccagt tcacctagcg
    42181 ccgctttctt ggacaacctt ccaattgctg gaaggaaaac aagaacaccg tgagggtatt
    42241 taccaaaacg gagtgattga tacaccattc gtaacggtga gtgtggatga caacatcaca
    42301 gtctatgaca agacaactca cgaagcctat gaagacttta tccgctttga agaccgtggg
    42361 gacatcggaa acgagtatat ctatttccaa ccaaaaggaa cagagccaat ctttgcagag
    42421 cttaagggcc acgaggtctt ggaaaacaca gcttgctatg ctaaaatctt gctcaaacat
    42481 gaattgaccg tgcctgtcag tgcggatgaa aagctagaag aagagcaaca aggtatcatc
    42541 gagtttatga agcgtgaggc tggacggtca gaagaattga caaacattcc tctggaaact
    42601 gagttgactg tcttcgttga caatccacaa atccgcttca agactcgctt tactaacact
    42661 gccaaggatc accgtatccg tctcttggtc aagactcata acacgcgtcc aagcaatgat
    42721 tctgaaagca tctatgaggt ggtgacacga ccaaacaaac cagcagcttc atgggaaaat
    42781 cctgaaaatc ctcaacacca acaagctttt gtcagtctgt atgacgatga aaaaggggtg
    42841 actgtatcca ataagggatt gaatgaatac gaaatccttg gggataacac cattgccgtg
    42901 accattttgc gtgcatcagg tgagctaggt gactggggct acttcccaac gccagaagca
    42961 caatgcttgc gtgagtttga agtcgaattt gcgattgaat gccaccaagc ccaagaacgc
    43021 ttctcagcct atcgtcgtgc caaagccttg cagacaccgt ttaccagcct tcagcttgct
    43081 agacaggaag gaagcgtggt tgcgactggt agcctcttga gccattctgt tctcagcata
    43141 ccgcaagttt gtccaacagc ctttaaagtg gcggaaaatg aagaaggcta tgtcctccgt
    43201 tactataata tgagtcaaga aaatgtgcgc atatcagaac atcaacaaac cattcttgac
    43261 ttacttgagc gaccatatcc agttcattca ggactattgg ctccacaaga gattcgtaca
    43321 gaattcatca aaaaagaaga aatttaattt caaaaagtaa acatcaaaag aaaggagggg
    43381 cgaaaaggta agaactaact actgattcgc ccctttttat ggtaaaaaca atgaccattg
    43441 caacgattga tatcggaggg actgggatta agtttgccag tctgactcct gatgggaaaa
    43501 tactggataa gacaagtatt tcaacgcctg aaaacttgga ggatttacta acgtggctag
    43561 atcaacgctt gtcagaacag gattacagtg ggattgctat gagcgttcca ggtgcggtca
    43621 atcaagagac aggtgtgatt gatggcttca gtgcggtgcc ctatatccat ggcttttctt
    43681 ggtatgaggc gcttagctct tatcagctac ctgtccattt agaaaatgat gccaactgcg
    43741 ttggactcag tgaactacta gctcatccag agcttgaaaa tgcagcctgt gtcgtgattg
    43801 ggacagggat tggcggagcc atgattatca atggtagact tcatcgaggt cgccacggtc
    43861 tgggtggaga atttggctac atgacaaccc ttgcccctgc tgaaaaactt aataactggt
    43921 cgcaactagc atcaactggg aatatggtac gatacgtgat tgaaaaatct ggtcatactg
    43981 attgggacgg tcgcaagatt taccaagagg ccgcagctgg taatgctctt tgtcaagaag
    44041 ccattgagcg catgaaccgc aatctgacgc aaggcttgct caatatccag tatctcatcg
    44101 atccagatgt catcagtctg ggtggctcta tcagtcaaaa tccagatttt atccaaggtg
    44161 ttaagaaggc tgttgaagac tttgtcgatg cctacgaaga atacacggtc gcaccagtta
    44221 tccaggcctg cacctatcac gcagatgcca atctctacgg tgcccttgtc aactggctac
    44281 aggaggaaaa gcaatggtaa gatttacagg acttagtccc aaacaaacgc aagctattga
    44341 ggttttaaaa ggtcacattt ctctaccaga tgtggaagtg gctgtcactc agtctgacca
    44401 agcctctatc tctatccagg gtgaggaagg tcactatcaa ttgacctacc gcaaacctca
    44461 ccaactttat cgtgccttgt ccttgttggt aacagttcta gcagaagctg ataaagtaga
    44521 gattgaggaa caagcagctt acgaagattt ggcttacatg gttgactgtt ctcgaaatgc
    44581 ggtgctgaat gtggcttctg ccaagcagat gattgaggtc ttggctctca tgggctactc
    44641 aacctttgag ctttacatgg aagacactta ccagattgaa ggacagcctt actttggcta
    44701 tttccgtgga gcttattcag cagaggagtt gcaggaaata gaagcctatg ctcaacagtt
    44761 tgacatgacc tttgtaccat gcatccagac cttggcccac ttgtcggcct ttgtcaaatg
    44821 gggtgtcaag gaagtgcagg agctccgtga tgtagaggac attcttctca ttggcgaaga
    44881 aaaggtttat gacctgattg atggcatgtt tgccacgttg tctaaactga agactcgcaa
    44941 ggtcaatatc gggatggacg aagcccactt ggttggtttg ggacgctacc tgattttgaa
    45001 cggtgttgtg gatcgtagtc tcctcatgtg ccaacacttg gagcgcgtgc tggatattgc
    45061 tgacaaatat ggtttccact gccagatgtg gagtgatatg ttcttcaaac tcatgtcagc
    45121 ggatggccag tacgatcgtg atgtggaaat tccagaggaa actcgtgtct acctagaccg
    45181 tctcaaagac cgtgtgactc tggtttactg ggattattat caggatagcg aggaaaaata
    45241 caaccgtaat ttccgcaatc atcacaagat tagccatgac cttgcatttg cagggggagc
    45301 ttggaagtgg attggcttta cacctcacaa ccattttagc cgtctagtgg ctatcgaggc
    45361 taataaagcc tgccgtgcca atcagattaa agaagtcatc gtaacgggtt ggggagacaa
    45421 tggtggtgaa actgcccagt tctctatcct accaagcttg caaatctggg cagaactcag
    45481 ctatcgcaat gacctagatg gtttgtctgc gcacttcaag accaatactg gtctaacggt
    45541 tgaggatttt atgcagattg accttgccaa cctcttacca gacctaccag gcaatctcag
    45601 cggtatcaat cccaaccgct atgtttttta tcaggatatt ctttgtccga ttcttgatca
    45661 acacatgaca cctgaacagg acaaaccgca cttcgctcag gctgctgaga cgcttgctaa
    45721 cattaaagaa aaagctggaa actatgccta tctctttgaa actcaggccc agttgaatgc
    45781 tattttaagt agcaaagtag atgtgggacg acgcattcgt caggcctacc aagcggatga
    45841 taaagaaagt ttacaacaaa tcgccagaca agaattacca gaacttagaa gccaaattga
    45901 agacttccat gccctcttta gtcaccaatg gctgaaagaa aacaaggtct ttggtttgga
    45961 tacagttgac atccgtatgg gcggactctt gcaacgcatc aaacgagcag aaagccgtat
    46021 cgagttttat ctggctggtc agcttgaccg catcgacgag ctggaagttg aaatcctacc
    46081 atttactgac ttctacgcag acaaggattt cgcagcaact acagccaacc agtggcatac
    46141 cattgcgaca gcgtcgacga tttatacgac tt
//
LOCUS       DAVHBD010000013        45513 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000013 DAVHBD010000000
VERSION     DAVHBD010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45513
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.013"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..259
                     /locus_tag="VVK04_000740"
     CDS             <1..259
                     /locus_tag="VVK04_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3989427.1"
                     /translation="DSGYQGLMKIYPQAQTPRKSSKLKPLTAEDQAYNHALSKERSKV
                     ENIFAKVKTFKMISTTYRNHRKRFGLRMNLIVGIINHELGF"
     gene            327..575
                     /locus_tag="VVK04_000741"
     CDS             327..575
                     /locus_tag="VVK04_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989428.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            706..1878
                     /locus_tag="VVK04_000742"
     CDS             706..1878
                     /locus_tag="VVK04_000742"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU3989429.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIVLYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1878..3152
                     /locus_tag="VVK04_000743"
     CDS             1878..3152
                     /locus_tag="VVK04_000743"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU3989430.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3187..4152)
                     /locus_tag="VVK04_000744"
     CDS             complement(3187..4152)
                     /locus_tag="VVK04_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU3989431.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4133..5587)
                     /locus_tag="VVK04_000745"
     CDS             complement(4133..5587)
                     /locus_tag="VVK04_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU3989432.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5964..7847
                     /locus_tag="VVK04_000746"
     CDS             5964..7847
                     /locus_tag="VVK04_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU3989433.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            7996..8883
                     /locus_tag="VVK04_000747"
     CDS             7996..8883
                     /locus_tag="VVK04_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU3989434.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(9203..9820)
                     /locus_tag="VVK04_000748"
     CDS             complement(9203..9820)
                     /locus_tag="VVK04_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU3989435.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10235..10423)
                     /locus_tag="VVK04_000749"
                     /pseudo
     CDS             complement(10235..10423)
                     /locus_tag="VVK04_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10933..11013)
                     /locus_tag="VVK04_000750"
                     /pseudo
     CDS             complement(10933..11013)
                     /locus_tag="VVK04_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11130..12023
                     /locus_tag="VVK04_000751"
     CDS             11130..12023
                     /locus_tag="VVK04_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989436.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            12020..13219
                     /locus_tag="VVK04_000752"
     CDS             12020..13219
                     /locus_tag="VVK04_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989437.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGSFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13572..14339)
                     /locus_tag="VVK04_000753"
     CDS             complement(13572..14339)
                     /locus_tag="VVK04_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989438.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14356..15051)
                     /locus_tag="VVK04_000754"
     CDS             complement(14356..15051)
                     /locus_tag="VVK04_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989439.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(15056..15421)
                     /locus_tag="VVK04_000755"
     CDS             complement(15056..15421)
                     /locus_tag="VVK04_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU3989440.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            15561..16034
                     /gene="nrdR"
                     /locus_tag="VVK04_000756"
     CDS             15561..16034
                     /gene="nrdR"
                     /locus_tag="VVK04_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU3989441.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            16035..17204
                     /locus_tag="VVK04_000757"
     CDS             16035..17204
                     /locus_tag="VVK04_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU3989442.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            17205..18101
                     /gene="dnaI"
                     /locus_tag="VVK04_000758"
     CDS             17205..18101
                     /gene="dnaI"
                     /locus_tag="VVK04_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU3989443.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            18098..18811
                     /locus_tag="VVK04_000759"
     CDS             18098..18811
                     /locus_tag="VVK04_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU3989444.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKPRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18825..20135
                     /gene="der"
                     /locus_tag="VVK04_000760"
     CDS             18825..20135
                     /gene="der"
                     /locus_tag="VVK04_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU3989445.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            20223..20558
                     /locus_tag="VVK04_000761"
     CDS             20223..20558
                     /locus_tag="VVK04_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989446.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20698..21033
                     /locus_tag="VVK04_000762"
     CDS             20698..21033
                     /locus_tag="VVK04_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989447.1"
                     /translation="MEHLFKMVILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGGRH"
     gene            21218..22009
                     /locus_tag="VVK04_000763"
     CDS             21218..22009
                     /locus_tag="VVK04_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989448.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            22002..22643
                     /locus_tag="VVK04_000764"
     CDS             22002..22643
                     /locus_tag="VVK04_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989449.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22647..23279
                     /locus_tag="VVK04_000765"
     CDS             22647..23279
                     /locus_tag="VVK04_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3989450.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            23307..23594
                     /locus_tag="VVK04_000766"
     CDS             23307..23594
                     /locus_tag="VVK04_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989451.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDKPLLGIRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23740..26253
                     /gene="secA"
                     /locus_tag="VVK04_000767"
     CDS             23740..26253
                     /gene="secA"
                     /locus_tag="VVK04_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU3989452.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26334..27365
                     /locus_tag="VVK04_000768"
     CDS             26334..27365
                     /locus_tag="VVK04_000768"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU3989453.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27367..28398
                     /locus_tag="VVK04_000769"
     CDS             27367..28398
                     /locus_tag="VVK04_000769"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU3989454.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28437..28805
                     /locus_tag="VVK04_000770"
     CDS             28437..28805
                     /locus_tag="VVK04_000770"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU3989455.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28795..29898
                     /locus_tag="VVK04_000771"
     CDS             28795..29898
                     /locus_tag="VVK04_000771"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU3989456.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29917..31932
                     /gene="recG"
                     /locus_tag="VVK04_000772"
     CDS             29917..31932
                     /gene="recG"
                     /locus_tag="VVK04_000772"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU3989457.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVVKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIETWQEDPEWRMIALHLEKKEHLD"
     gene            32249..33229
                     /locus_tag="VVK04_000773"
     CDS             32249..33229
                     /locus_tag="VVK04_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU3989458.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKKGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            34079..34306
                     /locus_tag="VVK04_000774"
     CDS             34079..34306
                     /locus_tag="VVK04_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989459.1"
                     /translation="MIFKVFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34594..37491
                     /gene="nanA"
                     /locus_tag="VVK04_000775"
     CDS             34594..37491
                     /gene="nanA"
                     /locus_tag="VVK04_000775"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU3989460.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNDQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLIAFFLGLFTLGKKREQ"
     gene            38507..38959
                     /locus_tag="VVK04_000776"
     CDS             38507..38959
                     /locus_tag="VVK04_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU3989461.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            38978..40315
                     /locus_tag="VVK04_000777"
     CDS             38978..40315
                     /locus_tag="VVK04_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU3989462.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            40394..41278
                     /locus_tag="VVK04_000778"
     CDS             40394..41278
                     /locus_tag="VVK04_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU3989463.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            41278..42111
                     /locus_tag="VVK04_000779"
     CDS             41278..42111
                     /locus_tag="VVK04_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU3989464.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            42129..44222
                     /gene="nanB"
                     /locus_tag="VVK04_000780"
     CDS             42129..44222
                     /gene="nanB"
                     /locus_tag="VVK04_000780"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU3989465.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYINGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            44234..45337
                     /locus_tag="VVK04_000781"
     CDS             44234..45337
                     /locus_tag="VVK04_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU3989466.1"
                     /translation="MVKYGVVGTGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
BASE COUNT        13897 a         8253 c         9976 g        13387 t
ORIGIN      
        1 tgacagtggt tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc
       61 cagcaaactc aagccgctaa cagctgaaga tcaagcctat aaccatgcgc tatccaagga
      121 gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatga tttcaacaac
      181 ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgttg gtattatcaa
      241 tcatgaacta ggattctagt tttgcaggaa gtctactatt ttccttattg tctgtaagtc
      301 tactgacctt gttgtttatc ccagtcatgg tttctagttc gggctcagag tttcaaagtg
      361 gatggcaaga gcatcaattg attgctgaga aggttagtaa aacacttgac aagacatttg
      421 ataaggatgt cagagaaatt ccgaccagtc agttttatca aaaatttgta gatgagatgg
      481 gaaggactta ctcaggaaat ttgatcctcc aggagctgat aactgtgaat ggagcttata
      541 aagctactta tatcggtgaa ctctctagca actaatcatt ctttaaaatg atgaccaata
      601 agaggcttga tttggtgaat caagtctttt ttctctcttt tactgccatt tgtgataaaa
      661 tagtatagaa cgatttttta catgaatgat aaaacagagg taaatatgac aatcggtatt
      721 gataagattg gttttgcgac cagtcaatat gtcttgaaat tacaagactt agcagaagcg
      781 aggggaattg accctgaaaa attaagtaaa ggactcttac tcaaggaatt gagtattgcg
      841 cccctaactg aggacatcgt gaccttggcg gccagtgcta gtgattctat tttaactgag
      901 caagaaagac aagaagttga catggtcatt gtggctaccg agtcaggaat tgaccagagt
      961 aaggctgcgg ccgtctttgt gcatggcttg ctgggcatcc agccctttgc tcgtagtttc
     1021 gagattaaag aagcctgcta tggggcgaca gctgccctcc attatgccaa attgcatgtg
     1081 gaaaattctc cggagtccaa ggtcttggtc attgccagtg atattgccaa atatggtatt
     1141 gaaactccgg gagaacccac tcagggtgct ggaagtgtag ctatgttgat tacacaaaat
     1201 ccacgcatga tggcctttaa taatgacaat gtagctcaga cccgtgacat catggatttc
     1261 tggcgaccaa attactcgac aactccttat gtaaatggtg tctattctac ccaacaatac
     1321 ttggatagtt tgaaaacgac ttggcttgaa tatcaaaaac gctaccagct tactttggat
     1381 gattttgcgg ctgtttgttt ccacttgcct tatcctaaat tagcgctaaa aggcttgaaa
     1441 aaaatcatgg ataagagcct gcctcaagag aaaaaagacc tcttacaaaa gcattttgac
     1501 cagtctattc tctacagtca aaaggtgggg aatatctaca caggttcact tttccttgga
     1561 cttttgtctc tcttggaaaa tacagatagc ttgaaagctg gggataaaat cgtcctttat
     1621 agttacggaa gtggagctgt ggctgagttc ttcagtggtg aattggttga aggatatgaa
     1681 gcttatttgg ataaagaccg cttgaacaag ctcaaccaac gaactgccct atccgttgca
     1741 gactatgaaa aggtcttttt tgaggaagta aacttggatg aaacaaactc tgcccagttt
     1801 gctggctatg aaaatcaaga ttttgccttg gttgaaattc ttgaccacca acgccgttat
     1861 agcaaggttg aaaaataatg aagataagtt ggaatggatt ttctaaaaaa tcataccaag
     1921 agcgcctcga gctgctaaaa gctcaggcgc tccttagtcc tgagagacaa gctagtctgg
     1981 agaaggatga acagatgagt gtgactgtgg cagaccagct gagtgagaat gtggtgggaa
     2041 ctttttctct gccttattcg ctggttccgg aggtacttgt caacggtcag gaatacaccg
     2101 ttccctatgt gacagaagaa ccctctgtgg ttgcggcggc cagctatgcc agcaaaatca
     2161 tcaagcgtgc aggtggtttt actgcacaag tccatcagcg ccagatgatt gggcaggtag
     2221 ccctttatca agttgctaat cctaaactag cgcaagagaa gattgccagc aagaaagcgg
     2281 agctcttgga gcttgccaat caagcctatc cttctatcgt taaacgtgga ggtggggcgc
     2341 gtgatctgca tgtcgagcag ataaaaggcg aaccagactt tctcgttgtt tatattcatg
     2401 tcgataccca ggaagccatg ggtgccaata tgctcaacac catgctggaa gccttgaaac
     2461 cagtcttaga agaactcagt cagggacaga gtctcatggg aatcctgtcc aactacgcga
     2521 ccgattctct ggtgactgca agctgtcgca tcgcctttcg ctacttgagc cgccaaaagg
     2581 atcaaggacg agagattgcg gagaaaattg cattggctag tcagtttgcg caggctgatc
     2641 cttaccgagc tgctactcat aataaaggaa tttttaatgg tattgatgcg attttgattg
     2701 ccactggtaa tgactggcgt gccatcgaag ctggggccca tgcctttgcc agtcgagatg
     2761 gacgttatca aggtcttagt tgctggacgc tggaccttga aagagaagaa ttggtcggtg
     2821 agatgaccct gcccatgcct gtagcgacta agggtggctc tatcggcctc aacccacgtg
     2881 tagctctcag tcatgatcta ctaggaaatc cttctgccag agaattagcc cagattatcg
     2941 tgtccatcgg tcttgcccaa aattttgcag ccctcaaagc cttggtaagt acgggcatcc
     3001 agcaaggcca catgaaacta caggccaaat ccctagctct cctagctggg gctagtgaat
     3061 ctgaagttgc tcccctagta gagcgcctca tctcagataa aacctttaac ctagagacag
     3121 cccagcgcta tctcgaaaat ttaagatcat aaaaactcag acgaatcggt ctgagttttc
     3181 ttgtgtttaa atactttttc ctggtaatag cgtaactggt aagaagtaac cagttgtggc
     3241 gacttccttg ccttcaatct tttgcaagag aagatcaata gtgagacaag caatctcttc
     3301 caaaggttgc ttgatagtag ccaattgagg gtagtaattt tcgataaagt aggtcccatc
     3361 atagccgatg accttgagct cttttgggac agaaatgccc aattcttgag cgattttaat
     3421 gaccagaata gctgtcaaat catccgaagc aaaaatggca tctggttttt cccgggtcaa
     3481 gatattcttg atttccattt cttttctgac gggagaaaag tcactggaaa cattgataat
     3541 aggagctttt gggagtacgg atgcaaaacc agcgtggcgc agtccggttg gcgaattgga
     3601 attgtcattc cctgtaatca tgatgataga ctgggcacct gtcttgacca aggtttgggc
     3661 agcaagaacc ccaccagcat agttgtcaga ggagacaaca gggatgtctg gcgataggtt
     3721 tcggtcaaag gaaataatcg gcgctgtcac acgattgtag tcttcgattc ctaggttgtg
     3781 actaccagaa atgatgccgt ctacctgatt ggcttccaac atttcgatgt attcgcgttc
     3841 cttctcagaa tcatgttcac tgttgcagat gatggtcttg taaccatttt tgaagagttg
     3901 gtgttccaat ttatcaatca attctgcata gaaaacattg gaaatattgg ggaaaatcaa
     3961 gccgattaac ttagctgatt ttccttgcag actacgagcc aggttgttgg gtttatagcc
     4021 taattctctc atggcttcat tgactttttg gatggttttc tcagatagat atcctttttt
     4081 attgataacc cgagaaacgg tagtaggact gacgcctgca agtttggcga catcagttag
     4141 ttttgcgacc ataatctaat tcatagtaag ttccagttgg gtttccagat ttgatcagga
     4201 taccattttg gtccgcatgt gggaagacac gaccagaaaa tactttttct cctttattga
     4261 tgaaaatttc aaagacagag ttatcgatga agattgtagc agtagtagcc tgattctcga
     4321 tagggcaaga acgagttgtc ccaaattctt gggcatactg ttctccagcc tggctacgat
     4381 ccactgtcac ttgaccgttt acaaggtcaa agttgattga aagtccctta ccttctttat
     4441 cagcaagtaa gacaatctcg ctctggctat tagcttccaa gttgagttca agttcgtaag
     4501 tgttcttggt ttgggaacgg tttgagaagg cttcttcaga agcacgaagg tccttaatag
     4561 cagcgactgg atactggtag agcttgtcgt ctttgatagt gagttccttg accaaagaga
     4621 aggttccttg gtggtcaaaa cggtcagatg ggtaagaaac atctggcaaa ccaagccagc
     4681 taactgctag agcacgccca tcaggagcgt tgaaggcttg agttgcatag gcttcgaaac
     4741 cgtaatccat gttttgaagt tgagacacat ctaccatttt ggcattttta gggtcaaagg
     4801 aagccccaat cttatacata tttggaaaga tattatcgta gtctagaact ttcttatcca
     4861 atccttgtgg acagtagaga aggacaggat gttcctctac aaagaccaga ttaggacatt
     4921 ccatcatgta ggcagtacgg tcgttagcaa agtcaaggtc gccaactgct tgccagtttg
     4981 tgtagtcgtt attgacagcc ttgtagagac ggacgaagcc ttttttctcc aagtcctgtc
     5041 caccgacgac agcatagtat tgacctttaa agttaaaaat ttgtggatcg cggaagtggt
     5101 cagtagagtc tgctggctgg tcaatcaaga tcttgtcaat ctttgtaatc ttaccctcct
     5161 tgtccatcaa agcaccgatc tggtatgggt gacggatcca gttttcatcg cgaacatttc
     5221 ctgtataaaa taggaataag ttatcgccaa attgcatggc agaaccagag taggcaccgt
     5281 ggctatctaa tggagtatct ggtaaaactt tgattccagt ttctttaaag tgaaccaaat
     5341 catcactttc tagctgtgcc caagatttca aaccgtgggc tgcaccaaaa ggaaaattct
     5401 ggtaaaagag gatccacttg ccatcaaagt aagaaaagcc atttgggtcg ttgagaagtc
     5461 ctgtttttgg ctcaacatgg taatgagtat gccatggaga ttgtgccata ttttccttta
     5521 tatgttgaat ttcttcttgc gtccaatctt gataaagtct gtaacgacgc tcagttgtcc
     5581 attccattca ttcctccaaa aatcttatca cttttaatag taactgtttt cgataaaaaa
     5641 tgcaagcctt ttatgttaaa aaagaggaaa aactgtcaaa cgattatcat aaaataaata
     5701 caggaaatca atcaaatttt tacgaaaatg tgaaagataa tgaaataaaa gactttttaa
     5761 ccaaggtttc aaacttattt ttcaaggaat tcctgatgaa acagtcaaaa acaatcaatc
     5821 taaaacttgc ccactaagtg gatagaatat tttttctgca aaacgcttga catattttta
     5881 aaacatgata aaataatagt cgtaagggcg aataaaatcg ctttcaaaca agaacaaaat
     5941 gttatataag gagatttttg caaatgaaca atcaggaaat tgcaaaaaaa gtcatcgatg
     6001 ccttgggcgg acgtgaaaat gtcaatagtg ttgcccactg tgcgactcgt ctacgtgtca
     6061 tggtcaaaga tgaagagaaa atcaataaag aagtgattga gaacttggaa aaagttcaag
     6121 gtgctttctt taactcaggg caataccaaa ttatctttgg tacaggtaca gttaacaaaa
     6181 tgtacgatga agttgttgta cttggattac caacatcatc taaggatgac atgaaagcag
     6241 aagttgctaa acaagggaac tggttccaac gtgctatccg tacttttggt gatgttttcg
     6301 ttccaatcat cccagttatc gtagcgacag gtctcttcat gggtgtgcgt ggtcttttca
     6361 acgctcttga aatgccactt ccaggtgact ttgcaactta cacacaaatc ttgacagata
     6421 cagccttcat catcttgcca ggtttggttg tgtggtcaac cttccgtgta tttggtggaa
     6481 atcctgccgt tggtatcgtt cttggtatga tgcttgtctc tggctcactt ccaaacgctt
     6541 gggcagttgc tcaaggtggt gaagtaacag cgatgaactt ctttggtttc atccctgttg
     6601 ttggtttgca aggttccgtt cttccagcct tcatcatcgg ggttgtcgga gctaaatttg
     6661 aaaaagctgt ccgcaaggtt gttccagatg tcattgacct cttggtaaca ccattcgtga
     6721 cacttttggt catgtctatc cttggactct ttgtcattgg accagttttc cacgttgttg
     6781 aaaattacat ccttattgct acaaaagcga ttcttagcat gccatttggt cttggtggtt
     6841 tcttgattgg tggggttcac caattgatcg tcgtgtcagg tgtgcaccac atcttcaact
     6901 tgcttgaagt gcaattactt gctgctgacc atgctaaccc attcaacgct atcatcacag
     6961 ctgctatgac agctcaaggt gctgctactg ttgcggttgg tgttaaaaca aaaaatccaa
     7021 aactgaaaac acttgctttc ccggctgctc tttctgcctt cctaggtatt acagagcctg
     7081 ctatcttcgg ggtgaacttg cgcttccgta aaccattctt cctttcattg attgctggtg
     7141 caatcggtgg tggattggct tctatccttg gacttgctgg tactggtaat ggtatcacca
     7201 tcatccctgg tacaatgctt tatgttggta acggacaact tccacaatac cttcttatgg
     7261 tagctgtatc atttgccctt ggttttgctc ttacttacat gtttggttac gaagatgaag
     7321 tagacgcaac tgcagctgca aaacaagctg aagtggctga agaaaaagaa gaagttgcgc
     7381 cagcagctct tcaaaatgaa acacttgtaa ctcctatcgt cggtgatgtt gtcgctcttg
     7441 ctgatgtcaa tgacccagtc ttctcaagtg gagctatggg acaaggtatc gctgtgaaac
     7501 caagccaagg cgtggtctat gcaccagctg atgctgaagt ttcaattgcc tttccaacag
     7561 ggcacgcttt tggtttgaaa acaagaaatg gtgctgaagt tttgattcat gttggtattg
     7621 atactgtatc tatgaacggt gacggttttg aaacaaaagt tgctcaaggt aataaggtga
     7681 aagctggcga tgttcttgga acatttgact caaacaaaat cgctgcagct ggacttgatg
     7741 atacaacaat ggttatcgtt acaaatacag gtgactacgc ttcagtagct ccagtcgcaa
     7801 caggttcagt tgctaagggg gatgctgtga tcgaagtgaa aatctaatca atcctctcta
     7861 atgtgaaaac gaacaaatga catgtttgtt cgtttttatt agatagtaag atttacagag
     7921 gaaaatctaa aaaatagaga catttagact ttcgaagtat gctataataa agaaaataaa
     7981 aacaagaggt ttatcatgac aaaattatat ggaagcttgg aagcgggcgg tacaaagttt
     8041 gtctgtgctg tcggtgatga aaactttaac gttgtagaaa aaacacaatt tccaacaaca
     8101 actccaatcg aaacaatcga taaaaccatt gagttcttct caaaattcga taaccttgct
     8161 ggtcttgcag ttggttcatt tgggccgatt gatattgaca aaaactcaaa aacttatggc
     8221 tttatcacga cgactccaaa accaaactgg gcaaatgtag acttgcttgg tgcccttcgt
     8281 cgcgccctaa acgtgccaat gtacttcaca acagacgtaa acagctctgc ttacggtgaa
     8341 atggttgccc gtaacaatgc tggtggtcgt atcgaaaact tggtttacta cacaatcggt
     8401 acaggtatcg gtgcaggcgt catccaacgt ggtgagttta tcggtggtgt gggtcaccct
     8461 gaaatgggtc attattatgt tgctagacac ccaatggata ttgaaaaaga gtttaagggt
     8521 gtttgtcctt tccataaggg atgtctagaa ggttatgcag ctggtccaag tttggaagct
     8581 cgtacaggtg tacgtgggga aactattgaa ctcaacaacc ctgtttggga tgttcaagcc
     8641 tactatatcg ctcaagctgc ggttaatgcg acagtgactt tccgcccaga cgtgattgtc
     8701 tttggtggag gggtcatggc tcaacaacat atgctggacc gtgtccgtga gaaatttaca
     8761 tctcttctta atggttacct accagtacca gatgtgcgtg actatatcgt gacgccagca
     8821 gtcgcaggaa atggttctgc cacacttggg aactttgttc ttgcaaaaga agtttcaaaa
     8881 taaagcacaa aatccgcttg ggaaaccaaa cggattttgt ggttgaaaac aatatttttg
     8941 agcctttcct taagtgatta cggacggtag cgactttctt cgaaattcca tacctaaact
     9001 ttgagacact aggctcaaag tttccgaata cctgaaacca ttagatttca ggtgtttcta
     9061 tcacggcgga aaggctaggt aagtcctcgc ctcactatcg aaaaatatgc atgatttcca
     9121 taccaaagta tatttagtat caagctatag ttaatctacg ctttaaaaat ccgcttggga
     9181 aaccaaacgg attttttacg tgtcaaagca tttgccagaa aaagtcaata atataggtca
     9241 gaccgtaggt ataaaccacg agggtaaagg gtttggtcag aatgatgatg gtcatgtagc
     9301 gcttgaaact catcttggtc agggcagcca gcatacagag aaagtcagct gggctaatgg
     9361 gccaaatcat cataaaaata aagaagcggt caaaacgatt gcccttatct agccagccga
     9421 tgtacttgtc gtaggtgcgc ttgctgacga cagactggac aaaggcagct ccgtataggc
     9481 gcactagata aaagataatg gcacagccaa tcacgatgcc gatatagttg tagatagtcc
     9541 cgatgatgtg cccgtagata aagaccccag ccaccgaggt caaggcccct ggaatgatag
     9601 ggacgacagt ctgtaaaatc tgtaaaaaga taaagagagg tggaccccag atgcctgcct
     9661 gctggataaa ggcagagagg gtttccttgg attgtaaaat cccagcctga taagcccaaa
     9721 tacagaaaat caaactccca accccaccga caatcgatga gatattgata actcgctgca
     9781 gaaggggaga aacagctttc atttgtttat cctgtgacat gtaaactcct catagatagt
     9841 atatttctac tataccatat tttggaggag aaagggggaa tgagtctttt ttgataagga
     9901 atagaaagta aatagccctt cgagacttag aataggtctg tcaactaaag gttatatgca
     9961 ttctaggttt cgaataatcg caattccata aatttaaaag cattctaagt ttcgaatagc
    10021 ttatctgaga taattttgag gcattcgcgc tttcgaatag tcattttccc taaagtttag
    10081 atgtattctg aagctagaaa gactaaaata taaaagtagt aagagtctct ctctgatgga
    10141 cgtaatttat ggctagtatg aatcctttga attgttagtt aattttaata ttaatcagtt
    10201 ctgaaataat tactaaatat agttagatgg tgaattaatt attgctaaat ttcaagttca
    10261 agttagtcat ccagaagtct tctctggggg acttgtagtt caagcatttt ttaggatagt
    10321 tgttaatcca cttttcgatg aatgcgactt cctttgtagt cattttctta gttccctgag
    10381 gtaaccatct atgaatgagt ctgttgtgat tttcattaga tcctatagtg atgtgcataa
    10441 tagatatagc agattgaaac tagaatagta tacatctact tctaaaacat tgttagaaat
    10501 caatttgact gtcctgatca atttgtcctg tttttatttc attttactat ataatcctta
    10561 gaaaacatat cggacaagcg gttgaattct gttccgtcca ttagtagata aaggattact
    10621 ccttcttgaa atgacagatg aacttgtttc ttataaaaat gttatctgaa actattcgct
    10681 tttttccaga agttttagag gaagaaaact ttatgaggaa aaaggagtta ctcaaataac
    10741 aattcaggat taaaaataga cagttgagga gcggaaggta taaattaagt ttgctactgt
    10801 ataatggatt tatcactaat actcttcgaa aatctcttca aaccacgtca gcttcgcctt
    10861 gccgtagata tagttactga cttcgtcagt tctatccaca acctcaaaac agtgttttga
    10921 gctgacttcg tcagttttat ctgcaacctc aaagctgtac tttgagcagc ctacggctag
    10981 ctttctagtt tgctctttgc ttttcattga gtataaaagt gctccaggcc atattttaca
    11041 cagcaatagt cttctaaaaa tggacaaaaa acattgtaaa ggctatcaaa aaggagtata
    11101 atgagtgcaa gaaatttcgg aggtgaaaga tgctagaagt aagaagtcta gagaaaagtt
    11161 ttggatccaa gcaagttttg tttggtattg actttcaagc gcgaccaggt cgtattttgg
    11221 gactagtcgg aaaaaatggt gctggaaaaa caacgatttt ccatagtatt ttgaaattcc
    11281 tagaatatca gggagaaatc ggtctggatg gtcaggatat tcgtcaggag acctatgctc
    11341 ggattggtta tctgcctgaa gaacgcagtc tcatgcctaa attgacagtt cttgaacaag
    11401 ttcgctactt ggcgactcta aaaggcatgg atgccaaaga agtcaaagaa aaactccctc
    11461 aatggatgaa gaggttggaa gtgaaaggaa agctgacaga taaaatcaag agtctgtcaa
    11521 aaggaaatca gcagaagatt cagctcatta ttactctgat tcatgaacca gacctgatta
    11581 tcttggatga gccttttagt ggattggacc cagttaatac agaattgctc aaacaagtca
    11641 tttttcagga aaaagagcgc ggagcaacca ttatcttttc tgaccatgtc atgaccaatg
    11701 ttgaggaact ttgtgacgat attctgatga ttcgagatgg ccgtgtggtc ttgcacggac
    11761 cagttcagga tgtccgcaat caatacggga aaacgcgtct ctttgtttca agtgaacgaa
    11821 gcaaggaaga attggaaaat cttcctcatg tcaaacaggt gagcttgacc aaacaaggca
    11881 gttggaaatt gattttggag gatgagagcg ctggaaggga actcttccca atcttgactc
    11941 aaggtcaata tatcgcaaca tttgaccaac aagcgccaac tatcgatgaa atctttaaac
    12001 tagaatcagg agtggaagta tgagaaatat gtgggttgta atcaaggaaa cctatcttcg
    12061 acatgtcgag tcatggagtt tcttctttat ggtgatttcg ccgttcctct ttttaggaat
    12121 ctctgtagga attgggcatc tccaaggttc ttctatggct aaaaataata aagtggcagt
    12181 agtgacaaca gtgccatctg tagcagaagg actgaagaat gtaaatggtg ttaacttcga
    12241 ctataaagac gaagcaagtg ccaaagaagc aattaaagaa gaaaaattaa aaggttattt
    12301 gaccattgat caagaagata gtgttctaaa ggcagtttat catggcgaaa catcgcttga
    12361 aaatggaatt aaatttgagg ttacaggtac actcaatgaa ctgcaaaatc agcttaatcg
    12421 ttcaactgct tccttgtctc aagagcagga aaaacgctta gcgcagacaa ttcaattcac
    12481 agaaaagatt gatgaagcca aggaaaataa aaagtttatt caaacaattg cagcaggtgc
    12541 cttaggattc tttctttata tgattctgat tacctatgcg ggtgtaacag ctcaggaagt
    12601 tgccagtgaa aaaggcacca aaattatgga agtcgtcttt tctagcataa gggcaagtca
    12661 ctatttctat gcgcggatga tggctctgtt tctagtgatt ttaacgcata ttgggatcta
    12721 tgttgtaggt ggtctggctg ccgttttgct ctttaaagat ttgccattct tggctcagtc
    12781 tggtattttg gatcacttgg gagatgctat ctcactgaat accttgctct ttattttgat
    12841 cagtcttttc atgtacgtag tcttggcagc cttcctagga tctatggttt ctcgtcctga
    12901 agactcaggg aaagccttgt cgcctttgat gattttgatt atgggtagtt tttttggagt
    12961 gacagctcta ggtgcagctg gtgacaatct cctcttgaag attggttctt atattccctt
    13021 tatttcgacc ttctttatgc cgtttcgaac gattaatggc tatgcggagg gagcggaagc
    13081 atggatttca cttgctatta cagtgatttt tgcggtggta gcaacaggat ttatcggacg
    13141 catgtatgct agtctcgttc ttcaaacgga tgatttaggg atttggaaaa cctttaaacg
    13201 tgccttatct tataaataga agagccttgc gaaagcgagg tttttaaagg tgaaaagggt
    13261 ggaatcacga acctaattat gtacacatta tgtaaacagg ttgcttgaaa actcaattgt
    13321 atagtgaact gaatctggaa taggataata ttacttctaa aacattctta taaattgatt
    13381 tgaattccaa aatcccatcg ttccgttctt atttcatttt gcgatatagt gaaaggaaat
    13441 aagtcagctc acaaaaaacg cataatatca aggattttta acacttgata ctatgcgttt
    13501 tctaattgta aagacttttt gcctggtctc ttttgttcta tgagtatgtt acatatctag
    13561 gtaaaaatta tttaaagcaa attaacctta tttctcaaga tgtagtaggt tccgagataa
    13621 aagatagcta tgaatatgag ttctttaaca atggctatac ctgctcccat atagaaatgg
    13681 tcattgagtc ctaccagtga attgacatag aaattagaac taagattgaa gaaaagttca
    13741 ataaatccaa tgacgatttg gataccaatg taggctgcaa cagcgagtgc tgtacggtat
    13801 tcattgaaaa gctgtccaat ggaaatagcc aggtagatgc agaggattcc tgaaatggta
    13861 tttagtagga aggatatacc tgtaagaaag atctgaggga gatgtgtttc tacaaatgta
    13921 atcacataag aaagaggaat ccattctgga gctgttaaag ccagaataat aacagcactt
    13981 agagccaata cagcggtgct aatcaatgac cagataaagg caccgattag tttggctgtg
    14041 atgatatggt gttcagaaac tggcaaggtc aaagtcagat agccttgtcg gtcgtagaca
    14101 ctacctttga agcgtttaat aatcaagaaa atggttgaaa tcccaagtgt aagcatcaag
    14161 ccaccaaaga ctgtagctag aaaaagtagc atagtagcct gactttcttg gtaaggtaga
    14221 tttttaaagc cttgtgtctg tattccgatg agggcagaaa ggactagcac ggctgcgtag
    14281 agggctaaat accacttgtt aacattttta aattcgtagc gaactaaatt ccaaaacata
    14341 aataatctcc tttgcttagg ccttaaattc ctgacggaag agttggtcaa tggattcacc
    14401 tgactcgtag cgaatatcat ctacatttcc ttgacggacg acttttccgt cttttaggaa
    14461 gacaatttca tccaagattg gctcgatatc agaaatcaag tgggtagaaa tcaaaacggt
    14521 agaagttggt gagtagttgt tgataatggt attgaggata taagcacggg ctgctggatc
    14581 caccccacca atgggttcgt ccaaaacata gagacgagca tcacggctca taaccaaaat
    14641 cagttgaacc ttttctttgt ttccttttga tagtttcttg agacgactat tttcatcaat
    14701 gcccaggtct gcaagtagat gatgggcgcg ttcaagattg aaatctttat agaaggtctt
    14761 gaagtaggtt agggcttctt tgaccttcat ttgctcattg agataggtcg tatcaggcaa
    14821 ataagctaca acggccttgg ttgctgggct tgggtccatg tcgttgatga ggacacgtcc
    14881 ttgatctggt tgtaagaggc cattaattag tttaatcagg gttgtttttc ctgagccgtt
    14941 tggcccaaga aggccgacaa tttttccagc tggaatgtca agagaaacat tttcaagggc
    15001 tggtgttgct ccatatgatt tggatacatt ttcaaatact agtaatgaca taggcttaaa
    15061 ctcctttaat ataatcactg actacgcctg gtagttcttc tttttcatag ccaaaatggg
    15121 tcatggagga aacgaagtgt tccaattctt cttctgataa ttgtttgcgt gactgggcga
    15181 ttagctcctt atccttagtc acaaatcgtc cagttgttcg cttgctgtag acaaatcctt
    15241 ctcgttcaag gtctgataag gctctttgga tggtattggg attgacacca gcctcgctag
    15301 ctagctccct cacggttgga agttgttgat tgggttccag tgtatgggaa acaatctgaa
    15361 gcttgatttt ctccataatc tgtaaataga tgggtttttt gttgtcaaat gtccaggaca
    15421 tcttagtctc ctttctctta tccttttgtc ttaattaaat aatacaacaa aacaaaaaac
    15481 ttgtcaagca aaaagaagaa ttgttttggg aatcgcttaa aaaatggtat aatgaaaaga
    15541 aaacgataag gagggaaagg atgcgttgtc caaaatgtgg ggctaccaag tcaagtgtta
    15601 tcgatagtcg ccaagcagaa gaagggaaca ccattcgtag aagacgtgag tgcgacgaat
    15661 gccaacaccg ttttacaacc tacgaacgag tagaagaaag aaccttagtg gttgttaaaa
    15721 aagatggtac acgggaacaa ttctccagag ataaaatctt taatgggatt atccgctcag
    15781 cccagaaacg tcctgtgtca agtgatgaaa tcaacatggt agtcaatcgt atcgaacaga
    15841 aactccgtgg tcgaaatgaa aatgaaattc aaagtgagga cattggttca ctcgtcatgg
    15901 aggagttggc tgaattggac gagattacct atgtacgttt tgctagtgtc tatcgtagtt
    15961 ttaaggatgt cagtgagtta gagagcttgc tccaacaaat cacccagtcc tctaaaaaga
    16021 aaaaggaaag ataaatgaag ccaattgacc gtttttctta tctaaagaat aatcgggtgt
    16081 cgcaagatac ctcatctctg gtacagtgct acctcccgat tatcggtcag gaggcactga
    16141 gcctttatct ttatacaatc agtttttggg ataatggtag aaaggaatat cttttttcaa
    16201 gtatcctcaa tcatctcaac tttgggatgg atagactgat aaaatcattg aaaatcttat
    16261 ctgcttttaa tctcttgacc ctctatcaaa agggggatgt ttatcagcta gccctccatg
    16321 ctcctctatc tagtcaagac ttcttggagc atcctgttta tcgcagactc ttagagaaaa
    16381 agattggcga ctctgctgtg gaggatttga aagttgaaag tgctgatggt gaagaaatac
    16441 ctgtctcact caatcaagtc tttccagaat tggcagaact aggcagtcaa gaagaccttg
    16501 gtctcaagaa gaaagtggcc aatgattttg acttggaaca ttttcgccag ctgatggctc
    16561 gagatggact tcgttttgcg gatgagcagt ccgatgtctt aaacctcttt gctattgccg
    16621 aggagaagaa atggacttgg tttgaaacct atcaattggc caagtcaaca gctgtttctc
    16681 aggttatttc aaccaaacgc atgcgtgaaa aaattgctca aaaaccagtt tcctctgact
    16741 ttagtcttaa ggaaacaacc attatcaaag aagccaaaag taaaactgcc ctgcagttct
    16801 tggcagaaat caagcaaaca cgcaagggaa ccattaccca aacagaaaga gaactcttgc
    16861 aacagatggc tggcttgggc ttgctggacg aagtcatcaa tatcattctt ttattgacct
    16921 ttaataaggt cgattcggca aatatcaatg agaaatatgc catgaaggta gccaatgact
    16981 atgcctatca aaagattcat tcggcagaaa aggcagtctt gcgcatccgt gagcgaggac
    17041 agaaagcaaa aacacaaaaa cagaatcaga ctgccccagt aaaaaccaat gttcctaaat
    17101 ggagtaatcc tgaatataag aatgaaacca gcgaggaaac tcgtctggaa ctagaacgta
    17161 agaagcaaga actattagct cgattagaaa aaggaggaga ttagatggaa agtgtcggag
    17221 acgtactcaa acgtcaaccc agccgttttt attatcaaga tttggtccag aaaatcatga
    17281 aggaccctga tgttgcggct tttatccagc aagaatcctt gactccagag gaattaaatc
    17341 gcagtatctc caagtttaat cagtacatca ccgagcgtga caagtttctc cgtggggata
    17401 cggattatat tgccaaaggc tacaagccga ttttggttaa gaatcatggc tatgcagatg
    17461 tttcatatga agaaactcct gagctaatcg cggctgaaaa agaagcggct attaagaacc
    17521 gtctcaagtt aatcaatcta ccagccagtc tcaagaaagc tagtttggct caagttgact
    17581 tggatgattt ggggcgctta ccagtttttg aaaagctact agccttcgtg gagcaatatc
    17641 cagctattcg aaaaggtctt tacttatatg gagactttgg tgtgggtaaa agtttcatgg
    17701 tggcggcctt agctcatgat ttatcagaaa aacgtggtgt ttcatcaact ctcctccact
    17761 atcctagctt tgtcattgat gtcaaaaatg ctatcagtga tggcaatgtt aagaccttgg
    17821 tggatgagat taagctgtct gaggtcctga ttttagatga tattggcgcc gagcaatcaa
    17881 ccgtttgggt gcgtgacgaa atcctgcagg tcattctcca atatcggatg caggaaaatt
    17941 taccgacctt tttcacatcc aacttcaact ttgaagattt ggagaagcat tttgcgaaag
    18001 tgaaacatgg aaatgacgaa acctgggaag ccagacgggt catggaacgc atccgttatt
    18061 tggctgagga gactcgttta gaaggagtaa accgtcgatg acagaaacca ttaaattgat
    18121 gaaggctcat acttcagtgc gcaggtttaa agagcaagaa attccccaag tagacttaaa
    18181 tgagattttg acagcagccc agatggcatc atcttggaag aatttccaat cctactctgt
    18241 gattgtggta cgaagtcaag agaagaaaga tgccttgtat gaattggtac ctcaagaagc
    18301 cattcgccag tctgctgttt tccttctctt tgtcggagat ttgaaccgag cagaaaaggg
    18361 agcccgactt cataccgaca ccttccaacc ccaaggtgtg gaaggtctct tgattagttc
    18421 ggtcgatgca gctcttgctg gacaaaacgc cttgttggca gctgaaagct tgggctatgg
    18481 tggtgtgatt atcggtttgg ttcgatacaa gtctgaagaa gtggcagagc tctttaacct
    18541 acctgactac acctattctg tctttgggat ggcactgggt gtgccaaatc aacatcatga
    18601 tgtgaaaccg agactgccac tagagaatgt tgtctttgag gaagaatacc aagaacagtc
    18661 aactgagaca atccaagctt atgaccgtgt gcaggctgac tatgctgggg ggcgtgcgac
    18721 cacaagctgg agtcagcgcc tagcagaaca gtttggtcaa gctgaaccaa gctcaactag
    18781 aaaaaatctt gaacagaaga aattattgta gaaagtgaga aattatggcc ctaccaacta
    18841 ttgccattgt aggacgtccc aatgttggga aatcaaccct atttaatcgg atcgctggtg
    18901 agcgaatctc cattgtagaa gatgtcgaag gagtgacacg tgaccgtatt tatgcaacgg
    18961 gtgagtggct caatcgttct tttagcatga ttgatacagg aggaattgat gatgtcgatg
    19021 ctcctttcat ggaacaaatc aagcaccagg cagaaattgc catggaagaa gcagatgtta
    19081 tcgtctttgt cgtgtccggt aaggaaggaa ttaccgatgc agacgaatac gtagcccgca
    19141 agctttataa gacccacaaa ccagttatcc tcgcagtcaa caaggtggat aaccctgaga
    19201 tgagaaatga tatctatgat ttctatgctc tcggtttggg tgaaccactg cctatctcat
    19261 ctgtccatgg tatcggtaca ggggatgtac tagatgcgat tgtggaaaac cttccaaatg
    19321 aatatgaaga agaaaatcca gatgtcatta agtttagctt gattggtcgt cctaacgttg
    19381 gaaaatcaag cttgattaat gctatcttgg gagaagaccg tgtcattgcc agtcctgttg
    19441 ctggaacaac tcgtgacgct attgataccc actttacaga tacagatggt caagagttta
    19501 ccatgattga tacggctggt atgcgtaagt ctggtaaggt ttatgaaaat actgagaaat
    19561 actctgttat gcgtgccatg cgtgctattg accgttcaga tgtggtcttg atggtcatca
    19621 atgcggaaga aggcattcgt gagtacgaca agcgtatcgc aggatttgcc catgaagctg
    19681 gtaaagggat gattatcgtg gtcaacaagt gggatacgct tgaaaaagat aaccacacta
    19741 tgaaaaactg ggaagaagat atccgtgagc agttccaata cctgccttac gcaccgatta
    19801 tctttgtatc agctttaacc aagcaacgtc tccacaaact tcctgagatg attaagcaaa
    19861 tcagcgaaag tcaaaataca cgtattccat cagctgtctt gaacgatgtc atcatggatg
    19921 ccattgccat caacccaaca ccgacagaca aaggaaaacg tctcaagatt ttctatgcga
    19981 cccaagtggc aaccaaacca ccaacctttg tcatctttgt caatgaagaa gaactcatgc
    20041 acttttctta cctgcgtttc ttggaaaatc aaatccgcaa ggcctttgtt tttgagggaa
    20101 caccgattca tctcatcgca agaaaacgca aataaaaaat tagaatctgg aatgacagtt
    20161 ccggattttt ttgatataat aaaatgatag aaaacgctat caaaagaagg gggatgtcgg
    20221 tgatggaaca tttgtttaaa ttcttacttt tagcaccgta cttttatttt gataactgga
    20281 ttgagaaggc caacagaaat agtaagtttt ttccaatttt ttattatttt tactggtttt
    20341 acatcccctt ctattctctt tttagccttg cttggacagt tgtttcagtt ctgtttttca
    20401 ataccgtctt gagaaatgtg acagatatca agttatgggg catttggttt ctttttattc
    20461 tgctagctat tggtatgaat tggttaactt attcctgttt caaagaaatg tttcgcttga
    20521 gacaggaact agggaagtct aagggtggaa ggcattgatt tatatcggtt tctatttgta
    20581 ggaggtggct tatggtacct ctaaaatcat ttattacacg ctattccaag gtttatattg
    20641 gtaataacat ttaatagaac gaaactaaag aaaacaattt aaaaaaggag gcttgtgatg
    20701 gaacacttgt ttaaaatggt aatcttatta ccctgttttt actttttcag ctggattgac
    20761 aaggataata gagaaagtaa atttttccca attttttact atttttactg gatttacatc
    20821 accctctatg ctctttttag ccttgcttgg acagtttttt cagttctgtt tttcaatatc
    20881 gtcttgagaa atttgacaga tatcaagtta tggggtattt ggctattatt actacttatc
    20941 gcttttgcta gtgattggtt agcctatgtc tttttcaaaa aaatgattcg cttgaggcgg
    21001 gaactaggga aatctaaagg cggaaggcat tgatttatac tcttcgaaaa tctcttcaaa
    21061 ccacgtcaac gtcgccttgg attatatatg taactgactt cgtcagtctt atctacaacc
    21121 tcaaagcagt gctttgagca acttgcggct agtttcctag tttgctcttt gattttcatt
    21181 gagtattata ttactttcta tttgtaggag gtggcttatg aagattcctc tcttaacttt
    21241 ggcaaggcat aaatttgttt atgtcttgct tactttgctt tttcttgctt tggtttatcg
    21301 tgacgttttg atgacttatt tcttttttga tattcatgcg cccgatctag ctaaattcga
    21361 tggacaagca attaaaaatg acttattaaa atcagcatta gattttcgta ttctccagtt
    21421 caatctaggt ttttatcaat catttattat tccaatcatc attgttttgc taggttttca
    21481 atatattgag ctgaaaaata aagttttacg attgagtatt ggaagagaag tgagctatca
    21541 agggttaaaa agaaagttga ctttgcaagt tgcaagtatc ccttgtttga tatatttagt
    21601 gactgtgctg ataattgcaa ttataaccta tttctttggg actttttctc ctcttggatg
    21661 gaattctcta ttttctgatg ggagtagttt acaaaggctc ctagatggag agataacaag
    21721 ctatttgttc tttacttgtg tcctactaat cggtattttc atcaatgcaa tctatttttt
    21781 acaaatagtt gattatgtgg ggaatgtgac tcgttcggca atcacctatt tgatgtttct
    21841 ttggcttgga tctatgctgc tctatagtgc cttgccttac tatatggttc ctatgacgag
    21901 tttgatgcaa gctagctatg gggatgtaag tttgatgaaa ctctttactc cttatatcct
    21961 ttatgttgtc ccttatatgg tacttaaaaa atatgaagat aatgtttaag aattttaaca
    22021 atatttggct aaagagaaag atcgttttac tacttcgtat agttctgatg atgattttga
    22081 taaactatct attgtcaaca gcggttcaaa agcaggatgc tgttatcttt ttcaagagag
    22141 aattgatttc aattttttcc tataatgact attctgaagc gaatttagaa atccccaaac
    22201 tcttgttaaa cctttcactt ttcatggtag gatggctctc tgtcatttta cttgaaagtg
    22261 atttggcaga ccattaccat cacttgattc gctatcaatc aagctccttt ttcgattata
    22321 caaggaaacg attggttgtc atttctaaat tttttactca agatttgttt gtctggtttc
    22381 ttggtttact tccgctagga attcatttca aaacagtcgc acttttcttt ttacttgctc
    22441 agttaatgat gttgtactta ctactgtctt atctgatagc actgattagt gcgggcgctg
    22501 gtttttcttt ttttctctat tttttggcat ttgtgggaca agaatggatg atggatcata
    22561 ttgtaacagt gtatttagta ctcttaagtt tattagttat gttgattgtt agtcgcttgg
    22621 aagagaaatt taagaaagga taaacgatga gacttgaaat tataaatgga cagaaaattt
    22681 atgggaaaag acctatttta aatcagttga atttggtgtt tcaatcagga aaaatttatg
    22741 gacttaaagg tgataatgga tctggcaaga cggttctttt aaagatactt gctggttata
    22801 ttaagcttga caaaggaaaa gttcttcaag atggtaaagt ttacggggta aaaaatcatt
    22861 atattcagga tgcaggaatt ttaattgaaa aagtcgagtt tttatctcat ttatccctga
    22921 gagaaaattt ggaactgtta aggtattttt catctaaagt tacggaaaaa agaattgcct
    22981 attggattca atactatgat ttacaggaat ttgaagacat tgaataccgt catttatcct
    23041 taggaacaaa gcaaaaaatg gccttgattc aagcctttat ttcctctcct tctatactct
    23101 ttctcgatga acctatgaat gctttggatg agaaaagtgt gaggttaacc aaacaggtca
    23161 ttttatctta cctgaaaaaa gaaaatggtc tggttatcct gacatcgcac atatcggaag
    23221 atatttcaga cctttgtaca gatgtattag ttgtcgaaaa tggacatata caaatgtaaa
    23281 ggatatacaa tcctaggaga tggcttatgg cacatctaaa atcatttatt acacgctatt
    23341 ccaaggttta tattggttta gttctgctga tctggctgtc tttcttcttt atcccttggg
    23401 ataaaccact tctggggata aggattgaca tcttcatcat acagaaaatc ttgctagctt
    23461 ttggaattct gtccattctc atggccttgc tgtccaagaa agtcagtctc tttgtttttg
    23521 gactgatttg ctgtctttct ctttggatta acttatttat cacatttgcc attttgccga
    23581 tttttggcaa ttaaacagtc ataaaagttg gagaggttag cttgaaaact aacctctttt
    23641 tccttttcaa aatggggatt cttccttgaa aataatcagt aattgtgcta aaattaaagg
    23701 aacattctaa aatattcgga atttaaagta aggaaaaaca tggctaatat tttaaaaaca
    23761 attatcgaaa atgataaagg agaaatccgt cgtctggaaa agatggctga caaggttttc
    23821 aaatacgaag accaaatggc tgctttgact gacgaccaac taaaagcaaa aacagttgaa
    23881 tttaaggaac gttatcaaaa tggagaatca ctggattcat tgctttacga agcatttgcg
    23941 gttgtccgtg aaggtgccaa acgtgtccta ggtctcttcc cttataaggt tcaggtcatg
    24001 ggggggattg ttcttcacca tggtgacgtg ccagagatgc gtacagggga agggaaaacc
    24061 ttgactgcga ccatgccggt atacctcaat gccctttcag gtaaaggggt tcacgtagtt
    24121 acggttaatg aatacctgtc agaacgtgac gcgactgaga tgggtgaatt gtactcttgg
    24181 cttggtttgt cagtagggat taacttggct accaaatctc caatggagaa aaaagaagcc
    24241 tatgagtgtg atattactta ctcaactaac tcagaaatcg gatttgacta ccttcgtgac
    24301 aacatggtcg ttcgcgccga aaacatggta caacgtccgc ttaactatgc cttggtcgat
    24361 gaggttgact ctatcttgat tgacgaggct cgtacacctt tgattgtatc aggtgccaat
    24421 gcggttgaaa ccagtcagtt gtatcacatg gcagaccact atgtaaaatc tttgaacaaa
    24481 gatgactaca tcatcgatgt gcagtctaag actattggtt tgtctgattc agggattgac
    24541 agggctgaaa gctacttcaa acttgaaaac ctctatgaca tcgaaaacgt ggctttgact
    24601 cactttatcg ataacgccct tcgtgccaac tacatcatgc ttctcgatat tgactatgtg
    24661 gtgagcgaag agcaagaaat cttgattgtc gaccaattta caggtcgtac catggaaggt
    24721 cgtcgttatt ctgatggatt gcaccaagct attgaagcca aagaaggtgt gccaatccag
    24781 gatgaaacca agacatctgc ctcaatcacg taccaaaacc tcttccgtat gtacaagaaa
    24841 ttgtctggta tgacgggtac aggtaagact gaggaagaag aattccgtga aatctacaac
    24901 attcgtgtta ttccaatccc aacaaaccgt cctgttcaac gtattgacca ctcagacctt
    24961 ctttatgcaa gtatcgaatc taagtttaaa gcggttgtcg aagacgttaa ggctcgttac
    25021 caaaagggtc aacctgtctt ggttggtaca gtagcggttg aaactagtga ctacatttct
    25081 aagaaattgg ttgcagctgg tgttcctcac gaagtcttga atgccaaaaa ccactataga
    25141 gaagcccaaa tcatcatgaa tgctggtcaa cgtggtgccg ttaccatcgc aaccaacatg
    25201 gcgggtcgtg gtaccgacat caagcttggt gaaggtgttc gtgaacttgg aggactttgt
    25261 gttattggta cagaacgtca tgaaagtcgt cgtatcgata accagcttcg tggacgttca
    25321 ggtcgtcaag gagatccagg tgagtcacaa ttctacctat ctcttgaaga tgatttgatg
    25381 aaacgttttg gttctgaacg cttgaaggga atctttgaac gtctcaacat gtctgaagag
    25441 gcgattgagt ctcgcatgtt gacgcgtcag gttgaagcag cgcaaaaacg tgtcgaagga
    25501 aataactacg atacccgtaa acaagtcctt caatacgacg atgtcatgcg tgaacaacgt
    25561 gagattatct atactcaacg ttatgatgtc attactgcag accgtgactt ggcacctgaa
    25621 attcaggcaa tgatcaaacg cacgattggt cgtgtcgttg acggtcatgc gcgtgctaaa
    25681 caagatgaga aactagaggc aattttgaac ttcgctaagt acaacttgct tcctgaagat
    25741 tctattacga tggaagactt gtcaggcttg tctgataagg ccatcaagga agagcttttc
    25801 caacgtgcct tgaaggttta cgatagtcag gtttcaaaac tacgcgatga agaagcagtt
    25861 aaagaattcc aaaaagtttt gattctacga gtggtggata acaagtggac agatcatatc
    25921 gatgcccttg atcaattgcg taacgcggtt ggacttcgtg gctatgctca gaacaaccct
    25981 gttgttgagt atcaggcaga aggtttccgt atgtttaatg atatgattgg ttcgattgag
    26041 tttgatgtga cacgcttgat gatgaaagca caaattcatg aacaagaaag accacaggca
    26101 gaacgtcata tcagtacaac agcgactcgc aatatcgctg ctcaccaagc aagtatgcca
    26161 gaagatttgg atttgagcca gattggacgc aatgaacttt gcccatgtgg ttctggtaag
    26221 aaatttaaaa actgtcacgg taaaagacaa taaaatgaga tagtttagag gcggatatct
    26281 tgtgaaaagt aaatttttac tgggtatccg tttgctttat aaggagatga gttatggtat
    26341 ttacagcaaa aagctctaaa ataaatatag aagaagttcg tgccttgtca aaattagaag
    26401 gtcaggcttt ggagaggaaa tcacagcgag atcaagagct agaagccatt atacgtggag
    26461 aagaccagcg aattctcttg gtaatcgggc catgctcatc tgacaacgaa gaagctgtcc
    26521 ttgaatacgc taagcgtttg gcagtcctac aagaagaagt ggcagatcgt atctttatgg
    26581 ttatgcgtgt ttatactgcc aaaccccgta ccaacggaga tggctataag ggcttgattc
    26641 accagcctaa cgcgacagaa gcgcctagtc ttatcaatgg aatcaaagcc gttcgccatc
    26701 ttcactatcg tgtcatcaca gaaacaggga tgacaactgc tgatgaaatg ctttatcctg
    26761 aaaaccttcc gcttgtagat gatttgattt cttacatggc agttggtgcc cgttcagttg
    26821 aagaccagca acaccgcttt gtggcaagtg gggcaggatt ttctactggt tttaaaaatc
    26881 caacctctgg aaatctcaat gtcatgttta atgggattta tgctgctcaa aacaaacaaa
    26941 gtttcctttt cttaggaaaa gaagtagaaa caactgggaa cccgctttca cacgctattc
    27001 ttcgtggtgc tcttaatgag tatggaaaaa atattcccaa ctactattat gacaatttaa
    27061 ttgataccat tgcccagtat gagaaaatgg gcttggaaaa tccttttatc atcattgata
    27121 ccaatcatga caattctggt aagcagtata ttgaacagat ccgaattgtc cgccagacct
    27181 tgattaaccg tgcttggaat gaaaaaatta agcagttcgt tcgtggtttt atgattgagt
    27241 cttatctgga agatggtcga caaaatgagc cagaagtatt tggtaagtct atcacagacc
    27301 cttgcctggg ttgggataac acagaagctc ttgtcagaga aatttacaaa acgttaggag
    27361 aataagatgg catttattga aaaaggtcaa gaaatcgata tggaagtcat caaggctgaa
    27421 acccaattgt ctgcggaagc cttgagactc aaggaaagcc gtgacaggga attggcagat
    27481 attatttcag gggaagatga ccgtattctc ttggtgattg gtccttgctc ttctgataat
    27541 gaagaggcgg tcttggaata tgctcgccgt ttatccgcct tgcaaaagaa ggtagcggac
    27601 aagattttca tggtcatgcg cgtgtatact gctaagcctc gtaccaatgg agacggctat
    27661 aaaggattgg ttcaccagcc agatacttcc aaggctccaa gcttgattaa cggcttgcag
    27721 gctgtgcgcc agttgcacta ccgcgtgatt acagagactg gtttgacaac ggcagatgag
    27781 atgctttatc cgtcaaatct gatcttggtg gatgacttgg tcagctacca tgccgttgga
    27841 gctcgttctg tggaagacca agagcaccgc tttgtggctt ctgggattga tgcaccagta
    27901 gggatgaaaa atccaacctc aggaaatttg ggtgttatgt ttaacgccat ctatgctgct
    27961 caaaacaagc aaaccttcct ttatcatggg caggaagttg agacatcagg taatcctttg
    28021 gcccatgtta tcctccgtgg agcagtcaac gagtatggca attatatgcc gaattactac
    28081 tatgaaaacc tactccaagc cattgaacgc tatgaaacca tgggacttga aaatcctttt
    28141 atcctcattg acaccaacca tgataactca ggcaagcaat atatggagca gattcgaatt
    28201 gttcgccaga ccttgcagaa tcgtgattgg aatgagaaaa ttaaaaagac ggttcgagga
    28261 tttatgattg aatcttacct agcagatggt cgtcaaaacc aaccagagat ctttggttgc
    28321 tctattactg acccttgcct aggttgggaa aatacagagg ccttggtaga agagatttat
    28381 gttaccttga caaaataagt gaaaaggatg gagttgggga atctcaactc cttttgatga
    28441 gaatgatagt tggacacgga attgacatcg aagaattggc ttcgatagaa agcgcagtta
    28501 cacgacatga aggatttgct aagcgtgtac tgaccgctca ggaaatggag cgcttcacca
    28561 gtctcaaagg acgcaggcaa atagaatatt tagctggtcg ctggtcggct aaggaggcct
    28621 tttccaaggc tatgggaacg ggtattagca agctcggttt tcaggatttg gaagtcttga
    28681 acaacgaacg tggggcgcct tattttagtc aggcaccatt ttcaggaaag atttggctgt
    28741 ctatcagcca caccgatcag tttgtgacag ccagtgtcat tttggaggaa aatcatgaaa
    28801 gctagtccac atagaccaac caaggctctg attcatctgg gagctattcg acaaaatatt
    28861 cagcaaatgg gggctcatat ccctcaagga acgctcaagt tggctgtggt taaggccaat
    28921 gcttatggtc atggagctgt tgccgttgcc aaggcaattc aagatgatgt tgatggcttt
    28981 tgcgtttcca atatcgatga agccattgaa ctcagacaag ctggactcag caagccaatc
    29041 ctcattttag gagtttctga aatcgaagct gttgctctag ctaaagaata tgacttcacc
    29101 ttgacagtgg ctggactgga gtggattcaa gcactcttag ataaggaagt ggacctaact
    29161 ggattgacag tccacctcaa gattgattca gggatgggac ggattggttt tagagaggcc
    29221 agtgaggttg agcaggctca agatttgctc caacaacacg gtgttcgtgt tgaaggaatc
    29281 tttacccact ttgctactgc tgatgaggaa tcagatgact attttaatgc ccagttagaa
    29341 cggtttaaaa ctattttagc tagtatgaag gaagttccag agctggttca tgctagcaat
    29401 tctgcaacga ctctttggca tgtagagact attttcaatg cggttcgtat gggagatgcc
    29461 atgtatggcc tcaatccaag tggagcggtc ttggatttgc cttatgattt gataccggcc
    29521 ttgaccttgg agtctgctct ggttcatgtc aagacagttc cagctggagc ttgcatgggc
    29581 tatggagcaa cttatcaagc ggatagcgag caagtcatcg cgaccgtgcc aatcgggtat
    29641 gcagatggat ggacaagaga catgcaaaat ttctctgtct tggtagatgg ccaagcttgc
    29701 ccaattgtcg gcagggtttc gatggaccaa atcactattc gattgcctaa gccttaccca
    29761 ctcggaacca aggtaacctt gattggctcc aatggggata aggaaatcac tgcaactcag
    29821 gtagcgacct accgcgtaac cattaactat gaggtggttt gcctcctcag cgaccgtatt
    29881 ccgagagaat attattagaa aagaaaggag tggagcatga atctacatca acccttgcat
    29941 gtcttgcctg gtgtgggacc aaagtcagca gaaaaatacg ccaaactagg aattgaaaac
    30001 ttgcaagatc tcttgctcta ctttcctttc cgttatgaag acttcaaaac caagcaggtg
    30061 ctggagctgg aagacggtga gaaggcagtt ctttctggtc aggtagtgac tcctgctagt
    30121 gtccagtatt atggtttcaa gcgcaatcgc ctgcgtttta gtctcaagca gggagaggtc
    30181 gtttttgcgg tgaatttctt taaccagccc tatctggctg ataaaataga gttgggagca
    30241 acccttgctg tctttggaaa atgggaccgc gctaaggcta gtctgactgg gatgaaggtt
    30301 ctggctcagg tagaagatga cctccagcct gtttatcgtc tggctcaggg aatcagtcag
    30361 gccagtctgg ttaaggtcgt caagacggct tttgatcagg gactggacct cttgatagaa
    30421 gaaaatctgc cccagtcttt actagacaaa tacaaactca tgtcccgttg tcaggcagtc
    30481 cgagctatgc attttccaaa ggatttggca gaatacaagc aggctcttcg ccgtatcaag
    30541 tttgaggaac tcttttattt ccaaatgcag ttgcagacgc tcaagtctga aaatagagtt
    30601 cagggaagtg gtctggttct gaattggtct caggaaaaag tgacagcagt taaagtaagt
    30661 cttccttttg ccctgaccca agctcaggaa aagagtttgc aggaaatttt aactgatatg
    30721 aagtccgacc accacatgaa tcgtctccta caaggagatg tggggagcgg aaaaacggta
    30781 gtcgctggct tggccatgtt tgcggcagtg acagcaggtt atcaggctgc cctaatggta
    30841 ccaacagaaa tcctcgcaga gcaacacttt gagagtttac agaacctttt tcccaatttg
    30901 aaactggctc tcttgacagg ttccttgaaa gctgcagaaa agagagaggt cttggagacc
    30961 attgccaagg gtgaggctga tttgattata ggaactcacg ctctgataca agatggggtg
    31021 gagtatgctc gtcttggttt gattattatc gatgagcagc accgttttgg tgtggggcaa
    31081 aggcgtattt tacgggaaaa aggcgacaat ccagatgtcc tcatgatgac ggcgactccc
    31141 attccacgga cgcttgccat cacagccttt ggagatatgg atgtttccat tatcgaccag
    31201 atgccagcag gtcggaagcc tattgtgacg cgctggatca aacatgagca actacctcag
    31261 gtcttgactt ggttagaggg ggaaattcaa aaaggttccc aagcctatgt catctctcct
    31321 ttgattgaag aatcagaagc tctagatttg aaaaatgcca ttgccttatc agaggagttg
    31381 acgactcatt ttgcaggcaa ggcagaggtg gctcttctac atggtaggat gaagagtgac
    31441 gaaaaagacc agatcatgca ggatttcaag gagagaaaga cggatattct ggtttcgacg
    31501 acggttattg aggttggggt caacgttccc aatgcgactg tcatgattat catggatgcc
    31561 gatcgcttcg gtctcagtca acttcaccag cttagaggtc gtgtcggtcg gggggacaag
    31621 cagtcctacg ctgttctcgt tgccaatccc aagacggatt ctgggaaaga ccgcatgcgc
    31681 atcatgacag aaacgaccaa tggatttgtc cttgcggagg aagatttgaa aatgcgtggt
    31741 tctggtgaga tttttggaac cagacagtca ggacttccag agttccaagt ggctgatatt
    31801 atcgaagatt ttccgatttt agaagaagca agaaaggttg ctagctacat tagttctata
    31861 gaaacttggc aagaagatcc agagtggcgc atgattgccc ttcatctgga aaagaaagaa
    31921 catctggatt aagctttctc taaggaaaac ttaagctagt ttttagattt ggctcttata
    31981 ctaaagtcat caaaaagaaa cgaggactct catatgacag taacgattaa agtaaattac
    32041 caaaccactt tccaaaagaa ggaagcaaaa aactagtata aacagaagag agagcgaaat
    32101 gctctttttt cgtttctaaa actactttca gtccatcatc ctaaaagtaa agaatctaaa
    32161 ttcactttct atttaccctt ctttcttgca ttgattacat agatatgcta cagttgtggt
    32221 aacgattaca aaataaaagg agcatgctat gaaaaatcca gctttgctag aagaaattaa
    32281 gacctataga ggaagggatg aggttccgga agactttgat gatttctggg atggggaagt
    32341 gaaaaatgtt tccacgcttc catcctacca cttggaggaa agagatttcc acattcctca
    32401 agtcaagtgc tatgagttaa catttgaagg aagcaagaaa ggaaaggtct atgcacgcat
    32461 tgttcttcca aagagtgagg agaaggttcc actaatcttc cattttcatg gttatatggg
    32521 acgtggctgg gactgggccg acatgctggg cttcaccgta gctggttacg gcgttgtttc
    32581 catggatgtg cggggccagt caggttactc acaagacggc ttgcgttctc ctttaggaaa
    32641 taccgtgaag gggcatatta tccgtggtgc tgtggaaggt cgggaccacc tcttttataa
    32701 ggatgtttat ctggatattt accagttggt cgaaattgtt gctagtctgt ctcaggttga
    32761 tgagaagcgt ctttctagct atggtgcctc acaaggaggg gctctagctc tagttgcagc
    32821 agcgctcaat cctcgaattc agaaaacagt tgccatttat cccttcttgt cagacttcag
    32881 acgggtgatt gagattggta atactagcga ggcttacgac gaacttttcc gttatttcaa
    32941 gtttcacgac cccttccatg aaacagagga ggaaatcatg gcgacccttg cctatatcga
    33001 tgtcaaaaat cttgcccatc gtatccaagg tgaggttaag atgattacgg gcttggacga
    33061 cgatgtttgc tatcccatta cccagtttgc gatttataat cgtctgacct gcgataaaac
    33121 ctatcgcatc atgcctgagt atgctcacga agccatgaat gtatttgtca atgaccaagt
    33181 ctacaactgg ctctgtggaa gtgagattcc ttttaaatat ctaaaataag gagtcgactc
    33241 taagcacaaa atcttaaaaa ttacaaacac gcatagtatc aggggattaa gaaaacttga
    33301 tactatgcgt tttatcatgg aaatatagta aaatgaaaca agaacaggac aaatcgatca
    33361 ggacagtcaa atcgatttct aacaatgttt tagaagtaga tgtgtactat tctagtttca
    33421 atctattgta tttataaaat tttttgttgc tagatttgtc aaattgctta aaataatttt
    33481 tttcagaaag caaaagccga tacctatcga gtagggtagt tcttgctatc gttaggcttg
    33541 tctgtaggtg ttaatacttt tcaaaaatct cttcaaacca cgtcagcttc gccttgccgt
    33601 atatatgtta ctgacttcgt cagttctatc tgccacctca aaacggtgtt ttgagctgac
    33661 ttcgtcagtt ctatctgcca cctcaaaacg gtgttttgag ctgactttgt cagtcttatc
    33721 tacaacctca aaacagtgtt ttgagcatca tgcggctagc ttcttagttt gctctttgat
    33781 tttcattgag tataaaaaca gatgagtttc tgttttcttt ttatggacta taaatgttca
    33841 gctgaaacta ctttcaagga cattattata taaaagaatt ttttgaaact aaaatctact
    33901 atattacact atattgaaag cgttttaaaa atgaggtata ataaatttat taacacttat
    33961 aaaaagtgat agaatctatc tttatgtata tttaaagata gattgctgta aaaatagtag
    34021 tagctatgcg aaataacaga tagagagaag ggattgaagc ttagaaaagg ggaataatat
    34081 gatatttaag gtattcaaga caaaaaagca gagaaaaaga caagttgaac tacttttgac
    34141 agtttttttc gacagttttc tgattgattt atttcttcac ttatttggga ttgtcccctt
    34201 taagctggat aagattctga ttgtgagctt gattatattt cccattattt ctacaagtat
    34261 ttatgcttat gaaaagctat ttgaaaaagt gttcgataag gattgagcag gaagtatggt
    34321 gtaaatagca taagctgatg tccatcattt gcttataaag agatatttta gtttaattgc
    34381 agcggtgtcc tggtagataa actagattgg caggagtctg attggagaaa ggagagggga
    34441 aatttggcac caatttgaga tagtttgttt agttcatttt tgtcatttaa atgaactgta
    34501 gtaaaagaaa gttaataaaa gacaaactaa gtgcattttc tggaataaat gtcttatttc
    34561 agaaatcggg atataaatat agagaggatc agtatgaatc ggagtgttca agaacgtaag
    34621 tgtcgttata gcattaggaa actatcggta ggagcggttt ctatgattgt aggagcagtg
    34681 gtatttggaa cgtctcctgt tttagctcaa gaaggggcaa gtgagcaacc tctggcaaat
    34741 gaaactcaac tttcggggga gagctcaacc ctaactgata cagaaaagag ccagccttct
    34801 tcagagactg aactttctgg caataagcaa gaacaagaaa ggaaagataa gcaagaagaa
    34861 aaaattccaa gagattacta tgcacgagat ttggaaaatg tcgaaacagt gatagaaaaa
    34921 gaagatgttg aaaccaatgc ttcaaatgat cagagagttg atttatcaag tgaactagat
    34981 aaactaaaga aacttgaaaa cgcaacagtt cacatggagt ttaagccaga tgccaaggcc
    35041 ccagcattct ataatctctt ttctgtgtca agtgctacta aaaaagatga gtacttcact
    35101 atggcagttt acaataatac tgctactcta gaggggcgtg gttcggatgg gaaacagttt
    35161 tacaataatt acaacgatgc acccttaaaa gttaaaccag gtcagtggaa ttctgtgact
    35221 ttcacagttg aaaaaccgac agcagaattg ccaaatggtc gagttcgcct ctacgtaaac
    35281 ggggtattat ctcgaacaag tctgaaatct ggcaatttca ttaaagatat gccagatgta
    35341 acgcatgtgc aaatcggagc aaccaagcgt gccaacaata cggtttgggg gtcaaatcta
    35401 cagattcgga atctcactgt gtataatcgt gctttaacac cagaagaggt acaaaaacgt
    35461 agtcaacttt ttaaacgctc agatttagaa aaaaaactac ctgaaggagc ggctttaaca
    35521 gagaaaacgg acatattcga aagcgggcgt aacggtaaac caaataaaga tggaatcaag
    35581 agttatcgta ttccagcact tctcaagaca gataaaggaa ctttgatcgc aggtgcagat
    35641 gaacgccgtc tccattcgag tgactggggt gatatcggta tggtcatcag acgtagtgaa
    35701 gataatggta aaacttgggg tgaccgagta accattacca acttacgtga caatccaaaa
    35761 gcttctgacc catcgatcgg ttcaccagtg aatatcgata tggtgttggt tcaagatcct
    35821 gaaaccaaac gaatcttttc tatctatgac atgttcccag aagggaaggg aatctttgga
    35881 atgtcttcac aaaaagaaga agcctacaaa gaaatcgatg gaaaaaccta tcaaatcctc
    35941 tatcgtgaag gagaaaaggg agcttatacc attcgagaaa atggtactgt ctatacacca
    36001 gatggtaagg cgacagacta tcgcgttgtt gtagatcctg ttaaaccagc ctatagcgac
    36061 aagggtgatc tatacaaggg tgaccaatta ctaggcaata tctacttcac aacaaacaaa
    36121 acttctccat ttagaattgc caaggatagc tacctatgga tgtcctacag tgatgacgac
    36181 gggaagacat ggtcagctcc tcaagatatt actccgatgg tcaaagccga ttggatgaaa
    36241 ttcttgggtg taggtcctgg aacaggaatt gtacttcgga atgggcctca caagggacgg
    36301 attttgatac cggtttatac gactaataat gtatctcact taaatggctc gcaatcttct
    36361 cgtgtcatct attcagatga tcatggaaaa acttggcatg ctggagaagc ggtcaacgat
    36421 aaccgtcagg tagacggtca aaagatccac tcttctacga tgaacaatga acgtgcgcaa
    36481 aatacagaat caacggtggt acaactaaac aatggagatg ttaaactctt tatgcgtggt
    36541 ttgactggag atcttcaggt tgctacaagt aaagacggag gagtgacttg ggagaaggat
    36601 atcaaacgtt atccacaggt taaagatgtc tatgttcaaa tgtctgctat ccatacgatg
    36661 cacgaaggaa aagaatacat catcctcagt aatgcaggtg gaccgaaacg tgaaaatggg
    36721 atggtccact tggcacgtgt cgaagaaaat ggtgagttga cttggctcaa acacaatcca
    36781 attcaaaaag gagagtttgc ctataattcg ctccaagaat taggaaatgg ggagtatggc
    36841 atcttgtatg aacatactga aaaaggacaa aatgcctata ccctatcatt tagaaaattt
    36901 aattgggact ttttgagcaa agatctgatt tctcctaccg aagcgaaagt gaagcgaact
    36961 agagagatgg gcaaaggaga gatgggcaaa ggagttattg gcttggagtt cgactcagaa
    37021 gtattggtca acaaggctcc aacccttcaa ttggcaaatg gtaaaacagc gactttccta
    37081 acccagtatg atagcaagac cttgttattt gcagtagata aggaagatat cggacaggaa
    37141 attattggta tagctaaagg aagcatcgaa agtatgcata atcttcctgt aaatctagca
    37201 ggtgccagag ttcctggcgg agtaaatggt agcaaagcag cggtgcatga agttccagaa
    37261 tttacagggg gagttaatgg tacagagcca gctgttcatg aaatcgcaga gtataaggga
    37321 tctgattcgc ttgtaactct tactacaaaa gaagattata cttacaaagc tcctcttgct
    37381 cagcaggcac ttcctgaaac aggaaacaag gagagtgacc tcctagcttc actaggacta
    37441 atagctttct tccttggtct gtttacgcta gggaaaaaga gagaacaata agagaagaat
    37501 tctaaacatt tgattttgta aaaatagaag gagatagcag gttttcaagc ctgctatctt
    37561 tttttgatga cattcaggct gatacgaaat cataagaggt ctgaaactac tttcagagta
    37621 gtctgttcta taaaatatag tagattgaaa taagatgtga acaactctat caggaaagtc
    37681 aaattaattt atagaaaaat tttagcagtc aaggtgtact gttatatatt caatatatta
    37741 tgcgactatt aaccttgtct tctcctaaaa ttgactttct tgttttctta tcttgtccac
    37801 tcgaaacaag tattgtaaga atttgattat ttttgaaagt acttttaata tacttgatat
    37861 agttaaaaaa gatttgaaac taaattccaa attagaaaaa gacttgaaat actaaaaaaa
    37921 aaaaagtata ctctaattga aaacggtaac aaaactaatt tagagaatga aatatagagt
    37981 atttctctct taaaagtttt tggtgaaacg agatgtagaa aggagattta gccaaagagt
    38041 ctattagtgc tagaataata gattagaatt attttagaaa aacgaagtga gcagcttata
    38101 aattcaagtc cccaaataga ttcatactag tatcttttgc aaaaaataaa gggcgacttc
    38161 cttcatgaat atcaatttca tctataagga aggtagctaa ttgaactaac ttatttattc
    38221 tgtttgtcgc tagaaaaatc agacctcctt gtgaagattg aggagatact gaatgaaaat
    38281 caaagaagaa actagcaagc tagtagcaga tttcccaaaa caccgctttg aggttgtaga
    38341 taagactgac ctatataatc caaggtgaag cgactgtggt ttgaagagat tttcaaagag
    38401 tataggctag agagtagtgt ttttatgtcc ttctagtaga aaatgctaga cagaagaatg
    38461 gggaacttgg ataggaaaaa tagattgaga aaggaggtta gaagagatga ttattacaaa
    38521 aattagccgt ttaggaactt atgtgggagt caatccacat tttgcaacat taatagattt
    38581 tctagaaaaa acaggactag aaaatttaac agaaggttcg attgctatcg atggtaatcg
    38641 attgtttggg aattgcttta cttatctagc agatggtcaa gcaggggctt tctttgaaac
    38701 acaccaaaaa tatttggata ttcatttagt tttggaaaac gaagaagcca tggctgttac
    38761 atcgccggaa aatgtaagcg ttacccaaga atatgatgaa gagaaagata ttgaattata
    38821 cacagggaaa gtggaacagt tggttcattt gagagctggt gaatgcctca tcacttttcc
    38881 agaagattta catcaaccca aggttcgtat aaatgatgaa cctgtgaaaa aagttgtctt
    38941 taaagttgcg atttcttaat gtagaaagag aagaacgatg aaaaaaatga gaaagttttt
    39001 atgtctagct ggaattgcgc tagcggctgt tgccttggta gcttgttcag gaaaaaaaga
    39061 agctacaact agtactgaac caccaacaga attatctggt gagattacaa tgtggcactc
    39121 ctttactcaa ggaccccgtt tagaaagtat tcaaaaatca gcagatgctt tcatgcaaaa
    39181 gcatccaaaa acgaaaatca agattgaaac attttcttgg aatgacttct atactaaatg
    39241 gactacaggt ttagcaaatg gaaatgtgcc agatatcagt acagctcttc ctaaccaagt
    39301 aatggaaatg gtcaactcag atgctttggt tccgctaaat gattctatca agcgtattgg
    39361 acaagataaa tttaacgaaa ctgccttaaa tgaagcaaaa atcggagatg attactactc
    39421 tgttcctctt tattcacatg cacaagtcat gtgggttaga acagatttgt taaaagaaca
    39481 taatattgag gttcctaaaa cttgggatca actctatgaa gcttctaaaa aattgaaaga
    39541 agctggagtt tatggcttgt ctgttccgtt tggaacaaat gacttaatgg caacacgttt
    39601 cttgaacttc tacgtacgta gtggtggagg aagcctctta acaaaagatc ttaaagcaga
    39661 cttgacaagc caacttgctc aagatggtat taaatactgg gttaaattgt ataaagaaat
    39721 ctcacctcaa gattctttga actttaatgt ccttcaacaa gctaccttgt tctatcaagg
    39781 aaaaacagca tttgacttta actctggctt ccatatcgga ggaattaatg ccaacagtcc
    39841 tcaattgatt gattcgattg atgcttatcc tattccaaaa atcaaagagt ctgataaaga
    39901 ccaaggaatt gaaacctcaa acattccaat ggttgtttgg aaaaattcaa aacatccaga
    39961 agttgctaaa gcattcttag aagcacttta taatgaagaa gactacgtta aattccttga
    40021 ttcaactcca gtaggtatgt tgccaactat taaggggatt agcgattctg cagcctataa
    40081 agaaaatgaa actcgtaaga aatttaaaca tgctgaagaa gtaattactg aagctgttaa
    40141 aaaaggtact gctattggtt atgaaaatgg accaagtgta caagctggta tgttgactaa
    40201 ccaacacatt attgaacaaa tgttccaaga tatcattaca aatggaacag atcctatgaa
    40261 agcagcaaaa gaagcagaaa aacaattaaa cgatttattt gaggctgttc agtagatgta
    40321 aaagactaga aaataggtgg gctagtgatc tgaaaagctc tagcccaatc ttgtaaaaga
    40381 agggagaagg agaatggtta aagaacgtaa tttaactcgc tggatatttg ttttgccagc
    40441 tatgattatc gtaggattac tctttgttta tccgtttttc tcgagtattt tttatagctt
    40501 taccaataag catttgatta tgcctaatta taaatttgtt ggtttggcta actataaagc
    40561 tgtgctatca gatcccaact tctttaatgc gttctttaat tcaattaagt ggaccatttt
    40621 ctcattagtt ggtcaagttt tagtagggtt tgtattggct ttagctcttc acagagtacg
    40681 ccacttcaag aaattatata ggaccttatt gattgttcct tgggcatttc ctaccatcgt
    40741 tattgccttc tcttggcagt ggattctaaa cggggtttat ggctacttac ctaatctaat
    40801 cgtaaaatta ggtttaatgg aacatacacc tgcatttttg acagatagta catgggcatt
    40861 cctatgtttg gtgtttatca acatttggtt tggagcacca atgattatgg ttaatgtgct
    40921 ttcagctttg caaacagtac cagaagaaca atttgaggct gctaagatag atggtgcttc
    40981 aagttggcag gtgttcaagt ttatcgtctt tccacatatt aaagtggttg taggacttct
    41041 agttgttttg agaactgtat ggatctttaa taactttgac attatctacc tcattactgg
    41101 tggtggacca gccaatgcta caacgacgct tccaattttt gcttacaacc tgggctgggg
    41161 aactaaattg ttgggtcgtg cttcagcagt tacagtattg ctctttatct tcttggtggc
    41221 gatttgcttt atctactttg ctatcatcag taagtgggaa aaggagggta gaaaataatg
    41281 aagaagaaat ccagtattta tttagatatt ctctcacatg tacttttagt tggtgcgacc
    41341 atcgttgcag ttttcccatt ggtatggatt atcatatctt ctgtcaaagg gaaaggggaa
    41401 ttaactcagt atccaacacg attttggcct gaacagttta cattagatta tttcactcat
    41461 gttatcaacg atttgcactt cattgataac attcgaaaca gtttaatcat tgccttggct
    41521 acaaccctca ttgcgattat tatttctgct atggcagcct atggtattgt tcgattcttt
    41581 cctaaattgg gagcaatcat gtcgagacta ctcgtcatta cctacatttt cccaccaatt
    41641 ttgttagcaa ttccctattc aattgccatt gctaaagttg ggttaacaaa tagtttattt
    41701 ggcttgatga tggtttatct atcttttagt gttccatatg cagtttggct cttagttgga
    41761 tttttccaaa cagttccaat tggaattgaa gaagcggcta gaattgatgg tgcaaataaa
    41821 tttgttacgt tttataaagt tgtgctaccg attgtagcac caggtattgt agcaacagct
    41881 atttatacat ttatcaatgc ttggaatgaa ttcctgtatg ccttgatttt gattaacaat
    41941 acaggaaaga tgacagtagc agtagccctt cgttcactta atggttcaga aatactagac
    42001 tggggagata tgatggcagc gtctgttatt gtagttcttc catcaattat tttcttctct
    42061 atcatccaaa ataagattgc aagtggatta tcagaaggat ctgtgaagta gacgaaagaa
    42121 ggaaaaaaat gaataaaaga ggtctttatt caaaactagg aatttctgtt gtaggcatta
    42181 gtcttttaat gggagtcccc actttgattc atgcgaatga attaaactat ggtcaactgt
    42241 ccatatctcc tatttttcaa ggaggctcat atcaactgaa caataagagt atagatatca
    42301 gctctttgtt attagataaa ttgtctggag agagtcagac agtagtaatg aaatttaaag
    42361 cagataaacc aaactctctt caagctttgt ttggcctatc taatagtaaa gcaggcttta
    42421 aaaataatta cttttcaatt ttcatgagag attctggtga gataggtgta gaaataagag
    42481 acgcccaaaa gggaataaat tatttatttt ctagaccagc ttcattatgg ggaaagcata
    42541 aaggacaggc agttgaaaat acactagtat ttgtatctga ttctaaagat aaaacataca
    42601 caatgtatgt taatggaata gaagtgttct ctgaaacagt tgatacattt ttgccaattt
    42661 caaatataaa tggtatagat aaggcaacac taggagctgt taatcgtgaa ggcaaggaac
    42721 attacctcgc aaaaggaagt attgatgaaa tcagtctatt taacaaagca attagtgatc
    42781 aggaagtttc aactattccc ttgtcaaatc catttcagtt aattttccaa tcaggagatt
    42841 ctactcaagc taactatttt agaataccga cactatatac attaagtagt ggaagagttc
    42901 tatcaagtat tgatgcacgt tatggtggga ctcatgattc taaaagtaag attaatattg
    42961 ccacttctta tagtgatgat aatgggaaaa cgtggagtga gccaattttt gctatgaagt
    43021 ttaatgacta tgaggagcag ttagtttact ggccacgaga taataaatta aagaatagtc
    43081 aaattagtgg aagtgcttca ttcatagatt catccattgt tgaagataaa aaatctggga
    43141 aaacgatatt actagctgat gttatgcctg cgggtattgg aaataataat gcaaataaag
    43201 ccgattcagg ttttaaagaa ataaatggtc attattattt aaaactaaag aagaatggag
    43261 ataacgattt ccgttataca gttagagaaa atggtgttgt ttatgatgaa acaactaata
    43321 aacctacaaa ttatactata aatgataagt atgaagtttt ggagggagga aaatctttaa
    43381 cagtcgaaca gtattcggtt gattttgata gtggctcttt aagagaaagg cataatggaa
    43441 aacaggttcc tatgaatgtt ttctacaaag attcgttatt taaagtgact cctactaatt
    43501 atatagcaat gacaactagt cagaatagag gagagagttg ggaacaattt aagttgttgc
    43561 ctccgttctt aggagaaaaa cataatggaa cttacttgtg tcccggacaa ggtttagcat
    43621 taaaatcaag taacagattg atttttgcaa catatactag tggagaacta acctatctca
    43681 tttctgatga tagtggtcaa acatggaaga aatcctcagc ttcaattccg tttgaaaatg
    43741 caacagcaga agcacaaatg gttgaactga gagatggtgt gattagaaca ttctttagaa
    43801 ccactacagg taagatagct tatatgacta gtagagattc tggagaaaca tggtcggaag
    43861 tttcgtatat taatggaatc caacaaactt catatggcac acaagtatct gcaattaaat
    43921 actctcaatt aattgatgga aaagaagcag tcattttgag tacaccaaat tctagaagtg
    43981 gccgtaaggg aggccaatta gttgtcggtt tggtcaataa agaagatgat agtattgatt
    44041 ggagatacca ctatgatatt gatttgcctt cgtatggtta tgcctattct gcgattacag
    44101 aattgccaaa tcatcacata ggtgtactgt ttgaaaaata tgattcgtgg tcgagaaatg
    44161 aattgcattt aagcaatgta gttcagtata tagatttgga aattaatgat ttaacaaaat
    44221 aaaggagaaa aacatggtta aatacggtgt tgttggaaca gggtattttg gagctgaatt
    44281 ggctcgctac atgcaaaaga atgatggagc agagattact cttctctatg atccagataa
    44341 tgcagaggcg attgcagaag aattgggagc aaaagtagca agttccttag atgagttggt
    44401 ttctagcgat gaagtagatt gtgttatcgt cgcaactcca aataatcttc ataaggaacc
    44461 ggttattaag gctgcacagc atggtaaaaa tgttttctgt gaaaaaccaa ttgcgctttc
    44521 ttatcaagat tgtcgcgaga tggtagatgc gtgtaaagaa aacaatgtaa cctttatggc
    44581 aggacatatt atgaatttct ttaatggtgt tcatcatgca aaagaactca ttaatcaagg
    44641 agttatcgga gacgttctat attgtcatac agctcgtaat ggttgggaag aacaacaacc
    44701 gtcagtgtca tggaaaaaaa ttcgtgaaaa atcaggtggt cacttgtatc accacatcca
    44761 tgaattggat tgcgttcaat tccttatggg gggcatgcct gaaactgtaa ccatgacagg
    44821 tggaaatgtg gcccatgaag gtgaacattt cggtgatgaa gatgatatga tttttgtcaa
    44881 tatggaattt tctaataagc gttttgcctt gttagaatgg ggttcagctt atcgttgggg
    44941 tgaacattat gtcttaatcc aaggaagcaa aggtgccatc cgcttagatt tattcaactg
    45001 taaaggaact cttaagctag atgggcaaga aagctatttc ttgattcacg aatcgcaaga
    45061 agaagatgat gatcggactc gtatctatca tagtacagag atggatggag caattgctta
    45121 tggtaaacca ggtaaacgta ctccattatg gctatcatct gtcattgata aagaaatgcg
    45181 ctatctgcat gagattatgg aaggagcccc agtatcagaa gaatttgcaa aacttttgac
    45241 aggagaagct gccctagaag caattgctac tgcagatgct tgtacccagt ctatgtttga
    45301 agatcgcaaa gtaaaattgt cagaaattgt aaaataaatt ttggtattct cctatttata
    45361 ggtcgacttg ctcctctgaa agtactttta gaggagctgt ttgactttgc tagtttttga
    45421 aactgaaatc tattatacta caaactattg aaagcgtttt aattttaagg tataataatc
    45481 tcatagaaat aaagaaaagg aggaaagagg atg
//
LOCUS       DAVHBD010000014        43544 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000014 DAVHBD010000000
VERSION     DAVHBD010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.014"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..992)
                     /locus_tag="VVK04_000782"
     CDS             complement(<1..992)
                     /locus_tag="VVK04_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HEU3989467.1"
                     /translation="MILIVTLNPSIELLYFEKNFTLGAHNRFQNSTIMAAGKGINCAR
                     ALSYLGINATALTLVGGKSGEFFKQHLAQEKFHPLYIPIDGETRHSITIMHNDNIHTE
                     IVEAGPKVDQGLKSQIFDTLLQVIKEKNISIVSLNGSVHSDDRDFYNDLIQFLRENTD
                     STLKILADFSQTALQKIVNDAIHLPDFIKPNMEEFCQLTGLSVTTKQEILDYLMDKPS
                     PIPYTLVSCGEQGAIAQFNGKLYDVTAPSINLVNPTGSGDSTVAGAIYAFEQNLSDED
                     IIRYATASGTANAMENGVGVARKEIVEKLIPQVIIKEIHKSWSLGQNSSRPQKS"
     gene            complement(1009..1749)
                     /locus_tag="VVK04_000783"
     CDS             complement(1009..1749)
                     /locus_tag="VVK04_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU3989468.1"
                     /translation="MKINRKKEILNLLENSDVISYQELAQSLHVSTMTIRRDVSELEK
                     ENLVIKEHGGVRKVTFNTKTTDEKRLLYPEEKDYIAQLAANLIEPNSVIYLSAGTTIL
                     ALAKHLKNQHKHIITNSLFTFNWLNEHNFENILLTGGEFVSKTEEFHGEHAERLVKDF
                     LIDYAFLATNGLVDDHLTAFSSFGGRLQSIAMNQSRKVYLLADHSKFGLNDSYIYGKL
                     SQIDAIISDDKLDPETKKYYQQFTDIIN"
     gene            1972..2430
                     /locus_tag="VVK04_000784"
     CDS             1972..2430
                     /locus_tag="VVK04_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU3989469.1"
                     /translation="MYKMMLQPDLIRLDCSVSKHTELFQMVGKELEEKGYVTNQYLEA
                     LLEREQRFPTGLKTRFLNIALPHTDPEVIKEPFIFVVRNDKDLNMLQMGDNSDTPCQN
                     FLFLGIKDPKSQVGLLAKLMEIFSQEEFVQNFAQIKDGSEMYELLNQQLS"
     gene            2458..2760
                     /locus_tag="VVK04_000785"
     CDS             2458..2760
                     /locus_tag="VVK04_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU3989470.1"
                     /translation="MARKLIVACGSGVATSTTIAEKIKTRFEDDGIDYPVEAVDYKSI
                     LNELPQASIYVYIAMPEQEVLDEAERLGVDVYPGVPFLTGMGADNVYEQIVESTNK"
     gene            2792..4141
                     /locus_tag="VVK04_000786"
     CDS             2792..4141
                     /locus_tag="VVK04_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU3989471.1"
                     /translation="MEIFQNVIQWILNLGSAIFVPLIIFVLGLMVGMNIKKAFISAIT
                     LGVAFTGMGMIIGFMSNAVSPASEALAINTGISLPALDLGWTGAASIVWSWGYAFAFF
                     AVQIIINIIMLSFNWTKTLNVDMWNVWGKALTGYLVYYVSGQLWAGFLVAGLQVVLEL
                     KLGDMFQKHIEDLTGIPLVTVTHGMILSAVFMLPVNKLMDKIPFLNKKADTNALRKKL
                     GIFSENSVMGFIIGVLLGFAGAYSVSNSLNLGIQVATAMALFPMVSKLFMQALSPLAE
                     SMSEFMKKRFNDREVFIGMDWPLLAGRSEVWVTLILMVPFFIGYSLILPGNAVLPIAG
                     VLNYSIAVGGLLLTGGNLARMMILGIIYLPLCLYSATYFAPILTGLANKTGAVEVEAG
                     KLITWSSLESPELRILFAESFNGNILAIGGAVAFLLLFVWLYKTMVTQEVPSKRYEN"
     gene            4131..4374
                     /locus_tag="VVK04_000787"
                     /pseudo
     CDS             4131..4374
                     /locus_tag="VVK04_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379223.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4371..5123
                     /locus_tag="VVK04_000788"
     CDS             4371..5123
                     /locus_tag="VVK04_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEU3989472.1"
                     /translation="MTSGKILFEQERRAMAEAIELTFYRKNTNTAGGNFSFKTTDVNG
                     KEYIIMTPSMMSETYHGKVSAAQVLVLDLETQEVVAGEGKPTREINLHFACYETNPDI
                     KCVFHAHAPNAMFWATSHLDMPNLSEATQKVEYIKVLDFAPNTTPELAEIVRQELLEF
                     GNKLPKEYLLDSHGILVLTPGADGEEALNKALQIIDTVEWNAEIAYKQTIFQKLGILD
                     GYYSKGRKIGDIDDLINHRPIWNQEKKDEGFE"
     gene            complement(5233..6234)
                     /gene="galR"
                     /locus_tag="VVK04_000789"
     CDS             complement(5233..6234)
                     /gene="galR"
                     /locus_tag="VVK04_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU3989473.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLRHTCIITDFYTAI
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTKLTLRESTLP"
     gene            6398..7576
                     /locus_tag="VVK04_000790"
     CDS             6398..7576
                     /locus_tag="VVK04_000790"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU3989474.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEVDQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLVDLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            7595..9076
                     /locus_tag="VVK04_000791"
     CDS             7595..9076
                     /locus_tag="VVK04_000791"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU3989475.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            9146..9550
                     /locus_tag="VVK04_000792"
     CDS             9146..9550
                     /locus_tag="VVK04_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU3989476.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            9731..10495
                     /locus_tag="VVK04_000793"
     CDS             9731..10495
                     /locus_tag="VVK04_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEU3989477.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            10492..10953
                     /locus_tag="VVK04_000794"
     CDS             10492..10953
                     /locus_tag="VVK04_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HEU3989478.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSESMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(11004..12266)
                     /locus_tag="VVK04_000795"
     CDS             complement(11004..12266)
                     /locus_tag="VVK04_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU3989479.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKIANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(12266..12847)
                     /locus_tag="VVK04_000796"
     CDS             complement(12266..12847)
                     /locus_tag="VVK04_000796"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU3989480.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(13247..13342)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(13725..13964)
                     /locus_tag="VVK04_000797"
     CDS             complement(13725..13964)
                     /locus_tag="VVK04_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU3989481.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(13964..14107)
                     /locus_tag="VVK04_000798"
     CDS             complement(13964..14107)
                     /locus_tag="VVK04_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU3989482.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(14119..14946)
                     /gene="xth"
                     /locus_tag="VVK04_000799"
     CDS             complement(14119..14946)
                     /gene="xth"
                     /locus_tag="VVK04_000799"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU3989483.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            15080..15535
                     /locus_tag="VVK04_000800"
                     /pseudo
     CDS             15080..15535
                     /locus_tag="VVK04_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            15688..15984
                     /locus_tag="VVK04_000801"
     CDS             15688..15984
                     /locus_tag="VVK04_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU3989484.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            16190..17935
                     /locus_tag="VVK04_000802"
     CDS             16190..17935
                     /locus_tag="VVK04_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3989485.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPELPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLSLSAVVEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILEPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            17925..19676
                     /locus_tag="VVK04_000803"
     CDS             17925..19676
                     /locus_tag="VVK04_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989486.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQKISDDQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            19849..20541
                     /locus_tag="VVK04_000804"
     CDS             19849..20541
                     /locus_tag="VVK04_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU3989487.1"
                     /translation="MLKWEDLPVEMKSSEVESYYHLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            20584..21810
                     /locus_tag="VVK04_000805"
     CDS             20584..21810
                     /locus_tag="VVK04_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU3989488.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVNRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            22941..25100
                     /gene="pfbA"
                     /locus_tag="VVK04_000806"
     CDS             22941..25100
                     /gene="pfbA"
                     /locus_tag="VVK04_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU3989489.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIIIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            25084..25380
                     /locus_tag="VVK04_000807"
     CDS             25084..25380
                     /locus_tag="VVK04_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989490.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            25723..25935
                     /locus_tag="VVK04_000808"
     CDS             25723..25935
                     /locus_tag="VVK04_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989491.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
     gene            25993..26634
                     /locus_tag="VVK04_000809"
     CDS             25993..26634
                     /locus_tag="VVK04_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU3989492.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNIDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QILQNNEILKKIISEIKILHEVIELHMNRAISCYREEQSGCLDMVVIQKQNEIEELSI
                     NMEKKIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            26647..28122
                     /gene="galT"
                     /locus_tag="VVK04_000810"
     CDS             26647..28122
                     /gene="galT"
                     /locus_tag="VVK04_000810"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU3989493.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNDKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            28135..29115
                     /gene="galE"
                     /locus_tag="VVK04_000811"
     CDS             28135..29115
                     /gene="galE"
                     /locus_tag="VVK04_000811"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU3989494.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            29326..29985
                     /locus_tag="VVK04_000812"
     CDS             29326..29985
                     /locus_tag="VVK04_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU3989495.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEVSAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            30010..31077
                     /locus_tag="VVK04_000813"
     CDS             30010..31077
                     /locus_tag="VVK04_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU3989496.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            31181..32191
                     /locus_tag="VVK04_000814"
     CDS             31181..32191
                     /locus_tag="VVK04_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989497.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            32203..33894
                     /locus_tag="VVK04_000815"
     CDS             32203..33894
                     /locus_tag="VVK04_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU3989498.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            33897..34607
                     /locus_tag="VVK04_000816"
     CDS             33897..34607
                     /locus_tag="VVK04_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU3989499.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            34703..35070
                     /locus_tag="VVK04_000817"
                     /pseudo
     CDS             34703..35070
                     /locus_tag="VVK04_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            35178..36179
                     /locus_tag="VVK04_000818"
     CDS             35178..36179
                     /locus_tag="VVK04_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU3989500.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            36786..36860
                     /locus_tag="VVK04_000819"
                     /pseudo
     CDS             36786..36860
                     /locus_tag="VVK04_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            37319..38680
                     /gene="trpE"
                     /locus_tag="VVK04_000820"
     CDS             37319..38680
                     /gene="trpE"
                     /locus_tag="VVK04_000820"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU3989501.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            38677..39243
                     /locus_tag="VVK04_000821"
     CDS             38677..39243
                     /locus_tag="VVK04_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU3989502.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDDRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            39254..40258
                     /gene="trpD"
                     /locus_tag="VVK04_000822"
     CDS             39254..40258
                     /gene="trpD"
                     /locus_tag="VVK04_000822"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU3989503.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            40255..41022
                     /gene="trpC"
                     /locus_tag="VVK04_000823"
     CDS             40255..41022
                     /gene="trpC"
                     /locus_tag="VVK04_000823"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU3989504.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVVQRIKELQIDKG"
     gene            41009..41608
                     /locus_tag="VVK04_000824"
     CDS             41009..41608
                     /locus_tag="VVK04_000824"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU3989505.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVSLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            41586..42809
                     /gene="trpB"
                     /locus_tag="VVK04_000825"
     CDS             41586..42809
                     /gene="trpB"
                     /locus_tag="VVK04_000825"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU3989506.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     NKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            42802..>43544
                     /locus_tag="VVK04_000826"
     CDS             42802..>43544
                     /locus_tag="VVK04_000826"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU3989507.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQV
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQ"
BASE COUNT        13585 a         7455 c         9339 g        13165 t
ORIGIN      
        1 tagctttttt gtggtcgaga actattttgt cccaggctcc atgatttatg gatttcttta
       61 ataataactt gagggattaa tttttccaca atttcttttc ttgcgactcc tacaccattt
      121 tccatagcat ttgcagttcc actagctgta gcatagcgaa tgatatcctc gtccgataag
      181 ttctgttcaa aagcatagat agctcctgct acagtagagt ctcctgaccc tgttggattg
      241 accaaattaa tggatggtgc agtgacgtcg tataacttac cgttaaactg ggcgatggct
      301 ccttgctctc cacaagacac tagagtgtat gggataggag aaggcttgtc catcaagtag
      361 tctaatattt cttgcttagt ggtgacagat aatcctgtta attggcaaaa ttcttccata
      421 tttggtttga taaagtcagg aaggtgtatt gcatcgttaa caattttttg tagggcagtt
      481 tgtgaaaaat cagctaatat ttttaatgta gaatcagtgt tttcacgtaa gaattgaatc
      541 aaatcattat agaaatccct atcatctgaa tgtacagagc catttaaaga gacgatgctg
      601 atattctttt ccttgataac ctgtaacaat gtatcaaaga tttgtgattt taaaccttgg
      661 tccacttttg ggcccgcctc aacaatttcc gtatgaatat tgtcattatg catgatggtt
      721 attgagtgac gagtctctcc gtcaatagga atatataagg ggtgaaactt ttcttgtgca
      781 agatgttgtt tgaaaaactc gccagattta ccaccgacta gggttagtgc agtggcattt
      841 attcccaaat aagagagggc acgagcacag ttgattcctt taccagcggc cataattgta
      901 gaattttgga aacgattatg agcacctagt gtaaagtttt tttcgaaata gagtaattcg
      961 atagatggat ttaatgtaac gatgagaatc atgggcagat acctttcttt agttaataat
     1021 atcggtaaac tgctgataat atttcttggt ttctggatct aatttgtcat ctgaaataat
     1081 agcatctatt tggctaagtt ttccataaat ataggaatcg tttaggccaa atttagaatg
     1141 atcagctagt aaataaactt ttctagattg attcatagca atagattgta aacgtccacc
     1201 aaaagatgaa aaagctgtta aatgatcatc aacgaggcca ttggttgcta agaatgcata
     1261 gtcgattaga aaatctttta ctagtctttc agcatgctca ccatggaact cttccgtttt
     1321 tgaaacaaac tctccgccag ttaggagtat attttcaaag ttgtgttcat ttagccaatt
     1381 aaaagtaaac aagctattcg ttataatatg cttatgttga tttttcagat gtttagcaag
     1441 tgctaaaata gtagttccag cgctaagata gatgacacta tttggctcaa ttaaattagc
     1501 agcaagttgc gcgatgtaat ctttttcttc aggataaagc agacgctttt catcagttgt
     1561 tttcgtattg aatgttactt ttcgaacacc gccgtgttct ttgataacta gattttcttt
     1621 ttctaattct gaaacatctc ttcgaatggt cattgttgag acgtgtaatg attgcgcaag
     1681 ttcctgatag gagatgacat cgctgttttc aagcaaattt aaaatttctt tttttctatt
     1741 aattttcaaa ataaaggttg ctcccctcag tgaattttat agtactatca taacataaaa
     1801 ttagaaaaga ttagaatcca ataagtttat aacaaaaaat atcaaaagat aacaaaaaat
     1861 aacaattaaa gcattgactt tttaaatgaa aacgcttata attacattat aacaaaaaat
     1921 aacagaatgt taacaataaa tttaacgttt ttttaaaaaa ggagttgtga tatgtataaa
     1981 atgatgttgc aaccggattt gatacggttg gactgtagtg tatcgaagca tacagaacta
     2041 ttccaaatgg ttggaaagga gttggaagaa aagggatatg taacaaatca atacttggag
     2101 gctctattag aaagggaaca gcgttttcct acaggcttaa aaacacgatt tttaaatatc
     2161 gcacttcccc acacagatcc agaagtcatc aaggagccat ttatttttgt tgttcgcaat
     2221 gataaagact taaatatgtt gcaaatgggt gataactctg atactccttg tcaaaacttt
     2281 ctgttcttag gtataaaaga tcctaagagc caggttggtc tcttagctaa actaatggaa
     2341 attttttctc aagaagaatt tgtacaaaac ttcgctcaaa taaaagatgg gtcggaaatg
     2401 tatgaattat taaatcaaca actatcataa acaaaagcct aaaaaggaga ataaaaaatg
     2461 gcaagaaaat taatcgtagc atgtggaagt ggtgtagcaa ccagtacaac aattgctgaa
     2521 aaaatcaaaa cacgctttga agatgacggt atcgactatc ctgtagaagc agtagattac
     2581 aaatcgatct taaatgaact accacaagca agtatctacg tctatattgc tatgccagaa
     2641 caagaagttt tggatgaagc cgagagactg ggggtagatg tttatccagg tgttccattc
     2701 ttaactggaa tgggtgcgga taacgtatat gagcaaattg ttgagtctac aaataaataa
     2761 aatataaaaa taaattaagg agaaaaaggt tatggaaatc tttcaaaatg ttattcagtg
     2821 gattttgaat ttaggatctg cgatttttgt accattgata attttcgttt taggtttaat
     2881 ggttggtatg aatattaaaa aagcctttat ttcagccatt actctcgggg ttgcctttac
     2941 aggtatggga atgatcattg gatttatgtc aaatgcggtg tcgccagctt ctgaggctct
     3001 agctataaat acaggaattt ctctcccagc tcttgacttg ggttggactg gtgcggcaag
     3061 tattgtatgg tcatggggtt atgccttcgc attctttgct gtacaaatca ttatcaatat
     3121 tattatgctc agtttcaact ggacaaagac tcttaatgtg gatatgtgga atgtttgggg
     3181 taaagcctta acaggatatc ttgtttacta tgtcagcggt cagttgtggg ctggtttcct
     3241 tgtggcggga ttacaagttg tgttagagct aaagcttgga gacatgttcc aaaaacatat
     3301 tgaggattta actggtattc cgctggtaac tgttacacat ggtatgattc tttccgcggt
     3361 attcatgttg cctgttaaca aattgatgga caaaattcca ttcttgaata aaaaagctga
     3421 tacaaatgct cttcgtaaaa aattgggtat cttctctgaa aactctgtaa tgggattcat
     3481 tattggtgtg cttctcggat ttgcaggtgc ctattctgta tctaattcct taaatttggg
     3541 tatccaagtt gcgactgcga tggcgctatt cccaatggta agtaaactct tcatgcaggc
     3601 cctttcacca ctggctgaat ctatgagcga attcatgaag aaacgcttta atgaccgtga
     3661 agtatttatt ggaatggact ggccattgtt agcaggtcgc tcagaagttt gggtaacgtt
     3721 aatcttgatg gtaccattct ttattggcta ttctcttatc ttgccaggaa atgcagtgct
     3781 cccaattgca ggtgtcttga actactctat cgctgtaggc ggactattgc tgacaggtgg
     3841 taacttggca cgtatgatga ttctaggtat tatttatctt ccgctttgtc tctacagtgc
     3901 tacttatttc gcaccaatct tgacagggtt ggccaataag accggagcag tcgaagttga
     3961 agctggtaaa ttgattactt ggtcatcact tgaatcgcca gaattgcgga ttctcttcgc
     4021 agaaagcttt aatggtaata ttttagccat cggaggggcg gttgctttcc tattactttt
     4081 tgtatggttg tacaaaacaa tggtaacaca agaagtaccg tcaaaacgtt atgaaaacta
     4141 gtaaaactct ttggtacagt ctcttatttg tagctcttgt cttatttttg ctaggtttaa
     4201 atagtggcca atatctttac aattttttag cgattatcat cagttttatc gtctataaat
     4261 atggctacag tgacttattt agagaatatg atgagaaaca acgtgcgaag agagacatct
     4321 gaaaaaatct atcatgcttt acgagaagga aaaaagaaag aggaaaataa atgacaagtg
     4381 gtaaaatttt atttgaacaa gaaagacgcg ctatggctga agccatcgaa ctgactttct
     4441 atcgcaaaaa caccaatact gctggaggaa atttctcctt taaaacgaca gatgttaatg
     4501 gtaaagaata catcattatg acaccgtcca tgatgtctga aacctatcac gggaaagtat
     4561 cggctgctca agtgttggtg ctggatttag aaactcaaga agtggttgct ggagaaggca
     4621 aaccgacacg cgaaatcaac cttcactttg cttgctatga aaccaaccca gatatcaaat
     4681 gtgttttcca tgctcatgca ccaaatgcaa tgttttgggc aactagccac ttagatatgc
     4741 caaacttatc tgaagctact caaaaagttg agtatatcaa agttttggat tttgccccaa
     4801 atactacacc tgaactggct gaaattgtac gtcaagaact cctagagttt ggcaacaaat
     4861 tgccaaaaga atacttacta gacagtcatg gtattttggt attgacaccg ggtgctgatg
     4921 gagaagaggc tttgaataaa gcccttcaga ttattgatac agttgaatgg aatgctgaaa
     4981 ttgcatacaa gcagacaatc ttccaaaagt taggaatttt ggatggttac tattctaaag
     5041 gtcgtaaaat tggagatatt gatgatttaa tcaatcatcg tccaatttgg aatcaagaaa
     5101 agaaagacga aggtttcgaa taaactattt gggaggagga taggcacgtg ctatcttcct
     5161 ttttaaaaaa gaaatcctaa tggatatttg agaatctcta ttaggatttt tggtcttatt
     5221 atattagttg agttatggca gagtactttc tcttaacgtc agtttggttc ccagcatggt
     5281 caggctagga attttgcgac cgtggaggac ttccttgtta agaatatcca tacctgctcg
     5341 ccccatttct tcagtataaa ctgtgatgct ggagagggga ggataaacct gcttggtcag
     5401 gctggtgtcg ttaaatgaaa tgaggctgac acggtctggt aggctgattc cagcttcttg
     5461 gagtgcacga agggcaccga tggctaaact atcgctggct gcgaaaaatg ctggtgggag
     5521 ttggtctccc aagttctgaa tggcttcctt catcaagtca tagccagact gggcagtaaa
     5581 gtttccttga aagaccagtt catcatgata gattcctttt gcttgactgt agtttctgaa
     5641 attttccagc cgcttatcct gaatgatttc ttcttggtca gttgtttctt caaggcctgt
     5701 tagaatcccg atacggtcca ttccttggct gaggaaataa tcgacaacct gttttatagc
     5761 agtgtaaaag tccgtaataa tacaagtatg cctcagggaa agtgtatcac tgtctagaaa
     5821 gaccaggggt ttttggtatt cttcaaaggc agaaatctga gctcggctaa attttccgat
     5881 gcagagaatc ccaatcactt cctcgcttaa ggtaaaagga tggtcattaa aatagcgcaa
     5941 gatatcatag tccaactctt gggctctttt ttctattcct aggcgaatct ggtagtagta
     6001 gaggtcgtcc agctcccctt gttcgctgac ccattggata atggcaatct tttgcttggg
     6061 tttgtgggac tcgcctgtct tgaggtgctt ggtgtagccc agctcttcag caacggttaa
     6121 aatacggtgt ctggtttctt ctgtaacaga taggctctgg tcgcggttga ggacgcggga
     6181 tacggtcgcg atagagacag aggctagctg tgcaatgtct tttaaggtag ccataaatcc
     6241 tccttgatta ggttagtata tcatattttt ctgcttttta ctgatagttt agtaaaattt
     6301 tagtaaaaag gattgacctt gggaaatccc ttggatacaa tagaagaaaa cgattacacg
     6361 ttaaggtggc ttaacggaca gtcaaaggag aaatcatatg acacaacatc ttactgctga
     6421 aactcttcgc aaagactttc ttgctgtttt tggtcaagaa gtagaccaaa cattcttttc
     6481 accaggtcgt atcaatttga ttggtgaaca cacagactac aacggtgggc acgtttttcc
     6541 tgctgctatt tccttgggaa cttacggtgc agctcgtaag cgtgacgacc aagtcttgcg
     6601 tttctactca gctaactttg aggacaaggg cattatcgaa gtgcctctcg ttgaccttaa
     6661 gtttgaaaaa gagcacaact ggaccaatta tccaaaaggt gtccttcatt tcttgcaaga
     6721 agctgggcac gtgattgaca aaggttttga tttttatgtt tatgggaata tcccaaatgg
     6781 tgctggtttg tcttcttcag catccttgga gctcttgaca ggagtcgtgg cagagcatct
     6841 ctttgattta aaactagacc gtttggattt ggttaaaatc ggaaagcaaa cagaaaataa
     6901 ctttatcgga gtaaattctg gcattatgga ccaatttgct attggtatgg gggctgacca
     6961 acgtgctatt tacttagata ccaatacttt agaatacgac ttggtgccac ttgatttgaa
     7021 ggacaatgtc gttgttatca tgaacaccaa caaacgccgt gaattggcgg actctaaata
     7081 caatgaacgt cgtgctgagt gtgaaaaagc agtggaagaa ttgcaagttg ccttggatat
     7141 tcagaccctg ggtgaattgg acgagtgggc cgttgaccaa tatagctatt tgattaaaga
     7201 tgaaaatcgt ttgaaacgtg ctcgccatgc tgtgcttgaa aaccaacgta cccttaaagc
     7261 tcaagcagcc cttcaagcag gtgatttgga aacatttggt cgtttgatga atgcgtcaca
     7321 cgtttctctg gagcatgatt atgaagtaac tggtttggaa ttggatactc ttgttcacac
     7381 agcttgggca caagaaggag ttctcggtgc tcgtatgaca ggggctggtt ttggtggctg
     7441 tgccattgcc ttggttcaaa aagatactgt tgaggccttt aaggaagctg taggcaaaca
     7501 ctacgaggaa gtagttggat acgctccaag cttctatatc gctgaagttg caggtggcac
     7561 tcgcgtcctt gactagtcaa aaggaggctc tatagtgatc ttagtagata aatttgtaac
     7621 acatgtcatt tctgaaagtt catttgagga aatggatcga atctacctga ccaaccgtgt
     7681 tttggcacga gtgggagaag gtgttttgga agttgagacc aatctggata aattgattga
     7741 cctcaaggac cagctagttg aggaagccgt tcgattagag atgattgagg atagtcagac
     7801 tgcgcgtgaa atccttggta ctgaactgat ggacttggtg actccttgtc cgagtcaggt
     7861 caatcgtgac ttctgggaag cctatgtcca ctctcctgag caagcgatag aggattttta
     7921 tcaactcagt cagaaaaatg attacatcaa actcaaggcc attgctaaaa atatcgctta
     7981 tcgtgttcca tctgattatg gagaacttga aattaccatc aatctctcta agcctgaaaa
     8041 ggatccgaaa gagattgcgg tagccaagtt ggtgcaagct agtaattatc ctcagtgtca
     8101 actttgttta gagaatgagg gttaccatgg tcgggtcaac cacccagctc gcagcaacca
     8161 ccggattatc cgttttgaaa tggttggtca ggaatggggg ttccagtatt cgccctatgc
     8221 ttactttaat gagcattgta tctttttaga tggccagcat cgtcccatgg ccattagtcg
     8281 tcagagtttt gaacgtctgt tggctatcgt agagcagttt ccaggatatt ttgctggatc
     8341 taatgccgac ctgccgattg tggggggctc tattctaact catgatcatt atcagggagg
     8401 ccgtcacgta tttcctatgg aattggctcc cttgcaaaag accttccgat ttgctggttt
     8461 tgagcaggtc aaggctggaa ttatcaagtg gccaatgtct gtcctacgct tgacttcgga
     8521 ttccaaagag gatttgatta acttagctga taagattttc caggaatggc gtcagtattc
     8581 agattctagt gtgcagattt tagcagagac agacgggaca ccgcatcaca ccatcacacc
     8641 aatagcgcgt aagcgtgatg gacagtttga gttggacttg gtcttgcgag acaatcagac
     8701 ttcagcagag catcctgatg gcatctatca tccccacaag gatgtccaac atatcaagaa
     8761 ggaaaatatc ggcttgattg aggtcatggg cttggcaatc ttgccaccac gtctgaaaga
     8821 agaagtagag caagtcgcta gctatcttgt aggagaagct gttacagttg ccgattatca
     8881 tcaggagtgg gcagaccaac tcaaatccca acatccagac ctaacggata aagaaaaagc
     8941 ccttgcaatc gtcaaggact ctgtgggtgc tatctttgtg cgtgtacttg aggatgcagg
     9001 agtctacaag cagacagaac aagggcagac agcctttatg cgctttgtgg aacaggtcgg
     9061 aatttcacta gactaggagc tttctccttg cacagtccta taaaaagtag tatcatagtg
     9121 tcgtttgaaa tatcaggagg aaacgatgaa agactttcat tttgacgcta tatctgcctt
     9181 tgaaaattac gaaattgaaa aaatgagaga tggtcacgtt gtggtgacga ccaaagtagt
     9241 gaactcgtcg ctcaactact atggcaatgc ccatggtggc tatctattca cgctatgtga
     9301 ccaaatcagt ggtttggtgg ttatctcgct gggacttgat ggggtgacac tccaatcctc
     9361 tatcaactac cttaaggcag gaaaactcga cgatgtattg accattaaag gagaatgtgt
     9421 ccatcaaggt cgtacaacct gtgtgatgga tgtggatatc accaatcaag agggcagaaa
     9481 tgtctgtaaa gcaaccttta ccatgtttgt cacaggccaa aggtctgagg aaagacgggt
     9541 aagtatataa agaaaggtga gtgggataaa tttatctcac tcatttttaa tttatgagat
     9601 atgttagaag gaaatataaa agagagtgat gaaatacaaa tgtaataggt acatatatgt
     9661 ggtatactag ttatagtaga ttttaattgc ttatatcgag tgagttctca tattagtgag
     9721 gaatttttaa atggaattac actttaattt agaattagta gaaacctata aaagtaatag
     9781 ccaaaaggca cgtatcttaa cggaggattg ggtttatcgt cagtcttatt gccctaattg
     9841 tgggaacaat cccttaaatc attttgaaaa taatcggcct gtagcagatt tttactgtaa
     9901 tcattgtagt gaggagtttg aactaaagag caaaaaagga aatttttcat caacaatcaa
     9961 tgatggtgct tatgcaacga tgatgaagcg tgtgcaggca gataataatc ctaatttctt
    10021 ttttttaact tacacaaaaa attttgaggt aaataacttt cttgtccttc cgaagcaatt
    10081 tgttacaccg aaatcgatta ttcaaagaaa accacttgca ccaactgcta gacgagcagg
    10141 ttggattggt tgtaacattg atttatcaca agtaccttct aaaggaagga tatttcttgt
    10201 gcaagatgga caagttagag atccagaaaa agttacaaaa gaatttaagc aaggtttatt
    10261 tttaaggaag agctctctgt catcaagagg ttggacaata gaaattctaa attgtataga
    10321 taagatagag ggttcagaat ttacccttga agatatgtat cgttttgaaa gtgacctaaa
    10381 aaatatcttt gttaagaaca atcatatcaa agaaaagatt aggcaacagc ttcaaatatt
    10441 aagagacaaa gaaataatag aatttaaagg tagaggaaag tatcggaaat tatgaaaacg
    10501 aaacaacttg ttgcatcaga agaggtgtat gatttcttaa aagtcatctg gcctgattat
    10561 gaaactgaaa gccgttacga taacctaagt ttaatcgtct gtaccttatc agatcccgat
    10621 tgtgtgagat ggttatctga aagtatgaaa tttggtgacg aaaaacaact agctttgatg
    10681 aaggaaaaat atgggtggga agtaggagat aaattgccag agtggctaca tagctcctat
    10741 catagattat tgttaatagg tgaattattg gaaagcaatc taaaactgaa aaagtataca
    10801 gtagaaatta cagaaacttt atcacgttta gtaagtatag aggctgaaaa tccagatgaa
    10861 gccgaacgac ttgtaagaga aaagtataag agttgtgaaa ttgttcttga tgcagatgat
    10921 tttcaggact atgatactag catatatgaa taggtagatg tttttatttt gtcacacaaa
    10981 aaagaggctc gcacctcttt ttcttatttc tttttatgat ttaatacggc attgaggaca
    11041 atagcgagta ggctggctac gacgattccg tttgagaaga acatttggaa ggctgtcggc
    11101 atgctgacaa agagattact gttgttgaga ccgacacctg cagcgattga aacagctgcg
    11161 ataaggaagt tgtgttcatt gttagcaaag tcaacacggg cgaggatttg catcccttga
    11221 attgatacaa aaccaaacat taccagcatg gcaccaccga ggacggagct tggaatgatt
    11281 tgggcaaggg cgccaaactt aggaagcagt ccaaggagaa ccaggaaacc agctgcgtag
    11341 tagattggca ggcgtttttt gatgcctgac aatttaacca aaccaacgtt ttgtgaaaat
    11401 ccggtgtaag ggaaggtgtt aaagattcct ccgagaagta cggccaaacc ttctgcgcgg
    11461 taaccgttgc gaaggcgcgt gctgtcgatt ggatcttttg tgatatcaga caaggctaga
    11521 taaacaccag ttgactcaac catagacacc gttgcgatga tacacatcat gacaatagat
    11581 gagatttcaa aggttggcat cccaaagtag agtggaattg ggacatggac aagtggagct
    11641 accgcaacag gagagaagtc caccaagccc atagtagcag caatggcagt tccaacaacc
    11701 agaccaatca aaatagagat agacttgata aatcctttgg taaagatgtt gatcaagagg
    11761 ataatcagaa cagtaatagc tgcaagcaag agactttgac cagttggctc tggaacgtta
    11821 tttcccatat ttccaatagc gacagggatc aaggttaaac caatcgtggt aataacagat
    11881 cctgttacga tagatgggaa gagattggct atttttgaga agatgcctga aacaagaacc
    11941 acgtaaatcc cagatgcgat aagggcacca aacatagcgc cactaccatg gctttgccca
    12001 atcataatca agggagcgac cgactggaat gcaactccaa gaacgactgg gagtccaatc
    12061 ccaaagtatt tgttgagttg gagttggagg aaggttgcca ccccacacat gaagatatct
    12121 gtagaaatca ggtaggtcaa ctgctcagct gaatagccaa gggctgtcgc aatcatgatg
    12181 ggaaccagga tagatcctga gtacatggct agtaagtgct gcaagcccag aacggctgct
    12241 tgcgagtgtt tttcttgagt ttgcattaga gatctgcctc cttaaatacg acctgaccat
    12301 tttcaaaacg atccaagcga gcaagtgata ggacagggta gcctgctttt tcaagcaaat
    12361 cacgaccatc ttggaaggat ttctcaatca cgataccgat agcttggact gtggcaccgg
    12421 cctgttcgat gatttgaatc aagcctttag cagcttggcc attagcaagg aaatcgtcga
    12481 taatcaaaac cttgtcctct ggtgagagga attttccagc gatagaaaca gtgctggtca
    12541 cctgcttggt aaaggagtag acttgagcag ttaagatgcc ttcgttcatg gtgatgttct
    12601 tagctttttt ggcgaaaatc atgggaacgt ttaaggcttc agctgtaaaa acggctgggg
    12661 caatacccga cgcttcaatg gttacgacct tggtaatgcc agtagcagca aatttttccg
    12721 caaaaacctt accaatctct cgcatcaagc taaagtcaac ttggtgggtt aaaaaggaat
    12781 ctaccttgag gatgttatca cccaagatat gcccatcctt gaggatgcgc tcttctaata
    12841 atttcataag acctcctaaa gtctaaaagc taatttactt gttgtttaaa tgtttctata
    12901 gtgatccctt ttgctaatac tatatatttg ataaaactat tacgagcgaa gcgagtctta
    12961 tcaaatattt cccgttgtag tggtatcata gacaatgatc ttgttattgt ctatgacggg
    13021 atttttgaga gtaaaatagt tcggggaact attttagcct aagcctagaa atgaaagagc
    13081 taggggctca aaaattaggg atgaaattcc ctggattcct gaaattattc acaggataat
    13141 ttcacctctc gtccgcacta attaagggaa atattaaaaa tattcaaaaa agacctactt
    13201 aatctctaag taagtcccct aaatagacat ggcaaaaacg gccatatctc actgctgact
    13261 tacttattgt taggcgttcc ggcaccttgt agaaacgtcg tgccaattca cgacataaac
    13321 aagtaaaacg atattcaatt ttaaataggc ttgagccaat gtttttattt tacactaaat
    13381 aactttagaa atcaactatt ttgttagtgt tttggtttaa aaaacgaaca aacagaagag
    13441 agggtgaaca aaaactccat tgtaagctaa catttatact aaatgaaaat caaagagcaa
    13501 actaggaagc tatccacaac ctcaaaacac tgttttgagg ttgtggatag aattgacaga
    13561 gtcagtatca tatacctacg gtaaggcgac gttgacgtgg cttgaagaga ttttcgaaga
    13621 gtattagaag atttttccat cataaaaggc atactatcaa gtttttagac acctgacaat
    13681 atgccttttt ctaactttaa agacttttcc caatttttat tattctactc gctaaatctt
    13741 aaaaaatagc catctggatc caaaactgca aatttatgag gatagatata gggatcactg
    13801 acacgaaact ttcttttggt caagggacga taaataggat agtttgcctc catcactttt
    13861 tgatagagtt ttggaacatc ctttatgcca aaggagagat tgactccacg accaaagggg
    13921 taggtcagtt cagctagttg atcctttgtt ccctcctcta acattagttg acactcttca
    13981 agagaaagag aaagttttct tctggacgtt ggtattcaat cctaaaaccc agtaaaccac
    14041 agtagaagga ccgggactgt tcgatattcg atacaagaaa ctcgggaatg accgcattgt
    14101 agtccatata gaaaatcctt acaagtcaat ttccaagaca atcggtgtat ggtcttggcg
    14161 agcacctgag tcaatcatat cagatttagt gaccttgtca gcgatacggt tacttgtgag
    14221 ccagtagtcg attctccagc ctgtattgtt gattttagaa gttttgctgc gttgtgccca
    14281 ccaagtgtag cgttcaggaa catcgccatg aacatggcgg aaggtatcag taaatccagt
    14341 tgccaatagg ttggtaaatc cagcacgttc ctcgtcagta aatccaggtg aacggcggtt
    14401 gctagcagga tttgcaaggt cgatttcatt gtgggctacg ttgtagtcac cggtcgcaag
    14461 gactggtttt tctttgtcta gttcagccaa atactccgca tatttgacat cccagacttg
    14521 gcgttcttcc aagcgtttaa gaccatcgcc agcatttggt gtgtaaactt gggtcacgaa
    14581 aaatgcatca aattctagag tgatgatgcg gccttccaag tccatggtag aaggggcacc
    14641 gatttctggg aagctgatcg taggcgtaag ttctttctta taaaggaaca tggttccagc
    14701 atagccttta cgggcaggct cttgggaaga gcgccacgtg ttttcgtagc ctgggaagag
    14761 ttcttctaaa atttccacgt gtttctttgt aggtcctttg gcagaaagct tggtttcttg
    14821 gatagcaata atatcagcat tttcagcgac caaggtttgt aggacttctt gggacaattt
    14881 ggcacgagct gagtcactag ttagggcagc gtttagggaa tcaatattcc atgagataag
    14941 tttcataaag ttaccttttt cattcagatt atagatttta ttataccaaa aaaaggtcta
    15001 tttccccaac gtatggtttg aaaaattact ctctttcgtt tataattaag aatgatttta
    15061 tgaaagggag tgaaaataca tgaaattcta ctcttatgac tatgtactca gccaaatcgg
    15121 tcagcaaaat ggtatcatgg ttggctttgg gattgtttta ttagctgtga cagttttttt
    15181 gctttcaagg cataccatga taaaaaagga atcaaatttc gtgagttggt catgatttca
    15241 gctctggcct tatttagcta tgcttttggt cagcatcacg acttatcaaa acaatcaagt
    15301 ttctaacaat aaatttcaaa cttcacttca tttcatcgag gttgtttcca aagatttggg
    15361 agtagacaag tcagaagtct atgttaatac ttccacaaac acagatggcg cacttatcaa
    15421 ggtgggagat cgctattatc gtgccctaaa cggaagtgag ccagacaagt acctgttaga
    15481 gaaagtcgaa ttgtataaga cagacgcaat tgaactggtg gatgtgaaca aatgacactt
    15541 aattatatcg aaattttaat caaactgatc ttgactctca aatagctcaa caacaatgtt
    15601 cactttgtga aacgtttgat tgatggtaag ccaactctcc ttatcaaaaa tgggaatatt
    15661 gacccataag cctgtcgttc agttggtttg tctgcatcgg atgtagccct caaacttcgt
    15721 agccaaggga ttttccagat gaagcaagtc aaacgagctg tgcaagagca aaatgggcaa
    15781 ctcatcgttg tgcaaatggg agatgaaaat cctaagtatc cagttgtgac tgacggtgtg
    15841 attcaagtag acgtcttgga atcgattggt cgtagcgaag agtggttgct tgataacctc
    15901 agcaaacaag ggcatgacaa tgtagccaat atctttattg ctgaatatga caagggtgct
    15961 gttacagtcg taacttatga ataagaaaaa cctggggtct tgtactcttc gaaaatctct
    16021 tcaaaccgcg tcaacgtcgc cttgccgtat gtaggttact gacttcgtca gttctatcta
    16081 caacctcaaa gcagtgcttt gagcagcctg cggctagttt cctagtttgc tctttgattt
    16141 tcattgagta ttggcctcag gtttccattt gcaatcagaa agggatttta tgtccattat
    16201 tcaaaaactt tggtggtttt tcaagttaga aaaacgccgt tatctagtcg gaattgtggc
    16261 cctgatcttg gtttccgtcc tcaatctcat tcctcctatg gttatggggc gagtcattga
    16321 tgccatcaca tcggggcaat taacccagca ggacctcctt cttagcctat tttacttgct
    16381 acttgcagcc tttggtatgt actatttgcg ctatgtgtgg cgtatgtata tccttgggac
    16441 ctcttattgc ttgggacaga tcatgcggtc tcgcttgttt aagcatttca caaaaatgtc
    16501 gccagccttt tatcaaacct atcggacggg tgatctgatg gcacacgcaa ccaatgatat
    16561 caatgccttg actcgtttag caggtggcgg tgtcatgtct gcggtggatg cctctatcac
    16621 ggctctggtg actttgttga ccatgctctt tagcatctca tggcagatga ctcttgttgc
    16681 cattctcccc ctacctttca tggcctatac gactagtcgc ctagggagaa agactcataa
    16741 ggcctttggc gaatcccaag ctgctttttc tgaactcaat aacaaggtac aggagtccgt
    16801 atcaggtatc aaagtgacca agtctttcgg ttatcaggca gacgagttga agtcttttca
    16861 ggcagtcaat gaattaacct tccaaaagaa cctgcaaacc atgaaatatg atagtctctt
    16921 tgaccctatg gttctcttgt ttgttggttc gtcctatgtt ttaacgcttt tggttggctc
    16981 cttgatggtt caggaagggc agattacagt tgggaatcta gtcaccttta tcagctattt
    17041 ggatatgctg gtctggcctc ttctggccat cggtttcctc tttaatacta ctcagcgagg
    17101 gaaggtttct taccagcgga ttgaaaatct tttgtctcag gaatctcctg tacaagaccc
    17161 tgagcttcct ctggatggta ttgaaaatgg gcgtttggag tatgccattg acagctttgc
    17221 ttttgaaaat gaggaaacac tgacggatat tcactttagt ttggcaaaag ggcaaacact
    17281 gggcttggtt gggcagacag gctctgggaa aacgtcctta atcaagctcc tcttgcgtga
    17341 atacgatgtg gataagggta ctatttatct aaacggtcac gatattcggg actatcgtct
    17401 gacagacctt cgcagtctca tgggctatgt tcctcaggac cagtttctct ttgcgacttc
    17461 aatcctagac aatatccgct ttggcaatcc taacttgtcc ctttcagcgg tcgtggaagc
    17521 tactaagcta gcccgagttt accaagatat tgtagacatg cctcaaggat ttgatacgct
    17581 gattggtgaa aaaggagtca gtctttccgg tggtcaaaag caacggttgg ctatgagtcg
    17641 ggctatgatt ttagaacctg atatcttgat tttggatgat tccttatccg ccgtagatgc
    17701 caagacagag tatgcgatta tcgacaacct caaggagacg cgaaaggaca aaacaaccat
    17761 tatcactgcc catcgcctga gtgcagttgt ccatgcagat ttgattttag tcctgcaaaa
    17821 tggtcaaatt atcgaacgag gcaggcacga agacttgcta gctttggatg gctggtatgc
    17881 ccaaacctac cagtctcagc agttggaaat gaaaggagaa gaagatgcag aataaacaag
    17941 aacaatgggc tgtattgaag cgcttgatgt cttatctcaa gccctatgga ctcctgacct
    18001 ttttggcact cagttttctc ctagcgacga cggtcattaa aagtgtcata cccctcgtgg
    18061 cttcccactt tatcgaccag tatctcagca atcttaacca actagccgtt accgttttgc
    18121 tggtctacta tggtctctac atcctacaaa ctgtagttca gtatgtaggc aatcttctct
    18181 ttgcgcgcgt gtcttacagt attgttaggg atattcgtcg agatgccttt gccaatatgg
    18241 agaaactggg catgtcttac tttgacaaga cgccagcagg ttctatcgtt tctcgtttga
    18301 ccaacgatac cgagacgatt agtgatatgt tttctgggat tttatctagc tttatctcag
    18361 cagttttcat ctttctgaca accctttata ccatgttggt attggatttt cgtttgacag
    18421 cattagtctt gctctttctc cccttgattt tccttttggt caatctctat cggaaaaaat
    18481 cagtgaaaat cattgagaaa accagaagtc tcttgtcaga tatcaatagt aagctggcag
    18541 agaatatcga gggaatcagg attattcagg cttttaatca agagaagcgc ctgcaggcag
    18601 aatttgatga aatcaaccaa gaacacttgg tctacgccaa ccgttctgta gccttggatg
    18661 ccctcttttt gagacctgcc atgagtttgc tgaaacttct aggctatgca gtcttgatgg
    18721 cctactttgg ctaccgtggt ttttctatcg ggataacggt cgggaccatg tatgccttta
    18781 tccagtacat caaccgcctt tttgacccct tgattgaggt gacgcaaaac ttttcaactc
    18841 tgcaaacggc tatggtttct gcaggtcgtg tctttgccct gatagacgag aggacctatg
    18901 aacctcttca agaaaatggg caagccaaag tccaagaagg caatatccgt tttgaacatg
    18961 tgtgtttctc atatgacggt aaacatccga ttctggatga catttctttc tctgttaata
    19021 agggtgaaac cattgccttt gtaggtcata caggttcagg gaaatcgtct attatcaatg
    19081 tcctcatgcg cttttatgaa ttccagtcag ggagagttct cttggatgat gtggatatca
    19141 gggatttcag tcaagaagag ctgagaaaaa acatcggttt ggtcttgcag gaacccttcc
    19201 tctatcatgg aactattaag tccaatatcg ccatgtacca aaaaatcagt gatgatcagg
    19261 ttcaggctgc ggcagccttt gtggatgcag attcctttat tcaagaactt cctcaggggt
    19321 acgactcccc tgtttccgag cgtggttcga gcttctctac tgggcagcgc cagcttcttg
    19381 cctttgctag aacagtcgcc agccagccta aaatcctgat tttggatgaa gcgacagcca
    19441 atattgactc tgaaacagaa agcttggttc aagcttctct ggcgaagatg agacagggcc
    19501 gaacaactat tgctatcgct caccgccttt ctactattca agacgccaac tgcatctatg
    19561 tcttggataa gggacgcatt atcgagagtg gaacccatga ggaactcttg actctgggag
    19621 gaacctatca caagatgtat agtttgcagg caggggccat ggccgatact ctttgaaaat
    19681 ctctttaaac catgtcagct ttatctgcaa tctcaaagct gtactttgat tttcattgag
    19741 tactagaagg aaatccttca aattacagat ttctttcacc gccttttcca ttttgtggta
    19801 taatgaaaaa tgttgacaaa tagtataata aaaacaaagg agaacagtat gctgaaatgg
    19861 gaagacttgc ctgtggaaat gaaatcaagc gaggttgagt cttactacca tcttgtctct
    19921 aaaaggaagg gttcgctgat tttcaagcgt tgcttggact ggtttttggc cttggtctta
    19981 ctggttctaa cctctcccat ctttctcatc ttgagcattt ggatcaagtt ggatagcaag
    20041 gggccagtga tttacaagca agagcgtgtg acccagtaca accgtcggtt caagatttgg
    20101 aagttccgta ccatggtgac ggatgcggat aaaaaaggaa gtctggtgac ttctgctaac
    20161 gatagccgta ttaccaaggt tggaaatttc atccgacgtg tccgtttgga cgaactgcct
    20221 cagttggtca atgtccttaa aggtgagatg tcctttgtcg gtacacgacc tgaagtgcca
    20281 cgttatacag agcagtatag ccctgaaatg atggcaacct tgctcttgca agcaggaatt
    20341 acctctccag ccagcatcaa ctacaaggat gaggacacca tcatcagtca aatgacggag
    20401 aaaggtctgt cagttgatca ggcctatgtg gagcatgttc ttcctgaaaa gatgcgctat
    20461 aacctcgcct atctccgaga gtttagtttc tttggggaca tcaaaatcat gtttcaaacc
    20521 gtgtttgagg tactaaaata aagtagtcat aagaaaatga gtacagataa aaggagcaaa
    20581 tcaatgccaa attacaatat tccattttca ccgcctgata tcacagaagc agaaattgct
    20641 gaagtagcgg ataccctgcg ttctggttgg atcacaacag gtcctaaaac aaaagaactg
    20701 gagcgccgct tgtctcttta cacacagaca cctaagactg tttgtctcaa ctctgcgaca
    20761 gccgctctgg agttgatttt acgcgttttg gaagtgggac ctggtgatga agtcatcgtt
    20821 ccagccatga cctatacagc ttcatgtagt gtcattacgc acgtgggagc aacccctgtc
    20881 atggtggata tccaagcaga tacctttgag atggactatg acctgcttga gcaagctatc
    20941 actgagaaaa ctaaggtgat tatcccagta gagctcgcag ggattgtttg cgattatgac
    21001 cgtttgttcc aagtcgtgga gaaaaaacgt gacttcttta ctgcttcaag caagtggcaa
    21061 aaggccttta accgtattgt cattgtctct gatagtgccc acgctttggg atctacttat
    21121 aaaggacaac cttctggttc tatcgctgac tttacttcct tctcattcca tgccgttaag
    21181 aactttacaa cggcagaagg tggaagtgcg acttggaaag ccaatccagt gattgatgac
    21241 gaagagatgt acaaggaatt ccaaatcctt tcccttcacg ggcaaactaa ggatgctctt
    21301 gccaagatgc aattggggtc atgggaatac gatatcgtta caccagccta taagtgcaac
    21361 atgaccgata tcatggcttc acttggtttg gtacaattgg accgctatcc aagtttgttg
    21421 caacgccgta aggacattgt gaaccgctat gatagtggtt ttgcaggttc tcgcatccat
    21481 cctttggcac acaagactga aactgtcgaa tcttcacgcc acctctacat cacccgtgta
    21541 gaaggagcaa gcctagaaga acgcaacctc atcatccaag aattggctaa agcaggaatt
    21601 gcaagtaatg ttcactacaa accgcttcct ctcttgacag cctataagaa tcttggattt
    21661 gatatgacga actatcctaa ggcctatgcc ttctttgaga atgaaattac cctccctctt
    21721 catactaaat taagcgatga agaagtagac tatatcattg agactttcaa aacagtttct
    21781 gaaaaagtgc taactttatc aaaaaaatga caaactacag tcaagcgaaa gtgatcctgt
    21841 ccctaaaaag tctaattgag tgtaaaaact gttgttttca attgataata gtttacacct
    21901 gtagttgagg ctcctttctc ctcagagaga gaatttttat aggattttcc tttcttgtgg
    21961 gagtcccgtg gtttgaaata agatgtgagc aatttggtgt agcatttaga atccttacta
    22021 gacatcattt agaaaatcta gtgtcttgtt ctagttttca attcacccta ttttttgaaa
    22081 gacgtgagtt tccatgagtg agattgtgga aactcgcgtc ttttttttgt tttcagaata
    22141 ttgttcaaag ttttgtgcct gtctttcatg ttctagtcat tcttttgcat gatagaattt
    22201 ataacatgtt gatattataa taatgcaaat attctatatg tttagtgatg cttgctatac
    22261 atcattagat ctcctgcgag acaatctata aaacacttgt ctacgattac ctatatgccc
    22321 tattccagta ttttagaagc actgcatcta tttttatcga ggttaaatct agcttttata
    22381 gaaggtctat ttaagaaata tattgtagtg ttttagtttc aatccgccat atgagcgata
    22441 ttcaggtaaa tatccctggc gaatgcttgt atgacaagat atttgttctt tcatttataa
    22501 tttacaacat atcaacaaat ttaaatatag taaatgggat attttatatt caagctaaga
    22561 aagatagcat cacttttgaa tggaaggcta aagagcaaac taggaagttg gccatagata
    22621 gctcaaaacc ctgctttgag gttgtagata taataaaatg aaataagaat aggacaaatc
    22681 gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattatag
    22741 tttcagtcta ctatagaact gaccaagtca gtaacctaga cttagggcaa ggcggcactg
    22801 acctagtttg aagagatttc cgaagagtat aaattttaat attttcttgt gttattcctt
    22861 gacaattcaa tttggaaaat atatgataaa gataatgaca gcggtgtcat tctatctatt
    22921 ttaagaaaag taataatcaa ttgttaaaaa tagtaaaaaa attggaggtt ctgatgaaat
    22981 attttgttcc taatgaggta ttcagtattc gtaaattaaa ggtggggact tgctcggtac
    23041 tattggcaat ttcaattttg ggaagccaag gtattttatc ggatgaagtt gttactagtt
    23101 cttcaccgat ggctacaaaa gagtcttcta atgcaattac taatgattta gataattcac
    23161 caactgttaa tcaaaatcgt tctgctgaaa tgattgcctc taattcaacc actaatggtt
    23221 tagataattc gttaagtgtt aatagtatca gctctaatgg tactattcgt tccaattcac
    23281 aattagacaa cagaacagtt gaatctacag taatatctac taatgaaaat aagagttata
    23341 aggaagatgt tataagtgac agaattatca aaaaagaatt tgaagatact gctttaagtg
    23401 taaaagatta tggtgcggta ggtgatggga ttcatgatga tcgacaagca attcaagatg
    23461 caatagatgc tgcagctcaa gggctaggtg gaggaaatgt atattttcct gaaggaactt
    23521 atttagtaaa agaaattgtt tttttaaaaa gtcatacaca cttagaattg aatgagaaag
    23581 ctacaattct aaatggtata aatattaaga atcacccttc cattgttttt atgacaggtt
    23641 tatttacgga tgatggtgcg caagtagaat ggggcccaac agaagatatt agttattctg
    23701 gtggtacgat tgatatgaac ggtgctttga atgaagaagg aactaaagca aaaaatctac
    23761 cacttataaa ttcttcaggt gcatttgcta ttgggaattc aaataacgta actataaaaa
    23821 atgtaacatt caaggatagt tatcaagggc atgctattca aattgcaggt tcgaaaaatg
    23881 tattagttga taattctcgt tttcttgggc aagccttacc caaaacgatg aaggatgggc
    23941 aaatcataag taaggagagc attcagattg aaccattaac tagaaaaggt tttccttatg
    24001 ccttgaatga tgatgggaaa aaatctgaaa atgtgactat tcaaaattcc tattttggca
    24061 aaagtgataa atctggggaa ttagtaacag caattggcac acactatcaa acattgtcga
    24121 cacagaaccc ctctaatatt aaaattttaa ataatcattt tgataacatg atgtatgcag
    24181 gtgtacgttt tacaggattc actgatgtat taatcaaagg aaatcgcttt gataagaaag
    24241 ttaaaggaga gagtgtacat tatcgagaaa acggagcagc tttagtaaat gcttatagct
    24301 ataaaaacac taaagaccta ttagatttaa ataaacaggt ggttatcgcc gaaaatatat
    24361 ttaatattgc cgatcctaaa acaaaagcga tacgagttgc aaaagatagt gcagaatatt
    24421 taggaaaagt atcagatatt actgtaacaa aaaatgtaat taataataat tctaaggaaa
    24481 cagaacaacc aaatattgaa ttattacgag ttagtgataa tttagtagtc tcagagaata
    24541 gtatattcgg tggtaaagaa ggaattatta ttgaggattc aaagggtaaa ataaccgttt
    24601 taaataacca attttataat ttatccggta agtatatatc attcatcaaa tctaatgcaa
    24661 atgggaaaga acctgttata cgtgatagcg atggtaattt caatattgta acggagaatg
    24721 ggctttacaa aattgtaaca aataatttaa gtgataaaaa cgaaaaagaa aaaaacaaag
    24781 aggaaaaaca atctaattca aataatgtaa ttgatagtaa ccagaagaac ggagagttta
    24841 actcaagtaa agataataga caaatgaatg acaagatcga caataaacaa gataataaga
    24901 cagaagaagt aaactataaa atagttggag atggcagaga aactgaaaat catattaata
    24961 aatctaaaga aatagtagat gtaaaacaaa aattaccaaa gactggttcg aacaagatta
    25021 tggaactatt cttaacagtg acaggaattg gtttactttt gacactaaaa gggttgaagt
    25081 attatggtaa agataaataa aatttgttcg atacaaggaa gttccgtaga aaatgaggat
    25141 attgtaggtt cacaaaatca gtatttttgg attattggtg gagctacaga tttatataat
    25201 tctaaagagg agataggtta ttcagtctca gaagttgtac atattttatc agaaagtttg
    25261 tcggttaatt gtaaagaatc aaaaactctt aaacaaatat ttgaaactgc tttactcgag
    25321 gttaaagatg aaatcggttt aaactcatat gaattaacag agtatagtaa aatgaaataa
    25381 taataggaca aatcaatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag
    25441 gtgtactatt ctagtttcaa tatactatat tatcgcttac caatatttgc ttttatattt
    25501 gctaaacttt cagaaaaaaa gttggagtat atgatgctag gtgactgcgt catgttagta
    25561 aacgaaatgg aaataactga tcatagagta gataacttat ttgaaaaagg gaaaaatgag
    25621 ataaaagatt caattggtac aaatagtgtt ttaaataaaa aaattatttt acaaaaaatc
    25681 agaaaattat ctaatcaacc gagtgggtac tggataggtt cgttggatga gagattttta
    25741 gaccatgcta ttattaatca aatagatgtt actagtgaac aaattgtttt aatgagcgat
    25801 ggcttttatg aattctatca aaataatcaa aataaaactt ttgaagagtt aattaagatg
    25861 agatttaatt cttctgctat tgatccaatc tatggaaaga aggatgatgc aagtattcta
    25921 gtcattgatg tttgatatat tgtttaaaat attaattgtt actattgaac tttgttaaga
    25981 agaggtacct aaatgctaag gttatattta gaaaatgaaa ttatagaatt atcaaataat
    26041 ttagagacca tttgggtatc tgtgcttgat aaatatgaga agttatttga atatttatca
    26101 aatgaagaac gaatagaatt gattaaagaa gatttaatca taaatgagtc agttctaaat
    26161 attgataaaa aaggatatga gttaatttgt ttacaacatc ctgtttcata tgacttaaga
    26221 agaattatta gtgtaataaa aatatcaact gacattgaac gtattgggga tagaattgtt
    26281 gaaattttaa aaaatctaca gattcttcaa aataatgaaa ttttgaagaa aattatttca
    26341 gaaataaaaa tacttcatga agttatcgaa ctgcatatga atagggctat atcttgttat
    26401 agagaggaac aatctggatg tttagatatg gttgttatac aaaaacagaa tgagatagaa
    26461 gagcttagta taaatatgga aaagaaaata atgaattaca tatttgaaga tgatgggaac
    26521 gtttctgaag taattagtgc tttagatatt attcatcacc ttgataaaat tgctcatact
    26581 acgcaagcaa tttataaatg gataatgtat agaaaatatg ggaacataaa ttagaaagaa
    26641 aaatatatga aaacaattat tgataatttt gttgatagag taattgaata cggaatgtat
    26701 aatgaaattg acaaaatata tgtgaaaaat agagtactag cgttaatagg tgaggaggga
    26761 attgatcgca tttccgatga aaatgacctg aaacaaataa aagattactt agtggaaatc
    26821 gccttaaaaa acgataaaat taaagattta atcgaggaaa aggaatgttt aggagcagag
    26881 ttaatgaatt tcatagttcc tttacctagt cgattaaatg atattttttg gagttcatat
    26941 gatatatcac ctcaagaagc agttgaagag ttttataagt taagtaaaga tagtgattat
    27001 attaaaactt ctgctattgc taagaatatt gagtttcgag catcaactaa atacggagag
    27061 ctagagatta cgataaattt gtcaaaaccc gaaaaagatc caaaaacaat tgctgctgaa
    27121 aaattagtaa aagcaactaa ttatcccaaa tgtttactat gtatggaaaa tgaaggatat
    27181 caggggcgaa taaattatcc agcacgttcg aatcatagaa ttattcggtt gaaacttggt
    27241 gacgaagtat ggggattcca gtattctccc tactcgtact ttaatgagca tgcgatattt
    27301 ttgaatagtc aacatgtacc aatggctatt acctctaaaa catttgaaca attattggag
    27361 attgttgata ttttgccagg atattttgct ggttcaaatt ctgatcttcc tatatcagga
    27421 ggctccattc ttagtcataa ccactaccag ggagggaaac atattttccc aatggaaaaa
    27481 gcaaaatttg agagtgaatt ttgttttaaa gactttgagg atgttaatgc tggtattgta
    27541 aaatggccaa tgtcagtaat taggttacaa agtgaaaata aaaatcgctt gttagattta
    27601 gctactaaaa ttctaaataa gtggagagaa tattcagatt tagaagtaga catcattgct
    27661 atgactgaag atgtcccaca ccatacggtg actcctattg ctcgtaaagt ggacgggaga
    27721 tacgaattag atattgttct aagagataat catactactg aacaataccc agatggtgtt
    27781 ttccatcctc atcaagatgt acaacatatt aaaaaggaaa atatcgggtt aatcgaagtg
    27841 atgggacttg cgatattacc acctcgtttg aaaccagagt tagaagaagt tggaaaatat
    27901 cttttaggag aggataatgc aattgcggat tatcatttag aatgggccga ccaattgaaa
    27961 gaaaaatatc ctcgcattaa taaagaagag gttaatagcg tagttcaaca cgaagcagga
    28021 caagtgtttg cgagagttct ggaagatgca ggagtttata agaatacacc gtctgggcat
    28081 gaagcgttta tgagatttgt taagtcggtt ggaattaatt aggaggaaac ccagatggca
    28141 atattggtaa caggcggagc tggttatatt ggtagccata ccgtagtaga attactaaat
    28201 ttaggaaagg aagttatcat tgtcgacaac ctttcgaact ctagcaaatt ggtgctagac
    28261 cgtattgaag caattacagg aatacgtccc gtgttttacg aattagatgt ttgtgataaa
    28321 caagcattga gaaaggtatt tgaacaagaa tcgattgatg ctgcaattca ttttgcaggt
    28381 tataaagctg tcggagaatc cgtgcaaaag cctgtgatgt actacaaaaa taatattatg
    28441 agtacattgg cacttgttga agtgatgtca gaatttaatg ttaaaaagat tgtcttttct
    28501 tcaagtgcga ctgtatatgg aattaacaat cagtcacctc taattgagac gatgcaaaca
    28561 agtgcgacaa atccttatgg gtatacgaaa gtgatgcttg agcaaatttt aaaagatgtt
    28621 catgtggcag attcagaatg gagtattgcg ttgcttcgtt atttcaatcc aattggtgct
    28681 catgagtctg gtttgattgg ggaagatccc tcaggaattc ctaacaactt gatgccttat
    28741 attgcacaag tagcggtagg taagctatca gagctaagtg tgttcggaaa tgattatgat
    28801 acgcttgatg gtactggtgt gcgtgattat atccatgtag tagatttagc aataggacat
    28861 ataaaagctt tagaaaaagt atctgaaaaa acagatgttt atatctataa cctaggctcg
    28921 ggagaaggca ctagtgtatt acaacttgta aatacatttg aaagtgttaa taagatccct
    28981 attccttata aaatagttcc aagacgttca ggagacgttg caacttgtta tgcaaatgca
    29041 gacaaagcat ataaggaatt aaattggagg acaacaaaat cgattgaaga catgtgtaga
    29101 gatacatgga attagcaatc aaaaaatccc aatggctata attgatgata ctgtctatat
    29161 gagtgctgta ttttggaaaa attacttaac cttttaatga aatgcatatt taatgaaaga
    29221 taaattaaaa aaaaatgttt gacagcgctt gacaaaggaa acggtttcat tgtataatgt
    29281 aaacatgatg acaccgatgt caaatataaa aaagaaggtc tttatatgaa aaacttaaca
    29341 aaaattaagt tcaaagagaa tggggaattt aatcatttcc ctgggaatac agttgtagca
    29401 aatctttata ctaaacaaga tttgatggaa gttgttgata ttattcaatc acgttataga
    29461 gaattaccat ttatcgataa gtttacttta actccaagga attctattca catgactgta
    29521 attgaattgt tgtgccatga aaatcgtgaa acggagtttt ggagcagtaa tcttcctcta
    29581 gatacacctt tacaggaaat acatgattac tttgctaaac aacttgaaat ttttccattg
    29641 ttggatgaag aaattcatat gcgtataact gaaatgggaa aacaaaacat actagttgaa
    29701 cctgcagatg aagtttctgc aaagagatta gaagaaattc gtacttatgt ctcagaaaaa
    29761 gcaggtgttt gtttccctaa tcatgataga tatcaattcc atatttcaat tgggtatctt
    29821 cggattcctc taaccgaaga ggaggaagaa gagtttacta aagtcagagc agaattaact
    29881 gaaattttat tagagaagat tccaactatt actgtaaacc gtattgacta tactgtattt
    29941 gaagatatga gacaatttgt tccatatcac gaaaaattta aataaaataa taaaaaagga
    30001 gaacttatca tgaaaaaaat gaaagtttgg tctactgtac ttgcaacggg agttgctctt
    30061 actacacttg ctgcttgctc tggaggttca aattctacga ctgcttcttc atctgaagaa
    30121 aaagctgata aaagtcaaga attagttatc tattcgaact cagtctcaaa tggtcgtggt
    30181 gattggttaa ctgctaaagc aaaagaagct ggttttaata taaaaatggt tgatatcgct
    30241 ggcgctcaat tagcagaccg tgttattgct gagaagaata atgcagttgc agatatggta
    30301 tttggaattg gtgctgttga ctcaaataaa attagagatc aaaaattact agtacagtac
    30361 aagcctaaat ggttagataa aattgatcaa tctttatcag ataaagataa ttattataat
    30421 cctgtgattg ttcaaccatt agttttaatt ggggcgcctg atgtaaaaga aatgcctaaa
    30481 gattggactg aattaggtag taagtataaa ggtaaatatt caatttatgg tcttcaaggt
    30541 ggtacaggac gggcaattct agcaagtatc ttagttcgtt accttgatga aaaaggagat
    30601 ttaggcgtat cagaaaaagg atgggaagtt gcaaaagaat actttgcaaa tgcctatact
    30661 cttcaaaaag gtgaaagctc agttgttaaa gcgttagata aagaaagccc aattcaatac
    30721 ggtatgatct ggggttctgg agcgttaatt ggacaaaaag aacaaaatgt tgaattcaaa
    30781 gttatgactc ctgagattgg tgtaccattt gtaactgaac aaactatggt tttaagcact
    30841 agtaaaaaac aagcgttagc taaagaattt attgattggt ttggtcaatc agaaattcaa
    30901 gtagaatata gtaaaaaatt tggatctatt cctgcaaata aagatgccct aaaagagtta
    30961 cctgaagata cgaaaaaatt tgttgatcaa gtgaaaccac aaaatattga ctgggaagct
    31021 gttggaaagc atttggatga atgggtagaa aaagctgaat tagaatacgt aaaataagaa
    31081 ataagagtta ttttttatgt ccaagtctct ctattatttc taaatttaag gaagaaataa
    31141 agagaggctt ttggttttag taatagaggg agttagtgag atgattaaat ttgataatat
    31201 tcaaattaaa tatggtgatt ttgttgcaat tgataatctg aatttagata tacatgaagg
    31261 ggaattcttt acatttcttg ggccttcagg atgtggtaaa tcaactactt tgagagcatt
    31321 ggtaggtttt ttagatccat catcaggaag tattgaagtt aatggaacag atgtcactca
    31381 tttggaacct gaaaagcgtg gaattggtat tgtatttcaa tcttatgcgc tatttccaac
    31441 tatgactgtt tttgataata ttgcatttgg tttaaaagtt aagaaggtag ctccagatgt
    31501 tattaaagct aaagtatcag cagtggcagc aaaaattaag atctctgatc aacagttaca
    31561 gcgtaatgta tcagaattat ctgggggtca acaacaaagg gtagcattgg ctcgtgctct
    31621 ggttcttgaa cctaaaattc tttgtctaga tgaaccattg tcaaaccttg acgcaaaatt
    31681 acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa gagttaggta ttactacttt
    31741 atatgttact catgatcaag aggaagcctt gactttatct gatagaattg cagtctttaa
    31801 caatggatac atcgaacagg tcggtacacc agtagagatt tatcataatt ctcaaactga
    31861 atttgtatgt gattttattg gagatattaa tgttttgacc gatgaaacag tccacgaagt
    31921 attattgaaa aatacaagcg ttttcttaga ggataaaaaa ggatacattc gattagagaa
    31981 agttcgattc aatcgtgaaa ctgaacaaga ttttattcta aaagggacaa ttattgatgt
    32041 tgagttttct ggagttacaa ttcactatac aataaaagtt tctgaaagtc agattcttaa
    32101 tgtaacaagt attgatagtc aggctgctat tagatctgtc ggagaaagtg tggaattatt
    32161 tatcacacca tcagacgttc tgcaatttta aggaggtgca gtatgcgtca taaattaaat
    32221 ttaaaagatt ggcttattcg tttagggtta atctggttct tagtaacatt tattatttat
    32281 ccaaactttg atctagtagt gaatgtattt gtaaaaggag gagaattttc ccttgatgct
    32341 gtacatcgtg ttctaaaatc tcagagggca cttcagagta ttatgaacag ttttaagtta
    32401 gcattttcac ttattattac agttaatgtc gtaggtattc tttgtgttct atttacagag
    32461 tactttgata ttaaaggtgc taaaatttta aaattaggtt atatgacctc tttaatttat
    32521 ggaggagtgg ttttagcgac tggatataaa tttgtctatg gtccttatgg attgattaca
    32581 aaatttttac aaaatgttat cccttcttta gactctaact ggtttattgg gtatggtgca
    32641 gtcttattca ttatgacatt ttcaggaact gctaatcata cattgttttt aacaaataca
    32701 attcgaagcg ttgactatca cactattgag gctgctcgaa atatgggagc aaaaccattt
    32761 actgttttcc gaaaagtagt gttaccaacc ttaattccaa ctctatttgc acttactatt
    32821 atggtttttc ttagtggttt atctgcagta gcagcaccca tgattgttgg tggtaaagaa
    32881 tttcaaacta taaatccaat gattattaca tttgcaggga tggggaattc tcgtgattta
    32941 gctgccttac ttgcaattat tttaggtatt gcaactacaa ttttgcttac tatcatgaat
    33001 aagatagaaa aaggtggaaa ttatatttct atctctaaga ctaaagcgcc tcttaaaaaa
    33061 caaaaaattg cgtctaagcc ttggaatatc attgctcaca ttgtagcata tggattgttc
    33121 acagttttca tgcttccact aatttttata gtattatact catttacaga tccagttgca
    33181 attcaaacag gtaacttaac attatcaaac tttactttag aaaattatcg cttattcttt
    33241 agtaatagtg cggcattctc tccattcttg gtcagcttta tttattctat tattgctgcg
    33301 acaacagcaa caattctcgc agttgtattt gctcgtgttg tcagaaaaca taaatctcgt
    33361 tttgatttct tatttgaata tggtgctcta cttccttggt tactaccaag tacactttta
    33421 gcagtaagtt tattatttac ttttaatcag ccacaatttc ttgtcttgaa tcagattttg
    33481 gtaggtagtt tggtaattct acttattgca tatatagttg taaaaatccc attttcttat
    33541 agaatggtac gtgctatttt atttagtgtt gatgatgaga tggaagatgc agcaagaagt
    33601 atgggtgctt caccttttta tactatgatg aaggttatca ttccatttat tttaccggtt
    33661 gttctctctg ttattgcttt aaactttaac tctttattaa ctgacttcga cttatctgta
    33721 ttcctttacc atcccctagc tcaaccatta ggtattacga ttcgatctgc aggtgatgaa
    33781 acagcaacat ctaatgcaca agctctggta tttgtttata caattgttct gatgattatt
    33841 tctggaacgg tattatactt cacacaaaga ccggggcgta aagtaaggaa ataatcatga
    33901 cagccactag tcttgggtta tcaaatattg aaatagttgt caggattgtt ttatcagtag
    33961 tcattggtag tataattggt ttagagagag ggagcaaatc ccagcctgca ggcatccgaa
    34021 cttatagtat tgtttgtcta gctgcatgtt tgattatgat gacgaatgaa tacgtatctt
    34081 ataaatttgg gacaggagat cctacacgat taggagctca agttatatca ggtgtgggtt
    34141 ttctaggcgc tggaacgatt cttattacag ataaaaagaa aattacaggt ctgacaactg
    34201 cagcaggcat ttgggcttcg gcaggaattg gattagctat tggagtaggt ttttatgagg
    34261 gagctctttt agtagccatt tctgtttggg gtgtgatatc catgttccaa ccactaaaaa
    34321 aatatctgca aaatcgttct aaaatgattg aattgtatat agtggttaaa tctacagaag
    34381 cctataatcg tgtattggtt tattgtgcag aaaatggtat cagaatgacc gattcaagaa
    34441 cagcgtttgg agatgttaat tctgacagaa ttgaatactt tgatgttccg gacaaaaaaa
    34501 tagcgtcatt tattactctg gaattatcag gtagatttga acatcttcga ctgatggaag
    34561 aaattgctaa tattgtaggt gttatttatg tcgaagaaat tagctgaaat ttagtaaaca
    34621 aagggacaga tgtttttgtc cttttgtttt ttagatgttt taatcatcta atttttgagt
    34681 agatttttgc tcagaggttt ttatgaaaga ttataaaatc aattttgatt taggtaaaat
    34741 agaatatttg ataataattg tttgatacaa gtatacaaat ttatttcttt ttatgatatt
    34801 tgtgaaatgg tgtttgcctt tcatttacct cctgatgagt tgataacaaa tgttatcttt
    34861 aaagaaaaaa ttaactctat gttaaaatgt tacattgaca ggctattata tgtttttata
    34921 aatcctacac attttactga aaaagttaat ctacaatttt atggcagttt tttctcatat
    34981 gaatttattt gtcgtgaagt tggaaacatt cttaaaaata aaggtgtgaa atgcaattta
    35041 aacttttttg aagggaaaga atatttgtaa aattaatttt gtgaatttgt ggatcttaaa
    35101 taatttacta aattctcttg ttaaaaaaaa ttaaatattg tatagtaata ttagaatgtt
    35161 cgtaatggag gactgaaatg aaaaatataa atgggaaaaa ggtaactatt tatgatattg
    35221 cacgtttatc aggtttttct ccaaaaacag tttcacgagt tattaatggt ggagtaaatg
    35281 ttaaagaaga aacttatcaa gcgattcaaa aagttataga ggaattgtcg tatattccaa
    35341 atgcgtatgc aaaaaattta actaaaaaag aagctataaa tatattgatt tctgtaaaaa
    35401 aaatcgactc ttttccttta atttggtttc atacgctgtt agataaagtg ttacggacgt
    35461 gtaaagaatt tggtgttaat gctatagttg agtactttgg agaggaggat acaattagta
    35521 attcaattat atcaagcaca ggtagcctag tagatggtgt tattgttttt tatgaaagtg
    35581 tagatgatat cagaattcag tatttaaaga agaaccatat gccttttctt gttttcggtg
    35641 aatctcaaac gtctggagta gtctatgtat ctaataataa ttttcaagct acttatgata
    35701 tgatgaaagc tgtaactgaa gaaaaattta aaaatatgtg gttgcttatg ggaggagaat
    35761 cccatgttaa taaggatcgt gaaagaggtg tgcgttcttt tctgaatgat aaaaattact
    35821 ttatggattt aaaagtcatt tatggcttat ctacaattga ttcagtttat tcttatgcaa
    35881 tgcagcactt gactacccaa aattatccgg acattatttt tgtttcagga gatgaaaagg
    35941 ttcagggctt gattcgtgcg tgctatgaga aaggaattct tattccagat gatatttcta
    36001 tcattggatt tgataatatt cctatttctc agtattatac tccagctttg tctacaattg
    36061 ctcccaatta tgttaaattg gctaaagaaa tgatagaagg tgttttagca attattaaag
    36121 gggaaagtgt cacatctgtt gaagtttctc ctaaatttgt taggagacag agtttctagt
    36181 attgtttaat tcttgaaaat cctagtggaa aagatggagt gttctaaaat aagttctgtt
    36241 tagcctccat tcagtttcta ttgagttgga tccaatttta acaagtggga catgttcatg
    36301 ttcgatctaa ggaagacatg gtcacattcg aatgatattt tcaaaaaaat cgtaaaaaag
    36361 tcttgacaaa gaaaaaacaa agtattaaaa taagttcaac aaatcagaaa agtaactatt
    36421 tttgatcttc agggagcctg tggtgattgt gaataggtgg ttggaagtag tgaaagtggg
    36481 ctgattttga aaatgaattt gaaacaatga aaattcggtg cgcacacctt acagtgcagc
    36541 ttgttgttaa acaaggcaga gatgtaaagg gatagtccct ttataattga ggtggcaccg
    36601 cgttaccaac gccctcacac ggaagtatat tctgtgtgtg ggcttttttc tatccgtcgt
    36661 ttggtttatc ttttattagg gccttaagtc gctttgatga acttgagttc tatctacagc
    36721 tccttgccta ctactaaaag caaacaaaaa ggctggacta atacgaaaaa agctagtaat
    36781 actcaatgaa aatcaaagag caaactagga aactagccgc aggttgctca aaacactgtt
    36841 ttgaggttgc agatagaact gacgaagtca gtaaccatac ctacgataag gcgacgttga
    36901 cgcggtttga agagattttc gaagagtata aaggtgtacc gagatgaaca tctcttcatc
    36961 aatgtctctg gtcgtggagg caaggaccta gctgcgattg cagattacta gaagctaaaa
    37021 aataatagat ggaaaaatta cagtcttttc tctcacagag agcttgtggt tgctgaaaac
    37081 aagcagagaa agctgtaaag ttgggttcat ctgaaacgag agaagaaaac atcattctca
    37141 agggagtgcc ctttatcgca cagcctgtta caggagatat ctgagacagg aatgagagat
    37201 aggagaaatc ctataattga ggtggcaccg cgaatttcgt cctcacgcaa gttattttgc
    37261 gtggggattt ttcatacagt caccacggac tagaagtaga actgaaaggg aaattacaat
    37321 ggaacgaatc attcatggag atgtcttatc accaatcttg gcttatatgc gcttaaaggg
    37381 gcaacataag gttattttag agagtattcc gagagacaag gaaacagctc gtttttctat
    37441 cctagcctat aatccagttt ttgagattaa gtttgaaaat ggggttctct atcaaaatgg
    37501 tcaagtgatt gatcgggatc ccttggattt cctttatgaa gtgattcata agagtcagca
    37561 ccactcagag ctaccttttg gtggtggagc cattggtttt gtgggttacg atatgatttc
    37621 gctttatgaa gaaattggtc aaatccctga ggatacaatt gggacgccag acatgcattt
    37681 ctttgtctat gagagctata tggtctttga ccacaagaag gagaagatac atgtcataga
    37741 ggatgcactt tatagtgagc gcagtcaaga ggccttggaa aaatccttga accaagtgct
    37801 tgaggaatta cgcattcctg ctccaaatga atttgaagat ttggatctat ctccgttaga
    37861 cttcaaaccg catatcgctc cacataagtt tgagggaatg gtagaaacag ctcgtgactt
    37921 gattcgtaac ggagatatgt tccaatgtgt actcagccag cgtttttcag cagaagttac
    37981 tggaaatcca tttgacttct acagaaatct ccgcgtgact aatccttcta attaccttta
    38041 tttctatgat tttggggatt atcaaatcat cggagctagt ccagaaagtt tagtttctgt
    38101 caaaaatggc atcgtgacaa ccaatccgat tgcagggacg cgaccaagag gggctacgga
    38161 tgaagaagac aagaccttgg cgactgacct cctctctgat gagaaggaaa cagcagaaca
    38221 tcgaatgttg gtagacttgg ggcgtaacga tattggccgc atctctgaaa cggccagtgt
    38281 ccaagttact aagtatatga aggtggagct cttccgctac gtcatgcatt tgaccagcgt
    38341 ggtcaagggg cgtttgcttc cagaactcac ggccatggat gccttgaaag ctacacttcc
    38401 tgctggaacc gtttctggag caccaaagat tcgggcgatg agacgcatct atgaactgga
    38461 aacggaaaaa cggggcgtat atgcaggagc aatcggctac ttgtctgcga cgggtgatat
    38521 ggatttggcc attgccatcc gaaccatgat tctcaaaaat caaagagcct atgtgcaggc
    38581 tggggcaggg attgtctacg actctatcgc ccaaaacgaa taccaagaaa ccattaacaa
    38641 agcaaaatct atgactagaa ttggagaact aagaccatga ttttattgat tgacaactat
    38701 gattctttta cctataactt ggcccaatac attgggaatt ttgcagaagt tcaggttctg
    38761 agaaatgatg attccaagct gtatgaagaa gctgaaaaag cagatggtct ggtcttttct
    38821 cctggtcctg gttggccagt tgatgctgga aagatggaag acatgattcg tgactttgca
    38881 ggcaagaagc cgattctagg gatttgttta ggccaccaag ccattgcaga agtctttggt
    38941 ggtaagctag gtttggctcc aaaagtcatg catgggaaac agagcaatat caactttgaa
    39001 gcgccatctg ttttgtatca aggtattgag gatgaccgtg cggtcatgcg ttatcacagt
    39061 attttgattg aggaaatgcc agaagacttt gaagtgacag ctcgttcgac tgatgaccaa
    39121 gccatcatgg ggattcaaca taaaaaccta ccgatttatg gcttccagta ccatccagag
    39181 agcattggaa cgccagacgg cttgtcttct attcggaatt ttatcgagaa ggttgtaaag
    39241 tgaggaaact aggatgaaag agattattga aaaactagca aaatttgaaa atttatcagg
    39301 tgtggaaatg acggatgtca ttgagcgtat cgtaactggg cgtgtaactg aagcgcagat
    39361 tgcttctctc ctcttagctc ttaagatgaa gggggaaaca cctgaagaac gcacagccat
    39421 tgcccaagtc atgagaggac atgcccagca tattccaact gagattcatg atgccatgga
    39481 caactgtggt acaggtgggg acaagtcttt cagttttaat atttccacaa ctgcagcctt
    39541 tgtcttggct ggtggcggta ttcacatggc caagcatggt aaccgctcga tttcttctaa
    39601 atctggttcc gcagatgtcc tcgaagcctt gggaatcaat cttgacctca aaccagctga
    39661 actaggtaag gtctttgata aaactggcat cgtctttctc ttcgctaaaa atatgcaccc
    39721 agctatgaaa tacatcatgc cagctcgttt ggaattggga attccaacga ttatgaactt
    39781 gactggtcca ctgattcatc caatggcttt agaaacacag cttcttggaa ttagtcgtcc
    39841 agaactccta gaaagtacag ctcaggtttt gaaaaatatg ggtcgcaaac gtgccatcgt
    39901 ggttgctgga ccagaagggt tggatgaagc tggcttgaac ggaacaacca agattgcact
    39961 tcttgaaaat ggcgaaatca gcttgtcaag ctttactcca gaggatttgg gaatggaagg
    40021 ctatgctatg gaagatattc gtggtgggaa tgctcaggaa aatgcagaaa ttttgcttag
    40081 cgttctgaaa aacgaagcaa gtccattctt ggaaacgaca gtcttgaatg ctggtcttgg
    40141 tttctatgct aatggtaaga ttgatagcat caaggaagga gttgccttgg cccgtcaagt
    40201 gattgctaga ggcaaggccc ttgaaaaact cagactgtta caggagtacc aaaaatgagt
    40261 caggaatttt tagcacgaat cttagagcag aaggcgcgtg aggtggagca gatgaagctg
    40321 gagcaaatcc agcctctgcg ccagacctat cgcttggcag aatttttgaa gaatcatcag
    40381 gaccgcttgc aggtaatcgc tgaggtcaag aaagctagcc ctagtttggg agatatcaat
    40441 ctcgatgtgg atattgtgca acaggcccag acttatgaag aaaacggagc agtgatgatt
    40501 tcggtgttga cagatgaggt tttctttaaa gggcatttgg attatctacg ggaaatttcc
    40561 agtcaggtag agattccgac gctcaacaaa gactttatca tagatgaaaa gcaaattatc
    40621 cgcgctcgca atgcaggtgc gacagttatc ttgctcattg tggcagcctt ggcagaagaa
    40681 cgtcttaagg aactttacga ctacgcgaca gagcttggtc tggaagtctt agtggagact
    40741 cacaatctag ctgaactaga ggtagcccac agacttggtg ctgagattat cggggtcaac
    40801 aaccgcaact tgactacctt tgaggtcgac ttgcagacca gtgtagattt agccccttac
    40861 tttgaggaag gtcgctatta catttctgaa tctgccattt tcacagggca ggatgcggaa
    40921 cgactagccc catactttaa cggaattttg gtagggacag ctcttatgca ggcagaaaat
    40981 gtggtccaga gaatcaagga gttgcagatt gacaaaggtt aagatttgtg gactatcgac
    41041 caaagaagcg gtggaaacag ccgtttcagc aggagccgac tatatcggtt ttgtcttcgc
    41101 acctagtaaa agacaggtga ctttagaaga ggcagctgag ttggcaaagc ttattcctgc
    41161 agatgtgaaa aaggttggag tatttgtttc accaagtcgg gtagaactgc tggaagcgat
    41221 tgacaaagtt agcttggact tggttcaagt tcacggtcag gtggcagatg atttatttga
    41281 gaatttgcct tgtgccagta ttcaggctgt gcaggtagat ggaaatgggc atgtccccaa
    41341 ttctcaggca gattatctac tctttgatgc ccctgtggca ggaagtggtc agtcctttga
    41401 ttggggtcaa ctggatacga ctggactagc acagcccttc tttatcgcag gtggccttaa
    41461 tgaagataat gtagtaaaag caattcaaca ttttactccc tatgcagtag atgtatcgag
    41521 cggagtggag acagatggac aaaaagatca tgaaaagatt agaagattta tagagagggt
    41581 aaagcatggc atatcaggaa ccaaataaag atggatttta cggaaaattc ggcggacgtt
    41641 ttgtcccaga aacattgatg acagcagttt tggagttgga gaaggcctac cgtgaaagtc
    41701 aggcagaccc aagtttccaa gaggaattaa accaactttt gcgccagtat gtgggacgtg
    41761 aaactcccct ttactacgca aaaaacttga cccagcatat cggcggagcc aagatttatc
    41821 tcaaacggga agaccttaac catacaggag cccacaagat taacaatgcc ttaggacaag
    41881 tttggcttgc caaacgtatg ggtaaaaaga aaattatcgc agaaactggt gctggtcagc
    41941 acggtgtggc aactgcaact gctgcggccc tctttaacat ggaatgtacc atctacatgg
    42001 gtgaggaaga tgtcaaacgc caagccctca atgtcttccg tatggagctt ttgggagcta
    42061 aggtcgaggc cgtgacagat ggttcgcgcg tgctcaagga tgcggtcaat gcagctcttc
    42121 gttcatgggt ggctaatata gatgataccc actatatcct tggttctgcc ttggggcctc
    42181 atccatttcc agaaattgtt cgtgacttcc aaagtgtcat tggtcgagag gctaaacaac
    42241 agtaccgtga cttgacagga caaaatctgc cagatgccct agtagcctgt gttggtggtg
    42301 ggtcgaatgc catcggtctc ttccatccct ttgtagaaga tgagtcagta gccatgtatg
    42361 gagctgaagc ggctggattt ggtgtggata cggagcacca cgcagctacc ttgaacaagg
    42421 gtcgtccagg tgtccttcac ggttccctca tggatgtgct ccaagatgcc catggtcaaa
    42481 ttcttgaagc cttctctatc tcagcaggtt tggactatcc tggtatcggt ccagagcatt
    42541 ctcactacca cgatattaaa cgtgccagct atgtccctgt gacagacgaa gaagccttgg
    42601 aaggattcca actcttgtct cgtgtggaag ggattatccc agctttggaa tctagccatg
    42661 ctatcgcttt tgcggtgaaa ttggccaaag aacttggacc agaaaagtct atgattgtct
    42721 gcctatcagg tcgtggggac aaggatgtgg ttcaagtcaa ggaccgcttg gaagcagatg
    42781 cagcaaagaa gggagaagct catgcctaag acactaacaa aaaaattaaa tgctattaaa
    42841 gcagctggaa aaggaatttt tgttccctat atcatggctg gtgaccacga aaaaggtttg
    42901 gatggtcttg ctgaaacaat tcacttttta gaagatttgg gtgtctctgc aattgaagtg
    42961 ggtattccct tttcagaccc tgttgcagat ggacctgtta tcgaagaagc tggcttgcgc
    43021 agtttagccc acgggacctc tacccaggct ttagttgaaa ccttgaaaac cattgaaaca
    43081 gagattccac tggtcatcat gacctacttc aaccccctct ttcagtacgg tgtggagaac
    43141 tttgtcaaag atctggctga tacagctgtg aagggcttga ttatcccaga cctgcctcat
    43201 gaacatgcca actttgtaga accatttttg gcagatacag atatcgcctt gattccttta
    43261 gtaagtttga ccacaggaat tgagcgccag aaagagttga ttgaaggggc ggagggattc
    43321 gtctatgccg ttgccatcaa tggggtgaca gggaaatcag gcaattaccg tgcagatttg
    43381 gacaagcact tggcgcaact tcatcaagtg gccgacatcc cagtcttgac aggttttggt
    43441 gtatctagtc aagtcgatct ggaacgcttc aatgcggtgt cagatggtgt tatcgtcggt
    43501 tcgaaaatag taaaagctct ccaccaagga gagccgattc agga
//
LOCUS       DAVHBD010000015        43225 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000015 DAVHBD010000000
VERSION     DAVHBD010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43225
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.015"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            16..86
                     /locus_tag="VVK04_000827"
     tRNA            16..86
                     /locus_tag="VVK04_000827"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Gly,seq:tcc)
     gene            122..195
                     /locus_tag="VVK04_000828"
     tRNA            122..195
                     /locus_tag="VVK04_000828"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Ile,seq:gat)
     gene            202..289
                     /locus_tag="VVK04_000829"
     tRNA            202..289
                     /locus_tag="VVK04_000829"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Ser,seq:gct)
     gene            complement(415..1350)
                     /locus_tag="VVK04_000830"
     CDS             complement(415..1350)
                     /locus_tag="VVK04_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU3989508.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1347..2207)
                     /locus_tag="VVK04_000831"
     CDS             complement(1347..2207)
                     /locus_tag="VVK04_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU3989509.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2315..4477
                     /locus_tag="VVK04_000832"
     CDS             2315..4477
                     /locus_tag="VVK04_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU3989510.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYENQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            4512..5771
                     /locus_tag="VVK04_000833"
     CDS             4512..5771
                     /locus_tag="VVK04_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU3989511.1"
                     /translation="MEWYKKIGLLATTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTV
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5785..6651
                     /locus_tag="VVK04_000834"
     CDS             5785..6651
                     /locus_tag="VVK04_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU3989512.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTRWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6665..7498
                     /locus_tag="VVK04_000835"
     CDS             6665..7498
                     /locus_tag="VVK04_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU3989513.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7499..7579
                     /locus_tag="VVK04_000836"
                     /pseudo
     CDS             7499..7579
                     /locus_tag="VVK04_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7856..9298
                     /gene="gtfA"
                     /locus_tag="VVK04_000837"
     CDS             7856..9298
                     /gene="gtfA"
                     /locus_tag="VVK04_000837"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU3989514.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVTF"
     gene            9436..10629
                     /locus_tag="VVK04_000838"
     CDS             9436..10629
                     /locus_tag="VVK04_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU3989515.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVFCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHALYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11315..13294
                     /locus_tag="VVK04_000839"
     CDS             11315..13294
                     /locus_tag="VVK04_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3989516.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13361..14857
                     /locus_tag="VVK04_000840"
     CDS             13361..14857
                     /locus_tag="VVK04_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989517.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14857..15783
                     /locus_tag="VVK04_000841"
     CDS             14857..15783
                     /locus_tag="VVK04_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989518.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15792..16859
                     /locus_tag="VVK04_000842"
     CDS             15792..16859
                     /locus_tag="VVK04_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989519.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16870..17796
                     /locus_tag="VVK04_000843"
     CDS             16870..17796
                     /locus_tag="VVK04_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989520.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            18414..19223
                     /locus_tag="VVK04_000844"
                     /pseudo
     CDS             18414..19223
                     /locus_tag="VVK04_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            19235..20128
                     /locus_tag="VVK04_000845"
     CDS             19235..20128
                     /locus_tag="VVK04_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989521.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            20141..20944
                     /locus_tag="VVK04_000846"
     CDS             20141..20944
                     /locus_tag="VVK04_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3989522.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQNPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20977..21687)
                     /gene="treR"
                     /locus_tag="VVK04_000847"
     CDS             complement(20977..21687)
                     /gene="treR"
                     /locus_tag="VVK04_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU3989523.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21872..23839
                     /gene="treP"
                     /locus_tag="VVK04_000848"
     CDS             21872..23839
                     /gene="treP"
                     /locus_tag="VVK04_000848"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU3989524.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTINRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFLFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24017..25642
                     /gene="treC"
                     /locus_tag="VVK04_000849"
     CDS             24017..25642
                     /gene="treC"
                     /locus_tag="VVK04_000849"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU3989525.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25898..26146
                     /locus_tag="VVK04_000850"
     CDS             25898..26146
                     /locus_tag="VVK04_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU3989526.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26353..27147
                     /gene="racE"
                     /locus_tag="VVK04_000851"
     CDS             26353..27147
                     /gene="racE"
                     /locus_tag="VVK04_000851"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU3989527.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27144..28115
                     /locus_tag="VVK04_000852"
     CDS             27144..28115
                     /locus_tag="VVK04_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU3989528.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28091..28612
                     /locus_tag="VVK04_000853"
     CDS             28091..28612
                     /locus_tag="VVK04_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU3989529.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28609..29070
                     /locus_tag="VVK04_000854"
     CDS             28609..29070
                     /locus_tag="VVK04_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU3989530.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29061..29801
                     /gene="xerD"
                     /locus_tag="VVK04_000855"
     CDS             29061..29801
                     /gene="xerD"
                     /locus_tag="VVK04_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU3989531.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29801..30529
                     /locus_tag="VVK04_000856"
     CDS             29801..30529
                     /locus_tag="VVK04_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU3989532.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TIFRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30548..31117
                     /locus_tag="VVK04_000857"
     CDS             30548..31117
                     /locus_tag="VVK04_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU3989533.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQALDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31104..31826
                     /locus_tag="VVK04_000858"
     CDS             31104..31826
                     /locus_tag="VVK04_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU3989534.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31826..32068
                     /gene="yidD"
                     /locus_tag="VVK04_000859"
     CDS             31826..32068
                     /gene="yidD"
                     /locus_tag="VVK04_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU3989535.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(32293..33258)
                     /locus_tag="VVK04_000860"
     CDS             complement(32293..33258)
                     /locus_tag="VVK04_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3989536.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33354..34106)
                     /locus_tag="VVK04_000861"
     CDS             complement(33354..34106)
                     /locus_tag="VVK04_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3989537.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(34103..35059)
                     /locus_tag="VVK04_000862"
     CDS             complement(34103..35059)
                     /locus_tag="VVK04_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU3989538.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(35049..36008)
                     /locus_tag="VVK04_000863"
     CDS             complement(35049..36008)
                     /locus_tag="VVK04_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989539.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36431..37132)
                     /gene="galE"
                     /locus_tag="VVK04_000864"
     CDS             complement(36431..37132)
                     /gene="galE"
                     /locus_tag="VVK04_000864"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU3989540.1"
                     /translation="MTKTILVTGETGYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLV"
     gene            37533..38597
                     /gene="pepA"
                     /locus_tag="VVK04_000865"
     CDS             37533..38597
                     /gene="pepA"
                     /locus_tag="VVK04_000865"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU3989541.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38619..38915
                     /locus_tag="VVK04_000866"
     CDS             38619..38915
                     /locus_tag="VVK04_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU3989542.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39597..40040
                     /locus_tag="VVK04_000867"
     CDS             39597..40040
                     /locus_tag="VVK04_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU3989543.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            40044..40808
                     /locus_tag="VVK04_000868"
     CDS             40044..40808
                     /locus_tag="VVK04_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU3989544.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     CIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40823..41551
                     /locus_tag="VVK04_000869"
     CDS             40823..41551
                     /locus_tag="VVK04_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989545.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            41544..43064
                     /locus_tag="VVK04_000870"
     CDS             41544..43064
                     /locus_tag="VVK04_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU3989546.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTV
                     LLSLSYSPALLVQKEKENVIIAGKIGPEPEILANMYKLLIEENTSLTATVKPNFGKTT
                     FLYEALKSGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVSTLEPALRYQAIQSGEIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELETVLNKLAGKITESQMSQLNYQVGVEGKPAEQVAKEFLQEQGLLKK"
BASE COUNT        12554 a         8014 c         9683 g        12974 t
ORIGIN      
        1 attgatagta tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt
       61 cgcgagttcg attctcgtca cccgctttga actttgttca aattaccaag ttttttaact
      121 tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga
      181 gtccactcgt gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa
      241 atcgttaggt cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga
      301 gtttgtaact ctctttttta tttttagaga caataaagct tcagatccgt aaaacttaat
      361 tgaattacta atctgaagtt atttttatat cgtttatatt ataattgtgt tattttactt
      421 ccaactattg agagaaattt cgccactatt tagccagatt tcttttccgt tatcacattg
      481 aactaaaagt tttccatttt ctgagatgtc tttagcaagt cccttgtagt ctttttgctc
      541 tagtgtgaaa gtgacttctt ttcctagaat gaatgactgt tttttgtata ggtataatag
      601 ctcttctgct ggtgtttcga agaaagcacg ccagatttct atgatcaatt cattccttgt
      661 tataggagct gtagctttaa ataagctggc agctttttct tttaattcct gagggaagtc
      721 tttaatagtg aaattgatac ctactccaat aatgatatct gtgactaagc cagtttctac
      781 agaggtcatt gcttcagtaa ggattcctcc aattttatga ttgtttagat agatatcatt
      841 gacccatttt atgtcgacat ctattaaagt taggttctta atggctttgt agacagctcc
      901 agctacaagt agtgtgtagg atggtaattt gtcatagggg agatttggtt taagatggag
      961 tgtcatataa ataccacctt gtggtgagta gaaggaacgt tgaaaacggc ctcggcctgc
     1021 tgtttgatag gaagctagat agagggtatt tgcttcatgg cctaaatcaa ttgcttcttt
     1081 tgcatctagt tgtgttgatt ttgtttcggg tttaaagctg actttaattg gaagattttc
     1141 ttctagaatc tctggaagaa taaggtcacc attcatcagt ttatatcctc tatttttgat
     1201 actatcaatt tcaatgcctt cttgttctag tcgcttgatg gctttccaaa ttgctgttcg
     1261 gcttagggat agtttttctg cgattttttc tccgctgata tagtcggttt ctttagatag
     1321 gatttggtag acagcttggt aggatttcat aatgttgcct ttcttactag ttggtattga
     1381 gagtattctt ttcttgtatg acttggagtc tgattaaagt attgtttata agctttcgaa
     1441 aaatggagtg gatctgaaaa acctaccgag tatgcaatta ccttgatgga ctcttgggta
     1501 ttttcgagaa gttgtctagc tcggtgcatt cgaacgtaga gtaggtattc tttgggtgat
     1561 aaggtattaa attctttgaa tacgcttgat aagtagcttc tgtgaacgga tagttctttt
     1621 gctaaatctt gaattgtaag tgattgagga tagtggctat caattaatcg tttgcattca
     1681 agatagagtt ggtgggttga tgaaatattc ttttttttct gattgggagc aatagttccc
     1741 agatgaaaca tcagttcatg aagttgtccc atgatatgga gttgagctaa ttcacttgat
     1801 tttgtaatct gagcgaagcg gacaatgtct gagatgagtt ttgcagtagt ctgggtatga
     1861 caagtttcag attggatgag ataggattga tcagaaattt gggaaagagc aaaataatca
     1921 ggggctttcc ctccagtgat tcctaaccag tagtaggccc aaggttcttt actatctgct
     1981 tgataaaagg ttagttcctc tggttttaat agaaagaaat ctccttcttt taaatcaaca
     2041 attttaccct tgtaatgaaa ttttccttgt cctttagtaa tgtaatgtag gacgtatgta
     2101 tcacgaatgg ctggaccaaa agagtaatta ggtgtgcatt cctcatatcc ataaaagctt
     2161 agggcaaggt cgattgttcc agtctggtat tctgaaaaaa ctaacatgtg ctacctccta
     2221 cctaacattt taccatattc ttgagacatt tttctatttt ggaaagcgat ttcaggtgat
     2281 aaaatagagt caataaagtg atgaggtgaa gtaaatggga gttaggatag agaataatct
     2341 attttatgtt gagagtaaaa atctaagttt gattattgaa aatcgaaatg gctacttact
     2401 tttgaaacat ttaggaaaga ctattaagaa ctataaaggt tccaatagtg tttatgaacg
     2461 agaccatgcc ttttcaggaa atccaacagc tactaatcga acctttagtt tagatactca
     2521 acgtcaaatt tttggacaac atggcttagg agattttagg aaaccaacca tacaggttca
     2581 gcataatgta actgaagtaa cagactttcg atttgtagaa gcaaagattt taaaaggtca
     2641 gaatggtcca cagggcttac cttctccaca tagcatggac gatacagaga ctcttgtctt
     2701 aatgttagaa gattctaagg ctcaacttag tctgactttg tattatacta cttttaataa
     2761 tgatgcgact attgctagct acagtaaatt agataataat agtaatcagg aagttgtcat
     2821 ccataaagat ttttctttta tggctgattt tccagctgca gattacgaaa tagtaactct
     2881 gcagggtgct tatgctcgtg aaaagactgt tagacgtcaa caggtagaac aaggaatctt
     2941 ttcgattagt tcaaaccgag gtgcttctgg tcatgctcaa acaccagctc ttctactatg
     3001 cgaacaagga gtcacagagg atgctgggaa tgtgtttgct attcaactaa tgtatagtgg
     3061 caactttgaa gcttttgttc aaaaaaatca attgaatgaa gttcgggtgg ctattggcat
     3121 taatccagaa aacttttctt ggaagttagc ccctgaggaa tactttgaaa caccggtagc
     3181 tttagtgact cattcagatc agggattaac tggtattagt catgaaagtc agaattttgt
     3241 actgaagcac attatgctaa gtgaattttc taaaaaagaa cgtccaattc taatcaataa
     3301 ctgggaagct acttactttg actttcagag agaaaaactg ttagagttag cagatgaagc
     3361 taagaaagtt ggcattgaac tttttgtatt agatgatggt tggtttggca atcgttttga
     3421 tgataatcgt gctttaggtg attgggttgt taatgaggaa aaactgggtg gaagtctaga
     3481 aagtctgatt tcagctatcc atgaaagagg tttgcagttt ggactttggt tagaacccga
     3541 aatgatttct gtagatagtg atttgtatcg tcgacatcct gactgggcta ttcaggttcc
     3601 tgactatgag catacttatt ctcggaatca attagtactt aatcttgcca atcctcaggt
     3661 agtagaatac ttgaaaagtg tcttagatca actcctatct tatcatgaga ttgattacat
     3721 taaatgggat atgaaccgca atatcactaa gctagggaat ggattaactt atctagagac
     3781 acagatgcaa tctcatcagt acatgctggg gctttatgaa ctcgtttctt atctgacaga
     3841 gaagcacagc catattctct ttgagtcctg ctctggtggt ggtggacgaa atgatcttgg
     3901 tatgatacgc tatttcccac aagtctgggc tagtgataat actgatgcca ttgcacgttt
     3961 accaattcaa tacggttcat cctatttcta tccaaccatt tctatggggg ctcatgtgtc
     4021 agcagtaccg aatcatcaga tgggacgaat gacaccatta gaaacacgtg gccatgtagc
     4081 aatgatggga aatttgggct atgagcttga tttgacaaat ttatcagatg aagagaaagc
     4141 tacgattgct aatcaggtga acttgtataa agaattacga ccagtagttc agttaggaca
     4201 gcagtataga ctaattaatc ctgatactgt atccaatgaa gcagctgtac aatttaatta
     4261 cgaaaatcaa acgattgtaa cctacgttcg cgttttatct gttgtagaga ccatggaaac
     4321 aactttaaaa ttaaaagatt tggatgaaga gggactatat aaattacagg aaaatggcga
     4381 agtttactca ggtgcagaac taatgtatgc gggcctaact gttatcttat cccaaggaga
     4441 ttttttgagt agacagtata tttttagaag actatgataa gggtgtataa atttataaag
     4501 gaggctttct aatggaatgg tataaaaaaa tcggacttct tgcaactaca ggtttagctt
     4561 tggttgggct cggcgcttgc tccaactatg gtaaatctgc ggatggcaca gtgaccatcg
     4621 agtatttcaa ccagaaaaaa gaaatgacca aaaccttgga agaaatcact cgtgattttg
     4681 agaaggaaaa ccctaagatc aaggtcaaag tcgtcaatgt accaaatgct ggtgaagtat
     4741 tgaagacacg cgttctcgca ggagatgtgc ctgatgtggt caatatttac ccacagtcca
     4801 tcgaactgca agaatgggca aaagcaggtg tctttgaaga tttgagcaac aaagactacc
     4861 tgaaacgcgt gaaaaatggc tacgctgaaa aatatgctgt aaacgaaaaa gtttacaacg
     4921 ttccttttac agctaatgct tatggaattt actacaacaa agataaattc gaagaactgg
     4981 gcttgaaggt tcctgaaacc tgggatgaat ttgaacagtt agtcaaagat atcgttgcta
     5041 aaggacaaac accatttgga attgcaggtg cagatgcttg gacactcaat ggttacaatc
     5101 aattagcctt tgcgacagca acaggtggag gaaaagaagc aaatcaatac cttcgttatt
     5161 ctcaaccaaa tgccattaaa ttgtcggatc cgattatgaa agatgatatc aaggtcatgg
     5221 acatccttcg catcaatggc tctaagcaaa agaactggga aggtgctggc tataccgatg
     5281 ttatcggagc cttcgcacgt ggggatgtcc tcatgacacc aaatgggtct tgggcgatca
     5341 cagcgattaa tgaacaaaaa ccgaacttta agattgggac cttcatgatt ccaggaaaag
     5401 aaaaaggaca aagcttaacc gttggtgcgg gagacttggc atggtctatc tcagccacca
     5461 ccaaacatcc aaaagaagcc aatgcctttg tggaatatat gacccgtcca gaagtcatgc
     5521 aaaaatacta cgatgtggac ggatctccaa cagcgatcga aggggtcaaa caagcaggag
     5581 aagattcacc gcttgctggt atgaccgaat atgcctttac ggatcgtcac ttggtctggt
     5641 tgcaacaata ctggaccagt gaagcagact tccatacctt gaccgtgaac tatgtcttga
     5701 ccggtgataa acaaggcatg gtcaatgatt tgaatgcctt ctttaacccg atgaaagcgg
     5761 atgtggatta ggagtagaga gactatgaaa aaagtattac aaaaatattg ggcatgggct
     5821 tttgtggtca tccccctctt gttacaagca attttcttct atgtgccgat gtttcaagga
     5881 gccttttaca gttttaccaa ctggacagga ttgacttaca actacaaatt tgtcggctta
     5941 aacaacttta agctcctctt catggatcca aaattcatga atgcgattgg ctttaccgca
     6001 atcattacga ttgccatggt ggttggtgag attgcactcg ggatcttcat tgcgcgtgtc
     6061 ttgaactcta aaatcaaagg ccaaaccttc ttccgtgctt ggttcttctt cccagctgtt
     6121 ttatctggtt tgacagtggc tttgatcttc aagcaagtct tcaactacgg tcttccagcg
     6181 attgggaatg cccttcatat tgaatttctc caaaccagtc ttttagggac taggtgggga
     6241 gcaatctttg cggctgtctt tgtccttctt tggcaagggg tggctatgcc catcatcatc
     6301 ttcctagctg gtttgcaatc tattccaact gagattacag aggcagcaag gattgatggt
     6361 gcgactagca agcaagtttt ctggaacatt gaattgcctt acttgctacc aagtgtctct
     6421 atagtcttta tcctagccct aaaaggtggg ctgactgcct ttgaccaagt ctttgccatg
     6481 accggtggtg gtccaaacaa tgccacaacc tcacttgggc tcttggttta taactatgcc
     6541 tttaaaaaca accaattcgg ttatgccaat gccattgccg taatcttgtt cttcttaatt
     6601 gtagtgattt cgatcatcca attgagagta tctaagaaat ttgaaattta agaggagaag
     6661 catgatgaaa caagatgaaa gaaaagccct gattggcaaa tacattctat tgattctagg
     6721 atcggttctg attttagtgc cgctccttgc taccctcttt agttccttca aacccactaa
     6781 ggatattgta gataatttct ttggctttcc aaccaacttc acatgggaca actttagccg
     6841 tctcttagct gatgggattg gaggctatta ttggaactct gtcgtcatca ctgtcttgtc
     6901 tttacttgca gtaatgatct ttatccctat ggcagcctac tccatcgctc gcaatatgag
     6961 taaaagaaaa gcctttacca tcatgtatac cctcttaatc ctcggaatct tcgtaccttt
     7021 ccaagtcatc atgattccga ttacggttat gatgagtaaa ctcggtttgg ctaatacctt
     7081 tggtttgatc ttgctctact tgacctatgc gattccacag accctctttc tctatgttgg
     7141 ctatatcaaa atctcgattc cagaaagtct ggatgaagca gcagagatcg atggggctaa
     7201 tcaatttaca acctatttcc gcatcatctt cccaatgatg aaaccgatgc atgcgacaac
     7261 catgatcatc aatgcccttt ggttctggaa tgacttcatg ttgccactcc ttgtcttgaa
     7321 ccgggattcc aaaatgtgga ctctgccttt gttccaatac aactacgcag gccaatattt
     7381 caacgactac ggaccaagct ttgcctctta cgtggtcggc attatcagta tcaccattgt
     7441 ctatctcttc ttccaacgcc atatcatttc aggaatgagc aacggggcag tgaagtaata
     7501 ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggttgctcaa aacactgttt
     7561 tgaggttgtg gatgaaactg acgaagtcag taaccatacc tacggtaagg tgaagctgac
     7621 gtggtttgaa gagattttcg aatagtataa gaagagctca tggaatctat agtctttgac
     7681 acagaggaag agttcagctt gttgataatt ctatgtagaa aacaagaaag tagtactttg
     7741 tttatcacag tctatattag tacgagtttg atgataaata gagatttaaa atgaatttta
     7801 tttatgaagc cagatcatat gagacttggc ttcaattaga aaaaggagag taatgatgcc
     7861 aattcaaaat aaaaccatgt tgattaccta ttctgatagc cttggaaata atcttaaaga
     7921 cttatatgat aatttggaag agcattttgg agatgctatt ggaggagttc accttttacc
     7981 atttttccca tcaacaggtg atcgtggatt tgcgccagtt gactacgacg aagtggactc
     8041 agcttttggt gattgggagg atgttaagcg tttaggtgag agatattatc ttatgtttga
     8101 ttttatgatt aatcatattt ctcgtcaatc caagtattat aaggactatc aagaaaaaca
     8161 tgaagccagt gaatttaaag ctctcttttt aaactgggat aagttttggc cagaaaaccg
     8221 tccgacacag tctgatgtag atttaattta caagcgtaag gatcgtgcac caaagcaaga
     8281 gattgtgttt gaagatggtt cagtggaaca tttgtggaat acctttggtg aggagcagat
     8341 tgatcttgat gtgaccaaag aagtaactat ggaatttatc cgtaagacca ttcagcactt
     8401 ggcaagtaat gggtgtgatt tgattcgtct agatgccttt gcttatgcag tgaagaaatt
     8461 ggatactaat gatttctttg tggaaccaga tatttgggat ttattggaca aagttcgaga
     8521 tatagctgct gagtatggga cagagctttt acctgagatt catgaacact attcgattca
     8581 gtttaaaata gcagaccatg attactatgt ttatgatttt gctcttccaa tggtgacact
     8641 ttatactctt tacagttcca gaacagagcg tttggctaag tggttaaaga tgagcccgat
     8701 gaagcaattt acgacgctag atacccatga tgggattgga gtagtagatg tcaaggatat
     8761 cctgaccgat gaggagattg actatgcttc aaatgaactc tataaggttg gagccaatgt
     8821 caaacgtaag tattctagtg ccgagtataa caacttagat atctaccaaa tcaattcaac
     8881 ctactattca gcgcttggag atgatgatgt caagtatttt ctcgctcgtc taattcaagc
     8941 ttttgcccca ggtattcctc aggtttacta tgtgggtcta ttagcaggca agaatgactt
     9001 gaaattatta gaagaaacta aagaaggtcg aaatattaat cgtcattact atagcaacga
     9061 ggaaatagca aaagaagtgc aacgacctgt tgtgaaggcc cttctcaatc tattttcttt
     9121 ccgtaaccgt tcagaagcct ttgatctaga agggactact gagatagaga caccaacagc
     9181 tcacagcatt gtaatcaaac gtcaaaataa agataagtcc gtaacagcag tagtagaaat
     9241 tgatttgcaa aatcagactt atcgggtaat tgagaatgga gttgaagtaa cattttgaag
     9301 ccttgatatg gtggataaaa tagggttttt attttggaaa acgtttcctt tgttttcaaa
     9361 ttgctaaaaa agtggtacaa tataggatag cttactatta tctgaatcag ctgatttgga
     9421 gagaaaggat tcattttgaa atcaataggc tttattgaaa agctgaaggg gttgtctagt
     9481 aaagagctga ttttattggg aattatcctg agtatctttt taccctttta tctttttgta
     9541 gttgtattct gtttatatat tatcagtctg atttttacag gagacatgaa aagtattctt
     9601 cagaaaatgg gggagcatcc gatgctgctt ctttttctta gctatagtac tgttatatcc
     9661 attcttgcac aaaattggat gggtcttgtg gcttcagtag gaatgtttct atttactatt
     9721 ttctttttgc actatcagtc gattttatcc cataaattct ttcgattgat tttgcagttc
     9781 gtcttgtttg gtagtgtctt gtcagctgct tttgccagtt tagaacattt ccaaattgtg
     9841 aagaaattta actatgcttt tctttcaccc aatatgcagg tgtggcatca gaaccgggca
     9901 gaagtgacct tctttaatcc taattattat ggaattattt gttgtttctg tattatgatt
     9961 gctttctatc tgtttacaac gaccaagttg aattggttga aagtattctg tgtgattgca
    10021 ggctttgtta atctctttgg tttgaacttt actcaaaatc gaactgcctt tcctgctatt
    10081 atcgctggag caattatcta tctctttacg actattaaaa actggaaggc cttttggctt
    10141 agtattgggg tcttcgcgat tggtttgagt ttcctctttt ctagtgattt gggagttcga
    10201 atgggtactt tagactcttc tatggaagaa cgcatttcta tctgggatgc tgggatggcc
    10261 ttgtttaagc aaaatccttt ttggggtgaa gggccattga cctatatgca ctcttatcct
    10321 cggatacatg ctctttatca tgaacatgcc cacagtcttt atattgatac gattctgagt
    10381 tacggaattg tgggtaccat tttattagtt ttgtcttctg ttgctcctgt tcgcttgatg
    10441 atggatatga gtcaggagtc ggggaaacgt ccgattatcg gcctttatct atctttcctt
    10501 acagtggttg ctgtgcacgg aatttttgac ttggctctct tctggattca gtcaggcttt
    10561 attttcttgc tagttatgtg cagtattcca ttggagcatc gaatgttggt atcggacatg
    10621 acggattaag ttttataagt ttgaaatctt ctaccttggg taggagattt ttttatacga
    10681 tgggcatgtc gtgcatctga ggtgtaagtc ctctgtaggg atccactacc ggtgaataca
    10741 atagcgctcc ccaagcctga ctatcgtgag gtagcggatt aaaatggtct ggggatagat
    10801 cgttttaagt ctgacgcagg aaataagaat tgtcagagaa agcaatagtg aaatcgtagg
    10861 ctatgaatag aaacgtgata gcgaggagca tatagtggat aaggtagcga gaaattttaa
    10921 agtataaaag atagtcttaa tctatatatg taaatcacaa aagtaattga attcggaata
    10981 aggttggtgt gaaaagacat agtaaactga atcttgaata ctagaatgat acttctacaa
    11041 tattgttata atttaatttg aattccaaaa tcacattgtt ccgtccgtat ttcattttac
    11101 tgtatgtctt cctaagctcc aaaatttctg tgtcaaattt cctattttca ctgtagtctt
    11161 tgacacttcg aacgacaatt tgaatcatat attcaaaaaa aatgaaaaat ttgtgccaac
    11221 aagcctaaat attctgaaaa tttgtttgat ttttaatgga taatgtgata taatggttgt
    11281 caatctataa ttcacataaa cagaggagta gaaaatgaaa aaaaatcgtg tatttgctac
    11341 agcaggtctt gttttattag cagcaggtgt acttgcagca tgcagttctt caaaatcatc
    11401 tgattcatca gcccctaaag cttatggcta tgtttataca gcagacccag aaaccttgga
    11461 ctacctgatt tcaagtaaaa atagtacaac agtagtgact tcaaatggga ttgatggttt
    11521 attcactaac gataattacg gtaatcttgc tcctgcagtt gcagaggatt gggaagtctc
    11581 taaggatggt ttgacctaca cttataagat tcgtaaaggg gttaaatggt ttacctctga
    11641 tggagaagaa tatgcagagg tgacggctaa agatttcgtg aacggtttaa aacacgcagc
    11701 agataaaaaa tcagaagcta tgtatttagc tgaaaattcg gttaaaggct tggcagatta
    11761 tctatcagga acttcaacag atttttcaac agttggtgtc aaggcggttg atgattatac
    11821 gttacaatac actttgaacc agcctgaacc gttctggaac tctaagttga cctattctat
    11881 tttctggcct ctgaatgaag aattcgaaac atcaaaagga agcgattttg ctaaaccaac
    11941 agatccgaca tccttgcttt ataatggtcc attcttgttg aaagggttga ctgcaaaatc
    12001 ttctgtagag tttgtaaaaa atgagcaata ttgggataaa gaaaatgtcc acctagatac
    12061 tatcaatcta gcttactatg atggatcaga tcaggagtcg ctagagcgta acttcactag
    12121 tggagcttat agttatgccc gtctttaccc taccagctcc aactattcta aggttgcaga
    12181 agaatacaag gacaatatct attacacaca atcaggctct gggattgctg gtctgggtgt
    12241 gaatattgat cgccaaagtt acaactatac ttctaaaact acagattcag agaaagtagc
    12301 tactaagaag gcattgctta acaaagattt ccgtcaagcc ttgaattttg ctcttgatcg
    12361 ctcagcttac tcagctcaaa tcaatggtaa agatggagca gctttagcag ttcgtaattt
    12421 atttgtaaaa ccagactttg tttcagctgg tgagaagacc tttggtgatt tagtcgctgc
    12481 tcaacttcct gcttatggtg atgagtggaa aggtgtgaat ttagctgatg ggcaggatgg
    12541 tttattcaat gctgacaagg ccaaggcaga gtttgcgaaa gctaagaaag ctttagaagc
    12601 agacggcgtt cagtttccta ttcatctgga cgttccagta gaccaagcat caaaaaacta
    12661 catatctcgt attcagtcct ttaaacaatc tgtagaaaca gttcttggtg ttgaaaatgt
    12721 cgttgttgat attcaacaaa tgacaagtga tgaattcctt aatattactt actatgctgc
    12781 caatgcttca tctgaggatt gggatgtatc gggaggagtt tcatgggggc cagactatca
    12841 agacccatct acttacctgg atattttaaa aacaactagc agtgaaacta caaaaacata
    12901 tttaggattt gataatccaa atagcccttc agtagttcaa gttggtttga aagaatacga
    12961 taaattagtt gatgaagctg ccaaagagac aagcgacttg aatgtccgtt atgaaaaata
    13021 tgcagcggct caagcatggt tgacagatag ttcactcttt attcctgcta tggcttcttc
    13081 tggtgcagca ccagtgcttt cacgaattgt tccatttact ggagcttctg cgcaaacagg
    13141 ctctaagggg tcagatgttt acttcaaata tttgaaatta caagataaag cggtgactaa
    13201 ggaagagtat gaaaaagctc gtgaaaaatg gttgaaagaa aaagctgaat caaatgagaa
    13261 agctcaaaaa gaattggcaa gtcatgtgaa gtaaataatt tctaatagaa ctttctctcc
    13321 atgaggagaa ggttcttttg ggatttttaa aggaaataat atgaaaaaat atatttttat
    13381 gcgtgttttg cggtcattgg tttcgatttt cttagtaacg actttgacct acacgattat
    13441 ctataccttg gttcctcgaa aattgatttt caagcaggat cctaactata ataaaattgc
    13501 gacaacggct gataaacgtg ataactatga aaatactgtg tttgagcgta tgggctacat
    13561 tgagtattac gatactaaag agttgcaaga aaaggcaagt agcatggatt cttctgtaac
    13621 agtagaagca aatgcgacca ataaagctat ttatgaaaag tacatcaatc aattaggtca
    13681 tggttggact ttgggagaat ttactgaaag tggtcaattc tatgctactc gtgaaattcc
    13741 aatttttgaa cgtgtttttc acttctatgc taacttgatt gacattgacc atacaaataa
    13801 aatccaagac cctgaaaatc cagacttgaa acgctacctt cgttttgaaa atgatccagc
    13861 tatcggatgg tcattggtcg gttcaggaac taaacataaa tatctcttgt actttaacag
    13921 tcagttccca tttgttcatc aaaactttgt gaacttgaat ttaggtgact cttacccaac
    13981 ctatgctaat acaccagttc ttcaggttat tactcaaggt caaggacaaa ccaaaactgc
    14041 ccaagttcag ttcccaacag gtaagaaaac gtcttctgta aatatttact caagaaccta
    14101 caagtcacct agtcaggctg actctcgtga agtagctagc tatgggaaag atgatcctta
    14161 tacagcgact gaaagtaatt accaatatcc atctatgatt gtcagctctg ctattactgg
    14221 tttgattggt ttggttcttg cctatgctct tgccgtgcca cttggttcag ccatggctcg
    14281 tttcaagaac acttggattg atagcctctc aacagggact ttgaccttct tgcttgctct
    14341 tccaacgatt gccttggttt acatcgttcg attgattgga tcatctattg cccttccaga
    14401 ttcattccct atcttgggag ctggagattg gcgttcttac gttttaccag cagtcatcct
    14461 tggtttgttg ggtgctcctg ttacagccat ttggattcgt cgttacatga ttgacttgca
    14521 atctcaagac tttgttcgtt tcgctcgtgc aaaaggtttg tctgaaaaag aaatttcaaa
    14581 caaacacatc tttaaaaatg ccatggttcc gctggtttca ggaattcctg gtgccattat
    14641 tggggttatc ggtggtgcaa cccttactga aacagtcttc gccttcccag gtatgggtaa
    14701 aatgttgatt gactctgtaa aagcatctaa taactctatg gtcgttggtc ttgtcttcat
    14761 ctttacatgt atttctatct tctcacgtct tttgggagat atttggatga ctattattga
    14821 cccacgtatt aaattgactg agaaaggagg caaataatgt ctacaatcga taaagaaaaa
    14881 tttcagtttg taaaacgtga cgattttgcc tctgaaacta ttgatgcgcc agcatattct
    14941 tactggaaat cagtgtttaa acaatttatg aagaaaaaat caactgtagt catgttggga
    15001 atcttggtag ccatcatttt gataagtttc atctacccaa tgttttctaa gtttgatttc
    15061 aatgatgtca gcaaggtaaa cgactttagt gttcgttata tcaagccaaa tgcggagcat
    15121 tggttcggta ctgacagtaa cggtaaatcg ctctttgacg gtgtctggtt cggagctcgt
    15181 aactccatcc tcatttctgt gattgcgaca gtgattaact tggttatcgg tgtttttgtc
    15241 ggtggtattt ggggtatttc aaaatcagtt gaccgtgtca tgatggaagt ttacaacgtc
    15301 atctcaaaca tcccacctct tttgattgtt attgtcttga cttactcaat cggagctgga
    15361 ttctggaatc tgatttttgc catgagcgta acaacatgga ttggtattgc cttcatgatc
    15421 cgtgtgcaaa tcttgcgcta tcgtgacttg gaatacaact tggcgtcacg tactttggga
    15481 acaccaacct tgaagattgt tgccaaaaat atcatgcctc aattggtatc tgttattgtg
    15541 acaaccatga ctcaaatgct tccaagcttt atctcatacg aagccttctt gtctttcttc
    15601 ggtcttggat taccgattac agtgccaagt ttgggtcgtt tgatttcgga ttattcacaa
    15661 aacgtaacaa ccaatgctta cttgttctgg attccattga caacccttgt cttggtatcc
    15721 ttgtcccttt tcgtagttgg tcaaaactta gcggatgcta gtgatccacg tacacataga
    15781 taggagtaga aatgacaaaa gaaaaaaatg taattttgac tgctcgcgat attgtcgtgg
    15841 aatttgacgt tcgtgacaaa gtattgacag ccattcgcgg cgtttccctt gaactagtcg
    15901 aaggagaagt attagccttg gtaggtgagt caggatcagg taaatctgtt ttgacaaaga
    15961 ccttcacagg tatgctcgaa gaaaatggtc gtattgccca aggtagtatt gactaccgtg
    16021 gtcaggactt gacagcttta tcttctcaca aggattggga acaaattcgt ggtgctaaga
    16081 ttgcgactat cttccaggac ccaatgacta gtttggaccc cattaaaaca attggtagtc
    16141 agattacaga agttattgta aaacaccaag gaaaaacagc taaagaagcg aaagaattgg
    16201 ccattgacta catgaataag gttggcattc cagacgcaga tagacgtttt aatgaatacc
    16261 cattccaata ttctggagga atgcgtcaac gtatcgttat tgcgattgcc cttgcctgcc
    16321 gacctgatgt cttgatctgt gatgagccaa caactgcctt ggatgtaact attcaagctc
    16381 agattattga tttgctaaaa tctttacaaa acgagtatca tttcacaaca atctttatta
    16441 cccacgacct tggtgtggtg gcaagtattg cggataaggt agcggttatg tatgcaggag
    16501 aaatcgttga gtatggaacg gttgaggaag tcttctatga ccctcgccat ccatatacat
    16561 ggagtctctt gtctagcttg cctcagcttg ctgatgataa aggggatctt tactcaatcc
    16621 caggaacacc tccgtcactt tatactgacc tgaaagggga tgcttttgcc ttgcgttctg
    16681 actacgcaat gcagattgac ttcgaacaaa aagctcctca attctcagta tcaaagacac
    16741 attgggctaa aacttggctt cttcatgagg atgctccaaa agtagaaaaa ccagctgtga
    16801 ttgcaaatct ccatgataag atccgtgaaa aaatgggatt tgcccatctg gctgactagg
    16861 aggaaggaaa tgtctgaaaa attagtagaa atcaaagatt tagaaatttc cttcggtgaa
    16921 ggaagtaaga agtttgtcgc ggttaaaaat gctaacttct ttatcaacaa gggagaaact
    16981 ttctcgcttg taggtgagtc cggtagtggg aaaacaacta ttggtcgtgc tatcatcggt
    17041 ctaaatgata caagtaatgg agatatcatt tttgatggtc aaaagattaa tggtaagaaa
    17101 tcgcgtgaac aagctgcgga attgattcgt cgaatccaga tgattttcca agaccctgcc
    17161 gcaagtttga atgaacgtgc gactgttgat tatattattt ctgaaggtct ttacaatcac
    17221 cgtttattta aggatgaaga agaacgtaaa gagaaagttc aaagtattat ccgtgaagta
    17281 ggtcttcttg ctgagcactt gactcgttac cctcatgaat tctcaggcgg tcaacgtcaa
    17341 cgtatcggta ttgcccgtgc cttggtcatg caaccagact ttgttattgc agatgagcca
    17401 atttcagcct tggacgtttc tgtacgtgcc caagtcttga acttgctcaa aaaattccaa
    17461 aaagagctcg gcttgaccta tctcttcatc gcccatgact tgtcggttgt tcgctttatt
    17521 tcagatcgta tcgcagttat ttacaagggt gttattgtag aggttgcaga aacagaagaa
    17581 ttgtttaaca atccaattca cccatatact caagccttgc tttcagcagt accaatccca
    17641 gatccaatct tggaacgtaa gaaggtcttg aaggtttacg acccaagtca acacgactat
    17701 gagactgata agccgtctat ggtagaaatc cgtccaggtc actatgtttg ggcgaaccaa
    17761 accgaattgg cacgttatca aaaaggacta aactagtaat ggttttataa tttccatgtc
    17821 aatttttatg gaaattataa aacttttttt gttggactga tttgaaaaac tttgaaagct
    17881 tcctgaaaga attttcgaaa aattttaaaa attctgaaat attattgaca ggtgatgaaa
    17941 aaggtggtag gataggaagc atcaaaaaag aaagcagaaa aagaaatgaa taagagacaa
    18001 gccgtaacta tgaatcaaaa cttttacttt agctacttta gatagtgttt gtagacatgt
    18061 caccatggat gcaaacagtt caagcaattt gtttgtatct atgtggctaa gatttttgat
    18121 tgtggtccat atagatgaat atctaaatgg actagctaag ttgtaacttg ttaggttatt
    18181 tcaagtatcc gtttagatag tatctaggcg gttttttgtt ttatcttttc tgagaaggag
    18241 tttcattatg aaagttgttc gaaaatcact agccccctct tggtagtggg gctcctcttg
    18301 acttctctga tcagtttgca tcagttgaag gcagataaga aaaagatgtc tttcgtatcg
    18361 gtatttcgca atttattacc caccagtcct tagacgctac tagagaagaa tttgtggatg
    18421 agctggccaa acaaggctat gttgaggggg aaaatattga gattgatttg caaaatgcac
    18481 agggagaaca aagaaatcta aaaacgattt cccagcaact agcagaatcc agcgatgtcg
    18541 ttctagccat cgcaaggcct tctgctcaga gcttggccaa tacgacgcaa acgacaccag
    18601 ttatcttttc agctgtaaca gacccagtca gtgccaagtt ggttgagtca agagaacatc
    18661 ctgggggcaa tgtaactggg acaagcgatc agtcatcaga tgccatttca acccaaatca
    18721 atttgataaa gaaagtgttg ccaaaggcta aaacgattgg aatcctctat actcagagcg
    18781 agcccaattc ggttgttcaa aaggatgaag ctaagcgact tctgaaagaa aaaggcttta
    18841 ccgttgttga aaaaacaatc ttggacagta ataacgtcaa ggcggcagca gagagtttga
    18901 tggcagaggt ggatatggtt tttgtcccaa ctgataatat catttcgtta accatggaaa
    18961 cagttaagca ggtttctatt aaacacaagg ttccagtatt tggtggttca acagaaatga
    19021 ttgcggctgg tggcttgtat aactactgaa ccaattatga agaattggga agacagacag
    19081 ctcgcatgct gattcatgtt ttaaaaggtg agaaaccaga aaatatagca gttgagttgc
    19141 ctgaaaaact ggaattgcat actaatcaag aaatggcaga tgcattggga attgatatta
    19201 gtaagttaga aggcaaggaa taaggaggat taagatgaat tttgtgttat ctagtttatc
    19261 agaaggtttg ttgtggtcga ttgtggcgat tggggtctac ttgactttcc gtattttgga
    19321 tattgcggat atgactgctg agggagcctt tcctctgggg gcagcagtcg ttgtatcaca
    19381 gatacaggca ggggcaaatc cttggcttgc gactttactt gctttgctgg caggtatggt
    19441 agcaggtctt gtatcaggaa tgctccacac caagatgaaa atcccagctc tcttgacagg
    19501 gattgtgacc ttgacagggc tctattcaat caatattaaa atcatgggca gtgtacccaa
    19561 tctttccttg ggagattctg caaccgtctt taaacagttg gcgagcttgg gtctgacaaa
    19621 tgaaggaact gttttctcac ttagtttggc ctgtttttta cttgtttgtt tggtcttgac
    19681 ccttttgatg aaaacagaga ttggcttggt cttgcgttcg actggggata atatcccgat
    19741 gagtgaggcc aatggagtca atgtagacac catgaagatt gttggttaca tgatttcaaa
    19801 cggtttgatt gctctatgtg gttccttgtt tgcccaaaat gatggatttt cagatgtgac
    19861 ttctgggaca ggaaccattg ttgttggttt gagctcggtg attattgcgg aagtcttgat
    19921 acacgacttg accattggag gccgcttatt atccatcgga atcggtgcta ttgtttaccg
    19981 tttgattatt ttaaatatct atgaaattcc aaatctagat caaaacttgg tacgtctctt
    20041 taatgcaatc ttgctcgctt tggttttatt tgcaccagaa ttgcaaaaga gattaaagat
    20101 tcgtggtctg aaattgagaa atgaatagga ggagaaagtt atgacaagtt tgttaacact
    20161 tgaaaatatt cacaagacat ttgaagcagg gacggtcaat gagaaccatg tcctcaaagg
    20221 attagattta gaggttgaag agggagattt tatctctgtg attggtggaa atggagcagg
    20281 aaaatccact ttgatgaata tcttggctgg caatctatcg gtggacgaag gggaccttct
    20341 actggcaggg aaatccatta aaaatctgag tgtcagaaag agagccaagg atattgcccg
    20401 tgtttttcaa aatcctaaga tgggaacagc ttctcgtttg acgattgagg agaatatggc
    20461 tattgccttg agacgcgggc agaagagagg gcttggttgg ggcgtgaagg agaaggatag
    20521 aatccagttc caagaggcct tgaaggagtt gaatattggt cttgaaaacc gcttaaaagt
    20581 agatactcaa tatctctcag gaggacaaag acaggctttg actctagtca tgacagatct
    20641 gatgaaacca aaacttttac ttttggatga acatactgcg gcacttgacc cgaaaaccag
    20701 tcaaatggtg atggacttga cgcaaaagat tgtggagcac catcagtgga cgactttgat
    20761 gattacccat gatatgaatc atgcgattga gtacggcaat cgtctcatta tgctctatca
    20821 aggcaagata gtggtggatg tcaagggaga agagaaaaag catctgacag ttgaagacct
    20881 tatgcatctc ttccagaaaa atagtggcca aagtctggtc agtgatgaat tagttttggg
    20941 ataaagaaaa aggctgagat ctggtgtctc agtcttttat ttcttgcgtt ttgcaaaatc
    21001 tacaaatcta aatttctcta acttatggcg actttcggta aactgaaatt ggcgtccgtc
    21061 ttggagatag acttttgatt taatcgaaac gacataaggg tctttgccaa tgtccatgag
    21121 aatcttgtct cggtcgcttg agtggtcaat ggtgatttcc ttctgagcat aatcaataag
    21181 gagtttgagg ccattttcta tataagaata gatagactgc tcagcaattt ggcgagtgag
    21241 atttggaatt agttccatat ccagatagtc cgtatccaga acggatacca gatcatccac
    21301 cacacgctgg cggaccacct tccaaaccat ccgaaactct gggaaaccgg ttatcagtga
    21361 ggatttttta tcaataataa tcttgtccag actgaccacg ttggttttag agcgcagtcc
    21421 aagttcttta actagttctt ggtagctggt taggttggat acagggaaat tgacggtttc
    21481 ttctttgacg acttgagaac cttgccctct tatctttttg atcaatcctt cctcttggag
    21541 gagagacagg gcctttcgga cggtatcacg actcacttga tattgctcca taaggtcgtg
    21601 ctcgctagga aggaaatctc cgacagcgta agtctcgttt tgaatggttt cttggatttg
    21661 cttaaataat tgttggtatt tcttcatttt gcctgcttaa ataggttttt agtctagttt
    21721 aatgaacacc tgtatctatt ttaccataca agtgctagaa aatttacaaa aaaacaccct
    21781 ttttatacca aacaagttgc agacaagttt ggtatcgttt acaatatact tatcaaatca
    21841 aacttgcttt gacaagtata aggagaatca aatgggaaaa tttgaacaag aagccaaaga
    21901 tctgcttcag gcaatcggag gcaaagaaaa tgtgactgcc gtaactcact gtgcgacacg
    21961 gatgcggttt gttttaggag atgataagaa ggctaatgtt aaagctatcg agtcaattcc
    22021 agctgttaaa ggaaccttta caaatgcagg tcaatttcag gtaatcattg gaaatgacgt
    22081 gcccatcttt tataatgatt ttacagccgt ttcaggtatt gagggtgttt ccaaagaagc
    22141 agccaagtct gcagctaaga gtaatcaaaa cgtggtccaa cgtgttatga ccactctggc
    22201 ggaaatcttt actccgatta ttccagcctt gattgttggt ggattgatcc tcggtttccg
    22261 taatgtcttg gaaggtgtcc attggtcgat gttggatggc aagaccatca cagaatcctc
    22321 tcagttttgg gcaggggtta atcacttcct ctggttgcct ggtgaagcta tcttccagtt
    22381 cttaccagta gggattactt ggtctgtttc tcgtaagatg ggaaccagcc aaattttggg
    22441 aattgttctc ggaatctgtt tggtatcgcc tcagttgctc aatgcctatg cggttgcttc
    22501 aacgccagca gctgatatcg cggcaaactg ggtttggaat tttggctatt ttactattaa
    22561 tcgtatcggt taccaagccc aagttatccc agccttgctt gcaggtttga gtctgtctta
    22621 tcttgaaatc ttctggcgca agcatatccc agaagtcatt tctatgattt ttgtaccttt
    22681 cttgtcattg attccagcct tgattttggc tcatactgtt ttgggaccaa tcggttggac
    22741 aattggacaa ggactttcat cagttgtctt ggcaggttta actggtccag ttaaatggct
    22801 cttcggtgca atttttggtg ccctctacgc tccatttgtc atcacaggtc tgcaccatat
    22861 gaccaatgcc attgatacac aattgattgc ggatgctggt ggcactgccc tatggccaat
    22921 gattgctctt tctaatattg ctcaaggctc agccgtgttt gcctattatt tcatgcatcg
    22981 ccatgatgag cgtgaggctc aggtttcact tcctgcaacc atttcagcct atctcggtgt
    23041 tacagaacca gctctttttg gggttaacgt aaaatatatt tatccatttg ttgctgggat
    23101 gactggttca gcccttgcag gcatgttatc cgttactttt aatgtaactg cggcttctat
    23161 tggtatcggt ggtttgccag gtattctctc tattcaacct caatacatgc tgccatttgc
    23221 aggaactatg ctagttgcga ttgttgttcc aatgctcttg actttcttat tccgcaaggc
    23281 tggtctcttt acaaaaacag agggcgatac gaacttgcag gcagaattcg ttgctcaaga
    23341 agaagcagaa tttgtgaacc atgaaccagt agaacttact tcggtagaaa ttatcagccc
    23401 actaactggc caagtgaaag aattgagtca agcgacggat cctatttttg catcaggtgt
    23461 catggggcaa ggtctagtca ttgaaccaag ccaaggtgag ttgacctctc cagttaatgg
    23521 gacagtgacg gttcttttcc ctaccaagca tgccatcggc attgtctctg acgagggagt
    23581 tgaattgctc atccacatcg gtatggatac agtaggtctt gatggcaaag gttttgaaag
    23641 tcttgtagtc caaggagatc acgttacagt tggtcagcaa ctgattcgtt ttgatatgga
    23701 tgtcattaag gctgcaggtc tggtgacaga aactcctgtt atcatcacca accaagatgc
    23761 ttatacagcg actattcccg gaacttatcc gacaacgatc caagctggag catctctcat
    23821 ggtcgctaca cgaatctaat actcttcgaa aatctcttca aaccacgtca gctctatctg
    23881 caacctcaaa atagtgtttt gagcaacctg tggctagctt cctagtttgt tctttgattt
    23941 tcattgagta taattgaaat agcacaaata gggacggaag actgcttcct cccttttatc
    24001 agaaaaggag aaacagatga cacttgataa aggaaaagta gtctatcaaa tctatccaaa
    24061 atcttacaaa gacaccactg aaaacggtat tggggatttc cgtgggatta tcgaaaaaat
    24121 tccctattta gccaaactag gtgtggatat ggtctggctc aatccattct atccaagccc
    24181 tcaacgggat aatggttacg atatttcaga ttatatggca gtggatcctc tttttggtga
    24241 tatggctgat tttgaggaaa tggtgtgtgt cggtaaagag cacaagattg actttatgct
    24301 ggacatggta cttaatcatt gttcgacaga gcatgaatgg tttcagaaag ccctagctgg
    24361 tgataagtat tatcaagact ttttcttcat ccaagaccaa ccaacagatt ggcagtctaa
    24421 gtttggtggt tctgcatgga cgcctttcgg ggatactggg aaatactatc ttcacctatt
    24481 tgatgagacc caggctgacc ttaactggcg caattccaat gtccgtaagg agcttttcaa
    24541 ggttgttaat ttctggcgcg acaagggtgt caaaggtttc cgatttgatg tgatcaattt
    24601 gatcggtaag gacgaggttt cagtggactg tcctgaaaat gaagggaagc cagcttatac
    24661 agacaaaccc atcgttcata actatttgcg tatgatgaac caagccactt ttggatctga
    24721 cgatagcttt atgacagttg gggaaatgtc ttctaccacc atggaaaact gtgtcctcta
    24781 ttcgtcgcct gatcgtcagg aattatccat gacctttaat tttcatcacc tcaaggtgga
    24841 ctataaggat ggacaaaagt ggaccttggc tccctttgat tttgaagagt tgaagagtct
    24901 ttaccatagt tggggtaagg aaatgagtga taaagacggt tggagtgccc tcttttggaa
    24961 caatcacgat caaccacgtg ccttgaaccg ttttgtcgat attcaaaact tccgcaagga
    25021 aggagccacc atgctagcag ccagcattca cctgtcacgt gggacacctt atatctacat
    25081 gggtgaggaa atcgggatga ttgacccaga ctatgattct atggctgatt atgtggatgt
    25141 cgaatcgctt aatgcctatc agatgctctt agaagaagga aagagtcagc aagaagcctt
    25201 ccagattatt caagctaagt cgcgtgataa ttcacgcatt cccatgcagt gggatgcttc
    25261 ggaaaatgca ggattttcaa caggcactcc ttggttgaaa gctggtaaat cctataaata
    25321 catcaatgta gaaaatgaaa tccagggtcc gatttttacc ttctatcaag acttgattcg
    25381 actgcgtaag gaaatgccaa tcatttcaga aggaagttac aaaccagcct ttgaagatag
    25441 caaacaagtc tacgcttttg aacgccagtt tgaggatcaa aagttactag tgctcaataa
    25501 cttttatgct aaagaagtgg aaatcgactt gccagcagtc taccaaaatg gacagatttt
    25561 gatatcaaac tatgaagatg cagaagtgtc tgagaaaatt ctactcaaac cctatcaaac
    25621 actggctatt tatgtaaatt aatactcttc gaaaatctct tcaaaccgtg tcagttttat
    25681 ctgcaacctc aaagcggtgc tttgagcaac ctgtggctag cttcctagtt tgctctttga
    25741 ttttcattga gtataaactt agcaaggaga cctctttttc agaaaagcag ggttcttttt
    25801 gctgtctatt ccatccctga aagtgtagaa caaactggtc agggtggcta gtttgtggta
    25861 taatgaaagg gactcaaaaa gaaacaggag aaaaatgatg gatttacttt tagcaattgt
    25921 attgattgtg ctagcttttc taggaggagc tctaggagga atgtacttgg ttcgtaagca
    25981 aatcgaaaaa gaatttgctg acaacccacg tttgaatgct gaagcagttc gtactctttt
    26041 gagtgcaaat ggtcaaaaac caagcgaagc taaggtacaa caagtttacc accaaatcat
    26101 ccgccaacaa aaggcagccc ttgctaacaa taaaaagaaa aaataaataa ggaaaagtct
    26161 gggatgaaag ttccagactt ctcactatgt tggttatggt ttagggatga gactttttcc
    26221 ttgcattcta ttgatatttg attatgatta agagagaggt agttgacatt ctatcaagct
    26281 gtcggtcagt tcgttcagta caaggaatca taatgaacga tcaatcagaa aaaagactag
    26341 aaagaagact gtatggataa tcgaccaatt ggttttttgg attcgggtgt cgggggcttg
    26401 accgttgtgc gcgagctcat gcgccagctt ccccatgaag aaatcgtcta tattggagat
    26461 tcggcgcggg cgccctatgg cccccgtcct gctgagcaaa ttcgtgaata tacttggcag
    26521 ctggtcaact ttctcttgac caaggatgtc aaaatgattg tcattgcttg taacactgcg
    26581 actgcggtcg tctgggaaga aatcaaggct caactagata ttcctgtctt gggtgtaatt
    26641 ttgccaggag cttcggcagc catcaagtcc agtcaaggtg ggaaaatcgg agtgattgga
    26701 acgcccatga cggtacaatc agacatatac cgtcagaaaa tccatgatct ggatcccgac
    26761 ttacaggtgg agagcttggc ctgtcccaag tttgctccct tggttgagtc aggtgccctg
    26821 tcaaccagtg ttaccaagaa ggtggtctat gaaaccctgc gtcccttggt tggaaaggtg
    26881 gatagcctga ttttgggctg tactcattat ccactccttc gccctattat ccaaaatgtc
    26941 atggggccaa aggttcagct catcgatagt ggggcagagt gcgtacggga tatctcagtc
    27001 ttactcaatt attttgaaat caatcgtggt cgcgatgctg gaccactcca tcaccgtttt
    27061 tacacaacag ccagtagcca aagttttgca caaattggtg aagaatggct ggaaaaagag
    27121 attcatgtgg agcatgtaga attatgacaa ataaaattta tgaatataag gatgaccagg
    27181 actggtatgt tgggtcttat agtatttttg gtggcgttaa cagtttgagc gactataaga
    27241 cagattttcc tctgtttgaa ttctccaaaa tatttggaga tgaagagtat ggtttcccgc
    27301 tttcagttac tgttttacgc tatggttcta cctaccgttt gttctccttt gtggtagaca
    27361 tgcttaatca agaaatggga cgaaacttgg aagttattca acgtcatggg gccctgctct
    27421 tggttgaaaa tgggcaactc ttgtatgtag aattgcctaa agaaggggtc aatgttcatg
    27481 atttctttga gacaagcaag gtcagagaaa ccttgttgat tgcgactcgt aacgaaggta
    27541 aaaccaagga attccgagct atctttgata agttaggcta cgatgtggaa aatcttaatg
    27601 actaccctga cctgcctgaa gtagcagaaa caggtatgac ctttgaagaa aatgcccgcc
    27661 ttaaggcaga aaccatttct caattaacgg gcaagatggt tttggcagat gattctggtc
    27721 tcaaagtcga tgtccttggt ggcttaccag gcgtctggtc agctcgtttc gcaggtgtgg
    27781 gagcaactga ccgtgaaaat aatgccaaac tcttgcacga attggccatg gtctttgaac
    27841 tcaaggaccg ctcggctcag ttccacacaa ccctagtcgt agccagccca aataaggaaa
    27901 gtttagttgt tgaagcagac tggtcaggtt atattaactt tgaacctaag ggtgaaaatg
    27961 gctttggcta tgatcccctc ttccttgtag gagagacagg tgagtcatca gctgaattaa
    28021 ccctggaaga aaaaaatagt caatctcacc gtgccttagc cgttaagaaa cttttggagg
    28081 tatttccatc atggcaaagc aaaccatcat tgtaatgagc gattcccatg gcgatagctt
    28141 gattgtggaa gaagtccgtg atcgctatgt gggcaaagtc gatgccgttt ttcataacgg
    28201 cgattctgaa ctacgtccgg attctccact ttgggagggc atccgcgttg ttaaagggaa
    28261 catggacttc tacgccggct acccagaacg tctggtgact gagcttggtt cgaccaagat
    28321 tatccaaact catggtcact tgtttgacat caatttcaac tttcaaaagt tggactactg
    28381 ggctcaggag gaagaggccg ctatctgcct ctatggtcac ttgcatgtgc caagtgcttg
    28441 gatggaaggc aagatcctct ttctaaatcc aggttctatc agccaaccac gaggtaccat
    28501 cagagaatgt ctctatgctc gtgtggagat tgatgatagt tacttcaaag tggacttttt
    28561 gacacgagat cacgaggtgt atccaggttt gtccaaggag tttagccgat gattgccaag
    28621 gagtttgaga ctttcttgtt ggggcaggag gaaacttttt tgacccctgc taaaaatcta
    28681 gctgtgttga ttgataccca caatgcggat catgcgaccc tcttgcttag tcagatgacc
    28741 tatacccgtg ttcccgttgt gacagatgaa aaacagtttg ttgggacgat tggactcaga
    28801 gatattatgg cttatcagat ggagcatgac ttgagccaag aaatcatggc ggatacggat
    28861 atcgttcata tgacaaaaac ggacgtagcg gttgtttcgc ctgatttcac cattacggag
    28921 gtcttgcaca agctagtaga tgagtccttc ttaccggttg tggatacaga gggtattttc
    28981 caagggatta ttacgcgcaa gtccatcctc aaggccgtta atgccctctt gcatgatttt
    29041 agtaaggaat atgagattcg atgccaatga gagacagaat ttcagccttt ttagaggaaa
    29101 agcagggctt gtctgtcaat tccaagcagt cctataagta tgatttggag caatttttag
    29161 acatggtagg tgagcggatt tctgagacca gtctcaagat ttaccaagcc cagctagcca
    29221 atctaaaaat cagcgcccag aagcgaaaga tttcggcctg taaccaattt ctatactttc
    29281 tctatcaaaa aggagaggtg gacagctttt accgcttgga attagccaaa caagctgaaa
    29341 agaagacgga aaagccagag attctatacc tagactcttt ttggcaggaa agcgaccatc
    29401 cagagggccg cttgctagcg ctcttaatcc tagaaatggg gctcttgccc agtgagattt
    29461 tagccatcaa ggttgcggac atcaatctgg attttcaggt gttgcgaatc agcaaggctt
    29521 cccaacagag gattgtcacc attcccacgg ccttgctttc agaattggaa cccttgatgg
    29581 ggcagaccta tctttttgaa agaggagaga aaccctattc tcgtcagtgg gcctttcgtc
    29641 agttagaatc ttttgtcaag gagaaaggtt ttccatcctt atcagctcaa gtcttacgtg
    29701 aacagtttat tctaagacaa atagaaaaca aggtcgattt gtacgaaatt gcaaaaaaat
    29761 taggattaaa aacagtcctg accttagaaa aatatagata atggatatta aattaaaaga
    29821 ttttgaagga cccctggact tgctcttgca tctggtttct aagtaccaga tggatatcta
    29881 cgatgtgccc attacggaag tcatcgaaca gtatctagcc tatgtctcaa ccctgcaggc
    29941 catgcgtctg gaagtgacgg gtgagtacat ggtcatggct agtcagctca tgctgattaa
    30001 gagtcgtaaa ctccttccga aggtagcaga agtgacagac ttgggggatg acctggagca
    30061 ggacctcctc tctcaaatcg aagaatatcg caagttcaag ctcttgggtg agcacttgga
    30121 agccaagcac caagaacgag cccagtatta ttccaaagcg ccgacagagt tgatttacga
    30181 agatgcggag cttgtgcatg acaagacgac cattgacctc tttttggctt tttcaaatat
    30241 cctagccaag aaaaaagagg agtttgcaca aaatcacacg actatctttc gggatgagta
    30301 taagattgag gacatgatga ttattgtgaa agaatccttg attggacgag atcaattgcg
    30361 cttgcaggat ttgttcaagg aagcccagaa tgtccaagag gtcatcaccc tctttttggc
    30421 aaccctagag ttaatcaaaa cccaggagct gatcctcgtg caagaggaga gtttcggaga
    30481 tatctatctc atggaaaaga aggaagaaag tcaagtgcct caaagctaga cttgatagag
    30541 aggaaagatg agtactttag caaaaataga agcgctcttg tttgtagcgg gtgaagatgg
    30601 gattcgggtc cgccagttag ctgaactcct ctctctgcca ccgacaggca tccagcagag
    30661 tttaggaaaa ttagcccaga agtatgaaaa ggacccagat tccagtttgg ctttgattga
    30721 gacaagtggt gcttatagat tggtgaccaa gcctcaattt gcagagattt tgaaggaata
    30781 ctctaaggcg cctatcaacc agagcttgtc tcgggctgcc cttgagacct tgtccattat
    30841 tgcctacaaa cagccgatta cgcggataga aattgatgcc atccgtgggg ttaactcgag
    30901 tggagccttg gcaaagttgc aagctttgga cctgataaag gaagacggga aaaaggaagt
    30961 attggggcgc cccaacctct atgtgactac ggattatttc ctagattaca tggggataaa
    31021 ccatttagaa gaattaccag tgattgatga gcttgagatt caagcccaag aaagccaatt
    31081 atttggtgaa aggatagaag aagatgagaa tcaataagta tattgcccac gcaggtgtgg
    31141 ccagtaggag aaaagcagaa gagctgatca agcaaggttt ggtgacagtt aacggccaag
    31201 tggtgcgtga actagcaacc actatcaagt caggcgacaa ggtcgaagtt gaaggtcaac
    31261 ctatctacaa cgaagaaaag gtctattatc tgcttaacaa accacgcggt gtcatttcca
    31321 gtgtaacaga tgacaagggt cgcaagacgg ttgtcgacct cttgcccaat gtcaaagagc
    31381 gcatttaccc tgtgggtcgt ttggactggg atacatcagg agtcttgatt ttgaccaatg
    31441 atggggactt tacagacgag atgattcacc ctcgtaatga gattgacaag gtttatgtcg
    31501 cgcgtgttaa aggtgtggcc aataaggaca atcttcgccc cttgacccgt ggtcttgaga
    31561 ttgatggtaa gaaaaccaag ccagctgttt atgaaattct caaagtggac ccagtcaaaa
    31621 atcgctctgt ggtgcagttg accatccatg aagggcgtaa ccatcaggtt aaaaagatgt
    31681 ttgaagctgt tggtctccaa gtagataagt tgtctcggac tcgtttcgga cacctagact
    31741 tgacaggact ccgtccagga gaatcccgtc gtcttaataa aaaagaaatc agccaactac
    31801 acaccatggc tgtaactaag aaataatgaa acgaatttta atagcgcttg tgcgctttta
    31861 ccaacgtttt atctcaccag tctttccacc ctcttgtcgc tttgagctga cttgttccaa
    31921 ctatatgatt caggctattg aaaaacatgg ttttaagggg gtattgatgg gcttggctcg
    31981 gattttacgt tgtcatccct ggtcgaaaac aggtaaggac cccgttccag accacttttc
    32041 ccttaaacga aatcaagaag gggaatgagg tggggtaaat agatttcaaa atgataaaaa
    32101 cgcatcctat caggtttgag tgaacttgat aggatgcgtt ttagaatgtc aaaattttat
    32161 actcttcgaa aatctcttca aaccgcatca gctttcatct gcaacctcaa aacagtgttt
    32221 tgagcaacct gcggctagtt tcctagtttg ctctttgatt ttcattgagt attaaattga
    32281 gtttgaagtg gcttatttca aagctttttg tatgtcttca atcatgagtt ttgttgattc
    32341 aagtccgcct ccgcttagat accagaggtc tggtgttagt tggataatct taccattttt
    32401 agcagcaggt gtttcagcga taagggcatt ttctaggaca ccgtcgttgc tagagttgtc
    32461 cccaccgatg gcaagggtac ggttgatgac aaagaggatg tcagggttga tttctttgac
    32521 actttcaaag ctgacttctt gtccgtggcg tgagtcttca aattttgtat cagttggttt
    32581 gaatttcaag gtttggtaca agaaagagaa acgagatttg gcaccaaagg ctgccatttt
    32641 tccttcatta aggaggatcg caagggcttt tttgtcagag ctttcatttt tagtagcgac
    32701 ttcttggatg ctcttgtcta gcttggccaa ttcttccttg gctttttgtg tactagtttc
    32761 gccgaaggca cttgctaagg attcgatatt agccttggta gaagtccagt agtcatcctt
    32821 gcttgcttgg aagagaacgg ttggggcgat ttctttgaat ttgtctacaa atttttgtgt
    32881 acgtggtgaa gcgataatca aatcaggctc aagggcggcg atagcttcta aatcaggttc
    32941 tttcatagaa ccaacatttt tgacagttcc cactaggtct tttagataag tcggaacagt
    33001 ttttgtaggc attccgacga tatttttttc aaatcctaaa gcgcgaatag tatccgcagc
    33061 gccgaggtca aaggtcacaa tcttttcagg aactttggaa agtttgacct cgtccagtga
    33121 acttttaatg gttacctctg ttggagcaga gctactggtc tctgtctgac tagtgcttga
    33181 gtttgtacta catgcaccaa gtaggagcaa gaaactggcc actagggcag tgaaataaag
    33241 tttaagggat gttttcataa tttctccttt ttaaaatgtg ataacgattt agggagtctc
    33301 ttaatcttat tgactaagag actgaaggtt ctctaacttg agcttttatg ttactagcta
    33361 tagatacaga tctttttgtc attgatatca gctagcgtga tgggaatctc ataaagttga
    33421 ctgagtaggt cagcctgcat gatttgatcg gttcttccct tgctaaagac ctggccgtcc
    33481 ttgaaggcga caatttcatc tgcatactga ctggccatgt tgatatcgtg gaggacgatg
    33541 ataatggtct tgccgagttc ctccaccagt cgtcgaagaa tctgcatcat gctgacgctt
    33601 tgcttgatat cgagattgtt gagtggttcg tccagcaaga taaagtccgt atcctgggcc
    33661 agtaccatag cgataaagac gcgctggagt tgcccccctg acaggctatt gatgtagcgg
    33721 tcttttaagt tggtcagttc caaatagttc agagtttctc ggattttttc ccagtcttct
    33781 gatctaagtc gacctcggct gtagggaaaa cgtccaaaac tgaccagttc ttcaacagtc
    33841 aatttggctt ggtaattgat tttctgtttt aggatggtta gttcttgggc cagttcttgc
    33901 gaattccagc tctcgatttc acgtcctttg atactgagaa ctccctgatc tttcttggtt
    33961 agtctgctca tgatggagag gagagtcgat tttccagcac catttggacc aataaaggct
    34021 gtcagttttt gaggactgac ttcaagcgaa atgccttgca aaatatcctg tttttgaatg
    34081 gatttgtcaa tgttttccag tttcactgac gagacctcct atatagtaag ataaagaata
    34141 agaagccacc cacactctca atgatcatac tgatacgaat ttccagtgca aagactcgtt
    34201 caatcaaggc ttgccccaag gttaagctaa taaatccaac cagaatggcc actataaaga
    34261 gtaacttgtg ctgatagtct ttgacaatca ggtaggtgag gttggccagc ataaagccga
    34321 agaaggccat aggtcctacc aaggcagtgg ccgttgaggt caaaagcacg attccccaga
    34381 ggagctcttt ctgttctttt tcaacatcga gtcccaatat ctgagccgtt tctctttgca
    34441 ggtgcaagac atctagaacg actgcttttc gaaagaaaaa gattgtcaaa gcgaggatga
    34501 tcagagaacc gatggctagg atggaagtgt tgagatgttg aaaggaggca aaaagactat
    34561 tttgcagttt atcgtattcg tttggatcca ttaggacttg aaggaaggtg ctgatatttc
    34621 gaaagagact tctgagcgct agacagatca gcaggatgaa gaccaggtct tgcttcatca
    34681 gtgtcttcaa gtaaccttgt aaggcgagaa agaagaggga ctggacaaga agtaagacta
    34741 ggaattctaa gataggggat ttgccaagtt gaagaaactt gctttcaaaa accagtagta
    34801 gggtttgtag taggacgtag aaggattcaa ttcccaaaat actaggcgtc aggaagcgat
    34861 tttccgtcag ggtttgaaaa ctaatggtcg aaatcccagt cgcgatggct accaagagat
    34921 aaacgatgat cttttgggaa cgcaacttcc aagcaaaggc tgacaagtga gtgatgggcc
    34981 aaaagtagag aagacaagct ccgatggcaa gaataatgag aatccagaag agcttggtat
    35041 gtttgctttt agtctgcatc ttttcgtccc cctctccaga gaagtagtat aaagacgaga
    35101 ctaccgatga ttcctagcaa gagactgaca gacaactcat agggcctaat cagaactcgg
    35161 gataggatat cgcaagccag aactagattg gcaccaacca gtgcgaccat gagtttggtt
    35221 tgacttagat tatctccata gcgcttgcga acaagattgg gaacgataac tccgagaaat
    35281 ggtaggccac ccacggtaat catggtgacg cttgtcgtta gcgccaccag aaagagggcc
    35341 agtttttcaa gtagggagta ggaaatcccc aaactctcgc tggtttcttt ccctagattc
    35401 atgatggtga aggtttggga taatttccaa acggttatca ggatgatgag gcctaagaag
    35461 agccactcat actgatgggt ctgaatcatg gagaaggagc cctgggtcca ggcagtcata
    35521 ctctgaacca gattgaaacg ataggcgata acttctgtga ctgagccgat aatcccgcta
    35581 tagatgatcc caatcagagg caacatccac ctttccttta cagtaaaaat ggtcataaag
    35641 gctaggaaga agagggtgaa tacgatggat gaaacaaaag cgaagagcat cttttgggtc
    35701 agactagccg atggaaagac aaagagactc agcaccattc ccagtttggc ggcttcagtc
    35761 gttccaactg tactcggtgc agcaaactga ttttgggtaa tagtctgcat gagaaggcct
    35821 gccatactca tactagaggc agtcaggaga atactgatag ttcttgggag acgggactct
    35881 tgaaagagga gccaggtctg ctggtcgaaa tcaaatagct ttccccatga aaaatcactg
    35941 gtcccaatac taatagagag aaagactagg agtagaagta agccaattaa ataatgagaa
    36001 agtttcatac cccgtccttt catgtagatt tggtatcgaa agatacctgc ggatataaat
    36061 gtaacattat ttttctaatc tgtcaataaa atttctgaca atttaataaa tacaacaagg
    36121 agagagcaac aagactttct cctttgttat cctattctaa aatgttttta ccttaatctg
    36181 ataaaataat atcttcgagg gagtagctag ccgtccaatc aagatattgt ttagcttttg
    36241 aagcatctgc taggacactg gctgggtcac tagcacgtcg agcaacaatc tcgtgtggga
    36301 ttttttaatt tagtaattct tcagcagttt taaagatttc tttgatagta tagccttttt
    36361 tagttcctaa gttaaagatt tgagaagaac tgtcttcttg aaataggtag ttcattcctt
    36421 taacatgagc ctatacaagg tccaagacat aaatgtaatc tcgaatacat gaaccgtcac
    36481 gtgtatcgta gtcatctcca aatattttta agctatcatt ttgtcccaat gcggtcttgt
    36541 tgatatttgg aatgatgtga gttggatttt tcacacgcag accgtttgaa gcatccattt
    36601 cagccccagc aacattaaag taacggaaaa taacatattt ccagtcgtag cgattggcca
    36661 tccagtaaat cattcgttcg cccatcagtt ttgtctctgc ataagggttg acagggtcga
    36721 gcagggtatc ttcagtcacc ggcttgtcaa tacagttatt tccatagaga gaagcagtcg
    36781 aagagaacat gattttttga atgccaactt cagataagac tttgagaact tggttcatac
    36841 cagcaacgtt ggcagtgaag tatttacttg gattttcaat actttcgctc acaacaattt
    36901 cacctgcaca atggaggaca gcatcaatct gattttcttc taagtaagcc tttaaggcgc
    36961 tagcatcata aacatccagt tctttaaagc tagcacgact atccacagcc gctcgatttc
    37021 ctgtggagag attatcgagg acatgcacct gatagccagc atttaaaaga gctttaacgg
    37081 tatgggagcc aatgtagcca gtctcacctg taacaagaat tgttttggtc ataatttttt
    37141 ccttttctag ttttgtacta tagtaaattg aaataagata tgaacaactc tattaggaaa
    37201 gtcaaattaa tttctagaaa tgttttagca gctacagcgt actattccaa actcaaccaa
    37261 ctatatattt aaagaaagaa gaaagggaag tcaactattt tctgtaaatt ttatgaaaaa
    37321 tccaaacaac tttgatggtg tattgttttt ttgtttggaa ataaatattc gagttaattt
    37381 tggaatgttt actagatttt gcactacatg caagagaata ctatcctttt ctaagataga
    37441 gcaggactaa gatactaact tagaaatcca ccttcccact atccttctcc tataaaaagt
    37501 ggtaaaatgg atgaaagaaa gaaggaactg aaatgacaac attattttca aaaattaaag
    37561 aagtaacaga acttgctgca gtctcaggtc atgaagcgcc tgtccgtgct tatcttcgtg
    37621 aaaagttgac accgcatgtg gatgaagtgg tgacagatgg cttgggtggt atttttggta
    37681 tcaaacattc agaagctgtg gatgcaccgc gcgtcttggt cgcttctcat atggacgaag
    37741 ttggttttat ggtcagcgaa atcaagccag atggtacctt ccgtgtcgta gaaatcggtg
    37801 gctggaaccc catggtagtt agcagccaac gtttcaaact cttgactcgt gatggtcatg
    37861 aaattcctgt gatttcaggt tctgttcctc cgcatttgac tcgtggaaag gggggaccaa
    37921 ccatgccagc cattgccgat atcgtttttg atggtggttt tgcggacaag gctgaggcag
    37981 aaagttttgg catccgtcct ggtgatacca tcgtaccaga tagttctgca attttgacag
    38041 ccaatgaaaa aaatatcatc tcaaaagctt gggataaccg ctacggtgtc ctcatggtaa
    38101 gcgagctagc tgaagcttta tcaggtcaaa aactcggcaa tgaactctat ctgggttcta
    38161 acgtccaaga agaagttggt ctgcgtggcg ctcatacctc tacaaccaag tttgacccag
    38221 aagtcttcct cgcagttgat tgctcaccag caggtgatgt ctacggtggt caaggcaaga
    38281 ttggagatgg aaccttgatt cgtttctatg atccaggtca cttgcttctt ccagggatga
    38341 aggatttcct tttgacaacg gctgaagaag ctggtatcaa gtaccaatac tactgtggta
    38401 aaggcggaac agatgcaggt gcagctcatc tgaaaaatgg tggtgtccca tcaacaacta
    38461 tcggtgtctg cgctcgttat atccattctc accaaaccct ctatgcaatg gatgacttcc
    38521 tagaagcgca agctttctta caagccttgg tgaagaaatt ggatcgttca acggttgatt
    38581 tgattaaaca ttattaaacc ataagggagg tggtagggat ggtagaacca aacctagaaa
    38641 gccttataaa agatctttac aatcatgctc gacatgattt gagtgaagat ttagttgctg
    38701 ctctcctaga gactgctaaa aaactgccta ctacaaatga gcaattgcag gcagttcgtc
    38761 tctcaggcct ggtcaatcgt gaattgctcc taaatcccaa acatccagca cctgagttgc
    38821 tcaacttggc tcgctttatc aaaagagaag aagccaagta cagaggaact gcgacttctg
    38881 cgcttatgta tgaggaactc tttaaaatgc tttgattcca ttgtggatca aagcattttt
    38941 tgtaagacct atctcgtgag cgttcaaata gtagtaacaa ggaatcatga gaagtcagcc
    39001 gagaccatag tagtgaagaa acttctgtaa tggaagtgga gcgaagtgag gaatcgtcaa
    39061 acggtagggg ataggctgtt tgaagggtgc tacgaaaaag atagggcaag gtgaaattat
    39121 agcgggatga aataagatat gaacaaattg attaggaaaa tcaaatgaat ttatagaaat
    39181 cttttagcag tcatggtgtc ctattccagt ttcgaaatgc tataaatacg aacaaattga
    39241 ttgggaaatt caaatcgctt tctatcaatg ttttagaaga tacagtgccc tagtccaact
    39301 tcaatatact ataaaagaac agatggaagc aattatgatt tacttctatc tttaaaataa
    39361 atggtctgat aggaaaaatg tgtcccctca taaaaaatag gatagtacgg atggaaggct
    39421 tttgtagact ggaggacgaa ggagtttaga aactctcgtt aaaagttagt tgagccggag
    39481 tatggtggtg tggataatta tcaaaaatta tttccaaatc gaaatagttg acagttagaa
    39541 cgatgagtgt tacaattatt ttattcattt cgatatcgaa ataaattgga ggtgttatga
    39601 aagatagtca tttgctagcc catcatattc gtttgttgaa tgggcggatt tttcaaaagt
    39661 tactgagtca agatcctgag gctctttata ggggtgaaca gggcaagatt ttagcggttt
    39721 tatggaatag tgaaactggc tgcgcaactg cgacagatat cgcgcttgcg actgggcttg
    39781 cgaataatac gctgacgact atgataaaaa agctagagga acaaaagctt gtaattgtta
    39841 gtccgtgtgg aaaagacaag cgtaagaagt atttagtttt aacggagtta ggcaagttcc
    39901 agaaagaagt ggggcatcgt gtcagtcaga aattggatac tatcttttac aaaggatttt
    39961 cagaggaaga aattcaccaa tttgaaggtt ttcaagaaag aattttggcg aatttgaaag
    40021 agaagggaaa tgaggtttag aatatgtcac aacaagtgaa aaatgctcac aacctataca
    40081 tccatgccat tcaagacgga cgagttgctg aggctcaagc ccagtctgta ggggatacct
    40141 atatccaaca ttcgacaggt gttcctgacg ggaaagaagg atttgcagcc ttctttgcag
    40201 atttctttga gcgtcatcca gagcgtcaga ttaagattgt ccgcaccatt gaggatggca
    40261 atctggtctt tgttcatgtt catcaatatc tgaatggtgg agaagctcaa tgggtgacga
    40321 cggatacttt ccgtgcggat gagaatggtt gtattgttga gcattgggat gtcattgact
    40381 actatcgaac acctgaaaat gaccaactag atcaaatttt tggagatttt gaaatcaagg
    40441 atttggataa gaaagcagaa aataaaaagc tggttcgccg tttcttgaca gaaattttcc
    40501 aaaatgggga gctagagcag tggagtgatt atgtggcaga cgatttgatt cagcataatc
    40561 atgagattgg acaaggaagt gctgcttata aaaactatgt ggctgaatat agtgtcactt
    40621 ttgactttgt tttccaactc ttaggacaag gaaactatgt ggttagctat ggtcagactc
    40681 agattgatgg cgttgcttat gcccagtacg atatcttccg tttagagaac gggaaaattg
    40741 tggagcattg ggataataag gaagtcatgc ctaaggtaga agacttgacc aatcgaggga
    40801 agttttaaat tgaggacaaa gaatgattga atacaaaaat gtagcactgc gctacacaga
    40861 aaaggatgtc ttgagagatg tcaacttaca gattgaggat ggggaattta tggttttagt
    40921 agggccttct gggtcaggta agacgaccat gctcaagatg attaaccgtc ttttggaacc
    40981 aactgatgga aatatttata tggatgggaa gcgcatcaaa gactatgatg agcgtgaact
    41041 tcgtctttct actggttatg ttttacaggc tattgctctt tttccaaatc taacagttgc
    41101 ggaaaatatt gctctcattc ctgaaatgaa ggggtggagc aaggaagaaa ttacgaagaa
    41161 aacagaagag cttttggcta aggttggttt accagtagcc gagtatgggc atcgcttacc
    41221 tagtgaatta tctggtggag aacagcaacg ggtcggtatt gtccgagcta tgattggtca
    41281 gcccaagatt ttcctcatgg atgaaccctt ttcggccttg gatgctattt cgagaaaaca
    41341 gttgcaggtt ctgacaaaag aattgcataa agagtttggg atgacaacga tttttgtaac
    41401 ccatgatacg gatgaagcct tgaagttggc ggaccgtatt gctgtcttgc aggatggaga
    41461 aattcgccag gtagcgaatc ccgagacaat tttaaaagcg cctgcaacag actttgtagc
    41521 agacttgttt ggaggtagtg ttcatgacta atttaattgc aacttttcag gatcgtttta
    41581 gtgattggtt gacagctcta tctcaacatt tgcagttgtc acttttgacc ttgttactag
    41641 ctattttgct tgcgattccc ttggctgttt ttcttcgcta tcatgagaag ctggccgact
    41701 gggtcttgca gattgcaggt attttccaga ccatcccgtc tctggccttg ttggggctct
    41761 ttatcccttt gatgggaatt gggaccttgc cggctttgac agctctagtg atttatgcga
    41821 ttttccctat tttgcaaaat actatcactg ggctgaaggg aattgatccg aacctgcaag
    41881 aggctgggat tgcctttggg atgaccagat gggaacgtct caagaaattt gaaattccac
    41941 ttgccatgcc tgttatcatg tctgggattc ggacggcagc tgttttgatt atcggtacgg
    42001 caaccttggc ggccttgatt ggagcagggg gactgggttc ctttatcctg ttgggaattg
    42061 accgtaataa tgccagtttg attttgattg gggcactttc ttctgcagtg cttgctattg
    42121 cctttaactt cctactaaaa gtaatggaaa aagcaaaatt acggacgatt ttctcaggtt
    42181 ttgccttggt gacggtattg ctgagtctat cttatagtcc agccctcttg gttcaaaaag
    42241 agaaagaaaa cgtgattatt gcagggaaaa ttggtccaga accagaaatt ttggctaata
    42301 tgtataaact tttaatagaa gaaaatacaa gtctaacagc aaccgttaag cctaactttg
    42361 ggaaaacaac tttcctttat gaagcgttga aaagcggaga cattgatatc tatcctgaat
    42421 ttactggtac ggtgactgaa agtttgcttc aaccatcacc taaagtgagt catgagccag
    42481 agcaggttta tcaggtggcg cgtgatggca ttgccaaaca ggatcatcta gcctatctta
    42541 aacccatgtc ttatcaaaat acttatgctg tagctgttcc gaaaaagatt gcgcaagaat
    42601 atggcttgaa gaccatttcg gatttgaaaa aagtggaagg tcagttgaag gcaggcttta
    42661 cactcgagtt taacgaccgt gaagatggaa ataagggctt gcaatcaatg tatggtctca
    42721 atctcaatgt ttcaaccttg gaacctgctc ttcgctatca agcgattcag tcaggtgaaa
    42781 ttcaaattac agatgcctat tcgactgatg cggaattgga gcgttatgat ttacaggtct
    42841 tggaagatga caagcaactc ttcccacctt atcagggggc gccactcatg aaagaagctc
    42901 ttctcaagaa acacccagag ttggaaactg ttcttaataa attggctggt aagattacag
    42961 aaagccagat gagccagctt aactatcaag ttggtgtcga aggcaagcca gcagaacaag
    43021 tagccaagga atttctacaa gaacaaggtt tgttgaagaa ataaaaggag aggaatgtca
    43081 gaggtagcca ctttcttccc tagacaaaag agcctgggac aatagtctct tatctccaaa
    43141 aaaagcaacg gatttgccgt tgcttttttt gcatggttac gatagtcttg gtaaaataga
    43201 attgcttaat aaaccattta aaaag
//
LOCUS       DAVHBD010000016        42305 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000016 DAVHBD010000000
VERSION     DAVHBD010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.016"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VVK04_000871"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VVK04_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU3989547.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VVK04_000872"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VVK04_000872"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU3989548.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VVK04_000873"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VVK04_000873"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU3989549.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKFKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VVK04_000874"
     CDS             complement(3790..5058)
                     /locus_tag="VVK04_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU3989550.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VVK04_000875"
     CDS             complement(5178..5546)
                     /locus_tag="VVK04_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU3989551.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VVK04_000876"
     CDS             complement(5539..5805)
                     /locus_tag="VVK04_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU3989552.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VVK04_000877"
     CDS             complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VVK04_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU3989553.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKEIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRIKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9373..9942)
                     /locus_tag="VVK04_000878"
     CDS             complement(9373..9942)
                     /locus_tag="VVK04_000878"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU3989554.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VVK04_000879"
     CDS             complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VVK04_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU3989555.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11212..11406)
                     /locus_tag="VVK04_000880"
     CDS             complement(11212..11406)
                     /locus_tag="VVK04_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU3989556.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11471..12607)
                     /gene="dnaN"
                     /locus_tag="VVK04_000881"
     CDS             complement(11471..12607)
                     /gene="dnaN"
                     /locus_tag="VVK04_000881"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU3989557.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12766..14127)
                     /gene="dnaA"
                     /locus_tag="VVK04_000882"
     CDS             complement(12766..14127)
                     /gene="dnaA"
                     /locus_tag="VVK04_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU3989558.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENIATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14341..15099)
                     /locus_tag="VVK04_000883"
     CDS             complement(14341..15099)
                     /locus_tag="VVK04_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU3989559.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15157..16338)
                     /locus_tag="VVK04_000884"
     CDS             complement(15157..16338)
                     /locus_tag="VVK04_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU3989560.1"
                     /translation="MKHIKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16521..17000
                     /gene="rlmH"
                     /locus_tag="VVK04_000885"
     CDS             16521..17000
                     /gene="rlmH"
                     /locus_tag="VVK04_000885"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU3989561.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17044..17117
                     /locus_tag="VVK04_000886"
     tRNA            17044..17117
                     /locus_tag="VVK04_000886"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17078..17080,aa:Arg,seq:tct)
     gene            17282..17407
                     /gene="comC"
                     /locus_tag="VVK04_000887"
     CDS             17282..17407
                     /gene="comC"
                     /locus_tag="VVK04_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU3989562.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17428..18729
                     /locus_tag="VVK04_000888"
     CDS             17428..18729
                     /locus_tag="VVK04_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU3989563.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDRIYNEVLVKANHKL
                     RSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIELLDLVRIM
                     SVLLNNAVEGSADSYKKQMEVAVIKMETETVMVIQNSCKMTMTPSGDLFALGFSTKGR
                     NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18726..19478
                     /locus_tag="VVK04_000889"
     CDS             18726..19478
                     /locus_tag="VVK04_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3989564.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENYEVNQLYFLDIDIHGIEKKGFEVAQFIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19530..19601
                     /locus_tag="VVK04_000890"
     tRNA            19530..19601
                     /locus_tag="VVK04_000890"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19563..19565,aa:Glu,seq:ttc)
     gene            19607..19680
                     /locus_tag="VVK04_000891"
     tRNA            19607..19680
                     /locus_tag="VVK04_000891"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19641..19643,aa:Asn,seq:gtt)
     gene            complement(19721..20263)
                     /locus_tag="VVK04_000892"
     CDS             complement(19721..20263)
                     /locus_tag="VVK04_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU3989565.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFKYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20442..21128
                     /locus_tag="VVK04_000893"
     CDS             20442..21128
                     /locus_tag="VVK04_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU3989566.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKMPP"
     gene            21125..21208
                     /locus_tag="VVK04_000894"
     CDS             21125..21208
                     /locus_tag="VVK04_000894"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989567.1"
                     /translation="MTDSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21293..21631
                     /locus_tag="VVK04_000895"
     CDS             21293..21631
                     /locus_tag="VVK04_000895"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989568.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            21659..21973
                     /locus_tag="VVK04_000896"
     CDS             21659..21973
                     /locus_tag="VVK04_000896"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU3989569.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22074..24626)
                     /locus_tag="VVK04_000897"
     CDS             complement(22074..24626)
                     /locus_tag="VVK04_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU3989570.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYIIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24688..26310)
                     /locus_tag="VVK04_000898"
     CDS             complement(24688..26310)
                     /locus_tag="VVK04_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3989571.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26516..27541
                     /gene="trpS"
                     /locus_tag="VVK04_000899"
     CDS             26516..27541
                     /gene="trpS"
                     /locus_tag="VVK04_000899"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU3989572.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27693..29171
                     /gene="guaB"
                     /locus_tag="VVK04_000900"
     CDS             27693..29171
                     /gene="guaB"
                     /locus_tag="VVK04_000900"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU3989573.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29221..30318)
                     /gene="recF"
                     /locus_tag="VVK04_000901"
     CDS             complement(29221..30318)
                     /gene="recF"
                     /locus_tag="VVK04_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU3989574.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSVQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNTTDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30321..30689)
                     /gene="yaaA"
                     /locus_tag="VVK04_000902"
     CDS             complement(30321..30689)
                     /gene="yaaA"
                     /locus_tag="VVK04_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU3989575.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30848..32098
                     /locus_tag="VVK04_000903"
     CDS             30848..32098
                     /locus_tag="VVK04_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU3989576.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32095..33378
                     /locus_tag="VVK04_000904"
     CDS             32095..33378
                     /locus_tag="VVK04_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU3989577.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33420..34241
                     /locus_tag="VVK04_000905"
     CDS             33420..34241
                     /locus_tag="VVK04_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU3989578.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34252..34797
                     /gene="pgsA"
                     /locus_tag="VVK04_000906"
     CDS             34252..34797
                     /gene="pgsA"
                     /locus_tag="VVK04_000906"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU3989579.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34794..35621
                     /locus_tag="VVK04_000907"
     CDS             34794..35621
                     /locus_tag="VVK04_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU3989580.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRKIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPD
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYNLPENYLTESELEDKLWELL"
     gene            35606..36445
                     /locus_tag="VVK04_000908"
     CDS             35606..36445
                     /locus_tag="VVK04_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU3989581.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36438..37232
                     /locus_tag="VVK04_000909"
     CDS             36438..37232
                     /locus_tag="VVK04_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU3989582.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37291..38109
                     /gene="mreC"
                     /locus_tag="VVK04_000910"
     CDS             37291..38109
                     /gene="mreC"
                     /locus_tag="VVK04_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU3989583.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFYSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38109..38603
                     /gene="mreD"
                     /locus_tag="VVK04_000911"
     CDS             38109..38603
                     /gene="mreD"
                     /locus_tag="VVK04_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU3989584.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38697..39875
                     /locus_tag="VVK04_000912"
     CDS             38697..39875
                     /locus_tag="VVK04_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU3989585.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40099..40878
                     /gene="rpsB"
                     /locus_tag="VVK04_000913"
     CDS             40099..40878
                     /gene="rpsB"
                     /locus_tag="VVK04_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU3989586.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40957..41997
                     /locus_tag="VVK04_000914"
     CDS             40957..41997
                     /locus_tag="VVK04_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU3989587.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT        13269 a         7284 c         7791 g        13961 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggat tctgtgcacc aaacatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagttttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcttcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 tttctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca tagtctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt tttaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattaatt caccttctaa tggaagtcca aaagaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tccttttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt taaattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatc ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccaatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agaatttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcataaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcatgacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagctag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacataga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat cttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagataag agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catacttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaattc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aatttcccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccagc ttttcatctg acaaactcaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttat agaagaaaaa tatcaaatgg aattttcttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcaaacctt ctaaaatttc
     5941 ataatctttc ttattttgga catcaaatac aagctccatt aatcccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacagtcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttgaccaa accaatctct aacagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttga ttcttgtgtt
     6361 agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg aatacaattc
     6421 aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc ctgctccacg
     6481 aatcgaaaga tctcgcattg caatcttaaa gccagagccc aattctgtaa atcctttaat
     6541 cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat acatgagata
     6601 agcataagca atacgattac tacgaccgac tcttcctctt aactgatata aggttgacaa
     6661 gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt ccacccctgt
     6721 ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt ctaatagagt
     6781 attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag cctccggaat
     6841 caactcctgt aattctgaaa ccttctgaac aattgtgtca actttgttgt aaagatagta
     6901 aacttgacct ccacgctcca tttcacgcaa gacagcatca cgaatgacac tatcattctt
     6961 ttccaaaaca taggtctgaa cagggtagcg attagtcggc ggagtttcaa taacagacaa
     7021 atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag cggtcaaggt
     7081 taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga caccaaatcg
     7141 ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt ttgacaaaac
     7201 acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa gtgttgcagt
     7261 ctgctctttt ttacttctaa agcgactcaa cacatcaaca ttaactgcaa aattttggaa
     7321 tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa ctagaatgac
     7381 aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt cagtctttcc
     7441 aaaaccaaca tccccaacta aaagtcgatc cattggctga gaagcctgca tatccctctt
     7501 gatttcctca atactacgaa gttgatcatc cgtttcaaca taagggaaag catcatcaaa
     7561 ggcatcttga tcatcatcat cagctgagaa agcaaaaccc ttcaactgac tacgttcaga
     7621 gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct tttgcttggc
     7681 ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat cacttgaaat
     7741 atatttggac agtagatgaa tctgttccac gggaatagaa atttgatcac cattttggta
     7801 ctggacactg acataatcac gatgaatttc cttgatttca atggtttcaa ttcctagata
     7861 ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt cattgtaatc
     7921 ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta atttcttttg
     7981 aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa aaccatgtct
     8041 gagattaccc tctattaaat ttacagattc tttacagata cttgtcttat ctctagaatc
     8101 caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca ttgaattgct
     8161 agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt cttttagaaa
     8221 agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa ttttgtcaaa
     8281 tttgagattt cctaaaccct tttgaagatt agagaaaaag gtcactggac tttgtttttt
     8341 atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac tattctgtaa
     8401 ttcttctgta aagtactgcg ctaattctct ttcaaagact tcatactgat tcatcaattt
     8461 ttgataatca tcaaagaata ttggagtatc tttttcaata taatcaaaga cagtccatgt
     8521 cttatcatag cacaaagata aaaacttccg agagtctgca tgactttgtt tttggtgaaa
     8581 acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt ttgaaatttg
     8641 tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca tatcactagc
     8701 tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta cttcaaatga
     8761 cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta actgggatat
     8821 ttcaaaaata tctaaaatat ctcctcgaag actaaattcg ccctgagttt gtacttgagt
     8881 aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgat catattcttc
     8941 accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta aaatcaatcg
     9001 acttgctgcg atattacaaa ctaaaatccc tttcttagat gaatcagtca aaaaacgcaa
     9061 ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca ccataggagc
     9121 atcatctacc aaaaatggat agacgagttc ctcacccaag atagagataa gatcactaac
     9181 aagtccttct gcttctccat aagttgacgt caataacaca atcctatctt ctttttctaa
     9241 actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta gttgtctttt
     9301 cttatctgtt aaattttgat gccatttttt aatctgatca ttttctgaga ataaatctaa
     9361 taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt tctcttgtaa
     9421 atagtagttt acagaatcgt caactttgtc aacagactgt aaaataccga tataatcatc
     9481 cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag gtcttccaat
     9541 tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag acttgatacc
     9601 attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt ccatgtcaag
     9661 atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta ataaagcatg
     9721 aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa ttttttctcc
     9781 atttaggaaa aaggatgcta ggtcagcttg aaatatctta tcgtgtgtaa aagtgacatt
     9841 ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg tttcaaaata
     9901 tttatcccct ggatttccca agcctacaag taatttggtc atttatttta cctttcaaaa
     9961 gccaaaaggg ttggaatttt tttccaacct aattgacacc atttattaat ttttagacat
    10021 taaagcggaa ttccatgata tcgccatctt gaacgatata ttcttttcct tcttcacgca
    10081 agcgtccagc ttcttttacg gccttttcag atccgtattt cactagatct tcatatgaca
    10141 tggttactgc acgaataaag cctttttcaa agtctgagtg gataatacca gctgcttgag
    10201 gagccttcat accacgtttg aaagtccaag cgcgaacttc tttttcacca gctgtgaagt
    10261 aagttcccaa tccaagcaag tggtaagctg cacgcgtcaa cttatctaca cctgattctg
    10321 tcaaaccaat ggcttcaaga aactcttttt tatcttcatc atccaattca gaaatttctt
    10381 cctcagcacg cgcagaaata acgactactt cagcattttc tgtcgctgca aattcacgaa
    10441 tttgtttgac atagtcgata gagtcaggtt ctgaaaccac atcctcgtcc acattagcta
    10501 cataaagaac tggtttagtc gtcaaaagga aaagaccttt gacaaccttt tgttcctcat
    10561 ctgtaaattc aatggtacga gctgatttcc cgtcttctag gactggttta atcttttgaa
    10621 gaacattgaa ttctgctact gattctttat ctttttgcgt acgtgccatc ttttctacac
    10681 gcgcatatcg tttgttcact gattctaagt cagcaagaat taattccaga ttaattgtat
    10741 caatatctgc aagtggatct acaaaggcgt cttcacgtcc ttgctcgcgc atcacatttt
    10801 catcatcaaa agcacgaact acgtgaacaa tcgcatctac ttcacgaata ttggccaaga
    10861 atttattccc tagcccctct ccttttgaag ctccttttac aatccctgca atatctgtaa
    10921 attcaaatgt tgtgggaact gtctttttag gagttatcat ttcagttagt ttttgtaggc
    10981 gttcatctgg aacttccacc attccaacat ttggatcaat cgtcgcaaat gggtagtttg
    11041 ctgcctctgc tcctgctttt gtaattgcat taaatagtgt tgatttacca acgtttggca
    11101 aaccaacgat acctgctgtc aaagccatat ttctcattct ccgttttcat ttcaatccct
    11161 aatattataa cacaaaaagg gataaagtgc taaccctcta actaagggtt ctcagtcaat
    11221 aattttattc atttttcgct caaaatcata tcgccccatc atgacaacat gctcacaatt
    11281 actgcatttt attttgatat ctgctcctac acgtgtaatt tcccaacgat tagccttttt
    11341 accagtcgac ttgattgtac aagcgtgtga ttttttcatc tcaacaaaat ttccaacttg
    11401 atacatacta ctctcctttt ctttttcgat tatatcataa aagaggcgag ccaggctcaa
    11461 cctctttcac ttaatttgta cgaactggtg taataagctg catgaagtct tcgtcagtat
    11521 ctgctggcac aagagtaaat ggacgaacag ctgagataaa gctaatggtc accttttcgc
    11581 tatttaaagc tttaagagaa tcaatcaagt aagttgggtt gaaactaatg gtcaaatctt
    11641 caccagtaac ctgatcagta tcgatttctt cgtttacttt accaacttct ggagagtgaa
    11701 catgggcgct aacaacccca tccttaattt caagtttcac agtaccattt tgagtcgcac
    11761 ttgataaaag acgggcacgc tccattgact ggcgtaagtt taccacatta aaagtaatag
    11821 tagtgttaaa gtctgttgga atcaagcgat ctgtatcagg atagtttcct tctaggagac
    11881 gagtatagaa gctaatattt tcgcttctaa agaggatttg gttattggca aagaaaatct
    11941 ctacagtttc gatatcatct gtaaataccg ctgaaaattc gcgtagagaa cggctaggaa
    12001 ttacgacatc aaaatcatca ctattttttt caagagtcaa ttttttctgg cttaggcgat
    12061 gagagtctgt tgcaactgtt tttaactctt tgtgttgact caatacgaag tggacacctg
    12121 ttaaaatcgg acgactctct tgtgtacttg cagcaaaggc tgtttcatta ataattttct
    12181 tgagtaattt tgtttcaagt attaaaggag tgcttgctga aatttcttgg attcgtggat
    12241 attgttcgct atcttttcct tttagggtaa tttctgattt gccactggtt aaaacaattt
    12301 gattttgttc aatttcttta aaatcaagag ttacatcagg taaactagat actacattga
    12361 taaagaaaga agcttcaaga aggatcgaac ctaaagaagt aattaacaaa ccagcatctt
    12421 catttttttg agaaataaaa ttttcaattg aaatttgacc atttgaacca attaaagtaa
    12481 taccttcatt ggtcacgtca atttttactg ttgataaaat aggaatggca tttttagaac
    12541 taatagctct cttagtagta tttaatgctt gtagaaataa atttttatta attgaaaaat
    12601 gaatcatgga ttctccttta tttattttta gtattagaaa gataatagta ataatagagt
    12661 ctgtgaaatc tgtggaaaac agcctttaaa caagtcatat caagtttttt agcttgttta
    12721 aaaaatgtgg ataaaaaaga taaaaaacta aaagttatcc acaaattatt tgattttctt
    12781 tttgattgat tcaatttcta aacgtaaatt atcgtcttga tcaatcaaag attttatttt
    12841 ggcatgggca tgaatgactg tggtatgatc ttttccccca aattccttcc caatttttgg
    12901 aagactatta tctgttagtt ctctagataa atacatggct acttgacggg ccaaaacaat
    12961 attttgaagg cgtctacttc ccttcatttc tttgatacta acaccataaa agttaccaac
    13021 ttcagtttgg attttatcaa ttgggatgac gagcatttgg ctaacatctt gtttgcgggc
    13081 tctaatggct tctgcagcaa tatcaatagt gatatccttg atttttttta ctctggcaat
    13141 taaagtgatg tcgttgatgg ctccctcaag atctcgaaca tttgaatcaa attgcccagc
    13201 taggtattct agagtatcac tttggaaatt gtagcctaaa tgttccgttt tactttgtaa
    13261 aatggcaata cgtgtttcaa agtcaggggg tgtgatagtt tgtgtcaatc cccaactaaa
    13321 acgcgtgaca agcctctcct cgagcccttc tagatgtttt ggactacgat cactcgttag
    13381 gacaatctgt ttttgcttgt catgaagggc gttaaaggta ttgaaaaatt cttcctgagt
    13441 tgcgactttt tttccgctga gtgactggat atcatcgatt aacaaaagat caagactacg
    13501 ataggtcttt ttaaactttt ccatttcccc aagtcttagg tgatcaagaa agtcattaat
    13561 aaagctttcg gcagggatat atttaacacg cgcattagga atatttttta gaatttcatt
    13621 tccaatagcg tttaataagt gagtcttacc aaggcctggt cctccataga taaaaagagg
    13681 gttataggtc agagccaaat cttcagagac agctaaagcg gctgacacag cccaaacatt
    13741 tccatcccct tgaataaagt tatcaaaggt atacttttct tttaatcccg tatctgaata
    13801 aggaatagat actaactttg gactatagtt ataaagagtt aaatttgtag cttcttcaac
    13861 ttgtgagcta gtcgtatctt gaggtttggt gaaaatatag tggggagtta tttcagcgtc
    13921 ataaatttca aaaccagcta ctacaataat atcttttagt tgtttttccc agaccatttc
    13981 catttcagag cgaggtagaa atatagtggc aatattttcc tctaccttga tgagttcagc
    14041 ttgaatagca tagaaatcat acatggatcg agtcagtctt tcttgtgcaa attctaatat
    14101 acgattccaa aattgttttt ctttcaatcc tttctcctcc tttactattt aaaagtttaa
    14161 tactagagat attttaccat agatagcaag aattttccac aagctgtgaa aaataatcca
    14221 caatgttacc aaactttatc cacaggttgg ggataaaaga agaaattatt gatttattaa
    14281 gctttttatc gaaaaacata gtggataacc ttgtgagata aaaaaaataa aagaacagcc
    14341 ttatttcagg ctgttgataa ttctactata ttcttcttga tttgaaaaag aaataatgat
    14401 ttttccactg tcttttttag atagtttaat ttctacatct aatccgagta gttttcttaa
    14461 ctgtttttct tcattttgta tgaaatgatt agttttttgc tgtttctttt gttttttctc
    14521 tgtcagaaga gcttctaact tccttacaga aatatcttct tctataatcc gttgaaagaa
    14581 atagtcttgt tgttccttat ttaacccaac tagggaacgc gcatgggctt gtgatagttt
    14641 gccattttct acttctgaga gaatctgttc tggcaaggaa agtaaacgaa tggagttgct
    14701 gatatatgga cgagacttgc ccatcttatc tgcaatttca gcatgggtga atcctttctc
    14761 tacgagagat tcataggcgc gtgcttcttc tattgggttt aaattttctc tctgtaaatt
    14821 ttcaataatg gactgaacca tcatctcttg gtctgaaatc tgtttaacaa cagctgggat
    14881 agaccgtaga ccagctaaaa gtgaagcccg atagcgtctc tctcctgcaa ggatttcata
    14941 accaataaca ggagattgac gaacaataat cggttgaatg accccatttt ctttgataga
    15001 ctgtgctagt tcatctagtt tttctctatc aaattctttt cggggttgat agggattttt
    15061 ttgtatatct gtgatagaaa tcatttcaaa tttttccatg attctacact aacacatctt
    15121 ttctcttatg taaagctttc tttacataga tgtcaattaa gattctaaat cacctgaact
    15181 cttgttaagt ttgatagagg tagtttcttc tttcccgtta cgatagtagg ttatcttaat
    15241 ggtgtctccg atagaatggt tgtaaagagc actttgtaag tctgttgatg aagcaatctc
    15301 tttgtcatct acttttgtaa ttacatcgta tttttcaagg tgaccattgg caggcatatt
    15361 actttgtacc gaacgaacaa ctacaccaga tgtaacatta cttggaatat tgagtcttct
    15421 gatgtcgctt gtactcacat tagataaatt aaccatctgg attcccaaag ctggacgcgt
    15481 cacttttccg tttttttcta actgttcaat aatattgata gcatcatttg caggaattgc
    15541 gaaaccaaga ccttctacag atgttcctcc atttgtagca attttacttg aggtaattcc
    15601 gataacctgc ccttgaatat tgatcagtgg gccgccagag ttacctgggt taatagcagt
    15661 atcagtttgg atggcttttg tagaaatagc ttgtccatct tccgatttta aggatacatt
    15721 tctattgaga ctggatacga taccttgagt gacagtattt gcatattcag aacctaacgg
    15781 gctaccgatg gcaatagcag tttctcctac agttaactta ctagaatcac caaactcagc
    15841 tactgttgtc actttttctg aagagatttt gacgacagca atatcagaga aagtgtcagc
    15901 tccgacaatt tctccaggta ctttagtccc atctgacaat cgaatatcta ctttgctggc
    15961 gccatttata acgtgattgt tggtgacgat gtaagcttct ttatcattct ttttataaat
    16021 aactccagac ccttcactag agattcgctg agaatctgtg tcagtatcat cattgccaaa
    16081 tacgctattt tgtctgtttg ccgaataagt aataacagaa acaacagcat cttttacttt
    16141 gttaacagcc tgtgttgttg aattttcgtt cttataggca gtttgtgtaa tagtactatt
    16201 gttgttagag ttgtttacac tacttttttg agttagttga gttattgaaa aactacccaa
    16261 ggctccacta aaaaagctaa tgacgataac gactaataat tgaaaccatt ttttgtaaaa
    16321 tgtttttata tgtttcatat ttgcctccat atgtttgaat tactgaaagt ataaactgac
    16381 tagcttaatt ataacttaaa cacaaaagtt ttacacaaac tgtggataac tcttttgaaa
    16441 ctgtgatttt cttaattgaa atctattttt tattttgtga ataagatgtg aaaaaataga
    16501 gaatatgtta gaatagagtc atgaaaatta aagttgtaac agttgggaaa ctgaaagaaa
    16561 agtatttaaa agatggtatc gcagagtatt caaaacgaat ttctagattt gctaagtttg
    16621 aaatgattga gttatcagat gaaaaaacac cagataaggc cagtgaatca gaaaatcaaa
    16681 agattttaga aatagaaggt cagagaattt tatcaaaaat tgctgaccgt gatttcgtta
    16741 ttgtgttagc cattgaaggg aaaactttct tctcagaaga atttagtaag cagttagaag
    16801 aaacttctat aaaaggattt tctactctta cttttattat tgggggaagt ttaggattgt
    16861 catcatctgt aaaaaataga gccaatcttt ctgtcagttt tggtcgccta accttgcctc
    16921 atcagttaat gagactagtt cttgttgaac aaatctatcg cgcttttacg attcagcagg
    16981 gattccccta ccataaatag aaaattgact tttaattgaa tttttggtag aataattgtg
    17041 ttaggtctca tagctcagct ggatagagca ttcgccttct aagcgaacgg tcgcaggttc
    17101 gaatcctgct gggatcaata taatagcaaa gctgggaatt ttcccggctt ttttcttaaa
    17161 aaagtacact ttgggagaaa aaaatgacag ttgagagaat tttatctaaa acgaaattcc
    17221 attttgtata atggtttttg taagttagct tacaagaaaa aacattttag gagattttat
    17281 tatgaaaaac acagttaaat tggaacagtt tgtagctttg aaggaaaaag acttacaaaa
    17341 gattaaaggt ggggagatga ggctgtcaaa attcttccgt gattttattt tacaaagaaa
    17401 aaagtaatga aataagggga aagagtaatg gatttatttg gatttgggac agttattgtt
    17461 cattttttaa ttattagtca cagctaccat ttaatttgta aaggtcaaat aaatagaaaa
    17521 gaattattcg tttttggtgc ttatacatta ctaacagaaa tagtatttga ctttccctta
    17581 tatattctat atttagatgg gttagggatt gcaacatttt tatttccttt gggcttatat
    17641 tcctattttc gatggatgaa acagtatgag agggatagag gattattcct aagtttacta
    17701 ctatctcttt tatatgagag cactcataac tttctgtccg taactttctc ctctataaca
    17761 ggagataatt ttgttttaca atatcatttc ccattctttt tcgttgtgac ggtgttaacc
    17821 tattttgtta cattaaaaat catttattat ttccatttgg aactagccta ttttgacaag
    17881 gactaccttt atcctttctt gaaaaaagta ttttttgctt tactattgct acatattgta
    17941 tctttcgttt cagatatggt aagtacgatt aaacatttga atagttttgg aagtattttg
    18001 tcatctattg tctttatctc tctccttttg accttctttg caatgaattc tcataaagtt
    18061 caaatggaga aagagattgc tttgaagcag aagaaatttg aacagaaaca tttacagaat
    18121 tacacagatg aaattgttgg tctgtataat gaaatccgtg gttttcgaca tgattatgct
    18181 ggaatgcttg tcagcatgca gatggcaatt gacagaattt acaatgaagt tttagtcaaa
    18241 gcaaatcata aattgcgttc agataagtac acttactttg atttgaacaa catagaagac
    18301 tcagctttac gaagtttggt tgctcagtca attgtctatg ctcgaaataa tggtgtagag
    18361 tttacactgg aagtaaaaga tacgattacc aagcttccaa ttgaactatt ggatttggtt
    18421 cgtatcatga gcgttttatt gaataatgct gtcgaaggat cggctgatag ctataaaaag
    18481 cagatggaag tagcagttat taagatggaa actgaaacag ttatggtgat tcagaattca
    18541 tgtaaaatga cgatgactcc ttcaggagat ctatttgcct taggattctc cactaaggga
    18601 agaaatcgcg gagtcggatt aaataatgtg aaagaactac tagataagta caacaatatt
    18661 attttagaaa cagagatgga aggcagtaca tttagacaaa tcattagatt taagagggaa
    18721 tttgaatgaa agttttaatt ttagaagatg ttattgaaca tcaagtgaga ctagagagaa
    18781 tattggatga aatttcgaaa gaatcgaata ttccaatatc atacaagaca acgggaaaag
    18841 tccgtgaatt tgaagaatac attgaaaatt atgaagtaaa tcaactttat ttcctagata
    18901 tcgatattca tggaattgag aaaaagggat ttgaagtggc tcagttcatt cgtcattaca
    18961 atccttacgc tattatcgtc tttatcacta gtcgatcaga gtttgcgact ctaacctata
    19021 aataccaggt atcagcccta gattttgttg ataaggatat caatgatgag atgtttaaga
    19081 agagaattga gcaaaatatc ttctacacga agagtatgtt acttgaaaat gaagatgttg
    19141 tagattattt cgactacaat tacaagggaa atgatttaaa aattccttac catgatattt
    19201 tgtatattga aacaacaggg gtctctcata aattgcgcat tattggtaag aattttgcaa
    19261 aagagtttta tggtaccatg acagatattc aggaaaagga caaacatact cagcgatttt
    19321 attctcctca caagtcattt ttggtaaata taggcaatat cagagaaatt gatcgaaaaa
    19381 acttagaaat tgttttctat gaagaccatc gttgtcctat ttcaagatta aaaattagaa
    19441 aattaaaaga tattttagag aaaaaatctc aaaagtgatt gacaattagc aagaaattga
    19501 tataatggtt atatctgcta cagatagaag gtccgttggt caaggggtta agacaccgcc
    19561 ttttcacggc ggtaacacgg gttcgaatcc cgtacggact attttatccg ccatagctca
    19621 gttggtagta gcgcatgact gttaatcatg atgtcgtagg ttcgagtcct actggcggag
    19681 tatagataaa agggaacaca gctgtgttcc tctttttata tcaatttgta tcaccaagca
    19741 ttttcataag gaagtctgtt atttcttgag aactttcttt ttttccatgt gcaatccaag
    19801 tttggcagac accaaaaagt gcatgagtta gatagatgct actatattct aattcagtgg
    19861 tatttagatt cagttgcata aatcgctttt gtaaatctgt actgagcatg atatgaagtt
    19921 tatttcgtaa gaaattttgg atttctttag tcccattttc agaaagaagg gcagccagaa
    19981 gtggttctga ctctagatat ttaaaaactt ctaaaatagc gtctcttttg tgatgagcat
    20041 gtttttgaaa aatatattca aatgtatgga atagcttgct ttgatagtgc tcaatcatat
    20101 catacttatc cttatagtga gtatagaagc tggaacgact aattccggct ttttctacta
    20161 atttgacagt agaaatttta tcaaatggct gttccatcag taattgtacc atagcatttt
    20221 caatagttcg ctttgttttt aagcgtttgt tactttcttg catatttcct tcttgtaaac
    20281 aaattagact atatgtctaa aaatagattt tttatcttgt aatttagatt ttttaatgta
    20341 taatctatta tatcaaaatt ttagacaata tgtttaaaaa aggagaaact aagtttaaag
    20401 aatggaaagc aatttaaaaa aaaccaacct ttattattgt catgatcggg atttctctta
    20461 ttccagatct gtacaatatc atatttttgt catcaatgtg ggatccatat gggcaattgt
    20521 ctgacttacc tgtggcagtt gtaaataatg ataaagaggc ttcctataat ggtaatacta
    20581 tggcaatagg aaaagacatg gtgtccaatt taaaagaaaa taaaaccttg gattttcatt
    20641 ttgtagatga agaggaagga aagaagggat tggaagatgg cgattactat atggtagtga
    20701 ctttaccaag tgatttatct gaaaaaacaa ctacattatc caatattcaa tcgacagcag
    20761 cttatcaatc attgacaagt gagcaacaaa ctgagataag tgattctgta tctcaaaatt
    20821 caactgatag tattcaatcg gctcagtcaa ttgtagcttt agtacaagat ttacagggaa
    20881 gtttagaaaa cttacaaaat caatcttcta atctttcgac tttaaaaaat caagctaatc
    20941 aagtattacc tattacttct acttctttga taggattgtc aagtggatta acagagatac
    21001 aaggagatgt tactagcaaa ttagttcctg ccagtcagtc gattgcatca ggtgtaaacg
    21061 catatactac aggtgttgat aaagtttctc agggcgcaag tcaactaagt gaaaaaatgc
    21121 caccttgaca gatagtttgg ataaactagt ttcaggctca aacaccttga cacaaaaatc
    21181 ttctagattg acagcaggag ttggttaatt acaatcagga tctgggcaat tagcagacaa
    21241 atccagtcag ttactttcag gtgcttctcc attagagaat agagctaata aattggcaga
    21301 tggatctggg aaactagcag aaggtggaac aaagttaact tctggattgg aagatttaca
    21361 gacaggactt gcttctttag gacaaggact aggtaatgct agtgatcaac tcaaatcagt
    21421 atcaacagaa tctaaaaatg cagagatttt gtcaaatcca ctcaatcttt caaaaacaga
    21481 caatgatcaa gttcctgtaa atggaatcgc aatagctcct tatatgatat cagttgctct
    21541 ttttgttgca gcaatatcaa caaatatgat atttgcgaaa ttgccttcag gacgtcatcc
    21601 agagagccgt tgggcttggt tgaaatcttg agctgaaata aatggtatta tagctgtttt
    21661 ggcaggaatt ttggtatatg gaggagttca gcttattggt ttaactgcta atcatgagat
    21721 gagaatattt attctcatca tcctaacaag tttagtattc atgtctatgg tgaccacttt
    21781 agcaacgtgg aatagccgta taggagcttt tttctcactt attttgcttt tactacagtt
    21841 agcatcaagt gcaggtactt atccacttgc tttgacaaat gatttcttta gatctattaa
    21901 tccctggtta ccaatgagct attcagtttc gggattacga caaacaatct ctatcaacaa
    21961 gtcattttcc tagctgtcat actagctcta tttactggtt taggtatgct agcctatcaa
    22021 cataagaaaa tggaagaaga ttaaaaaaat cgaccgatta actggtcgat tttttatgcc
    22081 ttagatgact ttcgtctgtg attatagatt ccaaatagta agagagaagt aaaggaacag
    22141 attgctccag taataaaacc attgggaatg aaggaaagtg taatagttcc tttccccttg
    22201 ggaatgtcaa ctttcataaa tccagtttga gcttgtttaa tttctatttt cttaccatct
    22261 tggtaggcag accaaccttt gtcataagga atggtgaaga aaatagatgt atcttgttgg
    22321 acatcatatg tagcaaaaac cttgttttta gaagttgata ctgtgacagg ttgttcttta
    22381 attttttgaa ttgcctcggt gaaagttttg gtatctaaac gatagaaggt aggagattca
    22441 aatgatactt gtgaatttcc agggaaacta acattgatat tgaaagtttt tttctcttta
    22501 gtatatccta gattaaagaa ggagaagaca ttatcagttg taaaagtctt tttttcacca
    22561 tttacaagga tgtcaacctt cttttgttta tcgttagaaa agtgaaggtt tatgaaagag
    22621 agataaactt ggctgttttc tggaacttca atttgatact ggattgctgc atcttcattt
    22681 gaagaacttg tgacactaat caaatcatta gtattttcta ttttttctgt tttttcataa
    22741 ggtattggag aaaaataatc aaaattgacg ttagcaagtt gatttaaaaa tgaggcctga
    22801 ttatccaagg tatgttcatt gaacttgaca tcattgtaaa cagattgact agcaactgca
    22861 atcggaagag agtattgatt ttcatatagg gtaagattat ctttttgata gatatcttta
    22921 aagccatact tatcaatagg actgtctgag atattgtact ggataccaaa taaactatca
    22981 gccaaaatac tattatttgc atatcggaga ttgagattag tcccagagga tttaaaacca
    23041 agtttatcta aagtagagct tgatgaacga tttcgaacag atgaaaattg agagattcca
    23101 ttgtagttga atttcatact gtcatttcct gtctgagttt gtagtttttc agtacgagta
    23161 aattgatttc caatatatgt tgagaaagat tccatagctg ggatatctcg actataagca
    23221 cttcgagaag caaatcccca ttccttagca attccgtcca tttgagatga agcatttaaa
    23281 ctcatttcaa ccagtataaa taaagagatt agaatggcaa atagattcac agatataaac
    23341 tttttgataa ctgcaaggag taaaagagaa tagacaacca aaaattcaag agtaagcaga
    23401 atattcaaat ctgttaaaaa agaataatgc gattttagat agatggtagc taaaaatcct
    23461 gttactacaa gaaaaagcga aactaaaaaa ttccagactt taagttcttt cagacgcttt
    23521 aagacttctg ctgctgtgta aattaacaag gtagagaaaa tccaagcata gcgatgtaaa
    23581 aacatgtttg gagtatgcat gccttgccaa aataagtcaa gagcttctat gtaaaagctt
    23641 gcaattagaa atgcaaagaa tattatatat atgagtttca cgtgaaactt aatagatttc
    23701 agcgtaaaaa ataaaatggt caaaataaag ggaagtagtc caacaaaaat cattgggatg
    23761 gccccatact ttgttgtgtc aaaggaacca atgaattgct tagcaaagag atcaagatac
    23821 cagctacttt cagtttgaaa ctttgtaact tcagtcaatt tttccccatg tgtctgtaaa
    23881 tcaaacagag tgggaagagt cataatcaaa ctagccatac cagctaaaaa ggagataact
    23941 atgaaatcaa gaacagatga ttttcgagtc ttaaagtccc acgaaatttg acagagatac
    24001 cagaaaataa gaaacaatac tgtcatatat ccaaaataat aattttgaat aaataagatt
    24061 gacagacttg taaagtacaa taggagtttc ttttcagtta tcagtagatg taaaccagtt
    24121 ataattaaag gaatcaagat aaaaacatct agccaggttt ttatctctaa ttgactgaca
    24181 gtgaaactca tcagagcata ggaagtagat aaggctagct ttaaagtctg agggatagat
    24241 tgaaacaatt tattcaaact aaaaaaggtt gacagaccaa tcaatccaaa ttttaagaga
    24301 gtggtcagat agacagcatc tggcatattc gttagatcaa aaaagtaaac tagaggcgcg
    24361 agaaaactac ccaagtaata actagatagg gcatagaagt ttagccctag accacttgta
    24421 aaggtgtaaa acagactact atttccatgt aggatatttc gtaaggctac atcaaaaata
    24481 acgtattgat gaaagccatc tcctaataga ggagagttgt cgctattcca gtagatacct
    24541 tgagatagat atactccaga cataatcact acaggaatga tgaaagaaat aaaataggtt
    24601 cgatatgttt ttaaaaatga tttcatgtta cctcgtagaa tgatagaaaa ctcagttggt
    24661 taacccaact gagttttgaa gttttattta gtctttccaa agttctttaa cttttgcttg
    24721 tacttctgca ttttctagga attcatcgta ggtttcatcg atacggtcaa tgacgccatt
    24781 tttagataag acaatgatat ggttagccaa agtttgaata aattcgtggt catggctagc
    24841 aaagatgatt gattctttaa agtttttcaa tccatcattc aagcttgaga tagattccaa
    24901 gtccaagtga tttgttggat catcaagtac aaggacattt gattttaaga gcatgagttt
    24961 tgaaagcatg acacgaactt tttctccccc tgacaagaca tttacaggtt tgttaacttc
    25021 atctccagag aagagcatac ggccgaggaa accacgtagg aaagtattgt catcttcttc
    25081 tttacttgcg aattgacgca accagtcaag aattgattct cctcctgcaa aatcagctga
    25141 gttatctttt ggtaggtaag attgactagt tgtaactccc cacttgacag ttccttcata
    25201 gtcaatatct cccatgattg cacgaattaa tgcagtcgtt tgaatatcat tttgtccaat
    25261 aagtgctgtc ttatcatctg gacgcaagat gaaactaata ttatccaaga tagtttcacc
    25321 atcaatcttt acagttagat tttctactgt caagagatca ttaccaatct cacgttccgc
    25381 tttaaagttg ataaatggat atttacgact agatggtaca atctcttcta gctcaatctt
    25441 atcaagcatt ttcttacgtg atgttgcctg ccttgactta gaagcattgg cagagaaacg
    25501 agcaacgaat tcttgcaatt gtttaatttt ttcttctgct ttagcattac ggtctgctag
    25561 caatttagca gcaagctcag aagattcctt ccagaagtcg tagtttccga catagagttt
    25621 gatttttcca aagtcaaggt cggccatgtg agtacaaact ttgtttaaga agtgacggtc
    25681 gtgggatact acgataactg tgttatcaaa gtcaattaag aagtcttcta accaagtaat
    25741 cgattggata tccaaaccgt tagtaggctc gtccaagaga agaacatctg gtttaccaaa
    25801 aagtgctttg gcgaggagaa cctttacttt ttcaccgttg gccaattcgc tcatgttttg
    25861 gtagtgtaat tcttctggaa tgtttaggtt ttgaagtagt tgagaggctt cactctctgc
    25921 ttcccaacct ccaagttcgg caaactctcc ttcgagttcg gcagcacgaa ccccgtcctc
    25981 gtctgagaaa tcttccttca tgtagatagc atctttctct ttcatgatgc tataaagttt
    26041 ttcatttccc atgataacga catcaatggc acgttcatct tcgtagtcaa agtgattttg
    26101 acgaagaaca gagagacgtt catctggacc aagagagatg tgaccagtag taggttcgat
    26161 atctccagct aaaattttta aaaaggttga ttttccggca ccattagcac cgattaatcc
    26221 gtaagtattt ccttctgtaa atttgatatt gacatcatca aaaagtttgc gatcactaaa
    26281 acgtagtgaa acatcagata ctgtaagcaa tatttttctc ctatatgtgt aatatattta
    26341 ttctactaga aaatacagaa atattcaaat ttttatttgt caattttgtg taaattatat
    26401 ttacagtatc ctttacacaa atctgtaaaa agcaaggctg atttattttg ataaattacg
    26461 gttatttcat taaaaaaatg ctataattga aaggactata tcgaaggaga acaaaatgac
    26521 taaacccatt attttaacag gagaccgtcc aacaggaaaa ttgcatattg gacattatgt
    26581 tggaagtctc aaaaatcgag tattattaca ggaagaggat aagtatgata tgtttgtgtt
    26641 cttggctgac caacaagcct tgacagatca tgccaaagat cctcaaacca ttgtagagtc
    26701 tatcggaaat gtggctttgg attatcttgc agttggattg gatccaaata agtcaactat
    26761 ttttattcaa agccagattc cagagttggc tgagttgtct atgtattata tgaatctagt
    26821 ttcgttagca cgtttggagc gaaatccaac agtcaagaca gagatttctc agaaaggatt
    26881 tggagaaagc attccgacag gattcttggt ctatccaatc gctcaagcag ctgatatcac
    26941 agctttcaag gctaattatg ttcctgttgg gacagatcag aaaccaatga ttgagcaaac
    27001 tcgtgaaatt gttcgttctt ttaacaatgc atataactgt gatgtcttgg tagagccgga
    27061 aggtatttat ccagaaaatg agagagcagg gcgtttgcct ggtttagatg gaaatgctaa
    27121 aatgtctaaa tcactaaata atggtattta tttagctgat gatgcggata ctttgcgtaa
    27181 aaaagtaatg agtatgtata cagatccaga tcatatccgc gttgaggatc caggtaagat
    27241 tgagggaaat atggttttcc attatctaga tgtttttggt cgtccagaag atgctcaaga
    27301 aattgctgat atgaaagaac gttatcaacg aggtggtctt ggtgatgtga agaccaagcg
    27361 ttatctactt gaaatattag aacgtgaact gggtcctatt cgtgagcgcc gtattgaatt
    27421 tgctaaggat atgggagaag tttataatat gattcaaaaa ggtagtgaaa gagcgcgtga
    27481 agttgcgggt caaaccctat ctgaggtaaa aggggcaatg ggacttcatt actttaacta
    27541 agtttatttt acaagaaact atcttttcta tctcgaagaa aagatagttt tttatttacc
    27601 cctgtaacat ttgacaaatt tttatagaat ggtatgatag atacaatata aaaagagtca
    27661 agctcaaaaa gaaagaaaag aggaaacttc gaatgtctaa ttgggacact aaatttttga
    27721 aaaaaggttt tacctttgat gatgtattgc ttattccagc tgaaagtcat gtgttgccta
    27781 acgatgcaga tttaacaact aaattggcag ataatttgac tttaaatatc ccaattatta
    27841 ccgctgccat ggacacagtt acagagagtc aaatggccat tgctattgct cgtgcaggcg
    27901 gtctcggagt tatccataaa aacatgtcaa ttgctcaaca agcagacgag gttcgtaagg
    27961 taaaacgttc tgaaaatgga gttattattg atccgttctt cttgacgcct gaacatacaa
    28021 ttgctgaagc agatgagctt atgggtcgtt accgcatcag tggtgttcca gttgttgaaa
    28081 cacttgaaaa tcgtaaattg gttggtattt tgacaaaccg agatcttcgt tttatttcag
    28141 attataatca accaatttca aaccatatga ctagtgaaaa tcttgttact gctcctgtgg
    28201 gtacggatct tgcaacggct gagagtattc ttcaagagca tcgtattgaa aaacttccgt
    28261 tggtcgatga agaaggcagt ctttctggtt tgatcactat caaagatatt gaaaaagtta
    28321 ttgagtttcc aaatgcggct aaagatgagt ttggtcgtct tctagttgca ggtgcagtag
    28381 gtgttacttc agatacattt gaacgtgcag aggctctttt tgaggcagga gcggatgcga
    28441 ttgttattga tactgcacat ggtcattctg caggtgtctt gcgtaaaatt gccgagattc
    28501 gtgctcattt cccagatcgg actttgattg ctggaaatat tgctactgct gaaggtgcac
    28561 gtgcccttta tgaagcgggt gtagacgttg ttaaggttgg tattggacca ggttctatct
    28621 gtactactcg tgtgattgct ggtgttggtg ttccgcaagt aacagctatc tacgatgctg
    28681 cagctgttgc gcgcgaatat ggtaaaacga ttattgctga cggtgggatc aagtattctg
    28741 gagatattgt aaaagcactt gctgcaggtg gaaatgctgt tatgcttgga tctatgtttg
    28801 ctggaactga tgaagctcca ggcgaaactg aaatcttcca aggacgtaaa ttcaagactt
    28861 accgtggtat gggatcaatt gctgctatga agaaaggttc aagcgaccgt tatttccaag
    28921 gttctgtcaa tgaagcaaac aagcttgttc cagaaggaat tgaaggtcgt gttgcttata
    28981 aaggagcggc agctgatatt gttttccaaa tgattggtgg tattcgctct ggtatgggtt
    29041 actgtggtgc agctaatctt aaagaactac acgataatgc tcaatttatt gaaatgtctg
    29101 gtgctggttt gaaagaaagc catcctcatg atgtgcaaat tactaatgag gcaccaaatt
    29161 attctatgta aaaacaatga aaagaactcc agtgaaaaca ggagttcttt tacaatgttg
    29221 tcaatttcca tttacagcag ctttaccatc ctgaatagtg aagatactta gattttctgg
    29281 cagattttga agatggtcta agcttgttgt tgtgataaag gtttggattg attgagaaat
    29341 cgtttctaat aattttaact gtctagtgtt gtcaagttca ctcatcacat cgtcaagcag
    29401 taatatcgga gattctgtgg taatgctttc cattaattcg atttctgcta attttatcga
    29461 gaggacgaga ctacgatgtt gaccttggct tccgaaacta gcatccatcc catttatata
    29521 aaaagaaatg tcatctcgat gaggaccgac accagtattc tttttaaata aatctctgga
    29581 tctacttttt tctaaagcaa ttttgaaaga ttcggataag ttttgtttgt cagttgtatt
    29641 gacagaagat tgataggata ttgacaactc ttcgatctga ttagagagtt caaaatgttt
    29701 cttacgccca aatgattcta gtttttttat gaaatctaag cggtgattca ttacacgaca
    29761 tccataatca actagctgat catctaacac agaaaggaat gtttcatcta ttttttgaac
    29821 tgattttagg taagtgtttc tttgctttag gatgtggtta taattggtta agtcagataa
    29881 atagattggc ttaatttgcc caagctccat atcaatgaat tttcgtcgaa tcgaaggtgc
    29941 tcctttaatt agttgtaaat cttcaggagc aaataagaca acattcatgt gtcctacata
    30001 atctgaaagg cgtgcctgtt ttaagtgatt aacttttgtt acacggcctt tttgtgttag
    30061 ttcgatttct aggggaatgg atccagtttt tttctgaacg agacctgaaa gatgaagttg
    30121 ttcctcatca aaatgaatga gatttttatc tgttcgagtt cgatgactac gcgttaaggc
    30181 taaaaaatag atagcctcta acatgtttgt ttttccttgt gcattacgtc ccaaaaagac
    30241 attcaattta ggattaaagt ctattttcgt ttctttgtaa ttacgaaaag tcttgagaga
    30301 tagatgttgt agccacatga ttatctacca gggaatcgtg gagcttgttg gcttttaggt
    30361 gatgaagcag gtttcgattt gtctttttta actcccttat tcatcttttt gacaagttta
    30421 gcgatccgtt ctttttcaac tttatcagct tggtattcat cttgttcttc agaagtaggt
    30481 tgtgtcaaca agatgtcaat gttcatgtca gggatgtcaa ctttatcgcc aatacgaagt
    30541 ttttttccac gacgactctc taattcccta ttaaagtaaa cagaatgttc agagagaaat
    30601 gatttaatag ctcctccgct atgtgtaatt ccaagttctt tgagtagtgc ttggagggta
    30661 ataaattctt caaataattt gtattccata attcacctca atctttggta ttataccata
    30721 ttttcctaaa aatagtgaga gagatagcta gaaatgtaag cgatttttat ttcaaaagtg
    30781 ttacagggaa caagaaaatt tcaggttttc gtgatataat agaagtctgt atataaggag
    30841 gtaaatcatg gagttagtgc atggaatttc aacacatttt atccaatcaa aaaagtttaa
    30901 aacaaacaaa attaccgtgc gttttaccgc tccattatcc cttgatacga ttgcaggtca
    30961 catgttgagt gcaagtatgc tagagactgc taatcagatg taccccactt ctcaagattt
    31021 gaggagacac ttggccagtc tatacggtac agatatgtca accaattgtt tcagaagagg
    31081 gcaaagccac attatagaat tgacatttac ctatgttcgt gatgagtttt taagtaggaa
    31141 aaacgtgcta acctctcaga ttttggaact tgtaaaagaa actctttttt cacccgtagt
    31201 agttgataat gggtttgatc cggccttatt tgaaattgag aaaaaacaat tgctagcaag
    31261 tttagcagct gatatggatg attcttttta ttttgcacat aaagaattgg ataaattgtt
    31321 ttttcatgat gaacgtcttc aattggaata tagtgattta cgaaatcgta ttttagctga
    31381 aactccacaa agttcttact cttgtttcca agaattttta gccaatgatc gaatagattt
    31441 ctttttccta ggtgatttta atgaggttga aattcaaaat gtattagaat catttggctt
    31501 taaaggtcga aaaggagatg tgaaggttca gtattgtcaa ccttattcta atatccttca
    31561 ggaaggtatg gttcggaaaa atgtgggaca atccattttg gaattaggtt atcattaccg
    31621 ttctaaatat ggtgatgaac aacatttacc catgattgta atgaatggtt tacttggtgg
    31681 atttgctcac tctaagctct ttacaaatgt ccgtgaaaat gctggattag cttataccat
    31741 ttcaagtgaa cttgatttat ttagtggatt cttgaggatg tatgctggta tcaatcgaga
    31801 aaatcgtaac caggctcgta aaatgatgaa taatcaactg cttgatttaa aaaaaggtta
    31861 ttttacagag tttgagttaa atcagaccaa ggaaatgatt cgttggtcgt tgttactttc
    31921 tcaagataat caatcttcat tgattgaacg tgcttatcaa aatgccttat ttggaaaatc
    31981 ttcagcagac tttaaaagtt ggattgcaaa gcttgaacaa attgacaaag atgctatttg
    32041 tagagtagct aataatgtga aactacaagc gatttacttt atggaaggaa tagaatgaca
    32101 aaggttgttt ttgaagaaaa atactatcca gctgtaaaag aaatggttta tcgaactcgt
    32161 ttggccaacg gattgacagt tgctcttttg cctaaaaagg aatttaaaga ggtttacggg
    32221 agtgtcactg tacagtttgg ttcggtagat acgtttgtca cagaagttga cggagatgta
    32281 aaacaatatc ctggaggaat tgctcatttt cttgaacata aattatttga gagagaagat
    32341 tctagtgatt tgatgtcggc ttttacgagt ctaggtgcag atagtaatgc ctttacaagc
    32401 tttacaaaaa caaactatct tttttcagca acggattatt ttttagaaaa tttagattta
    32461 cttgatgaat tggtaacatc agcacacttt actgaagctt ccattctgac agagcaggat
    32521 attattcagc aagaacgaga aatgtaccaa gatgatccag attcgtgttt attcttttca
    32581 actttagcga atttgtatcc tggtacacct ttagcaactg atatagttgg aagtgaggag
    32641 tccatttccc aaatcaatct aactaatttg caagaaaatt ttacaaagtt ttacaaacct
    32701 gtaaacatgt ctctgttttt agttggtaat tttgatgtgg agcgagtaca ggactatttt
    32761 gaaagcaaag aactgaaaga ttcagatttt caggaagtag caagagaaaa gttgttttta
    32821 cagcctgtaa agccaacaga tagtatgaga atggaagtat cttctcccaa actagcgatt
    32881 ggagttagag gtaagcgaga agtttctgaa gcggattgct atcgacatca tattttatta
    32941 aaattattgt ttgcaatgat gtttggttgg acttcggatc gttttcaaaa atgttatgaa
    33001 tcaggtaaaa ttgatgcatc cttatctctg gaagttgaag taacaagtcg ctttcatttt
    33061 gtcatgttga caatggatac gaaagagcca gttgctttgt ctcatcaatt taggaaggct
    33121 attcgtaatt ttacaaagga tttagatatt acagaggaac atttagatat tatcaaaaga
    33181 gagatgtttg gcgaattttt cagtagcatg aactctcttg aatttattgc aacgcaatat
    33241 gatgcttttg aaaatggtga gacaattttt gatttgccga aaattttaca ggaaattact
    33301 ttagaggatg tccttgatgc tggacatcat ttaatagatg atggtgacat agttgatttt
    33361 acaatattcc catcgtagta acctattata atagacacta gaaagaaggg atgacaagta
    33421 tgagaaaaaa aacaattgga gaggttttac gattagctag aatcaatcag ggattgagtt
    33481 tagatgaatt gcagaaaaag acagaaatcc agttagatat gttggaagca atggaagcag
    33541 acgatttcga tcaacttcca agtccttttt acacgcgttc tttcttgaaa aaatatgcat
    33601 gggctgttga gttagatgac caaattgttt tggatgctta tgattctggg agtatgatta
    33661 cttatgagga agtagatgtt gatgaagatg agttgacagg tcgtagacgt tcaagtaaga
    33721 aaaagaagaa aaaaacatca tttttacctt tattttattt tatccttttt gctttatcga
    33781 ttttaatttt tgtgacttat tatgtttgga actatattca aactcaacca gaggagcctt
    33841 ctctttctaa ttacagtgtg gttcaatcaa caagttcaac tagctctgtt ccccactcct
    33901 caagtagtag ttcttctagt atagaatcag ctataagtgt atcaggcgaa ggaaatcatg
    33961 tagaaatcgc ttataagaca agtaaggaaa cagttaaatt gcaattggca gtttcagatg
    34021 ttacaagttg ggtcagtgtt tcagaaagcg aacttgaggg cggtgtaacc ttatcgccaa
    34081 agaagaaaag tgcagaagca acagttgcaa ctaaaagtcc tgtaacaatt acgttaggtg
    34141 ttgtaaaagg tgttgatttg acagtagata atcagactgt tgatttatcg aaattaacag
    34201 ctcagactgg acaaatcact gtaaccttta ctaaaaatta aggaaaaacg aatgaaaaaa
    34261 gaacaaattc ccaatctctt aacaataggt cgaattctct ttatacctat ttttatcttt
    34321 attttaacga taggaaattc gatagagagt catatagttg cagctattat ctttgctgtt
    34381 gccagtatta ccgactattt agatggatat ttagctcgta aatggaatgt ggtcagtaat
    34441 tttggtaaat ttgcagatcc tatggcggat aagttactag ttatgtcggc ttttattatg
    34501 ttgattgagt taggtatggc tccggcttgg attgttgcag tgattatctg tcgtgagtta
    34561 gctgtgacag gtttaaggct tttattggtt gaaactggtg gaacaatttt agcagcagca
    34621 atgcctggaa aaattaaaac ttttagtcag atgtttgcca ttattttctt gctattacat
    34681 tggactttgc ttggtcaagt tctactttat gtagccttat ttttcactat ctactctggc
    34741 tatgactatt tcaagggtag tgcctatgta tttaaaggga catttggttc gaaatgaaat
    34801 caataattga tgtaaaaaat ctttcttttc gctataaaga aaatcagaac tactacgatg
    34861 tgaaggatat tacgtttcac gtgaaacgtg gagaatggct ttcgattgta gggcataatg
    34921 gtagtggtaa atcaacgacg gttcgattaa ttgatggctt actggaagca gaatccggag
    34981 agattgtaat tgatggccaa cgtttgactg aggaaaatgt ttggaatata cgtcgtaaaa
    35041 tcggtatggt ttttcaaaat ccagacaatc aatttgttgg agcgactgtt gaagatgatg
    35101 ttgcttttgg tttggaaaat cagggacttt ctcgtcaaga aatgaaaaag agagtggaag
    35161 aagctctggc tttagttggc atgttggact ttaaaaagag agagccagcg cgtctatcag
    35221 gtggccaaaa gcaacgtgtg gccattgcag gtgttgtagc cctaagacca gatattttaa
    35281 tcttagatga agcaacgagt atgttggatc ctgaggggcg tagagaactt attgggacag
    35341 taaaaggaat tcgaaaagac tatgatatga cggtcatttc tattacccat gatttggaag
    35401 aagtcgccat gagtgatcgc gtattggtca tgaaaaaagg ggaaattgaa tcaactagta
    35461 gtccaaggga gcttttctct cgaaatgatt tagatcaaat tggattagac gatccttttg
    35521 ctaatcaatt aaaaaaatct ttgagccaga atggctataa tttacctgaa aattatttga
    35581 cagaaagtga gctagaggat aagctatggg aattgctcta gaaaatgtga attttacata
    35641 tcaagaaggt actcccttag cttcagcagc tttgtcggat gtttctttga cgattgaaga
    35701 tggctcttat acagctttaa ttgggcacac aggtagtggt aaatcaacta ttttacaact
    35761 cttaaatggt ttattggtgc caagtcaagg gagtgtgagg gtttttgata ccttaatcac
    35821 ctcgacttct aaaaataaag atattcgtca aattagaaaa caggttggct tggtatttca
    35881 gtttgctgaa aatcagattt ttgaagaaac ggttttgaag gacgttgctt ttggaccgca
    35941 aaattttgga gtttctgaag aagatgctgt gaagactgcg cgtgagaaac tggctctggt
    36001 tggaattgat gaatcacttt ttgatcgtag tccgtttgag ctgtcagggg gacaaatgag
    36061 acgtgttgcc attgcaggca tacttgccat ggagccagct atattagtct tagatgagcc
    36121 aacagctggt ctagatcctc tagggagaaa agagttgatg accctgttca aaaaactcca
    36181 ccagtcaggg atgaccatcg tcttggtaac gcatttgatg gatgatgttg ctgaatatgc
    36241 gaatcaagtc tatgtaatgg aaaagggacg tttagtaaag gggggcaaac caagtgatgt
    36301 ctttcaagac gttgttttta tggaagaagt tcagttggga gtacctaaaa ttacggcctt
    36361 ttgtaaacga ttggctgata gaggcgtgtc atttaaacga ttaccgatta agatagagga
    36421 gttcaaggag tcgctaaatg gatagtatga ttttagggcg ttatatccca ggggattcga
    36481 ttgttcaccg attggatcca cgtagcaaat tgcttgctat gatgctactg attttgattg
    36541 tgttttgggc taataacccc ttgacgaatc tgattctttt tatagcgaca gggatattta
    36601 ttgccttgtc aggagtatct ctttcatttt ttattcaggg cttgaagtct atgtttttct
    36661 tgattgcctt cacaactatt tttcaactat ttttcatttc taatgggaat gttttatttg
    36721 agttttcgtt tgtgagaatc acggattatg ctttgcaaca agctgggatt attttttgtc
    36781 gctttgtatt gattattttc ttttcaactt tgttaacctt aacaaccatg cctttaagtt
    36841 tggcatcagc tgtcgaagct ttattagcac ctttaaagcg tgtgaaagtt ccagttcatg
    36901 aaattggatt gatgctgtct atgagtttgc gttttgtccc aaccttgatg gatgatacga
    36961 cgcggattat gaatgcacag aaagctcgtg gagtggattt tggagaagga agcatcgttc
    37021 aaaaagtaaa ggcgatgatt cccattttga ttcctctttt tgcgacaagt ttaaaacgtg
    37081 cagattcctt ggctatcgct atggaagcgc gtggctatca gggtggaaaa ggcagaagtc
    37141 aataccgaca attgaaatgg actctaaagg atacgttgac cattcttgtt attctcgtac
    37201 ttggttgttg tttatttttc ttaaaatctt agtagctttc aggaattgat aaaaagttac
    37261 tgtaacagtt tttgatataa aggtaggaat atgaaccgtt ttaaaaaatc aaaatatgtc
    37321 attattgttt ttgtcactgt tctgcttgtg tcagctctct tagcgacgac ttattcaagt
    37381 acaattgtga caaaattagg agatggaatc tcattggttg atagagttgt acaaaaacct
    37441 tttcagtggt tttattctgt caaatcagat ttggctcatt tgacacgaac atataatgaa
    37501 aatgaaagtt tgaagaaaca gctttaccaa ttagaagtta aatcaaatga ggtggaaagt
    37561 ttaaagacag aaaatgaaca actgcgccaa ttgcttgata tgaagtctaa attgcaagcc
    37621 acaaagactt tagcagcaga tgttattatg cgttctccgg tatcttggaa gcaggagttg
    37681 accttagatg caggtagatc aaaaggtgct tctgagaaca tgttagctat tgcaaatggt
    37741 ggcttgattg ggagtgtttc aaaagtagag gagaactcta ctatagtcaa ccttctgaca
    37801 aatacggaaa atgctgataa gatttctgtt aaaattcaac atggctctac tacaatttat
    37861 ggaattatta ttggctatga caaggaaaat gacgttctta aaattagcca attaaatagt
    37921 aatagcgata ttagtgcggg agataaggtg actactggtg gattaggaaa ctttaacgtt
    37981 gctgatattc ctgttggtga agtggttgcc acaacgcata gtacagacta tttgacacga
    38041 gaagtaactg ttaaattgag tgcagatact cataatgtag atgtgataga attagtgggg
    38101 aattcataat gagacagttg aagcgagttg gagtattttt attgcttcct ttctttgttc
    38161 taattgacgc ccatattagc cagcttctgg gctcattttt cccccatgta catttggcta
    38221 gtcattttct ttttctattt ctcttatttg agacgataga agtatcagag tatctctacc
    38281 tagtctattg ttttgttata ggcttggttt atgatgttta ctttttccat ctaataggga
    38341 ttacaactct cttatttatc ttattgggag ccttccttca taaattgaat agtgttattt
    38401 tgttgaatcg ttggacaaga atgctagcta tgattgtgct gacattcctg tttgaaatgg
    38461 gtagttatct tttggctttt atggtagggt tgacagtaga tagcatgtcg atttttatag
    38521 tctatagctt ggtaccgacg atgattttaa attttttatg gattactgtt tttcaattta
    38581 tttttgaaaa atattatcta taagaacgac atataaatgt aacaaaggcg taatatttat
    38641 taggcctttt tttggtatac tagtattgtc tttaaaagaa ggagtatcta cgtaatatga
    38701 agaaaaaaat cttagcgtca cttttattaa gtacagtaat ggtttctcaa gtagctgttt
    38761 taacaactgc gcatgcagaa acgactgatg acaaaattgc tgctcaagat aataaaatta
    38821 gtaacttaac agcacaacaa caagaagccc aaaaacaagt tgaccaaatt caggagcaag
    38881 tatcagctat tcaagctgag cagtctaact tgcaagctga aaatgataga ttacaagcag
    38941 aatctaagaa actcgagggt gagattacag aactttctaa aaacattgtt tctcgtaacc
    39001 aatcgttgga aaaacaagct cgtagtgctc aaacaaatgg agccgtaact agctatatca
    39061 ataccattgt aaactcaaaa tcaattacag aagctatttc acgtgttgct gcaatgagtg
    39121 aaatcgtatc tgcaaacaac aaaatgttag aacaacaaaa ggcagataaa aaagctattt
    39181 ctgaaaaaca agtagcaaat aatgatgcta tcaatactgt aattgctaat caacaaaaat
    39241 tggctgatga tgctcaagca ttgactacga aacaggcaga actaaaagct gctgaattaa
    39301 gtcttgctgc tgagaaagcg acagctgaag gggaaaaagc aagtctatta gagcaaaaag
    39361 cagcagctga ggcagaggct cgtgcagctg cggtagcaga agcagcttat aaagaaaaac
    39421 gagctagcca acaacaatca gtacttgctt cagcaaacac taacttaaca gctcaagtgc
    39481 aagcagtatc tgaatctgca gcagcacctg tccgtgcaaa agttcgtcca acatacagta
    39541 caaacgcttc aagttatcca attggagaat gtacatgggg agtaaaaaca ttggcacctt
    39601 gggctggaga ctactggggt aatggagcac agtgggctac aagtgcagca gcagcaggtt
    39661 tccgtacagg ttcaacacct caagttggag caattgcatg ttggaatgat ggtggatatg
    39721 gtcacgtagc ggttgttaca gctgttgaat caacaacacg tatccaagta tcagaatcaa
    39781 attatgcagg taatcgtaca attggaaatc accgtggatg gttcaatcca acaacaactt
    39841 ctgaaggttt tgttacatat atttatgcag attaatttac agagggactc gaatagagcc
    39901 ctcttttcag gttttaccgt gacaatccct attaaaaatt atatcaaaat agcttgaaaa
    39961 tattggaaaa gtatggtaaa atgaaaattg tcgtgtgaac gataatactc attcttgatg
    40021 aattgtgaag cagttgccct tgggtcgttt tgcgagttga agtcaagaag aggaaaaaaa
    40081 caaaaaggag aaatactcat ggcagtaatt tcaatgaaac aacttcttga ggctggtgta
    40141 cactttggtc accaaactcg tcgctggaat cctaagatgg ctaagtacat ctttactgaa
    40201 cgtaacggaa tccacgttat cgacttgcaa caaactgtaa aatacgctga ccaagcatac
    40261 gacttcatgc gtgatgcagc agctaacgat gcagttgtat tgttcgttgg tactaagaaa
    40321 caagcagctg atgcagttgc tgaagaagca gtacgttcag gtcaatactt catcaaccac
    40381 cgttggttgg gtggaactct tacaaactgg ggaacaatcc aaaaacgtat cgctcgtttg
    40441 aaagaaatta aacgtatgga agaagatgga actttcgaag ttcttcctaa gaaagaagtt
    40501 gcacttctta acaaacaacg tgcgcgtctt gaaaaattct tgggtggtat cgaagatatg
    40561 cctcgtatcc cagatgtgat gtacgtagtt gacccacata aagagcaaat cgctgttaaa
    40621 gaagctaaaa aattgggaat cccagttgta gcgatggttg acaccaatac tgatccagat
    40681 gatatcgatg taatcatccc agctaacgat gacgctatcc gtgctgttaa attgatcaca
    40741 gctaaattgg ctgacgctat tatcgaagga cgtcaaggtg aggatgcagt agcagttgaa
    40801 gcagaatttg cagcttcaga aactcaagca gattcaattg aagaaatcgt tgaagttgta
    40861 gaaggtgaca acgcttaatt tatacaaata gtaattacct aggagggcgg ggcttagccc
    40921 ggctctccta ttttcaaaaa atataggaga attaaaatgg cagaaattac agctaaactt
    40981 gtaaaagagt tgcgtgaaaa atctggtgcc ggtgttatgg acgctaaaaa agcgcttgta
    41041 gaaacagacg gtgacatcga aaaagcgatt gaattgcttc gtgaaaaagg tatggctaag
    41101 gcagctaaga aagctgaccg tgttgctgca gaaggtttga ctggtgttta tgttaacggt
    41161 aatgttgcag cagttattga agtaaacgct gaaactgact tcgttgcaaa aaacgctcaa
    41221 ttcgttgaat tggtaaatac tacagctaaa gtcattgctg aaggaaaacc tgctaataat
    41281 gaagaagctc ttgctttgat aatgccttca ggtgaaactc ttgaagctgc atacgtatct
    41341 gcaacagcaa ctatcggaga gaaaatctca ttccgtcgct ttgcattgat tgaaaaaaca
    41401 gacgcacaac actttggagc ataccaacat aacggtggac gtatcggtgt tatttcagtt
    41461 gttgaaggtg gagacgaagc acttgctaaa caattgtcaa tgcacatcgc agcgatgaaa
    41521 ccaacagttc tttcttacaa agaattggat gagcaattcg ttaaagatga gttggcacaa
    41581 ttgaatcacg ttatcgacca agacaacgaa agccgtgcaa tggttaataa accagctctt
    41641 ccacacttga agtatggatc aaaagctcaa ttaactgatg atgttattgc tcaagctgaa
    41701 gctgacatca aagctgaatt ggctgcagaa ggcaaaccag aaaaaatctg ggacaaaatt
    41761 atcccaggta aaatggatcg cttcatgctt gataatacta aagttgacca agcttacaca
    41821 cttcttgcac aagtttacat catggatgac agcaagacag ttgaagcata ccttgaatca
    41881 gttaacgctt cggtagttga gtttgctcgc tttgaagttg gtgaaggtat cgagaaagct
    41941 gcaaacgact tcgaagctga agttgcagct acaatggcag cagccttgaa taactaataa
    42001 tagaaaggaa gcaatttgct tccttttttg tatagggctt atatttttcc tgaaattgtt
    42061 tttcccccag tctcactcga ttagaataat taaaacaaaa agccctataa taagggctaa
    42121 gtgcatttag gagactatac ttcaaattca tagtaagcgc gtcataacaa ggtatctatc
    42181 ctaattcccc aacttccagt atactagata aaaaataatt atcggaggaa aggtattgta
    42241 ctatgatgat tcaactaagt gatttaggtc aagttcacat tgtttgtggc aagacagata
    42301 tgagg
//
LOCUS       DAVHBD010000017        38246 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000017 DAVHBD010000000
VERSION     DAVHBD010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.017"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            444..740
                     /locus_tag="VVK04_000915"
     CDS             444..740
                     /locus_tag="VVK04_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU3989588.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            861..1805
                     /gene="manA"
                     /locus_tag="VVK04_000916"
     CDS             861..1805
                     /gene="manA"
                     /locus_tag="VVK04_000916"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU3989589.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1845..3180)
                     /locus_tag="VVK04_000917"
                     /pseudo
     CDS             complement(1845..3180)
                     /locus_tag="VVK04_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3408..4157
                     /locus_tag="VVK04_000918"
     CDS             3408..4157
                     /locus_tag="VVK04_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU3989590.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(4177..4632)
                     /locus_tag="VVK04_000919"
     CDS             complement(4177..4632)
                     /locus_tag="VVK04_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU3989591.1"
                     /translation="MNRREAVEFVNMCMIKNGDKILVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4652..5827)
                     /locus_tag="VVK04_000920"
     CDS             complement(4652..5827)
                     /locus_tag="VVK04_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU3989592.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5886..6731)
                     /locus_tag="VVK04_000921"
     CDS             complement(5886..6731)
                     /locus_tag="VVK04_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU3989593.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6856..7413
                     /locus_tag="VVK04_000922"
     CDS             6856..7413
                     /locus_tag="VVK04_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU3989594.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7432..7899
                     /locus_tag="VVK04_000923"
     CDS             7432..7899
                     /locus_tag="VVK04_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU3989595.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7988..8617
                     /gene="upp"
                     /locus_tag="VVK04_000924"
     CDS             7988..8617
                     /gene="upp"
                     /locus_tag="VVK04_000924"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU3989596.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8791..9381
                     /gene="clpP"
                     /locus_tag="VVK04_000925"
     CDS             8791..9381
                     /gene="clpP"
                     /locus_tag="VVK04_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU3989597.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9460..9708
                     /locus_tag="VVK04_000926"
     CDS             9460..9708
                     /locus_tag="VVK04_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU3989598.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVL
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9810..10970
                     /locus_tag="VVK04_000927"
     CDS             9810..10970
                     /locus_tag="VVK04_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU3989599.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            11238..12107
                     /locus_tag="VVK04_000928"
     CDS             11238..12107
                     /locus_tag="VVK04_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU3989600.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            12111..13067
                     /locus_tag="VVK04_000929"
     CDS             12111..13067
                     /locus_tag="VVK04_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU3989601.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            13067..13831
                     /locus_tag="VVK04_000930"
     CDS             13067..13831
                     /locus_tag="VVK04_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989602.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13831..14541
                     /locus_tag="VVK04_000931"
     CDS             13831..14541
                     /locus_tag="VVK04_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989603.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14900..15556
                     /locus_tag="VVK04_000932"
     CDS             14900..15556
                     /locus_tag="VVK04_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU3989604.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15664..16759
                     /gene="prfB"
                     /locus_tag="VVK04_000933"
     CDS             join(15664..15735,15737..16759)
                     /gene="prfB"
                     /locus_tag="VVK04_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU3989605.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16777..17469
                     /gene="ftsE"
                     /locus_tag="VVK04_000934"
     CDS             16777..17469
                     /gene="ftsE"
                     /locus_tag="VVK04_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU3989606.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17462..18388
                     /locus_tag="VVK04_000935"
     CDS             17462..18388
                     /locus_tag="VVK04_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989607.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18674..20854
                     /locus_tag="VVK04_000936"
     CDS             18674..20854
                     /locus_tag="VVK04_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU3989608.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20906..21721
                     /locus_tag="VVK04_000937"
     CDS             20906..21721
                     /locus_tag="VVK04_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU3989609.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21861..23204
                     /locus_tag="VVK04_000938"
     CDS             21861..23204
                     /locus_tag="VVK04_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU3989610.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLIKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23581..24771
                     /locus_tag="VVK04_000939"
     CDS             23581..24771
                     /locus_tag="VVK04_000939"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU3989611.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            25324..26259
                     /locus_tag="VVK04_000940"
     CDS             25324..26259
                     /locus_tag="VVK04_000940"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU3989612.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            26293..27330
                     /locus_tag="VVK04_000941"
     CDS             26293..27330
                     /locus_tag="VVK04_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU3989613.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLADDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27503..28108
                     /locus_tag="VVK04_000942"
     CDS             27503..28108
                     /locus_tag="VVK04_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU3989614.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            28265..28795
                     /locus_tag="VVK04_000943"
     CDS             28265..28795
                     /locus_tag="VVK04_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU3989615.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28816..29901
                     /gene="rlmN"
                     /locus_tag="VVK04_000944"
     CDS             28816..29901
                     /gene="rlmN"
                     /locus_tag="VVK04_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU3989616.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNHRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            29901..30383
                     /locus_tag="VVK04_000945"
     CDS             29901..30383
                     /locus_tag="VVK04_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU3989617.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            30385..31926
                     /locus_tag="VVK04_000946"
     CDS             30385..31926
                     /locus_tag="VVK04_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU3989618.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31982..32785)
                     /locus_tag="VVK04_000947"
     CDS             complement(31982..32785)
                     /locus_tag="VVK04_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU3989619.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32869..33081)
                     /locus_tag="VVK04_000948"
     CDS             complement(32869..33081)
                     /locus_tag="VVK04_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989620.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(33560..33769)
                     /locus_tag="VVK04_000949"
     CDS             complement(33560..33769)
                     /locus_tag="VVK04_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989621.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33939..34211
                     /gene="rpsP"
                     /locus_tag="VVK04_000950"
     CDS             33939..34211
                     /gene="rpsP"
                     /locus_tag="VVK04_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU3989622.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            34231..34470
                     /locus_tag="VVK04_000951"
     CDS             34231..34470
                     /locus_tag="VVK04_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU3989623.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34700..34943
                     /locus_tag="VVK04_000952"
                     /pseudo
     CDS             34700..34943
                     /locus_tag="VVK04_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            35047..35835
                     /locus_tag="VVK04_000953"
     CDS             35047..35835
                     /locus_tag="VVK04_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU3989624.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            35866..36384
                     /gene="rimM"
                     /locus_tag="VVK04_000954"
     CDS             35866..36384
                     /gene="rimM"
                     /locus_tag="VVK04_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU3989625.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            36374..37093
                     /gene="trmD"
                     /locus_tag="VVK04_000955"
     CDS             36374..37093
                     /gene="trmD"
                     /locus_tag="VVK04_000955"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU3989626.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            37105..37443
                     /locus_tag="VVK04_000956"
     CDS             37105..37443
                     /locus_tag="VVK04_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989627.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(37473..37793)
                     /locus_tag="VVK04_000957"
     CDS             complement(37473..37793)
                     /locus_tag="VVK04_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989628.1"
                     /translation="MIHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37891..38106
                     /locus_tag="VVK04_000958"
     CDS             37891..38106
                     /locus_tag="VVK04_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU3989629.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(38103..>38246)
                     /locus_tag="VVK04_000959"
     CDS             complement(38103..>38246)
                     /locus_tag="VVK04_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989630.1"
                     /translation="KIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKAKLTRFEEIF
                     EEY"
BASE COUNT        11702 a         7039 c         8291 g        11214 t
ORIGIN      
        1 catttcgcca aatcgttgtt tgattacagt ctatagtgta ttgaatctat aacagtacac
       61 cttggctgct aaaatatttc tataaattaa tttgactttc ctgatagagt tgttcacatc
      121 ttatttcaaa ccactataaa agttctataa tctctttata agatttgccc atcagacgaa
      181 atataatgga ttgaaactag aatagtacac ctctgcttct aaaacattgt tagaaatcaa
      241 tttgactgtc ctgattgatt tgtcctattc ttgtttcatt ttaatataga atgatttgaa
      301 ggcatttatg atatttagct gtacgagagt cttttaaaag tgttttgatg gtttggattt
      361 cttctttagt tgatttcata tcactattat ataatgcttt ttgattttag tttagtatta
      421 tcgtagaaaa tggactcggt gctatggata caccggatga gaatggttat gtagcagata
      481 actatcggat tacttactta gaggcccaca tcaaggccat gcgagatgcc atttaccaag
      541 acggggttga cttgcttggt tatacgactt ggggctgtat cgatccggtt tcagctggca
      601 caggggaaat gaataagcgc tatggcttta tctatgtaga tcgagataat gtaggaaacg
      661 gagctctcaa acgtagcaag aagaagtcct tctattggta caaggatgtc attgatagca
      721 atggtgcaag catcgggtag agcacatttg tttactattt ttataaaatc ttctccctgc
      781 tttataagat gtaaaaaaga gttcaattcg aactcttttt ttgctataat gaggggagaa
      841 aaatcagaca ggagatcgac atgtcagaac cattattttt acaatcagtt atgcaagaaa
      901 aaatctgggg tggagccaag ctacgtgatg agtttggcta cgacatccca agtgaaaaag
      961 ttggagaata ctgggctatc tcagctcatc taaatggtgt ttctaaagtt gccaatggtc
     1021 gttacgaggg aacagatctt gctactttgt atgcggaaca ccgtgaattg tttggcaatc
     1081 gtcctgagcc tgtatttccg cttttgacta agattctgga tgctaacgac tggctcagcg
     1141 ttcaagttca cccagacgat gcttatggac tagagcatga aggcgaactt ggaaaaacag
     1201 aatgctggta catcatcgct gcggatgaag gttcagagat tatctacggt cacaatgcca
     1261 agtcaaaaga agaactccgc cagcaaatcg aggacaagaa ctgggatgac ttgttgacca
     1321 aagtccctgt taaggctgga gatttcttct atgtaccaag cgggactatg cacgctatcg
     1381 gggcgggtat cttaatcctt gaaacccagc agtctagcga taccacctat cgcgtctatg
     1441 actttgaccg caaggatgac aaaggcaact tgcgtgaact tcaccttgaa aaatccatcg
     1501 atgtcttgaa cattggtgag ccagcaaata gccgtcctgt aactgttaaa gcagatgatt
     1561 tgcgttccac tctccttgta tctaatgatt tcttcgcagt ttacaagtgg gaaattactg
     1621 gaaaagttga ctttgaaaag acagctgact acagcttatt gagtgtctta gctggtcaag
     1681 gtcagctaac tgttgacggg aaaaattatc caattcaaaa aggcagccac tttatcctac
     1741 caagtgatgt tgaagcttgg actctggaag ggcaaggttt ggaattgatt gttagccatc
     1801 cataaaaaga aagggcctga gttcactact caagtccttt ttgattacat aaattgggca
     1861 atgaagacca caatgatgat gattggaatg acgaaacgaa gaaacgaaga aggaagagcc
     1921 agacttggaa cagtccttgt ttccatgctc tttcatcgag atggagttcc tccattgcaa
     1981 gagccttttt aaagatatag cctgtaaaaa gtgaaaggta gagagttcca aatggcatga
     2041 ggagattgga aaccaagaag tccatagcgt caaagaaggt cttaccaaaa atgtgaacat
     2101 ccgccatgac accgtaagat agggctgaag gaatgccaaa gacaaaggtc aaaattccta
     2161 aaataacact ccatttagca cgcttgctgt tgtcctgatt ggtgatattg tctacattga
     2221 tttccagcat cacgacagaa gaagtgacag tcgcaaagag gaagaggacg tagaaaatgg
     2281 ttccaaaagg catcttgtca aagagttgag gcaagacgat aaagagcagg ctgggtcccc
     2341 cttcagactg gatattgaag gctgacatgg ctgggaaaat ggctagacct gccatgatgg
     2401 atatcgagat attcatggct acgatggaga ttcctgactg gactagattg gttttcttgt
     2461 ccaagtaaga agcataggtc aacatgactg taacccctag tgagagggca aagaaagatt
     2521 gtcccagagc atagaggaga tcagcgctag tcagttttga aaagtctggt ttgaggaagt
     2581 aaagaacccc ttccatggca tttgacaagc tgagagagtg accgatgata acaacaaaga
     2641 tgataaagag caggggcatc atgactttcg aagctctttc aatccctttt tgaaccccac
     2701 gtgatacaat gaagatattc aataggataa aggccgcttg agctcctagg gcaatggctg
     2761 gatttgaaat gattgaagta aataactgag cataatcacc cgttccacca agttggaaca
     2821 atttcccaaa ctcaatacct agatagacta gaatccatcc tccgataaca ctgtaaaaag
     2881 ataagaggat aaagagggca aaggcgccaa tccaaccgat aaagttgtac ttgttattct
     2941 tgcccagttt tccaaaggtt ttgatagcgg aaacgccagc actacggcca agggcaaact
     3001 cagccagcag gagagggaaa ccgattaaaa tagtggaaat gagaaagatt agtaaaaagc
     3061 ctccatcgcc attagcagca gtcatgtagg gaaacttcca aacggaacca agcccgatgg
     3121 ccagccagca gatgctagaa taaaaccaag tttcgacccc cattgtgatt tttctgacat
     3181 agttaaactc tgatctcctt tttcaaaata agaaaaagct acttgagttg tcaaatagcc
     3241 ttctgtttga ttgatagact tgactatcct atcatgtttt ctaaggtctg tcaagaaaat
     3301 cattttcaag ttttcacacc tttctcaaaa aagttaaaaa attttctcaa aaacgcttga
     3361 ctctgaccta aggggagggg ttatactatc attgtaagga ggaaatcatg taccatataa
     3421 aagaagctgc gcagctttca ggtgtctctg tcaagaccct gcatcactat gacaagatag
     3481 gactcttggt ccccttaaag tcggaaaacg gctatcgaac ctacagtcaa gaggatttgg
     3541 aacgccttca ggtcattctt tactacaaat atctaggctt ttctttagag aaaatagcag
     3601 agctgttaaa ggaagaaagg acagatttat tgccccattt gactaggcag ttggactatc
     3661 taactcgcga aaggcaacat ctggatacct tgatttccac cttgcaaaaa actattcaag
     3721 aacaaaaagg agaaagaaaa atgaccattg aggaaaaatt cacgggattt agctatcaag
     3781 acaatcaaaa ataccaccaa gaagcggtag agaaatatgg tcaagaagtc atgggacaag
     3841 cgctcgaacg ccaaaaaggt cacgaagacg aggctacggc cgcctttaac caagtctttc
     3901 aaactttggc acaaaatctt caagttggtt tacctgcaac agcaaccgaa aaccaagagc
     3961 aagcagccaa gctcttgcaa gccattcgca cttatggatt tgactgctct attgaggtat
     4021 tcggtcatat cggtaaaggt tacgtctaca acccagagtt taaggaaaac attgacaagt
     4081 ttggttctgg aacagcccag tacacgtcag atgccattgc agcttacgtt cagacaaatg
     4141 cagaaaaaat aggctaggaa tttcctagcc tattttttac ttcaaatcat aaagccagtc
     4201 gtcaccgttt ttgtagtaaa agaattcact gagatcttct tctagaaaca cacgaagcat
     4261 atcagacata tcatcggttg caagttttag atgagaaaga ttttcaaagt cctcccacca
     4321 aactttccct tcgtctgaag actggagttc accagtaaag tgttctgtct tgtaaaaaag
     4381 gacgacataa cgataatcct tgtcgtcata ccagtttttg ataccacaga gttggggttt
     4441 ggaaatgatc agaccagttt cttctttcac ttcacgaatg acagcatcga caaaggattc
     4501 gccacgttca acatgaccac caggaaaagt aatgccaggc cagtcgggac taactcggtc
     4561 ttggaccagg atcttatctc cgtttttaat catacacatg ttaacaaatt cgactgcctc
     4621 tcttctgttc attcttcaca acctttaatc tttaatcata atgcagactt cccgccaccc
     4681 agccggtaca gagggcagaa gtgatgttaa agccacccgt gtgggcattg atatccataa
     4741 cttcgcctgc aaagtggagg ccaggtacca gcttactttc aagggtttta ggattgattt
     4801 ccttgagact gactccaccc ttggtaacaa aggactttgc aagggacatt tttccagtta
     4861 caggaatttt aagttcttta atggactgga caagttgttc tcgttccttt tcagtcagct
     4921 gtttgacttt ttcaggatat ccttgtacaa aaaattcggc caagcgttct ggtaacaagg
     4981 tttttaaagc gtttttcaag gatttttccc gattttcttc tagaaatgta accaagtcct
     5041 tctcagaaag ttgaggcaaa acatcgagtg agagaacctc cccacctttg acaaagctag
     5101 acatgcgtag ggcagcagga cctgacaaac caaagtgggt aaagagtaaa tcatgagtga
     5161 tgacatgctt accataactt agggtcacat cgtccagaga aatcccttgt aaggctttat
     5221 gtggaaaatc tgttaataaa ggactttcag cagcctcaag atcggtgatg gtatgcttaa
     5281 aatggcgagc aatctcgtga ccaaaaccag tcgaaccagt cgaaggataa gacttaccac
     5341 ctgttgtgac aatgagtttc tcacaagtga aggtttgatc cgctgactta aggacaaact
     5401 ggtcatctac ttttttaaca gaaacgattt ctatttgagt agcaacttga ccacctagtt
     5461 cggtgatttt cttttccaaa gcttcgataa tagtccgaga cttgtcactg gctggaaaga
     5521 cgcgtccgtg gtcttcgacc ttaagtttaa caccattttc tgtaaaaaag ttgatgatgt
     5581 catgattatc gaactgggag aaaacactgt aaagaaagcg tccgtttcca ggaattccag
     5641 ctagcaggtt gtctaagcta ccattgttgg tcacattgca acgtccccca ccagtcccag
     5701 ctaatttttt tccaagtttc cgattttttt cgatgaggag ggttttctgt ccataaaagc
     5761 tactggaaat cgtagccatc ataccagcag gtcccccacc gatgacaata gtatcaaaat
     5821 gtttcatagc tctattgtac cacaaaaaaa caagagatga tggtcacctc ttgtcaagaa
     5881 tgcaattaat caatttcata gcccatcagc aaaccgccct cttctgcata gaaactgcag
     5941 agaccagagg ttggtagaat tttaatatcc gcttgtggga aggtttcacg gattcgctct
     6001 gagagctgtt gacaacattt ttcgttattg cgttgggcca tgacaatacg gccaccagca
     6061 tatccagctt ttactaactc atcataggca gcttgaactg atttctttga tccccttgct
     6121 ttttgtagca attcgagagt tccagtttca ctagcttttc cgaccatacg aatgttgaga
     6181 aggccaacga ccgtaccgat aagcttgctc aaacggccgt tcttcaccaa gttatcgact
     6241 ttggctagga caaagagcaa cttagttttt tcttgatagg cagtgatagc ttcaaccact
     6301 tcttcaaaag acaagccctg gtcaatcaag tcattcaatt tttctacgag taggtcaact
     6361 tcaccaccag cagataaact atcaatcaca tgaatcttag tgtcaggatg gtcttctaga
     6421 taaatattct ttgctagttg agcactattg tgactgccag aaagggtacc tgtgatggtt
     6481 actaggaaaa tgtttttggc accttcaaat gctcgcaaat agtcatctgg gcttggacaa
     6541 gccgattttg aagcttctgc agttgcatac atggtttcca tcatttggtc aatatcgaga
     6601 ctggcgtcat caacaaagac ctgatcagct acttgaatgg ttaaggggac acttacaaag
     6661 gttgtgttaa tagctggtgt tggcagttga cgataatcac aaccagagtc agcaataatt
     6721 ttccaagtca tagaaattct ccatctttgt cagttataca ttgacaaagg ttctgtcttt
     6781 ttttacaatt atatcatgaa aacccttgaa acaaaagcat catccgtctg ttgtgacaag
     6841 tagaaagaaa atgttatgtc tgaacgtaga atctctgaaa agtctcttga aaatctcaga
     6901 aaatcaaacc aagaatccaa tttattaacc agagaagcca ttgaaacagc cctcttgcaa
     6961 ctcttggaaa aaaaggagct gaccaagatt agtatttctg aattggtcaa acgtgcaggt
     7021 gtttcgcgtg cggcctttta tcgcaattat gactccaaag aggaaatttt agagagcgtc
     7081 tttaaacgaa ctgtccacaa tattatggaa cagctgcatc attacgattt aaagacagat
     7141 ctttatttgg tttgggttca ccttttccgg gaggccagaa aggaagctag agtgattcaa
     7201 ttggccttgg attaccatct ggaaaaaatc tttgtccaag ccatgcagga atttctagaa
     7261 aaataccacg ggaaatcaaa aggtgtcagc tcttatcttc attccttctg gagctcagcc
     7321 atcgtctctg tccttctaaa atggatcaag gatggcatga aggtaccagc tgaaaagatt
     7381 gcagatttag gtttaccatt ttttaaaaaa tagagaaaaa ggagaaaaga gatgactgaa
     7441 aaaagactgg cctgggatga gtattttgca gcccaagccc tactaattgc gaatcgttcc
     7501 acttgtaaac gtgctaaagt gggcgcgatt ctggtaaaag ataataaggt tatttccact
     7561 ggttacaatg gttcggtgtc agggactgag cattgtattg atcacgaatg tttggtcatt
     7621 gaaggccact gtgttcgcac ccttcacgct gaggtcaatg ctatccttca aggtgctgag
     7681 cgtggtgttc ccaaaggctt tacagcctat gtaacccatt ttccttgtct caactgtaca
     7741 aaacaattgc ttcaggtcgg ctgcaagcgc gtggtttata tcaaccagta ccgaatggac
     7801 gactacgccc aataccttta tcaagaaaaa gggacagaat tgacccattt accacttgag
     7861 acagtacaga cagctcttaa agaggctgat ctaatgtaaa aattatcaaa aataaatggc
     7921 ttagaaagat ttttaaaccg ttttttggta taataagaag aataaattga aagaaggaat
     7981 tccaaaaatg ggaaaaattg aagttattaa tcacccactg attcaacaca aattgtcaat
     8041 cttgcgtcgt acagatactt ctacaaaagc ttttcgtgag ctagtagatg agattgcaat
     8101 gttgatgggg tatgaagtac ttcgtgatct tccactagaa gatgtggaaa tcgaaacacc
     8161 aattacaaaa acagttcaaa aacaattggc aggtaagaaa ttggccatcg tcccaatctt
     8221 gcgtgcaggt atcgggatgg ttgatggtct cttgagcttg gttccagctg ctaaagttgg
     8281 ccacatcggt atgtaccgtg atgaagaaac acttcaacca gttgaatact tggtgaaatt
     8341 gcctgaggac attgaccaac gtcaaatttt tatagtagac ccaatgttgg caacaggtgg
     8401 ctcagcaatc ttggctgttg attctcttaa aaaacgtggc gcatcaaata tcaaatttgt
     8461 ctgccttgta tctgctccag agggtgtaaa agcccttcaa gaagctcatc cagatgtaga
     8521 aatctttaca gcagccttgg atgaacgttt gaacgaacac ggttatatcg ttccaggtct
     8581 tggagatgct ggagaccgct tgttcggtac aaaataagat cgaaaagaag aatgacttgg
     8641 aaaagtattt ccagtcacga aaggaggttg ggtttttgtt tctgtctaat gaaagcagag
     8701 caaaaatttg accttttttg accaagatat tataatagtc ttatcttcag tcatttgacc
     8761 aacaaaatta aaactcaaaa ggagaaatga atgattcctg tagttattga acaaacaagc
     8821 cgtggagaac gttcttacga tatttactca cgtcttctca aagaccgcat cattatgctg
     8881 acaggtccgg ttgaagacaa tatggctaac tctgttattg cccaactgct tttcttggat
     8941 gcccaagata gtacaaaaga tatttacctt tatgtcaata caccaggtgg ttctgtttca
     9001 gctggtttgg caatcgtaga taccatgaac tttatcaagg cagatgtcca aaccattgtt
     9061 atgggaatgg ctgcatctat gggaacagtc atcgcatcaa gtggagcaaa aggcaaacgt
     9121 ttcatgcttc caaatgctga atacatgatt caccaaccaa tgggcggtac aggtggtggt
     9181 acccaacaaa ctgatatggc tatcgctgca gaacacttgc tcaaaactcg taataccttg
     9241 gaaaaaatct tggctgaaaa ttcaggtcag tcaatggaaa aagtccatgc agatgcagaa
     9301 cgtgataact ggatgagcgc ccaggaaaca cttgaatatg gctttattga tgaaattatg
     9361 gccaacaatt cattgaacta atgatgatag aaggcaaact cgactgggtt tgcttttttt
     9421 ggtataatag ggagagattt cttagaaaga ggatttatca tgtttgaaaa agtcaatcgc
     9481 tctggcttga ttatctatct ttactataat cgtgatgcca aaaaactgca ggattatgga
     9541 gatattacct atcattccaa gaaacatcgt tacttacaac tctatgttct aactcaagaa
     9601 gtggagcaat tggtcggacg cttgagcaag gaaaaattta ttaaaaaagt tagggtttgt
     9661 catatccaag agttggaaac accctttgtg ggcaatcttt atcgatagga aaacgttatc
     9721 atcgaaaaag ttcaaggaaa acattgacaa ttttctgata attcggtata ttcttaacag
     9781 actatttaag aaataaggag acaaaaaaga tgaagaaaaa atttgcccta tcgtttgtgg
     9841 cgcttgcaag tgtagcactt cttgcagcct gtggagaagt gaagtctgga gcagtcaaca
     9901 ctgctggtaa ctcagtagag gaaaagacaa ttaaaatcgg gtttaacttt gaagaatcag
     9961 gttctttagc tgcatacgga acagctgaac aaaaaggtgc ccaattggct gttgatgaaa
    10021 tcaatgccgc aggtggtatc gatggaaaac aaatcgaagt agtcgataaa gataataagt
    10081 ctgaaacagc tgaggctgct tcagttacaa ctaaccttgt aacccaatct aaagtatcag
    10141 cagtcgtagg acctgcgaca tctggtgcga ctgcagctgc ggtagcgaat gctacaaaag
    10201 caggtgttcc attgatctca ccaagtgcga ctcaagatgg attgactaaa ggtcaagatt
    10261 acctctttat tggaactttc caagatagct tccaaggaaa aattatctca aactatgttt
    10321 ctgaaaaatt aaatgctaag aaagttgttc tttacactga caatgccagt gactatgcta
    10381 aagggattgc caaatctttc cgcgagtcat acaagggtga aatcgttgca gatgaaactt
    10441 tcgtagcagg tgacacagac ttccaagcag cccttacaaa aatgaaaggg aaagactttg
    10501 atgctatcgt tgttcctggt tactataatg aggctggtaa gattgtaaac caagcgcgtg
    10561 gtatgggaat tgacaaacca atcgttggtg gtgatggatt caacggtgag gagtttgtac
    10621 aacaagcaac tgctgaaaaa gcatcaaaca tctactttat ctcaggcttc tcaactactg
    10681 tagaagtttc agctaaagct aaagccttcc ttgacgctta ccgtgctaag tacaatgaag
    10741 agccttcaac atttgcagcc ttggcttatg attcagttca ccttgtagca aacgcagcaa
    10801 aaggtgctaa aaattcaggt gaaatcaaga ataaccttgc taaaacaaaa gattttgaag
    10861 gtgtaactgg tcaaacaagc ttcgatgcag accacaacac agtcaaaact gcttacatga
    10921 tgaccatgaa caatggtaaa gttgaagcag cagaagttgt aaaaccataa tagaaaaatg
    10981 ttgaaatagg gaatgagcct ttgactcact ccctgtttcg atatttaata ctcttcgaaa
    11041 atctcttcaa actgcgtcaa cgtcgccttg gattatatat gtgactgact tcgtcagtct
    11101 tatctacaac ctcaaagcag tgctttgagc aacctgcggc tagtttccta gtttgctctt
    11161 tgattttcat tgagtataag aacctatcaa aaagtgaggg aaaaccctcg gaattataaa
    11221 tagaaagagt gaatcttatg ctccaacaac tcgtaaatgg tttgattcta ggtagtgttt
    11281 acgcgctgtt agccctagga tataccatgg tttacggaat tatcaagctc atcaacttcg
    11341 cccatggtga tatttatatg atgggagcct ttatcggtta tttcttgatc aattctttcc
    11401 aaatgaattt ctttgtagcg cttattgtag ctatgctagc gacagctatt cttggtgtcg
    11461 tgattgagtt tcttgcttac cgacctttgc gccactctac tcgtattgct gttttgatta
    11521 cggctattgg ggtttctttc ctattggagt atggaatggt ctatctggtt ggtgccaata
    11581 cccgtgcctt ccctcaagcg attcaaacag ttcgatatga tttgggacca attagcttaa
    11641 caaatgtgca gttaatgatt ttgggcattt ccttgatttt gatgattttg ttacaagtca
    11701 ttgtccaaaa gactaagatg gggaaagcca tgcgtgcagt atcagtagat agcgacgcgg
    11761 cgcaattgat ggggatcaat gtaaaccgta cgattagctt taccttcgct ttgggttctg
    11821 ctcttgcggg tgcggctggt gttctgattg ctctttatta taactctctt gagcctttga
    11881 tgggggttac tccaggtctt aaatctttcg ttgccgcagt acttggtggt atcggaatta
    11941 ttcctggtgc tgctcttggt ggctttgtga ttggtctatt ggaaaccttt gcgacagcct
    12001 ttgggatgtc agatttccgt gatgccattg tttatggaat cttgttgttg atcttgattg
    12061 tccgcccagc tggtatcctt ggtaagaatg tgaaagagaa ggtgtaaacg atgaaggaaa
    12121 atttaaaagt taatattcta tggttactcc ttttgttagc tggctatagc ttgattagtg
    12181 tactggtttc agtcggagta cttaatctat tctatgtaca gattttacaa caaattggaa
    12241 ttaatattat tttggctgtt ggtctcaact taatcgttgg tttttcagga caattttcac
    12301 ttggtcatgc tggtttcatg gcgattggtg cctatgcagc agctattatt ggttctaaat
    12361 caccaaccta cggtgccttc tttggagcta tgcttgtagg ggctttgctt tcaggagcag
    12421 ttgccttact tgtcggcatt ccaaccttgc gcttgaaggg ggactatctt gcggtagcaa
    12481 ctctgggtgt ttctgaaatt atccgtatct ttatcatcaa tggtggaagt cttacaaatg
    12541 gtgcggcagg tatcttaggg attcctaact ttacaacttg gcaaatggtt tacttctttg
    12601 tcgtgattac aaccattgca accttgaact tcttgcgtag cccaattggc cgttcaaccc
    12661 tctctgttcg tgaagatgaa atcgctgctg agtcagttgg ggttaatacg actaaaatta
    12721 aaatcatcgc ttttgtcttt ggtgccatta ctgcaagtat tgctgggtca cttcaggcag
    12781 gatttatcgg gtctgttgta ccgaaagatt acaccttcat caactcaatc aacgttttga
    12841 ttattgttgt atttggtgga ctcggttcca ttacaggtgc gattgtttcg gctattgttc
    12901 tgggaatttt gaatatgctt ctccaagatg ttgctagtgt gcgtatgatt atttacgctt
    12961 tggccttggt attggtaatg attttcagac caggtggact ccttggaacg tgggaactga
    13021 gcctatcacg tttctttaaa aaatctaaga aggaggaaca aaactaatgg cattacttga
    13081 agtaaaacag ttaaccaaac attttggtgg tctaacagct gttggagatg tgactcttga
    13141 attgaacgaa ggggaactgg ttggattaat cggtccaaac ggagctggga aaaccaccct
    13201 tttcaacctt ttgaccggtg tttatgaacc aagcgaggga acagtaaccc tagatggtca
    13261 ccttttgaat gggaaatcac cttataagat tgcctctttg ggacttggac gtactttcca
    13321 aaatatccgt ctctttaaag atttaacagt tttagacaat gttttgattg cttttggaaa
    13381 ccatcacaaa cagcatgttt ttactagttt cttacgctta ccagcttttt acaagagtga
    13441 aaaagaatta aaggctaaag ctttggaatt gttgaaaatc tttgatttag atggtgatgc
    13501 agagactctt gctaaaaatc tttcctacgg acaacaacgt cgtttggaaa ttgttcgtgc
    13561 ccttgctacg gaacctaaaa ttctcttctt agatgaacca gcagcaggta tgaacccaca
    13621 ggaaacagcc gaattgactg agttaattcg tcggatcaaa gatgaattta agattacaat
    13681 catgttgatt gaacacgata tgaatctggt catggaagta acagaacgta tctacgtact
    13741 tgaatatggc cgtttaattg ctcaaggaac tccagacgaa attaagacca ataaacgcgt
    13801 tatcgaagct tatctaggag gtgaagccta atgtctatgt taaaagttga aaatctttct
    13861 gtgcattacg gtatgatcca agcagtccgt gatgtaagct ttgaagttaa tgaaggagaa
    13921 gttgtttccc ttatcggtgc caacggtgca ggtaagacaa ctattcttcg caccttgtca
    13981 ggtttggttc gaccaagttc aggaaagatt gaatttttag gtcaagaaat ccaaaaaatg
    14041 ccagctcaga aaatcgtggc aggtggcctt tcacaagttc cagaaggacg ccacgtcttt
    14101 cctggcttga ctgttatgga aaatcttgaa atgggagctt tcttaaagaa aaatcgtgaa
    14161 gaaaatcaag ctaacttgaa gaaggttttc tcacgctttc ctcgtcttga agaacggaag
    14221 aaccaagatg cagctactct ttcaggaggg gaacaacaaa tgcttgccat gggacgcgct
    14281 cttatgtcaa caccaaaact tcttctttta gatgaaccat caatgggact tgccccaatc
    14341 ttcatccaag agatttttga tatcattcaa gatattcaga agcaaggaac aaccgtcctc
    14401 ttgattgaac aaaatgccaa taaagcactt gcaatctctg accgaggata tgtattggaa
    14461 acaggaaaaa tcgtcctatc aggaacagga aaagaactcg cttcatcaga agaagtcaga
    14521 aaagcatatc taggtggcta aaacaatcca gtggattgtt ttagtcggca gatgaagatt
    14581 acgaagtaat catcaatata gtccgggggc cctttttagt cggtggatga agattgcgaa
    14641 gcaatcatca aatccagagg attgttttag ccggtagatt gagattgcaa acaaatctgc
    14701 atctacattg aaagcttaat ttctaataat tgaaaaaatc gaatgaaaag tttcttacct
    14761 tcattcacag agctcgattt tagagctctt tttgctagct tattcatact tttctaaatt
    14821 ttgaaaaaga aatgtaagcg tttgatagat ttgcaaaaag attgtataat agggataaga
    14881 atagaaaagg agaagtctca tggcagttaa agattttatg acccgcaagg tagtttatat
    14941 tagtccagat acaacagtat ctcatgcagc agatttgatg agagagcaag aattgcatcg
    15001 cttgcctgtt atcgaaaatg atcaattggt tggtttggtg actgagggaa ccattgcaca
    15061 agcaagtcca tctaaagcaa caagtctttc tatctatgag atgaattatc ttctgaataa
    15121 gacaaaagta aaagatgtca tgattcgcga tgttgtcact gtctcaggct atgctagtct
    15181 agaagatgca acttatctga tgttgaaaaa taagattggt attctccctg tcgtagataa
    15241 ccatcaagta tacggagtta ttactgaccg tgacgttttc caagcctttc ttgaaattgc
    15301 aggttatggc gaagaaggga ttcgtgtacg ctttgttaca gaagatgaag ttggtgttct
    15361 tggaaaaatt atttctttga ttgtagaaga aaatttgaat atatcccata cagtcaatat
    15421 tccgcgtaag gatggtaagg tcattatcga agtgcaaatc gatggatcaa ttgatttacc
    15481 agccttgaaa gaaaaatttg aagcaaatgg tattcaagtg gaagaaatcg ctcgcacttc
    15541 agcaaaagtc ttgtaagaag ggaagcccaa aggcttcttt tttcatgaaa aggggattag
    15601 agcaaaagat ggaaagaaat gataaaatat gctataatga aatgatgtaa aaaaggagta
    15661 tttatggaca tttcagtaat tcgtcagaaa attgacgcaa atcgtgaaaa attagcttct
    15721 ttcagggggt ctctttgacc tcgaagggct agaggaagag attgccatct tggaaaacaa
    15781 gatgacagaa cctgattttt ggaacgataa tattgcggcc caaaaaacgt cgcaagaatt
    15841 gaatgaatta aaaaacactt acaatacctt ccataagatg gaagagttgc aggatgaagt
    15901 cgaaatttta ttggattttt tggctgaaga cgagtcagtg catgatgaac tggtagcgca
    15961 gttagccgaa cttgataaga taatgaccag ctacgagatg actctactct tgtcagaacc
    16021 ttatgaccac aacaatgcca tcttggaaat ccatccaggt tctggtggta ctgaggcgca
    16081 ggactggggt gatatgttgc ttcgtatgta tactcgttat ggtaatgcta aaggctttaa
    16141 agtggaagtg ttggattacc aagcaggtga tgaggctggt attaagtcgg taactttatc
    16201 atttgaaggg cctaatgcct atggtctcct caagtcagaa atgggtgttc atcgcttagt
    16261 gcgaatctca ccatttgact ctgccaaacg tcgccatacc tctttcacat ctgtagaagt
    16321 gatgccagaa ttggatgata ctattgaagt ggaaatccgt gaagatgata tcaagatgga
    16381 taccttccgt tcaggtggtg ccggtggaca aaacgtcaat aaggtttcaa caggtgtacg
    16441 tttaacccac attccaactg gaattgttgt ccaatcaaca gtggatcgta cccagtatgg
    16501 aaatagagat cgcgccatga agatgttgca ggctaagctc tatcaaatgg agcaagagaa
    16561 gaaggctgcg gaggtagatt ctctcaaagg tgagaaaaag gagatcactt ggggaagtca
    16621 aatccgttct tatgtcttca cgccttatac tatggtaaaa gatcaccgaa ctagctatga
    16681 ggttgctcag gtagataagg ttatggatgg ggacctagat ggttttatcg atgcttatct
    16741 caagtggcga attagctaag atagaaagga actcacatgt caattattga aatgagagat
    16801 gtcgttaaaa aatacgacaa cggaacgact gctctacgcg gtgtttcggt tagcgttcaa
    16861 ccgggggaat ttgcttacat cgtaggacct tcaggagcag ggaagtcaac ttttattcgt
    16921 tctctgtatc gtgaagtaaa aatcgataaa ggaagtctat cagttgctgg ttttaatctg
    16981 gttaagatca aaaagaaaga tgtcccgctt ctacgtcgta gtgttggggt tgtcttccag
    17041 gattataaac tgttaccaaa gaaaactgtc tatgaaaata ttgcttacgc tatggaagta
    17101 atcggggaaa atcgccgtaa tatcaaaaga cgagtgatgg aagttttgga cttggttgga
    17161 ttgaagcata aggttcgttc tttcccaaat gaactctcag gtggggagca acagcggatt
    17221 gcgattgcgc gtgcaattgt aaataatccc aaagtattga tagctgatga gccaacagga
    17281 aatctggatc cggataattc atgggaaatt atgaatctct tggaacggat taacctacaa
    17341 ggaacaacta ttttgatggc gactcataat agccagattg taaatacctt gcgccaccgt
    17401 gtcattgcca ttgaaaatgg ccgtgtcgtt cgtgacgaat caaaaggaga gtatggatac
    17461 gatgattagt agattttttc gccatttatt tgaagcctta aaaagtttga aacgaaatgg
    17521 ttggatgaca gtagctgctg tcagttcagt catgattact ttgaccttgg tggcaatatt
    17581 tgcatctgtt attttcaata cagcgaaact agctacagat attgaaaata atgtccgtgt
    17641 agtagtttat atccgaaagg atgtggaaga taatagtcag acaattgaaa aagaaggtca
    17701 aactgttaca aataatgact accacaaggt atatgattct ttgaagaaca tgtctacggt
    17761 taaaagtgtt accttttcaa gtaaagaaga acaatatgaa aaattaaccg agataatggg
    17821 agataactgg aaaatctttg aaggagatgc caatcctctc tatgatgcct atattgtaga
    17881 ggcaaacact ccaaatgatg taaaaactat agccgaagat gctaaaaaaa ttgaaggtgt
    17941 ctctgaggtt caagatggcg gtgccaatac agaaagactc ttcaagttag cttcatttat
    18001 ccgtgtttgg ggactaggga ttgctgcttt gttaattttt atcgcagttt tcttgatttc
    18061 aaataccatt cgtattacca ttatttcccg cagtcgcgaa attcaaatca tgcgcttggt
    18121 cggagctaaa aacagttata tccgtggacc gttcttgtta gaaggagcct ttatcggttt
    18181 attgggagct atcgcaccat ctgttttggt ctttattgtt tatcaaattg tttaccaatc
    18241 tgtcaacaaa tcgttggtag ggcaaaatct atccatgatt agtccagatt tatttagtcc
    18301 gttgatgatt gccctactat ttgtgattgg ggttttcatt ggttcattgg gatcaggaat
    18361 atccatgcgc cgattcttga agatttaggt aaaatagctg cttttatgag gagattgtaa
    18421 aatctccttt tttgctacaa gagtttttga aaagagatgc gcagaagaaa agagcttcca
    18481 aagaagtccc ccagagaaga cttcttgatg gctaatttga acttgaaatt tggcgcacta
    18541 gaaatttttt ataaaaaagt gtaatttttt tataaaagcc tttacaaaaa aaattaaagt
    18601 ggtataatta aatcatagaa agtgcaaacg ttttcgtaaa acgtttgcct aaataaaaat
    18661 aaaggagatt tgaatgatga aagatacatt caaaaatgtc ttgtctttcg aattttggca
    18721 aaaattcggt aaggctttga tggtagttat cgcggttatg ccggctgctg gtttgatgat
    18781 ttcaatcggt aagtctatcg tgatgattaa cccaaccttt gcaccacttg tcatcacagg
    18841 tggaattctt gagcaaatcg gttggggggt tatcggtaac cttcacattt tgtttgccct
    18901 agccattgga ggaagctggg ctaaagaacg tgctggtggt gctttcgccg ctggtcttgc
    18961 cttcatcttg attaaccgta tcactggtac aatctttggt gtatcaggcg atatgttgaa
    19021 aaatccagat gctatggtaa ctactttctt tggtggttca atcaaagttg ctgattactt
    19081 tatcagtgtt cttgaagctc cagccttgaa catgggggta ttcgtaggga ttatctcagg
    19141 ttttgtaggg gcaactgctt acaacaaata ctacaacttc cgtaaacttc ctgatgcact
    19201 ttcattcttc aacgggaaac gtttcgtacc atttgtagtt attcttcgtt cagcaatcgc
    19261 tgcaattcta cttgctgctt tctggccagt agttcaaaca ggtatcaata atttcggtat
    19321 ctggattgcc aactcacaag aaactgctcc aattcttgca ccattcttgt atggtacttt
    19381 ggaacgtttg ctcttgccat ttggtcttca ccacatgttg actatcccaa tgaactacac
    19441 agctcttggt ggtacttatg acattttaac tggtgcagct aaaggtactc aagtattcgg
    19501 tcaagaccca ctatggcttg catgggtaac agaccttgta aaccttaaag gtactgatgc
    19561 tagtcaatac caacacttgt tagatacagt acatccagct cgtttcaaag ttggacaaat
    19621 gatcggttca ttcggtatct tgatgggtgt gattgttgct atctaccgta atgttgatgc
    19681 tgacaagaaa cataaataca aaggtatgat gattgcaaca gctcttgcaa cattcttgac
    19741 aggggttact gaaccaatcg aatacatgtt catgttcatc gcaacaccta tgtatcttgt
    19801 ttactcactt gttcaaggtg ctgccttcgc tatggctgac gtcgtaaacc tacgtatgca
    19861 ctcattcggt tcaatcgagt tcttgactcg tacacctatt gcaatcagtg ctggtattgg
    19921 tatggatatc gttaacttcg tttgggtaac tgttctcttt gctgtaatca tgtactttat
    19981 cgcaaacttc atgattcaaa aattcaacta cgcaactcca gggcgcaacg gaaactacga
    20041 aactgctgaa ggttcagaag aaaccagcag cgaagtgaaa gttgcagcag gttctcaagc
    20101 tgtaaacatt atcaaccttc ttggtggacg tgtaaacatc gttgatgttg atgcatgtat
    20161 gactcgtctt cgtgtaactg ttaaagatgc agataaagta ggaaatgcag agcaatggaa
    20221 agcagaagga gctatgggtc ttgtgatgaa aggacaaggg gttcaagcta tctacggtcc
    20281 aaaagctgac atattgaaat ctgatatcca agatatcctt gattcaggtg aaatcattcc
    20341 tgaaactctt ccaagccaaa tgactgaagc acaacaaaac actgttcact tcaaagatct
    20401 tactgaggaa gtttattcag tagcagacgg tcaagttgtt ggtttggaac aagtaaagga
    20461 tccagtattt gctcaaaaaa tgatgggtga tggatttgca gtagaacctg caaatggaaa
    20521 cattgtatct ccagtttcag gtactgtatc aagcatcttc ccaacaaaac atgcttttgg
    20581 tattgtgacg gaagcaggtc ttgaagtatt ggttcacatt ggtttggaca cagtaagtct
    20641 tgaaggtaaa ccatttacag ttcatgttgc tgaaggacaa aaagttgcag caggagatct
    20701 ccttgtcaca gctgacttga atgctatccg tgcagcagga cgtgaaactt caacagtagt
    20761 tgtcttcaca aatggtgatg caattaaatc agttaaatta gaaaaaacag gttctcttgc
    20821 agctaaaaca gcagttgcta aagtagaatt gtaatatact tgaggttgga agctgtattc
    20881 caacctctta ttttgggaga aaagaatgaa atttttaaca ctcaatactc acagttggat
    20941 ggagaaagaa gcagaggaaa aattccagat tttgcttgaa gatattcttg aaaaggacta
    21001 tgatttgatt tgtttccaag aaatcaatca ggagatgacc tcgtcagagg tggaggttaa
    21061 tgacctttat caagctttgc cagcagctga gcctattcac caagaccatt atgttagact
    21121 cttggttgaa aagttgttag agcaagggaa aaattactac tggacctggg cttataacca
    21181 tatcggctat gaccgctacc acgaaggtgt ggctatcttg tctaaaacac ctattgaagc
    21241 cagagaaatt ttggtttcag atgtggatga tccaacagac tatcatactc gccgtgttgc
    21301 cctagctgaa actgtagtcg atggcaagga gctagcagtt gccagtgttc atctctcttg
    21361 gtgggataaa ggtttccaag aagaatgggc acgatttgag gctgtcttga aaaaattgaa
    21421 caagccactt ttactagctg gagattttaa caacccagca ggtcaggaag gttaccaagc
    21481 tattttagct agtccattag gcttacaaga cgcatttgaa gttgctcaag agaaaagtgg
    21541 tagctatact gttccgcctg aaattgatgg ctggaaaggg aacactgaac cccttagaat
    21601 cgattatgtc tttactacca aagagttagc ggtggaaaat ttacatgtcg tatttgatgg
    21661 taacaagagt ccacaagtga gtgatcacta tggcttgaat gctatattaa actggaaata
    21721 ataactgaaa agaggttgga actataaaat tccagccttt tcttactaga gaagctactg
    21781 gaaatagcct aaataagtga gactactgta atggaataaa atatggtata attgataaga
    21841 tagatagaat cgaggatgtt atgtcattta cgaaatttca atttaaaaac tatattagag
    21901 aagccttgaa ggagttaaaa tttacaactc caacagaggt gcaagacaag ttgattccta
    21961 ttgttttggc aggtcgtgac ctagtaggag aatcaaaaac aggttcaggt aagactcata
    22021 ctttcttgtt accgattttc cagcaattag atgaagctag cgatagtgtg caagcagtga
    22081 ttactgcacc gagtcgtgag ttggctactc aaatttacca agtagcgcgt cagatttcag
    22141 ctcactcaga tgtcgaagtt cgtgtggtta attatgtggg tggtacggat aaggctcgcc
    22201 agattgagaa attggcaagc aatcagcctc atattgttat tggaacacca ggccgtatct
    22261 acgacttggt taaatctggt gatttagcta ttcataaagc caagacattt gttgttgatg
    22321 aagcagatat gaccttggat atgggattct tggaaactgt tgataagatt gctggcagtc
    22381 ttccaaaaga cttgcaattc atggtcttct cagcgactat cccacaaaaa ctgcaaccat
    22441 tcttgaaaaa atacttatca aatcctgtta tggagaaaat taagaccaaa acggttattt
    22501 ctgacaccat tgataattgg ttgatttcga ccaagggaca tgataagaat gctcaaattt
    22561 accagttgac tcagttgatg cagccgtatt tggcaatgat ttttgttaac actaaaacgc
    22621 gtgctgatga attgcattca tatctgactg ctcaaggctt gaaggttgca aaaatccatg
    22681 gcgatattgc ccctcgtgaa cgcaagcgaa tcatgaatca ggtgcaaaat ctggattttg
    22741 agtatattgt cgcaacagat ttggcagcac gtgggattga cattgaaggt gtcagccatg
    22801 tcatcaatga tgccattccg caagacttat ctttttttgt tcatcgtgtt ggtcgtactg
    22861 gacgaaatgg cctaccaggt acagctatta ccctttatca gccaagtgat gactcggata
    22921 tccgtgagtt ggagaaattg ggaatcaagt ttagtcctaa gatggtcaaa gacggggaat
    22981 ttcaagatac ctatgaccgt gatcgtcgtg ccaaccgtga gaaaaaacaa gataaacttg
    23041 atatcgaaat gattggtttg attaaaaaga aaaagaaaaa agtcaaaccg ggttataaga
    23101 agaaaattca atgggcggtt gatgaaaagc gccgtaaaac caagcgtgct gaaaatcgcg
    23161 ctcgcggtcg tgcagagcgt aaagctaaac gccaaacatt ttaatagaaa ttgttggagt
    23221 actgagctcc aactttttta tttatgagaa cgaactatct aaaccgaaac actacattaa
    23281 agactgcaaa ttgcgattaa aaatggtata atgataaagt tatatagtcc cgataagatg
    23341 gtaggtattt attacgaaga gttttcctat cagtagtttg caattcgcaa agaatgacgg
    23401 cttcgaggtc gctcgtcttt ctatggttgc tgccatactg cggtcaccct atgcgcctta
    23461 ctagcttcag aaataaaaaa gtatcgtttt tatttctgaa gctagtaact cttagataat
    23521 ggaaattcct atcagtactt tgtaactcta taacaatatt ttttaagggg ggacattttt
    23581 atgtcagaac gtaaattatt cacgtctgaa tctgtatctg aggggcatcc ggataagatt
    23641 gcagaccaaa tttcagatgc gattttggat gctattttag caaaggatcc agaggcgcac
    23701 gttgctgctg aaacagctgt atatactggt tctgtccacg tttttggtga aatttctaca
    23761 aatgcctatg tggatattaa ccgtgtggtt cgtgatacca ttgcagagat tggttatacc
    23821 aatacagaat atggattttc tgctgagacg gtgggagtac acccatcttt ggtggaacaa
    23881 tctcctgaca tcgctcaagg tgttaacgaa gccttggagg ttcgtggaaa tgctgatcaa
    23941 gatccactgg acttgattgg agcaggtgac caagggctca tgtttggatt tgcagtagat
    24001 gaaacagaag agctcatgcc attgccaatt gcactcagtc ataaattggt tcgtcgtctg
    24061 gcagaacttc gtaagtctgg agaaattagc tatctccgtc cagatgcaaa atcacaagtt
    24121 acagttgagt acgatgaaaa tgaccgtccg gtacgtgtag atacagtcgt tatttctact
    24181 cagcatgatc cagaggccac taatgaacaa atccatcaag atgtgattga caaggtcatc
    24241 aaagaagtta ttccatcttc ttatcttgat gataagacaa aattctttat caatccgaca
    24301 ggtcgttttg taatcggtgg tcctcaaggg gactcaggtt tgactggtcg taagattatt
    24361 gtagatactt atggtggcta ctctcgtcat ggtggtggtg ccttctctgg taaagatgcg
    24421 actaaggtgg atcgttcagc ctcttatgcg gctcgctata ttgccaagaa tatcgttgca
    24481 gcaggccttg ctaagaaggc agaagtgcag ttggcctatg ctatcggtgt tgcgcaacct
    24541 gtttctgttc gtatcgatac tttcggtaca ggaacagtag ctgaaagtca acttgaaaaa
    24601 gcggctcgtc aaatctttga ccttcgccct gcagggatta tccaaatgct ggacctcaag
    24661 cgtccaattt accgtcaaac atcggcttac ggtcacatgg gacgtacaga tattgatctt
    24721 ccatgggaac gtttggataa ggtagatgct ttgaaagaag cagtaaaata agattttaag
    24781 aggggaacgt cctctctttt ttatagtttt taactatact gggatactgt tctgaaaatc
    24841 cattttgcga aagtagagat ttacatgtat agtagattga aactagaata gtacacctca
    24901 acttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttctc ctgttcttgt
    24961 ttcattttac tatatttctt taaaaatgat aaaggttgag atttctcctc gtaatagata
    25021 atcatggaga tatttcaatc caaagtttta ttcgttatca cttgactatt gcaaggtttt
    25081 ctagagcaac agagtcatgg aatggactca tggttgagat ttctccttgt tgcttggact
    25141 tcattcaaaa gtctgttacc caagccttgt tcaaacttct aatacactag ctgtttccat
    25201 agcatgactt ctgtactaga ctttcttttc cgaataaata gatagaacca cagaatctag
    25261 taaacctaga attaaaatta tggtataata ttagcaataa aagaaatctg gaggattaga
    25321 atcatggtat caacgaaaac acaaattgct ggttttgagt ttgacaattg cttgatgaat
    25381 gcagcaggtg tggcttgtat gacgatagag gagttagaag aggtcaaaaa ctcagcggca
    25441 ggaacctttg ttactaagac agcgaccttg gacttccgtc aggggaatcc tgagccacgc
    25501 taccaagatg ttccacttgg ttccatcaac tctatgggct tgccaaataa tggcttagac
    25561 tattatttgg attatctttt agatttgcag gaaaaagagt cgaaccgaac tttcttctta
    25621 tctctggtcg gcatgtctcc agaggaaacc catactattt tgaaaaaagt ccaagagagt
    25681 gattttcgtg gtctgactga gctaaatctt tcctgtccaa atgttccagg taaacctcag
    25741 attgcctatg attttgagac aacagaccgg attttggcag aagtgtttgc ttacttcacc
    25801 aaacctcttg gaattaaatt gccaccttat tttgatattg ttcactttga tcaagcggca
    25861 gctattttca acaaatatcc gctcaagttt gtcaactgcg ttaactctat cggaaacggc
    25921 ctctatatag aagacgaatc tgtcgttatt cggcctaaga atggttttgg tggaattggt
    25981 ggagaataca tcaaaccgac tgctttagcc aatgttcacg ccttttatca acgtttaaat
    26041 cctcaaatcc aaattatcgg aacaggtggc gttctgactg gtcgagatgc ctttgaacac
    26101 atcctctgtg gagcaagtat ggtgcaggtg ggaacgaccc ttcacaaaga aggcgtcagt
    26161 gcttttgacc gcattaccaa tgaactgaaa gcaatcatgg tggaaaaagg ctacgagagc
    26221 ttagaagatt tccgtgggaa attgcgctat attgactaaa ttaaatcgaa aaatctgaag
    26281 aaaggagaga cgatgctagc cattgaagaa agtcagaagt tgactttatc aaatttaccg
    26341 agcctgagcc tatttacagg gacagatcag ggtcagtttg aagtgatgaa gagtcaaatg
    26401 ttgaaacaga ttgggtatga ttctgctgac ctcaactttg cctactttga tatgaaagaa
    26461 gtagtttaca aggatgtgga actggagttg gtcagccttc ctttctttgc ggatgagaaa
    26521 atcgtgatat tagattattt tatggatatc acgactgcta agaaacgctt tttggcagat
    26581 gatgagctta agtcatttga ggaatacctt gacaatcctt ctccaacaac caagttgata
    26641 atctttgcag aaggaaagct ggatagcaaa agacggttag tcaaattact taagcgtgat
    26701 gccaaggtct tcgatgcagt agaagtaaaa gaacaagaat tgcgccagta tttccaaaag
    26761 tggagtcaga aacaaggtct gcagtttacc aatcattctt ttgaaaatct cctcatcaag
    26821 tcggggtttc aatttagcga aatccagaaa aatcttctct ttttacagtc ctataaggcg
    26881 aattctgtta tcgaggaaga ggatattgtt aacgcaattc ccaagacctt gcaggacaat
    26941 atttttgatt taactcagtt tattctgact aaaaagatgg atcaggcgcg cgatttggtg
    27001 agagacttga ccttgcaagg ggaagatgaa atcaaactga ttgcagtcat gctgggacaa
    27061 tttcggactt ttactcaggt gaagattttg gcggagtctg gccaaacaga atcgcagatt
    27121 gcaagtagtt taggtagtta tctgggacgt aacccaaatc cttatcaaat caagtttgca
    27181 ttaagagatt cgagaggact ttctttgagc tttctgaagc aagctatttc ctatttgatt
    27241 gagacagact atcagattaa gacaggtctt tatgaaaaag gtttcctttt tgaaaaggca
    27301 ctcttacaga ttgctagtca ggtcaattga catttgttga aactacaacc cgcgtcagga
    27361 ttatcttgtc gtgggtttct tgctgatttg cttattttat tagaaagtat gtcagtgatt
    27421 tccttatcta taagcaaaaa acttgaaaaa agtgaatgtt tgcgttatca ttttcatata
    27481 gaaagaaaaa gaggtattac agatggctat tatcttacca gaacttccat atgcatacga
    27541 cgctttggaa ccatacatcg atgcggaaac aatgcatttg caccatgaca aacaccatca
    27601 aacttatgtc aacaatgcca atgcagcttt agaaaaacac cctgaaatcg gtgaagacct
    27661 tgaagccttg cttgctgatg tagaatctat cccagctgat atccgtcaag cacttatcaa
    27721 caatggtggc ggacacttga accacgctct tttctgggaa ttgatgactc ccgagaaaac
    27781 agctccttca gcagaactgg cagcagcaat cgatgcaaca tttggttcat ttgaagaatt
    27841 ccaagcagcc ttcactgcag cagcaacaac tcgttttggt tcaggttggg catggttggt
    27901 tgtcaacaaa gaagggaaac ttgaagtgac ttcaacagca aaccaagaca caccaatctc
    27961 agaaggtaaa aaaccaatct tgggcttgga cgtttgggaa catgcttact acgtgaaata
    28021 ccgcaacgtg cgtcctgact atatcaaagc tttcttttca gtaatcaact ggaataaagt
    28081 agatgaattg tacgcagctg ctaaataatg atagttggag ggaagaattg ttcttctctt
    28141 ttttaggtta taagattctg gtctgacaaa atcgtcagac ttttttcatt tttatgagaa
    28201 acgtgctaac tgctagaaat tatggtagaa taaagtatta agtaatcgtg gaaaaaggat
    28261 atctatgcga aaagaaattg cacctgaatt atacaactat aacaagtttc ctggtccgga
    28321 gttccattta cacggggaca aggtcgaaac ggaagggata gctttttcct tggttgaaaa
    28381 tatcaaggat gcctttgatg tgacgacttt taatcagcgt ttttcagaag tattaaccaa
    28441 gtttgattat atcgtggggg actggagcaa cgaacagctt cgcctacgag gtttttacaa
    28501 ggatgaccga acagaagaaa aacttgaaaa aatcagtcgt ttacaagact atcttttaga
    28561 gtattgtagt tatggttgtg cctattttgt cttagaaaat gaagccccta agcgagcatc
    28621 atttgacaag aaaatgcgta agacggaaga agaaacacct tctagaaaag gaaagaaacc
    28681 gactcaaact aaacgaaagt cgaatgcaga taagaaaaat agacgtcgtc agaaagacca
    28741 gcattctcag aaagaggaca aggaacaacg tcattttgtc attcgtcaga agtgagtaga
    28801 gaataaggag aagaaatgaa accctcaatt catagtttgg cacatcaaac catgcaggaa
    28861 tgggtattgg agcagggaga aaagaaattc cgtgcagatc aaatctggga atggctctac
    28921 cgtaaacgtg tgcagtcatt tgaagaaatg accaaccttt ccaaggattt gattgctaag
    28981 ctcaatgacc agtttgtggt caatcccttg aaacaacgta ttgtgcaaga gtctgctgat
    29041 ggtacagtca aatatctctt tgaattgcct gacggtatgt taattgagac tgtactcatg
    29101 tgtcaacact atggtttatc tgtctgtgtg accactcagg tcggctgtaa tatcggttgt
    29161 accttctgtg cctctggttt gattaagaag cagcgtgacc tcaataacgg tgaaatcgta
    29221 gcgcaaatca tgctggttca gaaatacttt gatgagcgtg gtcaggatga acgcgtcagc
    29281 catatcgttg tcatgggaat cggtgagccc tttgataatt acaacaatgt cttgaatttc
    29341 tttcgtacta tcaatgatga taaaggaatg gctatcggtg ctcgtcacat catggtttca
    29401 acctcaggtt tggctcataa aattcgtgac tttgctgatg aaggggttca ggtcaatctt
    29461 gccgtgtctc ttcacgcacc caacaatgaa cttcgttcaa gtatcatgaa aattaaccgt
    29521 gcctttccga ttgaaaaact ctttgctgct attgaatact acattgagac aacaaaccat
    29581 cgtgtaacct ttgaatatat catgcttaat gaagtcaacg acggtgtaga acaagccttg
    29641 gaattggctg aattgctcaa gaacatcaag aaattgtctt atgtaaactt gattccttat
    29701 aacccagtta gtgagcatga ccaatatagc cgtagtccca aagagcgcgt gttggctttc
    29761 tatgatacgc ttaagaaaaa aggggtcaac tgtgtggttc gtcaagagca tggtacagat
    29821 attgacgcag cttgtggaca attgcgctct aacacaatga aacgtgaccg ccagaaggca
    29881 gtcgcagcgg taaatcctta atgatgaaga agacttataa tcatattttg gtctggggag
    29941 tcattttcta tagcatttgc attgtctgtt tttgctttac tcctcaagaa caatctaccg
    30001 tgggagtggg aactccagat attcagcatc ttggacgcct ggtttttctt ttgactcctt
    30061 tcaattctct ctggaaactg ggcgaagtga gtgacattgg acaattatgt tggatttttt
    30121 tacaaaatat cctcaatgtc ttcttgtttt ttcctctgat tttccaactc ctttatctat
    30181 ttccaaattt gcggaaaaca aaaaaggtcc ttctttttag ttttcttgtg agtcttggaa
    30241 tcgagtgtac gcaattaatc ttggactttt tctttgattt caatcgcgtc tttgagattg
    30301 atgatttgtg gaccaacact ttgggtggct atctggcttg gctcctttat aaacgattac
    30361 ataaaaacaa gataaggaat taaaatgagt attttagaag ttaaaaatct gagtcacggt
    30421 tttggtgacc gtgcaatttt tgaagatgtg tccttccgtc tcctcaaggg agaacatatc
    30481 ggcctggtcg gtgccaatgg tgaaggaaaa tcaaccttta tgagtatcgt gactggtaaa
    30541 atgctgccag atgaaggaaa ggttgagtgg tccaaatatg tgacggctgg ttacttggat
    30601 cagcactctg tccttgctga aagacagtcg gtgcgtgatg ttctccgtac ggcttttgat
    30661 gagcttttca aagctgaagc tcgtatcaat gacctctata tgaaaatggc tgaagacggc
    30721 gcggatgttg atgctctcat ggaagaagta ggagaacttc aagaccgtct ggagagtcgt
    30781 gatttctata ccttggatgc taagattgac gaagtagcgc gtgctcttgg tgttatggac
    30841 tttggcatgg atacggatgt aacttctttg tcaggtgggc aaagaaccaa ggtgcttttg
    30901 gcaaaacttc tccttgaaaa gcctgatatt ttgctgttgg acgagccgac caactacttg
    30961 gatgctgagc atattgattg gctcaagcgc tatctccaaa actatgagaa tgcctttgtt
    31021 ctcatttcgc acgatattcc attcctcaat gacgttatca atattgtcta tcatgtggaa
    31081 aatcaacagc tgacgcgtta ctctggtgac tactaccagt tccaagaagt ttatgctatg
    31141 aagaaatctc agctagaggc agcctacgaa cgccagcaga aagagattgc agacctcaag
    31201 gactttgtgg ctcgtaataa agcccgtgtt gcaactcgta atatggctat gtctcgtcaa
    31261 aagaaattgg ataagatgga tattatcgaa ctccaaagtg agaaaccaaa accatccttt
    31321 gatttcaaac cagctcgtac accagggcgc tttatcttcc aagccaagaa cttgcaaatt
    31381 ggttacgacc gtcctcttac taagccttta aatcttacct tcgaacgcaa tcaaaaggtt
    31441 gcgattattg gtgctaatgg tattggaaaa acaactctct tgaagagtct cttgggcatt
    31501 atctcgccaa tcgctgggga agtggagcgt ggagattatt tagaacttgg ttattttgag
    31561 caggaagtag aaggcggtaa tcgccaaact cctcttgaag ctgtctggaa tgcctttcct
    31621 gcccttaatc aagcagaagt ccgtgcagcc cttgcccgtt gtggtttgac aaccaaacat
    31681 attgaaagcc agattcaagt attatcaggg ggagagcaag ccaaggttcg tttctgtctc
    31741 ttgatgaatc gtgaaaacaa cgttttagtg ctggacgagc cgaccaacca tttggatgtg
    31801 gatgcaaagg atgagctcaa acgcgctctc aaagaatata ggggatctat ccttatggtc
    31861 tgccacgagc cagactttta tgaaggctgg atagaccaaa tatgggattt taataattta
    31921 acttaagaat gagagtaaaa gaaatacagt accgaatgtg gatactgtat ttttttggtt
    31981 tttaagattt aaaatcgtag tctttcacca cttcgatgct gtcgattgtg atagcagtag
    32041 ttggcttgtc tttttcatct ttttcggcct tagcaatctt atccacaaca tccataccgt
    32101 caatcacttg accaaagact gggtgtttgc catctagact agggtttcca ccttctttgt
    32161 aggcttcgat aattttctgt ggatacttgc ttgtagggag tttagaagag gtatctgtag
    32221 agttttggtt gatgaagaac tggctgccat tggtgtttgg ttgaccagta ttagccatag
    32281 caagagcacc gcggatgtta tacaaataag gagtaatctc gttcttgaaa ccagttcctt
    32341 tgtctttagt cttatccttg tcatgccaga tggactgacc acctgtaccg tccccttttg
    32401 gatctccagt ttggaccata aagccatcga tgacacggtg gaaggtaata ccgttatagt
    32461 agccttcttt ggcgtgagtg aggaaatttt caaccgctag aggagcgagt ttagggaaga
    32521 gtttaatgcg aatatcacct tggcttgtgt ggagaatcac ttcggcttca tcttcagcaa
    32581 cttccttaga tagttgtggg aaattggcgt tttcgtttgt taaagcatcg tttaactcct
    32641 tggcagattg ggcagctact ttggaacttt cttcagcagc aagactggaa tcaacataat
    32701 catcaccacg cagactgcgt tggacgctgc tacacccagc tagggctaca gtagacagta
    32761 aaagaagggt tgctagtttt ttcattctga tcctctcaaa aattcattta taaccattgt
    32821 accctaaaag gaagtggatt tcaaatatta gtagtttaca gaactggctt agataatagt
    32881 tgggatttca tcatcatctt gaaaatcttc aacttcttcc ccagtaaatg gtttctgaaa
    32941 agaacttagt ataaaacggg caattggttc aacaattagg aaatttagag gaagagctgc
    33001 aataaagttt acgaaccagg cgcttagata ggtattgggt gtgatagcaa tgccattgta
    33061 aaaaagtcca tagaaggaca tgaaagtgac cagctaattc ttcttctgaa aaatgctcat
    33121 gaagggcttg atccaggtcg caagatttca ttttagaaag tccagtaact cccttcttct
    33181 tcaggatatt ctttttcatg gtattattta gatggtcaag tgagtcaaaa gaagtttcga
    33241 caagagcata ccctttttct accagagttt ttagatgttt aggggcatca ataccataag
    33301 tgtactcaaa gtattttgga aaccagatct taagaaagct cgtaaagcta gccagttctc
    33361 taaacgctaa gaactagcta caacacagca tttacaacac ttcatggttc acaccatggg
    33421 gtgtttttta atgattttaa gcaaaattca cacttaattg aaagttattt aaattagatg
    33481 aaaatttatt ttttgaaaaa gtgggaaaac attgattcta agcgaatttt gaatcatatt
    33541 cgaatgggag tttttaaaat catgtttcag tggtaaaagt accaaactgg attctccata
    33601 gtaaaatgat atctcctgct agtgaatcat ctactaataa gtccatattt cgcttgggaa
    33661 cgggcttggg acttagaagc caagtatcca actctcgttc aggcgatatg aagggtttga
    33721 cttggtgttc tttataaaat ttttctaaaa tagtattcac ggatagcatc tttcaaacat
    33781 ttatttccta ttctaacaaa tttctaaata ctttaagaaa tttatagtct gtcaagtttt
    33841 tttcttgaca catgccagaa atctgctata atagaacatg tgctaaatag ctcagctatt
    33901 tcaccgaaat aaaaaattaa agaaatgaga ctttaaaaat ggcagttaaa atccgtttga
    33961 ctcgtatggg ttctaagaaa aaacctttct accgtatcaa cgtagcagat tcacgttcac
    34021 cacgtgacgg acgtttcatc gaaacagttg gaacttacaa cccacttgtt gctgaaaacc
    34081 aagtaacttt gaaagaagac cgcgttcttg catggttggc taatggagct caaccttcag
    34141 acacagtacg taacatcctt tcaaaagaag gcgtattgaa aaaattccac gattctaaat
    34201 tctcaaaata agtttaaagt aggttgacag atggatacga ttgaaaatct cattattgcg
    34261 attgtgaaac ccttaatttc acaaccagat gccttaacta tcaagattga ggatacacca
    34321 gaatttttgg aatatcattt gaatcttgat caaagcgatg tgggtcgtgt aatcggtcgt
    34381 aagggtcgca ctatttctgc gataagaacg attgtctact ctgtcccaac tgaatacaaa
    34441 aaagtaagaa tcgttattga cgaaaaataa gaagggcggg acggatgtct cgcttttttg
    34501 tgtggaatag aagatatagt aaaatgaaat aataacagga caaatcgatc aggacagtca
    34561 aatcgatttc taacaatgtt ttagaagtaa aggtgtacta ttctagtttc aatatactat
    34621 aaaagattga acgtttaggc aattccaaga ctacttactc gaacattaac agcagtctcg
    34681 gactgatgaa ggtctcttta tgaagttagt ggaggaagtc ggagaagtag ccgaggtttt
    34741 gaataggcgc tctggtcgaa aagaagggat aggattcgaa cgaggaactt gccagagaac
    34801 tggctgatat catttactac accgtcgcaa tcgtagctat taatcatatt gaccttacca
    34861 agactgtctt tgagaaagac aaaaccgcag ccgttaatta ccaacataaa catgatttgg
    34921 aaggattttt gaagggaaag tagagatgtt gtccccttcc tccaacttga gaaaatcctt
    34981 ggaacgtgat aaaataaagg ataaggattt ttaataattc attatataga atgagtggat
    35041 ttctttatga agaggtttga agtatctaca gaaattggta gtctctctgt tgcttatcaa
    35101 aagcaaaaga aagtgctagt ttgtctaaac ggagcaggtt tgctaccaag ttatgaaaat
    35161 ttttcactta tacttgaaaa acctcctcct acaattggtt atttgacaat tgattttccg
    35221 aacacaggta ggagtccgat tcatgaccaa gctggaaaaa atctagataa tcttgcagat
    35281 gtggtttatg aagtacttga agaattaggg atttctgaat atatactttg tgcacatagt
    35341 tggagtggaa ttttagcttg caaattactc gagaaaccaa ttaagtgtca gactttagta
    35401 gcaattgaac cgacaactaa aaaagtcatg tttgctgatt tttcagaaaa tccttatcca
    35461 gaaatggaag agcagatgag gctgattgac gagtgtggtc ctgaacttta ttttaagaac
    35521 ttaactcaag caacatttag tcctgaaacg aataaaaaaa tctgggaatt gatgcaagaa
    35581 aaaggcttag agttggaaaa tcaagatcca gaatttcaga tatctggaga gattactgag
    35641 gaagattttg aggatgtatc tatagaagct catattcctg tatttgtttt ttgtcagcct
    35701 tatagagaaa aagagtacag agaatcagaa tattggactt ccaatactaa actcatttta
    35761 ggagggaatc accattattt acaatggtca gaatcggaaa aaattgcggc tattattcga
    35821 gaattgtcag aataagatgg aaaaaaggag attacaggag acaagatgaa ctactttaat
    35881 gttgggaaaa tcgttaatac gcagggatta cagggtgaga tgcgagtctt gtctgtgacg
    35941 gattttgcag aagaacggtt taaaaaagga gctgagctgg ctttgtttga tgaaaaagat
    36001 cagtttgtcc aaacagtgac catcgctagc caccgtaaac agaagaactt tgacattatt
    36061 aaattcaaag atatgtacca tatcaatact atcgaaaagt acaagggata tagtctcaag
    36121 gtcgctgagg aagatttgaa tgacctagac gatggtgaat tttactatca cgagattatc
    36181 ggtttggaag tctatgaggg tgatagcttg gttggaacca tcaaggaaat cctgcaacca
    36241 ggtgctaatg atgtctgggt ggtcaaacga aaaggcaaac gtgatttgct tttaccttat
    36301 atcccaccag tggttctcaa tgttgatatt ccaaataaac gggtcgatgt ggaaatctta
    36361 gaagggttag acgatgaaga ttgatatttt aaccctcttt ccagagatgt tttctccact
    36421 ggagcactca atcgttggaa aggctcgaga aaaagggctc ttggatatcc agtatcataa
    36481 ttttcgagaa aatgctgaaa aggcccgtca tgtagatgat gagccctacg gaggcggtca
    36541 gggtatgttg ctcagagcac aacctatttt cgattccttt gatgctattg aaaagaaaaa
    36601 tccgcgcgtt attctcctcg atcctgctgg aaagcagttt gatcaggctt atgctgaaga
    36661 tttggctcaa gaggaagagc taatctttat ctgtgggcac tatgagggtt atgatgagcg
    36721 cattaagacc ttggtaacag atgagatttc cctaggcgac tatgtcctca ctggtggaga
    36781 attggcagct atgaccatga ttgatgctac agttcgcctg attccagaag tgattggcaa
    36841 ggagtctagc caccaagatg atagtttttc ttcgggtctt ttagaatatc ctcagtatac
    36901 acgtccctat gattatcgag gcatggtcgt gccagatgta ttgatgagtg gtcaccatga
    36961 aaagattcgt cagtggcgat tgtacgagag tttaaagaaa acctacgagc gcagaccaga
    37021 tttacttgaa cattatcaac tgacagtaga agaagaaaaa atgctggcag aaatcaaaga
    37081 aaacaaagaa taaaggagaa acctatgcaa gtaatcaaac gtaatggcga aattgctgaa
    37141 tttaatccag ataagattta ccaagccatc ttgaaggcag cccaaactgt ttatgttttg
    37201 acagatgatt tgcgtcaaaa tcttgctcaa gtcactaaga aggtagtttt ggatttacaa
    37261 gaagccaagg tggaacgtgc gactatcagt atgattcaat ctatggttga acatcgttta
    37321 ttgggcgcag gttacattac cattgcagaa cactacattt cctatcgttt acaacgtgac
    37381 ttggaaagaa gtggttatgg agatcatatt gcagttcatt tacattttga acaaattcgc
    37441 taagaaaaag agtgggatga agcaactaca tctcactctt tcttaaatct atttttttgg
    37501 gctgtttgga cagttgaggg gacaaatcgc aggcgttgaa tatcgcttat acggataatc
    37561 cggctcacat ttttggaaaa atttttcacg ataatttgct ggccttgctg atcatatttg
    37621 atgatgtcac ctgtaaagct tgtctcagat aagataaggt gaacagcggt ttgtttctgg
    37681 atagcctctt caatagtggc tgtaagggag ttggtttcag tctggtcagg ttggtcatat
    37741 ccatttaaaa aatcatgtat tttatttaga acttgctgga atttatgtat catattggcc
    37801 tcccttcttt tatatcaata ttatataaaa ttttcctaaa atctacaaga ttttacgaat
    37861 aaactaatga aactaaaaaa ggagaagaaa atggcagaat ttacatttga aatcgaagag
    37921 cacttgttga ctctttctga aaacgaaaaa ggttggacca aggaaattaa ccgtgtgagc
    37981 tttaatggtg cccccgcaaa gtttgatatt cgtgcttgga gtccagacca tactaaaatg
    38041 ggcaaaggga ttactctctc aaatgaagaa tttcaaacga tggtggatgc ctttaaaggc
    38101 aactaatact cttcgaaaat ctcttcaaac cgcgtcagct ttgccttgcc gtatgtatgg
    38161 ttactgactt cgtcagtttc atccacaacc tcaaaacagt gttttgagca gcctgcagct
    38221 agcttcctag tttgctcttt gatttt
//
LOCUS       DAVHBD010000018        35428 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000018 DAVHBD010000000
VERSION     DAVHBD010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.018"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            161..369
                     /locus_tag="VVK04_000960"
                     /pseudo
     CDS             161..369
                     /locus_tag="VVK04_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            525..863
                     /locus_tag="VVK04_000961"
     CDS             525..863
                     /locus_tag="VVK04_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU3989631.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            1053..2489
                     /locus_tag="VVK04_000962"
     CDS             1053..2489
                     /locus_tag="VVK04_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU3989632.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADMHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2541..2780
                     /locus_tag="VVK04_000963"
     CDS             2541..2780
                     /locus_tag="VVK04_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU3989633.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2910..3224
                     /locus_tag="VVK04_000964"
     CDS             2910..3224
                     /locus_tag="VVK04_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU3989634.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3342..5321
                     /locus_tag="VVK04_000965"
     CDS             3342..5321
                     /locus_tag="VVK04_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU3989635.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVEGLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            5331..5645
                     /locus_tag="VVK04_000966"
     CDS             5331..5645
                     /locus_tag="VVK04_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU3989636.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5676..6182
                     /locus_tag="VVK04_000967"
     CDS             5676..6182
                     /locus_tag="VVK04_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989637.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGSVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LKKNSLSL"
     gene            6262..7608
                     /gene="celB"
                     /locus_tag="VVK04_000968"
     CDS             6262..7608
                     /gene="celB"
                     /locus_tag="VVK04_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU3989638.1"
                     /translation="MDQQNGLFGFLENHVMGPMGRLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPFNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKYNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7990..8166
                     /locus_tag="VVK04_000969"
     CDS             7990..8166
                     /locus_tag="VVK04_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989639.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8558..10771
                     /locus_tag="VVK04_000970"
     CDS             8558..10771
                     /locus_tag="VVK04_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HEU3989640.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDEADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFRKAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVQTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSIYRDVSNI
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10993..11469)
                     /locus_tag="VVK04_000971"
     CDS             complement(10993..11469)
                     /locus_tag="VVK04_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU3989641.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11692..14892
                     /locus_tag="VVK04_000972"
     CDS             11692..14892
                     /locus_tag="VVK04_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU3989642.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEKIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLFAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSDPYKVYVNDKEASLTEQEKDYPETQSVFFESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            15273..15649
                     /gene="tnpA"
                     /locus_tag="VVK04_000973"
                     /pseudo
     CDS             15273..15649
                     /gene="tnpA"
                     /locus_tag="VVK04_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(16037..16666)
                     /locus_tag="VVK04_000974"
     CDS             complement(16037..16666)
                     /locus_tag="VVK04_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU3989643.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(16676..17677)
                     /locus_tag="VVK04_000975"
     CDS             complement(16676..17677)
                     /locus_tag="VVK04_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU3989644.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17708..18349)
                     /locus_tag="VVK04_000976"
     CDS             complement(17708..18349)
                     /locus_tag="VVK04_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU3989645.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGIVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18368..19183)
                     /locus_tag="VVK04_000977"
     CDS             complement(18368..19183)
                     /locus_tag="VVK04_000977"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU3989646.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19455..19889
                     /locus_tag="VVK04_000978"
     CDS             19455..19889
                     /locus_tag="VVK04_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU3989647.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            19901..21091
                     /locus_tag="VVK04_000979"
     CDS             19901..21091
                     /locus_tag="VVK04_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEU3989648.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            21102..21593
                     /locus_tag="VVK04_000980"
     CDS             21102..21593
                     /locus_tag="VVK04_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU3989649.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21608..22387
                     /locus_tag="VVK04_000981"
     CDS             21608..22387
                     /locus_tag="VVK04_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU3989650.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            22374..23192
                     /locus_tag="VVK04_000982"
     CDS             22374..23192
                     /locus_tag="VVK04_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU3989651.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTDKLVILTVIIGIIGSWLKILA"
     gene            23192..23485
                     /gene="yajC"
                     /locus_tag="VVK04_000983"
     CDS             23192..23485
                     /gene="yajC"
                     /locus_tag="VVK04_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU3989652.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRKEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            23507..25408
                     /locus_tag="VVK04_000984"
     CDS             23507..25408
                     /locus_tag="VVK04_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU3989653.1"
                     /translation="MKEERRQFFERIDGDQYRDYILSRCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWNQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKVYI
                     QKCKFFLFDWIEQVREFRPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEEELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPILATYHFFSDKMDLEEAYHFASKELKQQ
                     IETQILEDGSQFEQSILYHVEVYKALLDLCLLLPDLQDNFQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAMVLNKEDLFNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFRSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDT
                     GRYSYREVDERYLLKSAWSHSTCIVDGKAPERIVGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYLSAEPDLPYLHKRKILMLAEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            25468..26469
                     /locus_tag="VVK04_000985"
     CDS             25468..26469
                     /locus_tag="VVK04_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU3989654.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETRKKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(26579..26914)
                     /locus_tag="VVK04_000986"
     CDS             complement(26579..26914)
                     /locus_tag="VVK04_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989655.1"
                     /translation="MKSLARLLIIHVFISIFLFCALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLTYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(26925..27167)
                     /locus_tag="VVK04_000987"
     CDS             complement(26925..27167)
                     /locus_tag="VVK04_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989656.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(27183..27377)
                     /locus_tag="VVK04_000988"
     CDS             complement(27183..27377)
                     /locus_tag="VVK04_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3989657.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            27543..28493
                     /gene="rsmH"
                     /locus_tag="VVK04_000989"
     CDS             27543..28493
                     /gene="rsmH"
                     /locus_tag="VVK04_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU3989658.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            28505..28822
                     /gene="ftsL"
                     /locus_tag="VVK04_000990"
     CDS             28505..28822
                     /gene="ftsL"
                     /locus_tag="VVK04_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU3989659.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            28826..31078
                     /gene="pbpX"
                     /locus_tag="VVK04_000991"
     CDS             28826..31078
                     /gene="pbpX"
                     /locus_tag="VVK04_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU3989660.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            31080..32060
                     /locus_tag="VVK04_000992"
     CDS             31080..32060
                     /locus_tag="VVK04_000992"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU3989661.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYMQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            32669..34774
                     /locus_tag="VVK04_000993"
     CDS             32669..34774
                     /locus_tag="VVK04_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU3989662.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLLGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLNPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            35226..35366
                     /locus_tag="VVK04_000994"
                     /pseudo
     CDS             35226..35366
                     /locus_tag="VVK04_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        11174 a         5861 c         7675 g        10718 t
ORIGIN      
        1 aaaggtttgc cctatgggtg cttttttcgt gtttttttga aaagtttacc ttatttttat
       61 agtactgtga aataagaata ggacaaaccg aggatagtca aatcgaattc taacaacgtt
      121 ttagaagtag aggtgtacta ttctagtttc aatctactat attatggata atgcaagatt
      181 ccatagaatg ggtaagttag aactcttgtg tgaagagttt gggtataaac tttaacctct
      241 tcctccctac tcacctgagt acaatcctat tgagaaaaca tgggctcata tcaaaaagca
      301 cctcaaaaag gtattacaag ttgcaatacc ttttatgagg ctcttttgtc ttgttcttgt
      361 ttcaattgac tataaatcgc tataagaaaa aatcatttta ttggtataaa gaagtgattg
      421 aaagtaatgg cgaaacgtta gataattagt tcataaaaaa caagtttaga tcctcatcta
      481 aacttgtttt tttaaaattg aaggatgatt ttgaaggata taagatgaca ttgactattc
      541 atgtatatta taaaggtgat ggagatagtg caataaagtt tgcaagagaa atgcttgata
      601 gtggccttgt tgaagaaatt agaaatcaaa aaggtaactt gaaatacgaa tattttttac
      661 caattgaaaa agagggaact attctcctta ttgatcagtg gataaatcaa gaaactttag
      721 ataagcatca tcaatcaaag acaatgcaga aaatcttaga tttaagaaaa aaatatcact
      781 tgcagatgca agttgaacgt tatatagaag atgattctgg gatgccagaa agcgataagt
      841 cgtttataga cacagggaat tagaattatt gtgagagttt ttgtagtttg aaagtattga
      901 aaatcgtaaa gatatcatta cgagaataca agaagatatt gttctatttc cattaaaaat
      961 tacttctttc cttaataata aggaaaaaga atacgttttc atcttttggt ttgaggttta
     1021 taataagagt atcaaagtca ggaggaaaaa agatgactac ttttaaagat agatttttat
     1081 ggggtggtgc tgttgctgct catcaacttg aaggcggatg gcaagaaggt ggcaaaggaa
     1141 ttagtgttgc tgatgttatg actgctggtc gtcatggagt agctcgtgaa attacttcgg
     1201 gagttttaga gggtaaatat tatccaaatc atgaggcgat agatttttat catcgttata
     1261 aagaagacat agcacttttt gctgaaatgg gattcaagtg cttccgtacc tctattgcat
     1321 ggacacgtat ttttccaaaa ggtgatgagt tagagccgaa tgaagaagga ttacagtttt
     1381 atgataatct ttttgatgaa tgcttaaaga atggtattga acctgtcatc actctatctc
     1441 attttgaaat gccttatcac ttagtgaccg aatatggtgg ttggaaaaat aggaaattga
     1501 ttgatttctt tgctcgtttt gcagaagtcg tatttaaacg ttacaaagat aaggttaaat
     1561 attggatgac tttcaatgaa atcaataatc aagcgaatta tcaggaagat tttgcaccat
     1621 ttactaactc aggtattgta tatgaggaag gtgataatag agaggcaatt atgtatcaag
     1681 cagcacatta cgaattagtt gcttctgcac gagctgtaaa aattggtcat gagattaatc
     1741 cagattttca aataggttgt atgattgcga tgtgtccaat ttatccagct acttgcaatc
     1801 ctaaggatat cttaatggca atgaaagcta tgcagaagcg ttattatttt gctgatatgc
     1861 atgttttagg taaatatcct gagcatattt tcaagtattg ggaacgaaaa ggtatttcag
     1921 ttgattttac tgaccaggat aaagaagatt tacttggtgg gactgtagat tacattggtt
     1981 tcagttacta tatgtccttt gctatagact ctcatcgtga aaataatcct tattttgatt
     2041 atcttgaaac agaagattta gtgaaaaata attatgttaa ggcttctgaa tgggagtggc
     2101 aaattgatcc agaaggtttg cgttatgcgt taaattggtt tacagaccac tatcacttac
     2161 cactctttat tgttgaaaat ggttttggag ctatagatca agttgcagca gatggtatgg
     2221 tacatgatga ttatagaatt gaatatctag gtgcccatat tcgtgaaatg aaaaaggctg
     2281 tagttgaaga tggtgttgat ttaatgggtt atactccatg gggatgtatt gatttggttt
     2341 cagctggtac cggtgaaatg cggaaacgtt atggctttat ttatgtagat aaagatgaca
     2401 atgggaaggg aagttataat cgttccccga aaaaatcttt tggctggtat aaggaagtta
     2461 tttcatctaa cggtgaatca gtagaatagt ataaacaaac tgagattatt ctcagtttgt
     2521 ttagcatatt gaggtgacat atgattggaa gtattgcagc aattttaaca acatttgcat
     2581 ttttaccaca agtttttcgt gtagttaaga caaaggacac aggatctatt gctctaggta
     2641 tgtatgttat gcaagttatt ggtattgcat tgtggcttgc tcatggtatt cgtataggag
     2701 acttgccttt gattttagca aatagtgttt catttctact ctcaggaata attttatttt
     2761 ataaattgaa gtataaataa tttttttcca tatcatttag gaaaatgagg gaattgtcat
     2821 tggaaacgct ttattttata ataaaaatag ataacagata agtcaactta gcacagcttt
     2881 gattggattt aagaaaagga gaaaatatta tggcaaaagc tttaattatt tgtgcagcag
     2941 gaatgtcttc atcacttatg gcacagaaaa caacagagtt tctaaaagga aaagggaaag
     3001 atattgtagt tgatgctatt agtgctactg aaggagggaa agctatcgca gcagcagctt
     3061 ttgatttgta tcttgtcagc cctcaaacaa aaatgtactt taagcaattt gaagaggctg
     3121 gttctaaagc aggaaaacca gttgtacaaa tacctcctca agcctatatt cctattccaa
     3181 tgggaattga aaaaatggct aatttgattc ttgagaatat ttgatgaaca catgaaatgt
     3241 caataaatat ttaggttaag ataaattgtt ttgagtttga tataaactga tttaagtgta
     3301 taatatgctt caatatatga aaacatacgt tttaggaggg aatgaatgtg ttaaacatta
     3361 aagagaaaga tatccttcaa tttttaataa aaaataagga acgttttgtt acaagcaaag
     3421 aactggcaga atatttatcc tgttcagata gaactgtccg taatgtactg aaattaattg
     3481 agaagacaat gattattcaa ggagtccggt tgatttcaaa acaaggtcaa gggtatcaaa
     3541 tattttttga gaatcaaggc gcttaccagg agtttagaca aacttatgaa ctggaagaag
     3601 actatacgaa aactgcggtt tcaaaaggtg atgatcgttt agtatttatc ttaaataaat
     3661 tattatttga gcaagttcca gttctttttg atgatttagc tgatgaactt tacgttagtc
     3721 gttcaacatt atctcatgat ttcagaaaga tacgagtgat gttatcagag tataatttgt
     3781 ccattgagag tagggcgaat aaaggagttt atgtctcagg tgaggaacgt gataaacgac
     3841 gttttatcat aaattatttc ctagagaatc aattttttaa aacaatacat tgctatgtaa
     3901 aatttaactt ttttgctcaa actgttccat tagaagaatt tgctagaatt gttttggatg
     3961 aatgccaaga ggccaaccta aaactatctg attttgtact acagaattta gtagttcaca
     4021 tagcattgtc tgtgattcgt ttaaaatccg gatttgaaat aaaaaatata gactgtcaga
     4081 tgactgatga tgcaatagag agaaaggttg cccaaagaat tctttctaaa gtaagagaag
     4141 taacaaatca ggaatttcca gttcaggaaa tagactacat tactttgcat ttgttagcta
     4201 agagtcaaca atgtcaaaaa aatcagaaga atatttctga agaagtttta aaaaaatctt
     4261 tatttaaaac atttcagaat ttaggattag atgatatgta taacttttct tcagatttcc
     4321 aactaattga aggattgata actcatctaa tgacactaca agtacgttta gaaagccgga
     4381 ttaccttaaa taaccctttg gtagatgaaa ttaaacagaa ttatagtgat atattcttta
     4441 tgactagaga aattcttgca aatatggaca agttcttgga gtggacaata tcagatgatg
     4501 aagtagcata tgtaagtctt cactttttag ctgctatgga acgtagcaaa gagagtacta
     4561 agtttaatat tcttgctatt tgtgcaacag gatttggtgc agcccaaatg ttaagaaatc
     4621 gtttggaaac ggagtttggg aagcgagtag aagttgttga tgtaataggc tactatgaat
     4681 tgaatcaaga aaaacttaaa ggaatagatt ttatagtgtc agctgttgat ttatcaaatc
     4741 tatattttca aatcccagtt tttaaagtta gtgtgtttct taaaagtgat gagatggaaa
     4801 tgattagaaa agctatggat cagatgcaag tttctagtta tgtacaatca tcaaagatta
     4861 acaaatttga aaacaacggc tttagacagt attttagtaa agaaaatttt ttaatatgta
     4921 ctgaatcaga caaggtaaat ttacttgaaa agatggttga gggtttatct gttggtgaat
     4981 caaatgagtt tgaacaatct ttactttatg gaattaaaca gcgcgaagaa ttaagttcag
     5041 ttgttttttc tgaaaaaatt gcagttccgc atcctattca gccctttggt acagagggaa
     5101 aggtttcggt tgcaatttgt aaagattcgt tactctggga taatcaaagt tcacatgtcc
     5161 agctagtatt tcttctatct ccatcaatat atgggaacga aggtttagca actgtgacta
     5221 aaaagatagt ctctctgaca gagaatgatg aattgcaaaa tcagctaata tcttgcaata
     5281 actttgaaga ttttattaac atatttgaga agataaaata ggaggttcat atgaatcaag
     5341 aggaactgca ggttgcagca tttgaaatta tcctgcattc gggaaatgca aggtcagaaa
     5401 tacatgaagc atttgcaaaa atgagagaag gtagttttga tgatgcagaa agtaaattaa
     5461 atcaatcaaa tgagataatt cttgaagcgc atcatgcaca aaccaaactc ttgcaagaat
     5521 acgcaagtgg agtggaaatt aaaattgaaa ttatcatggt acatgctcaa gatcatttaa
     5581 tgaccactat gacattatta gaagtagcaa aggaaatgtt agctctttat aagaaagtta
     5641 actaaatatg tgttgttata taaggaggaa atgatatgga taaaaaagaa cgacaaaaaa
     5701 ttgaacaaca acgtcgagag atggctctaa ctaatacttt ttttaatcga tatcttcttc
     5761 tacgttattc aatagcactc ttcttttttg ggaatattta ttggcttttg aatcagttta
     5821 ttaatccctc gcctattatt attttcccca ttatgctcat agtattttct attttagcaa
     5881 ctattgaaca atttaaactt tatggaaata ggaaagaaaa gttgggaata acactaatgt
     5941 ttgttagaat acaaatgctt atttcaatag gattacttgt tttaacttgg acaagttggt
     6001 ttaagaatct ttttccgatt tttgaaaata accaagtagc acgtttattt gtttttgtag
     6061 ttcttctatt aggttcagtt ctgagtttgt tagacattag aagaattaaa aaaatttata
     6121 aacgaacaga taaggcttat caacaatttg tccaattgaa aaagaactca cttagtttat
     6181 aatcctgatc tagtataatt tgtatttgaa actagtcttt agaaagtaaa aattattatg
     6241 ttttattaag gaggtctatt tatggatcaa caaaacgggt tgtttggttt tcttgaaaac
     6301 catgttatgg gaccaatggg cagacttgct cagtttaaag tagtgcgtgc tatcacggct
     6361 gcaggtatgg ctgctgtacc atttactatt gtaggatcaa tgtttttggt attcagtatt
     6421 ttgccacaag ctttctcatt ttggccaatt gtggcagata ttttctctgc ttcatttgat
     6481 aaattcacat cactttacat ggttgcaaac tatgcgacta tgggttctct atctctttat
     6541 ttcgttctat cacttgcata tgaattgaca aaaatttatg cagaggaaga agaactcaat
     6601 atgaatcctt ttaatggtgc cttgctcgcc ttgatggctt ttgtcatgac agtaccgcaa
     6661 atcatttttg atggtggaat gatgaagact gtgacaagtc taaaagaagg tgcagtaatt
     6721 gcagatggat gggcaatggg aaatggagtc gcacgttttg ggacaacagg gatttttacc
     6781 gcaatcatta tggcaattgt gactgttctt atttatcgta tgtgtgttaa atataattgg
     6841 gttattaaaa tgcctgaagc tgttccagaa ggagtttctc gtggatttac cgctttggtt
     6901 ccgggatttg ttgttgcatt tgttgttatc tttatcaacg gtcttcttgt agcaatggga
     6961 acagatattt ttaaagtcat tgcaattcca tttggttttg tatccaatct gactaattcg
     7021 tggattggtt taatgattat ttatctactg actcaactac tttggattgt aggtatccac
     7081 ggtgcgaaca ttgtttttgc atttgttagt ccaattgctc ttgctaacat ggctgaaaat
     7141 gctgctggcg ggcacttcgc tgttgcaggt gaattttcta atatgtttgt aattgcaggt
     7201 ggttctggtg caactttagg actatgttta tatattgctt ttgcctctaa atctgaacag
     7261 cttaaagcaa taggacgagc atctgtagtt ccagccttat ttaatattaa tgaaccatta
     7321 atttttggat tacctattat ctataatcca gccttggcta taccatttat tttagcacca
     7381 atggttactg ctactattta ttacgtagcg aattctctaa actttattaa gccaattatc
     7441 gcacaggttc catggccaac tccagtaggg attggagctt tcttagggac agcagatctt
     7501 cgagctgtat tagttgctct agtatgtgca tttgcagcat tcctagttta tcttccattc
     7561 atccgtgtat atgatcaaaa attggtgaaa gaagagcaag gtatctaata agtaaaaaag
     7621 tatactcgat gatagaatcc atatagttta aataatgagt gttaacatta gcagtgaaga
     7681 gatcttttta agatattctt ctctgctttt tcattttatt tttttgctat gtagggtatg
     7741 aagcaaaata gaaagtagtt cgaatagttg ataaacaggg aactgctgtt atttaaaaaa
     7801 acaataaagt aaagtatgtt atcgtagaat acgatacaat agtaaaaaag caaaaagaat
     7861 gcgttttata tttgggtttg aggcttataa aataggataa gcgtgctgaa aacttagata
     7921 tgacaaacaa aataaaattt ttaaaagcta cagagaaaca tggtataatg taactaaagg
     7981 aggtagcata tgtccttaga tatagataaa gaaaagatga caatcatggg aatagctttt
     8041 gaaaaccgat ccgtttttaa gagtgtttgg tatgctttaa gtacaaatat gattgaagga
     8101 tggcgaccta cggttagtga tgttgaaaaa ttacgagatg aagctcttgc tctggggatg
     8161 acttaatgaa gcgcaactgt tatgaatctt atgactatgt tgatccggat aatttatata
     8221 ccgatccggg ttcttcagtt ctaagaaata agcaggaagg aaaaaagcac gtgagcttga
     8281 atatcgtatg attgctagta agagtttgaa attatttatc aatcctatct tagttaatag
     8341 tttaaaagta gtttgtttca caactgcata agcttagaaa agttgaaaag tgataactct
     8401 ttaataaact cttggttcgt taaaagatat tttgtccact acattttttc aattgactat
     8461 tatttgtcat agatagaaca ttgcattcag aataaggaaa aacgcatcaa aaatggtgcg
     8521 ttctgttttt atgctaccat aaaaggagga caacaaattg aaaattttta agggagagtt
     8581 ttatcgaatc tctgtattaa cagacaagtt agtaaggtta gaatactctc aaactggaag
     8641 ttttgaggat agaacgacac aacttatcta taatagagat tttggccaag tttcgttaga
     8701 ttatatcgag acatcaaacg tactagatat tatgacggac tattttcatc tgcactttaa
     8761 taaaggagaa tttaacgccg aaaatttatt tatagaatta aaaggaaatt ttgccgtata
     8821 tggtagtcgc tggtattttg gtgaatctat tgaaacgtta aaaggaacag ctcggactct
     8881 ggatgaggca gatggagcaa tctcgttaga agatggaatt attagccgaa atggtatagc
     8941 cttattggat gattctcaag gatttatttg ggatgaacaa tctggttata ttgagagaga
     9001 aaatcaaatt gacctgtatt tctttgccta tgggcatgat tatagaggag caatcagaga
     9061 tttttaccat ttgactggtt caacaccctt gttgccaaga tatgctttag gcaattggtg
     9121 gagtagatat tggccttata cgtcggatga atacttggat ttaatagaca gatttgaaac
     9181 agagaaaatt ccattatcta tcggtgtgtt agatatggat tggcatataa ctgacattcc
     9241 agctcgcttt ggaagtggct ggacaggata tagttggaat agaaacttaa taccaaatcc
     9301 agaacagtta ttgcaacaac ttcatgatag aaagctaaaa ctctccttaa atgtccatcc
     9361 tgctgatggg atacgggctt atgaagaagc ttatcctcaa atcgcaaaac ggttggggtt
     9421 aaatgtagaa ctagaagaac ctgctatttt tgattttttt aatccctctt ttaggaaagc
     9481 ctactttaaa gatgttcatt atgaactaga aaagcaggga gtagattttt ggtggattga
     9541 ctggcaacaa gggacacaag gtatgctaga tccactttgg cttttaaacc attatcacta
     9601 tcaggatagt tgtaaaaatg cagaaggtgg tttgatttta tcaagatatg caggtcctgg
     9661 tagtcaccgc taccctgttg gtttttcagg ggatactatt attagttgga attccttaag
     9721 atttcaaccc tattttacag cgacagcatc taatatcggt tatagttggt ggagtcatga
     9781 tatcggtgga catatgttgg gggattatga cgaagagcta caaactagat ggctacagtt
     9841 tggtgttttt agtccgatta ctcgattaca tagttctaga agtcctttta atagtaaaga
     9901 accttggttt ttttcagaaa caacatctaa gattatgaag aaataccttc gtttgagaca
     9961 tcagatgatt ccctatctat ataccatgaa tgtacagaca catgaggaag gtgccccatt
    10021 aatcagtcca atctattatt tctatccaga gaatgatgag agctataatg ttccaaacca
    10081 atactttttt ggaacagaac tgatggtggc tcccattgta gaaaagatgg atttgacatt
    10141 ccaatctgca aaagtagatg tatggttccc tgaaggtgaa tggtatgact tcttttcaga
    10201 gaaaaaatac acaggtggtg tgaagttaag tatttatagg gacgtttcga atattcctgt
    10261 gtttgcaaaa agtggtgcaa tcattccctt ggttggttct gagataggta tgggtgttga
    10321 tttacctgag gttgtagatt ggtatgtatt cccagggaaa caacattctt ttgaaatgct
    10381 tgaagatcaa aatggtcaaa gatataaaac aagattatca atcgattggg aaatgggaat
    10441 ggtagagtta gcattacaag gagattctag tatcgttcca agcaatagaa aacatagaat
    10501 tcattttaaa ggaacgaatg tgtctataat tgaattgcca aataagaatg atacagctaa
    10561 atttgaatgg aaagataata aaaggacatc tttaaatgac gaagttttta gactactaaa
    10621 gacagcttct cttccatatg aattaaaaga tagattgtta aatcaattca tcaatgcgaa
    10681 aaactctcat gacttaatga atatcttgca tcatcaggat aaggaattga gagggcgttt
    10741 gttggaaatg atatttacta gccaaaacta attgaaataa ttagaaagtc atttgtttag
    10801 tgtatatgaa gattctgtat ggtattcgtt atcactggtc acattgaaaa tgtgaaataa
    10861 gcaccaacaa catagacttt acaacacttc atgtttcata tcatggggtg tttttctatt
    10921 taaatcaaag cccatcaaaa aatctcacta ttcatcaggt taaaggaaac ctaatcatag
    10981 tgagattgtg aattatagta gagtttgtat cgcctcttca atttgttttg ggtctgtttt
    11041 tgaagaaaag cgttcaaaga cttgcccatc tcgaccgatg agaaacttag cgaaattcca
    11101 ttcgattcgt tttcctagtg ggccggattt ctggtctttt aaccagacat agagagggtc
    11161 tgcttcctta ccgttgacct taatcttggc aaaacgtggg aaggtggttt gaaaatgtag
    11221 gctacagaag gcgttgattt cctctgcgct gccgggtgct tgtcccataa actgattgca
    11281 agggaaatcc aatatttcga agccctgatc ttgatagcgt tcatagagtt cttgaagtcc
    11341 ctggtactgg ggcgttaaac cacatccagt agcagtgttg acaatcaaga gaactttgcc
    11401 acgatagcta tccaagggag ttgcttggtt gttttggttc aaaacggaaa aatcataaag
    11461 tgaagtcatg agggcctctt ttctttttct acattgtaac agtttttact tttttcgtcg
    11521 agtcggatgg aagatattgt tgaagaataa gccttcaata tgatagaaac cgtttacaaa
    11581 taactttaaa aatggtatga tttaattaaa ccggtttact tagttgctat aaatctctaa
    11641 tttgagattt agttcctatt gattttacaa tatgtttatt ggagtgtata catgcaaaca
    11701 aaaacaaaga agctcattgt gagtttgtct tcacttgttt tatcaggatt tttattaaac
    11761 cattatatga cagttggagc ggaagaaacg actacgaata ccattcagca aagccagaag
    11821 gaagttcagt atcagcaaag ggatacaaaa aatttagttg aaaatggtga ttttggtcag
    11881 acggaggacg gaagcagtcc gtggacagga agcaaagctc aggggtggtc agcttgggta
    11941 gaccagaaga atagtgcaga tgcctcaact cgagtcattg aggctaagga tggggctatc
    12001 actatctcaa gccatgagaa attaagggca gcgcttcacc gtatggttcc tattgaagct
    12061 aagaaaaagt ataaactgcg tttcaagatt aaaacagata ataaagtcgg gattgctaaa
    12121 gttcgtatca ttgaggaaag tggtaaggac aagcgattgt ggaattctgc aacgacgtca
    12181 ggaacaaagg actggcagac cattgaagca gactatagtc cgactttaga tgttgataaa
    12241 atcaagctgg agttattcta tgaaacagga actgggactg tttcctttaa ggatattgag
    12301 ctggtagagg tagcagacca gctttctgag gattctcaaa cagataaaca gcttgaggaa
    12361 aagattgatt taccaattgg aaaaaaacat gttttttctc ttgcggacta tacttataag
    12421 gtagaaaatc ctgacgttgc ttcagtcaaa aatggaattt tagaacctct taaggaaggg
    12481 acaaccaatg tcattgtcag taaagatggc aaggaagtga aaaagattcc tttgaagatt
    12541 ctagcctctg ttaaggatgc atacacagcc cgtttggatg actggaatgg catcatcgct
    12601 gggaatcaat actatgattc taaaaatgaa cagatggcca aattaaacca ggaattggaa
    12661 ggaaaggtag ctgatagcct atctagtatt tcaagtcagg cggaccgcac ctatttgtgg
    12721 gaaaaatttt caaattataa aacgtctgca aatctgactg ccacttatcg gaaattggag
    12781 gagatggcca agcaagtgac caatccttct tctcgttatt atcaagatga aactgtcgtt
    12841 cgaacagtca gggattccat ggaatggatg cataaacatg tctacaatag tgaaaagagc
    12901 attgttggga actggtggga ttatgaaatc ggtacacctc gtgccatcaa caataccttg
    12961 tctctgatga aagaatactt ctctgatgag aaaattaaaa aatatacaga tgtgattgaa
    13021 aaatttgtac cagatcccga acatttccga aagacgactg ataacccatt taaggctcta
    13081 ggtggaaact tagttgatat gggaagagta aaagtaatag ctggtttact gcgtaaggat
    13141 gatcaagaaa tttcttctac cattcgctcg attgagcaag tgttcaagtt ggtagaccaa
    13201 ggtgaaggtt tttatcaaga tggatcctat atcgaccaca ccaatgttgc ctatacgggt
    13261 gcttatggga atgttttgat tgatggcctg tctcaactgt tgccagtcat tcaaaagacc
    13321 aagagtccaa tcgataaaga taaaatgcaa accatgtacc actggattga taaatcgttt
    13381 gctcctttgc tggtgaatgg agagttgatg gatatgagtc gtggacgctc aatcagtcgt
    13441 gcaaatagcg aggggcacgt ggccgcagta gaagtactaa gagggattca ccgaatagcg
    13501 gatatgtctg aaggagaaac caaacaacgt ttgcagagtc ttgtgaagac cattgttcaa
    13561 tcggatagtt attatgatgt ctttaagaat ttgaagactt ataaggatat cagtttgatg
    13621 caatccttgt taagtgatgc aggagtcgca agtgttccaa gaacaagtta cctatttgcc
    13681 tttaacaaga tggataaaac agccatgtac aatgcagaga aagggtttgg atttggcttg
    13741 tcactctttt ccagtcgtac cttgaattac gaacacatga acaaggaaaa taaacgtggt
    13801 tggtatacga gtgatgggat gttctatctt tacaatggcg atttgagtca ctatagcgat
    13861 ggctactggc caacagttaa tccatataag atgcctggta caacagagac ggatgctaag
    13921 agagcggata gcgatacagg taaagtttta ccgtctgctt tcgttggaac gagcaaacta
    13981 gatgatgcca atgcgacagc aaccatggat ttcaccaact ggaatcaaac attgactgct
    14041 cataagagct ggtttatgct aaaggataag attgcctttt taggaagcaa tatccaaaac
    14101 acttcaacag atactgctgc aactacaatt gaccagagaa aactggaatc aagtgatcca
    14161 tataaagtct atgtcaatga taaagaagcc tcccttacag aacaagaaaa ggattatcct
    14221 gaaacccaaa gtgtcttttt cgaatcgtcc gattcgaaaa agaatattgg ttactttttc
    14281 tttaagaaga gttcaatcag tatgagtaag gctttgcaaa agggagcctg gaaggatatc
    14341 aatgaaggac agtcagacaa ggaagttgaa aatgaatttc ttacgattag tcaggctcat
    14401 aagcaaaatg gagattctta tggctatatg ctcattccta acgtggatcg tgccaccttc
    14461 aatcaaatga taaaagagtt agaaagtagc ctcatcgaaa ataacgaaac ccttcagtct
    14521 gtttatgatg ccaaacaagg agtttggggc attgtgaaat atgatgattc tgtctctact
    14581 atttccaacc aattccaagt tttgaaacgt ggagtctata ctattcgaaa agaaggggat
    14641 gaatataaga ttgcctacta taatcctgaa acccaggaat cagctccaga tcaggaagtc
    14701 tttaaaaagc tagagcaagc agctcagcca caagtacaga attcaaaaga aaaggaaaaa
    14761 tctgaagagg aaaagaacca ttcggatcaa aagaatctcc ctcagacagg agaaggtcag
    14821 tcaatcttgg caagtctagg gttcttgcta cttggggcgt tttatttatt ccgtagagga
    14881 aagaacaact aatttgttca tcatctagat gaattacatg aaactgtggc aaatagaaaa
    14941 aatccgaaga aggccaaata tcttcggatt tttcttttaa aaagggataa gttgatactt
    15001 atcctttttt acttcattat gtgactatag cgttttgaaa ctagaatagg acgtcataac
    15061 tgctaaaaga tttctataaa ttcatttgat tttcctaatc aatttgttcg tatcctattt
    15121 cactccacta tattagtccg tctcgctccg tgaggtgcga gacaaaacaa ccacccgcta
    15181 tacgggtgcg cgtcgaaggt tataccaaaa aaactccaaa cgcgatacaa taaaggtgtt
    15241 caatccactt gtaaagcgaa aggagaaaaa atatggcaca aaagactcat agtttatctc
    15301 acacaaagtg gaagtgttct atcatattgt gttcacccct aagtatagac gaaaagtcat
    15361 ctataatcaa tatcgaagta gtttaggcga aatattttat cgcttgtgta gttataaagg
    15421 tgttgaaatg atcgagggtc acttaatgcc agaccatgta cacatgttag tcagtattcc
    15481 actaaggcta agtgtttcaa gttttatggg gtatttaaaa ggcaaaagtg cactcatgat
    15541 gtttgacaaa cacgccaatc tcaagtacaa gtttgggaat cggcatttct gggcggaagg
    15601 ttattatgta agtccagtag ggcttaatga agccacaatt aagaaatata gtcaagatta
    15661 aagaaattat cgagtggatg atttcttcac gagtatgaaa atttgagaac gagtaaagca
    15721 tgatatatag taaaatgaaa taagaacagg acaaaatcga tcaggacagt caaatcgatt
    15781 tttaacaatg ttttagaagt agatgtgtac tattccagtt tcaatctact atagcactag
    15841 ataaattgag tgtaaaagaa tatgaggatc cctttaggga tagtggtaag taataccaaa
    15901 gtctcttaaa gaggcaagtg acgagtcaag agcaataagg cttgaacaac gtgaaagcca
    15961 gcgtctttag gcgctggctg atgatttggg cttatagctc tgagataaac cacccgttag
    16021 acgggtagtt atgattttat ctgagtgtaa tatactgttg ggcaatctcg ctgatgcggt
    16081 caaagttgcc ttgggaagcg agtttattga gttcgccacc aattccaacg gcatctgcac
    16141 cagcagcgaa ccattgaggg atgttgttta ggccgactcc tccggttacc attacggaaa
    16201 cttgtgggat tggtgccttg actgcagaga tatatgctgg actgagagta ctacctggga
    16261 agagtttgat gatttcacta ccggcttcaa gtgcagtcgt gatctctgtg agggtaatac
    16321 agcctggaat gtacggtgtg ctgtagagat tgcacatttt cgcagtttca gcatggaaag
    16381 atggagaaac aacgtaattt gctccagcta gaatggcatc tctagcagtt acggcatcaa
    16441 gcacagtacc tgcaccgata caaacactct gatcgtcctg atacaagtct acaagttcct
    16501 tgatgatttg tcctgcatac tgattggtat aggcgatttc aatagctttg ataccgccct
    16561 tgatacaagc aatcgaggct tgtagtcctt cttcctttgt atttcctcga atgacagcga
    16621 caattttctg tttttttagt tcaataatcg tatctgattt ggtcatgtaa ttctcctaac
    16681 gaatgatatc ttgtgcattt gccagtaaat tttcaatact agttgcggaa gtggagagat
    16741 ggtctcctgg aagagtgcat ttgagagttg cgctcgcaac tgcaaagtca atggtagttt
    16801 ttagggagga atgatggagt agttggtaaa gggcaccaga tataaaggca tccccgctac
    16861 caattcgttg atagactgca gtttttagtt ggacagactc ttcaaatcgt tcttccagag
    16921 cataggcttg atagacattt ttgtcttgct catcactaga tcggagggta tggaaaatgg
    16981 ccttgaaacc ataggcttct tttaaaagtc gcatgcgatt ttccacctct tctaggctag
    17041 cactgtctct tggaaacatc tctagatttt ggtcatcaat catgagagga tcaataccga
    17101 agcaatagtc agtaaaacgt gcaaacttag aaaattcata cttggcttct aggactgaaa
    17161 tcatctttgt tctcagattg agatccattg aaacgacaat tcctcggcgc ttggcttctt
    17221 ccaagagtag gagaaggatc gcacggacct cttgaccgat agctatggtg attccactaa
    17281 aatgaaaatg gctaatcccc tgaaagagag aatccatatc tagcatgttt ggccgaatct
    17341 ggctgatact cgtatgctta cgatcgtaga aaacttcact ttgacgacaa ccaaagccgt
    17401 tctccaaata gtagaggccg attcgatcgc caagccgaca gattgaactg gtatcgattt
    17461 ggtgctgttt caagaatgtg agaaaacgat ctccaatctc gttggcaggg agtgcggtaa
    17521 agactttcgt tgagataccc agggcttgca aattacaagc gatgttaatt tctgatccgc
    17581 caaaataagt cgaactggca acatgatcgc cgatactggt ggcatctaat ggtgagattc
    17641 gaattaatgg ttcgccaaac agtaatattt tcgtcatcca ttagttcctt tctggtttag
    17701 aatagcttta cttagctaat acttctttca aataagcagc gacttcatca tcttggcagt
    17761 tttcaaagaa gtattcttgg aagtatttgc cagagatggt gtctttgagg aagtcttggt
    17821 cgattgtttt aaggatggtc atcaaatcat tgtgggtgat ttgttttacc tcgtttaaga
    17881 tacgagcgtt gcgttgttca gggattacac gttctcttgg gtagccaccg cccatttctt
    17941 cagcaaataa gcgttcaaac atcaatttga gggtcagttc tgccccccag ccaaatcctt
    18001 tggcataagg gatagacaag gcgttaccac cattgatttg agaataaagg taagcgtcag
    18061 ttgggtccac tgctagacca cagacaatac cagggaagct gtttaaagca agcatagccc
    18121 ctacacccgt accacagccg gtaacaacaa agtcaactgc ctttgtattt aaaaggatgg
    18181 cagccattag tccgttctgc acataagtta attgactttc tccttcttct ccacgcatac
    18241 catagttaaa taattggtag ccttttttat ctgtcgcttc ttttagacta tcgtaaataa
    18301 tgtgattctt gctagcttga ctattttcat tgattaatgc gattttcata agatcttctt
    18361 tctattttta ctcaggttgt tttccgatgt aggctaagat accgccatct acatatagga
    18421 tgtggccatt gacaaaattg ctggcatcac tagcgagaaa gacagcaggg cccatcaaat
    18481 cttcaggatt tccccaacgt gcagcaggtg tttttgcaat gatgaactgg tcaaatgggt
    18541 ggcgagaacc atcttcttgc aactcacgaa gaggtgctgt ttgaggagtg gcaatataac
    18601 ccggtccaat tccgttacat tggatattgg ctccaccgta ttcagacgca atgttgcggg
    18661 tcaacatttt caagccccct ttagcagcag cataagcgct aactgtttca cgtcccagtt
    18721 cgctcatcat cgaacaaata ttgataatct ttccatgccc tttctttatc atagaaggaa
    18781 taactgcctt tgaaacgata aatggtgcgt ttaagtcaat atcgatgacc ttacggaaat
    18841 cagcggcgct catttcgcac attggaactc ggcggataat accagcgtta ttaacgagga
    18901 tgtcaatgac accaacctct tgttcgattt gcttgaccat ggcttggata ccgtcctcgt
    18961 ctgtcacgtc acagacatat ccatgggctt cgatgccaac ttcacgataa gcttcaatcc
    19021 ctttattgac cagatcttga ttgatatcgt taaagacaat agtagcgccg gcttcagcgt
    19081 aggatttggc aatagcaaat ccaattccat aagaagcgcc ggtgatgaga gcaatttttc
    19141 cttttaaaga aaactgctca attgagaatg atgtatttgt catttgatac ttcctttcaa
    19201 atttgttaag acttctctat aaccaaatta tattctagta aaccggtttt gtcaataaat
    19261 aaatattttt atttataaaa agatttgttt tcctaaaaaa acggaagatt ttgaaatttc
    19321 tgtctattaa actggttaaa aagataatga aagcgctaat atttttttaa aaaaactatt
    19381 gacaagataa aaataaagga ttacaatggg gaatataaag taaaccggta aacctaaaca
    19441 agaaaggaga aaagatgaaa attgtacttg tagggcatgg acattttgct acagggattt
    19501 atagttcttt acaattgatt gcaggtaatc aagaaaatgt ggaggcgatt gactttgtgg
    19561 aaggaatgtc agcagatgaa ctcaagcaaa aaatcttact tgcaatttca aatgaagaag
    19621 aagttttaat cctaagtgat ctcttgggag gatcgccatt caaggtttct tctaccataa
    19681 tgggagaaaa tccagtcaaa acaatgaatg ttctctcggg tttgaactta gccatgttaa
    19741 tggaagcagt ctttgctaga atggctcata gctttgatga ggttgttaat aaatcagtag
    19801 tggcggccca gggcggagtc gtaaatggta aagaattgtt ttcaacggat gcagaggaag
    19861 aggaagaaga tttcgaatcg ggtatttaaa gggtaaaaga atgataaaaa aggttacgat
    19921 tgaaaaaata aaatcgcctg agcgcttctt agaagtacca cttctgacga aagaagaagt
    19981 cggccaggca atcgataagg ttattcggca gttagaactc aaccttgact atttcaagga
    20041 agatttcccg acgccagcta cctttgataa tgtctatcca atcatggata acacggaatg
    20101 gaccaatggt ttctggacag gagaactgtg gttggcttat gaatacagtc aacaggatgc
    20161 atttaaaaac atcgctcata aaaatgttct ttctttcctg gatcgtgtca ataagagagt
    20221 agaattggat caccatgatc tcggcttctt gtacacaccg tcttgtatgg ctgaatataa
    20281 gataaatgga gatggagagg ctagagaagc aaccttgaaa gctgcagata agttgattga
    20341 acgctatcaa gaaaaaggtg gttttattca agcttgggga gacttgggca agaaagagca
    20401 ttaccgtttg attatcgact gcttgctcaa tatccaactc ttattctttg cttatcaaga
    20461 aacaggtgat caaaaatact acgatattgc agaaagccat ttctatgctt cagctaataa
    20521 tgtaatccgt gatgacgctt cgtccttcca caccttctat tttgatcctg agacaggtca
    20581 accctttaaa ggtgtaacga gacaagggta tagtgatgat tcatgctggg cacgtggtca
    20641 atcatgggga gtctatggta ttcctttgac ttatcgtcac ttaaaagacg agtcctgctt
    20701 tgacttgttt aagggtgtga ccaattattt cttgaatcgt ctgccaaaag atcatgtgtc
    20761 ctattgggat ttgattttta atgatggtag tgatcaatca cgagattctt cagcaacagc
    20821 tatcgccgtc tgtgggattc atgaaatgct aaaacatctc ccagaggtgg atgctgacaa
    20881 agatatttat aaacatgcta tgcatgccat gcttcgttcc ttgatcgaac attatgcaaa
    20941 tgatcaattt acccctggtg ggacaagtct cctccacggt gtgtactcat ggcattcagg
    21001 taaaggagtg gatgaaggca atatctgggg tgactactat tacctagaag cccttatccg
    21061 tttctacaaa gactggaacc tatattggta ggaggagaaa tatgacaatg ccaaatatta
    21121 ttatgacccg tatcgatgaa cggttgattc atggacaagg acaactttgg gtaaaatacc
    21181 taggttgtaa tacggtcatt gttgccaatg acgaagtaag cacggacaag atgcaacaaa
    21241 ctctgatgaa aacagttgtg ccagactcag ttgccatgcg tttcttccct ttgcaaaagg
    21301 tgattgatat cattcacaag gctaatcctg ctcaaacgat ctttatcgtt gtaaaggatg
    21361 taaaggacgc tttaaccttg gtagaaggtg gtgtccctat caaagaaatc aatattggga
    21421 acattcacaa tgcccctggt aaagagcaag tgacacgctc catcttcctg ggtgaagagg
    21481 acaaggcagc cctcaaggaa ttaagccaaa ctcatcaagt aacatttaat acgaaaacaa
    21541 ctccaacagg aaatgatgga gctgttcaag tcaacattat ggactatatt taaaagagga
    21601 gatcgttatg tcgattaatg tatttcaagc gattttaatt ggattatgga cagctttctg
    21661 ttttagtgga atgctgttag gaatttacac caatagatgt attgttctgt catttggtgt
    21721 cggaattatt ctaggtgatc tgcctactgc tcttgcaatg ggagctattg gtgaattggc
    21781 ttatatggga ttcggtgttg gtgctggagg tactgttcca ccaaacccaa tcggacctgg
    21841 tatctttggt accttgatgg ctatcactag tgctggtaaa gtcagtccag aagcggctct
    21901 tgccctctct actccgattg ctgtggcgat tcaattctta caaactttcg cctacactgt
    21961 acgtgctggt gcgcctgaaa cggcgatgaa gcacttgaaa aaccataatt tgaagaaatt
    22021 caagttcact ctaaatgcaa caatttggtt gtttgccttt attggattta ccttgggttg
    22081 cttgggtgcc ctttcaatgg ataccttgtt gaaactcgta gactacattc caccggtatt
    22141 acttacaggt ttgacagttg ctggtaaaat gctcccagct atcggttttg cgatgatctt
    22201 gtcagtgatg gctaagaaag agttgattcc ctttgtcttg ttgggatatg tttgtgcagc
    22261 ttatctaaac atcccaacaa ttggtattgc aattgtaggt actatctttg ctttgattga
    22321 attttataac aagccaaaaa cagcggatca tgtggtagag gaggaagcac acgatgactg
    22381 gatctaacaa attaacaaaa cgtgattatc ttaaaacgtc tttgcgggca ttcttttgtc
    22441 aaaatggatt taactatagt aactatcaag ggttgggata tgccaatgtg atgtatcctg
    22501 ctttgaaaaa acactatgga gaggatcagg aaggtttcta ccaagccttg gaagaaaact
    22561 gtgaattcta taataccaac ccacacttcc tgccttttat taccagcttg catcttgtaa
    22621 tgttggaaaa tggtcgacca acaaaagaaa cacgtagcat caagatggcc ttgatgggac
    22681 cattggcagg tattggggat tctctttctc aattctgttt agctccattg ttctcaacca
    22741 tcgcagcttc gtttgctcaa gaaggcttgg ttgtcggtcc aatcttgttc ttccttgcga
    22801 tgaatacgat tttaacagcg attaaattgt caactggtct gtatggatac aaactaggaa
    22861 cgactgtgat tgataaacta agtgagcaga tggcaacgat ttctcgtatt gccaatatta
    22921 ttggtgtaac cgtaattgct ggtttggcag cgacatctgt taagattatg gtgccgatca
    22981 cctttgctgc aggggaagtt aaagcagacg ctaaacaaag tatcgtaagt attcagggaa
    23041 tgcttgataa ggttgctcca gctcttctac cagccctatt tacactttta gtttactact
    23101 tgatcaaaga aaagaaatgg acaacagata aactcgttat tttaacagtt atcatcggaa
    23161 ttatcggaag ctggcttaag attctagctt aatggataca acattgtttt atggaatagt
    23221 gattgtcttg gcagtgagcc cccttttact gtcaagcttt cattctattc gtcagcaaaa
    23281 gttgcttcgc aaacagatgg agcaacgaaa agagtattta gcttctttaa catctggtga
    23341 tgaagtgttg ttattgtctg gaattcatgg aaaaatcatt tctatcaaag atgacttggt
    23401 ctccttgcag attgcaaaag gtgtggtcat ctatgtagaa aaggaaagtg taatgggaaa
    23461 gacaaaagaa ctgcttttta agtagttctt tttctggtaa tagataatga aagaagaaag
    23521 aagacaattt tttgaaagaa ttgatgggga ccaatatcgt gattatatct tgtcccgctg
    23581 ttcaaaagac tatgagaaag tcaagagttc ccttgagcgc ttgatggaca atcgttttat
    23641 gtttgatagt ccttgggata tggaaccttg ttcaaaaatc catcaaatcc agccgatggt
    23701 gtggaatcaa gtatttgaag atgatccaga atgggcttat atgctcaatc gacaagaata
    23761 tctcctgcag tttatgatag ggtatctagt agaaggagat aaggtctata ttcaaaagtg
    23821 taagttcttt ctatttgact ggattgagca ggtgagagaa tttcgtcctc aatctttgat
    23881 gactagaacc ttggatacgg gtattcgttc ctttacttgg ttgaaactac tcttgctcct
    23941 cttgaaattt gacttgctag aggaggaaga actagagaaa attttggtca gtctagaaaa
    24001 gcagattgac tttatgaaaa gccattatcg cgccaagtac acccttagta actgggggat
    24061 tttacaaacg attccgatac ttgcaaccta tcatttcttt tcagataaga tggacctaga
    24121 agaagcttac cattttgctt caaaggagtt gaaacagcag atcgagacgc agattttaga
    24181 ggatggaagt cagtttgaac agtcgattct ctatcatgta gaggtttata aagccttgct
    24241 ggacttgtgt ctcttgcttc cggacttgca agataacttt caagagctgc tggaaaagat
    24301 ggcgacttac attcaaatga tgacaggtct agatggacgg accttggctt ttggtgatag
    24361 cgattctaca gaaacgacag agattttgag cctgtctgct atggttttga acaaggaaga
    24421 cctttttaac ggtctggatg ttaaagtcga tttacttagc ctcctgttcc tggggcgaga
    24481 aaaggtcaag cgactgcagg aatttgaaaa gagagcttgg cagcctaagt tcaggagctt
    24541 tgaagattct gggcatgttt gcattaagga tgaacatcgt tatctatttt ttaaaaacgg
    24601 tccgctggga agtgcccata gccatagtga cgagaatagt ttttgcttac agtatcaagg
    24661 ccaaccgatt ttcatagata ctgggcgtta ttcttatcgg gaggtagatg aacgttatct
    24721 cttaaagagt gcttggagtc attcgacctg tatagtagat gggaaagctc cagaaaggat
    24781 cgtgggatcc tgggaatatg aatactatcc tcactccctg ttttgtcacc acaaagaaag
    24841 agagggagtg cattatattg agggggcgta tttgtcagca gaacctgatt tgccttatct
    24901 tcacaagaga aaaatcctca tgttggcaga ggatgtatgg ctcttggtag atgatatcag
    24961 gtgtcaaggt cagcatgagg cgttgactca gtttatcctt gacaaggatg tgacctatca
    25021 agatgggaaa atcaatcagt tgagactatg gagtgaagtt gattttgatt tggaagatac
    25081 catcatttct cctaaataca atgagcttga aagaagtagc aaactcacca agcgccaatt
    25141 ctttgagaat cagatgctgg attataccat cattgcgcat gagagttttg aaatcatccg
    25201 tcattctgtc taccagacag atgatcgtga agtggaaaat gctctggctt ttgaagtgaa
    25261 aaatgacgaa acagacaagc tgattctgtt attaagcgag gatattggtg taggtgaaaa
    25321 attgtgcctc gttgacggaa caaaaatgcg tggaaaatgt ctagtatatg ataaaataaa
    25381 tgagagaatg attcgcttgc agtgctagaa ataggcattt tgaatagtga atatgttata
    25441 atgagtatta gtaggaggtg ttttagattg gagaagaaac tgaccataaa agacattgcg
    25501 gaaatggctc agacctcgaa aacaaccgtg tcattttacc taaacgggaa atatgaaaaa
    25561 atgtcccaag agacacgtaa aaagattgaa aaagttattc atgaaacaaa ttacaaaccg
    25621 agcattgttg cgcgtagctt aaactccaaa cgaacaaaat taatcggtgt tttgatcggt
    25681 gatattacca acagtttctc aaaccaaatt gttaagggaa ttgaggatat cgccagccag
    25741 aatggctacc aggtaatgat aggaaatagt aattacagcc aagagagtga ggaccggtat
    25801 attgaaagca tgcttctctt gggagtagac ggctttatta ttcagccgac ctctaatttc
    25861 cgaaaatatt ctcgtatcat cgatgagaaa aagaagaaaa tggtcttttt tgatagtcag
    25921 ctctatgaac accggactag ctgggttaaa accaataact atgatgccgt ttatgacatg
    25981 acccagtcct gtatcgaaaa aggttatgag cattttctct tgattacagc ggatacgagt
    26041 cgtttgagta ctcggattga gcgggcaagt ggttttgtgg atgctttaac agatgctaat
    26101 atgcgtcacg ccagtctaac cattgaagat aagcatacga atttggaaca aattaaagaa
    26161 tttttacaaa aagaaatcga tcccgatgaa aaaactctgg tatttatccc taactgttgg
    26221 gccctacctc tagtctttac cgttatcaaa gagttgaatt ataacttgcc acaagttggg
    26281 ttgattggtt ttgacaatac ggagtggact tgcttttctt ctccaagtgt ttcgacgctg
    26341 gttcagccct cctttgagga aggacaacag gctacaaaga ttttgattga ccagattgaa
    26401 ggccgcaatc aagaagaaag gcaacaagtc ttggattgta gtgtgaattg gaaagagtcg
    26461 actttctaaa atgaaggaaa atgacttgca atctctgtta agaaataaaa taatcccacc
    26521 tagaacaagc taggtgggat tatttgccta tgaaatgaga aattatggga gcaagctcct
    26581 aaatcaactg tttttgatct acttctttaa ctacttgata aaagttatag aagtaggtca
    26641 aacttgaaat gatggttacg actaggaata ttgaaaattt ccattggaca gggttggtta
    26701 aaagttgtgg aaaggatatg aggagaaaga agagggctgc gttgaggaca ggtatccgtt
    26761 ttgattgtat tttctcaagt cctttattga gcgcaggaag aaagaggagt aggagtagta
    26821 aaactgtatg agaaacagct cctgaaataa gggcgcagaa aaggaaaata ctgataaaaa
    26881 catgaatgat cagtagtcta gctagtgatt tcataaggca cctcctaatc ctggtctttt
    26941 ttagctcttg caatacgaag tgagtcgaca atatgtatca tcactccgaa aaagaaagct
    27001 cccagtatag ttttaaaaat atgttttgta tttagaagag aactgataaa attgggattt
    27061 tcacttgtta gggtatcaat gagtggaatt ataaaaaata tcactgttcc ataaatcgaa
    27121 cctgctttca gaccaggata acgtaactgt ttcttttctt ttttcatgag tttgctcctt
    27181 ttttaaaaat cttcctccca aaagagactg ttgaggtcag tttggaggct gcgggcgaga
    27241 ttgagacaga gttccaaggt tggattgtac ttgtcgtttt caatcatatt gatagtctgt
    27301 ctcgagacac cgatatcctt ggcgagctcg agctgggaaa tacccaattc cttgcgaaat
    27361 tctttcacac gattcatctg ttcttctttc tgatttatgt cgtatatatt tgactatatt
    27421 atagtctttt aaacataaag tgtcaagtat ttttgacata ttttttgaag aaatagtagt
    27481 ctccttgtcc tatttgtctg acaagtgcaa gctggtcgga tttgtggtaa aatagataag
    27541 atatgacaaa agaatttcat catgtaacgg tcttactcca cgaaacgatt gatatgcttg
    27601 acgtaaaacc tgacggtatc tacgttgatg cgactttggg tggagcaggc catagcgagt
    27661 atttattaag taaattaagt gaaaaaggcc atctctatgc ctttgaccag gatcagaatg
    27721 ccattgacaa tgcgcaaaaa cgcttggcac cttacattga gaagggaatg gtgaccttta
    27781 tcaaggataa cttccgtcat ttacaggcac gtttgcgcga agctggtgtt caggaaattg
    27841 atggaatttg ttatgacttg ggagtgtcta gtcctcaatt ggaccagcgt gagcgtggtt
    27901 tttcttataa aaaggatgcg ccactggaca tgcggatgaa tcaggatgct agtctgacag
    27961 cctatgaagt ggttaatcat tatgactatc atgacttggt tcgtattttc ttcaagtatg
    28021 gagaggacaa attctctaaa cagattgcgc gtaagattga gcaagcgcgt gaagtgaagc
    28081 cgattgagac aacgactgag ttagcagaga ttatcaagtt ggtcaaacct gccaaggaac
    28141 tcaagaagaa ggggcatcct gctaagcaga ttttccaggc tattcgaatt gaagtcaatg
    28201 atgaactggg ggcggcagat gagtccatcc agcaggctat ggatatgttg gctctggatg
    28261 gtagaatttc agtgattacc tttcattcct tagaagaccg cttgaccaag caattgttca
    28321 aggaagcttc aacagttgaa gttccaaaag gcttgccttt catcccagat gatctcaagc
    28381 ccaagatgga attggtgtcc cgtaagccaa tcttgccaag tgcggaagag ttagaagcca
    28441 ataaccgctc gcactcagcc aagttgcgcg tggccagaaa aattcacaag taagagggaa
    28501 aaagatggca gaaaaaatgg aaaaaacagg tcaaatacta cagatgcaac ttaaacggtt
    28561 ttcgcgtgtg gaaaaagctt tttacttttc cattgctgta accactctta ttgtagccat
    28621 tagtattatt tttatgcaga ccaagctctt gcaagtgcag aatgatttga caaaaatcaa
    28681 tgcgcagata gaggaaaaga aaaccgaatt ggacgatgcc aagcaagagg tcaatgaact
    28741 attacgtgca gaacgtttga aagaaattgc caattcacac gatttgcaat taaacaatga
    28801 aaatattaga atagcggagt aagatatgaa gtggacaaaa agagtaatcc gttatgcgac
    28861 caaaaatcgg aaatcgccgg ctgaaaacag acgcagagtt ggaaaaagtc tgagtttatt
    28921 atctgtcttt gtttttgcca tttttttagt caattttgcg gtcattattg ggacaggcac
    28981 tcgctttgga acagatttag cgaaggaagc taagaaggtt catcaaacca cccgtacagt
    29041 tcctgccaaa cgtgggacta tttatgaccg aaatggagtc ccgattgctg aggatgcaac
    29101 ctcctataat gtctatgcgg tcattgatga gaactataag tcagcaacgg gtaagattct
    29161 ttacgtagaa aaaacacaat ttaacaaggt tgcagaggtc tttcataagt atctggacat
    29221 ggaagaatcc tatgtaagag agcaactctc gcaacctaat ctcaagcaag tttcctttgg
    29281 agcaaaggga aatgggatta cctatgccaa tatgatgtct atcaaaaaag aattggaagc
    29341 tgcagaggtc aaggggattg attttacaac cagtcccaat cgtagttacc caaacggaca
    29401 atttgcttct agttttatcg gcctagctca gctccatgaa aatgaagatg gaagcaagag
    29461 cttgctggga acctctggaa tggagagttc cttgaacagt attcttgcag ggacagacgg
    29521 tattattacc tatgaaaagg atcgtctggg taatattgta cccggaacag aacaagtttc
    29581 ccaacgaacg atggacggta aggatgttta tacaaccatt tccagccccc tccagtcctt
    29641 tatggaaacc cagatggatg cttttcaaga gaaggtaaaa ggaaagtaca tgacagcgac
    29701 tttggtcagt gctaaaacag gggaaattct ggcaacaacg caacgaccga cctttgatgc
    29761 agatacaaaa gaaggcatta cagaggactt tgtttggcgt gatatccttt accaaagtaa
    29821 ctatgagcca ggttccacta tgaaagtgat gatgttggct gctgctattg ataataatac
    29881 ctttccagga ggagaagtct ttaatagtag tgagttaaaa attgcagatg ccacgattcg
    29941 agattgggac gttaatgaag gattgactgg tggcagaatg atgacttttt ctcaaggttt
    30001 tgcacactca agtaatgttg ggatgaccct ccttgagcaa aagatgggag atgctacctg
    30061 gcttgattat cttaatcgtt ttaaatttgg agttccgacc cgtttcggtt tgacggatga
    30121 gtatgctggt cagcttcctg cggataatat tgtcaacatt gcgcaaagct catttggaca
    30181 agggatttca gtgacccaga cacaaatgat tcgtgccttt acagctattg ctaatgacgg
    30241 tgtcatgctg gagcctaaat ttattagtgc catttatgat ccaaatgatc aaactgctcg
    30301 gaaatctcaa aaagaaattg tgggaaatcc tgtttctaaa gatgcagcta gtctaactcg
    30361 gactaacatg gttttggtag ggacggatcc ggtttatgga accatgtata accacagcac
    30421 aggcaagcca actgtaactg ttcctgggca aaatgtagcc ctcaagtctg gtacggctca
    30481 gattgctgac gagaaaaatg gtggttatct agtcggggta accgactata ttttctcggc
    30541 tgtatcgatg agtccggctg aaaatcctga ttttatcttg tatgtgacgg tccaacaacc
    30601 tgaacattat tcaggtattc agttgggaga atttgccaat cctatcttgg agcgggcttc
    30661 agctatgaaa gactctctca atcttcaaac aacagctaaa gctttggagc aagtaagtca
    30721 acaaagtcct tatcctatgc ctagtgtcaa ggatatttca cctggtgatt tagcagaaga
    30781 attgcgtcgc aatcttgtac aacccatcgt tgtgggaaca ggaacgaaga ttaaaaacag
    30841 ttctgctgaa gaagggaaga atcttgcccc gaaccagcaa gtccttatct tatctgataa
    30901 agcagaggag gttccagata tgtatggttg gacaaaggag actgctgaga cccttgctaa
    30961 gtggctcaat atagaacttg aatttcaagg ctcgggctct actgtgcaga agcaagatgt
    31021 tcgtgctaac acagctatca aggacattaa aaaaattaca ttaactttag gagactaata
    31081 tgtttatttc catcagtgct ggaattgtga catttttact aactttagta ggaattccgg
    31141 cctttatcca attttataga aaggcgcaaa ttacaggcca gcagatgcat gaggatgtca
    31201 aacagcatca ggcaaaagct ggcacgccta ccatgggagg tttggttttc ttaattactt
    31261 ctgttttggt tgctttcttt tttgccctat ttagtagcca attcagcaat aatgtgggaa
    31321 tgattttgtt tatcttggtc ttgtatggct tggtcggatt tttagatgac tttctcaagg
    31381 tctttcgtaa aatcaatgag gggcttaatc ctaagcaaaa attagctctt cagcttctag
    31441 gtggaattat cttctatctt ttctatgagc gcggtggcga tatgctttct gtctttggtt
    31501 atcaagtgca tctagggatt ttctatattg tcttcgctct tttctggcta gtcggttttt
    31561 caaacgcagt aaacttgaca gacggtgttg acggtttagc tagtatttcc gttgtgatta
    31621 gtttgtctgc ctatggagtt attgcctata tgcaaggtca gatggatatt cttctagtga
    31681 ttcttgccat gattggtggt ttgctcggtt tcttcatctt taaccataag cctgccaagg
    31741 tctttatggg tgatgtggga agtttggccc taggtgggat gctggcagct atctctatgg
    31801 ctctccacca agaatggact ctcttgatta tcggaattgt gtatgttttt gaaacaactt
    31861 ctgttatgat gcaagtcagt tatttcaaac tgacaggtgg taaacgtatt ttccgtatga
    31921 cgcctgtaca tcaccatttt gagcttgggg gattgtctgg taaaggaaat ccttggagcg
    31981 agtggaaggt tgacttcttc ttttggggag tgggacttct agcaagtctc ctgaccctcg
    32041 caattttata tttgatgtaa gaatggcacc ctgatgtttc agggtgtttt tgtgtttaaa
    32101 tacacaatga aaatcaaaga acaaactaga aagctaactt taggctgctc aaaacatagt
    32161 agtttgaaac tagaatagta cacatctact tctaaaatat tgttagaaat cgatttgact
    32221 gtcctgatcg atttgtcctg ttcttatttc attttaatat acagttttga gatggctgat
    32281 agaactgacg aagtcagctc aaaacacggt tttgaggttg tagacaaggc gaagctgatg
    32341 tggtttgaag aggttttcga agagtgtaaa aaaatattgg tcagttaaag tcaaaactct
    32401 tgaccttttc tgaccaatgt agtatattat gaacgtaagg taaatgaaag ccttactaga
    32461 acacttattt aaagtaaaat agaaagaggt gggtctatgt ttcatctaga aatcttcaga
    32521 agtaaagata gtctactcct gcttgaaaaa gaaaaaccag aaatagtacg tagggtagcg
    32581 atctagctag tctaaatttt ttaaaacaat ggtcaaagat agtcaatatc agtaatcata
    32641 actaagtaaa caaaaagagg taaagaatat gaataacaac tttaataatt ttaataacat
    32701 ggatgattta tttaaccaat tgatgggtgg tatgcgagga tacagttctg aaaatcgccg
    32761 ttacttaatt aatggacgcg aagtcacacc tgaggaattt gctcactatc gtgcgactgg
    32821 tcaattacta ggaaatgcag aaactgatgt gcaaatgcca caacaggcat caggtatgaa
    32881 acaagacggt gtccttgcaa aactaggtcg aaacttaaca gcagaagcgc gtgagggcaa
    32941 gttggatcct gttatcggac gaaacaagga aattcaagaa acatctgaaa tcctctcacg
    33001 ccgcaccaag aacaatcctg ttttggtcgg agatgcaggt gttggtaaga cagcagttgt
    33061 cgaaggtcta gcgcaagcca ttgtgaacgg agatgttcct gctgctatca agaacaagga
    33121 aattatttct attgatatct caggtcttga ggctggtact caataccgtg gtagctttga
    33181 agaaaatgtc caaaacttag tcaatgaagt gaaagaagca gggaatatta tcctcttctt
    33241 tgatgaaatt caccaaattc ttggtgctgg tagcactggt ggagacagtg gttctaaagg
    33301 acttgcggat attctcaagc cagctctctc tcgtggagaa ttgacagtga ttggggcaac
    33361 aactcaagac gaataccgta acaccatctt gaagaatgct gctcttgctc gtcgtttcaa
    33421 cgaagtgaag gtcaatgctc cttcagcaga gaatactttt aaaattcttc aaggcattcg
    33481 tgacctctat caacaacacc acaatgtcat cttgccagac gaagtcttga aagcagcggt
    33541 ggattattct gttcaataca ttcctcaacg tagcttgcca gataaggcta ttgaccttgt
    33601 cgatgtaacg gctgctcact tggcggctca acatccagta acagatgtgc atgctgttga
    33661 acgagaaatc gaaacggaaa aagacaagca agaaaaagca gttgaagcag aagattttga
    33721 agcagctcta aactataaaa cacgcattgc agaattggaa aagaaaatcg aaaaccacac
    33781 agaagatatg aaagtgactg caagtgtcaa tgatgtggct gaatctgtgg aacgaatgac
    33841 aggtatccca gtatcgcaaa tgggagcttc agatatcgaa cgtttgaaag atatggctca
    33901 tcgcttgcaa gaaaaggtga ttggtcaaga taaggccgta gaagttgtag ctcgtgctat
    33961 ccgtcgtaac cgtgctggtt ttgatgaagg aaatcgccca atcggcagct tcctctttgt
    34021 agggtctact ggggttggta agacggagct tgctaagcaa ttggcactcg atatgtttgg
    34081 aacccaggat gcgattatcc gtttggatat gtctgaatac agtgaccgca cagctgtttc
    34141 taagctaatt ggtacaacag caggctatgt gggttatgat gacaatagca ataccttaac
    34201 agaacgtgtt cgtcgcaatc catactctat cattctcttg gatgaaattg aaaaggctga
    34261 tcctcaagtt attacccttc tcctccaagt tctagatgat ggtcgtttga cagatggtca
    34321 aggaaataca gtaaacttca agaacactgt cattattgcg acctcaaatg ctggatttgg
    34381 ctatgaagcc aacttgacag aagatgcgga taaaccagaa ttgatggacc gattgaaccc
    34441 cttcttccgt ccagaactcc tcaaccgctt taatgcagtc atcgagttct cacacttgac
    34501 taaggaagac ctttctaaga ttgtagattt gatgttggct gaagttaacc aaaccttggc
    34561 taagaaagac attgacttgg tagtcagtca agcggctaaa gattatatca cagaagaagg
    34621 ttacgacgaa gtcatggggg ttcgtcctct ccgtcgagtg gttgaacaag aaattcgtga
    34681 taaggtgaca gacttccact tagatcattt agatgctaaa catctggaag cagatatgga
    34741 agatggcgtt ttggttattc gtgagaaagc ctaagataga attttgagga taaaaaagaa
    34801 ggagccagct gaaaaaaact ggttcctttt gaggtacgac gggcatgtcg tacagtaggt
    34861 tgaaactaga atagtacaca tctacttcta aaatattgtt agaaatcgat ttgactgtcc
    34921 tgattgattt gtcctgttct tatttcattt tactatatat ctgaggtgta agtcctcggt
    34981 gggtacctgc taccggtgct cccaatagtg attcccaagc ctgactatcg tgaggtagcg
    35041 gattaaaacg gtctggggat agaccgtttt aagtctgacg ctggaaataa gaatcgtcag
    35101 aggaagggat agcgaaatcg tggctctacg aataggaacg tgataataag gcgtatatag
    35161 cggataaggg gcctcaaact ctaaagttca aaaaggtagt cgtagcctat atgcgtaaat
    35221 cacgagagca actgaatttg tctgttcgag gatggataaa ctatttctca ttgggaaata
    35281 tgaaaagtat agtcactagc atagatgagc gcttgcatac tcgcctacga gtgattatct
    35341 ggaagcaatg gaagaaaaaa tcgagatgat tatggggatt gcttaagtta ggggttccta
    35401 aatggatagc agataaggta tctggctg
//
LOCUS       DAVHBD010000019        35180 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000019 DAVHBD010000000
VERSION     DAVHBD010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.019"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            16..210
                     /locus_tag="VVK04_000995"
     CDS             16..210
                     /locus_tag="VVK04_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU3989663.1"
                     /translation="MEAEAIRRNCERGAIFSGKIKYHEDSQFKGDHYVECYAVLDNTV
                     IARDRITVPIDPLCGKDFIE"
     gene            455..1789
                     /gene="trmFO"
                     /locus_tag="VVK04_000996"
     CDS             455..1789
                     /gene="trmFO"
                     /locus_tag="VVK04_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU3989664.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            1873..2610
                     /locus_tag="VVK04_000997"
     CDS             1873..2610
                     /locus_tag="VVK04_000997"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU3989665.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2619..3176
                     /gene="frr"
                     /locus_tag="VVK04_000998"
     CDS             2619..3176
                     /gene="frr"
                     /locus_tag="VVK04_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU3989666.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3236..4090
                     /gene="cvfB"
                     /locus_tag="VVK04_000999"
     CDS             3236..4090
                     /gene="cvfB"
                     /locus_tag="VVK04_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU3989667.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPVLKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4099..4314
                     /locus_tag="VVK04_001000"
     CDS             4099..4314
                     /locus_tag="VVK04_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU3989668.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4400..5368
                     /locus_tag="VVK04_001001"
     CDS             4400..5368
                     /locus_tag="VVK04_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU3989669.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(5346..5525)
                     /locus_tag="VVK04_001002"
     CDS             complement(5346..5525)
                     /locus_tag="VVK04_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989670.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            5561..6061
                     /locus_tag="VVK04_001003"
     CDS             5561..6061
                     /locus_tag="VVK04_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989671.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6064..6324
                     /locus_tag="VVK04_001004"
                     /pseudo
     CDS             6064..6324
                     /locus_tag="VVK04_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6691..6984)
                     /locus_tag="VVK04_001005"
                     /pseudo
     CDS             complement(6691..6984)
                     /locus_tag="VVK04_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(6963..7802)
                     /gene="ald"
                     /locus_tag="VVK04_001006"
     CDS             complement(6963..7802)
                     /gene="ald"
                     /locus_tag="VVK04_001006"
                     /EC_number="1.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU3989672.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAVQIGAHFLTKQAGGSGVLLG
                     GVPGVPKGKVTIIGDGVVGTHAARIALGLGAQVTILDISAKRLSVLKEVFGSQIQTLI
                     SNSFNIEASVRDADVVIGAILIPGAKAPELVTDEMVKQMRPGSVSLTLLLTKVALSKQ
                     LTV"
     gene            7978..8547
                     /locus_tag="VVK04_001007"
     CDS             7978..8547
                     /locus_tag="VVK04_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989673.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKVAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8615..9265
                     /locus_tag="VVK04_001008"
     CDS             8615..9265
                     /locus_tag="VVK04_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEU3989674.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGFGTASSISKEKKVNINKA
                     SLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKTVSGIGAKTIEKLKDYVTVD"
     gene            9249..11489
                     /locus_tag="VVK04_001009"
     CDS             9249..11489
                     /locus_tag="VVK04_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU3989675.1"
                     /translation="MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCL
                     FFQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKTSQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11668..11856
                     /locus_tag="VVK04_001010"
     CDS             11668..11856
                     /locus_tag="VVK04_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989676.1"
                     /translation="MTATKSYKYDWNTVLEYSINYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            11888..12475
                     /locus_tag="VVK04_001011"
     CDS             11888..12475
                     /locus_tag="VVK04_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989677.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12479..13663
                     /locus_tag="VVK04_001012"
     CDS             12479..13663
                     /locus_tag="VVK04_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989678.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLICLIILLLVGILFIERWGSSRKKEVFN
                     RS"
     misc_feature    13830..13961
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            13977..14507
                     /gene="infC"
                     /locus_tag="VVK04_001013"
     CDS             13977..14507
                     /gene="infC"
                     /locus_tag="VVK04_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU3989679.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14540..14740
                     /gene="rpmI"
                     /locus_tag="VVK04_001014"
     CDS             14540..14740
                     /gene="rpmI"
                     /locus_tag="VVK04_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU3989680.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHCFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14792..15151
                     /gene="rplT"
                     /locus_tag="VVK04_001015"
     CDS             14792..15151
                     /gene="rplT"
                     /locus_tag="VVK04_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU3989681.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15209..15589
                     /locus_tag="VVK04_001016"
     CDS             15209..15589
                     /locus_tag="VVK04_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU3989682.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            15839..16639
                     /locus_tag="VVK04_001017"
     CDS             15839..16639
                     /locus_tag="VVK04_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU3989683.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLFEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            16650..17588
                     /locus_tag="VVK04_001018"
     CDS             16650..17588
                     /locus_tag="VVK04_001018"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU3989684.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17630..19663
                     /locus_tag="VVK04_001019"
     CDS             17630..19663
                     /locus_tag="VVK04_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU3989685.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKYGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLESD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSTDGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(19724..21379)
                     /gene="pavA"
                     /locus_tag="VVK04_001020"
     CDS             complement(19724..21379)
                     /gene="pavA"
                     /locus_tag="VVK04_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU3989686.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21484..21981
                     /gene="ybeY"
                     /locus_tag="VVK04_001021"
     CDS             21484..21981
                     /gene="ybeY"
                     /locus_tag="VVK04_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU3989687.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEITFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            21962..22357
                     /locus_tag="VVK04_001022"
     CDS             21962..22357
                     /locus_tag="VVK04_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU3989688.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22374..23273
                     /gene="era"
                     /locus_tag="VVK04_001023"
     CDS             22374..23273
                     /gene="era"
                     /locus_tag="VVK04_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU3989689.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23322..24146
                     /gene="mutM"
                     /locus_tag="VVK04_001024"
     CDS             23322..24146
                     /gene="mutM"
                     /locus_tag="VVK04_001024"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU3989690.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24146..24751
                     /locus_tag="VVK04_001025"
     CDS             24146..24751
                     /locus_tag="VVK04_001025"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU3989691.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24738..25937
                     /locus_tag="VVK04_001026"
     CDS             24738..25937
                     /locus_tag="VVK04_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEU3989692.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            25937..26086
                     /gene="rpmG"
                     /locus_tag="VVK04_001027"
     CDS             25937..26086
                     /gene="rpmG"
                     /locus_tag="VVK04_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU3989693.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26126..26359
                     /gene="secG"
                     /locus_tag="VVK04_001028"
     CDS             26126..26359
                     /gene="secG"
                     /locus_tag="VVK04_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU3989694.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26461..28815
                     /gene="rnr"
                     /locus_tag="VVK04_001029"
     CDS             26461..28815
                     /gene="rnr"
                     /locus_tag="VVK04_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU3989695.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVLSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28778..29245
                     /gene="smpB"
                     /locus_tag="VVK04_001030"
     CDS             28778..29245
                     /gene="smpB"
                     /locus_tag="VVK04_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU3989696.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29261..30121
                     /gene="tehB"
                     /locus_tag="VVK04_001031"
     CDS             29261..30121
                     /gene="tehB"
                     /locus_tag="VVK04_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU3989697.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30194..31147
                     /gene="coiA"
                     /locus_tag="VVK04_001032"
     CDS             30194..31147
                     /gene="coiA"
                     /locus_tag="VVK04_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU3989698.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31166..32968
                     /gene="pepF"
                     /locus_tag="VVK04_001033"
     CDS             31166..32968
                     /gene="pepF"
                     /locus_tag="VVK04_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU3989699.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            32970..33683
                     /locus_tag="VVK04_001034"
     CDS             32970..33683
                     /locus_tag="VVK04_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU3989700.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            33750..34691
                     /gene="prsA"
                     /locus_tag="VVK04_001035"
     CDS             33750..34691
                     /gene="prsA"
                     /locus_tag="VVK04_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU3989701.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(34808..35149)
                     /locus_tag="VVK04_001036"
                     /pseudo
     CDS             complement(34808..35149)
                     /locus_tag="VVK04_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        10597 a         6535 c         7925 g        10123 t
ORIGIN      
        1 tggaaagtaa gaaatattga agctgaggct attagaagaa attgtgagcg tggtgctatt
       61 ttttcaggta aaataaaata tcacgaagat tcacagttta aaggagatca ctatgttgaa
      121 tgttatgctg ttttagataa tacggttata gcaagagata gaataacagt ccctatcgat
      181 ccgttatgtg gaaaagattt tatagagtag catataattg attcttaact ggaatactca
      241 ctatctcttt acatcaagaa aatgactaaa cagggaagtt tgccttcttc cctttttttg
      301 ttatactagt agaagaaaaa atagaaagat ttgtgggagt gaaaaagtcc tgtggacttt
      361 ttcagcctga gccaagaaac tcgaaagctc gtaagtctga ttggcttttt caatgtgaat
      421 cttaacttca tactcccaaa gaggtattag tgtcgtgtct caatcttata tcaatgttat
      481 cggtgctggt ttggcaggtt ctgaagcagc ctaccaaatc gcagagcgtg gtattccagt
      541 taaactttat gaaatgcgtg gtgtcaagtc aacacctcag cacaaaacag acaattttgc
      601 tgagttggtt tgttccaatt ccttgcgtgg agatgctttg acaaatgctg ttggcctcct
      661 taaggaagaa atgcgtcgct tgggttctgt gattttggaa tctgctgagg ctacacgtgt
      721 tcctgcaggt ggtgcccttg cagtggaccg tgatggtttc tctcaaatgg tgaccgaaaa
      781 agttgccaac caccccttga ttgaagtggt tcgtgatgaa attacagaat tgccgacaga
      841 tgttattacg gttatcgcta ctggtccttt gacaagtgat gccttggctg aaaagattca
      901 tgcccttaat gacggtgatg gtttttattt ctacgatgcg gcagcgccta ttatcgatgt
      961 caacactatc gatatgagca aggtctacct caaatcacgt tatgataagg gagaagcggc
     1021 ctacctcaat gcccctatga ccaagcaaga atttatggat ttccatgaag ctttggtcaa
     1081 tgcagaagaa gcaccgctta attcttttga aaaagaaaag tactttgaag gatgtatgcc
     1141 tatcgaagtc atggccaaac gtggcattaa aaccatgctt tatggtccta tgaaaccagt
     1201 tggtcttgag tatccggacg actacacagg acctcgtgat ggagaattta aaacacctta
     1261 tgcggttgtc cagctccgtc aggataatgc agctggtagc ctatacaata ttgttggttt
     1321 ccagacccac ctcaaatggg gagaacaaaa gcgtgtcttc caaatgattc cgggtcttga
     1381 aaatgcggag tttgtccgtt atggtgtcat gcatcgcaat tcttacatgg attcaccaaa
     1441 tcttcttgag cagacttacc gttccaagaa acaaccaaat ctcttctttg ctggtcagat
     1501 gacgggggtg gaaggctatg ttgagtcggc ggcttcgggc ttagttgcgg gaattaacgc
     1561 agctcgtctc ttcaaggaag aaagcgaggt tattttcccc gagacgacag cgattggaag
     1621 cttagctcat tacattaccc atgccgacag caaacatttc caaccaatga atgtcaattt
     1681 tgggatcatc aaggagttgg aaggcgagcg tatccgtgat aagaaggctc gttatgaaaa
     1741 aattgcagag cgtgcccttg ccgacttaga ggaatttttg actgtctaat ttttttgaaa
     1801 gaattgctca tgatactata aaaatcttag aaattgtgat aaaataggta ggatgaaaga
     1861 aggagagtga aaatggcgaa tcccaagtat aaacgtattt taatcaagtt atcaggtgaa
     1921 gcccttgccg gtgaacgtgg cgtagggatt gatatccaaa cagttcaaac aatcgcaaaa
     1981 gagattcaag aagttcatag cttaggtatc gaaattgccc ttgttattgg tggaggaaat
     2041 ctttggcgtg gagaacctgc agcagaagca ggtatggacc gtgttcaggc agattacact
     2101 ggaatgcttg ggactgttat gaatgctctt gtgatggcag attcattgca acaagttggg
     2161 gttgatacgc gtgtacaaac agctattgct atgcaacaag tggcagagcc ttatgtccgt
     2221 ggacgtgccc ttcgtcacct tgaaaaaggc cgtatcgtta tctttggtgc tggaattggt
     2281 tcaccatact tctcgacaga tacaacagcg gcccttcgtg cagctgaaat cgaagcagat
     2341 gccatcctca tggctaaaaa tggcgtcgat ggtgtgtaca atgccgatcc taagaaggac
     2401 aagacagccg ttaagtttga agaattgacc caccgtgatg ttatcaacaa aggtcttcgt
     2461 atcatggact caacagcctc aaccctctca atggacaacg acattgactt ggttgtcttc
     2521 aacatgaacc aatcaggcaa catcaaacgt gtcgtatttg gtgaaaatat cggaacaaca
     2581 gtttcaaata atatcgaaga aaaggaataa gaaagaatat ggctaacgta attattgaaa
     2641 aagctaaaga gagaatgacc caatctcacc aatcacttgc tcgtgaattt ggtggtatcc
     2701 gtgctggtcg tgccaatgca agcttgcttg accgtgtaca tgtagaatac tatggagtcg
     2761 aaactcctct taaccaaatc gcttcaatta cgattccaga agcgcgtgtt ttgttggtaa
     2821 caccatttga caagtcttca ttgaaagaca tcgaacgtgc cttgaacgct tctgatcttg
     2881 gtatcacacc ggctaatgac ggttctgtga ttcgcttggt tatcccagct cttacagaag
     2941 aaactcgtcg tgaccttgct aaagaagtga agaaggtcgg cgaaaatgct aaagtggctg
     3001 tccgcaatat ccgtcgcgat gctatggacg aagctaagaa acaagaaaaa gcaaaagaaa
     3061 tcactgaaga cgaattgaag actcttgaaa aagatattca aaaagtaaca gacgatgctg
     3121 ttaaacacat cgacgacatg actgctaaca aagagaaaga acttttggaa gtctaaaaat
     3181 aaacagaaaa actcagttgg cattgctggc tgagttttat tcgaaagaag gaaatatgaa
     3241 tacaaatctt gcaagtttta tcgttggact gatcatcgat gaaaatgacc gtttttactt
     3301 tgtgcaaaag gatggtcaaa cctatgctct tgctaaggaa gagggccaac atacagtagg
     3361 ggatacggtc aaaggttttg catacacgga tatgaagcaa aaactccgcc tgacaacctt
     3421 agaagtgact gccactcagg accaatttgg ttggggacgt gtcacagagg ttcgtaagga
     3481 cttgggtgtc tttgtggata caggccttcc tgacaaggaa atcgttgtgt cactcgatat
     3541 tctccctgtg ctcaaggaac tctggcctaa gaagggcgac caactctaca tccgtcttga
     3601 agtggataag aaagaccgta tctggggcct cttggcttat caagaagact tccaacgtct
     3661 cgctcgtcct gcctacaaca acatgcagaa ccaaaactgg ccagccattg tttaccgtct
     3721 caagctgtca ggaacttttg tttacctacc agaaaataat atgcttggtt ttattcatcc
     3781 tagcgagcgt tacgcagagc cacgtttggg gcaagtatta gatgcgcgcg ttattggttt
     3841 ccgtgaagtg gaccgcactt tgaacctctc cctcaaacca cgctcctttg aaatgttgga
     3901 aaacgatgct cagatgattt tgacttattt ggaaagcaat ggcggtttca tgaccttaaa
     3961 tgacaagtca tctccagacg acatcaaggc aacctttggc atttctaaag gtcagttcaa
     4021 gaaagcttta ggtggtctta tgaaggctgg taaaatcaag caggaccagt ttggtacaga
     4081 gttgatttag ggaggcttat gagaaaatca ttttacactt ggctcatgac cgagcgcaat
     4141 cctaaaagta acagtcccaa agcaattttg gcagacctcg cttttgaaga ggcagctttt
     4201 ccaaaacata cagatgattt tgatgaggtc agtcgctttt tggaggagca tgccagtttc
     4261 tcttttaacc taggagattt tgacagcatt tggcaggaat atctagaaca ctagcattta
     4321 ttcattgggt ttgggctagt aatttctcca tccctctgct ataataaaaa gaaataaaag
     4381 gattagagag gttctttatt tgaaggaaca ttcaatagac attcaactga gtcatccaga
     4441 tgacctgttt catctttttg gttccaatga gcgccatctt cgtttgatgg aagaagagct
     4501 ggatgtggtg attcatgctc gtacggagat tgtccaggtt ttgggagaag agtctgcttg
     4561 tgaggaagcc cgtcaggtta ttcaagctct catggtcttg gtgaaccgtg ggatgaccgt
     4621 tggtacgcca gatgtggtga ctgcaattag catggtcaaa aacgatgaaa ttgataagtt
     4681 tgtcgccctt tacgaagaag aaattatcaa agataatact gggaaaccga tccgcgtcaa
     4741 aaccttaggt caaaaacttt atgtggacag tgtcaaacag catgatgtga cctttggaat
     4801 tgggcctgca gggacgggga agacctttct tgcagttact ttggcagtga ctgcccttaa
     4861 acgtgggcaa gtcaagcgga ttatcttgac acgtccagcg gtggaagcag gagagagtct
     4921 aggttttctt ccgggtgatc ttaaggagaa ggtagatcct taccttagac ctgtttatga
     4981 tgccttgtat cagattctgg ggaaagacca aacaactcga ctcatggagc gtgaaattat
     5041 cgagattgcg ccccttgcct atatgcgtgg acggaccttg gatgatgcct ttgtcattct
     5101 cgatgaggcg caaaatacga ccatcatgca gatgaagatg ttcttgactc gtttaggttt
     5161 tcattctaag atgattgtca atggagatat tagtcagatt gacctgccac gtaatgtcaa
     5221 gtccggtttg attgatgctc aagagaaact caagaacatc catcagattg actttgttca
     5281 tttttcagcc aaggatgtgg ttcgccatcc tgttgtcgct cagattatcc gagcctatga
     5341 atattctact gaagttgcac acgactgatt ttgaggaagt tcgcctgcaa aagaatatac
     5401 ttttgagaga ggaaaatcca gttgtatagg ctaaaggttt tatccaaagg tttgagacaa
     5461 cgattaggca cgatggaaag aacttttatg tggctgatga cgatcagtgc atcttcctgt
     5521 gtcataatca cagggcacaa gaaagtagga atttgaaaag atgattgacc aactatctaa
     5581 gtattacagt tgtaggatac taactgaaaa ggatattcca agtattttat ctttatatga
     5641 aagtaatcct ctgtattttc agcattgtcc accagagcca aattttgcaa ctgtaaaaga
     5701 ggacatgctt tgtctacctg aaggtaaagc taaggctgat aagttttttg ttggattttg
     5761 gaatggatct gaccttgtgg ctgttatgga ttttgtctat gcatatcctg atgaggagac
     5821 tgtttttatt ggtttgttta tggttgatca agcctatcag aggaaaggga ttggtagtca
     5881 tattgtgaca gaagcactag cttattttgc taagaacttt cgaaaggcac gtttggctta
     5941 tgttaaggga aatccgcaat ctcagcattt ttgggaaaag cagggcttta aatcaattgg
     6001 atgcgaggtt aagcaagaac tctatacggt tgttatcgct gaacagagcc tagaagatta
     6061 gaaatggcat caagtaagaa ctatttggaa tttgttttgg aacaattatc aggattagat
     6121 gatgtgactt accgttccat gatgggggag tatattcttt acttccgcgg caagattatt
     6181 ggcggcattt atgacgatcg ctttttagtt aaacccgtgc aagcagtctt agataagatt
     6241 gaccaatctt cttttgagtt tccatacaaa ggtgccaaag aaatgatttg agtggaagaa
     6301 cttgataata agatgtttct ataagacctg attttagcta tgtataacca actgccaacg
     6361 cccaaaccta aaaagaaaaa gcaagggtga acgaagtaaa aaagaagtct gctaaggccc
     6421 tgtctttgca cgggtaaaat tttatatata aaaagaagct gggactaaag agctcagctt
     6481 cctttggttt atataattgt cattacaaga cgaagtggtt gggcgaaact ctgttgactt
     6541 tattcaattt agagtttctt atgcacaatt gagtctggaa cgaaagtctc cagttgcaaa
     6601 gtatacagta caataaacca acgatgtaat agctgatgac acaaagcaca gtgggtagga
     6661 cttgcgaagt cacccttttc ttttcaaaat ttatactaaa tcattgatat cagtgtagtc
     6721 acgattaagt ccttgagcaa ctggtaggct agtcaagtaa ccttgataag tggtcacacc
     6781 ttgacgcaag ccttcatctt cagagattgc ttatgcgaat cctttgccag ccaaagcttc
     6841 gatataagga agagtgacat tggttagggc gatggttgaa gtgcgggcaa ccgcaccagg
     6901 gatattggca acggcatagt ggagaacacc gtgtttttca tagacgggtt catcgtgcgt
     6961 tgtcacacgg tcagctgttt cgataaggcc accttggtca acagcaacgt caacgataca
     7021 gagcctggac gcatttgttt gaccatctca tctgtcacca attccggtgc ttttgcacca
     7081 gggatgagaa tggctccaat caccacatca gcatctctca cacttgcttc aatgttgaat
     7141 gaattagata taagagtttg aatttgactt ccaaagactt cttttagaac tgagagacgc
     7201 ttggcactaa tatctaaaat agtcacttga gcaccaagac caagggcgat gcgggcagca
     7261 tgtgtaccga cgacaccatc accgatgata gttacttttc cttttggaac acctggtaca
     7321 ccaccaagta gaacaccaga gccaccagct tgcttagtaa ggaagtgagc tccgatttga
     7381 acagccatac gacctgcaac ctcactcata ggaacgagga gcggtagttg tccttgattg
     7441 tcacgaacag tttcataggc aattcctgtt gtttttgctg ctaacatagc atctgctaat
     7501 tctggagcag cggccatgtg caagtaggtg aagagaagaa gatcgtcgcg caagtaaccg
     7561 tattcagaac ttaaaggttc ttttactttc acaaccaact ctgctgccca agcttcacca
     7621 gcagtagcga caatctcagc tccttgcttt tgatagtcag catcagtaaa gccagaaccg
     7681 agaccagcat ttgtttcgat aaggacacga tgaccacgac taactaagct atgaacacct
     7741 gcaggtgtga gggcgacacg gttttcgtta tttttaattt cttttgggat tccgattaac
     7801 attgagataa cctacctttc aattgacggt cttgttttgg ttgtcacatt ccagttcata
     7861 aatcaaaaat gtgacggttt cattgtatat gaaaccgctt caaaaatcaa gaaaaacttg
     7921 tcatccaaat tttttatgct agactagtga aaatcaagct ctaatggagg gaaaagtatg
     7981 gaatcaattt ttgtaaaact tgcccagtat ccgtctatag aaacggagcg tttattgctt
     8041 agacctgtaa ctttggatga tgcggaagca atgtttgact atgcctcgga caagggtaat
     8101 acacgttaca cttttccaac caatcaaagc ttggaagaaa ccaagaataa cattgctcag
     8161 ttctacttgg ctaatccctt gggacgttgg gggattgaat taaaagataa cggcaagttt
     8221 atcggaacta ttgacttaca caagattgat cctgttctta agaaggtagc tattggctac
     8281 attatcaata aaaagtattg gaatcaagga ttaacgacag aagccaatcg tgctgtgatt
     8341 gagctagctt ttgagaagat agggatgaat aagttgactg cccttcacga taaggacaat
     8401 cctgcgtcag gaaaggtcat ggagaaatca ggcatgcgtt tttcccatgc agaaccatat
     8461 gcttgtatgg accagcatga aaaaggccga atcgtgacaa gagttcatta tgtcttgacc
     8521 aaggaagact attttgcaaa taaataagca gttgaaaaga aatttttcga ctgttttttc
     8581 ttcctcttac gaataatcta agagaggaga aaatatggaa gcaattatcg agaaaatcaa
     8641 agagtataaa atcatcgtca tctgtactgg tctgggcttg cttgtaggag gatttttcct
     8701 gctaaaacca gctccacaaa cacctgtcaa agagacgaat ttgcaggctg aagtcgcagc
     8761 tgtttccaag gatttggtat ccgaaaagga agtgaacaag gaagaaaagg aagaacccct
     8821 tgaacaagat ctaatcacag tagatgtcaa aggtgctgtc aaatcgccag ggatttatga
     8881 cttgcctgta ggtagtcgag tcaatgatgc tgttcagaag gctggtggct tgacagagca
     8941 agcagacagc aagtcgctca atctagctca gaaagttagt gatgaggctc tggtttacgt
     9001 tcctactaag ggagaagaag cagttagcca acagactggt tttgggacag cttcttcaat
     9061 aagcaaggaa aagaaggtca atatcaataa ggccagtctg gaagaactca agcaggtcaa
     9121 aggactggga ggaaaacgtg ctcaggatat tatcgaccat cgtgaaacaa atggcaagtt
     9181 caagtcagta gacgaactca agacagtctc tggcattggt gctaagacca tagaaaagct
     9241 aaaagactat gttacagtgg attaagaaca tccccattcc cctaatttac ctgagttttt
     9301 tgttactttg gttttattac gctattttct cagcatccta tcttgctttg ttgggctttg
     9361 tttttctgct agtctgtctc tttttccaat ttccttggaa atctgctggt aaagttctaa
     9421 taatttgcgg aatctttgga ttttggtttg tttttcaaaa ttggcaacag agtcaagcga
     9481 gtcaaaatct ggcggattct gttgaaaggg tacggatttt acctgatact attaaggtta
     9541 atggtgatag tctatccttt cgtggcaagt ctaacggtcg tgctttccaa gtctattata
     9601 aactccagtc cgaggaggag aaagaagcct ttcaagcttt aaccgacctg catgagatag
     9661 gactagaagg gaagctttcg gagccagaag ggcagagaaa ttttggtggc tttaattacc
     9721 aagcctatct gaagactcag ggaatttacc agactctcaa tatcaaaaca atccagtcac
     9781 ttcaaaagat tggcagttgg gatataggag aaaacttgtc cagtttacgt cgaaaggctg
     9841 tggtttggat taagacgcac tttccagacc ctatgcgcaa ttacatgaca ggactcttgc
     9901 tgggacatct ggacaccgac tttgaggaga tgaatgagct ttattccagt ctaggaatta
     9961 tccacctctt tgccctatct ggtatgcagg taggtttttt catgaatgga tttaagaaac
    10021 ttctcttgcg attgggcttg acccaagaaa agttgaaatg gctgacttat cccttttccc
    10081 ttatctatgc gggactaact ggattttcag catcggttat tcgcagtctc ttgcaaaagc
    10141 tactggctca acatggggtt aagggcttgg ataattttgc cttgacggtg cttgtcctct
    10201 ttattgtcat gccaaacttt ttcttgacag caggaggagt cttgtcctgc gcttatgctt
    10261 ttatcctgac catgaccagc aaagaagggg aggggctcaa ggctgttact agtgaaagtc
    10321 tagtcatctc cttgggcata ttgcccattc tatccttcta ttttgcggaa tttcaacctt
    10381 ggtctatcct tttgaccttt gtcttttcct ttctatttga cttgaccttc ttaccgctct
    10441 tgtctatttt atttgtcctt tcctttctct atccagtcat tcagctgaac tttatctttg
    10501 aatggttgga gggcattatt cgcttggtgt cacaggtgac aagtagacct ctggtctttg
    10561 gacaacccaa tgcatggttt ttaatcctat tgttaatttc cttggctttg gtttatgatt
    10621 tgagaaaaaa cattaaaaag ctaacggtat tgtgcttatt gattacaggg ctctttctcc
    10681 tgaccaagca tccactggaa aatgaaatca ccatgctgga tgtggggcaa ggagaaagta
    10741 ttttcctacg ggatgtaact gggaaaacca ttctcataga tgtaggtggt aaggcagaat
    10801 cttataagaa aatcgaaaaa tggcaagaaa agatgacgac cagcaatgcc cagcgaacct
    10861 tgattcccta tctcaaaagt cgaggagtag ctaagattga ccagctaatt ttgactaaca
    10921 cggacaagga gcatgttgga gatttgtcag aggtgaccaa ggctttccat gtaggggaga
    10981 ttctagtatc aaaagacagt ctgaaacaga aggaatttgt ggcagaacta caggcgactc
    11041 aaacaaaggt gcgtagtatg acagtagggg agaacttgcc catttttgga agtcagttag
    11101 aagttctatc tccaaggaaa atgggagatg gaggacacga tgatacccta gttctgtatg
    11161 ggaaattctt ggataagcaa tttctcttca cgggaaattt ggaggagaaa ggagagaagg
    11221 acttgctgaa gcactatcca gacttgaaag taaatgtttt gaaaactagc caacatggca
    11281 ataaaaaatc atcaagtcca gcctttctag aaaaactcaa accagagctt actcttatct
    11341 cagttggaaa gagcaatcga atgaaactcc cccatcagga aacattgaca cgactggaag
    11401 gtatcaatag caaagtttat cgaactgacc agcaaggagc tatacgtttt aaggggttgg
    11461 atagttggaa aatcgaaagt gttcgatagg aaggataaat gttgtagatt agtgaaataa
    11521 actaaaaatt tgttgcataa taatgataaa aatggtataa tgaaaacgta ttcaatattg
    11581 aggatataaa atcattaaaa atcagcaaaa gttgttttat tagttagttt ataatctatt
    11641 ggtcttcttc agtccagtgt atctgctgtg acagccacta aaagttacaa gtatgattgg
    11701 aatacggttt tggaatatag tatcaactat cacgaccatc agtatgcttg gattccggaa
    11761 tggtctcgtt attacagcta ttctgagtat aaagttggcg gaggctggaa ctacgctcgt
    11821 tatgaggtca taaactacta tactggaggt tattaatcct taaagagtga gaaaaggagg
    11881 gctggatatg ttaaatctta ctcatgttac cttaaaaacg cgacaagtca tcttgcaaga
    11941 tgcggatttt acctttaaaa agggtaggat ttatggcctt cttgctatca atggctcggg
    12001 aaagacgaca ctattccgag ctatgagcaa gttgcttccc cttagtagtg gacacatcgc
    12061 agttcctcct tctttgtttt attatgagag cgttgaatgg ctggatggaa acttaagtgg
    12121 gatggactac cttcgtctca taaaaaacat ctggaagtca gacctaaact tgagagatga
    12181 aatcgcctac tgggaaatgg ctgactatat cagtcttccc atccgcaagt attccttagg
    12241 catgaagcaa cgcttggtga ttgctatgta ttttctcagt caggccaaat gctggctcat
    12301 ggatgagatt acaaatggct tagacgagta ttatcgacag aagttttttg ataggctagc
    12361 acaaatcgat agacaagaac agctggttct tttaagttcc cactataagg aagagttggt
    12421 tgatatctgc gatagagtag taaccattca tcaggggcag atagaagagg tttagtttat
    12481 gaaagatgtt agtctatttt tattgaaaaa agttttcaaa agtcgtttaa actggattat
    12541 cttactttta tttgcatctg tactcggtgt taccttttat ttaaatagtc agactgcaaa
    12601 ctcacacagc ttggagagca ggttggaaag tcgcattgca gccaacgaga gggctatcaa
    12661 tgaaaatgaa gagaaactct cccaaatgtc tgataccagc tcggaggaat accagtttgc
    12721 taaaaataat ttagacgtgc aaaaaaatct tttgacgcga aagacagaaa ttctaacttt
    12781 actaaaagaa gggcgctgga aagaagccta ctatctgcag tggcaagatg aagagaagaa
    12841 ttatgaattt gtatcaaatg acccgactgc tagctctggc ttaaaaatgg gggttgaccg
    12901 cgaacggaag atttaccaag ccctgtatcc cttgaacata aaagcacata ctttggagtt
    12961 tccgacccac gggattgatc agattgtctg gattttagag gttatcatcc caagcttgtt
    13021 tgtggttgcg attattttta tgctaacaca actatttgca gaaagatatc aaaatcatct
    13081 ggacacagct cacttatatc ctgtttcaaa agtgacattt gcaatatcct ctcttggagt
    13141 tggagtggga tatgtaactg tgctgtttat cggaatctgt ggcttttctt ttctagtggg
    13201 aagtctgata agtggttttg gacagttaga ttatccctac ccaatttata gcttagtgaa
    13261 tcaagaagta actattggga aaatacaaga tgtattattt cctggcttgc tcttagcttt
    13321 cttagccttt atcgtcattg tggaagttgt gtacttgatt gcttactttt tcaagcaaaa
    13381 aatgcctgtc ctctttcttt cactcattgg gattgttggc ttattgtttg gcatccaaac
    13441 cattcagcct cttcaaaaga ttgcacatct gattcccttt acttacttgc gttcagtgga
    13501 gattttatct ggaagattac ctaagcagat tgataatgtc gatctaaatt ggagcatggg
    13561 aatggtctta cttatttgct tgattatcct tttgttagtg gggattctat ttatcgaaag
    13621 atggggaagt tcacgtaaaa aggaagtttt taataggtct tagtattcct atagggaagg
    13681 tgaggaaaaa actaacagag tgagggaacc aactaggttc tctctttttg attcgaaaac
    13741 caaaccaaaa tacaaacaca aacacaaact tttcaaaaaa taacttttta tcttgacaag
    13801 agctagaaaa cttggtatca tataaaagtt gagaaaagca gaagtgagag cttctcgcct
    13861 tgtgacatta agttgcctgg ccctacggat gaaaagtttc gaagaaacgc tatcataacg
    13921 tgcgggcttg tatatttacg agtccgctat tgtttttctc taataaaaca aaagaggtga
    13981 aaaccatagc aaagcaagac ttattcatca atgatgagat tcgtgtacgt gaagttcgct
    14041 tgattggtct tgaaggagaa cagctaggca tcaagccact cagtgaagcg caagctttgg
    14101 ctgataacgc taatgttgac ctagtattga ttcaacccca agccaaaccg cctgttgcaa
    14161 aaattatgga ctacggtaag ttcaaatttg agtaccagaa gaagcaaaaa gaacaacgta
    14221 aaaaacaaag cgttgttact gtgaaagaag ttcgtctaag tccaacaatt gacaagggtg
    14281 actttgatac aaaacttcgc aatgcacgta agttccttga aaaaggaaat aaagttaagg
    14341 tatctattcg ctttaagggt cgtatgatta cccataaaga gattggtgca aaagttttag
    14401 ccgagtttgc tgaagcaact caagatattg ccatcatcga acaacgtgct aaaatggatg
    14461 gacgtcaaat gttcatgcaa ttggcgccag cgactgacaa aaaataattg tcagaaagtt
    14521 aaataaagga gaaaaaatca tgccaaaaca aaaaacacac cgcgcatcag ctaaacgttt
    14581 caaacgtaca ggttctggtg gacttaaacg tttccgtgct tacacttctc actgtttcca
    14641 cggaaaaact aagaaacaac gtcgtcatct tcgtaaagca tctatggtgc attcaggaga
    14701 ttacaaacgt atcaaagcaa tgcttactcg cttgaaataa tagcttgact gtaagtaaac
    14761 aattctagga aatatttgga ggaaataaaa catggcacgt gttaaaggtg gcgttgtatc
    14821 acgcaaacgt cgtaaacgta ttcttaaatt agcaaaaggt tactatggag ctaaacacat
    14881 cttgttccgt actgcaaaag aacaagtaat gaactcttac tactatgcat accgtgaccg
    14941 tcgtcagaaa aaacgtgact tccgcaaatt gtggattact cgtatcaatg cggcagctcg
    15001 tatgaacgga ctttcatact cacaattgat gcatggtttg aaattggctg agattgaagt
    15061 taaccgtaaa atgcttgctg acttggctgt taacgatgca gtagctttca cagctcttgc
    15121 agatgcagct aaagcaaaac ttggtaaata acaactgatg agactggaac aggattgtcc
    15181 agtcttttta aaaataaagg agaaagatat ggcttcaaaa atgctacaca cttgcttacg
    15241 agtagaaaat cttgaaaaat caatcgcatt ttatcaagat gcttttggtt ttaaagaatt
    15301 gcgtcgcaga gattttccag accatgcctt cacgattgtc tatctaggtc ttgagggtga
    15361 tgactatgag ttggagttga cttataacta cgatcacggt ccgtatgtgg ttggtgatgg
    15421 gtttgcccat atcgccctca gtacacctga tcttgaggca cttcatcaag aacacagtgc
    15481 aaaaggctat gaagtgactg agccaaatgg tctaccagga actacaccaa actattactt
    15541 tgtcaaagac cctgatggat ataaggtcga agtcattcgt gaaaaataat ttcgtgcaag
    15601 ttaagtagaa tattcgtttt ctacttgact ttttttagct gaaagagtat actaataaaa
    15661 attcaacctt taaggggagt ccagagagac tcacaaggtg tcagataaaa gaatagtgca
    15721 attttctaga ggagactttt tgagtgtgct ctcttgtgtt gtacgatttt aactgaggcc
    15781 ttgcactagc aaggtctttt ctttatctgg tccccttaaa atttaaggag gaaaagttat
    15841 gaatcccaca tgtaagaagc gtttgggtgt cattcggttg gaaaccatga aggtggttgc
    15901 acaagaggaa atcgcgccag caatctttga attagtccta gaaggagaaa tggttgaagc
    15961 catgcgagca ggccaatttc ttcatctgcg tgtaccagac gatgcccatc tcttacgtcg
    16021 tcctatttca atttcgtcta ttgacaaggc aaacaagcag tgtcacctca tttatcggat
    16081 tgagggagct gggactgcaa ttttttcaac cttaagtcag ggagacactc ttgatgtgat
    16141 ggggcctcag ggaaatggtt ttgacttgtc tgaccttgat gagcagaatc aggttctcct
    16201 tgttggtggt gggattggtg ttccaccctt gtttgaggtg gccaaggaat tgcatgaacg
    16261 tggagtgaaa gtagtgacag tcctcggttt tgctaataag gatgctgtta ttttgaaaac
    16321 ggaattggct cagtatggtc aggtctttgt aacgacagat gatggttctt atggcatcaa
    16381 gggaaatgtt tccgttgtta tcaatgattt agatagtcag tttgatgctg tttactcgtg
    16441 tggggctcca ggaatgatga agtatatcaa tcaaaccttt gatgatcacc caagagccta
    16501 tttatctctg gaatctcgta tggcttgtgg gatgggagct tgctatgcct gtgttctaaa
    16561 agtaccagaa agcgagacgg tcagccaacg cgtctgtgaa gatggtcctg ttttccgcac
    16621 aggaacagtt gtattataag gagaaaatta tgactacaaa tcgattacaa gtgtctctac
    16681 ctggtttgga tttgaaaaat ccgattattc cagcatcagg ctgttttggc tttggacaag
    16741 agtatgccaa gtactatgat ttagaccttt taggttctat tatgatcaag gcgacaaccc
    16801 ttgaaccacg ttttgggaat ccaactccaa gagtggcaga gacgcctgct ggtatgctca
    16861 atgcaattgg cttgcaaaat cctggtttag aggttgtttt ggctgaaaag ctaccttggc
    16921 tggaaagaga atatccaaat cttcctatta ttgccaatgt agctggtttt tcaaaacaag
    16981 agtatgcagc tgtttctcat gggatttcca aggcaactaa tgtaaaagct atcgagctca
    17041 atatttcttg tcccaatgtt gaccactgta atcatggact tttgattggt caagatccag
    17101 atttggctta tgatgtggtg aaagcagctg tggaagcctc agaagtgcca gtttatgtca
    17161 aattaacccc gagtgtgacc gatatcgtta ctgtcgcaaa agctgcagaa gatgcgggag
    17221 caagtggctt gaccatgatc aatactctgg ttggaatgcg ctttgacctc aaaaccagaa
    17281 aaccaatctt ggccaatgga acaggtggaa tgtcaggtcc agcagtcttt ccagtagccc
    17341 tcaaactcat ccgccaagta gcccaaacaa cagacctgcc tatcattgga atggggggag
    17401 tggattcggc tgaagctgcc ctagaaatgt atctggctgg ggcatctgct atcggagttg
    17461 gaacagctaa ctttaccaat ccttatgcct gtcctgacat catcgaaaat ttaccaaaag
    17521 tcatggataa atacggtatt agcagtctgg aagaactccg tcaggaagta aaagagtctc
    17581 tgaggtaaac tgcaatcaat ctgttcttga ttttttatta gtttgtaata tgaatttagg
    17641 agaattttgg tacaataaaa taaataagaa cagaggaaga aggttaatga agaaagtaag
    17701 atttattttt ttagctctgc tatttttctt agctagtcca gagggtgcaa tggctagtga
    17761 tggtacttgg caaggaaaac agtatctgaa agaagatggc agtcaagcag cgaatgagtg
    17821 ggtttttgat actcattatc aatcttggtt ctatataaaa gcagatgcta actatgctga
    17881 aaatgaatgg ctaaagcaag gtgacgacta tttttacctc aaatatggtg gctatatggc
    17941 caaatcagaa tgggtagaag acaagggagc cttttattat cttgaccaag atggaaagat
    18001 gaaacgaaat gcttgggtag gaacttccta tgttggtgca acaggtgcca aagtaataga
    18061 agactgggtc tatgattctc aatacgatgc ttggttttat atcaaagcag atggacagca
    18121 cgcagagaaa gaatggctcc aaattaaagg gaaggactat tatttcaaat ccggtggtta
    18181 tctactgaca agtcagtgga ttaatcaagc ttatgtgaat gctagtggtg ccaaagtaca
    18241 gcaaggttgg ctttttgaca aacaatacca atcttggttt tacatcaaag aaaatggaaa
    18301 ctatgctgat aaagaatgga ttttcgagaa tggtcactat tattatctaa aatccggtgg
    18361 ctacatggca gccaatgaat ggatttggga taaggaatct tggttttatc tcaaatttga
    18421 tgggaaaata gctgaaaaag aatgggtcta cgattctcat agtcaagctt ggtactactt
    18481 caaatccggt ggctacatgg cagccaatga atggatttgg gataaggaat cttggtttta
    18541 cctcaagttt gatggcaaaa tggctgaaaa agaatgggtc tacgattctc atagtcaagc
    18601 ctggtactac ttcaaatccg gtggctacat gacagccaat gaatggattt gggataagga
    18661 atcttggttt tacctcaagt ctgatggcaa aatggctgaa aaagaatggg tctacgattc
    18721 tcatagtcaa gcttggtact acttcaaatc cggtggctac atggcgaaaa atgagacagt
    18781 agatggttat cagcttgaaa gcgatggtaa atggcttgga ggaaaagcta caaatgaaaa
    18841 tgctgcttac tatcaagtag tgcctgttac agccaatgtt tatgattcag atggtgaaaa
    18901 gctttcctat atatcgcaag gtagtgtcgt atggctagat aaggatagaa aaagtgatga
    18961 caagcgcttg gctattacta tttctggttt gtcaggctat atgaaaacag aagatttaca
    19021 agcgctagat gctagtaagg actttatccc ttattatgag agtgatggcc accgttttta
    19081 tcactatgtg gctcagaatg ctagtatccc agtagcttct catctttctg atatggaagt
    19141 aggcaagaaa tattattcga cagatggcct gcattttgat ggttttaagc ttgaaaatcc
    19201 cttccttttc aaagatttaa cagaggctac aaactacagt gctgaagaat tggataaggt
    19261 atttagtttg ctaaacatta acaatagcct tttggagaac aagggcgcta cttttaagga
    19321 agccgaagaa cattaccata tcaatgctct ttatctcctt gcccatagtg ccctagaaag
    19381 taactgggga agaagtaaaa ttgccaaaga taagaataat ttctttggca ttacagccta
    19441 tgatacgacc ccttaccttt ctgctaagac atttgatgat gtggataagg gaattttagg
    19501 tgcaaccaag tggattaagg aaaattatat cgatagggga agaactttcc ttggaaacaa
    19561 ggcttctggt atgaatgtgg aatatgcttc agacccttat tggggcgaaa aaattgctag
    19621 tgtgatgatg aaaatcaatg agaagctagg tggcaaagat tagtactata agtgaatatg
    19681 atttgagtga atagtaagtt aaaaatcctg atttcaagta aaatcaggat tttttcatgg
    19741 atgcaatttt tttggagtct ggtgtgacgc ggagagtctt ttgtcctgtg taagtgacaa
    19801 agccgggttt tccaccagtt ggtttattga gttttttgac ttcaatcata tctacctgca
    19861 ccagattcga caagcgccct tgagagaagt aggcagctaa ctctgctgcg tctgtcttga
    19921 ctgcatcaga tgggtcaaga tttcctgaga tgacaacatg gcttccagga atgtccttag
    19981 catggaacca aagttcctcc ttgcgagcca ttttaaaggt caattcctca ttttgaagat
    20041 tgtttcgtcc gacatagatg atggttttgc catcgcttgc tagatattgt tctagttttt
    20101 tgcgtttctg gattttctcc cgttgtcttc ttcggataaa acctgtttga atcaattctt
    20161 cacggatttc agcgatttct tccagtccag cttggttgag gacggtttct acactttcca
    20221 gatagagaat agtggctttg gtttcttcaa tcaaatcagt caagtatttg acagcttctt
    20281 tgagtttctg ataccgttta aaatagcgtt gggcattctg gttgggagtc agagccttat
    20341 caagcgcaat catgataggt tggttggtat agtagttgtc taggataacc tggtcttggt
    20401 cgttaggcac ttggtggagg aaggttgtca gcaattctcc tttttgacga aattcttcag
    20461 cgttgtctgt cgccagtaac tctttttcct gttttttgag tttgtgtcgg tttttctgaa
    20521 gttcattttc aacacgacga atcagttcac tggcctgctg tttgacgcgg tcgcgctcag
    20581 ccttatcctt atagtaggtg tccaacaaat cagaaagatt tgcaaaaggc tctcccacct
    20641 gatttgcaaa aggaactgga ctgaaggaag tctcagtcaa gcatggcttg gtttcttgat
    20701 tgaaaaaatt tcggaaagcg gaaagttttt cactaaccag tatcctttcc aattcatttg
    20761 ccgtatcgcg tcccagacct tgaaagaggc tttgaagatt ttttgctgtt agttcttggg
    20821 tttgcaggat ttcaaagagc ttttcatcct tgatagtaaa aggattgaga gattctgtac
    20881 ttggcggagc gatataggtc gatcctggaa gtaaggtgcg gtagctattt tgtgaaaaac
    20941 cgacgtgttt gataacttcg aggattttat gactgctttt atcgaccagt agaatattac
    21001 tgtgtttccc cataatttca ataatcaagg tagcctggat atggtctcca atctcgtttt
    21061 tattggaaac tgtcatttcc acaatacggt cattttccac ttgctcaatc gactcaatca
    21121 gggccccctg caaatacttt ctcaaaacca tgataaaggt agaaggttga gctggatttt
    21181 caaaagtcgt ttgggtcagc tgaatgcgtc caaaaactgg atgggcagaa aggagcaggc
    21241 gatggctttg gcgattgctg cggatttgca agaccaactc ttgttcaaaa ggctgattga
    21301 ttttctggat gcgaccattc actaattcgc ttcgcaattc ctcaactatg tggtgtaaaa
    21361 aaaatccatc aaatgacatc gttctctcct tgtgattgta ttccatagta ttatatcaaa
    21421 aaggtagaat aaaatcatgg aaatgtggta taataaagcc aagtaaagag aaacgagaag
    21481 cacatgtata ttgaaatggt agatgaaact ggtcaagttt caaaagaaat gttgcaacaa
    21541 acccaagaaa ttttggaatt tgcagcccaa aaattaggaa aagaagacaa ggagatggca
    21601 gtcacttttg tgaccaatga gcgtagtcat gaacttaatc tggagtaccg tgacaccgac
    21661 cgtccgacag atgtcatcag ccttgagtat aaaccagaat tggaaattac ctttgacgaa
    21721 gaggatttgc ttgaaaatcc agaattggca gagatgatgt ctgagtttga tgcctatatt
    21781 ggggaattgt tcatctctat cgataaggct catgagcagg ccgaagaata tggtcacagc
    21841 tttgagcgtg agatgggctt cttggcagta cacggctttt tacatattaa cggctatgat
    21901 cactacactc cggaagaaga agcggagatg ttcggtttac aagaagaaat tttgacagcc
    21961 tatggactca caagacaata aacgaaaatg gaaaaatcgt gacctgatat ccagtttaga
    22021 atttgccatc acagggattt ttactgctat caaggaagaa cgaaatatgc gaaaacatgc
    22081 agtgacggct ctagtggtta tccttgcagg ttttgttttt caggtgtcac gaatcgaatg
    22141 gctctttctc ctattgagca ttttcttggt agtagccttt gagattatca actctgctat
    22201 tgaaaatatg gtggatttgg ccagtcacta tcacttttcc atgctggcta aaaatgccaa
    22261 ggatatggcg gctggcgcgg tattagtggt ttctcttttc gcagccttaa caggtgcatt
    22321 gatttttctc ccacgaatct gggatttatt attttaaaca gtaagaggaa attatgactt
    22381 ttaaatcagg ctttgtagcc attttaggac gtcccaatgt tgggaagtca acctttttaa
    22441 atcacgttat ggggcaaaag attgccatca tgagtgacaa ggcgcagaca acgcgcaata
    22501 aaatcatggg aatttacacg actgataagg agcaaattgt ctttatcgac acaccaggga
    22561 ttcacaaacc taaaacagct ctcggagatt tcatggttga gtctgcctac agtacccttc
    22621 gcgaagtgga caccgttctt ttcatggtgc ctgctgatga agcgcgtggt aagggggacg
    22681 atatgattat cgagcgtctc aaggctgcca aggttcctgt gattttggtg gtgaataaaa
    22741 tcgataaggt ccatccagac cagctcttgt ctcagattga tgacttccgt aatcaaatgg
    22801 actttaagga aattgttcca atatcagccc ttcagggaaa taacgtgtct cgtctagtgg
    22861 atattttgag tgaaaatctg gatgaaggtt tccaatattt cccgtctgat caaatcacag
    22921 atcatccaga acgtttctta gtttcagaaa tggttcgcga gaaagtcttg cacctaactc
    22981 gtgaagagat tccgcattct gtagcagtag ttgttgactc tatgaaacga gacgaagaga
    23041 cagacaaggt tcacatccgt gcaaccatca tggtcgagcg cgatagccaa aaagggatta
    23101 tcatcggtaa aggtggcgct atgcttaaga aaatcggtag tatggcccgt cgtgatatcg
    23161 aactcatgct aggagacaag gtcttcctag aaacctgggt caaggtcaag aaaaactggc
    23221 gcgataaaaa gctagatttg gctgactttg gctataatga aagagaatac taagtagagg
    23281 taggctcatg cctgcttctt gtttttacag aaggaggact tatgcctgaa ttacctgagg
    23341 ttgaaaccgt ttgtcgtggc ttagaaaaat tgattatagg aaagaagatt tcgagtatag
    23401 aaattcgcta ccccaagatg attaagacgg atttggaaga gtttcaaagg gaattgccta
    23461 gtcagattat cgagtcaatg ggacgtcgtg gaaaatattt gcttttttat ctgacagaca
    23521 aggtcttgat ttcccatttg cggatggagg gtaagtattt ttactatcca gaccaagtgc
    23581 ctgaacgcaa gcatgcccat gttttctttc attttgaaga tggtggcacg cttgtttatg
    23641 aggatgttcg caagtttgga accatggaac tcttggtgcc tgacctttta gacgcctact
    23701 ttatttctaa aaaattaggt cctgaaccaa gcgaacaaga ctttgattta caggtctttc
    23761 aagctgccct tgccaagtcc aaaaagccta tcaaatccca tctcctagac cagaccttgg
    23821 tagctggact tggcaatatc tatgtggatg aggttctctg gcgagctcag gttcatccag
    23881 ctagaccttc ccagactttg acagcagaag aagcgactgc cattcatgac cagaccattg
    23941 ctgttttggg ccaggctgtt gaaaaaggcg gttccaccat tcggacctat accaatgcct
    24001 ttggggaaga tggaagcatg caggattttc atcaggtcta cgataagact ggtcaagaat
    24061 gtgtacgctg tggtaccatc attgagaaaa ttcaactagg cggacgtgga acccactttt
    24121 gtccaaactg tcaaaggagg gactgatggg aaaaatcatc ggaatcactg ggggaattgc
    24181 ctctggtaag tcaactgtga caaattttct aagacagcaa ggctttcaag tagtggatgc
    24241 cgacgcagtc gtccaccaac tacagaaacc tggtggtcgt ctgtttgagg ctctagtaca
    24301 gcactttggg caagaaatca ttcttgaaaa cggagaactc aatcgccctc tcctagctag
    24361 tctcatcttt tcaaatcctg atgaacgaga atggtctaag caaattcaag gggagattat
    24421 ccgtgaggaa ctggctactt tgagagaaca gttggctcag acagaagaga ttttcttcat
    24481 ggatattccc ctactttttg agcaggacta cagcgattgg tttgctgaga cttggttggt
    24541 ctatgtggac cgagatgccc aagtggaacg cttaatgaaa agggaccagt tgtccaaaga
    24601 tgaagctgag tctcgtctgg cagcccagtg gcctttagaa aaaaagaaag atttggccag
    24661 ccaggttctt gataataatg gcaatcagaa ccagcttctt aatcaagtgc atatccttct
    24721 tgagggaggt aggcaagatg acagagatta actggaagga taatctgcgt attgcctggt
    24781 ttggtaattt tctgacagga gccagtattt ctttggttgt accttttatg cccatcttcg
    24841 tggaaaatct aggtgtaggg agtcagcaag tcgcttttta tgcaggctta gcaatttctg
    24901 tctctgctat ttccgcggcg ctcttttctc ctatttgggg tattcttgct gacaaatacg
    24961 gccgaaaacc catgatgatt cgggcaggtc ttgctatgac tatcactatg ggaggtttgg
    25021 cctttgtccc aaatatctat tggttaatct ttcttcgttt actaaacggt gtatttgcag
    25081 gttttgttcc taatgcaacg gcactgatag ccagtcaggt tccaaaggag aaatcaggct
    25141 ctgccttagg tactttgtct acaggcgtag ttgcaggtac tctaactggt ccctttattg
    25201 gtggctttat cgcagaatta tttggcattc gtacagtttt cttactggtt ggtagttttc
    25261 tatttttagc tgctattttg actatttgct ttatcaagga agattttcaa ccagtagcca
    25321 aggaaaaggc tattccaaca aaggaattat ttacctcggt taaatatccc tatcttttgc
    25381 tcaatctctt tttaaccagt tttgtcatcc aattttcagc tcaatcgatc ggccctattt
    25441 tggctcttta tgtacgcgac ttagggcaga cagagaatct tctttttgtc tctggtttga
    25501 ttgtgtccag tatgggcttt tccagtatga tgagtgcagg agtcatgggc aagctaggtg
    25561 acaaggtggg caatcatcgt ctcttggttg tcgcccagtt ttattcagtc atcatctatc
    25621 tcctctgtgc caatgcctct agcccccttc aactaggact ctatcgtttc ctctttggct
    25681 tgggaaccgg tgccttgatt cccggggtta atgccctact cagcaaaatg actcccaaag
    25741 ccggcatttc gagggtcttt gccttcaatc aggtattctt ttatctggga ggtgttgttg
    25801 gtcccatggc aggttctgca gtagcaggtc aatttggcta ccatgctgtc ttttatgcga
    25861 caagcctttg tgttgccttt agttgtctct ttaacctgat tcaatttcga acattattaa
    25921 aagtaaagga aatctagtgc gagtaaaaat caatctcaaa tgctcctctt gtggcagtat
    25981 caattaccta accagtaaaa attcaaaaac ccatccagac aagattgagg ttttaaagta
    26041 ttgtcccaag gaaagaaaag taaccctaca tcttgaatct aagtagattt tatggtaaaa
    26101 taatagggat tttaaggagt ttgatatgta taacctatta ttaaccattt tattagtatt
    26161 atctgttgtg attgtgattg caattttcat gcaaccaacc aaaaaccaat ccagcaatgt
    26221 atttgatgcc agttcaggtg atttgtttga acgcagtaaa gctcgcggtt ttgaagctgt
    26281 aatgcagcgt ttgacaggga ttttagtctt tttctggcta gccattgcct tagcattgac
    26341 ggtattatca agtagataag aaaataatgg gcaggactag gtctttgcct ctttttattt
    26401 ttaaaggatg tttgagaagg ttttacagta aaagaaaatt aaaaaatcta gaaagaaaat
    26461 atgaaagata gaataaaaga atatttacaa gacaagggaa aggtgactgt taatgatttg
    26521 gctcaggctt tgggaaaaga cagttccaag gattttcgtg agttgattaa aaccttgtcc
    26581 ttaatggaaa gaaagcacca aattcgtttt gaagaagatg gtagtctgac attagaaatt
    26641 aagaaaaaac atgagattac cctcaagggg atttttcatg cccataaaaa tggctttggc
    26701 tttgttagtc tggaaggcga ggaggacgac ctttttgtag ggaaaaatga tgtcaactat
    26761 gctattgatg gtgataccgt cgaggtagtg attaagaaag tcgctgaccg caataaggga
    26821 acagcagcag aagccaaaat tattgatatc ctagaacaca gtttgacaac agttgtcggg
    26881 caaatcgttc tggatcagga aaagcctaag tatgctggct atattcgttc aaaaaatcag
    26941 aaaatcagtc aaccgattta tgttaagaaa ccagccctaa agttagaagg aacagaagtt
    27001 ctcaaggtct ttatcgataa atacccaagc aagaaacatg atttctttgt cgcgagtgtt
    27061 ctcgatgtag tgggacactc aacggatgtc ggaattgatg ttcttgaggt cttggaatca
    27121 atggacattg tatccgagtt tccagaagct gttgttaagg aagcagaaag tgtgcctgat
    27181 gctccgtctc aaaaggatat ggaaggtcgt ctggatctaa gagatgaaat tacctttacc
    27241 attgacggtg cggatgccaa ggacttggac gatgcagtgc atatcaaggc tctgaaaaat
    27301 ggcaatctgg agcttggggt tcacatcgca gatgtttctt attatgtgac cgaggggtct
    27361 gcccttgaca aggaagccct taaccgtgcg acttctgttt acgtgacaga ccgagtggtg
    27421 ccaatgcttc cagaacgact atcaaatggc atctgctctc tcaatcccca agttgaccgc
    27481 ctgacccagt ctgctattat ggagattgat aaacatggtc gtgtggtcaa ctataccatt
    27541 acacaaacag ttatcaagac cagttttcgt atgacctata gcgatgtcaa tgatatccta
    27601 gctggcgatg aagaaaagag aaaagaatat cataaaattg tattaagtat cgaactcatg
    27661 gccaagcttc atgaaacttt agaaaacatg cgtgtgaaac gtggagctct caattttgat
    27721 accaatgaag cgaagatttt agtggataaa caaggtaagc ctgttgatat cgttcttcgg
    27781 cagcgtggta ttgccgagcg gatgattgag tcttttatgt tgatggctaa tgaaacagtt
    27841 gccgaacatt tcagcaagtt ggatttgcct tttatctatc gaattcacga ggagcctaag
    27901 gctgaaaagg ttcagaagtt tattgattat gcttcgagtt ttggcttgcg catttatgga
    27961 actgccagtg agattagtca ggaggcactt caagacatca tgcgtgctgt tgagggagaa
    28021 ccttatgcag atgtattgtc catgatgctt cttcgctcta tgcagcaggc tcgttattcg
    28081 gagcacaatc acggccacta tggactagct gctgactatt atactcactt taccagtcca
    28141 attcgtcgtt atccagacct tcttgttcac cgtatgattc gagattacgg ctgttctaag
    28201 gaaatagcag agcattttga acaagtgatt ccagagattg cgacccagtc ttccaaccgt
    28261 gaacgtcgtg ccatagaagc tgagcgtgaa gtcgaagcca tgaaaaaggc tgagtatatg
    28321 gaagaatacg tgggtgaaga gtatgatgca gttgtatcaa gtattgtcaa attcggtctc
    28381 tttgtcgaat tgccaaacac agttgaaggc ttgattcaca tcactaatct acctgaattt
    28441 tatcatttca atgagcgtga tttgactctt cgtggagaaa aatcaggtat cactttccga
    28501 gtgggtcagc agatccgtat ccgtgttgaa agagcggata aaatgactgg agagattgat
    28561 ttttcattcg tacctagtga gtttgatgtg attgaaaaag gcttgaaaca gtctagtcgt
    28621 agtggcagag ggcgtggttc aaatcgtcgt tcggataaga aggaagacaa gagaaaatta
    28681 ggacgctcaa atgataagcg taagcattca caaaaagaca agaagaaaaa aggaaagaaa
    28741 cctttttaca aggaagtagc taagaaagga gccaagcatg gcaaagggcg agggaaaggt
    28801 cgtcgcacaa aataaaaagg cacgccacga ctatacaatc gtagatacgc tagaggcagg
    28861 gatggtcctg actggaactg aaatcaagag tgtacgagct gctcgaatta atctcaagga
    28921 tggctttgct caagtgaaaa atggagaagt ttggctgagc aatgttcata tcgcgcctta
    28981 cgaagagggc aatatctgga accaggaacc agaacgtcgt cgtaaactcc tgcttcataa
    29041 aaagcaaatt caaaaattgg aacaagagac caaagggaca ggaatgacct tagttcccct
    29101 taaggtctat ataaaagatg gctacgctaa gcttctttta ggacttgcca aagggaagca
    29161 tgactatgac aaacgggagt ctatcaaacg tcgtgagcaa aatcgagata tcgcgcgtgt
    29221 gatgaaagct gttaatcagc gataaaaaga ggaattgaaa atggaaaaat tagttgccta
    29281 taaacgcatg cctttgtgga ataaacaaac aatgcctgaa gctgttcagc aaaagcacaa
    29341 tacaaaagtt gggacttggg ggaaaattac tgtcttgaag ggagctctca agtttattga
    29401 attgacagaa gaaggggaag ttctagctga acacctcttt gaagcagggg cagacaatcc
    29461 aatggcccaa cctcaagcct ggcaccgagt ggaagctgcc acagatgatg tggaatggta
    29521 cttggaattt tattgtaaac ctgaggatta ttttgctaaa aaatacaata ccaatcctgt
    29581 tcattcagag gtcctagagg ccatgcagac agtgaaacaa gggaaagctt tggatttggg
    29641 ttgtggtcag gggcgtaatt ctctttttct agcccagcaa gattttgatg tgacggctgt
    29701 agatcaaaat ggactagctc ttgaaatctt gcaaagcatt gtggagcagg aagatttgga
    29761 catgcctgtt ggcctttacg atatcaattc agctagcatt gaacaagaat atgattttat
    29821 cgtttcaaca gttgttctca tgtttctaca agcggaccgc attccagcta ttattcaaaa
    29881 tatgcaggag aaaaccagtg ttggtggtta caaccttatc gtttgtgcca tggacacgga
    29941 ggattatcct tgctcggtta acttcccatt cacctttaaa gaaggagaac tggcagacta
    30001 ttacaaggat tgggaattgg ttaagtacaa tgaaaatcca ggccatttgc accgtcgcga
    30061 tgagaatggc aatcgtattc aactacgctt tgcgacctta ctagctaaga aaatcaagta
    30121 aacacacatg aagattagga attttcctga tcttttttct tttttacgaa tgatatagaa
    30181 aaggagggaa ttcatgtttg ttgcgagaga tgctagggga gaattggtaa atgtgttaga
    30241 ggataaactt gagaagcaag catacacctg cccagcttgt ggaggccagc tccatttgcg
    30301 tcaaggacca agtgtacgga cgcattttgc ccataaatcc ttaaaagact gtgatttttt
    30361 ctttgaaaat gaaagtccag aacacctggc caataaggaa tccctctatc actggttgaa
    30421 aaaagagaca aaggttcaat tagagtaccc gctttcagaa cttaaacaga ttgcggatgt
    30481 atttgtaaat ggcaatctag ctctagaagt tcagtgtagt cccttgcctc agaaagtcct
    30541 taaagagcga agtgagggct atcgtagtca gggttaccaa gtactgtggt tgctgggtca
    30601 aaaactgtgg ctcaaggagc gtttgactcg tctacagcaa ggttttcttt atttcagtca
    30661 aaacatgggc ttttatgttt gggaattaga caagggaaaa caagttttaa gactcaaata
    30721 cctgatttac caggatctcc gcggtaaact ccattatcaa atcaaggaat tttcctatgg
    30781 ccaaggtagt ttattggaaa tattgcgtct tccctataag aaacaaaaaa tatctcattt
    30841 tacagtttct gaggacaagg acatctgtcg ctatatccgg caacaacttt attatcaaaa
    30901 tctcttttgg atgaaagaac aagcagaagc ctatcaaaag ggagaaaata tcctgactta
    30961 tggactgaaa gaatggtatc cacaaattcg accaatagtg ggcaaatttt tccagattga
    31021 acaagacttg actagctatt atcagcactt ttatacctat taccaaaaaa atcctcaaaa
    31081 tgattggcaa aagctttatc caccagcctt ttatcagcaa tatttcttga aaaatatggt
    31141 agaatagaaa ggatggagga atctaatggt attacaaaga aatgaaataa atgaaaaaga
    31201 tacatgggat ctatcaacga tctacccaac tgatcaggct tgggaagaag ccttaaaaga
    31261 tttaacagaa caattggaga cagtagccca gtatgaaggc catctcttgg atagtgcgga
    31321 taacctacta gaaatcactg aattttctct tgaaatggaa cgccagatag agaagcttta
    31381 cgtttatgct catatgaaga atgaccagga tacacgtgaa gctaagtatc aagagtacta
    31441 tgccaaggcc atgacactct acagccagtt agaccaagcc ttttcattct atgagcctga
    31501 atttatggag attagcgaaa agcagtatgc tgacttttta gaagctcaac caaagctgca
    31561 ggtttatcaa cactattttg acaagctctt gcaaggcaag gatcatgttc tttcacaacg
    31621 tgaagaagaa ttattggctg gagctggaga aatctttggt tcagcaagtg aaaccttcgc
    31681 tatcttggac aatgcggata ttgtgttccc ttatgtccta gacgatgatg gtaaagaagt
    31741 tcagctatct catgggactt acacacgttt gatggagtct aaaaaacgtg aggttcgccg
    31801 tggtgcctat caagctcttt atgcgactta cgaacaattc caacacacct atgccaaaac
    31861 cttgcaaacc aatgttaagg tgcaaaatta ccgtgctaaa gttcgtaact acaagagtgc
    31921 tcgtcatgca gccctcgcag cgaattttgt tccagaaagt gtttatgaca atttggtagc
    31981 agcagttcgc aagcatttgc cactcttaca tcgctatctt gagcttcgtt caaaaatctt
    32041 ggggatttca gatctcaaga tgtacgatgt ctacacaccg ctttcatctg ttgaatacag
    32101 ttttacctac caagaagcct tgaaaaaagc agaagatgct ttggcagtct tgggtgagga
    32161 ttacttgagc cgtgttaaac gtgccttcag cgagcgttgg attgatgttt acgaaaatca
    32221 aggcaagcgt tcaggtgcct actctggtgg ttcttacgat accaatgcct ttatgcttct
    32281 caactggcag gacaatctgg acaatctctt tactcttgtt catgaaacag gtcacagtat
    32341 gcattcaagc tatactcgtg aaactcagcc ttatgtttac ggagattact ctatcttttt
    32401 ggctgagatt gcctcaacta ccaatgaaaa tatcttgacg gagaaattat tggaagaagt
    32461 ggaagacgac gcaacacgct ttgctattct caataacttc ctagatggtt tccgtggaac
    32521 agttttccgc caaactcaat ttgctgagtt tgaacacgcc attcaccaag cagatcaaaa
    32581 tggggaggtc ttgacaagcg atttcctaaa taaactctac gcagacttga accaagagta
    32641 ttatggtttg agtaaggaag acaatcctga aatccaatac gagtgggctc gcattccaca
    32701 cttctactat aactactatg tatatcaata ttcaactggc tttgcggccg cctcagcctt
    32761 ggctgaaaaa attgtccatg gtagtcaaga agaccgtgac cgctatatcg actacctcaa
    32821 ggcaggtaag tcggactatc cacttaatgt catgagaaaa gctggtgttg atatggagaa
    32881 ggaagactac ctcaacgatg cctttgcagt ctttgaacgc cgtttaaatg agtttgaagc
    32941 ccttgttgaa aaattaggat tggcataaaa tggttgaatc gtatagtaag aatgctaacc
    33001 ataacatgcg tcgtcctgtc gtcaaagaag aaattgtaga cttgatgcgt cagcgtcaaa
    33061 agcaggtcac aggtttcttg aaagaattgg aagactttgc ccgcaaggaa aatattccta
    33121 ttattcccca tgaaacggtt gcttatttcc gttttcttat ggaaaccatg cagcctaaaa
    33181 atattctgga aattgggacg gctatcggtt tttcagctct cttgatggct gaacatgcgc
    33241 caaatgctaa gattacaact attgatcgta atccagaaat gattggtttt gccaaggaaa
    33301 attttgccca gtttgacagt cgcaagcaaa tcactctctt agagggagat gcggtggatg
    33361 tcttatctac actgacagag tcttatgatt tcgtatttat ggattctgcc aagtctaaat
    33421 acatcgtctt tctgccagaa atcctcaaac atttggaagt tggtggtgtg gttgtcttgg
    33481 atgatatttt tcaaggtggt gatgttgcca aggatattat ggaagtccgt cgtggtcagc
    33541 gaaccattta tcgaggcctt caaaaattat ttgatgcaac cttagacaat ccagaactca
    33601 ccgcaacatt agtgccttta ggagatggta ttctcatgct tcgtaaaaat gtagcagatg
    33661 ttcaactgtc tgaaagcgaa tgattttcag aaaaatttaa gaaaaaatag taaaatagat
    33721 agagtaacac ttatctcaaa ggagtagaca tgaagaaaaa attattggca ggtgccatca
    33781 cactattatc agtagcaact ttagcagctt gttcgaaagg gtcagaagga gcagacctta
    33841 tcagcatgaa aggggatgtc atcacagaac atcaatttta tgagcaagtg aaaaacaacc
    33901 cttcagccca acaagtcttg ttaaatatga ccatccaaaa agtttttgaa aaacaatatg
    33961 gctcagagct tgatgataaa gaggttgacg atactattgc cgaagaaaaa aaacaatatg
    34021 gcgaaaacta ccaacgtgtc ttgtcacaag caggtatgac tcttgaaaca cgtaaagctc
    34081 aaattcgtac aagtaaatta gttgagttgg cagttaagaa ggtagcagaa gctgaattga
    34141 cagatgaagc ctataagaaa gcctttgatg agtacactcc agatgtaacg gctcaaatca
    34201 tccgtcttaa taatgaagat aaggccaaag aagttctcga aaaagccaag gcagaaggtg
    34261 ctgattttgc tcaattagcc aaagataatt caactgatga aaaaacaaaa gaaaatggtg
    34321 gagaaattac ctttgattct gcttcaacag aagtacctga gcaagtcaaa aaagccgctt
    34381 tcgctttaga tgtggatggt gtttctgatg tgattacagc aactggcaca caagcctaca
    34441 gtagccaata ttacattgta aaactcacta agaaaacaga aaaatcatct aatattgatg
    34501 actacaaaga aaaattaaaa actgttatct tgactcaaaa acaaaatgat tcaacatttg
    34561 ttcaaagcat tatcggaaaa gaattgcaag cagccaatat caaggttaag gaccaagcct
    34621 tccaaaatat ctttacccaa tatatcggtg gtggagattc aagctcaagc agtagtacat
    34681 caaacgaata gtccaaatca atgagtcagg gaaaaaaact cgacttcagg aaaaaatgaa
    34741 gcaaacattc ccacaataaa acgcatagta caaggtttgt actgacccca aaagttagac
    34801 aattaattta tctgaaggat ttagttctgt attgcacagg gctaagtcct tttagtttta
    34861 ccttaattct cttattgttg taataatcaa tatagtctat aatggcttgt tccaattgat
    34921 taagtgattt aaatgttttc tcatagccat aaaacatttc ggattttaaa atgccaaaga
    34981 aagattccat cctaccgttg tcttggctgt ttcctttgcg tgacatagat gcttgaattc
    35041 ccttactctc taggaagcga tgataagaat cgtgttggta ttgccagcct tggtcactat
    35101 ggagaatcgt attctcgtag tgcttctctt tgaatgcctg ttccaacatt aacgatcaat
    35161 caatttaatc atgtacctaa
//
LOCUS       DAVHBD010000020        34869 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000020 DAVHBD010000000
VERSION     DAVHBD010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.020"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..653)
                     /locus_tag="VVK04_001037"
     CDS             complement(<1..653)
                     /locus_tag="VVK04_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU3989702.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFATKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKS"
     gene            1277..1459
                     /locus_tag="VVK04_001038"
     CDS             1277..1459
                     /locus_tag="VVK04_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU3989703.1"
                     /translation="MANNNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1469..1834
                     /locus_tag="VVK04_001039"
     CDS             1469..1834
                     /locus_tag="VVK04_001039"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU3989704.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            1831..3021
                     /locus_tag="VVK04_001040"
     CDS             1831..3021
                     /locus_tag="VVK04_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU3989705.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3097..4659)
                     /gene="guaA"
                     /locus_tag="VVK04_001041"
     CDS             complement(3097..4659)
                     /gene="guaA"
                     /locus_tag="VVK04_001041"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU3989706.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4801..5499
                     /locus_tag="VVK04_001042"
     CDS             4801..5499
                     /locus_tag="VVK04_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU3989707.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(5542..6438)
                     /locus_tag="VVK04_001043"
     CDS             complement(5542..6438)
                     /locus_tag="VVK04_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU3989708.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMILAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(6447..7382)
                     /locus_tag="VVK04_001044"
     CDS             complement(6447..7382)
                     /locus_tag="VVK04_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU3989709.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKVGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(7379..8104)
                     /locus_tag="VVK04_001045"
     CDS             complement(7379..8104)
                     /locus_tag="VVK04_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU3989710.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(8188..8823)
                     /locus_tag="VVK04_001046"
     CDS             complement(8188..8823)
                     /locus_tag="VVK04_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU3989711.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRANEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(8825..9652)
                     /locus_tag="VVK04_001047"
     CDS             complement(8825..9652)
                     /locus_tag="VVK04_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU3989712.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAKTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9674..10009)
                     /locus_tag="VVK04_001048"
     CDS             complement(9674..10009)
                     /locus_tag="VVK04_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEU3989713.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEGGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(10010..10726)
                     /locus_tag="VVK04_001049"
     CDS             complement(10010..10726)
                     /locus_tag="VVK04_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEU3989714.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWFKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            11249..11860
                     /locus_tag="VVK04_001050"
     CDS             11249..11860
                     /locus_tag="VVK04_001050"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU3989715.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11905..12633
                     /gene="rlmB"
                     /locus_tag="VVK04_001051"
     CDS             11905..12633
                     /gene="rlmB"
                     /locus_tag="VVK04_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU3989716.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12672..13583)
                     /gene="trxB"
                     /locus_tag="VVK04_001052"
     CDS             complement(12672..13583)
                     /gene="trxB"
                     /locus_tag="VVK04_001052"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU3989717.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13649..13873)
                     /locus_tag="VVK04_001053"
     CDS             complement(13649..13873)
                     /locus_tag="VVK04_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU3989718.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13951..14694)
                     /locus_tag="VVK04_001054"
     CDS             complement(13951..14694)
                     /locus_tag="VVK04_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU3989719.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14694..15494)
                     /locus_tag="VVK04_001055"
     CDS             complement(14694..15494)
                     /locus_tag="VVK04_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU3989720.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15652..16008)
                     /locus_tag="VVK04_001056"
     CDS             complement(15652..16008)
                     /locus_tag="VVK04_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU3989721.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(16002..16532)
                     /locus_tag="VVK04_001057"
     CDS             complement(16002..16532)
                     /locus_tag="VVK04_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU3989722.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(16532..17026)
                     /locus_tag="VVK04_001058"
     CDS             complement(16532..17026)
                     /locus_tag="VVK04_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989723.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            17161..17607
                     /locus_tag="VVK04_001059"
     CDS             17161..17607
                     /locus_tag="VVK04_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU3989724.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            17604..18251
                     /locus_tag="VVK04_001060"
     CDS             17604..18251
                     /locus_tag="VVK04_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU3989725.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(18272..18853)
                     /gene="pdxT"
                     /locus_tag="VVK04_001061"
     CDS             complement(18272..18853)
                     /gene="pdxT"
                     /locus_tag="VVK04_001061"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU3989726.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILAIVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18854..19729)
                     /gene="pdxS"
                     /locus_tag="VVK04_001062"
     CDS             complement(18854..19729)
                     /gene="pdxS"
                     /locus_tag="VVK04_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU3989727.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRANAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19881..21260)
                     /locus_tag="VVK04_001063"
     CDS             complement(19881..21260)
                     /locus_tag="VVK04_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU3989728.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            21554..22477
                     /locus_tag="VVK04_001064"
     CDS             21554..22477
                     /locus_tag="VVK04_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU3989729.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            22537..23142
                     /locus_tag="VVK04_001065"
     CDS             22537..23142
                     /locus_tag="VVK04_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU3989730.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            23161..24405
                     /locus_tag="VVK04_001066"
     CDS             23161..24405
                     /locus_tag="VVK04_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU3989731.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGNADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24522..24779)
                     /locus_tag="VVK04_001067"
     CDS             complement(24522..24779)
                     /locus_tag="VVK04_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU3989732.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEKGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24821..26857)
                     /locus_tag="VVK04_001068"
     CDS             complement(24821..26857)
                     /locus_tag="VVK04_001068"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU3989733.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(27069..27986)
                     /gene="glyQ"
                     /locus_tag="VVK04_001069"
     CDS             complement(27069..27986)
                     /gene="glyQ"
                     /locus_tag="VVK04_001069"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU3989734.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(28354..29115)
                     /locus_tag="VVK04_001070"
     CDS             complement(28354..29115)
                     /locus_tag="VVK04_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU3989735.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYSWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(29388..30230)
                     /locus_tag="VVK04_001071"
     CDS             complement(29388..30230)
                     /locus_tag="VVK04_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU3989736.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQARQAFEESLEKLGLDYLD
                     LYLIHWPNPKPLRENDQWKIRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(30344..31735)
                     /locus_tag="VVK04_001072"
     CDS             complement(30344..31735)
                     /locus_tag="VVK04_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU3989737.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31970..32347)
                     /locus_tag="VVK04_001073"
     CDS             complement(31970..32347)
                     /locus_tag="VVK04_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU3989738.1"
                     /translation="MLCQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLASHSFIVK"
     gene            32580..33557
                     /locus_tag="VVK04_001074"
     CDS             32580..33557
                     /locus_tag="VVK04_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU3989739.1"
                     /translation="MLKLGIIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAKKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            33554..34636
                     /locus_tag="VVK04_001075"
     CDS             33554..34636
                     /locus_tag="VVK04_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU3989740.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34700..>34869)
                     /locus_tag="VVK04_001076"
     CDS             complement(34700..>34869)
                     /locus_tag="VVK04_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU3989741.1"
                     /translation="EQVLKEIHKRGFKNKAFRTLEDVMNQLQDVIQGLEKEVIKSIVN
                     RKWTRMLFESR"
BASE COUNT        10579 a         7647 c         6216 g        10427 t
ORIGIN      
        1 aaactcttac gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac
       61 tgagaacatc caccacggtt ggcatcacgc atactcatgt ggtttgaaag agtacaacgt
      121 ccagagtatg aaatacacat agctccatgg acaaaggctt caatttcaac atctgtacgt
      181 ttgcggattt cagctaattc ttccattgaa acctcacgcg ctaaaacgac acgagtcaag
      241 cctagctctt tccagaactc aagggtttca tagttagtgg cactggcttg ggtagaaagg
      301 tggatttcaa ggcctggtgc ttcagtcgct gcaatcataa tcaaggctgg gtcagatacg
      361 ataactgctg caatcccgat atcacgcagt ttacggaacc actcaccagc accagcttca
      421 tttccttcgt gcataaccat attagccgct acatagacct tggcaccata cttggtcgca
      481 aactgcacgc cttcttccat ctgttcgaaa gtaaagtttc ccgcacggct acgaagacca
      541 taggcctgac caccgataaa gacagcatct gctccatact gaacagctac ctttagcttc
      601 tctaaagtcc ctgcaggtga taaaacctca ggacgtttta atgtttttgt catgatttct
      661 cctatttgca atataaaagt ttgacatttt tccttctcat tttatagtaa ataaaggata
      721 aaatcaagcc tagacggatt gttttgacaa ttctaatctt ttagactttg cataataact
      781 attaaacagt cgaaaattac cccagtttta acaagtagtc aaaaagtcta aaaaagtaaa
      841 aaccagtatc ccaagatact gactcgtaaa aatatataaa ttagtcctta gatgactact
      901 cccactctgt tgctcctata atggaaaagg attgatacag tctagaatat cactttttta
      961 tttattattc tgatataaaa ctgttagaat tgattctttg ttttataccc aaatatgaat
     1021 agagacgtag ttaataagtt gaataacata tttggaaaaa tgagaaatag caatattact
     1081 agaactttta gaaacaatca atatttaaaa agaaaaaagc tcaaagaatt tattaaacca
     1141 tgttataata gatatagcta taattttatt tataacaaga ggatagaaat gaccgaatta
     1201 gaaagaaaaa atcgaaaaat tagctaagaa atattctgat aacttaaaca tcaaagttca
     1261 agagagagtt cgtgaaatgg caaataataa taagagccat tatttgatat acagagtttt
     1321 aggtatttca tttgaagaag gagaaaatat cgatttgtat caaaataaag gtcgtttttt
     1381 atacaaatat gctggttcat ttttagaaga agctgcagta ctatccttta acgaaaaatt
     1441 tggtacagaa aatacttaaa aagttaacat tcctaattct gaaagtacaa aacctaagac
     1501 ttttgaaatt gattgtttag tcggagaaaa acacgcatac gaaataaaat ggtgggatgc
     1561 aactacagat ggagaccata taactaaaga acacactaga ataaaagtta ttcataacaa
     1621 aggatatata ccaattcggt taatgttcta ctatccaaat agaactcaag ctataaaaat
     1681 tcagcaaact ttagaaacat tgtataacgg tattggaggg aaatattatt atggagattc
     1741 tgcctgggaa catttaagag cagtgaccgg tattgattta cttagtattc taacagatat
     1801 tgcaaataaa aaaacagggg taaaatcaaa atgacagtat taaaaggaga taacttagaa
     1861 atattaaaaa ctattgaatc ctcaagtatt gatttaatct atatggaccc tcctttcttt
     1921 acacagaaaa cccaaaaatt atctaataac aaaaatatta tgtattcatt cgaagatacg
     1981 tggacttcga ttgaggatta caaagaattt ttgtctgtaa gattagaaga atgcaaaaga
     2041 gtgctaaaaa atagtggcag tattttcgtt cattgtgata aaattgcaaa tcatcatatt
     2101 agattaattt tagataatat ctttggagca gatatgtttc aaagcgaaat tatatggaac
     2161 tataaacggt ggtctaattc aaaaaaggga ttattgaaca atcatcaaaa catttacttt
     2221 tattcaaagt caaaagattt taaatttaat acaattttta cagagtattc ttctactaca
     2281 aatatcgacc aaatactagt agaacgaaaa cgaaatggaa actctaaaac tatatataag
     2341 gttgataata atggtaacta tattctggca aaagagaaaa atggagttcc cctttcagat
     2401 gtttggaata taccatttct taatccaaaa gctaaagaaa gagtaggtta tcctacacaa
     2461 aaacctattc tgttattaga acaaattata aagattgcta ctgataaaaa tgatatagtt
     2521 ttagacccgt tctgtggaag tggaactact ttagtagcct ccaagatttt gaatagaaat
     2581 tatatgggga ttgatttatc tgaggaagct atcaatataa ctcagcaacg tctggaaaat
     2641 gttataaaaa caagttcaga tttattgaat aaaggaatcg aagcatatag aaccaaaact
     2701 gaggaagagg aaaacattct taaattatta caggcaaaaa ttgttcaaag aaataaagga
     2761 attgatggtt ttttacctaa acattttcaa aaaaaaccga tacctataaa aattcaaaaa
     2821 aataatgaat gtctgaatga gagtatctct ttattacaga atgctataaa ctccaaaaaa
     2881 cttgattttg gagtagttat aaaaactcat tcagataatt tattatttga ttttgatacg
     2941 attcctgaaa atataatagt agttgaccat tttgaactta caatcgaaaa atggttaagt
     3001 aaaagtcaac agttactata gtttgcaaat tatttacaga aagaacaaaa aatgctctga
     3061 aacactgatt tcaaggcatt ttttgttagt ttaaaattac tcccactcaa ctgttgcagg
     3121 tggtttactt gtaatatcgt agacgatacg gttaacatga tccacttcat ttacgatacg
     3181 tactgagatt ttttgaagta cttcccatgg aattttggca aaatcagcag tcataccatc
     3241 gatagaagtg atagcacgga ttgcaatcgt gtagtcatac gtacgaccgt cacccataac
     3301 accgactgaa cgaacgcctg tgttaacagt gaagtattgc caaatatcgc ggtcaagtcc
     3361 agctttagcg atttcttcac gaagaatagc gtctgattca cgaacggttt caagtttctc
     3421 ttcagtgatt tcacccatga cacggatagc aagtcctggt cctgggaatg gttggcgcca
     3481 tacgatatgg tctggcatac caagctctgt accaagagca cgaacttcat ccttgtaaag
     3541 agtattgagt ggttcaatca attcaaactg catatcttct ggaagaccac ccacgttgtg
     3601 gtgtgacttg atagtttgag ctgtatccgt accagactcg ataacatctg tatataaagt
     3661 accttgagca aggaatttca catctttgag cttgcttgct tcgtcatcga atacatagac
     3721 aaactcgtta ccgatgattt tacgtttttg ttcaggatca gaaacgccag caagtttgtc
     3781 aaggaaacgt ttagcagcgt ctgctttgac gatattcaaa ccaaacttac caccgagcat
     3841 gtccataact tgatcagctt cgcctttacg aagaagaccg tggtctacga agatacagat
     3901 caattgatcg ccaatcgctt tttggagaag aaccccaacg acagatgagt caacaccacc
     3961 tgatagacca agaaggacac gtttatcacc gacggtttca cgaatttttt tgatctgcat
     4021 atcaatgaaa ttatccattg accagtcacc tttagcctta caaatgttaa gggcaaagtt
     4081 acgaaggata tcatttccgt atacagaatg acgaacttct gggtggaatt ggataccgta
     4141 aatgtgttta tctgggtttt cgatggctgc gtatgggcag tcagctgatg tacctgtacg
     4201 aacaaagtca gcaggaatct cagtaaccgc atcaccatgg ctcatcaaaa cagtctgttc
     4261 atcaggtgtt gattcaaaaa gcgctgatgg tgtgtgagtt agggttgatt gaccgtattc
     4321 acgatttcca gcatcacctg caggaacaac ttttcctcca agtttatggg tcaataactg
     4381 cataccataa cagattccca aaattggaat tcctagttcg aagatttctg ggtcaatatc
     4441 aaatgaacca tcttcatata cagaatttgg accacctgat agaataattc ctacaggatt
     4501 gacttcacga acttcagcag ctgaaatttt atggcttttt agttctgaaa aaacaccaat
     4561 ctcacggata cggcgtgaaa tcagctggtt gtactggcta ccatagtcca atacgatgat
     4621 tttttctaca tcttgcaaat cagttgaaat gttgctcatc tttttccttt ctcaaaagaa
     4681 atatcttttc tcaatattct atcacaaata agggcgaatt accaactaaa caaggcgaag
     4741 tttgactttt tctagtttat tggggtacaa tagagaaaag atagaaatga agtgaaaaat
     4801 atgctacctg cttatatgaa aatccatgat cagataaaaa aggatattga cgagcaccgt
     4861 tgggctattg gtgagaggct tcccagtgaa agagatttag ctgagcagtt tgcggtcagt
     4921 cgcatgaccc tccgccaagc cgtatctcta ttagtcgaag aaggcgtctt agagcgccgt
     4981 gtaggaagcg gcacctttgt ttccagtact cgagtacaag aaaagatgcg agggacaacc
     5041 agttttactg aaattgtcaa atcccaaggt aaagttccct ctagccagct catttcctac
     5101 aaaaaaacca ttcccaatga gcaagaagtt gccaagctag gaatttttcc aacggacaat
     5161 attatccgaa tggagcgggt ccgctatgcc gaccaggttc ccctagttta tgaagttgct
     5221 tctattcctg aaaaattcat taaggacttt aaaaaagaag aaatcacaag tcatttcttc
     5281 caaaccttgc aaaaacatgg ctatcgtatc ggcaaatctc aacagaccat ctatgctcgc
     5341 cttgctaaag aaaagattgc ccactatttg gaagttgaaa aaggacatgc tattcttgga
     5401 ttgacccagg tttcctacct agaagatggt actgcttttg aatacgtaaa aagtcaatat
     5461 gtaggcgaac gctttgaatt ttatcttgaa aataattaga ttaccacgca aaaactctct
     5521 gtcacggaca aagagtcttt tttatttttc taagaataaa tctttcaaag aaatcaaagt
     5581 tacagcaaac aatatcattg ccataccaag aaaatcaatg ggataaaatt gttcattcat
     5641 tattaagaag gcaaagaaaa tcgccgatat tggctcaatt gaagccaaca agcttgactt
     5701 gaccggtcct atcagactgg ctcctttaag gaaagctgta taggcaaaga cagtcccgat
     5761 aaggataatg cctgcaaacg caaggagaaa atcaagacta gtcgggatat cggcctgtag
     5821 aacccctgta aaaggaaggg cgaccaaacc tgctatgacc attcccacac caatgaccaa
     5881 gctgctcccc cactttttaa tcaaggctat gggtaaaatg atatacagag cataagtcaa
     5941 ggcagaaaag agaccccaga acagaccagc aggtgtcatg gataactggt ccaactgccc
     6001 atgtgttgcg atcaggaagg ttcctccgat ggcgaatatg atggaaacta tctctcccag
     6061 tgtcggtgcc accctatcct tgatacagct ataaattaaa attccgacag gacaaacata
     6121 ctgaagcacc gtcgctgttc ccgcattggt ctcctgaata gcagacagat aggcgaattg
     6181 gttgagaaaa agaccaatca gagcaaaaat aagaagagac agcaaactct ttctatcctt
     6241 taaaaagacc agtattttat cctttgcagt agcataagcc aagatcatga gaattccacc
     6301 agcgattaaa agacgcaagt tggtcaagac cagagccgaa attccgtgtg ccattaggta
     6361 ttggccactc gttcctgaca acccccaagc aataccagcc acaactgtta gtaaagtccc
     6421 ttttaaacta tttgacatgt ctctccttac tcttctttac gaatcaagtt catcacttga
     6481 ttgcggtcta atatccattg agctctctcg tccttttcat aggtacgatt cgataggaaa
     6541 atagtggctt cttgcttctg acgattccac atgataaagg tacctgtata gcccgtatgg
     6601 tctagccaat ctccttccaa attccatgct aaagaacgtt ccttgtcatc caaaggagaa
     6661 aaattttgat ttaagtctct tgcaaaatca tctgctaaat agtgttctaa aaagatttgt
     6721 aaatccttta tagtcgaaaa taaaccagca ctcccagcat gtctacccag gagacgagcc
     6781 ttgggatcat gcactatgcc tgcctctaca cctctaactg ttggaacagc aagctcaact
     6841 ggcccaacct tggtttccgt cattccccaa ggtttccaga cttgatcctt taaaatcaca
     6901 tccaaatctt gattaaaaat tctttccaaa ataaagccca acagcaaaaa atggacatcc
     6961 gaataaagaa aggctggctg acttcgtctg ttgagatgaa acatcgcttc ctttaattca
     7021 ggggctgtta aaagatcacg attaggaata aaaggatcaa ggtctgttgc atgagtcaag
     7081 agctggcgaa tagtgatgtc tggataatca ctctcaggta aaaaatctat taccagtcta
     7141 tcaatatcta attgacctat ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc
     7201 ttactgacac tagctaggtc ataaactagt cctgcctcag tctgcaagcc atgctctggg
     7261 tcactctggc ctaaatagaa ctctgtccat tgattgtcct taaaatacgc aaaagaggct
     7321 ccgggataaa ttcctgcctc gatttgttct tctatttttt taataatctt ggtccacttc
     7381 atacttcttc aaaccacaat tcaacattat ttctatcttt acaaaggaag aatttttcag
     7441 acttaggaat aaaatattca gtagactcaa acttctggcg aagacttgct atgtctaatt
     7501 cattgaccaa gaacttgagc atagataagt cccaggtaac cgtattgtcc acagtcaaat
     7561 cctgcccctg agctggaata aaatcaaggg atgccccaat ttcagatgat tccaagaaac
     7621 tttcgatatc agttgggaga tgtaattcca tagaaatctc aaatttactt aaagaaattg
     7681 atgccaaatc tgtttgaaat tcaggctttt ctcctacttc tactagactt gctctgtcat
     7741 cttccgcatg aatcaaaatc aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat
     7801 tttgaccttt atataatcga tgaatcgaat ctgttttaga taagattcct tcaatttcta
     7861 agggattttc caccttgaca atcaatctag ctagtttttt tcttccctct accttacgag
     7921 tacgcatact gggagcttct tctaaaacca gcttttcaag acccgtttgg tcacctagtg
     7981 acagaaaggc cgattcttct aacaaggcct tcattccaag ggtttcaata taaaatgttt
     8041 catttaattt tctattatta gcttttaaag taggaataat ccgtacaatc tgatttacat
     8101 tcataaattc ctccgtcact ttttatttta aaggatttta gaatttttta caagatatta
     8161 tgctcaaatt taacattatt tagctattta gtaaagatag tctttcaagg attttgacaa
     8221 agcctgataa ccagcaatac tgaggtgcag tccatcagtt gtatattctt ttttgagttg
     8281 gcctgcttgg tctgtcaaac aatcaaatac tggcacaaat tccacctgca tataggcaga
     8341 tgcaagctct tgataggctt gattccagtt ctgaattttt tcattcgcgc ggatatagac
     8401 tgcctgctgg tactcctctc cctcattgac aggcaaaatg gaaagcaatt taatctctgt
     8461 caatggataa tcgcgagcaa cggattgaat gatagcttcg agattattga gagcctcatt
     8521 cacaggaaca tcctttccga tatcatttgt cccaatcaga agaaaaattt tatctactgc
     8581 tccaccatat agatgagcat caagattctc tagtaacagt cctgtctgat agccacgaat
     8641 tcctcgattg acaatcgtct ttgaagtccc aaatagctcc tgtagaggat aatactcgac
     8701 aatggaatcc ccaataaaaa gaatgtttgg ttctacaaca gaaatgtgat ttaggtgacg
     8761 atacttagtt tgaatttttt cttgttcctt taggagccaa ttttctaata actgtactgc
     8821 cacttcattc tcctttttct aaccagtttt ccaagacttg ataaactcct ccttggctgt
     8881 tggctggtgc tagagcagtc gccacagctt tggctttctc atcagcattt tccatcgcat
     8941 aggcaattcc agccatttca agcatttcaa catcattttc actatcacca aaagccatga
     9001 tttcttggga tttcaagtcc cagcgcttga gtaattcctc caagccccat gctttatgaa
     9061 tcccagcttg gaggatatca atgcaaccat agccactgga tacagctcgg acacggccat
     9121 caaagagagc attgatttct tccaaaaccg aactcaaacg ttcctcacca acaaccatgc
     9181 tcatcttgag cacaccacca aagaggtcag atgttaattc atccacaaat tgcatccgtt
     9241 ggtagaattt ttcaatcatt tctggagtca taaaactttc aagatctgta aaaatcgtac
     9301 cttccttgac aaaatcaccc ttcatccccg ttacaacaaa ctggtcctga cacgctcgac
     9361 ccttgaaatg agccaaagcc ttgttgacaa tggcgtcatc ccatgtctta gcctgaatca
     9421 attcattgtt ttcaaaaata cgagcgccat tagcaacaac cagaaccact cgatccacca
     9481 agggactcag tagttgtctc atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa
     9541 tgcccctttg atccaactga tctaaaatct tttccaatcg tgggagatca agctgacctc
     9601 tagcatccag caaggtccca tccatatctg tcgcaattac cttaatcatc atttactttc
     9661 ctctggattc aagctaatac cacttcaatc ccacatgttc attcatttct ttataggctg
     9721 tatcaattcg ttccttagtc gcttcatcta actggtcacg atgactgcca ccctctataa
     9781 aatcttccaa aatataagtt tggtaatgat acaagggata tccttctggt gaaaaggttc
     9841 cctttggtgt tcgattgacc caagtaggat gagctttagc tgttccgata gttgtttttc
     9901 catccttctt cttgatggtg acatccatga gaacaccacg ttcagtccac ttagcattct
     9961 cttcatctcc catagattca attcgttgat tggaaatgaa gttccccatt taatagacaa
    10021 tgagcttctt atctccatct ttttccaccg tttcagatgg ttcaacaacg tgaggatgcc
    10081 ctccaaagat aatatccgct ccccaatcga tcatcttgtg ataaagagct ttttgttctt
    10141 cagttggttc caatcgatac tcaacaccca tctgaggcat gataatggtg atatctgctt
    10201 ccttctctgc ccgttcaact tcagccttta tcttatcttc gtttaaatct gaaagataac
    10261 gattatagtc ttcctgagaa atatactgct caattccatt gaaaccatag gaataggcta
    10321 acaatgcaac cttgatagca ttcacttcct taatgaccag cggagcctga tcacgtggtt
    10381 cgtgcgtata aactccgatt ggagtgattc cagctttctc aataatatcg gccattgaaa
    10441 taactccctc aatttgcgaa tccaaaatat gattatgagc taaatccagc acatgataac
    10501 ctgcctcctt aatagcatcc ataacttcaa caggagcatt aaagagaaga taacccgcta
    10561 aataatgatc cttattaatg gttccttcaa aatcaccaat agctaaatct gcttgcttga
    10621 accaaggagt cacatactca aaattttcat gaaagtcata ggtaccgtct tcttttttag
    10681 ctgaaaagaa aagtccatcg tggtagagca aatccccgtg ggccataatt ctggcagttt
    10741 tttcctcttc ctactcctga gacttttgct tagtcccctc ttgagaaata gtatctcgtt
    10801 tttgactagt caagggattc cttggaagct ttcaaacaac aagaccaagc tcattgataa
    10861 accaactgct agcaagagta tcgccacaaa tcccttattg ctccacttgc gataactcct
    10921 aaaaagttta ccaagccctt cataaaacga aaagctaaac caccctgatt tcgattttgt
    10981 cttctttgta tcttcattct ccctactttc ttatgcaagc cttttctttt tattatatca
    11041 cagataagta tttctttcac aattgaattg aacttcctat ctattttcta taaatcctaa
    11101 atgccataat gctttcaatc cttgtcattt tgtgatatca tgtagaggta atgaaaggaa
    11161 ataaactaat ccacagtggc ttattccaag tataccactt gggctttggc agtagctaac
    11221 tgcactaaac ataatataag gagagaaaat gtctgcaata gaacgtatta caaaagctgc
    11281 tcacttaatt gatatgaacg atattatccg tgaagggaat cctactctac gcgcgattgc
    11341 tgaggaagtc actttccccc tatctgacca ggaaatcatc ctaggcgaaa agatgatgca
    11401 attccttaaa cattcccaag atcctgtcat ggctgaaaaa atgggactcc gcggtggtgt
    11461 tggactggct gctccccagt tagatatctc aaaacgcatt atcgctgttt tggtacctaa
    11521 tattgttgaa gaaggcgaaa ctccacagga agcctacgat ttggaagcca ttatgtacaa
    11581 tccaaaaatc gtctctcact ctgttcaaga tgctgctctt ggcgaaggag aaggttgcct
    11641 gtctgttgac cgtaacgtgc ctggctatgt tgttcgccat gcccgcgtta ctgttgacta
    11701 ctttgacaaa gatggagaaa aacaccgtat caaactcaaa ggctacaact ccattgttgt
    11761 tcagcatgaa attgaccaca ttaacggtat catgttttac gatcgcatca atgaaaaaga
    11821 cccatttgca gttaaagatg gtttactgat tcttgaataa agaaaatccc gttgcaagac
    11881 ggggttttgt gttataatag aggcatgaaa acaaatgata ttgtctatgg tgtccacgcc
    11941 gttaccgaag ccctccttgc aaatacagga aacaaactct acctccaaga agatctccga
    12001 ggtaagaatg ttgagaaagt caaggaacta gctacagaaa agaaggtgtc catttcttgg
    12061 acatcaaaaa aatctctctc tgagatgact gaaggtgctg ttcatcaagg ttttgttctg
    12121 cgagtatctg aatttgccta tagcgagcta gattacatcc ttgcaaaaac acgccaagaa
    12181 gaaaatccac ttctattgat tctagatggt ctaaccgatc cccataatct gggttctatc
    12241 ttgcgaacag ccgatgcgac caatgtttca ggtgtcatca ttcccaagca ccgtgctgtc
    12301 ggagtaactc ctgtcgttgc caaaacagcc acaggtgcta ttgaacacgt tccaattgcc
    12361 cgagtgacca acctcagtca aaccttagat aaacttaagg atgaaggttt ctggaccttt
    12421 ggaacggata tgaacggtac tccttgccac aagtggaata caaaagggaa aatcgccctc
    12481 atcattggaa atgaaggaaa aggtatctct agcaacatca aaaaacaagt cgatgagatg
    12541 attaccattc cgatgaatgg acatgttcaa agccttaatg ccagtgttgc tgcggccatt
    12601 ctcatgtacg aagttttccg aaatagacta taaaaaagtt tccagtcatc tgattggaaa
    12661 cttttttatg attaactatg ttctgtgata aacttgtagg cttcttgacc agcgatagct
    12721 ccatctccaa ctgctgttgt tacttggcga aggtctttca agcgaacatc tccaactgca
    12781 aagataccgt cgactgcagt cttcatgtga ctatctgtca caatccagcc tgcctgatct
    12841 tggatattca attctttaac aaaatcgcta agagggtcca aaccaacata gataaagaca
    12901 ccaccgaagg cttgttctgt cacttgacct gttttcacat tttcaaatac gactgattct
    12961 actcggtttt cacccttgat ttcccttact acagaatccc agataaagct gattttttca
    13021 ttcgcaaagg cgcgatcttg taaaaccttt tgggcacgaa gttggtcacg acggtgaaca
    13081 atggtaacag tcttagcaaa acgagtcaag aagagggctt cttcaacagc tgaatctcca
    13141 ccaccaacta ccaataaatc ttggtcacgg aagaaagcac catcacacac agcacagtaa
    13201 gaaacaccac gactgttcag ttcttcttct ccaggcactc ccaaaggacg gtgtttagaa
    13261 ccagttgcta cgataactgt acgtgtttca tatgtttggt catcagtcat cactttctta
    13321 aaatcaccat ggtcttcgac attttcaaca taaccataaa tgtgctcaac accaagattt
    13381 tcaagtggtt caaacatctt ttcagccaat tcaggtccac taatattagc gtatcctggg
    13441 taattttcga tatcagatgt attattcatc tgaccacctg gcagaccacc ttcaatcaaa
    13501 gctactttta gattgcttcg agcagcatac aaggccgcag tcatccctgc aggtccagca
    13561 ccgataataa tagtatcgta catatagatt ccttctttct tgttgtaact atctttattc
    13621 taactctttc ttgtcaatca cgcaaggatt atgccttgaa aacaagaatt aaactcataa
    13681 ccgcaaagga taatactggg acaaccaaga ctccaatcat aatcatatca tagagatggg
    13741 cttggcgagc cttggctgtc ttatcaactc ccgacatggc tctcagacca atccaaatcc
    13801 ctaaaaaaat cagaacaagg atggtggtca agatcaaact ctcgaaatat aaagaaaata
    13861 gttgcagtag catgatttct ctcatttcta tcttttttaa agagtaaact cagctagtcc
    13921 aactaactga gttttccttt atctattata tcaaatataa gtccgtttgt aactagcgaa
    13981 gaattctttt gtccgctctt ctttaggggt gtggataatc tcatccggag ttccagactc
    14041 gatgattttc cccttatcta agaagagaat cttatccgca acttgggcta caaaggacat
    14101 gtcatgactg accaaaatca tggtctgacc tgacttagca gcatctgcaa tagacttttc
    14161 tacttcaccg accaattctg ggtcaagggc tgaagttggt tcgtctaaga gcaaaacatc
    14221 tggtttcata gcaagcgcac gcgctagggc aacccgttgc ttctgtccac ctgataaatg
    14281 gcgaggataa tggttttcac ggtccgaaag cccaacctta gccaactctt ccttggcaat
    14341 cttagtcgct tcttggtcag ataatttctt gacaacaacc aagccttctt tcacattatc
    14401 aagtgctgtt cggcgttcaa ataaattaaa ctgttggaaa accatagaca acttacggcg
    14461 tagggcaagg atttcttctt gagtgatttt agaaaaatca actgaaaaac catcaatctg
    14521 aatagagcca ctgtcaggtg tttcaagata attgagactg cgaagaaagg ttgattttcc
    14581 agctcctgaa gaaccaatca aggctacaac ttcccctttt tgaatatcca agtccagatg
    14641 atccaagaca gtctgtcctg aaaaggattt gcttaaattc gaaatcttaa tcattaacga
    14701 aggtctcctt tcacatctgt ttgcactgta tcaggtgcag aaatagccat ttttctctcg
    14761 atgaaacgac cgaggctttc aattccgata ttgactaccc aataaacaag ggcaacggag
    14821 atgaagcgtt caaaatagcg ataatcagct ccacctagaa tctgagcttg ggcaaagact
    14881 tccacaacac ccgcactaaa agctagagat gttcccttgg tcaaaccgat gagggaatta
    14941 atcaaggttg gagtagctac caccgctgca ttaggaataa tcactcgtcg ataaacttgc
    15001 gctcgggtca tacccagact gcgtgccgcc tcaatctcac caggattaac tgagagaatg
    15061 gctgcacgaa tggtttcact agcataagct gcctcattaa aggcaaaggc gacaatcgca
    15121 aaagctgcag ctggaatcgc attgatattg agaccagttc cccattgctg attgagggct
    15181 ttcaaagcca aagggattcc gtagtaggtc aacatgagtt gcaccaaaat cggtgtccct
    15241 tttaagaaac taacaaagaa ggcctgcaag ggatataaaa tcttgacacg attgatcttc
    15301 acaatggcaa aaagaagcgc caaaaccaag ccaaaaaggg caccaccaat tgtcaacata
    15361 attgttgttg gaagttgttg gacaattcta gggattccat caaagaccga acgtaggcta
    15421 aacagcttgc catccggaat caattgcatc aagttttggt accaatctga tgctaaaatc
    15481 gttgtaacat tcataaaaac atcctcttct gataatgatt cattctacca tgcttctgcc
    15541 gtcaatgaaa ttatttgcta cggtcagata cagactttgt ctacctacta gtttatcata
    15601 ctttgaaaca gggaagttat atattttatc tatcaaagag atagataaaa actatttcag
    15661 tcccagttct tcataagatt ttcgataacc gatttgctta acggttccat tttctactaa
    15721 aatgggccgt tttaacaaca taccgtcact tgctagcaac tcagccgctt cttggtttga
    15781 caaacttcct accttatctt ttagccctaa ttcacggtat ttgataccac tggtgttgaa
    15841 aaattgcttc aattcaaatc ctgaggtttc tagccaattc aaaatgactt cttggctagg
    15901 tgtttcttcc acgatatgga cggctttata gtccacacct aattgattta attcttgttt
    15961 tgctttttta caagttgaac atttgggata ttcgataaat tctaacatgt gcttctcctt
    16021 ctattgtttc tatctttaaa atctactcct tcatgctcca agagccaagc tttcttttcc
    16081 actcctgcag cataacctgt cagacgcttg cctgctccca acacacgatg acaaggtact
    16141 aggatagacc aaggattgcg tcccactgct ccaccaattg cttgagcaga agccacttgc
    16201 aggtcttgag caatttgtcc ataggtcact gtctgaccat aaggaatgcc ctgtaaatag
    16261 tcccaaactc tcttttcaaa attcgttccg attggcgcca agagcaagtt ggataaatcc
    16321 tgaggcttgc ctttaaagta atcatctaag caagcaataa ctgggtctaa aataggatga
    16381 ctaacaactt cttctatcgt ttcatctcct agtcccctct caaaatgctt ctgctcctga
    16441 acccaaattc catacaaata atggtcatca gctacaagtg atagaatacc aattggtgag
    16501 gagtagagga tttttacata cttcttttgc attatttctt taatttttga taggccaagc
    16561 gttcgccatc tactggcacc ttaccaactt gtttaaaacc aagtttttca aaaatatgtt
    16621 gcataacctt gttttcagca tgcgtatctg agcgaaaatc aagataatca aaaccttcaa
    16681 tcaagccctc taagaaggtt tgagcaactc cttttccctg cacatctgct gccacagcaa
    16741 tacggtgaaa gactagatac tctgactctc cagcttgcca gtttccctca taaatagctt
    16801 cataggcctc ctctggactc ttggtcacag cagcataggc tagcagttct ccctcttcca
    16861 aggctacgta ggcttgccct gagatgatat catcgataat aacatctgca tttggatagc
    16921 cattttgcca ctggtcacta ccagcatctg ctaaacattt tttggcatcc tccatcacct
    16981 gcatgatggc atctacttca tttggaaaag ctaaacgaat ttccatcttt tttcctcatt
    17041 tctgactagt ttctcccatc atagcataat ttaagtattt ctacaagcag ttaaaacttg
    17101 actttgtgtt tttgttattt tataatctag ttatcaaaac tatataaaaa ggagttgaaa
    17161 atgaaaacta ccttttccta cccaaaatgg gcagaaattc caaacattga cctctatctg
    17221 gaccaggttt tgctctatgt caatcaggtc tgcgccccta tctctcctaa taaagacaag
    17281 ggcctaacag catctatggt caacaattat gtgaaaaatg gttacctgac aaagcctgac
    17341 aaaaaaaaat accaacgcca acagattgcc cgtttgattg ctatcacaac cctcaagtct
    17401 gtattttcta ttcaagaaat agcccagaca cttaatactc tacaaactca agcaagttca
    17461 gaccaactct acgatgcttt tgtggactac atgaaccaag gaattgaccc agctaaccct
    17521 attatccaaa ccagctgcca aaccgtcaaa ctctatcatc aaactctaga cttaatcgat
    17581 catactcaag aggaggtaat ccaatgaaca ctagtcttaa actcagcaaa caactcagtt
    17641 ttggagagga gattgctaat agcgtgaccc atgctgtggg tgcagtcatc atgcttatct
    17701 tgctgcctat ttcatccatc tatagttatg aagcacacgg atttttatcc tctatcggcg
    17761 tttccatttt cgtcatcagt ctctttctca tgttcctatc atccaccatt tatcactcta
    17821 tggcctatgg ttcgacccac aaatatgttt tgcgaatcat tgaccattct atgatttacg
    17881 ttgccattgc cggctcatac acgcccgttg tcttgacctt gatgaataac tggtttggct
    17941 atctgattat tgtcatccaa tggggaacga ccatctttgg tattctctat aaaatctttg
    18001 ctaaaaaggt caatgagaaa tttagccttg ctctttacct gattatgggc tggttggttc
    18061 tggctatcat tcctgccatt atcagtcaaa cgacacccgt tttctggagt ctcatggtaa
    18121 ctggcggact ctgttataca gttggagctg gattttatgc caagaaaaaa ccttatttcc
    18181 acatgatttg gcatctcttt atcctagctg cgtccgcact ccaatacatc gctattgttt
    18241 attacatgta aaaaagttga gaaattcaat ctcaactttt ttctttacac atattgataa
    18301 agtactggtg caagcgcaca tcatcagtca attctggatg aaaagaactt accaacatat
    18361 ttttttcttg ggctgcaaca atttgattgt tcactattgc taaaatttct acaccctcac
    18421 caacactact gataatcgga ccacggataa aggtcattgg aatcttgcca actcccttac
    18481 attctgcttc cgtgtagaaa cttcctaatt ggcgcccata agcattacgc tcgaccacca
    18541 tatccatagt tcctagatga ctctctttct gagaagtgat ttccttagcc agcaaaatta
    18601 agcccgcaca ggtcccaaac actggtaagc cagatagaat ggcttctcgt atgggaagta
    18661 gcatgttctg gtcacgtaag agcttgccca tggttgtaga ctcaccacca ggcaaaatca
    18721 aacccgacaa gtcactctga tcttgctgaa aatcatctag atttctgagt tctacactct
    18781 cgacacctaa ttgatctagc acttttgcat gttctgcaaa ggccccttgc aaggccaata
    18841 ttccgatttt catctatttt cctcgttcag ccatgagaat ttggatttca ttttcattaa
    18901 taccaaccat ggcttctcct aaatcttcag agatttgagc taggatttga ggattacgga
    18961 agttagtcac agccttaaca atggcattcg ctcgtttaac aggatctcct gacttgaaaa
    19021 tacctgaacc gacaaagacc ccctctgccc ctaattgcat cattaacgca gcatctgctg
    19081 gcgttgcaac acctccagca gcgaaattta caactggcaa ttttccatgt tcatgaacat
    19141 attggaccaa ttctacaggg acttgcaaat ccttggcagc aacataaagc tcgtcctcac
    19201 gtaagttttg aatgcggcga atttcctgat tcatcatacg catatgacga acagcttgga
    19261 ctatatcccc tgtccctggt tctcctttag tacgaatcat ggaagcacct tcagcgatac
    19321 gacgcaaggc ttcacccaaa tccttagcac cacagacaaa aggaacttgg aattctttct
    19381 tgtccacatg gaaacggtca tcagctggag atagaacttc actctcgtcg atataatcaa
    19441 tttcaatagc ctctaaaatc tgagcttcaa caaaatgccc gattctgacc ttagccatta
    19501 ctggaatact aaccgcttct tggatttcct taatcatctt tgggtcgctc atgcgggaaa
    19561 ctcctccagc tgcacgaata tcagccggaa ttcgttccaa ggccatcaca gctgccgcac
    19621 cagcagcttc tgcgatacga gcctgttcag gattctgcac atccataata acaccaccct
    19681 tgagcatctg tgccaagttt ttatttagtt cataacgatt ttcagtcatt tgttttatcc
    19741 tcatcatttg tattggtagc taccttttca ttttaagtca gaacagaatg aagcacaaga
    19801 taaaaaaact ataattgtat ggggacagat tagctaaaaa ctatctgacc ttaacttaag
    19861 gccagatagc tcattcattt ttatttttca gccgtaaggg cagccattgt gatgtagttg
    19921 tatggtttgt tgaagtgtgg caagaagaag aggtctgtca atgccaattt atcaattgtc
    19981 acatgctctt ggatagcaag tgagaacatg tggattccca tgctaattgc aatatcatgt
    20041 gaaaccattt gggcaccaag aatttcacgg ctatctttgt caaagacaat cttaattgct
    20101 acttcatggt tgtcatgttt catgaattct ggtttttgaa gatcgttaaa gcctgtttca
    20161 gttgcgttgt aaccagcagc tttcgctttt tcaagagtca aaccagttga aaccatgtga
    20221 agaccgtaga ttgagatacc atttgaacct tgaacaccga ttccttccaa ttcatgtcca
    20281 caagcgttgt aggcaccaac gataccagtg cgaacagcat ttgaagcaag agcgatatag
    20341 cttgtatctt tacgagcatt gtcataaaca gtcgcacagt caccaacagc gtaaacgcct
    20401 gggatagatg tttcttgttt cttgtctaca aggaaggcac cgttgcggaa gagttcgatc
    20461 ttaccatctg caagggctgt gtttggacgg aaaccaactg caaggataac catatccacg
    20521 tcaaagcttt ctttgtcagt aatcaagcgt tcaactttac cgtcaccttc gattgcttta
    20581 acagtttgac ctagagccaa gcggatgttg tgatcttcca agttcttcgc catcatttgt
    20641 gtgaagtctt tgtcatagta accgttcaag acagtatcaa cgatatcaac aaggacaact
    20701 tcttttccaa gacgttcaaa ggcttcagca agttcaacac cgatgtaacc accaccaaca
    20761 acggcgatac ggtcgaggtg ttggctcttg tcagaaagtt tattgataac ttcttcagca
    20821 ttttggtaca atttcacgaa ttgtacgttt tcaagagttg ctttaaattc gcggtttcct
    20881 ttaacaattt caacaccttc gattggtggt aagattggtg tagaacctgt agcgaaaatc
    20941 aatttttcgt atgattcttt gtgctctttt ccttcaactt ccgctgtaac tactttgtta
    21001 tcatagtcga ttgaaagaac aggtgagttc atgtaaactt tagcaccttt agcttccaat
    21061 ttttctttat cagaatagaa caagccttca gcaccgtcaa tttgttcacc aatccaaaga
    21121 gccattccac atcctaggaa agagatgtta gagttttggt caaatacaac aatttcgttc
    21181 tcatttccaa aattatccaa catggtattg atacatgctg taccagcgtg gttagcaccg
    21241 actacaacga ttttactcat aaaaatttcc tgccttcatt ctaaatttac cttactagta
    21301 taccatttac cgttagcgtt tacaaggggg gtactattat ttcagcattt tttatcaaaa
    21361 ataattcccc atttatcctg ttttcaagcc tcatgaattt tatgagcata tttcttgact
    21421 ttttccaaat tttgtttgtg gaaattctaa ctttatggta ttataataac atgaaaataa
    21481 aatgtaaggg cttcaattta gatgattatt tgatattaca acttattttt tataagagaa
    21541 aggagttggt agcttgactc ttcgttcaca ttctgaacgg ctaatgggga ctactatcac
    21601 tatttcatta gtggatgagc aagccgatat ctttctccaa aaatcctttg acttgctcaa
    21661 agagcttgaa taccgcttca acgccaatag tcaagaatct gagttgatgg aaatcaatta
    21721 tcaagcagga atatcccccg tcacggttca tccagacctg tttgagctga tttcacttgg
    21781 gttagagcat agcctagcgc tctctagcca cctcaatatc agcattggtc ccttaattca
    21841 aacctggcgt atcggttttt cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt
    21901 gctgcctcta atcaatcctc atggtatcga gttagattct tctacttcta ctgtgttttt
    21961 aaaacagaaa ggaatgaaga tcgatctagg ttgtttagcc aaaggataca gtgcggataa
    22021 ggttgcccaa tttcttagga aagagggggt gacttctgcc ttgatcaatc tgggagggaa
    22081 tatcctgacc attggaaaaa atcaggcaag aggggataac ccatggcaaa tcgggattca
    22141 agacccagcc aatcctaggg gaaatcattt aatgaccatc cctgttgtca ataaatctgt
    22201 cgtgacttca ggcatttatg aacgtcacct gaccgtcgat ggacaagatt accatcacat
    22261 ttttgacagt caaacaggat atcctgttga aacggaacta gcgagtctaa caatcatctc
    22321 tgataaatca gtcgatggcg aaatctggac gactcgactc tttggagaaa gacctgcttc
    22381 tatcctctgg caagtcgaaa gtttggaggg catcgaagtc atcctcatcg ataaagaagg
    22441 ccacctaagc tgttcttcag gaattcctac tctataaaga caactgtttc aatggaattt
    22501 taaaattgta ttatgtaaaa agagaaagga aatctcatgt taaaacttat tgctattgtt
    22561 ggaacaaatt caaaacgttc tacaaaccgt caattgcttc aatacatgca aaaacacttt
    22621 gctgacaaag ctgaaattga gcttgttgaa atcaaggcca ttcctgtctt caacaaacca
    22681 gctgacaagc aagtacctgc tgaaatattg gaaattgctg ctaaaatcga agaggcagat
    22741 ggcgttatta tcggtactcc tgagtatgat cactctattc cagctgtttt gatgagcgct
    22801 cttgcttggt tgtcttatgg tatttaccca cttttgaaca aaccaatcat gattacaggt
    22861 gcttcttacg gtacgcttgg ttcatctcgt gcccaattgc aacttcgtca aatcttgaat
    22921 gctcctgaaa tcaaggcaaa tgttcttcca gatgaattct tgctctcaca ctctcttcaa
    22981 gcatttaacc caagtggcga cttggttgac cttgatgtta tcaagaaatt ggatgccatc
    23041 tttgatgact tccgtatctt tgtaaaaatc acagaaaaat tacgtaatgc acaagaatta
    23101 cttcgcaaag atgctgaaga ctttgactgg gaaaatttgt aagataggag accaaaaaga
    23161 atgaaatttg ttggacttgt tggatcaaac tacgatcaat catataaccg taagctcttg
    23221 gaatttatcc gtcgctactt caaactcaaa tttgaattag aagttcttga aattgacgaa
    23281 gttccaatgt ttaaccaaga tgaaaaatgg gatgaaagtt tccaattacg ttatttatat
    23341 aacaaaatta ctcgtgcaga tggtgttatc attgctactc ctgagcataa ccacactatc
    23401 tcagcttcac tcaaatctgt acttgaatgg ctttcatacg aagttcatcc atttgaaaac
    23461 aagcctgtta tgattgtggg tgcatcatac tatgaccaag gaacatcacg tgctcaagtt
    23521 caccttcgta aaatccttga tgctccaggt gttaatgcct acacgcttcc aggtaacgaa
    23581 ttccttcttg gtaaagctaa ggaagctttt gataacaacg gaaatatcac caacgaaggc
    23641 actgttaaat tccttgaaac ttgcttagat aactttgtta aatacgtagg agtcgtttcg
    23701 aaattgaaaa aaccaaaacc aatcgaatca gaagacttgg attgtggaaa accaatcgct
    23761 acaaccatca cagaagttga ccctgacgat ccagaatggg tagaaaaagt tgcagcaatc
    23821 actggtgctg tttctggtga tacctatgtc aaattggacc acggtatcct aacagttaac
    23881 caaattgata tgttcttgaa agctatgcca tttgaattga catacgctga cgacaacaac
    23941 caattcctct actacaacaa cgctcaccaa gatccagaca ctatgttcgc taaacgtgta
    24001 ccacctcaat caggtagccg tatgtcgact gttcatggtt ctcttccacc agcacgtatg
    24061 aagaacgtag agtgggttat cggaacactt cgcaacggaa accaagaata cgtccgtacg
    24121 atcgttccag gttctcctgc aggtgttatc aacactcaca actaccaagc aatgtactat
    24181 cctgatggat catacgctgg tatcaatgaa atcgtcttta acttccaacc atggcttgac
    24241 tggtacctaa aagagactgg tcaacgtttg gtgggtggta gcggaccatt tgctcctgct
    24301 gccggaggtc atggaaacgc cgatgctact tctggcgctt ctgattcagg ggatgctgga
    24361 ggccacggtg gtgacgcaga tgctacagcc ggtgcaagtt actaatgata gtttttagga
    24421 accattatgg ttcctttttt agcgaaaaaa gactagcaaa cacaaactgc tagtctcttt
    24481 gttatcgttt catctatctt tgttaaaaga aagaatacat attatgaatt tgggtcatca
    24541 agactacggc catgtaatcc tttttcacgt tgtacttggc gtagtttttc tggtgtaaca
    24601 tcgtttcctt tttcgtccac aattttgatt ccttcaatgt ggtgacgaac agcgcggcga
    24661 taaccttcga tgtactcctc acgtagtttg gcttgttcca ctttttcttc tggtgttaag
    24721 ccttctgttt ttttcttttt agcaagctca ttgatacgag caattttttt cggatccatt
    24781 tcttctcctc tgtaataaga taaagtccgt ttatcaaatt ttatttagtg ttaatttggt
    24841 taaaacaagc aaacttagct gctttcttgg ttagttgtga caagattgcc aaacgatttt
    24901 gacggacagc ctgatcttca gccattacca tagtattttc aaagaaagca tcaatgactg
    24961 ggctaagcgc aaagagttgt ttcaattgct gacttgcagg tcctgataaa acgagtgttt
    25021 ctactgcttc tgccaaagct ttttcttggt cattctcaaa tagtgctgaa tcaactgtag
    25081 caaccccttc tgccttctca gccaggttaa aggcacgaga aagtgattca acagatggtt
    25141 taaaatcttc ttccttgctt acttctacga gagcacttgc tgcttccaac atatctgcca
    25201 caacaaagtt tgaacctgca agaactgctt ccttgatatc ttttggagta gagcccatca
    25261 tcttatcaac acgagccttg ataaagtcca taacctctgc tttattttca taagtcaaac
    25321 tgtcaaattt caatgcataa aggctatcaa tcagctcatc catagcaatg tgccaaccaa
    25381 aggcatccaa gatacgaacc acaccttgag ttgcacgacg aagggcataa gggtcattag
    25441 aacctgatgg aatcaatcct actgagaaga aactcaaaat cgtatccaat ttgtctgcaa
    25501 tggctagaac tgcaccgacc ttgctctctg gaagttctcc ttcagctgat gtaggcatgt
    25561 agtgttcacg aatagcagct gccaccgctg gagtttcacc agcaagaagg gtgtattttt
    25621 cacccataat tccttggagt tcgtcaaatt caccaaccat acctgtcaac aagtcaaact
    25681 tgtaaatggc tgctgcacga gcaaggtcaa ctgtttcatc cactgacaaa ccagcttttt
    25741 ctgccaaaag tacagtgatt tgacccgtac gaatcatgtg ttcacgaagg gaaccaatct
    25801 tctcatggaa ggtgacattg tttaattttt caacaagatc tgaaatcacc aatttttggt
    25861 cttcacgcca gaagaattct ccgtcttcca agcgggctac caagactttt tcatttcctt
    25921 tgatgacatt tttcaaacgc tctgcgtttc cgttacgaac agaaatgaag tttggcaaga
    25981 gttttccatc ttgatcacga acaacaaagt aacgctggtg ttccttcata gaagtcacca
    26041 agacttcttc tggaacttca aggtatttag catcaaaact tcccatgaag gcagttgggt
    26101 attcaaccaa attcaagact tcattcagca aatccgcatc aatttcgata cgtacaccat
    26161 gttttgcctc aatttccttg atttggtcaa caatcatttg ctcacgttca catggatctg
    26221 cgattacaaa ctgcttacga aggtcttctt catagctcaa tgctgactga attttggttt
    26281 ctttccccaa gaaacgatgg ccacggctca cacgacttcc cttgatatca aggaaatcca
    26341 agtcaaactc ttgctcatcc aagagaacag ttaaagtgtg aacagggcgg atgtattcaa
    26401 agctatttcc agcccagtgc atgctgacag ggaaagtcaa tgacttcaag acatctacaa
    26461 caccaggaac aatggcttca actgattggc caacttcttc cttagtgaca tagacatatt
    26521 cttcaccctt aatttcacgg aattcgatat cttcaacagt caaacctttc ccacggacaa
    26581 atccttgagc tgctttggtg aagtttccat cactatccaa ggcaattttc tttgctggtc
    26641 ccttgaaatc ttctgtcaaa tcagactgtt tgtctgataa accagtcaca cgaacagcca
    26701 aacgacgtgg tgttgagaag gtttgaatgg cttcaaaaga caggcggttt tccttgagga
    26761 aggctgccat tttttcgcct agttgttttt cacttggtgt gacaacatag gctggtaatt
    26821 cttcaagacc gagttctact aataagtttt ttgtcatgtt ttttctccga aaagtatctt
    26881 tttattttcc agtttgcctt atgtgattgg cacgcaagca accaacttcg ttgtttcatt
    26941 gctaaaattg gagccaaaag tctccaattt tgcctagtat ccttagtttc actaaggata
    27001 ccttcatcac tgcggcaact ggctcagggc tcactctgtt cgcccatttt cgtaatttgt
    27061 cactctcttt attctgcgtc ttctgctagg agtttagctc ttgtttcttc atccaaaagt
    27121 gggtagccta ggcgtttgcg ttctgcgaca aaggttttgg ctacgacacg ggccaagtta
    27181 cggatacgag cgatatagcc tgcacgctct gttacagata cggcaccacg cgcgtcaagc
    27241 agattaaagg tatgtgaaca tttgagaaca tagtcatagg cagggtgtac caagccttct
    27301 tctaatgcac gaccagcttc tttttcaaac ttatcaaaat tttcaagcaa catttcttgg
    27361 tccgaaattt caaatgaata ttttgagtgc tcatactcag gctggataaa gatttctccg
    27421 tattttacac catcagccca ctcgatatca tagacagagt ctacttcttg aatgtaagaa
    27481 gccaagcgct ccaaaccata ggtaacttcc gcagtcacag ggccagttgc caatccaccg
    27541 acttgttgga aataagtgaa ctgagtgatt tccattccgt caagccaaac ttcccaacca
    27601 agaccagctg aaccagttga tgggttttcc cagttgtcct caacaaaacg aatatcgtgc
    27661 tccaaaggat tgattcccaa tttttccaaa gactcaaggt aaagttcttg gatatttgat
    27721 ggagaaggct tcatgaccac ctggaattgg tggtgttggt agagacggtt agggttttcc
    27781 ccataacgac cgtcagcagg acgacgtgat ggctctacat aagctgcatt ccatggctca
    27841 ggtccgatag cacgaaggaa agtgtaagga ctcattgttc ccgcaccttt ttcattatca
    27901 taagcctgca taagcataca accttggtca ttccaaaatt gttgcaaagt aaggatgatt
    27961 tcctggaaag tcaatttctt agacattgtt tactcctttt tatataaatt acttgcgaca
    28021 tgaggctgcc tcgtcgatca tacgaggcaa gacgagttag tactgcgtct agctcaggca
    28081 ctctagtgct gagcgtgggg cagtccgact gtaaggaggt ttctgccact gatgcagtga
    28141 aatgttaatt tctcagacat tgaatactcc ttaataaaaa ataatttctt gcgacacgag
    28201 tctgcctcgt cgattatacg aggcaagacg agttagtact gcgtctagct cagcacccta
    28261 gtgctgagcg tggagcagtc cgactgtaag gaggtttctg ccactaacgc agtgaaatgt
    28321 caatttctta gacattgttt actcctttag tttttatatt tctttttcaa ttaatttctg
    28381 ctgaacaaac caatctaaca agggaaaagt tttttctgta tttgcccata aatgataaga
    28441 atctaagacc gcttgtacac tacccaaatt ttctaccaac ttatctactg tcaaaaagct
    28501 gcgccagtat tcataaaaaa tacttgcata gttcttatca taagtcgaag aaccaaaatc
    28561 attcaatgaa tgccaactat acttcttctg aaaaagttct acgagagatt gattacaaat
    28621 tttttccgct tgaaattcct cttctgtcaa gaaatacttg cgactaatat attcaaccat
    28681 cccctcttcg aaccagatat aagagtcata accatcaaaa tcatctaaaa aatgctccga
    28741 ccaatgagct aactcatgtc ctacaatctg taagaggaaa ttttcagata aagaatgata
    28801 gtgactttct attgcttgag tttgctgaga acactcgtag tccatcaatt gatacaaata
    28861 caactctttc caaacagcta aatcaggcgc cataaccatt cgtctattat ttgtataggc
    28921 tggaacagcg ctttccctaa taatctgtgt agcagcatta aaatctgacc aaataacggc
    28981 ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa gattgataat ctttcaactt
    29041 ttcagtattt cttactacaa aatcacgaaa tgtagctagt tgactatcgt cttttacaag
    29101 ataaaggttg tccacggctc tcctttcttt cacacaatag actgaataag caaaagaacc
    29161 gcgtccgaca atcctaggtt gatttaacct aggggcgtca gaaacgcggt tccaccctaa
    29221 tttattactt cattgttttt gaaaatacta cagaaagcgc cagctcatta ttttgcccta
    29281 cttggctccc actatcccaa gctcgcttga agaacgccat aagactttct ttcctgctga
    29341 ctattatatc aaaaattaga ataatgtaca attcttttta tgattttcta gaaatccaca
    29401 tcatcaactc gtggagcacc cgattgaaca gcaatcgttt ttaaggtttc tctctcctca
    29461 tgactcagtt caattccaaa gcaatcaaga ttagcttgaa tacgagaggt tgtgacagat
    29521 tttggaagtg gtaaaaatcc ttctgccaag ctccaggcca aggctatctg agcaatcgat
    29581 tttccgtgat ttgctgcgat ttcttgcact tgcttgctat caaatagttc tccctgacca
    29641 aaaggccccc aagcttccaa taaaattccc ttttcacgac agtaagctac gacttgatct
    29701 tgatacacac ctggcgccaa gcgaacttga ttgaccgcag gaacgatagt tgcagtttca
    29761 agcaaggcat ccaaatgatg gggaagaaaa ttgctaacgc cgatagcacg gattttccct
    29821 tcttgataga ggtcttccat cgctctccaa acttctgcat ttcggatttt ccattggtca
    29881 ttttctctga gcggttttgg atttggccaa tgaatcaaat acagatccaa ataatccaag
    29941 cccagtttct ctaaagactc ttcaaaagcc tgacgagctt gctcataggt ttgttggcta
    30001 ttccacagct tggtagttac gaacatttct tcacgtggaa ctccgctatc tttgattgct
    30061 tgaccaacac tttcttcatt ctgataaatc gccgccgtat caatatgacg ataaccagcc
    30121 ttcaaggctt ctaacactgc acgataggct tcttctccat ccttagcctt aaaagttcca
    30181 aatcccaata ctggaatttc tactccatta tttaattgat aggtattcat atgcttctcc
    30241 ttctatttta ttcatcaatt atagcataaa acatttttta agtagtacta tcttctgtaa
    30301 aaaataagtc tgtcaaatat ctaacagacc tattttttct tgcttattca tcacgactat
    30361 agtacagctc atgagctttt aggcgagtat tgagcatctc tggtatggtc acaaaggtat
    30421 aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc attgactgtc ggactgtgaa
    30481 tgtcatgcat caaaacgata gagccgttag ctacttgatg ctgaatttct gtcaaaatag
    30541 atgcttcatt tttactcttc cagtccagac tatccacatc ccacatgata aagctcaaat
    30601 ccaagctatt gcgaatatca tctgtaatag caccataagg tggacgcatg agtttagaac
    30661 tagaacccag cactttagtt agcacatcct cagtatcagt aatctgcttt ttagcttcat
    30721 caagagagag ttgcgagaga atcggatggc tccaactatg gtttccaaca acatgacctt
    30781 cagattttat cctcttcacc aagtcctcat tcccagaaac atttttccca agcacaaaga
    30841 aagtcgcttt aatatcatat ttagctaggg tctctaatac ctgcggggtc gttgctggat
    30901 ttggaccatc atcaaaggtt agagcgacaa ctttttgata tttcttatca aagtaagatt
    30961 ggtacaaggc cgcatctttt tcgagtaagt acgaagattg gataacatca aagaaagcag
    31021 atactggcaa ggctatctct tctaaatttt caaccacagg acttggataa aggataatct
    31081 gactatcctt gtaatcaaaa ttccatgcag acaagtcttg gtcagagaag ttttttacaa
    31141 tctgctcact ctggtcttgc tctatttttt tatcctctat gaaggaggtc aactctttta
    31201 tcagctgttc cttagcctta ctagcatctg aaaacagttg gtcaagtgta aaaggttgcc
    31261 catcttctgt taagtgaacc tttcctagac tggtcttttc agtctcttca accttaaaag
    31321 caactaaatc atagatttgt ttggtcacat tacgattaac gactcccttt aaacctgact
    31381 cttcttgctc tgtatagtag aaaacaagat tgtccttact ttctagcttg tccttaacat
    31441 cttgatttat caactcccta acagaggaaa tcactttctc cccttggaga ggataatagg
    31501 caatcacttc ggcttgcccc tgacgaaaat gctccttctg atttccctca ctcaattgat
    31561 catctttctc ttttttgagc gattcaatct tttgctcaaa acttttttgc tggtagatct
    31621 taaaagcaat aaatccgcct aataggcaaa tagaaattgc taaaatacca atcaaagcca
    31681 ataatacatg tctcgttttc ccgtgtctgc cacgtcctag tctactttta ttcatattta
    31741 tatcataaca aatttgagca ataatttcaa tgatacaatt tggcaatcca caattcctct
    31801 agcaagccaa agcatcttac atcaactcca acatccgtat ctgtagagat tatgtagttt
    31861 tctatctatg gaatttctag tagattgaag ctagaatagt agacctatac ttctaaaaca
    31921 ttgttagaaa tcgatttgat tgtcctgatc gatttgtcct gttcttattt cattttacta
    31981 taaaactatg agaagctagg tcatctgaga agtaattact atcgacaatt gcgatagcgt
    32041 atactggtgc aatttgtttg tagctctggt gggtatcacc ttcacgttgg cgaatttttt
    32101 ctaggttttg attaacctga ctgcacagat aagcccatag gcgattgatg aaaaaattct
    32161 gatgatgaac ctgaatttcg atgataactt gggttccatt atctaactcc gccaagacat
    32221 ctatactagt atagaaatcc tgcgctgagt agggcatgga aggcaagacg tgaatgttac
    32281 ttccctccaa aatcgtcaca ttttttgctg gcaagtccag catatcgcgg ataaattgac
    32341 aaagcattag ttgggctgat acccggatgt ctgagaatcc tccttttcct ccttctatta
    32401 tagcacattt ttaaatctag gtttgctaga ttctatgctt ctatctattt attcggaaaa
    32461 gaaagctttt cttcagaaga aagctaatag cttatttgaa attttctcct ctctgttgga
    32521 tagtcccgtc tatctatgtt ataatgaaag aaggatttaa aatcggaaaa ggagtattta
    32581 tgctaaaatt aggtatcatc ggaactggcg ctatcagcca tcatttcata gaagcagccc
    32641 ataccagtgg agaataccaa ctggtcgcaa tctattctag aaaactagaa actgcagcaa
    32701 cctttgcttc tcgctatcaa aatatccaac tattcgatca attagaagtc ttcttcaaat
    32761 cttcttttga tttagtctat atcgccagtc caaactcctt acattttgct caggcaaaag
    32821 ctgccttgtc tgctggtaaa catgttattc tcgaaaagcc agctgtcact caaccacaag
    32881 aatggtttga tttgattcaa acagctaaaa aaaataactg ttttatcttt gaagcagctc
    32941 gtaattacca cgagaaagcc tttactacta tcaaaaactt tttagcagat aagcaagtgt
    33001 taggagcaga tttcaactat gccaaatact cttccaagat gcctgacttg ttgactggac
    33061 aaacaccaaa tgtcttttca gaccgctttg ctggtggagc cctcatggat ttggggattt
    33121 atcccctcta tgctgctgtt cgtctttttg gaaaagccaa tgacgcgact taccatgctc
    33181 aacagcttga caatagcatt gacctaaatg gagatggtat cctcttctac ccagactatc
    33241 aagttcacat caaggctgga aaaaacatca cttccaatct tccttgcgag atttatacaa
    33301 cagatggaac cttgactctc aacacgattg agcatattcg ctcagctatt tttaccgacc
    33361 accaaggaaa tcaagtccag cttcctatcc aacaggctcc tcatacgatg actgaggaag
    33421 tcgctgcatt tgcacacatg atccagcaac cagatctgaa tctctaccaa acttggctgt
    33481 atgatgcagg ctctgttcat gagctactat ataccatgcg ccagactgct ggcattagat
    33541 ttgaggcaga aaaatgaaaa ccaaactacc gactgaatgg caagaactga gtgaccaact
    33601 cggtttccaa gaattcaccc ccattcaaac tcaactattt gagccccttc ttgctggaga
    33661 aaacctccta ggagtgagcc aaaccggaac tggtaagacc ctagcgtatc tcctaccaag
    33721 tcttctcaga ctacaaaaga aaaaagccca acaactcttg attctagcac caaatacgga
    33781 acttgctgga cagatttttg atgtatgtaa aacgtgggca gaagctatcg gattgactgc
    33841 tcaactcttc ctttcaggtt caagtcagaa acgacaaatt gaacgtctta aaaaggggcc
    33901 agaaattctg attggaactc ctggccgtat ctttgaactc attaaactta aaaaaatcaa
    33961 gatgatgaat gtggaaacca tcatcctgga tgaatttgac caattactag atgattctca
    34021 gattcacttt gtagaaaaaa tcactcacta cgcacctcgt gaccaccaac tggtctacat
    34081 gagtgccacg accaagtttg accaagaaaa gattgtgccg aatacacgca ctattgatct
    34141 ctctgatcaa aaattggaca atatccagca tttctacatg caggtagacc aacgtcatcg
    34201 agtggatatg ctacgaaaac tggctcatgt agaggatttc cgtggtctag tcttcttcaa
    34261 tagcctgtca gaccttggga atgccgagga aaaactacag tatcgtgata tattggctgt
    34321 ttccctcgct agtgatgtta atgttaaatt tagaaaaatc atcttagaaa agtttaaaga
    34381 taaccaacta accctgcttc ttgcaactga ccttttggct cgtggaattg atatcgatag
    34441 cctagaatgt gtcgtaaact ttgatattcc tagagatagc gaaacctaca cacaccgtgc
    34501 tggccgtact ggtcgtatgg gcaaggaagg ttatgttatc actctcgtca ctcatccaga
    34561 agaaatcaaa aaacttaaaa agtttgcaag tatccgagaa attgtcctaa aaaaccaaga
    34621 actctatatc aaataaagcc ccattgctct atacacatcc agtgtatgaa gcttttttat
    34681 aagcaattca attttatact catctgcttt caaaaagcat tctagtccat ttccgattaa
    34741 caatggactt tatcacctcc ttctccagtc cttgtatgac atcttgaagt tgattcatga
    34801 catcttccaa agttcgaaag gctttattct taaatccacg tttatgaatc tctttcaaca
    34861 cttgttcaa
//
LOCUS       DAVHBD010000021        34678 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000021 DAVHBD010000000
VERSION     DAVHBD010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.021"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..560)
                     /locus_tag="VVK04_001077"
     CDS             complement(<1..560)
                     /locus_tag="VVK04_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU3989742.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGIL"
     gene            630..1076
                     /locus_tag="VVK04_001078"
     CDS             630..1076
                     /locus_tag="VVK04_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989743.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            complement(1304..2482)
                     /locus_tag="VVK04_001079"
     CDS             complement(1304..2482)
                     /locus_tag="VVK04_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU3989744.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            2762..4024
                     /locus_tag="VVK04_001080"
     CDS             2762..4024
                     /locus_tag="VVK04_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU3989745.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYAILDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            4027..4923
                     /locus_tag="VVK04_001081"
     CDS             4027..4923
                     /locus_tag="VVK04_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU3989746.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            4938..5255
                     /locus_tag="VVK04_001082"
     CDS             4938..5255
                     /locus_tag="VVK04_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU3989747.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            5272..5589
                     /locus_tag="VVK04_001083"
     CDS             5272..5589
                     /locus_tag="VVK04_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU3989748.1"
                     /translation="MNESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            5599..6954
                     /locus_tag="VVK04_001084"
     CDS             5599..6954
                     /locus_tag="VVK04_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU3989749.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSSVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            7277..8752
                     /locus_tag="VVK04_001085"
     CDS             7277..8752
                     /locus_tag="VVK04_001085"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU3989750.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLERQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            8749..9597
                     /locus_tag="VVK04_001086"
     CDS             8749..9597
                     /locus_tag="VVK04_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU3989751.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            9612..10382
                     /locus_tag="VVK04_001087"
     CDS             9612..10382
                     /locus_tag="VVK04_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU3989752.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLTTIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(10660..10947)
                     /locus_tag="VVK04_001088"
     CDS             complement(10660..10947)
                     /locus_tag="VVK04_001088"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU3989753.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            11145..11423
                     /locus_tag="VVK04_001089"
                     /pseudo
     CDS             11145..11423
                     /locus_tag="VVK04_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11533..11736)
                     /locus_tag="VVK04_001090"
     CDS             complement(11533..11736)
                     /locus_tag="VVK04_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU3989754.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(11767..12375)
                     /locus_tag="VVK04_001091"
     CDS             complement(11767..12375)
                     /locus_tag="VVK04_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU3989755.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(12414..12584)
                     /locus_tag="VVK04_001092"
     CDS             complement(12414..12584)
                     /locus_tag="VVK04_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU3989756.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(12596..13162)
                     /gene="amaP"
                     /locus_tag="VVK04_001093"
     CDS             complement(12596..13162)
                     /gene="amaP"
                     /locus_tag="VVK04_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU3989757.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(13246..13410)
                     /locus_tag="VVK04_001094"
     CDS             complement(13246..13410)
                     /locus_tag="VVK04_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU3989758.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            13853..15334
                     /locus_tag="VVK04_001095"
     CDS             13853..15334
                     /locus_tag="VVK04_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU3989759.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            15696..16697
                     /locus_tag="VVK04_001096"
     CDS             15696..16697
                     /locus_tag="VVK04_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU3989760.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            16845..17762
                     /locus_tag="VVK04_001097"
     CDS             16845..17762
                     /locus_tag="VVK04_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU3989761.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            17773..18663
                     /locus_tag="VVK04_001098"
     CDS             17773..18663
                     /locus_tag="VVK04_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU3989762.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            18692..20308
                     /locus_tag="VVK04_001099"
     CDS             18692..20308
                     /locus_tag="VVK04_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU3989763.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYSKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            20318..21637
                     /locus_tag="VVK04_001100"
     CDS             20318..21637
                     /locus_tag="VVK04_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU3989764.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHMDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDCFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            22044..22457
                     /locus_tag="VVK04_001101"
     CDS             22044..22457
                     /locus_tag="VVK04_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989765.1"
                     /translation="MKNNERLGIKLSRDSVLGLKEVRRLYLGSPDIPVSDGYLIKVAY
                     KEILNDIDNIDWLELNNSKLKISDISESVDMNATSLRTTLTLDMLVYSGMRDIQLKLR
                     ELTKGRVFFSFVVKLVLFAAILKKKGLLEKFQEKC"
     gene            22700..23218
                     /locus_tag="VVK04_001102"
     CDS             22700..23218
                     /locus_tag="VVK04_001102"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989766.1"
                     /translation="MNTETFKQKFIDGGYECPRSNEQTLRLQNIHFEYNLGFVFDKDS
                     QTYLRKILRLPYTYPCSMKMANSILLANMLVHKSTRETLVEWLNEEKQIHLDSFFLNM
                     NSSKYIKDGLLEEIRKNHRSIARKATPSNISLIEKELNYNSDLFYYYINALGWKHVKR
                     SYLVKCLAGAIA"
     gene            23318..23722
                     /locus_tag="VVK04_001103"
     CDS             23318..23722
                     /locus_tag="VVK04_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU3989767.1"
                     /translation="MVSALGGFSARLEFRSFSPLKTLKILQLKTNKELNIDNENNLVF
                     QHFGYAYDVPDIATVNKAIKVMLKELQISPLITTKGARHTYGSYLWHNNIDLGVIAKI
                     LGHKDISMLVDVYGHTLQEKISEEFMAVKSLL"
     gene            complement(23805..23877)
                     /locus_tag="VVK04_001104"
     tRNA            complement(23805..23877)
                     /locus_tag="VVK04_001104"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23842..23844),aa:Lys,seq:ctt)
     gene            complement(24142..25413)
                     /locus_tag="VVK04_001105"
     CDS             complement(24142..25413)
                     /locus_tag="VVK04_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU3989768.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            25683..25922
                     /locus_tag="VVK04_001106"
     CDS             25683..25922
                     /locus_tag="VVK04_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989769.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            26077..26265
                     /locus_tag="VVK04_001107"
     CDS             26077..26265
                     /locus_tag="VVK04_001107"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989770.1"
                     /translation="MTWFEEIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFT
                     IDYTDDELLDKEAVFTTH"
     gene            26402..26581
                     /locus_tag="VVK04_001108"
     CDS             26402..26581
                     /locus_tag="VVK04_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU3989771.1"
                     /translation="MPMTQKEMVKLLTTHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            26618..27070
                     /locus_tag="VVK04_001109"
     CDS             26618..27070
                     /locus_tag="VVK04_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU3989772.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            27361..27831
                     /locus_tag="VVK04_001110"
     CDS             27361..27831
                     /locus_tag="VVK04_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU3989773.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            27850..28938
                     /locus_tag="VVK04_001111"
     CDS             27850..28938
                     /locus_tag="VVK04_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU3989774.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEIAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            28919..29347
                     /locus_tag="VVK04_001112"
     CDS             28919..29347
                     /locus_tag="VVK04_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU3989775.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECAAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            29485..30435
                     /locus_tag="VVK04_001113"
     CDS             29485..30435
                     /locus_tag="VVK04_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU3989776.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHGLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            30437..31180
                     /locus_tag="VVK04_001114"
     CDS             30437..31180
                     /locus_tag="VVK04_001114"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU3989777.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAIL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            31191..32987
                     /gene="pepF"
                     /locus_tag="VVK04_001115"
     CDS             31191..32987
                     /gene="pepF"
                     /locus_tag="VVK04_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU3989778.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHENAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            33234..33788
                     /locus_tag="VVK04_001116"
     CDS             33234..33788
                     /locus_tag="VVK04_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU3989779.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTTGFSSQYGWVHSFAHGADLLKEVVCHPDFPKNRVHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            33899..34567
                     /locus_tag="VVK04_001117"
     CDS             33899..34567
                     /locus_tag="VVK04_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU3989780.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT        10743 a         5656 c         7239 g        11040 t
ORIGIN      
        1 aggatacccg tcgcagaagc gaactgaatc aagatcagta actccgttac gctaaagacg
       61 agagcacaag aagctaaaaa gaggaaatcc cctgcaccca tgcggatatc aataaaatga
      121 gccaaaattc caagtatgag gaaggagacc atgaccagat tccagccaga ggaagctatt
      181 aggattaggt ggaaagtcat ccagaccagt aagggatatt cctgatggtg aaagtcgtag
      241 atacccaagg tcaaaccagc ggtgattagg acgacttgcc ccaaggaaag caattcccaa
      301 gagtaaagca gaaagaggag tcctaagcct agttcaaaga gggcatacca gacaggatag
      361 cgaactttgc agtagcgaca gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa
      421 tctaagggac gcaagggagt ctgacaggaa tcgcagtgac tggctgaact gataatggat
      481 tgctctggaa aacggtcaat gaccaaacca agaaaggaag ctagaatgct cccgacgaga
      541 aaaaaataaa aatcaatcat acttatctat tcgtaaaaaa tgggagaaat agtataatgg
      601 agaaacatag ataagatggt gaggaaaaga tgacaattcg ttttgaagaa aaggtgagca
      661 cagaaaacgc tcaatttgta tgccagtggt ccaactccct aggcaaatcc tttcaagaac
      721 aatggatggg accaaggatt ccttttctac tgacccttca agccttggaa ggagtctttt
      781 caatctttga tgaacaagag tttgtgggac ttatccagaa aatcaggcta gaagacagca
      841 atcttcatat cgggagattt tttatcaacc cccagaaaca ggagcaaggc ttaggtagcc
      901 aggctttaag gaaatttgtt agtttggcct ttgaaaatga agatatagat agtatttctc
      961 taaatgtctt cgaggcaaat caaagagctc agaatcttta ccaaaaagaa ggatttgaaa
     1021 tcgttcaaat ggttgaagca cctgtacgaa aatatagtag attgaaacta gaatagtaca
     1081 cctctacttc taaaacattg ttagaaatcg atttgactgt cccgatcgat tcgtcctgtt
     1141 attatttcat tttactatac attatgaaaa aggggagata ggagtataat tccaaatata
     1201 aagaaagcga acaaaacaga attctgattt tcagaaaaca ggtttattcg ctttttatga
     1261 tatactccct ctttttagcc tatttattaa atgtaataga aaattaagaa tgtagaattg
     1321 tatgatacaa acaaagtgca atagctgagt gtgcggctgt aaaatcattg taaggttcaa
     1381 taatgacttc aggtaggcga ttatagagca gtttgggttt gtagttcatt tcactatata
     1441 gtttttggat gatgtgttga tttgttagta aaggactatg taggtagatt ttttgagagt
     1501 caatcatcat actgatattt aaaatggttt gactaagata gagtaaggct tgatggataa
     1561 gtgtgattat tccagtgtca cctaattgat aagcggttaa aataacttgg atatcaatat
     1621 catcggcatt tttgactaaa ctaggaagta gagaataggg agattgatga tatagaattt
     1681 ttgatttttt gattaaccaa gattctccag caaaagtttg taagcatccc ttgcgcccgc
     1741 agctacattc ttctccctca gatgaaacaa ctgtatgccc tatttctcca atcattagat
     1801 ttcctttccc ataaatgttt ccgtcgtaga tataagaaca gtgcatacct ctagcaaaat
     1861 gaaaataagc aaaattaggg tcattctgtt ggcgactaaa taggcgttta cctatagcca
     1921 tacagttaac attgttagag aaaaacaaag gcttatcaaa gtgggattga atcatttcta
     1981 agtcgatatg ttgccataaa ggattgtttg ttgttatttt ataatcatct aaatagcgac
     2041 caggtagcgc gattccaatt gcttctattt cataatcaga gcagttattt aagaattgct
     2101 ttagtgtctg gttaatgagt tgatttccct tttcttggat taactgttta gtaacaattt
     2161 ctttctcttc ctttaagata tttcctagat tatctcctaa agcaaaagtg aaatgttttt
     2221 cagatagttc acaaccaatg tagtaaaatc gtttagcttg aatgtctagc aggatttttt
     2281 ttctccctac gcttgtatcg tgttcgtctt caccaagttc taagagaata ttttctttaa
     2341 tcagatcatt tgtgatactg ctagttgttg caggtgttat tcctgtttta gtagcgattt
     2401 caattcgtga aatgggacct aatgtgtaaa ctgtttccag tattttagct cttagttgta
     2461 attgtttctt agataaggtc atattagttt tcttcctagt tgtcagattc ttaaaatcct
     2521 atgatttttt gctatggata aatgtagatg ttaatctttt taagcttttc attacttact
     2581 ggtctctttt tattatatat tgataataaa aaataatcaa atgtttacac aaatccttga
     2641 caaggctttc ttatagttgt aaaatataaa taacaaaaga taatcaaata acaacttgac
     2701 gtcaaaaaat aaagataatt gataactttt gataataaaa tatatttaag aggaaaaggt
     2761 tatggaaaaa ttattacaag aaaagttact tccagtagcg gctagattgg gtaataataa
     2821 agcgttggtt tctattcgag acggtattac tctaactata cctttattgt tgataggttc
     2881 attactaatg gttattgcaa gttttcctat tccaggatgg gaaaaatatc tgggtgatat
     2941 tggtgttgct gactatttat ggaagggtgt tgatagtagt tttggattac ttggtcttgt
     3001 agctagtttt ggtatcgctt actttatggc tagacaatac aaagttgatg gtattcctgc
     3061 tggtattgtg tcattatcat cttttattac agttacgcct ttcattagag gagaggctgg
     3121 agcaggaatg cctaccgctt tcatggcatc aaaaggttta tttgttgcta tgattttagg
     3181 attgattaat ggctatatct accaatggtt tataaatcat aatatacaga taaaaatgcc
     3241 ggatggtgtt ccaccagcag tatctaaaag ctttagtgcc attattcctg gtgcagtgac
     3301 tattgttggt tggttgattg tttatgcaat tttagataaa ttaagtttac ctaatcttca
     3361 tgaaattgct caagtagctt tgggaggtcc acttggactt ttaggaaata atgttattgg
     3421 tcttcttatc ttaattttcc ttaatagtag tttttggttt gtaggattac acggaggaaa
     3481 tgttgttaat gcagttatga aaccgttatg gttagctaat ctagatgcaa ataaagtagc
     3541 ttatcaaact ggagaaactc ttccaaatat ttttactagc gtatttatgg ataattttgt
     3601 attcataggt ggcggtggtg caaccatagg tttagttctt gcgttaggat atttagcaca
     3661 taagaagaaa gctagtaaac aactaaaaac tttggcacct ataactgtta tacctggatt
     3721 atttaatata aatgaaccag caatgtttgg cgttcctatt gttttgaaca ttttgttact
     3781 agttccattt atcttagctc caatgtttaa cttactagta gcgtggggag caatggcatc
     3841 aggtttggtt ccgctaactt atacagatcc aggttggact atgccacctg ttataagtgg
     3901 tttacttgct acaggaagta tttctggttc attattacaa attgtattga ttgttttgga
     3961 tgtcttactt tatttaccat ttgtaatagc tattgaaaaa cggtttaagt tattggagga
     4021 ttgagaatga aacgtttaat tagtgcaaat ccatctgaga tattacagat gaatgctgaa
     4081 gaattaaaac aaagtatttt agcaagtgaa ggtagagttg ttctatctga aaatgtagtt
     4141 actcgtgaga catttgttgg ggatataact aattctgaaa ttgctagagc ttttggagct
     4201 gatatgattt tattgaattg tgttgatgtt tttgagccta aaatttatgc tttggatagt
     4261 tcaggtgatg atgttattca tcgcttacac cagcttgttg cttgtccaat tggtgtaaat
     4321 ttggaaccga ttgacccatc tgcaaagatg ctagaggaaa cacaggaaat tgttgcaggt
     4381 cgtgttgcta gtgttgaaac attgaatcga atagaggagt taggttttga ctttgtctgt
     4441 ttgactggaa atcctggaac aggagttagc aatcgagaaa tcattaaggc tgttcaaact
     4501 gctaaggaaa acttttctgg tttgattatt gcaggtaaga tgcacggggc aggagtgaat
     4561 gagcctgtgg cagagctttc tgtcgcagag caattgttgg aagcaggtgc ggatgtgata
     4621 cttgttccag cagttggaac cgttccagcc tttcatgacc aagagttgcg tgaagtcgtt
     4681 gatctcgttc atagtaaggg tgggctagta ctgagtgcta ttggtactag ccaagaaaca
     4741 tctgatacag atactatcaa ggaaattgca cttagaaata aaatttgtgg agttgatatt
     4801 caacatatag gtgacgcagg atatggggga ctggcaacag tcgataatat ttatgcattg
     4861 agcaaggcaa ttagaggagt gagacataca gtatctcgct tggctaggtc agtaaatagg
     4921 tgataaagga gtaagctatg gctaaagtaa caattatgtt agcatgtgca gcaggtatga
     4981 gtacaagtct gctagtgaca aagatgcaaa aggcagcaga agataagggg ttggatgcag
     5041 aaatttttgc agttccagct cctgaagcag aagaaattgt agcaacaaaa gaagtaaatg
     5101 tgttgctttt aggtcctcaa gttcgctatt tactagggga ctttcaagaa aaactaaaag
     5161 atagacagat tcctgtggcg gttattccga tgacagatta cggaatgatg aatggttcta
     5221 aagttttaga tttagctgaa agtttattag actaagattg aggagaatgc tatgaatgaa
     5281 agtaatttag aatctgtaat ggggctaatt atgtatggtg gggaagccaa aagtaatgct
     5341 atggaggcta ttcaggcagc aaaaaaaggg gatttctcta aagccaatcg aagattagct
     5401 gatgcgaatg ctgccttatt acaggcgcat aaggctcaaa cagaaatgtt gacaagagag
     5461 gcacaggggg aagaaacatc aattagcctc ttgatggtac acgcgcaaga tcatttaatg
     5521 acgagtctga cctttgttga cttggcgaaa gaagtggtag aagtatacga acgatttgaa
     5581 aaaaattagg agtttagtat gaatacaatg ttggataaaa tgcaagaaaa actttctcca
     5641 attgcaatga aagttgggaa tcagaagttt ttagttgctt tacgtgattc atttgtgggg
     5701 actatgcctg ttattatgac aggttccatt gctttgttat taaatgcttt tctagtggat
     5761 ttaccacaac aatttcacct agaaagtatt acgaaaacct ttcagtggct tgttgacatc
     5821 aataatttgg tattcaaggg aagtatacca attgtttcct tgttgttcat ctattgcttg
     5881 ggagtgaata tcgctaagat ttataaggtt gatacagttt ctgctggttt ggtatcgctt
     5941 gcttcgtttg tcatttcgat tggaagtaca gttacaaaga gtttcccttt ggcaaatgta
     6001 ggagatgtga aattagatca aatcttacaa ggaattgata atctagcatt tgatggtaaa
     6061 aatctgatgg taactattgg gaatgtgatt ccaggaaacc atattaatgc cagaggctac
     6121 tttacagcca tgatgattgg atttttagcc tctattattt tctgtaaagt aatgaaaaag
     6181 aactgggtaa tcaagttacc agattcagtt ccccctgcga ttgctaagcc gttcacttct
     6241 atcattccag gatttatggc gatgtatata gtagctatct tgacttatgt tttccattta
     6301 cttagcaatg acttattgat tgattgggtt tacaaggtgt tacaaacgcc attactaggt
     6361 ttgtctcaaa gtttctttgc agttattctg atgatctttt tgaataagtt attctggttt
     6421 tttggtctcc atggaggaaa tgtattggct cccatcatgg aagggctgtt tggagttgct
     6481 atgttagcga atctggatgc tttccaaaaa ggtgaaccga ttccttatat atggacaagt
     6541 gggtcttttg gggcgtttgt ctggtttgga ggattaggat tagtacttgc tattttaatt
     6601 ttttcaagaa acagtcatta tcgaaaagtt gctaaacttg gtctagcacc agttctgttt
     6661 aatattggtg agccggtcaa ttatggttta ccagttgtct tgaatccttt gctatttata
     6721 ccatttgtac ttagcccggt tttcatggca acggtagctt actgggcaac aagctggggt
     6781 cttgtttcat ctgttacaca aaatgttact tgggtaatgc cgccaatttt atatggtttc
     6841 ttctctacag catttgattg gcgtgccatc atcttatcag ttgtttgttt gattattagt
     6901 gtcttgactt atttcccatt tgtgaaaatg gcagataaaa ctgaattgag ttaatggtct
     6961 tacttgtgtt ttttgtgata aaatagaaat agattacgtg taagatgagt taggtgtagg
     7021 atttcttatc tccactaaaa ttgttattag acaaaggttt ataatttatt gaagttggaa
     7081 tagtacactg taacttctaa aacagtacta gaaaatgatt tgaatttcct aatcgattta
     7141 gtcatatttt agttcatttt tctataaaac ataacaagaa tgttattgtt ttatatagag
     7201 agattgatat agaaaggggt gcagtaaagg tagatatctt cttgtgcctc ttttgccata
     7261 ttagaaagga gattttatgg ttcagacaaa acagccaaat attattttga ttgttgtaga
     7321 tcaaatgaga gcagacgcct tatccttgaa tagtaaggat aagctagtta gcactccaac
     7381 attagatatg atggctagtg taggttataa ttttgaaaat gcctattctc cagttccttc
     7441 ttgcgttcct gctagggcag ctttattgac tggcttagac caagataaaa gtggacgagt
     7501 tggttatcaa gatgaggtgc cttggaattt tactaatact cttccaaaag tctttaaaga
     7561 tatgggttat caaacagagt gtattggtaa gatgcatgtt tttccttcca gacagagact
     7621 tgggtttgat catgtcttac ttcacgatgg gtatctacat gttgatagaa agtatgataa
     7681 ggcttatgga agtcaatttg attatgctag tgactatcta gcctttttaa agggtaaagt
     7741 tggttatgat gttgatttga ttgatgacgg aatggattgt aattcttggg aagctagacc
     7801 ttgggataaa gatgagaagt tacatccaac aaactgggtt gtgagtgagt ccatttcatt
     7861 tttacaaaga agagatccaa cggttccttt ttttctcaaa atgtcttttg aaaaaccaca
     7921 tgctccatta aatcccccaa aatactattt tgatatgtat atggaacgct tgcctcaatt
     7981 tctcgatttg catatcggga attgggaagt attagaaagg caaattccgt ctatttatgc
     8041 tttaagaggg aaattaaagg aagatgatca aagaagaatg gttgctgctt attttggatt
     8101 gattactcat atagaccatc aaattagtcg ctttttgact gccctaaaag aatttcgtca
     8161 tgataaagat acgattatct ggtttgtttc ggatcatgga gatcagcttg gtgaacatta
     8221 tctgtttaga aagggatatc cttatcaggg aagtatccac attccttcgt ttatttacga
     8281 tccggctgga ttgatagctg gtaatagggg aacaatcaag caattagtga aaattcaaga
     8341 tatttttcct tcactcgtgg atttggcagg aggaactact acagatgaac tagatggacg
     8401 gagtgttaag aatttattat ttggacagta cgaggggtgg cgaacagaat ttcatggtga
     8461 acatgcttta ggaaaagatt ctagtcaata tatcttgaca gaccagtgga aatttatctg
     8521 gtttcctgtt ttaaatcatt atcagttatt tgatatgaaa aaagatccgc atgaaatgaa
     8581 tgatttgtat ccaagcgaaa aataccaacc tattgttcgt cagatgaaga aaaaattagt
     8641 agactttctt agatatagag aagaaggttt tgttgtggat gaagagttag ttcctgttga
     8701 actttctaaa ataacgccaa ctctaacgaa aacgggggat agtcaatcat gaaaatgaaa
     8761 aaaatcaagg gtgggacatt tatgatggga acaaattctg aagagggctt tttagatgat
     8821 tttgaaggtc ctcaagtcgc tgttagtgta aaggattttt ccattgcgga tactccagtt
     8881 acgaatcaag aatttgctca atttgtgaaa gaaacaggct ataaaacact agctgagcga
     8941 caagagtggt cttttgtttt tatattgttc gttccagagg cagaaaggga gggatatcct
     9001 catcctgctg gggctccgtg gtggttacaa gttccgaacg cttgctggaa acatccctac
     9061 ggtgagaata gtaatctagt gggtttagaa gaccatccag tagttcatgt tgctttagaa
     9121 gatgcattgg ctttctgtaa ttggagcgga atgtctttac cgactgaagc acagtgggaa
     9181 tatgctgcta gaggaggaag acaatctgaa tatccttggg gagatactct tttagaaggt
     9241 ggatactatc atgccaatac ttggcaagga agatttcctt atgaaaatac tgccttagat
     9301 ggatttatag gaacggctcc tgtctatgaa tttttaccta atgattttgg tctatatcaa
     9361 atgattggga atgtttggga atggtgtcgc aatccgagat ataccttatt agctagtttt
     9421 aatgaagatg actatgagtt gccaaaatat gggatacaag atgaggagta tgctatcaga
     9481 ggaggttcct ttttatgtca ttgttcttat tgtaatcgat accgagtagc tgctagaaat
     9541 ggatgtatct ctacttccac tagtagccat ctaggtttta gatgtttgaa agaataggat
     9601 ggacttaaaa agtggttgag attatttatt ttctaatcat tataatagct agtggattgg
     9661 gttctatatc aggcatgggt ggtggaatta taattaagcc acttatggat agttttggat
     9721 accattcggt cagtgatatt gctttttatt ctagtttctc tgtttttata atggcgatta
     9781 tttcaacaat caaaagattt tcacaaagta aagagataaa atggagattg atttttacgg
     9841 tatccttttc ttctgtttta ggaggatttc taggtcatct tatttttcaa gttttgttat
     9901 ctcaattatc agtacggcta gtatccattg ttcaaatgat tttactattt gtgatgctac
     9961 ttgtatcatt tgttttaaca gattttaaaa aaacttatca atttgataag ataggattct
    10021 atatgatttg tggtcttcta ttgggcttga tttctagttt tttagggatt ggtggtggtc
    10081 cgctcaatgt atctttattg atggtgtttt tttctatttc gataaaagaa gcaacgatgt
    10141 attctcttgc aattattttc ttttcccagc tgtctcattt gactacaatt gttgtggtta
    10201 caggtttaaa tcagtatcat ttagcacctg ttccagttat ttttcttgct tctatatgcg
    10261 gaggggtatt ggggacggtt gtatcaaaag tcttacctga aaattgggta agatactgtt
    10321 ttaaagggat gttattcttt gtcatgggaa tgactttata taatttattt catattttgt
    10381 aaggtcagtg tgaaaatatt taaatagact tcctgtaaaa actggattta acgccctcca
    10441 tttgtcaaat taagctagac agtcttacca actcagaaaa tacctgatga ggtatttggt
    10501 atccaaagga tttaggtggg atgtgatttc ttgaggctgg gaaaaagtct ttaaaattaa
    10561 aaaatgcata atatcaggtg ttggaaaaac tttgatacta tgcattttat tgtgggaata
    10621 tttatttcat tttctcctga aattgagttt ttacccagcc taaaattctt gactgacttc
    10681 gttgaaatct gtctgctttg gcaagtcatg acaccttaaa agtctatttg aatgttcgtt
    10741 gagacaccgc tgtcttggac atcctagatt cgcaaaaaag ctctcactat cgtgatgatt
    10801 ggaaatatct ttccattttg aaaactcttt tccacagtca aacgtaatag atttaaagag
    10861 gttcactaga aattgtgcca gccacccttg gatggattct gccatatcct ttgccttacg
    10921 actcttggtc ttcaaactga caatcaattg actatacctg ttcgctcaca aataggagag
    10981 aactttttac gaaaatctaa tgaatatgcc acaagaacat tataccgcaa cgtgtactat
    11041 ttttggttca ttttactata gaaactattg aagcacctgt acgaaaatat atcatgaaaa
    11101 aggggagata gaaagcaaac agccttgaaa tcaatgttga ctgcgattat gaacctgaat
    11161 cagcccctca aaagggactg tatatgaatg aacgttacca gtgtttaaaa actaaagaat
    11221 atcaggcact tttatcttcc aagggtagac aaattttcgc taaacgtaag attgatatga
    11281 aatctgtctt tgggcagata aaggtttgtt tgggttataa gagatgtcat ctgagaggta
    11341 agcgtcaagt gagaattgac atgggattca tactcatggc caacaacctg ctgaaatata
    11401 ataagagaaa gaggcaaaat taaaaagcta gagttccgca attgggaatc tctagctttt
    11461 tgttttctga gaatcatctt gactcagact cttttgacta atgttaccaa aaagataaag
    11521 taacttttaa ccttatttat cgtcgccact caacatgttt ttaacacctt ctacagcacc
    11581 ttctacagcg tctttagcgt cttcggcaac ttcttttact ttagaaacaa ctttttcagc
    11641 tgctccttct ttttccattt tttcatcacc gatggctttc ccaacacctt ctttaataga
    11701 acctttagct tgatttaatt tttcttctac tgacatgata atttctcctg ttatatttat
    11761 tttatcttag tttacacgag tgttttcgtg agatactaca ccatttgctg cacctttaac
    11821 agcttctaca ccttcgctaa ctttttcttg aacagttgag aaaccagatc caagaccaga
    11881 tttagctttt tcgaattgtt ctgaagtgaa ttctcctgtt gattcagcaa cgtcagatac
    11941 gcgatcttga aggcttactg agtctgcttc atgctgttct ttagttttga tgtcgacaac
    12001 gtttacgttg atttcaacaa tttccaagtc agtcatttta gcaacttctg aagatacgat
    12061 ttctctgatt tctgaatata aagctggaac atttttttgg tactcaacaa taacgtttaa
    12121 gtcaactgca acttgtgttt taccaacttc tacgttaaca ccacttgtta cgtcatcgct
    12181 gttaacgatt ttttctttaa gatttgagaa gaaaccacca tcgattccca aaagacctga
    12241 aacgttttct agtgaaagac caatgatttt ttggataact ttatcttcgt aagtaagctc
    12301 ccctttgatt tcgtgagcta caacagtagc atctttcttt tctacgttag tgtttgtgtt
    12361 tttttcgttt gacatatgaa actcctttaa ttaaattagt aatttttatt tttttattta
    12421 tctatatagt ttttttcgat atataatcca gctgcaactc ccagtgctcc taaaatcaat
    12481 acaaatattg ttttgaagaa gccaaaggag acaatcaaac aagccagaaa tacgcctatg
    12541 agaccagcga taattggata tcgatattgt ttaagccatt ccatttttta cttccttact
    12601 tcacacgact aacagtcttt ttgttttgag gttttggttg gtaatttttt actgcaactt
    12661 caagttttac ttgacgctca ataccaaaaa actgcttcaa tccattagtt atttcatttt
    12721 gaattatttg gcatctgtca gcgatgttgt ctgaaggaag aattttacct tctacatgaa
    12781 cgaaacattt attttttcgt aaatttacat gaacagttgg gttcttgatc aatctatgat
    12841 cactcaccaa acttctaaca aaaccttcga ttgccgaatt ctttaatttt aatgtatcgt
    12901 ttttagtttc aagttggatt tccaagtaac gtttaggata aaacatcaca actaaaatgg
    12961 ataataaaac taaagttgat agaaccactg tcccccaaaa gacatatcta gcaagataga
    13021 attcaactac ggagttctgt ctccagctaa gtagatgaat acctagatca ctaacttgat
    13081 gataatctat caaaacagga aggaaaattg tcaagattaa aatacagaaa ataatgaaac
    13141 atattttctt tgcttttgac atatacaatc ctttcgattt aacatttaaa ctatttttcc
    13201 cgtcattgat ttaaaaatag tttgctaact ttactggcga aaagtttact ttctacctgt
    13261 aaagaatgac actacagtaa tcacaatcgc tgcacctaca atagatggga gcaaagccat
    13321 tccagcgatt gatggacccc aactacctaa aagagattgt cctgcatatg ccccgactaa
    13381 accagcgaat acatttgcga tgattcccat agaactactt ttttagtgat tttacctgcc
    13441 aagagaccaa taagacctcc agcaataatt gatcacaaca ctgcctaccc tcctttttta
    13501 ttttaatatc aaaaaatcaa tttctttgat taatactatt atataacttt aatatagaaa
    13561 agtcaattat ttcgattgtt attattatat aattttaaaa aatcaaattc tttaattgtt
    13621 gctattatat aatttttaaa attaaaaata taatctttag acttgaattt gattctgtat
    13681 tcacgccctc aatagacggt aaaataagaa aattgtttat atattgtctc cgtagtgtta
    13741 ttatacgaaa taaaagattt taggaaaagt cgttatatca tgctatacct attctttgtg
    13801 gtataattgc aagaggttta atccgataat ttataaagag agaaagatat tcatgagaga
    13861 tttattatct aaaaaaagtc ataggcaatt agaattatta gaattattat ttgaacataa
    13921 acgttggttt catcgttctg aactagcaga gttattaaat tgtacagaac gtgcagtcaa
    13981 agatgatcta tcccatgtta aatctgcttt tcctgacttg atttttcatt cttctactaa
    14041 tggtatacgc attattaata ccgatgatag tgatattgaa atggtttacc atcatttctt
    14101 taaacattca actcattttt cgattttaga attcatcttc tttaatgaag gttgtcaagc
    14161 tgagagtatt tgtaaagaat tttatatcag ttcatcttcg ctctatcgta ttattagcca
    14221 aatcaataaa gtgattaaaa ggcaatttca atttgaagtc agtctgaccc ctgttcaaat
    14281 cattggaaat gagagagaca ttcgttactt ttttgcacaa tatttttcag aaaaatatta
    14341 tttcctagaa tggccatttg aaaatttttc atcagagcca ctatctcaat tgttagaatt
    14401 ggtttataag gaaacaagct ttccaatgaa tttgtcaacg catagaatgc taaagttgct
    14461 cctagttacg aacctatata gaataaagtt tggtcatttt atggaagtag ataaagattc
    14521 ttttaacgac caaagtttgg attttttaat gcaggcagaa ggaatagaag gtgttgctca
    14581 gagttttgaa tcagaataca atatctcttt agatgaagaa gttgtttgcc aattatttgt
    14641 gtcttacttt caaaaaatgt ttttcataga tgaaagtctc tttatgaaat gcgtaaaaaa
    14701 ggatagttat gttgaaaaat cttaccatct attgagtgat tttattgatc agatttcagt
    14761 caagtatcag attgaaatgg agaataagga taatctgatt tggcatctgc ataataccgc
    14821 acatctgtat cgtcaagagt tgtttactga gtttatttta tttgatcaaa aagggaatac
    14881 aatcaggaac tttcaaaata tttttccaaa atttgtttca gatataaaaa aagagctttc
    14941 tcactattta gagactcttg aggtttgttc tagttcaatg atggtaaatc atctatctta
    15001 taccttcatc actcatacca aacatttggt gattaatttg ctacaaaatc agcctaaact
    15061 aaaggttttg gttatgagta attttgatca gtatcatgca aaattcgttg cagagacact
    15121 ttcttattac tgtagcaata attttgaact ggaagtttgg actgaattag aattatcaaa
    15181 ggaatcttta gaagattcat cttatgatat cattatttct aattttatta ttcctcctat
    15241 tgaaaataag agactcatct attcaaataa tataaacacg gtctcactca tatatttgtt
    15301 aaatgccatg atgtttattc gattagatga gtaagcaaaa ataacaaaaa aacgctattt
    15361 cgcgtttgaa ctgtacctca aaagttagac agaaaaaatc taatttttgg ggtgtttttg
    15421 ttaagaaaag accttcaatc atttaagcaa aatgtacatc tagatttata gccctctaaa
    15481 actcttgctt tttttgtaga agatacgaaa aaagccataa aaccaaggct tttcctgttt
    15541 tatgtagatg tttacacatg aaaattgaag tattttcaaa agctaattgg agtgatttta
    15601 ttcatgatgg gataaatgat ctggccaaaa atgattgaga aatagttgct taaaaagcat
    15661 ttgcatgata ctatatattg aaaggaggtg ataatatggt agaacaaaga aaatcaatta
    15721 ccatgaaaga tgttgcttta gaagcaggag ttagtgttgg aactgtttca cgtgtaatta
    15781 ataaagaaaa aggcattaaa gaagtaactt tgaaaaaagt ggaacaagcg attaaaactt
    15841 tgaattacat tccagattac tacgctagag gaatgaaaaa aaatcgaaca gaaacgattg
    15901 caatcattgt accaagtatc tggcatccct tcttttcaga atttgctatg catgtggaaa
    15961 atgaagtcta taagagaaat aacaaattac tcttatgttc tatcaatggt acaaatagag
    16021 agcaagacta tctggagatg ttgcgtcata ataaagttga tggagtggtt gccattacct
    16081 atagtccaat tgaacattac ttgacgtcag gaattccctt tgttagtatt gaccgcacat
    16141 actcagatat tgccattcct tgtgtttcat cagataatga tgcaggtgga agagaagcag
    16201 ctaaacaatt aattagtaaa ggatgtcagc atttagcctt tgtgggcgga cataatacaa
    16261 ccattaatga aaccaaacgt cgtagaattt catttgaaaa gtatgtccaa gagcataaaa
    16321 tacctcttag tatttttgat ttggatgaga cagttactga ctattatgga aaactagaga
    16381 gtttcttgga agaaaattct tctatagatg gaatttttac aatcaacgat tttacagctt
    16441 tggatgtgat tgaaatacta aaaaaaaatg gcaaacgtat tcctcatgat gtccaaatta
    16501 ttggatacga tggaattaaa atggctggag atagagatta tctactttca actattgaac
    16561 aaccattgga agaaatggca aaagaagcgg ttcgtatttt gtttgatata attgatggaa
    16621 agactgttaa tttgcagaca atcctaccag taaaatttgt tgaaggaaaa acaacaaaaa
    16681 atgaaaataa gtcttgacag aaagcgctat caatgataga atgaattcag ataaaaagat
    16741 ttatttttaa aacaaaaatg aaacgtttca aaaaagaaat aaagagacag cgtcaaacgc
    16801 tatcttttct agaaaaaatg aaacgtttca aaaaggaggt tgctatgaat agcaaagcga
    16861 agcaagtttc tctttgggaa agaatcaaga aacaaaaact cttgttattg atgactgtcc
    16921 ccggtttagt tttaaccttt atctttaaat acatccctat gtatggggtt ttaatcgcat
    16981 ttaaagatta caatccttta aaaggaattt tagggagtga ttggattggt ttttctgagt
    17041 ttacaaaatt catatcctct cccaactttg gtatcttgtt agccaacaca ttaaaattaa
    17101 gtatctatgg tttattgctt ggctttttac caccaatcat tcttgctatt atgctcaatc
    17161 aactcttgag tgaaaaagtc aaaaaacgaa ttcagctcat tttatacgca ccaaacttta
    17221 tctcagtcgt tgttattgtc ggtatgattt tcctcttctt ttcagtggga ggaccaatca
    17281 acaattttct ttctatgttt ggaatgaaag ctgacttctt gacaaatcca gacttcttta
    17341 gacccttata catctttagt ggtatctggc aaggaatggg ctgggcttca acgctctaca
    17401 cggcaacatt ggtaaatgta gatccagcct tagtagaagc agcccgactg gatggagcca
    17461 atatcttcca acgaatctgg cacattgata ttccagctct taagcctatt atggttatcc
    17521 aatttgtttt agctgcaggt ggaattatga atgtcggata tgaaaaagca ttcttgatgc
    17581 agacatcgtt aaatttgcca acttctgaaa ttatctcgac atatgtctat aaagttggtc
    17641 ttgtatcagg agactattct tactcaacag cggttggttt gtttaatgca gtgattaacg
    17701 tagtattgct tgttgcagtt aaccaaatcg ttaaacgcat gaataatggt gaaggaattt
    17761 aaggaggaaa gtatgaaaaa ttcgattatg gatacaaaat ttgatagacg tatcttactc
    17821 ttaaataaaa tcattattgt ctttatcgtt ttgatgactt tgcttccttt actttatatc
    17881 gtcgtagcat cctttatgga tcctaaggtt ctggttagta gagggattag ctttaatcca
    17941 gccgattgga ctgtagaagg ttaccagcgt gtattcagtg accaatctat tctaagaggt
    18001 tttatcaatt ctctactata ctcttttgga tttgcagctt taacagtatt gctatctgtg
    18061 tttacagctt atcctctttc taagaaagac ttggttggac gtcgttggat taactacttc
    18121 ttgattgtga ctatgttctt tggtggtggt ttagtcccaa cttacttgct cgtaaaagaa
    18181 ttgggaatgc tcaatactcc atgggctatc attgttccag gtgctgtcaa cgtttggaat
    18241 attattcttg ctagggccta tttccaagga ttgcctgaag aattagttga agctgctgtc
    18301 attgatggtg caaatgattt acagattttc ttcaaaatca tgcttcctct tgcaaaacca
    18361 attatgtttg ttctcttcct ttatgctttt gtaggacagt ggaactcata ctttgatgca
    18421 atgatttata tcaaggatcc aaacttggaa ccattgcaac ttgtacttcg taaaattctc
    18481 attcagagcc aaccaggtca agacatgatt ggagcacaag cggctatgaa tgaaatgaaa
    18541 cgtttagctg aattgattaa atacgcaact attgtcattt ccagcttgcc attgattgtt
    18601 atgtatccat tcttccaaaa atactttgat aaaggaatta tggctggttc acttaaagga
    18661 taaaaaaaga aaaaataaaa ggagttttct catgaaattc aaaacattct caaaatcagc
    18721 agttttgttg acagctagtt tagcagtact tgcagcctgt ggctcaaaaa atacagcttc
    18781 aagtccagat tataagttgg aaggtgtaac attcccgctt caagaaaaga aaacattgaa
    18841 gtttatgaca gccagttcac cgttatctcc taaagaccca aatgaaaagt taattttgca
    18901 acgtttggag aaggaaactg gcgttcatat tgactggacc aactaccaat ccgactttgc
    18961 agaaaaacgt aacttggata tttctagtgg tgatttacca gatgctatcc acaacgacgg
    19021 agcttcagat gtggacttga tgaactgggc taaaaaaggt gttattattc cagttgaaga
    19081 tttgattgat aaatacatgc caaatcttaa gaaaattttg gatgagaaac cagagtacaa
    19141 ggccttgatg acagcacctg atgggcacat ttactcattc ccatggattg aagagcttgg
    19201 agatggtaaa gagtctattc acagcgtcaa cgatatggct tggattaaca aagattggct
    19261 taagaaactt ggtcttgaaa tgccaaaaac tactgatgat ttgattaaag tcctagaagc
    19321 tttcaaaaac ggtgatccaa atggaaatgg agaggctgat gaaattccat tttcatttat
    19381 tagtggtaac ggaaacgaag attttaaatt cctatttgct gcatttggta taggggataa
    19441 cgatgatcat ttagtagtag gaaatgatgg caaagttgat ttcacagcag ataacgataa
    19501 ctataaagaa ggtgtcaaat ttatccgtca attgcaagaa aaaggcttga ttgataaaga
    19561 agctttcgaa catgattgga atagttacat tgctaaaggt catgatcaga aatttggtgt
    19621 ttactttaca tgggataaga ataatgttac tggaagtaac gaaagttatg atgttttacc
    19681 agtacttgct ggaccaagtg gtcaaaaaca cgtagctcgt acaaacggta tgggatttgc
    19741 acgtgacaag atggttatta ccagtgtaaa caaaaaccta gaattgacag ctaaatggat
    19801 tgatgcacaa tacgctccac tccaatctgt gcaaaataac tggggaactt acggagatga
    19861 caaacaacaa aacatctttg aattggatca agcgtcaaat agtctaaaac acttaccact
    19921 aaacggaact gcaccagcag aacttcgtca aaagactgaa gtaggaggac cactagctat
    19981 cctagattca tactatagta aagtaacaac catgcctgat gatgccaaat ggcgtttgga
    20041 tcttatcaaa gaatattatg ttccttacat gagcaatgac aataactatc caagagtctt
    20101 tatgacacag gaagatttgg acaaaattgc ccatatcgaa gcagatatga atgactatat
    20161 ctaccgtaaa cgtgctgaat ggattgtaaa tggcaatatt gatactgagt gggatgatta
    20221 caagaaagaa cttgaaaaat acggactttc tgattacctc gctattaaac aaaaatacta
    20281 cgaccaatac caagcaaaca aaaactagag gttgattatg ggagataaga aatacacagt
    20341 agaaaaagcc aatcgtttta tagcagaaaa taaacatctc gttaatactc aatataagcc
    20401 tgaagaacat ttttcagctg agattggttg gatcaatgat ccaaatggat ttgtttattt
    20461 tcgtggagaa taccatctct tttatcaatt ctatccatat gatagtgttt ggggacctat
    20521 gcactgggga catgctaaaa gtaaggactt ggtgacttgg gagcacttgc cagtggcact
    20581 tgctcctgat caagattatg accgaaatgg ttgtttctca ggctctgcca ttgtcaagga
    20641 tgatcgcctc tggctcatgt acactgggca tatcgaagaa aaaaccggtg tccgccaagt
    20701 gcaaaatatg gcattttcag atgacgggat tcactttgaa aagatttccc aaaatccagt
    20761 tgtaactgga acagacttgc cagatgagtt gattgctgct gatttccgtg atccaaaact
    20821 ctttgaaaaa gatggacgct attactccgt agtagctgcc aaacacatgg ataatgtggg
    20881 ctgtatcgtt ctactagggt ccgataacct agtagaatgg cagttcgaat ccatcttttt
    20941 aaaaggggga gaacaccaag gctttatgtg ggaatgccca gattgcttcg agttagatgg
    21001 gaaagattgc cttattatgt cacccatgcg ttatcagcgt gagggagact catatcataa
    21061 catcaactca tcgcttttgt tcacgggtaa ggtagattgg agagaaaaac gttttatccc
    21121 agaatcagtt caagaaattg atcatggcca agacttctat gcgcctcaaa cattgttgga
    21181 cgatcaaaat cgtcgtatcc tgattgcttg gatgcagaca tgggggcgta cccttccaac
    21241 ccatgaccaa gaacacaaat gggcatgtgc catgacttta cctagaattc taagattgga
    21301 agatggcaaa ctaagacaat tccctgttaa aaaaggccaa tatcaaatcc aaatagataa
    21361 agattgtcat taccacttag gaaatgatac agattatctt gaatttggtt atgacagtaa
    21421 tgcgcagcaa gtttacattg atcgtagcca tcttattcaa aaaattctag gtgaagaaga
    21481 acaggacact agtcgacggt atgtagatat tgaagctaaa gaattggaag ttgttctaga
    21541 taaaaattcc atcgagattt ttgtcaatca aggtgaagca agcttgactg caacttatta
    21601 cttaacggtg ccagctgagc tatcacgaat tgattaaaaa ttaagttatt tctcctaaag
    21661 aaaaagttct ctttctaaaa tagtggaaag aggacttttt gtgttttggg tatataagct
    21721 tagtttatgg tatttgtaaa attggtgttg gattatgatt taaactagtt ttctaaagaa
    21781 tttgaaaaaa attttattta agcaaaaaaa gccctatatt ataagacttt tcctgttgta
    21841 tttaaatgcc ccctacagaa attgtaggag atatgttgct tagatgttct tgattttttg
    21901 gtgctttgta acgtttaaat gagttttttg agtttgtaaa tagtatgtta ccctgcagtt
    21961 gcccggcaaa ttcacgactc attgcttgaa aaaattttta aaatgtagta tagttaatta
    22021 tagattaaca cctggaggaa cagatgaaga acaatgaaag attaggtatt aaattaagta
    22081 gagatagcgt gttaggattg aaggaggtta gaaggcttta tctaggtagt ccagatattc
    22141 cagtttctga tggctatctc ataaaagttg cttacaagga aatattaaat gatattgata
    22201 atattgattg gttagagttg aataattcaa aactcaagat aagcgatatt agtgaaagcg
    22261 tggatatgaa tgctactagc ttgagaacga ctttgacttt agatatgtta gtatattctg
    22321 gtatgagaga tatacagttg aagctaagag agcttacaaa agggagagta ttcttttcat
    22381 ttgtagtgaa gttagttttg tttgctgcta ttttaaagaa aaaaggttta ctagaaaaat
    22441 ttcaagaaaa gtgttaatca agtattgact ttttagttga gttcaagtat actttaatta
    22501 gagagatttc tctctaaatt ttttcgcttc ttttgtgtta atcaatgaca aactctttgt
    22561 cttatttttt aacgcttggg tgtgttaatc aaagatgtat atattggagg atgaagatga
    22621 aagctagagc ttcacctatt aagaaaaatt gttaattgtt gataaaaata attcacgagt
    22681 aaaaaaggag tattaaataa tgaatactga aacattcaaa caaaaattta ttgacggagg
    22741 gtatgagtgc cctagaagca atgagcaaac tttgagattg cagaacattc attttgagta
    22801 taatttaggt tttgttttcg ataaagactc acaaacatat ctgcgaaaga ttctacgttt
    22861 accttatact tatccttgtt ctatgaaaat ggctaattct atcttattag caaatatgtt
    22921 agttcacaag tcaacacggg aaactttggt agagtggctt aacgaggaaa aacaaataca
    22981 tttagattca ttctttttaa atatgaattc ctcaaaatat attaaagatg gtttgctaga
    23041 ggagattcga aaaaatcatc gttcgattgc tagaaaagct acgcctagta atatttccct
    23101 tatagaaaaa gaactaaact ataatagcga tttgttttat tattatatta atgcattagg
    23161 gtggaaacat gttaaacgtt cctatctagt taagtgcctt gcaggggcta ttgcttaatt
    23221 tgttattggg ggagcctccc ccatttatat atttaaacaa aggagaaaaa atatgtttaa
    23281 gaatttttgc caaaatgctt ttattagcct atatttcata gtatcagccc taggaggctt
    23341 ctctgcgcgt ctcgagttcc gttcattctc cccgttaaaa acattgaaaa tattgcaatt
    23401 aaaaacaaat aaagaattaa acattgacaa tgaaaataat ttggtttttc agcattttgg
    23461 ttatgcctac gatgttccag atattgcaac agtcaataaa gctataaagg taatgttgaa
    23521 ggaattgcaa atttctccat tgattactac caaaggagct agacacactt atggtagtta
    23581 tttatggcat aataatattg atttgggtgt tattgcgaaa attttaggac ataaagatat
    23641 ctctatgctg gttgacgttt atggtcacac attgcaggaa aaaattagtg aagagtttat
    23701 ggctgtgaaa agtttgttgt aaaaacacgg caaattgcac gacaattttt aaaaggaagg
    23761 caaaaaaagc cctatattat aaggcttttc ctgttgtatt tagatgcccc ctacagggat
    23821 cgaacctgtg acccacggat taagagtccg ctgctctgcc agctgagcta aggaggcaaa
    23881 gaaaaaagct gtattggtgc cgaaacttca cggtttgtat tgaacccgcg caattaagca
    23941 ggtgggcaac tcgctctaac tgaagctgtt tccgtgtgag acggcctaca tgctgttaga
    24001 agacttttgt ttccctaata atacaaaaaa tagtcggtca acacttaagt gtgaagtcgt
    24061 acaccacagc gtttctatat ttatatgata ccactttttt aaaaaaaatc aagaggaaag
    24121 tgcaattttt tgaaaaggat ttcagatttt tcgcaaatgg tcgatagctt cctttctttg
    24181 agccaaagcc cgttcatatt taccagtatc ttctgcttgg aaatagtgat gattacgaat
    24241 tttttctggc agatagtctt gctttaccca atttccagga tagttgtgtg gatagagata
    24301 gtcttgggca ttccccagtt ccttgcttcc actgtagtgc ccatcacgta ggtgtcgcgg
    24361 aataggcaag tgccctgatg ttttgaggtc agcaagtgcc ttatccatag ctacataggc
    24421 tgagttggat tttggagaaa gggccaaatc aatcacgaca ttggcaatga gaatgcgggc
    24481 ttcggggaaa ccaatccttt gtgcagcatc cagagcagtc acggtatgaa tctgggcctc
    24541 aggattggct aagccgatat cttcataggc gataacagtc aagcgacgag cgagactagg
    24601 cagatcccca gcctcaatca agcgggcagt atagtggaga ctggcatcca catctgagcc
    24661 acgaatagac ttttgcaggg cagatagaac atcatagtga ccgtctccat ccttgtccat
    24721 agtgatgtag cttctctgaa gactattttc catgatgtct aaggtgatgt ggcgaatgcc
    24781 ctcgtcattc tcaggggtag atagaacagc caagtccagt gagttaaagg cagagcgaag
    24841 gtctccgttt gtagaggttg cgatgaaatc cagcgcatcc tcatctagtt ctattggaaa
    24901 atcaaaacca cgttcagggt tacttagagc tatctgcagg gcctctttga cgtcttggtt
    24961 agacagaggt tccaactcga aaatttgaac acggctacga atggcaggag tgacagagaa
    25021 gaaaggattt tcagtcgttg ctccaatcat gatgaccagt ccactttcca agagaggcaa
    25081 gaggaagtct tgcttggtct tatctagtcg atgaatttcg tctagcaata ggacgagacc
    25141 accagaaaat ttagcttctt ccgagatttc ttgcagtcgc tttttactat caactgtcgc
    25201 attgaaagtt cgaaaggcat acttggtcgt tccagcgatg gcagaggcaa tactggtttt
    25261 gccgattccc ggagggccat atagaatcat ggaggacagg cggttggctt ccaccatgcg
    25321 gcggatgatt tttccaggtc cgaccagatg ctcctgaccg atgacctggt cgatggtttt
    25381 agggcgcatg cgaagcgcga gattgtctgg catagcagtc ctttctaacg tggatttgag
    25441 tagaatgact catctactat atcttactat gtccattcta gcctattagt tgtgatattt
    25501 caatggtttt gtaataatca gggagtgaga tagaatcttt tttactattt aatttaatga
    25561 ggagaagtat cagcatgaga gatttgattt tccttaaagc tcaaaatagg atagttgagc
    25621 ctaaagaagt ggaagtgctg acttgagaaa taatattgct aaatgtcatt gtatgaacta
    25681 taatgaaaag agaggtgata agcaatggaa atgatggacc aagtcaggaa attttgattt
    25741 ttacaaaaca aattcgtcat tggattctta gtgatcaagt tatttcaggg aaaagaaaac
    25801 ttttcttccg ggaagatact ccaaaagaga ttttagattt gtacgaaaac attaaatcta
    25861 aacttgattt tgcttaccaa gaagttcatt ctaataatgg gttgaaaaaa tatgaaaaat
    25921 agaataattg atgtttttga agtagtaaat cgcctccttg taataactgt tgaaaatcct
    25981 gatttcgaag acttgagagt taatcatact caatgaaaat caaagagcaa actaggaaac
    26041 tagccgcagg ctgtacttga gtacggtaag gcgacgttga cgtggtttga agagattttc
    26101 gaagagtatc agtttgtaaa aattggagat aaaaaatata gagtacgcag tgttcctatg
    26161 attcattcaa ctccgcctca atctgtctta gatcgagata cttttacaat tgactataca
    26221 gatgatgaat tgctcgataa agaagcagtt tttactactc attagaaaaa taggtctgaa
    26281 taaattggct tcccttagaa ccacatctag gggcttttat gtataataga ataataagta
    26341 tcactccttt acaatacgtg taacacgtgt tgtaatggtg ttgtcaggag gtaaaagcgc
    26401 tatgcctatg acacaaaaag agatggttaa actccttacg acccatggtt ggataaagac
    26461 tagaggcggt aaaggctccc atattaaaat ggagaagcaa ggggaaagac ctatcacaat
    26521 ccttcatggt gagctgaata agtacactga aagagggata agaaagcaag ctgggttgta
    26581 aaattcagtc cctgcttttt gatatggagg tagtgaaatg ttagttacgt atccagcttt
    26641 attttattat gacgacacag acggaacaga agcgacttat tttgtccatt tcccagattt
    26701 tgaatactca gctacacaag gagaggggat ttctgaggct ttggctatgg ggtcggagtg
    26761 gctagggata actgttgcag atttgataga gagtgatgga gagttacctc agccatcaga
    26821 tatcaatagc ttgtctttaa ttgataatga tccttttaaa gatgatgaag atttcgtgtc
    26881 aacctatgac cttgataaat cttttatttc tatggtatct gttgatgtat cagaatacct
    26941 aggaagtcag gaacccatta aaaagacttt gaccatacca aaatgggcag ataagttggg
    27001 acgagaaatg ggacttaact tttctcagac tttgacagac gctattgcag ataagaaagt
    27061 tcaagcctaa gattaagcgt ggtatcgtgg taatagtcaa taaaaaagca cgtccacttg
    27121 tgctagttac tcgcctattg attttataga tttattagcc ctttcgcggg ctttttatat
    27181 tgatttttat gagaaatgaa gaaatcagac ttttaagaaa atcactgata ccaagggttt
    27241 aaatgaggta atatggtata attaggacat aaaataattt tgtggtaaga tggtagtatc
    27301 tattttagca tatttccgag caatcggggc gattaaagag tcgcatagaa agaggacaaa
    27361 atggcaacat acggattttt agatgtttta gaggaagagt tggacaagaa ctttcccttt
    27421 gactttgaga ttagctggga caaacgcaac catgcggtag aagtgagttt tctattggaa
    27481 gcgcaaaatg ctgcaggtgt ggagatggtg gatgaagacg gagaggtttc atcagatgac
    27541 attctttttg aggaagcggt ccttttctac aatcctgcca agtcaaccgt caatgcagaa
    27601 gactatttaa cggttatccc ttatctacct aaaaaaggat tttctcgcga gtttttagct
    27661 tattttgccc ttttcctcaa agatactgcg gaggttgggc tagataccct catggacttt
    27721 ttggaagatc cagaagcaga ggaatttgtt atggaatgga atcaagaagt ctttgaagaa
    27781 ggaaaagttg gcttggaaga gggagaattt tatccttatc caagatacta ggagttggtt
    27841 ggaggtgtta tgaagaaaat tgggacttat ttggtttatg tgctagctgt tgtctttatt
    27901 atgctagctt ttgcttgtgg aacaatcgca tttgcagagt tggggtattc cgcagtttta
    27961 gcctttactt ttggttatgc cttcgctctt ctaagcatgt atttaatctt tattcttcat
    28021 gagctgggtc atgctttttg tggctacttg acaggctatc ggctggtggc ttttggatta
    28081 ggacatttta ttttgaccaa aaagtcaggc aggtttcatc ttagtagaac agccattctg
    28141 aaaaatgttg gtgctcaata cattggttta aaagaggatg aaagcgatca aagaatcatc
    28201 ctgatgcttt caggaggctt gatggttcat ctcggcttga tattattggc gatagtgttt
    28261 ggatttttga caagaagctg gtattttgca gggacttgga tttttcttaa tttatctttc
    28321 ttcctaaata acattttgcc agtcgacatc accgatggag caaaaatttg ggaattacta
    28381 caacaccctg aaaataccaa atacgcctac ctggtattga gacattctgc tcaaactttg
    28441 ctggctcctc aagaatatga tttgaaagac tttgttcaag cagttcctga ggatgcacga
    28501 gggagttttg cggatggtgt attaggtatg caaggtgaag tttccatttt ggaagggaag
    28561 gaagaaatag ctaaacagca gtttcaagca ttacttgaga ggacaactac tccgatgatg
    28621 cagacagttg cccaactatc cctgcttcat atcgccttgt tggaaggaga ttttgagcaa
    28681 gcggagcaat atgccagtat tcgacaggtt aaatcgtttc tgtctctcaa actgtccaat
    28741 cttcaagtga tacaagcctg gtatcaatta aaggtgaaga aagatgtaga tcgaactcgt
    28801 aaggctctca agattgctag acagaaaatg gatagtagtc gaatgttgag ggacgagaaa
    28861 cgctattatg aaaacttgtt agcagagctg gaaaaggaaa tgttagaagg aactgaagat
    28921 ggaactagaa atttctgatt tcccaggctg taagattgct ttgttttgtg gggataagct
    28981 tttgactatc ttacgcgatg ataaggcaag cattccctgg gccaatatgt gggaactgcc
    29041 aggtggtgga cgtgaaggtg atgaaagtcc ttttgagtgc gcggcgcgtg aagtttatga
    29101 agaactgggc attcatctga ctgaagattg tctgctttgg agtaaggttt acccaagtat
    29161 gctttttgcg gataaacaat ctgtatttct agttggtcag ttgacacaga accagtttga
    29221 cagtatcgta tttggagatg aaggacaggg ctatcagctg atgaatgttg aggaatttct
    29281 tagttccagt caagttgtgc ctcagttgca agagagatta aaagattatt taaaagtaag
    29341 tgattagaaa ggatggttca gttacatttc taaactgaac ccgccctaaa cactgtgcca
    29401 aaaagataaa cttcttttag acacaagcgt cttcagagaa tttcctattt tggttttgtg
    29461 ttttacgggc ttggtatctt aataatggaa acatggcaag agttaaaagt tacagtgaag
    29521 cgtgagggag aggagttggt ttccaatctc ttgattgagc tgggagcgca aggtgttgcg
    29581 attgaagaca gtctggacta tgtgggaaat gttgaccgct tcggcgagat tttcccagag
    29641 gtcgagcagc aagaagaaat cgtagtgacc gcctactacc ctgacacggt ggatgtgaca
    29701 gtggttgagg cggacttgca ggctcgcata tcagaattga cggattttat ggatttggga
    29761 gaagtcaaga tggggacgac tgccttggct gaggaagact gggctgacaa ctggaagaag
    29821 tattatgaac cggcacgcat cacccatggc ctgaccatcg taccgtcatg gacggactat
    29881 gaggcaacag caggagaaaa gattatcaag ctggatcctg gtatggcctt tgggacaggg
    29941 acccacccaa caaccaagat gagcctcttt gccttggaac aggttcttcg tggtggcgaa
    30001 acagtgctag atgtagggac tggttcaggg gttctttcta ttgcaagctc actcctaggt
    30061 gccaaggaga ttttcgccta tgacttggat gatgtggcgg ttcgtgtcgc tcaggaaaat
    30121 attgaactca acactggtat ggaaaatatc catgtagcag caggagactt gcttaaggga
    30181 gttgagattg aagcagatgt catcgtggct aatatcttgg cggatattct cattcatctg
    30241 acggaggatg cttatcgctt ggtaaaggat gaaggctacc tcatcatgag tggcattatc
    30301 aaggacaagt gggacatggt gcgccagtcg gctgagtcag ctggattttt cctcgaaact
    30361 cacatggttc aaggggaatg gaatacctgt gtctttaaga aaaccaagga tatctctggt
    30421 gtgattggag gctagcatgc agcagtattt tgtaaaaggc agtgctatct ctcctgtcac
    30481 tatcgaggac aaggaaacca gtaagcatat gtttcaggtt atgcgcttga aagaagagga
    30541 tgaggttacc ttagtctttg atgatggcat caagcgcttg gcgcgcgtgc tggatatgga
    30601 aaatcgtcag tttgagttgg tccaagaatt aaatgacaat gtggaactac cagtccaagt
    30661 gaccatcgca tctggatttc ccaagggaga caagctggag ttcatcgctc aaaaagtaac
    30721 cgaactgggt gctagccaaa tctgggcctt tcctgcagac tggtcagttg ccaagtggga
    30781 tggcaagaaa ttgggtaaaa aagttgaaaa actagaaaaa attgcccttg gagcagccga
    30841 gcaaagcaag cgtaatattg taccaagtat taaacttttc gagaaaaaag cagattttct
    30901 agctcagctg gaccagtttg actctatcat agtagcttat gaagaatcag ctaaagaagg
    30961 agaagccgct gcgcttctgc aagcagtcac tggtcttgaa acaggagcca aactgctctt
    31021 tatctttggt ccagaaggcg gtctctcacc tgcagaaatc gaaagttttg aagctaaggg
    31081 agccattttg gtaggcctag gtcctcgtat tttgcgagca gaaacagcac cgctttacgc
    31141 cttatcagcc cttagtgttt tagtagaatt agagaaataa gaggaagaaa atggaacaaa
    31201 aacaccgttc agaatttcca gagaaggaac tctgggactt aacagcccta taccaagacc
    31261 gtgaggattt cttgcgtgca atcgagaaag ctcgcgaaga catcaaccag tttagccgtg
    31321 attacaaggg caatcttcac acttttgagg atttcgagaa ggcctttgcg gaattggaac
    31381 agatctacat tcagatgagc catattggca actatgcttt tatgcctcag acgacggact
    31441 atagcaatga cgaatttgcc aatattgccc aagctgggat ggaatttgaa acagatgcca
    31501 gcgtagcctt gaccttcttt gacgatgcct tggtggcagc agacgaggaa gtcttggacc
    31561 gtttgggtga attgcctcac ttgacggcag ccattcgtca ggctaaaatc aaaaaagccc
    31621 actacttagg ggcagatgtg gagaaggcct tgacaaatct cggtgaagtt ttctacagtc
    31681 cgcaggacat ttatactaag atgcgagctg gggattttga aatggctgac tttgaagccc
    31741 atggcaagac ctacaaaaac agctttgtca cctatgagaa tttctaccaa aaccatgaga
    31801 atgctgaggt tcgtgagaaa tccttccgtt ccttctcaga gggacttcgt aagcaccaaa
    31861 atacggctgc agcagcctat ctggctcagg tcaagtctga aaaactcttg gctgatatga
    31921 agggatatga ctctgtcttt gactatcttc tagctgaaca agaagtggac cgtgtcatgt
    31981 ttgaccgcca gattgacctc atcatgaagg actttgcacc agtcgctcag agatacctca
    32041 agcatgttgc caaggtaaat ggtcttgaaa agatgacctt tgcagactgg aaattggact
    32101 tggacagcgc cctcaatcct gaagtgacta ttgacgatgc ctatgatttg gtcatgaagt
    32161 cggtagaacc tttggggcaa gaatattgtc aggaagttgc tcgttaccaa gaagagcgct
    32221 gggtggactt tgctgctaac agtggcaagg attccggtgg ttatgcggcg gacccatatc
    32281 gcgtacaccc ttatgtactc atgagctgga caggccgttt gagcgatgtc tataccttga
    32341 ttcatgaaat cgggcattct ggtcaattca tcttttcaga caatcatcaa agctatttca
    32401 acgcccacat gtcgacctat tatgttgaag caccgtcgac cttcaatgaa ttgctactca
    32461 gtgattactt agagaaccag tctaatgacc cacgtcaaaa acgcttcgct ctggctcatc
    32521 gcttgacaga cacctacttc cataatttca tcacccacct cttggaagcc gccttccagc
    32581 gtaaggtgta tacattgatt gaagaagggg agacctttgg agcaagcaag ctcaacagca
    32641 ttatgaagga agttttgacg gatttctggg gagatgccat tgaaatcgac gacgatgcag
    32701 ctttgacttg gatgcgccaa gctcactact atatgggctt gtatagttac acttactctg
    32761 ctggtcttgt catctcgaca gctggttacc ttcatcttaa aaactcagaa actggagctg
    32821 aagactggct caatctcctc aaatcaggtg gtagcaagac accacttgag tcagccatga
    32881 ttatcggtgc tgatatttca acagacaaac cactccgtga taccatccaa ttcttgtctg
    32941 acacagttga ccagattatc gcctacagtg ctgagttggg ggagtaaggg gaatagaaaa
    33001 attttttaga atgatgttta tgggcttgtt aagcgtcatt ctatttgtct tagttgtagc
    33061 tattttcaaa aatgtcgttg aaggtcgtga tgttaaattt gaacttactg tagaactggt
    33121 attgatagtt atttacgtca ttttatatca gattgtattt aattgagaat tcaatattga
    33181 gtcatttaag actgcctttt tgaacagttg ctagaaatgt agaggtattg accatgtatc
    33241 aagatttact aagaaaaata gcagaagaaa aaccaaatta taaccaggaa gaaatccagt
    33301 ggttgtttga tcatttggga aatccttctc cagaaattcg taatgtcctt ttaaatcaag
    33361 gcttgcacta tctttcaaaa gaaaaggata caacaggttt ctcaagtcag tatggttggg
    33421 ttcattcttt tgcacatgga gccgatttac tgaaagaggt ggtttgtcat ccagactttc
    33481 ctaaaaacag agttcatgaa gtatttgaca tacttggcca actatttaaa agaatgtcga
    33541 ttcgctttac agatgatgag gattggcgtt tagcaagagt gatctatgaa cctattttac
    33601 aagggaagtt ggagcaagaa caagtagctt cttggataaa aactgttgat tttccgatag
    33661 aagaaaggga ggatttttac aaattttcca actttagatc ctgtctggtg gaagtctatg
    33721 tccaacttga ccagagaaat agtttacaag atgacctgaa agaagctatc cagtcttttc
    33781 aatactaggg attagctaat agttctgtga ttttcaaaaa atttccaatc aattttcttg
    33841 aaaccctttc ctacttttga tagactagta tctagttttt gaaaaaagga gaaagaaaat
    33901 gaaaaaattt gttgctgagt taatcggtac gttcatgctt gtgttcgttg ggacaggagc
    33961 tgttgttttt ggaaatggtc ttgatggcct tggtcacctt ggaatcgcct ttgcctttgg
    34021 tttggcaatc gtggtggcgg cctactcaat cggaactgtt tcaggtgctc acttgaaccc
    34081 ggctgtttcg attgctatgt ttgtaaacaa acgtttgtca tcttcagaac ttgtaaacta
    34141 catccttggt caggttgttg gagctttcat cgcttctggc gcagtcttct tcctcttggg
    34201 taattcaggt atgtcaactg ctagtcttgg tgaaaatgcc ttggcaaacg gtgtcactgt
    34261 ctttggtggt ttcttgtttg aagtcatcgc aactttcttg tttgtcttgg ttatcatgac
    34321 tgtgacttca gaaagtaagg gcaatggcgc gattgctggt ttggtaatcg gtttgtcatt
    34381 gatggcgatg attcttgtcg gattgaagat tactggactt tcagtaaacc cagctcgtag
    34441 cttggcacca gctgtcttgg taggcggcgc agcccttcaa caagtttgga ttttcatcct
    34501 tgcaccaatc gctggtggag ttcttgcagc ccttgttgca aaaaatttcc ttggaacaga
    34561 agaataattg aaactcaaaa agccttgctc ctcatcttga ggaacagggc tttttcgtat
    34621 gatactcttc gaaaatctct tcaaaccacg tcagcttcac cttgccgtag gtatggtt
//
LOCUS       DAVHBD010000022        33403 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000022 DAVHBD010000000
VERSION     DAVHBD010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.022"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..379
                     /locus_tag="VVK04_001118"
     CDS             <1..379
                     /locus_tag="VVK04_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU3989781.1"
                     /translation="RNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPK
                     PTEEPEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLF
                     GTQDNNTIMAEAEKLLALLKESK"
     gene            801..1175
                     /locus_tag="VVK04_001119"
     CDS             801..1175
                     /locus_tag="VVK04_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU3989782.1"
                     /translation="MESIGLVIVSHSKHIAEGVVELISKVAKDVPITYVRGTEGGGIG
                     TSFEQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNAAA
                     LLQAGAELSVIQTQLAELEINK"
     gene            1633..2346
                     /locus_tag="VVK04_001120"
     CDS             1633..2346
                     /locus_tag="VVK04_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU3989783.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2404..3006
                     /locus_tag="VVK04_001121"
     CDS             2404..3006
                     /locus_tag="VVK04_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989784.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3144..3797
                     /locus_tag="VVK04_001122"
     CDS             3144..3797
                     /locus_tag="VVK04_001122"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU3989785.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3807..4271
                     /locus_tag="VVK04_001123"
     CDS             3807..4271
                     /locus_tag="VVK04_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU3989786.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4284..5552
                     /locus_tag="VVK04_001124"
     CDS             4284..5552
                     /locus_tag="VVK04_001124"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU3989787.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIINIAPEIKEEGAEII
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQEVLQSAAKEKINVKTVATITKNFNGQDLTDFKALLEAGAVGFSDDGIPLESSKVV
                     KEAMEEAKKLNTFISLHEEDPGLNGILGFNENIAKEHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5566..5826
                     /locus_tag="VVK04_001125"
     CDS             5566..5826
                     /locus_tag="VVK04_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989788.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5837..7198
                     /gene="pdrM"
                     /locus_tag="VVK04_001126"
     CDS             5837..7198
                     /gene="pdrM"
                     /locus_tag="VVK04_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU3989789.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSPLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7352..8320
                     /locus_tag="VVK04_001127"
     CDS             7352..8320
                     /locus_tag="VVK04_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU3989790.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8336..9328
                     /locus_tag="VVK04_001128"
     CDS             8336..9328
                     /locus_tag="VVK04_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU3989791.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9546..10589
                     /locus_tag="VVK04_001129"
     CDS             9546..10589
                     /locus_tag="VVK04_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU3989792.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10653..12338
                     /gene="lpdA"
                     /locus_tag="VVK04_001130"
     CDS             10653..12338
                     /gene="lpdA"
                     /locus_tag="VVK04_001130"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU3989793.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12402..13391
                     /locus_tag="VVK04_001131"
     CDS             12402..13391
                     /locus_tag="VVK04_001131"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU3989794.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13464..14534)
                     /gene="xerS"
                     /locus_tag="VVK04_001132"
     CDS             complement(13464..14534)
                     /gene="xerS"
                     /locus_tag="VVK04_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU3989795.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(15118..16668)
                     /locus_tag="VVK04_001133"
     CDS             complement(15118..16668)
                     /locus_tag="VVK04_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU3989796.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16684..17463)
                     /locus_tag="VVK04_001134"
     CDS             complement(16684..17463)
                     /locus_tag="VVK04_001134"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU3989797.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17450..18301)
                     /gene="ylqF"
                     /locus_tag="VVK04_001135"
     CDS             complement(17450..18301)
                     /gene="ylqF"
                     /locus_tag="VVK04_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU3989798.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18532..18708)
                     /locus_tag="VVK04_001136"
     CDS             complement(18532..18708)
                     /locus_tag="VVK04_001136"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU3989799.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSELTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18760..24423)
                     /locus_tag="VVK04_001137"
     CDS             complement(18760..24423)
                     /locus_tag="VVK04_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU3989800.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPVIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     EPAVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEKNRTATKPENSGNTTSENGQTEPEKKLELRNVSDIELYSQTNGTYRQ
                     HVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQELE
                     NKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELGPDER
                     SYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSLA
                     NEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESSFKGRIVNTYETTDAYNIG
                     GLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLVDQDAHIQNSYAEGDINNV
                     KHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGNAITGYHYTGMKVANTFSS
                     KANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEINPLTLPTVEPLSTSGKKD
                     SDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVKENSLLYQKELLSAVMMKD
                     DQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANLAEYNLGNTGLLYTPNQFL
                     YDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELYLEDQFSKTKQNLGDSLKK
                     LLTADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERWYNFNYGQVNVKDLVMYHP
                     DFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGATDLFSTLEHYRKVF
                     LPNTSNNDWFKSQTKAYIVEEKSTIEEVKTKQGLAGTKYSIGVYDRITSATWKYRNMV
                     LPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDHY
                     DYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEAKFDSSNPAMKNFFGPVGN
                     KVVHNQHGAYATGDSVYYMSYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRNGLGPE
                     FFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVLDPTERFQNAADLQNYVHN
                     MFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDPADGNEVYATNVVKELTEA
                     EARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGDLMGR
                     RIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDGK
                     YKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTKTINNVDELQALMDQAVLK
                     DAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            complement(24632..25810)
                     /locus_tag="VVK04_001138"
     CDS             complement(24632..25810)
                     /locus_tag="VVK04_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989801.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSFIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHQLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSNFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25980..29630)
                     /gene="addA"
                     /locus_tag="VVK04_001139"
     CDS             complement(25980..29630)
                     /gene="addA"
                     /locus_tag="VVK04_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU3989802.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDTKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQVYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKIQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSFQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29627..32902)
                     /gene="rexB"
                     /locus_tag="VVK04_001140"
     CDS             complement(29627..32902)
                     /gene="rexB"
                     /locus_tag="VVK04_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU3989803.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADSKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33102..33257)
                     /locus_tag="VVK04_001141"
                     /pseudo
     CDS             complement(33102..33257)
                     /locus_tag="VVK04_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9597 a         6543 c         6866 g        10397 t
ORIGIN      
        1 aagaaacaaa aatggtcaag ctgataccaa tcaaacggaa aaaccaagcg aggagaaacc
       61 tcagacagaa aaacctgagg aagaaacccc tcgagaagag aaaccgcaaa gcgagaaacc
      121 agagtctcca aaaccaacag aggaaccaga agaatcacca gaggaatcag aagaacctca
      181 ggtcgagact gaaaaggttg aagaaaaact gagagaggct gaagatttac ttggaaaaat
      241 ccaggatcca attatcaagt ccaatgccaa agagactctc acaggattaa aaaataattt
      301 actatttggc acccaggaca acaatactat tatggcagaa gctgaaaaac tattggcttt
      361 attaaaggag agtaagtaaa ggtagcagca ttttctaact cctaaaaaca ggataggaga
      421 acgggaaaac gaaaaatgag agcagaatgt gagttctagt tctcattttt ttcatgaaaa
      481 tgtgcaaaat atagtagatt gaaactagaa tagtatacct ctacttctaa aacattgtta
      541 gaaatcgatt tgactgtcct gttcttattt cattttacta tatcttaaca gatagtgtaa
      601 ataaagataa actatttact ggctaattaa tcagttaaac actagttaag gagtaatgat
      661 gaaaaaaaga acaatactat tattgatggc cagtctgtta gctcttgtct taggagcatg
      721 tggtttcttg gacatattga tcctggatca ttctcatcag gattactctt tactgctatt
      781 ttagaaactg gggtggtttg atggaaagta ttggtcttgt tatcgtttca cattccaaac
      841 acattgcaga aggtgttgtt gaactgatta gtaaagtagc taaagatgtt ccgattactt
      901 atgtaagagg aaccgagggc ggaggaattg gaacgagttt tgaacaagta gatagggttg
      961 tttccgaaaa tccagcagat actttacttg ccttttttga cctaggttct gctaaaatga
     1021 acttaaaaat ggtgactgat ttcagtgata aaagtatcat catcaacagg gttccaattg
     1081 tagaaggtgc ctataatgca gctgctcttc ttcaggctgg tgcagaactg tcagttattc
     1141 aaacacagtt agcggagctt gaaatcaata aataaggaat tttactataa ctctttttat
     1201 aggtaagcta ttgattatct caactataaa atgttaagta aatgatttca aaatcagaaa
     1261 gggattgctt tatgcagttc ctttttattt taacaggagt gaaactatag tgtttctaaa
     1321 ttgtgaatca atcaaaactg attgtgatgg ggctattcta gctttagaaa ccttcaaaaa
     1381 ttaaaattta aggcaatcaa ttacttggaa gagtatgaaa gcatttagtt tataggaatt
     1441 ctaggtctag aattacatat atatttatga atacggggtg ttcgatagtt agtattgttc
     1501 tattctgaaa gatttgagct gtcagttgta tagaaagtgt tcgaattttt ttaagtgatt
     1561 aaattagtta attgtatgag gtgctttatg atataatgtt cttaatgaat tttcagaaag
     1621 gaaaacctca aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat
     1681 tttgatgctg ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat
     1741 attcaggctt ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag
     1801 ctgaagaaaa tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat
     1861 tttggacagg aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag
     1921 cagggacaaa cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat
     1981 aacttgtatg ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct
     2041 ggtctagcac cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg
     2101 gatgctcttt tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg
     2161 ctgatgattg gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgac
     2221 actatctggt ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa
     2281 gtctattctt accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca
     2341 ttttaaagga gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt
     2401 gaaatgtctg aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt
     2461 caattagcaa atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct
     2521 ggcgatttaa tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg
     2581 agaagggatt cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt
     2641 actaatcgaa aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat
     2701 gacttttttg atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat
     2761 aatattaaag agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat
     2821 tttcgatttt tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg
     2881 caagtttcta aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca
     2941 gaaaagataa tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa
     3001 aaatagccag tctttataaa ctgtattcac gtattcaaat cgtatatata gtcgatttat
     3061 taaatcttta gataaactgt aaaaagtggt ttccatagcc actttttgct ataatagagg
     3121 cagtaaaaat gaaggagtcg gctatggaac actcgtcttg gcatgctttg attaaggcgc
     3181 aattacctga gggttatttc gggaaaatca atcagtttat ggagcaggtc tattctcagg
     3241 ggattattta tccacccaag gaaaaggttt ttcaggctct cttgacaaca ctgcttgaag
     3301 aagttaaggt ggtaattcta gggcaagacc cctatcacgg accaggtcaa gcgcagggct
     3361 tgagtttttc tgtacctgac tctatcccag ctccaccatc cttgcaaaat atcttgaaag
     3421 aattgtcaga tgatatcgga gttaagaaat ctcatgattt gacagcttgg gctgagcaag
     3481 gagtcttgct tcttaatgct tgtttgactg ttcctgctgg acaggccaat ggtcatgctg
     3541 gtcaaatctg ggagcctttt actgatgctg tgattcaggt ggtcaatcat ctagatagac
     3601 cagtcgtttt tgtactctgg ggagcttatg cacgtaagaa gaaggcatta gttaccaatc
     3661 ctcatcactt gattatcgaa tcagcccatc caagtccttt gtcggtttat agaggatttt
     3721 ggggttccaa gcccttttcc aaggccaatg cattcttaaa agagacagga caagagccaa
     3781 tcgattggct tagataagga gaaaatatgc ctcagttagc gacgatttgc tacattgata
     3841 atgggaaaga actgctcatg ctccatcgta ataagaaacc caatgatgtc catgaaggga
     3901 aatggattgg tgtgggtggt aagctagaga gaggagagac gccccaggaa tgcgcagcgc
     3961 gtgaaatcct cgaagaaaca gggctcaaag ccaagccagt tctaaaaggt gtcatcactt
     4021 ttcctgaatt tacgccagat ttagactggt acacctatgt ttttaaagtg acggagttcg
     4081 agggtgactt gattgactgc aacgagggaa cgctagaatg ggttccctat gatgaggttt
     4141 tgagcaagcc aacttgggaa ggtgaccaca cctttgttga atggctttta gaggacaaac
     4201 ccttcttttc agccaagttt gtttatgatg gggataaatt gttggatacc caagttgatt
     4261 tctatgaata aaggagaaag cagatgctac taatcaaaaa tggtcgtgta atggatccca
     4321 agtctggttt ggatcaagtg tgtgatgtct tggttcaaga tgggaaaatt atcaacattg
     4381 cgcctgagat taaagaagaa ggagcagaga taattgatgc tactggtctt gtagttgctc
     4441 ctggcttggt cgatatccat gttcatttcc gtgaacctgg tcaaacccac aaggaagata
     4501 ttcatacagg tgccttagca gctgcggcag gtggttttac aacagttgtc atgatggcta
     4561 atactagtcc aaccatttcg gatgtggaga ctttgcaaga agttcttcag tcagctgcca
     4621 aggaaaaaat caatgtcaag acggttgcga ccatcactaa gaactttaat ggccaagact
     4681 tgactgactt taaggcactt ttagaagcag gtgcagttgg tttttctgat gacggtattc
     4741 cgcttgaaag cagtaaagtt gtcaaggaag ccatggaaga agctaaaaaa ctcaatacct
     4801 ttatcagcct tcatgaggaa gatccaggct tgaatgggat tcttgggttt aacgaaaata
     4861 ttgctaaaga acatttccat atctgcggtg cgactggggt ggctgagtac gctatgatgg
     4921 cgcgtgatgt catgattgcc tatgcaacca aggctcatgt ccatattcag catttgtcta
     4981 aggaagaaag tgttaaagta gtggagtttg ctcaggggtt aggtgcagaa gtcacagcag
     5041 aagtagcgcc acagcatttc tctaagacag aagcacttct tttaacacaa ggtagcaatg
     5101 ctaagatgaa tccaccgctt cgtttggaat cagaccgtcg tgccgttatc gaaggtctca
     5161 aatcaggtgt catcacagtt attgcgactg accacgcgcc tcatcatgta gatgaaaaaa
     5221 atgttgagga tattaccaaa gcgccatctg gtatgactgg cttagaaaca tccctgtctc
     5281 tcagcttgac ctatttagta gaagctggtg agttgagctt gatggaatta cttgaaaaaa
     5341 tgacatacaa cccagccaag ctttacaact ttgaagcagg ttacttggct gagaatggtc
     5401 cagcagatat cactattttt gatgccaagg ctgaccgctt tgtggactcc cattttgctt
     5461 ccaaagcagc taattcacca ttcatcggtg aaaccttaaa agggcaggtt aaatatacca
     5521 tctgtaaggg acaaatcgtc tatcaagctt gataggagtt agaatatgaa ttattttcga
     5581 aaacgtaggg agagacaagc gaaatctaat agtggaattt actgtcccgc agctaatcgt
     5641 tccaaaattc aatatgaaac taaagaaaaa gctgaccatg cggttcaata tgataacgga
     5701 ggtttagtta gaagctatta ttgtcgtaca tgtgcgtgtt ggcatactac ttcaaaatct
     5761 aataaacctc cgctaagttt gaaaaactat ggtctgaaac tctttggttt agataaatca
     5821 gaatagaaag agaagtatgt ataagacaaa gtgtttacga gagaagttag tattattttt
     5881 aaaaattttc ttcccaatcc tgatctacca atttgccaat tattctgcct cttttgttga
     5941 tactgcaatg acaggtcaat acaacactat ggacttggct ggtgtatcta tggcaaccag
     6001 tatctggaat cctttcttta catttctaac agggattgtg tcagccttgg tgcctatcat
     6061 tggtcaccat cttggtcgag gcaaaaagga agaagttgcg tctgattttt accaatttat
     6121 ttatttggcc ttgggcctat ctgtggtctt gctggggatg gtacttttct tggcaccaat
     6181 aatcttgaat catattgggt tagaagcagc agtagcggca gtagcggttc gctatctttg
     6241 gtttttatct atcgggatta tccccttgtt gctctttagc gtcattcgtt ccttgctgga
     6301 ttcgctgggc ttgaccaaac tgtccatgta cctcatgctt ttgttactcc ctctcaatag
     6361 cggatttaac tatctcttga tttacggtgc ctttggtgtt ccagaactgg gaggggctgg
     6421 tgctggttta ggaacatcct tggcctactg ggtcttgctt gggatttctg ttctggtttt
     6481 atttaaacag gagaagctca aagccttaca ccttgagaaa cgaattccac ttaatatgga
     6541 taaaattaag gaaggagttc gtttaggtct gcctattggg ggaactgtct tcgcggaagt
     6601 ggctatcttt tcagtggttg gcttgattat ggctaagttt tcgcccttga ttatagctag
     6661 tcaccagtca gctatgaact tttcaagtct tatgtacgcc tttcctatga gtatctcatc
     6721 ggctatggct attgtcgttt cctatgaagt gggagccaag cgatttgatg atgcgaaaac
     6781 ctatattggt ctaggaagat ggactgccct catttttgcg gccttcacct taaccttcct
     6841 ttacattttt aggggaaatg tggccagtct ttatggtaac gacccaaaat ttatcgattt
     6901 gacagtgcgt tttttaactt atagtctttt cttccagtta gcagatacct ttgcggcgcc
     6961 gcttcaggga attttgcggg ggtataagga tacagttatt cctttttacc ttggtttgct
     7021 tggttattgg ggcgtagcaa tccctgtggc tacgctattt gattccctaa cagattttgg
     7081 agcttattct tactggatcg gcttgattat tagtttgatt gtgagcgggg cgctctaccg
     7141 ttggcgttta actgtgatta tgaagagatt tgaatcttta gcaaaatcca aatgctaaaa
     7201 agtttgtgaa aaaatattct tgacaagaaa atcccttgtt ttcacggggt tttctttttt
     7261 attttgtgaa atttctttta gaaaaacttt gacagtattt gccaaaagcg gtaaaatagt
     7321 aaggtaagaa gaaagttaga aaggcaagaa gatgtcaact ttagataaaa atcttttgct
     7381 agaaatgttc cgtaagatgg aagaaatccg tcgcatggac ttaaaaattg cacaattagt
     7441 aaagaaaggg aaagtgccag gaatgacgca cttttctgtt ggtgaagagg cagctaacgt
     7501 gggggctatg ttagctctca atccagatga tctgattacc tcaaaccacc gtggacacgg
     7561 gcaagctatt gctaaaggga ttgacctcaa cggaatgatg gctgaaatcc ttggtaaata
     7621 cactggaacc tgtaaaggga aaggtggatc tatgcatatc gctgaccttg atgctgggaa
     7681 ccttggtgcc aatggtatcg taggtggtgg tatggggatc gctgtcggtg cagccctcag
     7741 tcagcaaatg caaaataccg gtaaaatcgt tgtctgcttc tttggagatg gtgcgaccaa
     7801 tgaaggtgtt ttccacgaag cagtgaacat ggcttctatc tggaacctgc cagtcatttt
     7861 ctattgcatt aacaacggtt acggtatctc tgcggatatc aagaaaatga ccaatataga
     7921 acatatccat caacgtagcg ccgcttatgg aattcctgga atgttcatcg aagacggtaa
     7981 caatgtcatc gatgtctatg aaggatttca gaaagctgtg gaccatgttc gcagtggcaa
     8041 tggtccagtc ttgattgaaa gtgtaactta tcgctggctc ggtcactcat catctgaccc
     8101 tggtaaatat cgtacgcgtg aagaagtgga attgtggaaa caaaaagatc caatcgaaaa
     8161 cctccgcaat taccttattg aaaataacat tgcaagtgcc gaagaattgg aagaaatcca
     8221 agcgcaagta aaggaagcag tagaagcttc tgttaaattt gcagaggaaa gcccattccc
     8281 accgcttgaa tcagcctttg aagatattta cgcagactaa ggagaaagag ataaaatgga
     8341 aacaaaaaca atgtccttcc gtgacaccat tatccttgct atgtctgagg aaatgcgtcg
     8401 cgatgaaaat gtgttcttga tgggagaaga cgtcggtgtc ttcggaggag acttcggtac
     8461 ttctgttgga atgcttgaag aatttggtcc agaacgtgtc cgtgactgtc cgatttctga
     8521 agctgccatc tctggagcag cagcaggagc agccatgaca ggacttcgtc caatcgtcga
     8581 tatgaccttc atggacttct ctgttattgc catggacaat atcgtcaacc aagctgctaa
     8641 aacacgttac atgtttggtg gtaaaggtca ggttccaatg actgttcgtt gtgcagctgg
     8701 taacggagtt ggctctgccg cccagcactc acaatctcta gagtcttggt ttactcacat
     8761 tccaggactt aaggttgtgg cacctggaac acctgcggac atgaaaggcc tgcttaagtc
     8821 ttctatccgt gataacaacc cagttattat acttgagtac aagtcagaat ttaaccaaaa
     8881 aggggaagtg ccagttgatc cagactacac aattccactt ggggttggtg aaatcaaacg
     8941 ccaaggaacg gatgtaacag ttgttactta tggaaaaatg cttcgccgtg tggttcaagc
     9001 tgctgaagaa ttagcagaag aaggaatttc agttgaaatt gttgacccac gtacccttgt
     9061 tccgcttgat aaggatatca tcataaactc agtgaagaag actggtaagg ttgttctggt
     9121 caacgatgcc cacaaaacaa gtggctatat cggtgaaatt tcagctatta tttcagaatc
     9181 agaagcattt gactatctag atgcaccaat tcgccgttgt gcaggagaag atgtgccgat
     9241 gccttatgca caaaacctag aaaatgcaat gattccaaca gttgaaagta tcaaagatgc
     9301 aatccgaaaa acttataaca aagaataggg ttacataaga taagttatgt aaataaaata
     9361 aagctgacga gaaactttgt atcttttagg tgcagagctc ttcgtcatta atatcttaga
     9421 ttagagcacg ggctaaaaga tcggaaaaaa gataaatctc cttggcttca tcgaagccat
     9481 cgtcgatttc ctatttttca gtcgcttttg acgccctttg tatcataaat agaattggag
     9541 aggtcatggc tgatgacaag ctaagagcga ctcctgcagc tagaaagtta gcagatgatt
     9601 tagggataaa cctctacgac gtttctggct caggtgcaaa cggtcgtgtc cacaaagaag
     9661 acgtggaaac ttataaagac acaaacgtgg ttcgcatttc gccacttgca aaacgaattg
     9721 ccctcgaaca taacattgct tggcaggaaa tccaaggaac cggtcatcgt ggtaaaatca
     9781 tgaagaagga tgttttggcc ctgcttcctg aaaatatcga aaacgatagc atcaaatctc
     9841 ctgctcagat tgaaaaagtg gaagaagtcc ctgataacgt aacaccatat ggtgaaatcg
     9901 agcgtattcc aatgacacca atgcgtaagg ttattgccca acgcatggtt gaatcttact
     9961 tgactgcgcc aaccttcacc ctcaactatg aagttgatat gactgaaatg ttggctcttc
    10021 gtaagagggt tcttgagcca atcatggaag caactgggaa gaagactact gtaacagacc
    10081 ttctttcact tgcagttgtt aagactctta tgaaacatcc atacatcaac gcttcattga
    10141 cagaagatgg caagactatt atcactcaca actatgtcaa tcttgccatg gcagttggga
    10201 tggataatgg attgatgaca cctgttgttt acaatgctga gaagatgagt ctttcagaac
    10261 tggttgtagc ctttaaggat gttattggcc gtaccttgga tggtaaattg gctccaagtg
    10321 agttacaaaa ttcaacattc acaatcagta atttgggaat gtttggtgtt cagtcctttg
    10381 gtccgattat taaccaaccc aactcagcta tccttggtgt cagttcgaca atcgagaagc
    10441 cagttgtcgt caatggtgaa attgtgattc gcccaatcat gagtttagga ttaaccattg
    10501 accaccgtgt cgtagatggt atggctggtg ctaagtttat gaaggacttg aaagagttga
    10561 ttgaaacccc aatctcaatg ttgatttaag agcaagagta ttcattttta agatatagat
    10621 aaaggaagga agacatggcc ttagaagtaa ttatgccaaa agccggcgtg gatatgacag
    10681 aaggacaaat cgtccaatgg aataaaaaag tcggagaatt tgtaaaagaa ggagaaatcc
    10741 ttttggaaat catgactgat aaagtcagca tggaattgga agccgaagaa gatgggtact
    10801 tgattgccat tctcaaagga gatggtgaaa ctgtccctgt aacggaagtt atcggttacc
    10861 ttggtgaaga aagggaaaac atcccaacag ctggagcagc atcgccagaa gctagccctg
    10921 tacctgtagc aagtacctca aacgatgatg gtaagagcga tgatgctttt gatatcgttg
    10981 tgattggtgg aggtcctgct ggttatgttg cagccattaa agctgcccaa ctcggcggta
    11041 aggttgccct tgttgagaaa tctgaacttg gtggaacctg cttaaaccgt ggatgtattc
    11101 caaccaagac ctaccttcat aacgctgaaa ttattgaaaa tatcggtcat gctgcaaatc
    11161 gtggtatcgt gattgaaaat cctaacttca ctgttgatat ggaaaaactt ttagaaacta
    11221 aatctaaagt tgttaatact cttgttggtg gtgttgcagg acttcttcgt agctacggag
    11281 ttactgttca taaaggaatt ggtacaatca ctaaagacaa gaacgtcttg gtaaatggtt
    11341 ctgaattgct tgaaaccaag aaaatcattc ttgctggtgg ttcaaaagtc agcaagatca
    11401 acgtccctgg tatggaatct ccacttgtca tgactagtga tgacattctt gaaatgaacg
    11461 aagtgccaga aagccttgtt atcatcggtg gtggagttgt cggtatcgaa ctcggtcagg
    11521 ccttcatgac atttggttca aaagtgactg ttatcgaaat gatggaccgt atagttccag
    11581 ctatggatgt ggaagtttct aagaaccttc gcttgatcct tgagcgtaaa ggaatgacca
    11641 tcttgactgg tactaaactg caagaaatca ttgaggaaaa tggtcaactt cgtatcaagg
    11701 ttgaaggaaa agacgatatc atcgcaagca aagctcttct ttcaattggt cgtatgccag
    11761 accttgaagg tattggagag gttgagtttg aattggatcg tggttgtatc aaggtcaacg
    11821 aatacatgga aacttcagtt ccaggcattt atgcaccagg tgacatcaac ggtactaaga
    11881 tgttggctca cgcagctttc cgcatgggtg aagtttccgc tgaaaatgcc cttaaaggaa
    11941 atcatgcagt tgccaaattg aatttgactc ctgcagccat ctacactctc cctgaagtag
    12001 cagcagtagg tttgacagaa gaacaagccc gtgagaaata cgatgttgcc atcggtaagt
    12061 ttaactttgc tgctaacggt cgtgctattg catctgacgc agctcaaggt ttcgtaaaag
    12121 ttatcgctga taagaaatac ggagaaatcc ttggtgtaca cattattggt cctgcagccg
    12181 cagaattaat aaacgaagca tcaagcatca tcgaaatgga aatcactgtt gaggaaatgc
    12241 tgaagaccat ccacgggcac ccaacttact ctgaagtgat gtacgaagcg tttgcagatg
    12301 ttctaggaat ggccatccat tcacctaaga aaaaataaaa cgaagataga ttagactgga
    12361 aggttatttc cagtttctat catataaagt aaagggatat catgaaatac attatcaatc
    12421 attcaaatga cactgctttt aatattgcct tggaagaata cgcctttaaa caccttttgg
    12481 atgaggatca aatcttccta ctttggatta acaagccatc tatcattgtt ggtcgtcacc
    12541 agaacactat cgaagaaatc aaccgtgatt atgttcgcga aaatggtatt gaggtagttc
    12601 gccgtattag tggtggtgga gctgtttacc acgatttaaa taacctcaat tacacgatta
    12661 tctccaaaga agatgaaaat aaggcatttg acttcaagag cttctcaact ccggttatca
    12721 ataccctggc tcaacttggg gttaaagctg agttcacagg tcgtaatgac cttgagattg
    12781 atggtaagaa gttctgtggc aatgcccaag cctatatcaa cggccgtatc atgcaccacg
    12841 gttgcttgct ctttgacgtt gatttgtcag tcctcgcaaa tgcccttaag gtttcaaaag
    12901 ataaatttga atcaaaaggt gtgaaatccg tccgtgcccg tgtaaccaat attatcaatg
    12961 aattaccaaa aaaaatcaca gtcgaaaaat tccgtgattt actcttggaa tacatgaaaa
    13021 aagagtaccc agagatgact gaatacgtct tttcagaaga agaattggcc gaaatcaatc
    13081 gcatcaagga tactaagttt ggaacttggg actggaacta tggtaaatca cctgaattta
    13141 acgtccgtcg tggaatcaaa ttcactagtg gtaaggttga agtctttgct aacgttactg
    13201 aatcaaaaat ccaagacatc aagatttatg gtgacttctt tggtattgaa gacgttgctg
    13261 cagtagaaga tgtccttcgt ggggtgaaat acgaacgcga agatgttctt aaggcgctaa
    13321 aaaccattga tatcacacgc tacttcgctg gtattagccg tgaagaaatc gctgaagcgg
    13381 tagttggata aatcaaaaag aagttggcca actaaccaac ttcttttttt gatatttatt
    13441 tacataattt aaaatacgta aaatcataaa ctatccagag cattcttttg ttcatcatta
    13501 acaatatggg tatagaggtc agtgacttgt gtgctggcat gtcctagttg gtgactgact
    13561 aaaacttgtg atttagtagc atcatagagc ctagttgcta gtgtatggcg cagtttatgg
    13621 ggtgttacac gtactttaaa atcctctgag tatttagcaa ccattttctc aacgctagaa
    13681 gcatcgatac gattaggaac acctctgtag agagttaaaa aaagggctgt atctgttttt
    13741 tccgttttat agcgttgatt ccgaatggcc agataattct ctaaataagg tttagcaaaa
    13801 gcagcgacat tgactgagtc acgtttgcca ccttttcgag taacatcaat aaccatcatt
    13861 tttagattga gatctcttag atctagatta acagcttcag ataagcgaac accagatgcc
    13921 aagagaaggg caataatggc taaatctcgt tctttatttt tgttgaatga tgagagagct
    13981 cgatttgaaa gctgttgtgg gtgctcttga tcgatataag ttagaaaacc ttctgtttca
    14041 tcacctagaa agagtttttg cttgatattt tcagctctgg cagcaagggt ttctttcttt
    14101 ttcttggttg aaactttttt cattacatta cgatagaaat aaggttcccc ctgatcgttt
    14161 tcaacctcct cggttagata cttgtaaaga ctagaaagtg ctgataaggt tcgattgata
    14221 gttgtctgtg aaacaccttg ttttgttgta ttagcattca gcaagggacg ttcacgtaga
    14281 taaaggataa aggattccat gtctttctta gacatatttt ccaaaactga taaaggaata
    14341 tcggatattt tatcagcgtt tgaaatacca gactccaaaa cccagctgaa aaatcggtca
    14401 tattccttaa ggtattcgta cagggttgta aaactgtagg gcacagccag tttagattgg
    14461 tagtattcca gaacatacca gggcatgagt tgttttagtt tgtcgattcg ttccagtaaa
    14521 atctcacgtt tcatgtattt tctccataat taagtatact agtagtatag catagacttg
    14581 tgtatttttc aagaaaatta tagtttttca gaaagatgtt ataggagttt ttcaaagtga
    14641 taaaaagact tagacctaca aacaaaacag aataaggaaa ataataaaaa tctcacccac
    14701 taaacttctg ttaatactac ataactgaag agctatataa ggagctatga gatacaaaac
    14761 acattgtata atagattgaa actagaatag tacatctgga cttctaaaac attgctagaa
    14821 attgatttga ttgtcctgat tgttttatcc tatttctatt tcatttctct atataattgc
    14881 tattgttttc tttttcatga ttttaatctt actgtacaga tttgatacag taaactcctt
    14941 tctagcttta tactttatca tttctaactt aattatagtc ttatttttaa taaagttcaa
    15001 ttatttatat gtaaaattcc tcatcagtaa aaaataaccg atctcatttc tgagaatcgg
    15061 ttttctaaat aaatcaaacc gatcatttac ataacataaa ttatgtaaat gatcatacta
    15121 caacaacaaa tctttgactt ttccaatttc actttttgga ataaccaggt gaatcatatc
    15181 acccagatac attctggttg agccgttaac tgtttggctc ttgccattat ggacttgagt
    15241 tgtgatgagg acgttgtgtg gtaagttgag ttcatgaact tgtttcccag caattttatc
    15301 agaaactggt atttcgataa gtgtaacttc tccttcgcta gatacttctt ctggaagcat
    15361 tttttccagc atggcttcat agactggcgt acctttgagc aaatccatga taatataaga
    15421 aacaagagtg acaagaccaa gtggcataag gttgcgaata tctcctacca tctcagttac
    15481 gaggatcata gcggttaagg gagcttttga tatggctcca aaatagccac tcattcctag
    15541 aatgacaaat atagggaatt gctcttgact gacaagtcca agattgacac agataacacc
    15601 aactaaggca ccaagcaaag aaccaagagc taaaatgggg aggaaaattc ctcctggcag
    15661 tccacttcca tagctaatca tactccaaat aaagcggatt aaaaagtaag ctaataaaac
    15721 ttggaaacta aaattttgtt cagttaaaga aaggacaagc tgatttccgc caccaatgat
    15781 ttgaggtaag aagattccga ctggtatgat aaggataaaa gccaagatgg gataataagc
    15841 cctatccaaa tggatttttt gaccaatcaa gtcataaact cttccaacgt ttaatacagc
    15901 tttctcatag agaaaacctg aaaatccaag gaaaattccc atgacgagat atatccaata
    15961 ctggtctagg gtcatgggag gaatgttatc tggcatatcc aatactggtg tcaaaccgaa
    16021 catgagtaga gacacaaagt ttgctacgat gctggctgct agagttgaga cccagaaaaa
    16081 gcgcgaaaaa tggtgataga cttcttctac aacaaagaga agtgctgcaa taggagcatt
    16141 aaaggctgcg gctaaacctg ctgcagctcc actggcaatc aaggaacgtt cctctactgg
    16201 actggatttg agccacttgg caattccttt accaccaact gctccaagtt gaatgctggg
    16261 tccctctcga cccagcatga gtccactggc aatagcaaga atacctagca catatttttt
    16321 ccaaagaatg ccccaccagt tgagggacat gaggcctttc agttcggctt cgacttgagg
    16381 aattcctgag cctttaatat ctttttctga ccgtgttagt ttggcactga gccaacagat
    16441 gagtatataa aacaaaacca gtacaaaaag attgcgcact aagtaccctt gatcttgata
    16501 aactccttgt atcaggtgga agcccttttc aattaagaaa cgaaaggatc cgacgataat
    16561 tccaacgatg aggccgacaa tgattcctcg accaacttgg gatagtatag tgctggatgc
    16621 aaaggcgaat tctttcttag aacggactat ttccgactgt tcctccatgg tatttccttt
    16681 caattaactt tcttttttac ctaaaaccag tgatttaacg ggttcaaagc tggttcggtg
    16741 aattggggta actcctagtt ttgtgaggcc ttccagatgt ttagctgtgc catatcctgc
    16801 attagtagcg aaatcatagc cagagaactg ctgatcgtat tctttcatca attcatcacg
    16861 tgttaccttg gctactatag atgctgctgc gatagagagg gagttggcat ctcctttgat
    16921 aatggaggtt tgtgaaatgg gcaagtccag tttcatggca tcaatcaaaa ggtgctctgg
    16981 ttgagggctg agctgggaga ttgcttcttg catggctagt ttggttgctt catagatgtt
    17041 gacttggtcg atgacctgat tatctatgat accaattcca atcgacaagg cttggtcttg
    17101 aacggcttgg aaaatctcca gatgtttctt tttaggaatt ttcttgctgt cgttgagacc
    17161 tttaatctta caatttttag gtaaaataac ggccgcagcg actacaggac cagcaagagg
    17221 accacgacca acctcatcaa tacctgcaat taaggtcaat ccttgcttat aaagttcttt
    17281 ttcataagaa agcatggatt ccaagcgcaa attttcatct aattcagctt gaatggctct
    17341 tttacgcttg ctgatttcct tttgaactcc tgagcgatta tccttttcaa gctctaaaaa
    17401 aatagggctt tctaactcct tgactgtcac aaggagttct ttgatttctt taatcgttgc
    17461 catcgaggtc ttccaatgta tctaaggtat agttaccgag tttgccatca cggacttcct
    17521 tcacgaagag actgtaaaaa cggtcatagt catcacggaa accgagggcg cgggtcatat
    17581 ccataataat cacaggcgct tcttcttcaa ttttcatttg tttgaagcgt tcagccagct
    17641 tttctggata atgttctttg aaataattga taccaaaaat ggtaacctca tccataggaa
    17701 gcaactgatc cttgatagct ccagtcaatg ccaacttaag tgcaacagtt tcatcctcaa
    17761 acttaggcca gagaatcccc ggtgtatcca agatttccag atctttattg gttttaagcc
    17821 attgttgacc ttttgtgacc cctggcttgt ttccaacaac agcaatcttt ttaccagcca
    17881 aacggttcat cagagttgat ttaccagcgt ttggaatccc aataatcatg gtacgcaagg
    17941 tttcaatctg aatcccacgt tctttctggc gagcaatctt atcagccatg agcttcttgg
    18001 ccgcatctgt tacaactttt acagtcactt gctctttgga gttgatagct agcgtctgga
    18061 ttccttgtga ttcaaaatac tgacgccatt ccttggtcat tgctggatca gccaagtcgg
    18121 ccttgtttaa aatcaagagt tttggtttat caccaacaat cttggttaac ataggatttt
    18181 gactagatag aggcaagcgt gcatctacta aaatcgtcac aaaatcaaca aattttaaat
    18241 tttcctgcac ctgtcgacgc gctttagaca tgtgaccagg aaaccattga atagtagcca
    18301 ttgagttttt tcctttcgta gcaaggattt agatccccta ttttatttta ctatagtttg
    18361 aacatagaga gttttcaaat gaatgatgtc caaacagttc ttgttttatg acatagaaat
    18421 ctactttata ttatatcatg ccttctttat tttgtccgat gatagccttt taccctatct
    18481 tttagcctat cttttaccct atatagaaaa aagccatcaa atgatgactt ttcagaggga
    18541 gcaaaaaact gttcccgtca tattatgaac caaaagaact aaactaccaa cagctaatag
    18601 gcctaaagct gtaagctcag aagttgatga acctgttgca ggaagagttt cctgctgata
    18661 aataagagca taacttactt cattatcagt aggaattcct gcttgaatct tggtttgttc
    18721 ttcatcacct ttttaaactt tatttcctaa tagtaaacac tattttttat tctcaaaaat
    18781 tgaacttcta aaatcatttg tttggtcaag ataggcttta aagattgctc tcttcaactt
    18841 atgaacggca ctgtcgattt ctggatcata attactccaa cgtggacctt cagcatcctt
    18901 gagaacagct tggtccatga gggcttgcaa ttcatccaca ttattgatag tctttgtgcc
    18961 atagcttggc catggttttg tcggatcttt aaaggtcacc tgcttcaagt ttccaaactg
    19021 atccacccgt tcttggtaca tagctgtctt aaattctgcc caagttttat acttaccgtc
    19081 aaataccttt ttcaaaacaa gctcatcggt caccaagccc cgttctttac cataaagatt
    19141 gatagtttgc ccttgttgtt tagcatcttc ttcgtattgg tttgagatat aaggtaccat
    19201 tccatcctta aagcctttgg cagccaaaag ttcgtacgca atcctacgtc ccataaggtc
    19261 ccctggtgtg cctttctcac tgctgagagc tgaatagatt ggggcaaaga gtttgatggt
    19321 atagtagcca tttcgttcat agtcgccaga ctggtactca cgagctgata agatgttgtg
    19381 gtcaatcaaa ctttcaaaac tattcaggtt tcgggcctct gcttctgtca attctttgac
    19441 tacgttagtg gcataaacct catttccatc tgctggatct ttcacatact tgttctcaat
    19501 ttttctgaga gccgccattt tctggtaaac acttagttta ttaacgattg actgcccttc
    19561 gagatattcc atcatgtaga taaggtcaaa catgttatgg acatagttct gaagatctgc
    19621 tgcgttttgg aatctctctg tcggatccaa gacttgaaga cgggatccct ctgtactatc
    19681 tgattttgag tgtttcaaga tagaattaat ggtaatggtt gcgtcacttg gttggtcagg
    19741 ggcttgcaat aagccttttg cgaagaactc tggtcccaag ccatttcttc gaccatagcc
    19801 accaaggtaa atatcctgat ccgaatcatg ggtcatttca tgggtataag taatggctcc
    19861 atccttgtcc agcatgcggt aagacatata gtagacgctg tcccctgtag cgtaggctcc
    19921 atgctggttg tgtactacct tattgccaac tggtccaaag aagttcttca tagctggatt
    19981 ggagctatca aacttagcct ccgctgtagc ttttcctgat gttgtgtcat ccccaaactt
    20041 ataggcatca taaaggagaa tcgtacgata gagtttttcg cgtgactgtt catctaaaat
    20101 acgataccaa taatcgtagt gatctcgctg acgtttggct gtttcacgcg cattttcttc
    20161 aacaaaatca ttgagagcct tgcccgcttt atggtcacta ctgcggtagc gatcataagc
    20221 tccaaatcct agactagaca tggtcgagat gacaaatacg gatctctctg gcaaggtcag
    20281 gagaggcaag accatattgc ggtatttcca tgtggcactc gtgatacgat cataaacacc
    20341 gatagaatac ttggtgccag ctaacccttg cttcgttttc acctcttcga tagtggattt
    20401 ttcttcgaca atgtaagcct tagtctgtga tttaaaccag tcattattgc ttgtatttgg
    20461 taaaaagact tttcggtaat gttccagcgt gctaaacaaa tctgtcgctc catgttgact
    20521 ggcaagactg ataccataag tatcgacatt attcttagct agaagattgt taaagccaga
    20581 tttacctaac tcaatcagag tatctagtgg ggaagtattt cctttaccaa agaagtctgg
    20641 atgatacata actaggtctt tgacattcac ttgaccatag ttaaagttat accaacgttc
    20701 taaataagtt aaaccgagta gcaaggcttc cttattattc ttgattttat ctacaagata
    20761 gcctctggtg actgagttat cgctagctag accggcatct gctgtcaaaa gttttttcaa
    20821 gctgtctccc agattttgtt ttgttttgga gaactggtct tctaaataga gctcggttaa
    20881 cttaacttct ggagaaatac caagtgtctt tctgatagca tctgactggt aatcaagctt
    20941 ctgcaactca ggcaagactt ccttaacaat agagtctcga tcatataaga attggttagg
    21001 agtgtagaga agtcccgtat tacctagatt atattctgct agattggcaa aatcagtctg
    21061 gtacttgaga tcaaatttct cagatgaatg gtcattatag tgaagtaaga gtttgtttgc
    21121 agtctgtttg ttggaaacaa tatctgtgat tacttggtca tccttcatca taactgcaga
    21181 taagagttct ttttggtata agagactgtt ctccttaacc aggtttccgt atttgacgat
    21241 ggttgactta ttataaaaag gtaacaattt ttcaatgttc ttataaacca aagcacggtt
    21301 agcttgataa tgggctatct tagaaaaatc actgtctttc ttgccacttg ttgagagggg
    21361 ttccaccgtt ggtagagtga gaggatttat ttctgctttt ttgcttacaa tttgagaagc
    21421 atctagcatt gttcctcttt cttcaaagga ttccttgctg acgacctcat ccttctctaa
    21481 agtgacattg aaaactctat tagctttact actaaatgta ttagctacct tcattcctgt
    21541 atagtggtat ccagtgatgg catttccgtt tgttacattg acatcgctaa gaacattggt
    21601 caattcacca gcgtgttttt cctcaccaga agttcgatcc cacaaatatc ctgccacacc
    21661 agcgacttta ccaaagtgct tgacattatt aatatcacct tccgcataac tgttctgtat
    21721 atgcgcatct tggtctacta gacctgcaag accaccgaca gtctgatctg acctattggt
    21781 gtttgacgaa atggttactg tcgctttgga tttagcaata gacgcatttt ttcctgttaa
    21841 atgaccgacc agaccgccaa tattgtaggc atcagtcgtt tcataggtat tgacaattct
    21901 tcccttgaaa ctgctctctg cgatgcttga ttggtctgcc ttagccaaca aaccaccgac
    21961 accacgttct ccagccagaa caccatcaac atgaacttgt ttaatctttg tgccattcgt
    22021 agcttcattt gccagtgaac caatatcatt tttccctgaa atagcaacat tttttagact
    22081 cagtttttct actgtagcac cactcaagtt ttcaaacaga ggttttttca aattatagat
    22141 agcataattc ttgccatctt tttcaccgat taaacgacca gtaaaggtgt ccttgatata
    22201 ggatctttca tcaggaccaa gctccacttc gttagcattc aggctggccg ctaaatgata
    22261 ggttccagag ggattttggt ttatagcttt gaccaggttg ctaaaggaag taaagtttgt
    22321 attttcctct ttagccttct tatcgaggta gaaggtgaaa ttgtcgacat atttattttc
    22381 tagttcttgc tggagtttct cagctttggc tgtgatttta taaactgact gcccatttct
    22441 tttctcttcg gttattgaag ctactggtat atagacatct ttaaatgctg aagattttac
    22501 cttgacaaag taagtatccg tattctctgg aattccatcc aatgaaacat gttgtctgta
    22561 ggttccattc gtctgactat acaactcaat atcagaaaca tttcttaatt cgagtttttt
    22621 ctctggttct gtttgtccat tctctgatgt tgtattacct gaattttctg gttttgttgc
    22681 agttctgttt ttttctggtt tatttgattc tccaactgag gttgtcgaat cactaggatt
    22741 actggacact tccccagtat tttcgctaga tgtatctggt gatactttct ctgaattcgt
    22801 tgttgattct tctgcaggtt gaactggatt ttctgcttct tgaattgagg ttccttctgt
    22861 agtaccttca tttggattta ctggtgtttc ttctgttggt tttactggaa cttcttcagt
    22921 tttttctgga ccttgttctt tggtcttctc aaccggagtt tcaggtttta cttgctcaat
    22981 attaccctta tattctggca atggtgctac ctgctctggt tcccctttat cacttacaac
    23041 agcttcgggt aattcaggtt ggacagcggg ctcacctttg tcggtcacaa ctgcttcggg
    23101 taatgtaggt tgaacttctg gttcgccttt gtcacttact acagcttcgg gcaactcagg
    23161 ctgaattacg ggttcaacaa tagctccaga ctgtacgtcc ttatgttcta caccagtctc
    23221 aggttgttcc tttataactt gagttttttt agtacctttt tcgactattc ttggactagg
    23281 cgcagtcgtt gaagttgaaa caatttctcg cgaaacttct tccttgttta cagagaatat
    23341 tctgacgatt tcaactttct tacctaattt accttcttgt tttactctta cagttccttc
    23401 agctaaatca ggattttctt gaatttcttc ttgaaaatct atttttgtct ctatagtttc
    23461 ctcacgatat aagagttcag gtttgttcaa ttgacctgat aaaacttcat cctgtggatt
    23521 taatgtattt accccagtct tttcttttgg agaaatcttc tcctctttct tcgtttctag
    23581 attcttatgt tcggctaatt gttcttgaga atctgaagat tgtttctctt cttttcttgg
    23641 attgattaat tcagtagaga aaggtttttc aactacttga acttctgtcg gcttagttga
    23701 agaaacaggt gtttgttcct gaatagcttg tactgttgat ggatggtcta caaaatttgg
    23761 tgtaacatta taatccacct tttgttgttt tgtaggagtg gctgctgatt tttcttgatt
    23821 acttacttca aaatcagaag tcgtttttcc ctctttgata tatccaatat aagtgtaacc
    23881 tgaaatctct ttaggaagag gtaatttttc tccagaggtc aattcatagt ccgtattgta
    23941 atttagcaaa agatgatttt ctaaagcatg gactgaaact aagacaccat ttcctattcc
    24001 cgcaaccaat actaaatgta ataccgtttt attcttaacc tttttcttgg aaacagcaaa
    24061 aattaaaatt cccagagcag ctaagctagc accagcaact agggcttgcc tctcattctt
    24121 gcttccagta tttggtaatt ccgccagttg attttgagaa tttaacttat aaacaagata
    24181 ataagtttca tcatcattct ccacgtatgt cggaatatca tagacaagct gcttcttttc
    24241 ttctgatgat agctctgaat ctgccacata tttatagtga actcccgcag tttcttgagc
    24301 atccacagat gaactagcta atacagacat aaaaaataaa cttgaaatcg ttgcagatac
    24361 aagtcctact gataattttc taaatgaaaa acgctcttgt ttttcaccaa aatacttttc
    24421 cattattcct ccttgaaata aaatttatat atgttacaaa gacctttatt atattagtgt
    24481 attatctatt atctatagaa aaggcagtat accttaatta tactcttaat ttacaaaaaa
    24541 gtcttaaaat tgagatgcgc tttcatactt tgttttatat tatttggggg tacaataaca
    24601 cctaccatga aatttacacg gtaggtgtta ctcatatcac taatcgttct aaaaatggtt
    24661 tgaggcagtt gaggagaatt ccttctatcc agcttccttg tgctgatgag cgatggtctt
    24721 cctgcaggct tttttttaga aaatctcgga cttgttctgg tgcgatttca aattcaaagg
    24781 ctttcatttt atagaaaaag tcgatgagat gatctgacaa gtattcagtt gaaaagggta
    24841 cttcaccact ttttcgatat tctaataaga gtctagaaaa tcgagctttt tcttcaggaa
    24901 gctcacgaaa ataggaattg aggatccaag tctgcttctg ttttctttca attggatcct
    24961 gactggcaat tcgttggtct ttttccagct ctttttggta ttgtttggcc ttgatagctc
    25021 gttctgctct atttttacca aaaagaattt tttcccactt gcgttcttct tgagtcaggg
    25081 tctctgtaaa gccaaagtaa tcttgataag cacgctctgc gggtcccatg gctagaacca
    25141 gattgtctgc atattgcttg gcgattttat ccctcttctt gcgttctttc tctgcctgga
    25201 tacggagttc ttgttcgtag tcaattttct ccttgcctag cttgacaagg tagagttggt
    25261 catccgattt cccaagtaaa aagggtttga tacacttttc aaggacttct tccatccgag
    25321 cctttttctt tggttccgcc ttggtccaac ttcctccctg aaagacttct aggaaaagct
    25381 ggtagtctct ctcaggcgca aattgattgc cacgattggg tttgaaaaca cctttttccc
    25441 agagccattt tagaagtcgc tcgtcaaagt tacttttatt gaccttgatt ttttcctttt
    25501 tctgagcttt tctggttaga ttttcaacct ttctgagcag tttttcttcc tcttccaatt
    25561 gctggtcaag ggacaattga tgaaaatgac gaacacagtc gctaccaatt ggaaagaggc
    25621 gttggcctgt gacaccgtta aagagttcat aagcgtattt gatggcattt ccacagacac
    25681 aattgctacg gccgataccg ttaaaaataa aggaaacttc attccattcc ttggtagctt
    25741 gttcccaagt atccgctttc gaagcctgta aaactgcatc gtgcagggat tttctaactg
    25801 gaagtgtcat gaggtctcct ttctaatact caataaaaat caaagagcaa actagaaagc
    25861 tagccgcagt cagctcaaaa cactgttttg aggttgtgga tagaactgac gaagtcagta
    25921 accatatata cagcaaggcg aagctgacgt ggtttgaaga gattttcaaa gagtataagt
    25981 tatactttta caacttgaac ctcgtcttta ccgagtaaaa tcaagtattt ttcaatattt
    26041 tcaatcgaat aggctcgtga taaagcctct tcgtatagag ctaactgacc acgatagcgg
    26101 tctacgagtt gacttggttc atcatagcgg tctgtcttgt agtcgaacag aacaattttg
    26161 ttttcgtaaa gcagatagcc atcaaggata ccacggacaa caaagtcttc ctgactcttt
    26221 tggtctcgtt tgagcatgga gaaaggttgc tcgcgataaa gatggtcggt attagcaaga
    26281 atttcctgac cgagtactgt gtcaaagaaa gcaagaattt tatcaagatt gatcttgtct
    26341 ctgacagctt ggctagtttg aacttgtttg agtgtttctg ttaggctagc aagggttagt
    26401 tgctggctga ggtcaattct ctgcatgagt tcgtgagtag cactaccaat ctcagctcca
    26461 gttacctttt ctttggttga aaaatctggc aaatcgaagc tgattttctt gcctactgac
    26521 tgaccttgac cagcaatctc gacaccttcc atatccataa ctggttcgta gaatttcttg
    26581 atttgacttg gggtttgaac actaggaagt tcaatagctg cgcggtgaag agtattataa
    26641 acttccacct ccttcagcat ttccagagct tctttgatgg tatctgactg acgattgtct
    26701 gcttggaagc tatcttggag aggactcttg gtttccaact ctccgatagc ttctctggtc
    26761 aactgatctt cgccaataaa acgataacta aagttgagct tgtccttagt aaacacttta
    26821 ctgatagccc aaagccaatc ttggaaattc cgtgcttgca gtctagtatt gctatttagt
    26881 ttcccatttt tggctgctgg gtattccttg gattccagct tttcacgaga acccttgccg
    26941 acaagataga gctttttctc agcccgcgtc atagcaacat acagcaaacg catctgctca
    27001 gaatagcttg ctagctgtaa ttcctcttcg ttctgcctat aggtcagact aggaatggag
    27061 agtttgatgg ttttaggata gtggtcttct actgcccctg tctccatctt ggcaatatat
    27121 ttgacaccaa gaccattctg acgactgaga atgacttctg acatagagtc ttgcttgttg
    27181 aaatcttgat ccatattgag gataaagacg taaggaaact ccagcccttt actcttgtgg
    27241 atggtcatga gctctactgc atcttttggc ggtgcgacgg ccacgcttgc caaatcgtgc
    27301 tgggcttcta agacttggtc aatcatacga ataaaacgcg acaaaccttt gaaattgctc
    27361 ttttcaaatt gatcagcacg cagtgctagg gcatagagat tggcctgcct agcaggacca
    27421 ttcggcaaag ccccaacata gtcataataa aaacggtcgt tgtaaatctt ccaaatcaag
    27481 tcatagagag agtgggtttt ggcatacaag cgccaagaag ctaggatatc catgaattgc
    27541 tttagttttt cagctagagc tgtgtgaatc aagccttttt gactacttgc cattttttgt
    27601 gcattgacca gtttctcata gagattttcg tggactttat cctctgcttt ctgaagggac
    27661 aaacgtgcta gctcatcctc atcaaaacca aacattggag acttcataag ggcaaccaag
    27721 gcgtagtctt gcaggggatt gtgaatgaca cgaagagtgt ctagcatgac ttgcacttct
    27781 agggattgga gataattgtt ttgctctccg tcagttttga caggaatccc gtactcagac
    27841 agggcgagga gaatctggtc attacgactg cggctggagg tcagaagggc aatttcctta
    27901 aaggcaacac ctttttcctg atgaagtttc agaatctcct tgataactaa gcgcatttcg
    27961 cctgttagtt tcgtttctgt ttgactctct tcttcctcac ctgtatcgtc cttgtcgtag
    28021 aggagaaatt ctgccttgtt gtctggattg ggagtcagtt tggtattggc aaaaacaagc
    28081 tggtgcttgt tatcatagtt gatttcgccg acctcttggt ccatgagacg ttcaaagaca
    28141 tcattggttg ctgacagcac ttctgaacta ctacggaaat tttccttgag gagaatgagc
    28201 ttgccttctt gaggattttg cgcatagcgt tggaatttct cattgaaaat ctgcgggtct
    28261 gcctgacgga aacgatagat ggattgcttg atatctccca ccataaagcg attgtggcca
    28321 ttagacaaca attccagcat ccgttcttga atatggttgg tatcctgata ctcatcgacc
    28381 atgacttcat ggaagcgctc ctgataagac tcacgaactt gtgggaaatt ttctaaaatc
    28441 tcaatggtgt aatggctgat atcagcgaat tcaaaggcat tttcctgtcg ttttctctga
    28501 cgataagcct ctacaaaatc gctcatgaaa gattggaagg ttttagctag tttccaagtg
    28561 tctccatgat aacgttcttg atagtcgaga atcgctatct ggtctgataa ttgtcctagt
    28621 ttagtaaact ggatctttct ctcttcgttg taggcatcag ccaggggctt caaatcagcc
    28681 ttacggctgg cattagtcag agctcgaccg tttttctcct tagagatggc gacaacacgc
    28741 gcaagcactg cctgataaac ctgactatcg gactcctgat ttagggagcc aatttcatcc
    28801 agaattaact gaacattttc taaataggca gcctttgcaa actccttggt atcgttatcc
    28861 agatggtaac ggaaaaagct ttccaaatcc caaagggctt gtttgatttg ctcagtcagt
    28921 ttttcttttt cactggtaaa atcagctttc tcaaatcctt tgaggaaaga ttcactcagc
    28981 catttttgag gattactggt ggattggagg aagtcataga ttttatagac ctgctggcgc
    29041 agaccccgtt cgtccttgcc acgcccagca aagtttttca gcaaatgact aaaggtctct
    29101 ttctgtttac cttggtaatg cgcttcaaag acctcatgaa agacttcgtt ttcgagaaga
    29161 agttgctcgc tttggttttg taaaatacgg aaattaggtg caatatcaag cagataacca
    29221 tgtttgccaa ggaatttttg tgtgaaagag tccatggttc cgatggcagc gtttggtagg
    29281 tctgccaact ggcgtcccaa gtgttgtttg aggtcgacat catctgtttc ttggattttc
    29341 ttgctgattt ttttctctaa acgttcttta agttcatttg cagccttgac ggtaaaggtt
    29401 gagataaaga gttgagaaat ttcgacacca cgcgccaatt ggtccagaat gcgctctgcc
    29461 atgacaaagg tctttccaga accagccgat gctgagacca ggatattctg gccagaagtg
    29521 tagatagctt cgatttgttc ggcagttttc ttctgttcct tgctcgaatt tgcttctgct
    29581 tcttgcagtt tttgaatctc ctcctcactt aaaaagggaa taagcttcat cgattcaact
    29641 cctctcttat tttttcaagc caagcttgct tgagtttttc tccgaccaga cgcttgctat
    29701 cagctaggtc caactttttt aggaaacggg cttggcccag atggtaattg gcttcaaagc
    29761 ctgtaatagc ctgatgttgc tggacgtatg gggcaatgct tctgccattt tcagtataag
    29821 gattgatggc gaaccggcct gctaaaatct tctcagcagc tttcttgtaa agataggcat
    29881 tgtagtccag taggagctga aattcctcat ctgtcagttg attagccttg tttttgttat
    29941 aaaattcgcc taaataactg ctttcttttt ccaagaagag cccttggtat ttcatagatt
    30001 tgctggcttc taccactgct cctgcaagac tttttaccgc catcagagat tggacaggtt
    30061 cagccatttc caagtacatg gcgccgaaaa agttctgctc cccttctctt tttagagcag
    30121 caagataggt tggtaactga gaattgagcc cattaaagaa atgaggaaac tggaactgag
    30181 tcagactgga tttgtagtct actactccta tcgctccatt agctttcaaa cggtcaatcc
    30241 ggtccacctt gcctcgtaca aagacactgc gtccattgtc taattgaata aaggcttggt
    30301 cttttccacc aaaatttgct tcttctttga tggtttcgat ggctggattg tgtcggagaa
    30361 tatgtccagt cgtccgtgca acatcaagca aaacttcctt ggtaaactgg gcttccaaac
    30421 tttcttgata aatagcttca aattcgcgtt cttgactggt ttcttgaata gcttgttcta
    30481 gacgttggtc aaaggaatct tcattaggca actgtaaggc gcgttcaaag atacgatgta
    30541 agaaattccc gtgactacgg gcatcaggac gcaaacgtaa ttcctcctgc aagcctaaaa
    30601 cgtagcgtag gaaataactg tattcattgc gataaaactc tgtcaaaccc gacgtagaca
    30661 ggtaaaactc ctgtttggca ggatagagag cttgcaaggt gtccttggct aaggtcttgc
    30721 tgcttggact ggttgggata gctggatttt ccagaccttg ctgatctagt tttttaccta
    30781 tgacacgcga cagaaccttg acaaaagtca aatcttgctc agtatcgctc atctcaccct
    30841 gctggtgata ggcaaccaga ctagacaaaa gactgtgata ggaccccata tcctccttag
    30901 acagtccttt gtgattcatc ctcttctctc tccgcctaaa tccaaaatgg atcaactctt
    30961 gaagataggc agattcctta ctttcacttt cgttaaaaag gcttggagcc gacaagaaca
    31021 actgcttacg agcagaattg accaaggaaa gcatagtgta gcgatttttc ttgagatttt
    31081 cactgctggc aatcagtaat tgaacgcctt cttcggtcgc ttggtttagg ttttgccttt
    31141 cttcatctgt cagaagactg gtgttttgag aaatttttgg taaattgtcc tgagttagtc
    31201 caatagcata gacaaagtca gcagtcaatg gtgcaatcaa atcgtaactc tgcaccagaa
    31261 cagtgtccac tgttgctgga atggtacggt attgggacaa actcattcca gaatggagca
    31321 aggctaggaa gtcttccaga ctaacctgtg aaccagcaaa aacagtcgca aattgttcta
    31381 aaacatggca gaaagccttc caaacttcgg cttgtctttc ctgttctaca gcttccaaag
    31441 tggttgtcaa atcttgtaac tgcttggtca cagctccttc ttttagaaag acactccatt
    31501 tttgtaggag tttttcagcc ttttgttttc ggctggcaaa gagggtttca agaggtgcta
    31561 aaattctcag gcggaggaca ttcaaacgct caagattaaa ttttccatgg tgggatttgg
    31621 tgaaggtttg ctgaaaggct ggcaagccat tgataccaag atagcggata tattgctcaa
    31681 aagcatcaat atcagactga ctgaggtcag tatacaaatc agttctaaga agattaatca
    31741 aatcctcctg acgaaaacgg taacgtttta aagctaaaat agactcgaca aactgagtca
    31801 agggatgatg agccatggct tcgcttctac caagataaaa aggaatctga tactggtcaa
    31861 aaatggtttt gagagataac tggtaagaag ctacatcccc caagagaata cgaaaatgct
    31921 tgtagctcag gtctgagttc tcatgtaatt tctgacgaat actacgggct actagctcca
    31981 actcctcctt ttgcgtcaaa caagaccaga tttgtaaatt ttcacggtct ttctcatcga
    32041 catccaaagc gagttctgaa aagtcataag aagactccaa caaacgagag gccttgtcaa
    32101 aactatccat cttctcatga gtttgagaac agtcctgagc aggcgtttgg tatttagaag
    32161 ccagatgatg gagaaatttt acgctggctt ggtagagatt gccctcgcta aaaggactgg
    32221 tataggcttt cttactagca taagccccga taacaatctc aacacctttg ccgtgaagta
    32281 agtccacaac ccgctcttcc tcagcagaaa aacgagtaaa gccgtcaatg accaaggcga
    32341 tttgattaaa atcactactt accttgtcat tctcaatagc ctcaatcaaa tgggacaact
    32401 gacttccctg ggctaactga ccttgattaa gataggctgt tactttctca aaaatcaaga
    32461 gtaaatccgc cctcttatcc tcatctgtta aattctccaa gtccaaaaaa ctcatctgag
    32521 atttggtcat ctcatggtaa agctcaatta actgctggat caattgagga tcctgcttaa
    32581 tagcgccata aacacgcaag tccttgggat cgagttcggc aaggcatttg taaaaggcca
    32641 acccaagacc gatatcatca agagtagttt tagctggtaa atcattcaag accagatagc
    32701 gagccatttg agcaaagcgc gtgacggtaa tcgaaaaaga agcctgctgg gacaagtatt
    32761 ccagcacggc gcgttccttt tcaaaagaaa gagagttggg ggcaatgtag aagacccgct
    32821 tgccagctgc aactagctct tctgcctctc ttgttagaat ttctgtcaaa gaagtccgaa
    32881 tatcagtata aagtaatttc atctcagcct cgttggaatt tttcatcacc ctatattata
    32941 ccatgattag cctcgtaaat ctgttaaaat atttaggcca tcctttcttt tcttcatcat
    33001 ctgctaaatc ttaaatactt agctttactt gtattagata gaataagtct ggctactgaa
    33061 aatcacataa taaaaaagcc tcggtaacaa ggctttgagt tttatgattg tttcttaggt
    33121 acggaataca cttcaatgtg ttgtcccagt atcttaatgt cgacgggtag attgtctgat
    33181 ttatcgccat caacatcgga ctctaattcg atatcagaag aagttttaat attacgtgcc
    33241 tttatatatt caatattctt gatagaatga ttgaactata gtaaattgaa actataacag
    33301 tacaccgtgg atgctaaaat atttctagaa attaatttga tttccctaat caagctgttc
    33361 gtatcttatt tcaatctaat atagtaaaat gaaccaaaaa tag
//
LOCUS       DAVHBD010000023        33141 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000023 DAVHBD010000000
VERSION     DAVHBD010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.023"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            129..1622
                     /locus_tag="VVK04_001142"
     CDS             129..1622
                     /locus_tag="VVK04_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU3989804.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..2552
                     /locus_tag="VVK04_001143"
     CDS             1635..2552
                     /locus_tag="VVK04_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU3989805.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNHNWQSKNLWKNLKL"
     gene            2644..2880
                     /locus_tag="VVK04_001144"
     CDS             2644..2880
                     /locus_tag="VVK04_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU3989806.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            2877..3290
                     /locus_tag="VVK04_001145"
     CDS             2877..3290
                     /locus_tag="VVK04_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU3989807.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            3408..4373
                     /locus_tag="VVK04_001146"
     CDS             3408..4373
                     /locus_tag="VVK04_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU3989808.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            4407..5429
                     /locus_tag="VVK04_001147"
     CDS             4407..5429
                     /locus_tag="VVK04_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU3989809.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWRGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAYG
                     GNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLVF
                     LLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVALVDKSKSEIY
                     YPCFKE"
     gene            5407..5628
                     /locus_tag="VVK04_001148"
     CDS             5407..5628
                     /locus_tag="VVK04_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU3989810.1"
                     /translation="MIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQNEFA
                     DFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            5658..9008
                     /locus_tag="VVK04_001149"
     CDS             5658..9008
                     /locus_tag="VVK04_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU3989811.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILSIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRARMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            9252..9353
                     /locus_tag="VVK04_001150"
                     /pseudo
     CDS             9252..9353
                     /locus_tag="VVK04_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9596..10066)
                     /locus_tag="VVK04_001151"
     CDS             complement(9596..10066)
                     /locus_tag="VVK04_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU3989812.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(10083..12356)
                     /locus_tag="VVK04_001152"
     CDS             complement(10083..12356)
                     /locus_tag="VVK04_001152"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU3989813.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQIFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQNKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            12703..15804
                     /locus_tag="VVK04_001153"
     CDS             12703..15804
                     /locus_tag="VVK04_001153"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU3989814.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVSYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRVSFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            15887..16894
                     /gene="pfkA"
                     /locus_tag="VVK04_001154"
     CDS             15887..16894
                     /gene="pfkA"
                     /locus_tag="VVK04_001154"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU3989815.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            16953..18458
                     /gene="pyk"
                     /locus_tag="VVK04_001155"
     CDS             16953..18458
                     /gene="pyk"
                     /locus_tag="VVK04_001155"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU3989816.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(19192..19417)
                     /locus_tag="VVK04_001156"
                     /pseudo
     CDS             complement(19192..19417)
                     /locus_tag="VVK04_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            20265..21137
                     /locus_tag="VVK04_001157"
     CDS             20265..21137
                     /locus_tag="VVK04_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU3989817.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQYATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGKGL
                     AKPFIMDNDKWVKL"
     gene            complement(21283..21627)
                     /locus_tag="VVK04_001158"
                     /pseudo
     CDS             complement(21283..21627)
                     /locus_tag="VVK04_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            21770..22081
                     /locus_tag="VVK04_001159"
     CDS             21770..22081
                     /locus_tag="VVK04_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989818.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            22085..22801
                     /locus_tag="VVK04_001160"
     CDS             22085..22801
                     /locus_tag="VVK04_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU3989819.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(22931..23746)
                     /locus_tag="VVK04_001161"
     CDS             complement(22931..23746)
                     /locus_tag="VVK04_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU3989820.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(23743..24648)
                     /locus_tag="VVK04_001162"
     CDS             complement(23743..24648)
                     /locus_tag="VVK04_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU3989821.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(24978..25061)
                     /locus_tag="VVK04_001163"
                     /pseudo
     CDS             complement(24978..25061)
                     /locus_tag="VVK04_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            25105..27234
                     /locus_tag="VVK04_001164"
     CDS             25105..27234
                     /locus_tag="VVK04_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU3989822.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            27221..27670
                     /locus_tag="VVK04_001165"
     CDS             27221..27670
                     /locus_tag="VVK04_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU3989823.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            27729..28001
                     /locus_tag="VVK04_001166"
     CDS             27729..28001
                     /locus_tag="VVK04_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU3989824.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(28337..28528)
                     /locus_tag="VVK04_001167"
     CDS             complement(28337..28528)
                     /locus_tag="VVK04_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989825.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            28956..29714
                     /locus_tag="VVK04_001168"
     CDS             28956..29714
                     /locus_tag="VVK04_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989826.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            29716..31704
                     /locus_tag="VVK04_001169"
     CDS             29716..31704
                     /locus_tag="VVK04_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989827.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFVKNDGLKGQKTLTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(31746..32390)
                     /locus_tag="VVK04_001170"
     CDS             complement(31746..32390)
                     /locus_tag="VVK04_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU3989828.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFNI"
     gene            complement(32362..>33141)
                     /locus_tag="VVK04_001171"
     CDS             complement(32362..>33141)
                     /locus_tag="VVK04_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU3989829.1"
                     /translation="GTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKE
                     KILHYHNQKFSPDKKQASTNFKPAGQSIEQRSEAINLRLENGHYEIDTVLLTRAKNYC
                     LLVLTDRKSRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSE
                     EHIYYAHPYASWERGTNENHNRLIHRWLPKGTKKMTPKEVAFIEKWINNYPKKCLNYK
                     SPREDFLMANLNLKFSVRNKSRNRFKFCRSFKYPARRCSWC"
BASE COUNT        10437 a         5741 c         6935 g        10028 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagttgtgg gaaattcttt
      181 ggacagaagg aaatgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtt gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgttt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaagtcata ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attggaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta aaaaaaggca
     1681 agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt caaatagatg
     1741 atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact gaagcactcc
     1801 cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt tatggattat
     1861 cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac aaagaaaaaa
     1921 ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta cgagatcatt
     1981 caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta caattagaat
     2041 tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt aaaaggctta
     2101 ttactaaaag aaaattgcag ttagatgaac taaacttgct cgtcaaatcc cgatttaacg
     2161 agatgtttgg ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg
     2221 gtgatagggg caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat
     2281 ttttaaatac aaagaatgtt actaaaaacg gattttcatt cgatacaaag caatttatca
     2341 ctaaaacaaa ggataaatta cttcgaaaag gcaaacttga gcgttatgat atagtcttga
     2401 caacaagagg tactgttgga aatgtagcgt actacgatga attaataaaa tataaacatt
     2461 tacgtataaa ttcaggtatg gtaatattac gtcccaagac accaaatcac aattggcaat
     2521 ccaaaaatct ctggaagaac ttgaaacttt gaagaaatct ctgatgcagg agtattttgg
     2581 ctgatattct gccattgtaa ttacggtaat gatttgttat aatacttcaa aggaggaaat
     2641 cagatggtag taaaaacaag aaaacaagga aattcaatca ccattacgat tccaagtgaa
     2701 tttaatattc caagtggtgt taaatacgaa gcgaaattgt taccaagtgg tgagattatc
     2761 tttactcctg aagaattggg gcagcaggtt tcttatgtat ctgatgatgc ctttgactta
     2821 aatttagata aaatatttga cgaatacgac gatgttttca aagctttggt ggaaaaatga
     2881 caatctatct gacagaaaag caaattgaaa aaataaatgc tttagcaatt caacggtatt
     2941 ctccaaatga gaaaattcaa acagttagtt cttctgcctt aaatatgatt gtgaacttac
     3001 cagaacaatt tgtctttggg aagtctcttt atccaacaat ttttgataaa gcaacgatac
     3061 tatttgtcca attgataaag aagcatgttt ttgctaatgc taataaaaga actgctttct
     3121 tcgttttggt caaattttta caattaaacg gctatcgttt ttctgtaacg gtagaagaag
     3181 cagtaaaaat gtgtgtaacc atcgcagtag aagctttaac tgatgaaaaa atgacaagct
     3241 actccaaatg ggtttctgaa cattctgtta gagaaaaggt caaaaagtaa cctagtatgc
     3301 tggatttgaa tgagcacaag aaaataaatg aacagacaat attagaattc tgtaatgcag
     3361 aaactgatat tgtctctttt tattgatgaa taagaaagtg agaaattatg gaatcaaaag
     3421 ttacaattat catgcaagaa atgttacctc ttttaaataa tgaacaatta ctagcgttga
     3481 gagagagttt agaacatcat ctagtagacg gaaaaaagca gcagaagtat tcgaataata
     3541 acctgttgca actatttatt accgccaagc aggtagaggg ctgtagctca aaaacaattc
     3601 gttattacca gaggacgatt gaaaacttgt ttaatgctat taaagagtct gtgacacaac
     3661 tcacaacaga tgatttaagg agttatttag caaattacca gtctgaaaag gattgtagta
     3721 aggcaaattt agacaatatt aggcgtatat tgtcttcttt ttttgcttgg cttgagcaag
     3781 aggaatatat cattaaaaat cccattcgac ggataaagaa aattaagact gagcaaaatg
     3841 tgaaggaaac ttatactgat gaacatttgg aaattatgcg tgataactgt gaaaatttga
     3901 gagatttggc aataatagac ctactagcat cgacaggtat gcgtgtaggg gagcttgtac
     3961 agttgaatcg ttcagatatt gattttgaaa acagagagtg tgttgtcttt ggtaaaggaa
     4021 agaaggagag accagtatat tttgacgctc ggacgaaaat tcatttaaga aattatctta
     4081 acgacagaaa agatagtcac cctgctcttt ttgtaacgct agttggaaaa gcccagagac
     4141 ttggaattgc tggtgtagag attcgcttaa gaaagttagg agacaaactc ggcatacaaa
     4201 aggttcaccc acataagttc agaagaactt tagcgactaa ggcaattgat aaaggtatgc
     4261 ctatcgaaca agtccaaaaa ctgctaggtc atagcaagat tgacacaacc ctggcctatg
     4321 ccatggtcaa tcaaaataat gtcaagcatt cacaccaaaa attcatctct taaaagcaaa
     4381 tcccgatatt ccgaggaggt ggttgcatga agaaagtgaa attaggtgaa gtggctactt
     4441 ttatcaatgg ctatgctttt aaacctcaag attggtcatc tgaagggaaa gagattatca
     4501 gaatacagaa tctgactaaa acttcaacag agataaatta ttattcgggt acgattgata
     4561 aaaaatacat tgttgaagct ggtgatattc ttatttcgtg gtcgggtaca ttaggggttt
     4621 ttcagtggcg tggaagatcc gcagtgttaa atcagcacat ttttaaagtg gtttttgata
     4681 agatagatat agataaatcg tattttaaat atgttgttga aaaaggttta caagatgctg
     4741 taaaacatac tcatggttcc acaatgaaac atttaactaa aaaatatttt gataatatta
     4801 tagttccata tacaaatttg ggagagcaac aaagaattgc aagtgagctg gatttgttaa
     4861 gcaagctgat tttaaggaga caagaacaac ttgaagagct taatctactt gtaaaatccc
     4921 gatttaacga gatgtttggg gatcctttaa ataataacaa gaaatttgca gtaaaaacgg
     4981 gacaacagtg ttttaaattt tcaagtggaa aatttcttga taaacatgat agagtttttg
     5041 aaggttatcc tgcctatggt ggaaatggca ttgcttggaa aagtcgaaaa tatttaattg
     5101 ataatcctac tatcatcatt ggtcgtgtag gtgcatattg tggtaatgta agaactaccc
     5161 acggtaaggt atggataagt gacaatgcta tatatataaa agaatttaag aattccgatt
     5221 tcaatcttgt atttttatta gaattaatga aagtaattga ttttagtaaa tttgctgatt
     5281 tctcaggtca accaaagata actcaaaaac cattagaaaa tcagaaatat atcctccccc
     5341 cactagccct ccaaaatgag ttcgcagact ttgtagccct ggtcgacaaa tctaaatcag
     5401 aaatttatta tccatgtttt aaggaataat aattatagtc gagtgatatc aggaagtgct
     5461 cagcctcagt taccaattac aaaattaaaa aaaatacttc tccccctccc cccactagcc
     5521 ctccaaaatg agttcgcaga ctttgtagtc caggtcgaca aatcacaatt tgcttgtgag
     5581 atagctataa aagtgtggag aaatagcttg aaatttagta taatatagct aaactatttg
     5641 tttaaagtga gaaaaaaatg ggaaatttta gctttctttt aaaaaatgac gaatatgaat
     5701 ctttttcaaa accttgcatt gaagctgaaa atatgattgc tacatcaact gtggctactg
     5761 cctttatggc gcgtcgtgct ttggagcagg ctgtccattg gatatatagt cacgattcat
     5821 atttagaagc tccctatcgt gctactctat cttctttagt atgggatgat gattttaggg
     5881 atatcgtaga ttctgaactc cacaagcaga tagttctgtt gattcggtgg ggaaaccatg
     5941 ctgctcatgg tggtgaaatt aaggaacgag aagcgatttt agctttacat catttgtatc
     6001 agtttgttaa ttttatcgat tattgttaca gcaatgagtt tgtggagcgt tattttgatg
     6061 agaagtgctt accactttca gcaaacatca aataccgaga aactccacaa tctatgataa
     6121 agttacaaga cagtttacca gaactgcctg attttcatga acagatggct gctcagtccg
     6181 tagaagttca agagacttat actgaaaaac gtgagactgc agcgcaacgg caagatgtgc
     6241 ctttccatat tgatcaatta tctgaggcag agacaagaaa gctctttatt gatatcgatc
     6301 tccgtttagc aggatggata tttgaagaaa actgtcgtgt tgagatagcc gttgatggtc
     6361 tcaagcacgg ttcaggaatt ggttactgtg actatgtact ttatggtaaa aatgggaaaa
     6421 ttttatcgat tgtggaggct aaaaaagcct ctgtcaatcc agaagtaggg gaagtacagg
     6481 tcaaagaata tgctgaagct ttggagaaac atatcggcta tcagccaatt tgctttatta
     6541 caaatgggtt gaagcactat atacttgatg gtccgaaccg ccgccagatt gcaggctttt
     6601 actctcaaga agaattgcaa ttagtgatgg atagacgtca tcttcaaaaa ccgcttgagg
     6661 atatttctag taaaattagg gacgatattt ccgggcgtca ctaccaaaaa catgccattg
     6721 caagcgtttg tgaagctttc tctaatcatc gtagacaggc acttttggtt atggcaactg
     6781 gggcggggaa aactcgtaca gcagtttctc tagttgatat cttatcacgt cataactggg
     6841 taaaaaacgt tctcttctta gccgatagaa cttccttggt taagcaagcc tatgattcgt
     6901 ttagaaaatt actcccagat ctttccgttt gtaacttctt agaagataaa gaaggagctc
     6961 aatcaagtcg tatggtcttt tcaacttatc cgaccatgat tggagcgatt agtggtcaag
     7021 aagaagtaaa tcaacgccct tttactgttg ggcattttga ccttatcata attgacgaat
     7081 ctcaccgttc tatttatcag aaatacaagt ccatttttga ttattttgat gcaagaattg
     7141 taggcttaac agctactccg cgtcaagatt tagataaaaa cacctatgga ttctttaatt
     7201 tggagaatgg ggttccaaca tatgcatatg atttggaaga ggctgttaaa gacggatatt
     7261 tagtagccta tcattctatc gaaaccaaac tgaaactacc tacggatggt ctacattatg
     7321 atgatttgtc cgaagaagaa aaggaacatt ttgatagcaa atttgaagac gatagctgtg
     7381 aaaaagatat tgatgggagt gtatttaatt cctttatttt caataaaagt acagtagaaa
     7441 ttgttttaaa tgaactcatg acaagaggaa ttcagacagc ctcgggtgat gaaattggta
     7501 aaactattat ttttgctaaa aatcatgacc atgcggaata tatcagaggt atttttaaca
     7561 accgctatcc tgaaaaaggg agcgactatg ctcaggtgat tgattatagt attaagcatt
     7621 atcagacctt gattgatgat tttaaaatta aggagaagta tcctcaaatt gcgatttctg
     7681 tcgatatgtt agatacaggt attgatgtac cagaggttgt taatttagtc ttcttcaaga
     7741 aagtacgctc taaaactaag ttttggcaga tgattggtcg aggaacccgt ctgtgtaaag
     7801 atttatttgg acctgagcag gataaggaaa acttcttggt atttgattat ggggacaatt
     7861 ttgattattt tcgtgcagat ccaagagatg gagagggtcg tcacattgtt tcgttgactc
     7921 agcgtttatt taatatcaaa gtggacttga ttcgagaact tcagggactc caataccaag
     7981 aagatcagtt tgcgagagca taccgtcagc agcttgtctc ggaacttcaa ggtcgtatag
     8041 agagcttaaa tgagttggac ttcagggctc gtatggtttt agatacagtt tatagctata
     8101 ggaaattgga aagttggcag aatctaactg ctgttacaag tgaaaccatt caaaaaaatc
     8161 tctctccgct tttatttgat gaagataaag aagatgagat ggcgaggaga tttgatttgt
     8221 ggttgcttca tattcagttg gggcaactga cagctaaatc ttccactgtt catatttccc
     8281 aagtgatgaa gacggctaga gctctttctg ctattggcaa tatcccgcag gtttttgagc
     8341 aggctgaaat tatcaggaaa gtacaggagc ctgaattttg gaaagaagtt aacttgtctg
     8401 atttggaaaa aattcgtctt gctattcgag atttattaca gtttttggat aaaacagacc
     8461 gtaaacccta ctatgttaac tttgaagatc gtatactctc cactgttcac gagaccacag
     8521 catttttgca ggtcaacgat cttcggtctt acaatgaaaa agttgagcat tatttgaaaa
     8581 ctcatctgga tgaggagtcc atttctaagc tataccataa taaaaagttg acatctgatg
     8641 atatgcttgc acttgaaaaa ttgctttggg aaaaattagg tagtaaagca gactaccaaa
     8701 gtcattatga aaataaggca attccgagat tggttcgtga gattattggc ttagatagag
     8761 agtctgccaa tcgtattttt tctaaatttt tgtcggatga gaatcttaat gccaggcaga
     8821 tttcatttgt aaaattgatt gtagactaca ttgtagaaaa tggtttttta gagacgaaag
     8881 tgttaacgca agagccgttt aaatcttatg gttctgttca actactcttc caacaccaac
     8941 taccagtact tcgtaatatt gttcaaatca ttgaacttat caataatcga gctggagaag
     9001 cggcttaaat tctaaagtga ttgccatgct gagactcatt taaaattaaa aagagtagaa
     9061 atttatgcta tatatgagaa gttttattag gaagaatgtc atcgtttttc tagaatacag
     9121 tatcagttgt taagtggctg ataaatttca aagtagatac ttgtaccacg atgtttgttg
     9181 atagagttat taacaaaaga gctactttga ttttaaagaa atagaaaaca aaaagccgag
     9241 caagaattca attgcaggag aaaatgaaat aatactcaat gaaaatcaaa gagcaaacta
     9301 ggaaactagc tgcaggctgc tcaaaacact gttttgaggt tgtagataag actgacgaag
     9361 tcagctcaaa acatggtttt gaggttgtag atgaaactga cgaagtcagt aaccatatat
     9421 acggcaaggc gacgttgacg cggattgaag agattttcga agagtataaa tcttcttagg
     9481 ataaagcaaa acgcatagta tcaagggttt tcaacacttg atactatgcg ttttctgatg
     9541 ttaaagactt tctaccaggt tttttaaaag cataattgtt agttgtagtc atttattatt
     9601 cttcaaagaa aaatggtggg gcgaattttt tcagttcttc aaagcacttt tgagcagtat
     9661 ctgcatcttc acagatgata agacagacat cattaccaca aagggtagcg atagcgtcag
     9721 ggaagctcaa agtatcaatg atagaaccaa aggattgagc cagtccagga agggttttta
     9781 gtaggacttg gtgttgaact gggcgcatcc agacaagggc gtcttccatg tagagttcga
     9841 gacgtttttc ccattttgag atggaaccat tgttaagaac ataataagcg ctatcttctt
     9901 cgcggacttt tgataggttc atatttttga tgtcgcgtga gagggttgcc tgggttactt
     9961 gaatgtcgtt ctcagcaaga agggcttgca actcagcctg tgtatgaatc ttgttttttg
    10021 tgataagagc gcgtataagt tggtggcggt gttctgattt attcataata atgtaactcc
    10081 ttttagcaag gtaaggtaag catggactga gcgaggtcga cagtcaagtg gtagtctgta
    10141 ttgtcacgga tggtgatttc aaagtcagta gtatagagga ctaaacggag agtgtctcct
    10201 tcttttagct tgtaaatagt tggctgcagt tcaaattgaa cgtccatcca ttcatctgca
    10261 gtaatatcct ctactaacag taaatcattt ctattttgta aattaaggta accttttgtc
    10321 acgactcgtt gtgcctctgg tctaaatggc aattcacaga gattttccaa catgtgatag
    10381 cgaccgttgt caatggttct agcacttaaa atagctggat aaggttgtag gtatttattt
    10441 tgcccaaatt ctagcagttg ggcagataag agccccttgt ttgtactgga tttgatacga
    10501 agattgagct gagcgcgacc gtttaggtgg agatctttag tcacaggaag gttaatagta
    10561 atctgattag ctttcccttg atagagctct gtattgaaga tttggtatgt cttaccatag
    10621 cgctcaaaat ccttatctgg gtactggttt tgaatagctt gctcttcttg accaagtgag
    10681 aaggtttcac agttttcttg cccaccgaag ttatcaagtg ataaccaagt ctgtggagct
    10741 gtattgtcct gccagataac agtaggaagt tgaaagtctg tttcctgtcc tagtaatttc
    10801 ttggtcaata aggcatttat ggactcacgg aagtcaattg attgccaatt gttcatgtaa
    10861 acatgggcac cattatggaa aaagagatgc ttgtgtatat gagtaggaag agcatggaac
    10921 atctggtaaa catgaagtgg tttgacattc caatcctgag aaccatgagt aaagacaacc
    10981 tctgccttta ctttatgggc attgagcaga taattgcggt catgccaaaa ctgattgtag
    11041 tccccagttt ttcggtctag ctgagctttc actttttcta agtcagcttg gtgagcttca
    11101 ttgccacgga tatagtcgcc agctaagaga ttacgagaat aggttaactc agcaagggag
    11161 tcaaagtcct cacctggata accacctggg ctagtcacca gaccgttttc acggtagtag
    11221 ttgtaccatg atgaaattcc tgcctcggca atgataactt ctaaaccatc gactcctgta
    11281 gtcgcaagac cattggacat ggtacctaga taggaaagtc ctgttgtagc aacttttccg
    11341 tttgaccaat cagccttgac ttgacgctgg cgcgtgtgat cagtaaaggc acggcaacgg
    11401 ccgttaagcc aatcgatgac atttttataa gcctcgattt gctggtagtc tccattagtc
    11461 atgaaacctg tcgagtcttt ggtaccaaca cctgagacat agagattggc aaagcctctc
    11521 ggaaggaagt agtcgtttag tgtatagcta gagttgatgt gagttagctt ttcctcagcc
    11581 tctgctataa gctcagcttt accttggggt tggacgagat ttagttgagg tttctctagc
    11641 tcaatcttgt gaggaagttt aacctcaagc tcgccctcca tcttgtagag agccttgtca
    11701 ctagccttgt cattggttcc ctgatgataa gggctggctg tcatgatggc agggattttt
    11761 ccatcaaaac gagggcgaat aatgctaacc tttactaggt ctgatagccc tttttggtca
    11821 gtatcgacac gagactcaac gtaaacgact tcacgaatga catcctggtt agaaaaagta
    11881 gccaaactct tgccgttaaa gtagtggtag tcattatcct ccggaataag accatcacta
    11941 acaagttggt cgataagagt atttcctttt ttggtgcgag tattgagtaa ctgatagaga
    12001 ttttcaatca agtcaccata tataatggga aatccagttt ctttacgaaa aacgtcacta
    12061 tcttcgaagt caaccaaata agaaaagcct aaaagttgaa aagcaacagt ataaaaaata
    12121 tctgctgtca gttcatcttc tgattgaaaa aatgtcagca ggtctgtttt tttatcagct
    12181 gctaggatag aaagtgggta gttggtgtct tgataagtga aaaagaaacg acgtaaaaag
    12241 gtttcaagtg agtctttgtg attggctgta ttttgtaaat caaagccaca tttttttagt
    12301 tcagataaga cattttcttt tggaaaattg atataactat attgattaaa acgcatagaa
    12361 cctccatata gaatgacagt taaggttatt atatcaaaaa aaaagcagaa agggaattgt
    12421 taacttcaaa aggaaataat ccaataaaaa tgaataaagt actaaattca atatagagaa
    12481 cagagtaaca ataagaataa atagataggg tataaaagtt ctaggagatt tatattatat
    12541 gctttctatt tttatataca atatagtata aatataaaaa tgatgacaaa aatacaaatg
    12601 aatagaaaat aaattagtaa gctgatgaaa tttttctcaa gagaagccat ttataggtga
    12661 aaatggtata atatagtgag aaggatagag gagaagtgta aattgatcgc acaactagat
    12721 acaaaaacag tctatagttt tatggaaagc gtcatttcga tcgaaaagta tgtgagagca
    12781 gctaaagaat acggctacac tcatttggct atgatggata ttgacaatct ttatggcgct
    12841 ttcgactttc tagagattac aaaaaaatac ggcattcatc ctttgctagg gcttgaaatg
    12901 acagtgtttg tagatgatca ggaagtgaat ttgcgctttt tagctctatc tagtgtgggc
    12961 tatcagcagt tgatgaagct ttcgacagcc aagatgcagg gggagaaaac ttggtcagtc
    13021 ctgtcccagt acctggagga tatcgcggtc attgtgtctt attttgatag agttgagtcg
    13081 ttagaactag gctgtgatta ctatataggg gtttatccag aaacactagc aagcgaattt
    13141 catcatccta tcttacctct ttatcgggtc aacgcttttg aaagcaggga tagagaagtt
    13201 cttcaagttt taacagcgat taaagaaaat ctaccgctca gagaagttcc cttgcgttcg
    13261 agacaagatg tctttatatc agcaagttct ttagagaaac tattccaaga gcgttttccg
    13321 caagctttgg acaatttaga aaagcttatt tcaggcattt cttacgactt ggatactagt
    13381 ctgaaactgc ctcgttttaa tccagctaga ccagcagtag aggagttgag agagcgtgct
    13441 gaactggggc ttgttcagaa ggggttgact agtaaagaat atcaagatag actagaccaa
    13501 gaattgtctg ttattcatga tatgggcttt gatgattatt tcttggttgt ttgggatttg
    13561 ttgcgttttg gacgatcgaa tggctattat atgggaatgg gaaggggttc tgcagtaggc
    13621 agtttggttt cttatgcctt agacatcacg gggattgacc cagtagagaa aaatctgatt
    13681 tttgaacgct ttcttaatcg tgaacgctat accatgcctg atattgatat tgatatccca
    13741 gatatttatc gtccagattt tatcagatat gttggtaata aatatggtag taaacatgcg
    13801 gcacaaatcg ttactttttc aacctttgga gccaagcaag ctcttcgaga tgtcttgaaa
    13861 cgctttggtg tgccagagta tgaattatct gcaattacta agaaaatcag ttttcgtgac
    13921 aatcttaagt cggcctatga gggcaatctc cagtttcgtc agcaaatcaa tagtaagtta
    13981 gaataccaaa aagcttttga gattgcttgc aagatagagg gctatccaag acaaacctct
    14041 gtccatgcgg ctggtgttgt aattagtgac caagatttaa ccaactatat tcctctaaag
    14101 tatggtgatg aaattccact gactcagtat gatgctcatg gagttgaggc tagcggactt
    14161 ttgaagatgg actttctggg actacgaaat ttgacctttg tccagaagat gcaagagttg
    14221 cttgctgaaa tagaaggtat tcaccttaaa attgaagaaa tagatttgga agacaaagaa
    14281 acgttagatt tatttgcctc tggaaataca aaaggtatct ttcaatttga gcaaccaggt
    14341 gccattcgtc tgcttaagcg tgtgcaacca gtctgttttg aagatgtcgt cgcgactact
    14401 tctctaaatc gaccgggtgc tagtgactat atcaataatt ttgtggcaag aaagcatggg
    14461 caggaagaag tgactgttct ggatccagta ctggaggata ttttggctcc aacctacggc
    14521 ataatgctct atcaggagca ggttatgcag gttgcccagc gatttgccgg atttagtctt
    14581 gggaaagccg atattttgcg tcgggctatg gggaaaaagg atgcctctgc catgcatgag
    14641 atgagggttt cctttattca aggttcatta gaagctggtc atactgtgga aaaagcagag
    14701 caggtctttg atgttatgga gaagtttgca ggttatggtt ttaacaggtc acacgcctat
    14761 gcctactcag ccttggcctt ccagttggct tattttaaaa cacattatcc agccattttt
    14821 tatcaggtca tgttaaattc ttccaacagt gattacttaa tagatgcact tgaagcaggt
    14881 tttgaagtag cctctctatc catcaacacc attccctatc acgataaaat tgccaacaag
    14941 gccatctatc taggtttgaa atccattaaa ggagtcagta atgatttagc tctctggatt
    15001 attgaacata gaccttattc taacattgaa gattttatag ctaaattacc tgagaattat
    15061 ctgaaacttc ctctgctaga acctttggta aaagttggtc ttttcgattc atttgaaaaa
    15121 aatcgtcaaa aagtatttaa taatttagct aatctatttg aatttgtgaa agagttggga
    15181 agtttgtttg gagatgctat ttatagttgg caggaatcgg aagattggac ggaacaagaa
    15241 aaattttata tggaacaaga gcttttaggg ataggtgtca gcaaacatcc actacaagct
    15301 attgcaagta aggctattta cccgattacc ccaatcggaa atttgtcaga aaatagctat
    15361 gctattatct tggttgaagt tcagaaaata aaagtgattc gtaccaaaaa gggtgaaaat
    15421 atggccttct tacaggcaga tgatagtaag aaaaaattgg atgtcactct cttttcagac
    15481 ttatatcgtc aggttggaca ggaaataaaa gagggagcct tctactatgt aaaaggaaaa
    15541 atacaatcac gtgatggccg tctgcaaatg attgcacaag aaataagaga agcagttgct
    15601 gaacgctttt ggatacaggt gaaaaatcat gaatcggatc aagaaatttc acgcatttta
    15661 gaacaattta aaggcccaat cccagtcatc atccggtatg aagaggaaca gaaaaccatc
    15721 gtttctcccc atcattttgt agctaaatcc aatgaattag aggagaaatt gaatgaaatc
    15781 gttatgaaaa cgatttatcg ctaaaaatac ggaaaataga agaattttaa aatcaaatgt
    15841 gatataatca agaagaatgt taaaagaaaa aggagcataa accaatatga aacgtattgc
    15901 tgttttgact agtggcggag acgcacctgg tatgaacgct gccatccgtg cagttgttcg
    15961 tcaagcaatt tcagaaggaa tggaagtgtt tggtatctat gacggatatg ctggtatggt
    16021 tgccggtgaa attcatcccc tagatgcagc ttcagtaggg gacatcattt ctcgtggtgg
    16081 tacttttctt cactcagctc gttacccaga gttcgctcaa cttgaagggc aacttaaagg
    16141 gattgagcaa ttgaaaaaac acggaattga aggtgtagtt gttatcggtg gtgacggatc
    16201 ttaccacggc gctatgcgtt tgactgaaca tggcttccca gctattggtc ttccaggtac
    16261 aatcgataac gatatcgttg gtactgactt tacaatcggt tttgacacag cggttactac
    16321 tgccatggac gctatcgata agattcgtga tacatcatca agtcaccgtc gtacttttgt
    16381 aatcgaagtt atgggacgta acgctggtga tatcgctctt tgggctggta ttgcaactgg
    16441 tgctgatgaa atcatcatcc ctgaagcagg cttcaagatg gaagatatcg tagcaagcat
    16501 caaagctggt tatgaatgtg gtaaaaaaca caatatcatc gtcttagctg aaggtgtgat
    16561 gtcagcggct gaatttggtc aaaaacttaa agaagctgga gatacaagcg accttcgtgt
    16621 aacagaactt ggacatattc aacgtggtgg ttctccaact gcgcgtgacc gtgttttggc
    16681 gtcacgtatg ggtgcacatg ctgttaaact tcttaaagaa ggtatcggtg gtgttgcggt
    16741 tggtattcgt aacgaaaaaa tggttgaaaa tccaattctt ggtactgcag aagaaggggc
    16801 attgtttagc cttactgcag aaggtaagat tgtggttaac aacccgcaca aagccgatat
    16861 tgagctatct agcttgaata agagcttgtc ataatttaca atttagttaa taagaccaaa
    16921 aaggtcatat atataaagga gtcacaaaaa tcatgaacaa acgtgtaaag atcgttgcaa
    16981 ctttgggtcc tgcggtagaa atccgtggtg gtaaaaaatt cggtgaggac ggatactggg
    17041 gtgaaaaact tgatgttgaa gcttcagcta aaaacattgc taaattgatt gaagctggtg
    17101 ctaacacatt ccgattcaac ttctcacacg gcgaccacca agaacaaggt gagcgtatgg
    17161 caactgttaa acttgcggaa aaaattgcag gtaaaaaagt tggtttcctt cttgatacaa
    17221 aaggacctga aatccgtaca gaattgttcg aaggtgaagc taaagaatat tcatacaaaa
    17281 ctggtgaaaa aattcgtgtt gcaactaaac aaggaatcaa atcaactcgt gaagtgattg
    17341 cgttgaacgt tgctggtgct cttgatatct atgatgatgt tgaagttggt cgtcaagttt
    17401 tggttgacga tggtaaactt ggtcttcgtg tggttgctaa agatgatgca actcgtgaat
    17461 ttgaagttga agttgaaaac gatggtatca tcgctaaaca aaaaggtgtg aacatcccta
    17521 acactaaaat tcctttccca gctcttgctg aacgcgataa cgacgatatc cgtttcggtc
    17581 ttgaacaagg tatcaacttc atcgcaattt cattcgtacg tactgcaaaa gatgtgaacg
    17641 aagttcgtgc aatctgtgaa gaaactggaa acggacatgt tcaattgttc gctaaaatcg
    17701 aaaaccaaca aggtatcgat aacttagacg aaatcatcga agcagctgat ggtattatga
    17761 ttgctcgtgg tgatatgggt atcgaagtac cgttcgaaat ggttccagtt tatcaaaaaa
    17821 tgattatcaa gaaagtcaat gctgcaggta aagttgttat cactgcaaca aacatgcttg
    17881 aaacaatgac tgaaaaacca cgtgcaactc gttcagaagt atcagacgta ttcaacgctg
    17941 ttatcgacgg aactgacgct acaatgctgt caggcgagtc tgcaaacggt aaatacccac
    18001 tcgagtcagt aactacaatg gctacaatcg acaagaacgc tcaagctctt cttaatgaat
    18061 acggacgtct tgattcagat tcatttgagc gtaactctaa gacagaagta atggcttctg
    18121 ctgttaaaga tgctactagc tcaatggata tcaaattggt tgtaactctt actaagacag
    18181 gtcatactgc acgtttgatt tctaaatacc gtccaaatgc tgacatctta gcattgacat
    18241 ttgacgaatt gacagaacgt ggcttgatgt tgaactgggg tgttatccca atgttgacag
    18301 atgctccatc ttcaactgac gatatgttcg aaatcgctga acgtaaagcg gtagaagcag
    18361 gtctcgttga gtcaggcgat gatatcgtta tcgttgctgg tgtgccagta ggagaagctg
    18421 ttcgcacaaa cacaatgcgt atccgcacag tacgttaaga aaaatataaa aacctatcat
    18481 atccagcttt ctagcctgta tgatgggctc tttttttgtc cagggggcaa aaagggggca
    18541 aaactttcat aatggattga tactcttcga aaatctcttc aaaccacgtc agcgtcgcct
    18601 taccgtatat atgttactga cttcgtcagt tctatctaca acctcaaagc agtgctttga
    18661 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatg aaataagata
    18721 tgcataaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa tcgcaatcta
    18781 cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta aaacctccaa
    18841 agtagcttgc tccattcttt tacctacgtg agtctagatg ttatttactg ttttagcgtt
    18901 tttgtgttct actctaacca ttatagcatt cttctcagct agtgtactaa ggagtgtgtg
    18961 cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag tatttgcctt
    19021 ttgcaaagtg atcttaaatg cctttctcta aatttacata tcactattgt ttaacaaaat
    19081 ctaatctatt ttaggtcact tattcttttt ttgaaatgta gaatgaactt tttcaaagtt
    19141 tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt tttaattctc
    19201 cctatatagc ctgacaactt tcccgatggt acgaatatgg ttgctttcgt ctaggtggat
    19261 gtcggggtat ttgggattga gtttttttaa ggtagccttg gcggagtttc ttgacatagt
    19321 tagcgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg gtattcttga
    19381 taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg acataagcga
    19441 ttgggtcgta gtcgtctggg ataatggaaa ctccatatct aaatcgttgt cctgcatcga
    19501 gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc tgtagtcgtc
    19561 cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct ctcggcatag
    19621 gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg gatatcgcta
    19681 ggagaatcct tttgaactgg aggaaagagg gcatcgatca agctactgaa tactttaact
    19741 aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt tctaatggtg
    19801 tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt actagtctat
    19861 attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa catttctaga
    19921 aattaatttg actttcctaa tagagttgtt catatcttat ttcaatctat tatgtttttc
    19981 acctctaaca atcgcaatct cttctttatc catgaatgaa atcgctttct atttttgtaa
    20041 gtaaagcata acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc gtaaaaaatt
    20101 tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa taacaaaaaa
    20161 acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat atctgtaaag
    20221 cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag aaatcaagaa
    20281 aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct tgtcaacaac
    20341 aatatgctac ttctgagggg acgaatcaaa ggcaaagcag ttcagcgaaa gttccatgga
    20401 aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa tctctcttat
    20461 cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat gactataata
    20521 ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac accgaatacg
    20581 atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt gggaccaact
    20641 gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag cttgaaaaga
    20701 atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc tttgattcac
    20761 aagataagga agagtttgat attctatttt cgagagttcc aactgaggca actacagatg
    20821 tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc aatgaaaaag
    20881 ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg tttgtaggcc
    20941 acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa ttgactttcg
    21001 aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag tatttgggca
    21061 ccaagtatgc ggattataca ggcaagggac tggctaagcc ttttatcatg gataatgata
    21121 agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt ttatttctat
    21181 ttttgatgac ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc aaaaatgaaa
    21241 catttattgg ctatatccaa agatacgata ttgatgggaa tggctatcaa tcattaccgt
    21301 gtcctcagaa ttgagaggag ttcttgaaat cgtaaaacta ctttgaacaa gagttacttc
    21361 aacccattgg ctccgacgga ttaagttgct ttcgtgaaca ccaaaatcag ccgcaatttc
    21421 ttcataagtg cggtattctc gcacatattg aagagtggcc ataagaaggt cttctaggct
    21481 taatttaggt tttcgtcccc cttttgtgtg tttaagttga taagcagttt ttaatacagc
    21541 taacatctct tcaaaagtgg tgcgctgaac accaacaaga catttaaatc gtgcatcagt
    21601 tagttgctta cttgcttcat aattcataga actactatac catattttgt ttcgcaggaa
    21661 gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt tgtagtttca
    21721 tctgtattag tatataattt aacttagaga aaataggagg actaatcgaa tggaattaaa
    21781 agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt ctaatattag
    21841 tgacaaagaa actactgaga agattctggc gctagtacca caagacttga ttaagcgaat
    21901 cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt caattgaata
    21961 ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaag aacgcgaaga
    22021 attgcgtcag attatcacga ctatctttga acaaaagatg aataagcata gtattaagta
    22081 gagaatgaaa aaatatttta ttagcggttt gggaagcaat gcctatcata gcaaggattt
    22141 ttttcaagaa ctagattcgc aggtctattt tctaaatcca tatgaaaagc atcttcgaga
    22201 tgaaacagaa ttgaaatcat ggtttaaaaa tgagattgta gaggaagaat ctatctgtct
    22261 gataggccat tctcttggag gagatttagc tcgttatttc gcatcggaat ttgaagaagt
    22321 aaagaaactg attcttttgg atggtggcta tctagattta gataagattt tacctttgga
    22381 tacagagtta gaggaaacta aaaattatat caaatctcaa attgtttcgg acttagctct
    22441 tcttatttct aaagagaagt ccgaagcaaa gcattggtca gaaaatatgg agaaagctgt
    22501 aagacagtcc tatcactgga atgttgagta taatagatat gagttggcta taaattatga
    22561 aaatatagaa gcgatactcc gcctacggag aaaaatacaa gcttttaaga gagaagtggg
    22621 agataccttg tttattagtc ctcgctatcc taatggagct acatggagag aggaagccct
    22681 aaaagaattg ccagactatt ttaatactat ttttttagaa aactttggcc atgagcttta
    22741 tactcaagca cctaaagaaa tcgctagtct aatgaatgag tggctcgctt attttctatg
    22801 agctacttgt attgctggaa atggtataag atgaaaatct acaagtcact aattttcata
    22861 taacaaaaaa acgaacaggc tctttttctg ttattcagaa gagaacttgt tcgtttttat
    22921 cttgattttc ttaaaaagct ctatatacat agggattttc tggtttatcg actttggtaa
    22981 agctgtcgat ttccaaggtt ggaaggtttt gtttgagttc tttatggtag tgattgacca
    23041 gttttccttt ggctgtaatc caggtgttgt tttcatactg ccgggtattg cccttggtca
    23101 gcaatccata gacaccagaa tctgcgatac agtggataat gccgaatcgg aacagaaatt
    23161 gactattggc atgactgggg tcgttataga caaagcctgt aaactggatt gtcttgccct
    23221 caaattcatc tggatagtcg tagatagcct ccatgacttc catatagttt tcattagtga
    23281 tctgaatact atcttgggat aagtatttat ccgccgccgt tcgcatttcc ttttcatagg
    23341 ctgattttga aaaataagaa ctagtatctg gtttcaaata ttggcttgtc gtcccttcac
    23401 ttgtctgaat agctagatcc gttccttccg atagggggaa atgataacct ttagcagaaa
    23461 cggtctgaga atccaagcta acagttggga aagttaagcc gatgacaagt ggaatagcca
    23521 gaagagaaat actcgtcatc ttggccaatc ggctgttcag atgactgtgg gttttgactt
    23581 gcttcatcca gatatacaat tgaacaattg ccaagataaa ggaaagcacc atggagatat
    23641 aggccagata ggaatagtgc atgttgatgt actggtttag tttgcccgac agatggaggt
    23701 aaatagtcag ttcaaaatag ccagctaaaa ctaaaaatcg aatcatagga tgactccaat
    23761 caagagagaa taggctaaaa cgaccagagt cacaatcgta atgaagtgac taataaatcg
    23821 tgctttcaag taatttttca tcatgagaat atttttgata tccagcattg ggccaatgac
    23881 gagaaaggcc agaactggtg ccaaaccgaa actcgagagt agagaagcac ctataaaggc
    23941 atccgcctca ctacagagcg aaagaagaaa ggctaaaagc atcaagagca ggatagcaaa
    24001 aagaggagtc gcactgatag aggtcagaat ccgagtcgga acgtagacct gtattataga
    24061 agcaaagagg cagccaaata ccaaataacg ccccgtatca aaaaattcat caatggcctg
    24121 cacaaagact tgaaaaactt tttttgcaga actcaagtaa gaaaaatcat gctcatgaca
    24181 agccagacga ttttctttct gaatcggttc ttgccagaaa aatcctagaa aaattcctag
    24241 tattacagcc acaagaatgg aacccagagc tcgtaatagt gcgacatgga aggagttgcc
    24301 aaaggcagaa taggtcgcaa aaagaacaat gggattgata acaggtgctg tcacaagaaa
    24361 aggaacggcc gtgtaacttg gaaccttttt ttccagaaaa cgattgatga tggggacgat
    24421 tccacattca caagaaggga aaagtatacc gacaaaggtc ccaaaaaaga ttctccccca
    24481 acgatttcga gggagaaaat gataaacctt gtcaggtgtg atataaactt caatcagccc
    24541 tgagacaatg cttcctatca gaacgaaggg aagggcttca atgataatgg agagaaaaat
    24601 ggctccagtt tgaagtacac tagatgggag ttgttgaaaa gcagtcatct agtttttctt
    24661 ttctgctttg acttttttct ctttgtcatc agggaaagta acttgtttca aatcagggag
    24721 tttagcaaac tcttcaaaca tcttgtccaa gtcgtctcgt tttgtaaatt tgacagccat
    24781 aggtgtacct cgattctaaa ttctacctct attatactat tattttgcgg aaaagggagt
    24841 tttttaattt attttcgata gttgatacac ttcgaaaatc tcttcaaacc acgtcagctt
    24901 cgccttaccg tagtacggtt actgacttcg tcagttctat ccacaacctc aaaacagtgt
    24961 tttgagctga cttcgtcagt cttatccaca acctcaaaac agtattttga gcagcctgcg
    25021 gctagcttcc tagtttgctt tttgattttc attgagtatg aaaaggattg gagaaagcct
    25081 tccagcttgt ggtataatag atttatggat aaaaaatatg aaaaaatctc tcaggatttg
    25141 ggagtgacgt taaagcaaat tgataccgtt ctaagtttga cagctgaagg ggcgactatt
    25201 ccctttatcg cgcgttatcg caaggacatg actggtagtc tggatgaggt ggcgattaag
    25261 gctattattg atttggataa aagtctgaca aatctcaatg accgtaagga agctgtctta
    25321 gctaagattc aagaacaagg taagttgacc aaggaattgg aagaagctat cttagttgcc
    25381 gaaaaattag cagacgttga agaactctat cttccttata aggaaaagcg tcgtaccaag
    25441 gcaaccattg cccgtgaagc tggactcttt cctcttgctc gcttgatttt gcagaatata
    25501 gttgacttag agaaagaagc tgaaaagttc gtctgtgaag gatttgcgac tggcaaggaa
    25561 gccttgaccg gtgcagttga tattttggtc gaagccttat cggaagatgt gaccttgcgt
    25621 tctatgactt atcaggaagt gctgagacac tctaaactca cttctcaagc caaggatgaa
    25681 agtcttgatg aaaagcaggt ttttcagatt tattatgatt tttcagagac agttggaact
    25741 atgcaaggct atcgtacctt ggctctcaat cgtggggaga aacttggtgt cttgaagatc
    25801 ggttttgaac atgcgacgga ccgtattctt gccttctttg ctactcgttt caaggtgaaa
    25861 aatgcttata ttgatgaagt tgttcagcaa tccgttaaga aaaaggtctt gcctgctatt
    25921 gagcgtcgta ttcggacaga attaactgag aaagctgaag agggagctat ccaacttttt
    25981 tctgacaatc tgcgcaatct cctcttggtt gctccactga aagggcgcgt ggttcttggg
    26041 tttgacccag cctttcgtac aggtgccaag ctagctgtcg tggatgcaac aggaaaaatg
    26101 ctgacaactc aggttattta tcctgttaaa ccagcatcag ctcgtcaaat cgaagaagcc
    26161 aagaaagatt tagcagattt aattggtcaa tacggtgtag agattattgc cattggaaat
    26221 ggaacggcca gtcgtgaaag tgaagctttt gtagcggaag ttctgaaaga tttccctgaa
    26281 gtcagctatg ttatcgttaa tgaaagtggt gcttctgtct attctgccag cgaacttgct
    26341 cgtcaggagt ttccagactt gaccgttgaa aaacgctctg ccatttctat cgcccgtcgt
    26401 ttgcaagatc ctcttgcgga attggtcaaa atcgatccta agtcaattgg tgtcggtcaa
    26461 taccaacacg atgtcagtca gaagaaacta tctgagagtc tggactttgt tgtcgataca
    26521 gtggttaacc aagttggtgt caatgtcaat acagctagcc cagctcttct ttcacacgta
    26581 gctggactca ataaaaccat ttctgaaaat atcgtcaaat accgtgagga agagggaaaa
    26641 atcacttcac gctcccaaat caagaaagtt cctcgtttgg gggccaaggc ttttgaacag
    26701 gctgctggtt tcctccgtat ccctgaaagt agcaatatcc ttgataatac aggagttcac
    26761 ccagaaaatt acgctgccgt taaggaactc ttcaaatgct tggacattaa ggatctgaat
    26821 gaagaggccc aaagcaaact caagtcgctt tcagtcaagg aaatggcgca agagttagac
    26881 cttggtccag aaactcttaa agatatcatt gcagatcttc tcaaaccagg tcgagatttc
    26941 cgtgattcct ttgatgctcc agttctccgt caagatgtcc tagatatcaa ggacttagtg
    27001 gttggacaaa agctagaagg agtggtgcgt aacgttgttg atttcggtgc ttttgttgat
    27061 atcggaattc atgaggacgg tctcatccat atttcccata tgagtcgcaa gtttatcaaa
    27121 caccctagtc aagtagtggc agttggagat ttggtgagcg tttgggttaa gaaaattgat
    27181 actgaacgtg aaaaagttaa tctgtctctc ctagctccaa atgaaactga ctgattacgt
    27241 caagcaggtt tcactagaag acttcggcag accttttatt catcatgtcc agtggaatag
    27301 gcgtctacgt tcgacaggtg ggcgattttt ccccaaagat gggcatttgg attttaatcc
    27361 caaggtttat caggaactgg ggttggacgt ttttaggaaa attgtccgac atgaactctg
    27421 tcattatcac ctctattttc aagggaaagg ctatcaacac aaggatcggg attttaagga
    27481 actgttgaaa gcagtggatg gattacggtt tgtaccatcc ttgcccaata gtaactccaa
    27541 gccaatcaag ctctatcgtt gccaatcctg ccagcaaact tatcagcgta agcgtaggat
    27601 tgataccaaa cgctatcgct gtggactttg tcgaggaaag ttgctattag taaatcagcc
    27661 tgaggactga tgaaagccga gcctatccgt gatatactat gtctaaccta gcagaaagag
    27721 gaaatatcat gaacagtaag ttttataaaa tgagacgaaa tcgcatgatt tcaggagttt
    27781 tagcaggtct gtcagacaag tggaactttg atgttaccct tgtacgtttt ctgtttgcca
    27841 tttttacagt cgcaaacttt ggacttgggg tgattatcta tatcatccta gcttctatca
    27901 tgccaaccaa ggaagaaatc gaagcagaaa tgtacggaac aggcccacgt aaacgcaaag
    27961 aagctcaagc cattgacgat aatgaaggct ggttttggtg aggttttaca aaagatttgg
    28021 aatacgcaaa aagctttaaa tcaatagtct aaactgcttg atttaaagct tttttacttt
    28081 tatactcaat aaaaatcaaa gtgcaaacta ggaagccagc cgcaggctgt aatttagtcg
    28141 gcaatgtgaa gttgatatag tttgcacttt gatttttgaa tagtattaat aatatttcgc
    28201 cagcttcatc cacaaactat agtggattgg aactagaata ggacacctat acttctaaaa
    28261 aattgttaga aatcgatttg tcctgttctt atttcatttt actataaaag cagtaattta
    28321 aactcagttt tttaatctat ttttgctgct gagacaatac atttttggaa aaatggtgga
    28381 tgctgataac aactgataac cagcaaataa cataagcagt gccggtaaat tctgtaccga
    28441 taaagtgtgt gtgttcaact aagagctgac cgatgaatgg agagagcaga tagagaagtc
    28501 cgatgagtat atgttctttg tgtttcatta aagcgcacct tctttcctta taggttgaac
    28561 gacttgcaag tgttaaattg aatggtatgt tatctaggta accttactaa aatgttagtt
    28621 cccgcttcct ccttttcaaa gtaagccttt ttacacttat attttacaac tttaaaaata
    28681 ggaaatcaaa tcattttcta agtaattttg cttatatttc acccaatctt acaaaaatgt
    28741 aagattaaag tctcttttgt aaggttaggt tatggcaagc ggtctttttt tgatgtaaac
    28801 tagactcata aagaacaaag gagtaacatc atgaaacaaa tcttacataa gaaaactaga
    28861 aaaccaagtc acaaagaaat tgagcgcgtt cagctgggat gcactatgat gcaagctaca
    28921 tttcatttga tgggatatta agaaaggaga ttctcatgac acttttagat gtaaaacacg
    28981 ttcaaaaaat ttataaaaca cgttttcagg gcaaccaagt agaagccctc aaggatattc
    29041 actttaccgt cgaaaagggt gactacgttg ccatcatggg tgagtctggt tctggtaaat
    29101 caactcttct caatattcta gctatgctgg ataaaccaag tcgtggtcag gtttacttga
    29161 atggaactga caccgcaacc attaaaaatt cacaggcctc tagcttccgt cgtgaaaagt
    29221 tgggctttgt cttccaagac tttaacttgc tagatactct atctgtaaag gacaatatct
    29281 tgcttccgct tgtcttgtca agaagaccta ttacagagat gatgaagaaa ttggtggtga
    29341 cagctgagaa tctgggaata aaccaattac aagagaagta cccttacgag atttctggtg
    29401 gccagaaaca gcgtgtagca gtagcacgcg ccatcatcac tgaacctgaa attctccttg
    29461 cggacgaacc gacaggagct cttgactcca agtcatctgc agccttactt gatgtctttg
    29521 atgaaatcaa tgagcgcggc caaaccattc tcatggtaac ccactcaaca gcagcagcta
    29581 gcagagctaa acgtgtactc tttatcaaag acggcattct ttacaatcaa atctaccgtg
    29641 gagagaagac agaacgtcag atgttccaag aaatctctga taccttgact gtcatggcaa
    29701 gcgaggtgaa ttagtatgtt tcgattaacc aataagttag cggtatcgaa cttgattaaa
    29761 aaccgcaaac tctactatcc ttttgcgctg gctgttctct tggcagtcac tgtcacctat
    29821 ctcttttact ctctaacctt caatcctaag attgcggaaa tccgtggagg aacaaccatt
    29881 caggctacac ttggatttgg tatgtttgtc gtcacccttg cgtcagccat tatcgttctc
    29941 tatgccaata gttttgtcat gaagaaccgt tccaaggaac taggaattta tggcatgttg
    30001 ggcttggaga agcgtcatct tatcagtatg acctttaagg agttagtggt atttgggatt
    30061 ctaactgttg gagcgggtat cggtattgga gccttgtttg acaagttaat tttcgctttc
    30121 ctgctcaaac taatgaaatt gaaggttgag ctggttgcta ccttccagac gaaagttgtc
    30181 attacagtgc ttgttgtctt cggtttgatt ttcctaggcc tcatgttcct gaatgccctt
    30241 cgaatcgccc gtatgaatgc cctccagctc tctcgtgaga aagctagtgg agagaaaaaa
    30301 ggtcgcttcc ttcctctcca aaccattctt ggttccataa gtttaggaat tggctattat
    30361 cttgccctta cggtaaaaga tcctcttaca gccttaacaa ccttcttcat agctgtttta
    30421 ctggttatct ttgggactta tctcttgttt aatgcaggga ttaccgtttt cctccaaatc
    30481 ttaaagaaaa ataagaaata ctattaccaa cctaataatc tcatatctgt ttctaacttg
    30541 attttccgta tgaagaaaaa tgcagttgga ctagcaacta tcgctatttt gtcaacaatg
    30601 gttttggtaa ccatgtcagc agcgacaagc attttcaatt ccgcagaatc ctttaaaaaa
    30661 gttctaaatc ctcatgattt tggggtttca gggcaaaatg ttgaaaaaga agatttggac
    30721 aaactcttga gccagtttgc aagtgacaaa ggttataaga ttaaagagaa agaagtgctt
    30781 cgttacactt actttgctgt tgcgaatcaa gaaggaacca agttaactat ttttgaaaaa
    30841 ggacaaaacc gtgtccaacc aaaaacagtt ttcatggtat ttgaccaaaa agattatgaa
    30901 aatatgactg gtcaaaaact gtctctatca ggaaatgagg tcggtctctt tgtcaaaaat
    30961 gacggactga aaggacagaa aactctaact ctaaatgatc atcaattttc tgtcaaagaa
    31021 gaatttaata aagatttcat tgtcaaccat gttccaaata agtttaatat cttgactact
    31081 gattacaatt accttgttgt tcctgattta caagcctttt tggatcaatt cccagattcg
    31141 gctatctata atcagtttta cggtggtatg aatgtagatg ccagcgaaga agaacaactc
    31201 aaggtcgctg aggagtatga aaactacctc aatcaattta atgctcaatt agacacagaa
    31261 ggtagctatg tttatggtag caatctagca gatgctagtt ctcagatgag tgccctcttt
    31321 ggtggtgtct tctttatcgg tattttccta tccattatct ttatggtcgg aactgttctg
    31381 gtcatctact acaaacaaat ttctgaaggc tacgaagacc gtgagcgctt tattatcttg
    31441 cagaaagtcg gtttggacca aaagcaaatc aagcaaacca tcaacaaaca ggttttaact
    31501 gttttcttcc ttcctttgct ctttgccttc atacatctcg cctttgccta ccatatgctt
    31561 agcctgattt taaaagtgat tggtgtactg gatacgacta tgatgttgat tgtgaccttg
    31621 tctatctgcg ctatcttcct catcgcctat gtgctgattt tcatgattac ttcaagaagt
    31681 tatcgcaaga ttgtgcaaat gtaaaaaaga tacctcgact tcaaaatcga ggtatttctt
    31741 gtattctaaa tgttgaaaag ttgttcgagc aggaaggtaa ctcccatggt caagagacca
    31801 atagcaaggt tccgaatcat agctgttcta gtcggatcct ttccaagtct ggcactagtg
    31861 taaccagtga gaagaagggc cacaccgaca ataaggacag tagcagggat gcgatattca
    31921 cttgggaata tggtcactga cagcattgga ggcaaacttc taaggaaaaa ggcaacgaag
    31981 ctagaaatgg cagcgtgcca aggattggta aattcttcat actcaatccc atatttttcc
    32041 tctaccagag ccttgagtgg atttttaaga aagatcttat tggtcaagag ttgggcagaa
    32101 gttttgcatt ctccattttg gatataagca gcatagaggg attttttggc tagttcccta
    32161 tcttggtcta acaagagttt ttctcgcgaa acggcagctt cctcggtatc ttttggagtt
    32221 gaaacggata catattctcc accagccatt gaaaaggcac cagctaagat agccgcaaat
    32281 cctgataaaa agataatcca gatattggtc gtggcactgg caaccccgat aaccacacca
    32341 gcaatggaaa taattccatc gttagcacca agaacacctg cgcgcaggat atttaaacga
    32401 cctgcaaaat ttgaatcgat ttcgtgattt gtttctgacg ctaaatttca agttcaagtt
    32461 agccatcaag aagtcttctc tgggtgactt gtagttcaag cattttttag gatagttgtt
    32521 aatccacttt tcgatgaatg cgacttcttt gggagtcatt ttcttggttc ccttaggtaa
    32581 ccatctatga atgagcctgt tgtgattctc attagttccc ctttcccaag aggcataggg
    32641 gtgcgcataa tagatgtgct cctcagaaaa tacatcaaac aagcgattga attccgttcc
    32701 attatctgcc gtgatggaaa gaatcttgtg ttgttttaag atgagtttta gagcctgatt
    32761 gaccacctca gcacttttat ttggaatcaa tcggatgatc tgatgtctac tctttcgatc
    32821 tgtcaagaca agcaagcagt agtttttcgc tctcgtaagt agaaccgtat caatctcata
    32881 atgcccattc tccaagcgaa gattgatagc ttcagaccgc tgttcgatgg attgaccagc
    32941 aggtttaaag ttggtgctag cctgtttctt atcaggcgaa aatttttggt tatgatagtg
    33001 gagaatcttt tcctttagtt ccttggtcaa gcttgatttc ttgaccgagc gcttgcgatt
    33061 gttttcataa gactgttgag catagtcggc agaataaact tctttgaagc gcccttttcc
    33121 aagacattgt cggactgtcc c
//
LOCUS       DAVHBD010000024        32865 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000024 DAVHBD010000000
VERSION     DAVHBD010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32865
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.024"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            311..2464
                     /locus_tag="VVK04_001172"
     CDS             311..2464
                     /locus_tag="VVK04_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU3989830.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2477..3826
                     /locus_tag="VVK04_001173"
     CDS             2477..3826
                     /locus_tag="VVK04_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU3989831.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            3996..4703
                     /locus_tag="VVK04_001174"
     CDS             3996..4703
                     /locus_tag="VVK04_001174"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU3989832.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            4760..8485
                     /locus_tag="VVK04_001175"
     CDS             4760..8485
                     /locus_tag="VVK04_001175"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU3989833.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            8578..10020
                     /locus_tag="VVK04_001176"
     CDS             8578..10020
                     /locus_tag="VVK04_001176"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU3989834.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGTGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAVCSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSMTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10057..11079
                     /locus_tag="VVK04_001177"
     CDS             10057..11079
                     /locus_tag="VVK04_001177"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU3989835.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11076..11621
                     /gene="purN"
                     /locus_tag="VVK04_001178"
     CDS             11076..11621
                     /gene="purN"
                     /locus_tag="VVK04_001178"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU3989836.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            11705..12214
                     /locus_tag="VVK04_001179"
     CDS             11705..12214
                     /locus_tag="VVK04_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU3989837.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12239..13786
                     /gene="purH"
                     /locus_tag="VVK04_001180"
     CDS             12239..13786
                     /gene="purH"
                     /locus_tag="VVK04_001180"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU3989838.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            13908..15170
                     /gene="purD"
                     /locus_tag="VVK04_001181"
     CDS             13908..15170
                     /gene="purD"
                     /locus_tag="VVK04_001181"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU3989839.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTAIYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQLILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            15573..16061
                     /gene="purE"
                     /locus_tag="VVK04_001182"
     CDS             15573..16061
                     /gene="purE"
                     /locus_tag="VVK04_001182"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU3989840.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16048..17139
                     /gene="purK"
                     /locus_tag="VVK04_001183"
     CDS             16048..17139
                     /gene="purK"
                     /locus_tag="VVK04_001183"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU3989841.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17149..17376
                     /locus_tag="VVK04_001184"
     CDS             17149..17376
                     /locus_tag="VVK04_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU3989842.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17439..18737
                     /gene="purB"
                     /locus_tag="VVK04_001185"
     CDS             17439..18737
                     /gene="purB"
                     /locus_tag="VVK04_001185"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU3989843.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(18792..22727)
                     /gene="strH"
                     /locus_tag="VVK04_001186"
     CDS             complement(18792..22727)
                     /gene="strH"
                     /locus_tag="VVK04_001186"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU3989844.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNNYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRYT
                     AESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIARLQETVNNLTLTPEAQKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTTLTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGF
                     LKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(23042..23758)
                     /locus_tag="VVK04_001187"
     CDS             complement(23042..23758)
                     /locus_tag="VVK04_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU3989845.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24106..25893
                     /locus_tag="VVK04_001188"
     CDS             24106..25893
                     /locus_tag="VVK04_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU3989846.1"
                     /translation="MTRFEIRDDFYLEGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            25890..26366
                     /locus_tag="VVK04_001189"
     CDS             25890..26366
                     /locus_tag="VVK04_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU3989847.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26394..27299
                     /locus_tag="VVK04_001190"
     CDS             26394..27299
                     /locus_tag="VVK04_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU3989848.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27286..28101
                     /locus_tag="VVK04_001191"
     CDS             27286..28101
                     /locus_tag="VVK04_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU3989849.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28108..28512
                     /locus_tag="VVK04_001192"
     CDS             28108..28512
                     /locus_tag="VVK04_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU3989850.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            28806..29972
                     /locus_tag="VVK04_001193"
     CDS             28806..29972
                     /locus_tag="VVK04_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU3989851.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30088..31125
                     /locus_tag="VVK04_001194"
     CDS             30088..31125
                     /locus_tag="VVK04_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU3989852.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31332..32186
                     /locus_tag="VVK04_001195"
     CDS             31332..32186
                     /locus_tag="VVK04_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU3989853.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            32336..32593
                     /locus_tag="VVK04_001196"
     CDS             32336..32593
                     /locus_tag="VVK04_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU3989854.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
BASE COUNT         9038 a         6446 c         7724 g         9657 t
ORIGIN      
        1 ccatattttc taggtagaac gtttgttctg cctatttttt tatccaaaaa gtgcagttgg
       61 gagggagata ggctcatttg ggaaggaagt ccagtttttg tttagtgatt ggggtaagat
      121 agttgttatc agatgagttt atactcttcg aaaatcaaat tcaaaccacg tcaacgtcgc
      181 cttgccgtat atatgtgact gacttcgtca gtcctatcta caacctcaaa acagtgtttt
      241 gagcagcctg cggctagttt cctagtttgc tctttgattt tcattgagta ttagggaaaa
      301 ggagatgaat atgaaatttg ggaaacgtca ctatcgtccg caagtggatc agatggactg
      361 cggtgtagct tcattagcca tggtttttgg ctactatggt agttattatt ttttggctca
      421 cttgcgagaa ttggctaaga cgaccatgga tgggacgacg gctttgggct tggtcaaggt
      481 ggcagaggag attggttttg agacgcgagc cattaaggcg gatatgacgc tttttgactt
      541 gccggatttg acttttcctt ttgttgccca tgtgcttaag gaagggaaat tgctccacta
      601 ctatgtggtg actgggcagg ataaggatag cattcatatt gccgatccag atcccggggt
      661 gaagttgact aaactgccac gtgagcgttt tgaggaagaa tggacaggag tgactctttt
      721 tatggcacct agtccagact ataagcctca taaggaacaa aaaaatggtc tgctctcttt
      781 tatccctata ttagtgaagc agcgtggctt gattgccaat atcgttttgg caacactctt
      841 ggtaaccgtg attaacattg tgggttctta ttatctgcag tctatcattg atacctatgt
      901 gccagatcag atgcgttcga cactagggat tatttctatt gggctagtca tcgtctacat
      961 cctccagcaa atcttgtctt acgctcagga gtatctcttg cttgttttgg ggcaacgctt
     1021 gtcgattgac gtgattttgt cctatatcaa gcatgttttt cacctcccta tgtccttctt
     1081 tgcgacacgc aggacagggg agatcgtgtc tcgttttaca gatgctaaca gtatcatcga
     1141 tgcgctggct tcgaccatcc tttcgatttt cctagatgtg tcaacggttg tcattatttc
     1201 ccttgttcta ttttcacaaa ataccaatct ctttttcatg actttattgg cgcttcctat
     1261 ctacacagtg attatctttg cctttatgaa gccgtttgaa aagatgaatc gggataccat
     1321 ggaagccaat gcggttctgt cttcttctat cattgaggac atcaacggta ttgagactat
     1381 caagtccttg accagtgaaa gtcagcgtta ccaaaaaatt gacaaggaat ttgtggatta
     1441 tctgaagaaa tcctttacct atagtcgagc agagagtcag caaaaggctc tgaaaaaggt
     1501 tgcccatctc ttgcttaatg tcggcattct ctggatgggg gctgttctgg tcatggatgg
     1561 caagatgagt ttggggcagt tgattaccta taataccttg ctggtttact ttaccaatcc
     1621 tttggaaaat atcatcaatc tgcaaaccaa gcttcagaca gcgcaggttg ccaataaccg
     1681 tctaaatgaa gtgtatctag tagcttctga gtttgaggag aagaaaacag ttgaggattt
     1741 gagcttgatg aagggagata tgaccttcaa gcaggttcat tacaagtatg gctatggtcg
     1801 agacgtcttg tcggatatca atttaaccgt tccccaaggg tctaaggtgg cttttgtggg
     1861 gatttcaggg tcaggtaaga cgactttggc caagatgatg gttaattttt acgacccaag
     1921 tcaaggggag attagtctgg gtggtgtcaa tctcaatcag attgataaaa aagccctgcg
     1981 ccagtacatc aactatctgc ctcaacagcc ctatgtcttt aacggaacga ttttggagaa
     2041 tcttcttttg ggagccaagg aggggacgac acaggaagat atcttacggg cggtcgaatt
     2101 ggcagagatt cgagaggata tcgagcgcat gccactgaat tatcagacag aattgacttc
     2161 ggatggggca gggatttcag gtggtcaacg tcagagaatc gctttggcgc gtgctctctt
     2221 gacagatgcg ccggtcttga ttttggatga ggcgactagc agtttggata ttttgacaga
     2281 gaagcggatt gtcgataatc tcattgcttt ggacaagacc ttgattttca ttgctcaccg
     2341 cttgactatt gctgagcgga cagagaaggt ggttgtcttg gatcagggca agattgtcga
     2401 agaaggaaag catgctgatt tgcttgcaca gggaggcttt tacgcccatt tggtcaatag
     2461 ctagaaagag gagaggatga aaccagaatt tttagaaagt gcggagtttt ataatcgtcg
     2521 ttaccataat ttttccagta gtgtgattgt acccatggcc cttctgctcg tgtttttact
     2581 tggctttgca actgttgcag agaaggagat gagtttgtcc actagagcta ctgtcgaacc
     2641 cagtcgtatc cttgcaaata tccagtcaac tagcaacaat cgtattcttg tcaatcattt
     2701 ggaagaaaat aagctggtta agaaggggga tcttttggtt caataccaag aaggggcaga
     2761 gggtgtccaa gcggagtcct atgccagtca gttggacatg ctaaaggatc aaaaaaagca
     2821 attggagtat ctgcaaaaga gcctgcaaga aggggagaac cactttccag aggaggataa
     2881 gtttggctac caagccacct ttcgcgacta catcagtcaa gcaggcagtc ttagggctag
     2941 tacatcgcaa caaaatgaga ccatcgcgtc ccagaatgca gcagctagcc aaacccaagc
     3001 cgaaatcggc aacctcatca gtcaaacaga ggctaaaatt cgcgattacc agacagctaa
     3061 gtcagctatt gaaacaggta cttccttggc cggtcagaat ctagcctact ctctttacca
     3121 gtcctacaag tctcagggcg aggaaaatcc ccaaactaag gttcaggcag ttgcacaggt
     3181 tgaagcacag atttctcagt tagaatctag tcttgctact taccgtgtcc agtatgcagg
     3241 ttcaggtacc cagcaagcct atgcgtcagg gttaagcagt caattggaat cccttaaatc
     3301 ccaacacttg gcaaaggttg gtcaggaatt gacccttcta gcccagaaaa tcttggaggc
     3361 agagtcaggt aagaaggtac agggaaatct tttagacaag gggaaaatta cggcaagtga
     3421 ggatggggtg cttcatctta atcctgagac cagtgattct agcatggttg cagaaggtgc
     3481 cctactagcc caactttatc catctttgga aagagaaggg aaagccaaac tcacagccta
     3541 tctaagttca aaagatgtag caagaatcaa ggtcggtgat tctgttcgct atactacgac
     3601 tcatgatgcc gggaatcaac ttttcctaga ttctactatt acaagtattg atgcgacagc
     3661 tactaagact gagaaaggga atttctttaa aatcgaggcg gagactaatc taacttcgga
     3721 gcaggctgaa aaacttaggt acggggtgga aggccgcttg cagatgatta cgggcaagaa
     3781 aagttatcta cgttattatt tggatcaatt tttgaacaaa gagtaatgtt cgtgttttta
     3841 gagttaaata atttttaaac tgtgagaaag attcttcttg cagttttttc tttacaattt
     3901 ttgaaaaaca tctactattt attcggttaa attcttgtgt tttttggttt tttgtggtaa
     3961 aatgtgctca agtaatacga aaggcgaact ttaaaatgtc aaaacaattg atctattcgg
     4021 gaaaagctaa agatatctat acaactgagg atgaaaatct tattatttca acttacaagg
     4081 accaggcgac tgctttcaac ggtgtcaaga aggagcagat tgcaggtaag ggagtcttga
     4141 ataatcagat ctcatctttt atttttgaga aattaaatgc ggctggtgtg gcgactcact
     4201 ttgtggagaa actttcagac acggaacaac tcaataaaaa ggttaagatt attcctttgg
     4261 aagtcgtgct ccgcaactat actgctggtt ccttttcaaa acgttttggt gtggatgagg
     4321 gaatcgcctt ggagactccg attgtcgaat tttactacaa aaatgatgat ttggatgatc
     4381 catttatcaa tgatgagcat gtgaaattcc tacagattgc gggtgaccag cagattgcct
     4441 acttgaagga agaaacgcgt cgtatcaatg aactattgaa agtctggttt gctgagattg
     4501 ggcttaaatt gattgacttt aagctagagt tcggttttga caaggatggc aagattatct
     4561 tggcagacga attttcacca gataactgcc gcttgtggga cgctgatggc aaccacatgg
     4621 ataaggatgt tttccgtaga ggattgggag aactaaccga cgtttatgag attgtttggg
     4681 aaaagttgca gggtttaaaa taacaacctc aaggctgttt gggaatattg caagagctga
     4741 aataaaggaa taagaattga tggataaacg tatttttgtt gaaaaaaagg ctgattttca
     4801 ggtcaagtca gagagtttgg ttagagagct ccagcacaac ttgggactgt caagcttgaa
     4861 aagtattcgt attgtgcaag tatatgatgt atttgacttg gttgaggact tgtttgcacc
     4921 tgcagagaag cacattttct ctgagcaggt aaccgaccat gttttagatg aagtatctgt
     4981 gcaggcggat cttgctaact atgctttctt tgccattgaa agtctaccag ggcagtttga
     5041 ccagcgtgca gcttcgtcac aggaagcctt gcttttgttg ggaagttcga gtgacgtgac
     5101 agtcaacaca gcccaacttt acttggtgaa taaagatatt gatgcgactg agttggaagc
     5161 tgtcaaaaac tacctgctca atccagttga ttctcgtttc aaggatatca cgatagggat
     5221 tgccaagcag gagttttcag agtcagacaa gaccattcca aaattgcctt tctttgaaag
     5281 ctatacagca gaagactttg ctcgctacaa ggccgaacaa gggatggcca tggaagtgga
     5341 tgatttgctc tttatccaag actactttaa gtcaatcggg cgcgtgccaa ctgagactga
     5401 actcaaggtt ttggacactt actggtctga ccactgccgt catacgactt ttgagacaga
     5461 gttgaaacac atcgactttt cagcttctaa atttcaaaag caattgcagt caacctatga
     5521 caagtatatt gccatgcgcg aggaattagg tcggtctgaa aaaccacaaa ccttgatgga
     5581 tatggcgact attttcggtc gttatgagcg tgctaatgga cgattggatg atatggaagt
     5641 ctctgacgaa atcaatgcct gctcagttga aattgaagtg gacgttgatg gtgtcaagga
     5701 accttggctc ctcatgttta aaaacgaaac tcacaaccat ccaacagaaa ttgagccatt
     5761 tggtggagcg gctacctgta tcggtggagc tattcgtgat ccgttgtcag gccgttccta
     5821 tgtttaccaa gccatgcgta tttcaggtgc tggtgatatt acagcaccga tttcggaaac
     5881 tcgtgctggg aaattgccac aacaagtcat ttctaaaaca gcaactcatg gttattcttc
     5941 atatggtaac cagattgggc ttgccacaac ctacgttcgt gaatacttcc acccaggctt
     6001 tgtagctaaa cgtatggaac ttggtgccgt tgttggtgcg gctcccaagg gcaatgttgt
     6061 ccgtgaaaaa cctgaagcag gtgatgtgat catccttctc ggaggtaaaa caggtcgtga
     6121 tggtgtcggt ggtgcgacgg gctcttctaa ggttcaaaca gttgagtctg tagagactgc
     6181 tggtgctgag gttcaaaaag gaaatgccat cgaagaacgc aagattcagc gcctcttccg
     6241 taatggcaat gtcactcgtc tgatcaagaa gtccaatgac tttggggcag gcggtgtctg
     6301 tgtggctatc ggtgaattgg cagacggtct tgaaatcgac ctcaacaagg tgcctcttaa
     6361 ataccagggc ttgaatggta cagaaattgc catctctgaa tcacaagaac ggatggcggt
     6421 cgtggttcgt cctgaagatg tggatacctt cgttgccgaa tgtaacaaag aaaatattga
     6481 tgctgttgtg gtggcgacag taactgaaaa accaaatctt gtcatgcact ggaatggtga
     6541 gacaatcgtt gacttggagc gtcgtttcct tgacatcaat ggtgtgcgcg tggttgtcga
     6601 tgccaaagtt gtggacaagg atgtcaaact cccagaagag cgtcaaacat ctgctgaaac
     6661 actggaatca gataccctta cggttctatc tgacctcaac catgcaagtc aaaaaggatt
     6721 acagactatc tttgactgct ctgttggacg ctcaacggtt aatcacccac ttggtggtcg
     6781 ttaccaactc acaccaactg aggcatctgt gcagaaattg ccagttcaac acggtgtgac
     6841 tcatactgcg tcggtcattg ctcaaggttt caacccatat gtagctgaat ggtctccata
     6901 ccacggtgct gcttatgcgg ttatcgaagc aactgctcgt ttggtggctg ctggtgccaa
     6961 ctggtccaag gctcgtttct cttaccaaga atatttcgag cgtatggaca agcaagcaga
     7021 gcgttttggt cagccagtag ccgctcttct aggctctatt gaagctcaga ttcaacttgg
     7081 cttgccatct atcggtggta aggactccat gtctggtacc tttgaagaat tgaccgttcc
     7141 gccaaccttg gttgcctttg gggtgacgac ggcagatagc cgtaaggtgc tctctccaga
     7201 atttaaagct gttggggaaa atatctacta catcccaggt caagccctct ctgcagagat
     7261 tgattttgac ttgattaaga aaaattttgc tcagtttgaa gcaagccaag ctgaccataa
     7321 agtgacatct gcatcagctg tcaaatacgg tggtgtagtt gaaagtttgg ctcttgctac
     7381 ctttggaaac tatattggtg cagaggtgac cttgcctgaa cttaaaacag ctttgacagc
     7441 tcaattaggc ggctttgtct tcacatctcc tgaagaaatt gctggagtag agaagattgg
     7501 acaaacgaaa gcagacttta cactgactgt caacggtgtg aagctagatg gacacaagct
     7561 tgacagtgca tttcaaggga cattggaaga agtttaccca acagaattta cccaagcgaa
     7621 agaactagaa gaagtaccag ctgtggcatc agatgttgtg attaaagcca aagaaaaggt
     7681 tgaaaaacct gtggtttaca tcccagtctt tccaggaacc aactcagaat atgattcagc
     7741 taaggccttc gaaaaagaag gtgcagaggt caatttggtg ccattcgtga ccttgaatga
     7801 agaagctatt gtcaagtcag ttgaaactat ggttgacaat atcgacaaga ctaatattct
     7861 cttctttgct ggtggattct cggctgcgga tgaaccagat ggttcagcta agtttatcgt
     7921 caatatcctg cttaatgaaa aagtgcgtgt ggctattgat agctttatcg cccgtggtgg
     7981 tttgattatc ggtatttgta atggattcca agccttagtc aaatcgggtc tcctacccta
     8041 cggaaacttt gaagatgcta acaatactag cccaaccctc ttctacaatg atgccaacca
     8101 acacgtggcc aagatggtgg aaactcgcat tgccaatacc aactcaccat ggttggctgg
     8161 tgtgcaagtg ggcgatatcc acgctattcc tgtttcgcac ggtgaaggga agtttgtcgt
     8221 gacggctgag gaatttgcag agctccgtga caatggacaa attttcagcc aatacgttga
     8281 ctttaacggt aaaccaagta tggattctaa gtacaatccg aatggttctg tccatgccat
     8341 cgaaggaatt accagcaaga atggtcaaat catcggtaag atgggccatt cagaacgtta
     8401 tgaggacggt cttttccaaa atatcccagg caataaagac cagcacctgt tcgcgtcagc
     8461 ggttaaacat ttcactggaa aataagactt acagattttc taatagatag tatcagtaat
     8521 gtaaaagtca tgtaaatcta gctcttgatg attacaaatg aaaattaggt ataaaaaatg
     8581 acatacgaag taaaatctct taatgaagaa tgtggtgttt tcggtatttg gggacatcca
     8641 gatgctgcta agttgaccta ttttggactc cacagtcttc aacaccgtgg tcaggagggg
     8701 gcaggaatcc tctccaatga tcaaggacaa ctgaagcggc atcgcgatat gggtcttcta
     8761 tcagaagtct tcagaaatcc tgctaactta gataaattga cgggaactgg tgcgattggg
     8821 catgtgcgtt acgcgactgc tggcgaagct tctgtagata atatccagcc cttcctcttc
     8881 cgttttcacg atatgcagtt tggcttggct cataatggaa atctgaccaa tgcagcctct
     8941 ctcaagaaag aactggaaca aagaggagca attttcagcg cgacttcgga ctctgaaatc
     9001 ttggctcacc tcattcgtcg cagtcataat cctagcctga tgggcaaaat caaggaagcg
     9061 ctcagccttg tcaaaggtgg ttttgcctat atcttgctgt ttgaggacaa gttgattgcg
     9121 gctcttgacc caaatggatt ccgaccgctt tcgattggta aaatggctaa tggagcagtt
     9181 gttgtatctt ctgaaacctg tgcttttgag gtcattggtg ccgagtggat tcgtgatttg
     9241 aagccaggtg agattgtgat cattgatgac gagggcattc agtatgacag ctatacagat
     9301 gatacccagt tggcggtttg ttctatggag tatatctact ttgctcgccc tgattctaat
     9361 atccacggtg tcaatgtcca tacggcacgt aagagaatgg gagcgcaatt ggcgcgagaa
     9421 tttaagcatg aggcagatat tgtagttggt gtgcccaatt cttccctaag cgcggctatg
     9481 ggatttgcgg aagaatcagg cttaccaaat gaaatgggtc tgatcaaaaa ccaatacacc
     9541 cagcgaactt ttatccaacc gactcaagaa ttgcgggagc aaggagtgcg gatgaaactg
     9601 tctgctgttt cgggtgttgt caaaggcaaa cgtgtggtca tggtggatga ttccattgta
     9661 cgtggaacaa cctctcgtcg tatcgttcag ctcttgaaag aagcgggtgc gactgaggtt
     9721 cacgttgcca ttggaagtcc tgcactagcg tatccatgtt tctacgggat tgatatccag
     9781 acccgtcagg agctgattgc agccaatcat acggtcgaag aaactcgcca aatcattggt
     9841 gcggacagta tgacttatct ttcaattgat ggcttgattg agtcgattgg tatcgaaaca
     9901 gatgcgccga acggtggtct ctgtgtcgct tactttgacg gtgactaccc aacgcctctc
     9961 tatgactacg aagaagacta tcgtagaagt ttggaagaaa agaccagttt ttacaagtag
    10021 gcgacagatt ctccattaaa gaaaaggaaa aaacaaatga caaataaaaa tgcatatgcc
    10081 cagtcgggtg tggatgttga agcgggttat gaagttgttg aacggattaa aaagcacgtg
    10141 gcccgtacgg agcgtgcagg tgtcatggga gctcttggtg gctttggtgg tatgtttgac
    10201 ctttccaaga ctggggttaa agaacccgtc ttgatttcag ggactgacgg tgtcggaacc
    10261 aagctcatgt tggctatcaa gtacgacaag cacgatacca tcgggcagga ctgtgtggcc
    10321 atgtgtgtca acgacatcat tgctgcaggt gcggaacccc tctattttct cgactacgta
    10381 gcgacaggga agaatgaacc agctaagcta gaacaagtgg ttgctggtgt ggcagaaggt
    10441 tgtgtgcagg ctggtgctgc cctcatcggt ggggaaacgg ctgaaatgcc gggcatgtac
    10501 ggcgaagacg actatgactt ggctggtttt gcggtcggtg tggctgaaaa atctcaaatc
    10561 attgacggtt caaaggtggt agagggagat gttcttctcg gacttgtttc aagtgggatt
    10621 cactcaaatg gttactcttt ggttcgtcgt gtctttgcgg attacacagg tgaggaagtc
    10681 ctaccagaat tggaaggcaa gaaacttaag gaagttctac ttgagccgac tcgtatctat
    10741 gtcaaggctg tcttgccgct catcaaagaa gagttggtca acggcattgc ccacatcaca
    10801 ggtggtggct ttatcgaaaa tgtccctcgt atgtttgcag atgacctagc tgctgaaatt
    10861 gatgaaagca aagttccagt gcttccaatt ttcaaagccc ttgaaaaata tggtcagatt
    10921 aaacacgaag aaatgtttga aatcttcaat atgggtgtgg gacttatgtt ggcggtcagc
    10981 cctgaaaatg tagagcgtgt aaaagaattg ttggatgaag cagtctatga aattggtcgc
    11041 atcgtcaaga aagaaaacga aagtgtcatt atcaaatgaa aaaaatagcg gtttttgcct
    11101 ctggtaatgg ctcaaatttt caggtgattg ccgaagaatt tccagtggag tttgtctttt
    11161 cagaccatcg tgatgcctat gtgcttgagc gtgcaaagca gctcggcgtt ctgtcctatg
    11221 cttttgaact caaggagttt gagagcaaga cagactacga agcagccctt gtcgaactct
    11281 tggaagaaca ccagattgac ttggtttgcc tagcaggcta catgaaaatc gttggaccaa
    11341 ccttattgtc ggcttatgaa ggtcggattg tcaacattca tccagcctac ttgccagaat
    11401 ttccaggagc tcatgggatt gaggatgctt ggaatgctgg cgtgggtcag tctggtgtga
    11461 ccattcactg ggtggattcg ggtgtggata caggccaggt catcaaacag gttcgtgtgc
    11521 cacgactagc tgatgatacc attgacagat ttgaagctcg catccatgaa gcagagtaca
    11581 ggttgtatcc ggaagtagtg aaggctctat ttacagattg actttttgat gattcatatg
    11641 atatctttga ttttaaattg gagtcagtgt ttgttgaaga cggcttcaaa cggaggtatt
    11701 tgtaatgtta gaatctaaaa aaacaactcg atatgtattt tatgtctatc tgatgttatt
    11761 aacttgggga atcttattta agtttgaaac aaatcctgaa tttatagcat ttttcttagc
    11821 tccaaggtat atcaattgga ttccattttc agaaccacta atagtcgatg gaaaaattgt
    11881 ttttgctgaa atgttattta atctgatttc ctttattcca ttaggtgttt gtttcccttt
    11941 gataaaaact aatttatcta gtttaagaat agtcgggaca ggtttcttga ttagtttatt
    12001 gtttgagtgc ttacagtata ttttagcaat aggtataaca gatataacgg atttgacttt
    12061 aaatacgcta ggtgtctgtg taggcttact gatttatcaa atttttataa gagtgttcaa
    12121 atcacagact agaaaatgga tcaatatctt aggtatgctt agccttggtt ttgcttatct
    12181 tgttttactg ttactgcatt taattggtgt ttaactaatg attaaaaagg agaatataat
    12241 gactaaacgc gtcttaatca gcgtctcaga caaagcgggc attgttgaat ttgcccaaga
    12301 actcaaaaaa cttggttggg agattatctc aacaggtgga actaaggttg cccttgataa
    12361 tgctggggtg gataccattg ctatcgatga tgtgactggt ttcccagaaa tgatggacgg
    12421 tcgtgtgaag accctccacc caaatatcca cggagggctt ctcgctcgtc gtgacttgga
    12481 tagccacttg gaagcggcta aggacaacaa gattgagctc attgaccttg tggtggtcaa
    12541 cctttaccca tttaaggaaa ctatccttaa accagatgtg acttatgctg atgcagttga
    12601 aaatatcgat attggtgggc catctatgct tcgttcagca gcgaaaaatc atgccagtgt
    12661 tacagttgtg gtagatcctg ctgactacgc tgtggttttg gatgaattgg cagcaaacgg
    12721 cgaaacctct tatgaaactc gccaacgttt agcagccaaa gtatttcgtc acacagcggc
    12781 ttatgacgcc ttgattgcag aatacttcac agctcaagtg ggtgaaagca agcctgaaaa
    12841 actcactttg acttatgacc tcaagcaacc aatgcgttac ggtgagaatc ctcaacaaga
    12901 cgcggacttt taccagaaag ctttgcctac agactactcc attgcttcag ccaaacagct
    12961 caacgggaaa gaattgtcat ttaataatat ccgtgatgca gatgctgcta tccgtatcat
    13021 ccgtgacttc aaagatagtc caaccgttgt ggctctcaaa cacatgaatc catgtggaat
    13081 tggtcaagct gatgacatcg agactgcttg ggactacgct tatgagtctg acccagtgtc
    13141 tatctttggt gggattgtcg tcctcaaccg tgaggtggat gctgcgacag ctgagaagat
    13201 gcacggcgtt ttcctcgaaa tcatcattgc accaagctat acggatgaag cgctagccat
    13261 tttgatcaat aaaaagaaaa acttgcgtat ccttgccttg ccatttaatg ctcaagaggc
    13321 tagcgaagtg gaagcagaat acacaggtgt agtcggtgga cttctcgtgc aaaatcaaga
    13381 cgtggtcaag gaaagcccag ctgactggca agtggtgact aaacgtcagc caactgagac
    13441 agaagcgact gctcttgagt tcgcttggaa ggctatcaag tacgtcaaat caaatggtat
    13501 tatcgtgacc aacgaccaca tgacacttgg tgttggtcca ggtcaaacca accgtgtggc
    13561 ttctgttcgc cttgccattg accaagccaa agatcgtctg gacggggcgg tccttgcttc
    13621 agatgccttc ttcccatttg cggataacgt ggaagaaatc gccaaagcag gaattaaggc
    13681 catcatccag cccggtggct ctgtccgtga ccaagaatcc atcgaagcag cggataaata
    13741 cggcttgact atggtcttta caggtgtgag acattttaga cattaagaag ataaaaggga
    13801 agaaaacagt ttctttcctt ttttggctta aaatgctaac tgaaacaaga ttaaaacgaa
    13861 cttttttgat ataatgttgg taaataattc gcaaaagagg ttgaggaatg aaactgcttg
    13921 ttgtcggttc tggtggtcgt gagcatgcga ttgctaaaaa gttacttgaa tcaaaagacg
    13981 tggaaaaagt ctttgtagct cctgggaatg atgggatgac tctggatggt ttggaattgg
    14041 taaatatctc tatttccgaa cattctaaat tgattgactt cgcaaagacc aatgatgttg
    14101 cttggacctt tatcggtcca gatgatgccc ttgctgctgg catcgtggat gattttaacc
    14161 aagctggact taaggccttt ggtccgacta gggctgcagc ggagctggag tggtccaagg
    14221 atttcgccaa ggaaatcatg gtcaaatacg gcgttccgac agcaatatat ggcacatttt
    14281 cagatttcga ggaagccaag gcctatatcg aaaagcatgg tgcgcctatc gtagtcaagg
    14341 cggatggctt ggcacttggg aagggtgtcg tcgttgctga gacggttgag caagcggtcg
    14401 aagccgctca tgagatgctt ttggacaata aatttggtga ctcaggtgcg cgcgtggtta
    14461 ttgaggaatt ccttgaagga gaggaatttt cactctttgc ctttgtcaat ggtgataagt
    14521 tctacatcat gccaacggct caggaccaca aacgtgccta tgatggcgac aaagggccta
    14581 acacgggtgg tatgggtgcc tatgcgccag ttccacactt accacagagt gtagttgata
    14641 cagcggttga caccattgtc aagccagttc tagaaggggt gattaaagaa ggtcgtcctt
    14701 atctgggagt tctttacgca gggcttatcc tgacagctga tggaccgaag gtcatcgagt
    14761 tcaacgctcg gttcggagat ccagaaactc agcttatctt gcctcgctta acctctgact
    14821 ttgctcaaaa tatcacagat atcctggata gcaaggagcc aaatatcacg tggacggaca
    14881 agggtgtgac tctgggtgtg gttgtcgcat ccaagggcta cccgctagat tattcaaagg
    14941 gtgttgagtt gccagtcaaa accgatggcg acatcattac ctactatgca ggggctaagt
    15001 ttgcggaaaa tagcagagca ctgctctcaa acggcggacg agtttatatg ctcgttacca
    15061 cagcagatac cgtcaaagaa gcccaagcca gcatctacca agaactatcc caacaaaaaa
    15121 tagaaggact cttctaccga acagatatcg gaagcaaggc aattaagtaa agatataaga
    15181 ataacgcgcc gtagtcgcca aacacgataa tggtcgtcgt ggtgaaaaga ccagaacagt
    15241 gaatgttctg gtcaggggga aacttggaga ccgtaggctc aaagtttagg aatgaaaccg
    15301 aaggtttgct tccgcctcca tcacctaaga ccattatcaa aaagaaaaat aaaaattcac
    15361 aaaatacgtt aatggtcgta tggtttgcga gcgttagcga gctaatatag aataatcacc
    15421 gccgttgtga aagaacgatt ggatgacaat ccaatcgttc agggaaattg gaagaccttg
    15481 ggtttccaat ttaggcatga gacacctttg gtggctgctg ccgtccctca caagctaagg
    15541 tgattgttga aaaagaggaa aaaggagaag aaatgaaacc agtaatttcc atcatcatgg
    15601 gctcaaaatc cgactgggca accatgcaaa aaacagcaga agtcctagac cgcttcggtg
    15661 tagcctacga aaagaaagtt gtttccgcac accgtacacc agacctcatg ttcaaacatg
    15721 cagaagaagc ccgtagtcgt ggcatcaaga tcatcatcgc aggtgctggt ggcgcagcgc
    15781 atttgccagg catggtagct gccaaaacaa cccttccagt cattggtgtg ccagtcaagt
    15841 ctcgtgctct tagtggagtg gattcactct attctatcgt tcagatgccg ggtggggtgc
    15901 ctgttgcgac catggctatc ggtgaagctg gagcgactaa cgcagctctc tttgccctcc
    15961 gtctcctctc tgtagaagat aagtccattg cggatgcact tgccaacttt gctgaagaac
    16021 aaggaaaaat cgcagaggag tcgtcaaatg agctcatcta aaacaatcgg aattatcggt
    16081 ggcggtcaac tgggtcagat gatggccatt tctgctatct acatgggcca caaggttatc
    16141 gcgctggatc ctgcggcgga ttgcccggcc tctcgcgtgg cggaaatcat tgtggcacct
    16201 tataacgatg tggacgccct ccgtcagttg gcagaccgtt gcgatgtcct cacttacgag
    16261 tttgaaaatg tcgacgctga cggtttggat gccgttatca aggatggaca actccctcaa
    16321 ggaacagatc tgctccgcat ttcgcaaaat cgtatttttg aaaaggactt tttgtcaaac
    16381 aaggctcaag tcactgtggc accctacaag gtcgtgactt ctagcctaga cttggcagat
    16441 atcgacttgt cgaaaaacta tgtcctcaag actgcgactg gtggctacga tggtcatgga
    16501 caaaaggtta ttcgttcaga agtagacttg gaagcagcct atgcgctagc agactcagca
    16561 gactgcgtct tggaagaatt tgtcaacttt gaccttgaga tttctgtcat cgtgtcagga
    16621 aatggcaagg aggtgacgtt tttcccagtt caggaaaata tccaccgcaa caatatcctg
    16681 tctaagacca tcgtaccagc ccgcatttct gaaagtctag tagacaaggc taaagctatg
    16741 gcagtgcgaa tcgcagaaca actcaacttg tctggaactc tctgtgtgga aatgtttgcg
    16801 actgatgatg acgttattgt caatgaaatc gccccacgac cacataactc tgggcactat
    16861 tctattgaag cctgtgattt ctctcagttt gacacccata ttctcggtgt tctcggagca
    16921 ccattaccag tcatcaaact ccatgcgcca gccgttatgc ttaatgtcct cggtcagcat
    16981 gtcgaggctg ctgagcaata tgtgacagaa aattcaagcg cccacctcca catgtatggt
    17041 aaaatagaag cgaagcacaa ccgcaagatg ggacatgtga ccttgtttag tgatgtaccg
    17101 gatagtgtgg atgagcttgg ggaagggatt gatttttagg acaagtctat gatacaaatt
    17161 atcgttaata catttattga aaaggataag actggagcag ttgttgaagt gttgtatgcc
    17221 agtgctgacc aagataaggt acaagctaaa tatgaagaac tagctgcaca ataccccgaa
    17281 aattatttag ctatctatga tgtaccgctg gatacggatt tgaatacact agatcattac
    17341 ccgtctgtgt ttattgaaaa agaggagttt gagtagaaat cttggtttac ctagatagct
    17401 tattcccaac agcttaagaa gaaaggaaaa attaacacat gatcaaccgt tactctcgcc
    17461 ctgagatggc gaatatttgg agtgaagaaa ataaataccg tgcttggctt gaggtggaaa
    17521 tcctctctga cgaggcatgg gctgagttgg gggaaatccc taaggaagat gtggctttga
    17581 ttcgcaagaa ggcggacttt gacatcgacc gtattttgga aattgagcag gagacgcgcc
    17641 acgatgtggt ggctttcacg cgtgcggttt ctgagactct tggtgaagag cgcaagtggg
    17701 ttcactatgg gttaacttct accgacgtgg tggatactgc ttatggttac ctctacaagc
    17761 aggccaacga catcatccgt cgtgaccttg aaaacttcac taatatcatc gctgacaagg
    17821 ccaaggagca caagttcacc atcatgatgg ggcgtactca tggtgtgcac gctgagccga
    17881 caacctttgg tcttaaattg gcaacttggt acagcgaaat gaaacgcaat atcgagcgtt
    17941 tcgagcatgc agctgctggt gtagaagctg gtaagatttc tggtgcggtt gggaactttg
    18001 ccaatatccc accatttgta gaggagtatg tctgcgataa acttggcatc cgtgcccaag
    18061 aaatctctac acaagtcctt cctcgtgacc ttcacgctga gtactttgcg gttcttgcca
    18121 gcattgcgac ttcaatcgaa cgtatggcga ctgagattcg tggtctacaa aaatctgagc
    18181 aacgcgaagt agaagagttc tttgctaaag ggcaaaaagg gtcttcagca atgcctcaca
    18241 aacgcaaccc aatcggttct gaaaatatga ctggtctggc gcgtgtcatt cgtggtcaca
    18301 tgattacggc ttatgaaaac gtcgctctct ggcacgaacg cgatatttct cactcatcag
    18361 ctgagcgtat catcacacca gatacgacca ttttgattga ctacatgctc aaccgttttg
    18421 gaaatatcgt caagaacttg acagtcttcc cagaaaatat gatccgaaac atgaactcga
    18481 cttttggtct tatctttagc caacgggcta tgttgacatt gattgaaaaa ggcatgaccc
    18541 gtgagcaagc ctatgacttg gtgcaaccaa aaacagccta ctcttgggac aaccaagtag
    18601 actttaaacc acttcttgag gcagattcag aagtaacatc acgtctcact caagaagaaa
    18661 tcgatgaaat cttcaaccca gtttattaca ccaaacgagt ggatgatatc tttgaacgtc
    18721 ttggactagg tgattaatta aaaaataaac agcgagcttc aatctcgctg tttatttttt
    18781 atcgaaaaga cttagtcttc ttttctttta gtgagtccat aggctgctag tgtggccatg
    18841 agtcctgcga ctactagtcc tgcagaatcg tgagttcctg tttcaggaag ttttttctct
    18901 attaccacag gagctggatc ttgaggaaga gctttgcttt cctcagcagg agcagttgat
    18961 ggagctggtt ggcttgggat ttctagtttt ggtttttctt cagcaatagc ggcttgtccg
    19021 ttttcatcgc ctacatgtgt taccatagtt ccgacttcga ctatttgagt aacggcttcc
    19081 tgtgctacga cactatttac aagtgttttc acttccttac catcggcaga agtgctcaca
    19141 gagtagaagt tgctacgatg tccattgacg cccttagtaa tgacttgtgt ttttcctttg
    19201 agtaagagtg gattttcacg agtcactgtg gtaaatggaa tttcttcttc ttggatatcc
    19261 agtctaggtt ttacctcagt agttggtgca agaccacttt catcaccctt gtgagttaca
    19321 ggagcgccaa cttcaaccac ttggtttata acttctttgg ttacctggct atcaaggact
    19381 gtttctgttg tttttccatt ttcagtgagt acagagatgt aatgagttcg ttcacctttg
    19441 actcctgctg tgataatatt ttcctgacca gctgggaggt taggattttc tttcttgata
    19501 acttcaaatg gaatttcttc agttcttgtg atgagttctg gtctggtttc aacattggca
    19561 gccacttcat tttcatccag gcttcctgaa tgagttgcag ctggtttgag gccttgaaga
    19621 gcggctttta ggttggctac aagtgtgtca agctcagctt gtttattacg gttgaggttg
    19681 taatttagag ctgttttagc tgcgtcaagg gcctcaagac tttctttact atatccttct
    19741 aagtttgtag gaattttagc taattcttcg cggagagcat tataattagc acggaagtag
    19801 tctttgttgt ggtctgcaaa ggcagtcatg agttcaaaga tttcctcttc cttgtactca
    19861 gcgcttggtc tatctgccca gattgaaagc atacttccga ctgttggaag atctacttca
    19921 ggatatttgg tagaagctag ttgattgaat ggtgtttttc cagtattctc aatagctttc
    19981 ttgaggaaac caccaccatc ttctggtttt tgaccaagaa tgtagtacca gtcaccgttg
    20041 gtattcaaga atttatagcc tttgcttgct aggtattgag gtgatgcgag gttatatccc
    20101 caccagcctt tagaccagta agaaatcaag acatctttgt caaactgaac atcgtccttg
    20161 tcttcatagt agaagccatc gttgaaggcc attggttgaa gccctctttc tttggccata
    20221 gctgcgaggg tgttggcata ttcggcaaat ttgccataga gttgatacca cttgaggtag
    20281 taccagcctt gggcactagt cgcatcgttg gcgtattcgt cagtaccaaa gttgaaaatc
    20341 tttgttttac ctgcaaagaa gtccatgtat ttaccgatga gggcttttac aaagttcatc
    20401 gcttcttcgt ttttcaagtc catagttgtt tttgaaactt tatcaaagtg ggcttgagga
    20461 tttttaatac ctaatttttc catggcaacc agcatagcat ccatgtgacc tggactgtta
    20521 atagctggga tgagaccgat gtccttagat ttagcgtatt caattagctc tgtcacttct
    20581 gcctgtgtta gtgtagtacc gtttggatcg tcgtagtaag ctttagttcc ttcgataata
    20641 gcttttttaa cgtcatcact agcataggtt tttccgttgg cagtaatggt catatcatcg
    20701 agtagaaagc gaagtccgtc atttcctaga aggagatgga catcagaata tccgagttca
    20761 ctggccttgt ctacgatgcg tttgagctgg ttcagagtaa agtatttgcg tccagcatcg
    20821 attgagatta ccttgttttt ggcaagtttt tcaacctcac gtttagcttc ttcttctttt
    20881 tgagcttcag gcgtgagggt caagttgttg acagtttctt gaagtctagc aatggcttga
    20941 tcaatcgtat cttgttgggc acggctaagg ttgctatcga gagagcgaat agctttttca
    21001 gcttctttta cggccgcgac gctttctgca gtataacggt tcaggtcttt tggtacctcg
    21061 ttaagtgttt gctctgcaga ttcataatca gctgcgaagt attcagcgtt ggcatttgca
    21121 aaatgacgca tgagtttgaa gaggcgtgat ggtgaataac gtgcagatgg agtgtcagcc
    21181 caagcagcta ccataccacc gatgattggg atatcagctc cttctgtttt tggtacagaa
    21241 gtgattggtg tgtttttaat accattgagc ccctgatcga gattgtacca gccttggcca
    21301 tcagcgtttc gtccaagaac gtagtaccaa gcatcattgg tattaaggat ttggtgacct
    21361 ttttcagcta gtagtttaga agaagcgaca tcgtagcctc cccaaccacc agtccacata
    21421 gaaacgatga tgtctttgtc aaaactacca aagcttgtgt cgctattgta gtagataccg
    21481 tcgttaaaag ccattggttt gagaccgtgc gattttacaa tacgagcgag gtcattggcg
    21541 taggcaataa atttttcata gccttttaca gggtagcctt cgtttggata gtatttatca
    21601 gcttgaagca cactccaacc tttagcatct gtcgcatcat tggcatattc atcaagtccg
    21661 atgttgaaga tttcagtctt tttcgcgaaa taagcagcat acttgtcgat aagggctttt
    21721 gtaaaagcga cagcttgttc gttgtcaaga ttgacagtac gggctgattc cttcccaaaa
    21781 tagctaaagt tagggttttg gattcccaat tctttcatgg cattgagaat cgcatccatg
    21841 tgaccaggac tatttactgt cggaatgaga ccgatacctt tatctttggc atagttaatc
    21901 agatctgtca tttgactttc tgttaagtga ttgccgtttg gatcgttgta ataattattt
    21961 gtaccttttt caatggcgcg tttgacatcg tcactggcat aggtcttgcc gttagctgtg
    22021 atgctcatat cgtccaacat gaaacggagt ccatcatttc cgactaatag gtgtaaatca
    22081 gtgtagccat aatgtttcgc tttatcgatg atttccttga gctgttctgg tgagaaatat
    22141 ttacgtccag catcaataga aacaattttc tttttcgcta gtttttcatt tacagttgca
    22201 gcacgttcct ttcctgcctc tgtttccggt ttgtcagcct ctgctttcgc ttcatctttt
    22261 ttagctggtt tatccttgtc agtcttgtct gtatttgact ctttagaatc aacctctttc
    22321 gcttcttcct ttttagggct agcttcttct gcctttttat tagcagtttc tttttcagca
    22381 gaagttggag ttaccacctc tgctttatca ctaggagttg aactaacttc ctcttgtggt
    22441 ttttcttctg tttttggaag actagctacc ttatcagtag ctggagtttc tgtttctaca
    22501 gtttttggag cttctggttg aagctctgct ttaggtgttt cctcagtccg attttcggat
    22561 gattgagggg aatcagaaac tgtatggatg gtcggttggt tttctgtagt agtagtaact
    22621 ccatcggctg caacagtctg tgcttggaag gcaaatccaa ttagaacaga agctgctcct
    22681 acagcgtatt tacgaataga aaaacgctgt tgtttttcat gtttcattgc aaaacctcct
    22741 gattgcattg ttatattgat agcgattata taaatcaacg cccttatttt atttcttata
    22801 ttaacgagag tcaagaggag atgacaaaaa actataataa gtataaaaaa atataaaatt
    22861 taaacttaag atttcagatt ggtcggaaaa aatgcatata tatatctaat ataatttttg
    22921 gttctatttc tataaaatat tccacaaatt atagaatctt ccaaaaacag gtaagcgcta
    22981 cctttttggt gtggtataat aagcatagaa aaagcccaag cgattagctc aggctttctt
    23041 cttagtgatc acggtcacat gagatgaatt taatcttgta gtaatcagat cgtttgtaag
    23101 tttcactgta ttctaaaact tggccagttg attcgagttt ggtgatttta gtttgtagga
    23161 cagtagggaa ttgttcatcg actccgagga ctgaagccgc atgttctgga gttggaaaga
    23221 ctatttcgtt gatttcttca aagtgttcat cattcatgtg aatgtggtag tctaacttga
    23281 aacgattata gatagaacta tagtattcaa ggtttggata atttgcgttg atatattgtt
    23341 ctgggatgta ggatgtatgg tagatataaa cgacaccgtt tgattcgcgg atacgttcaa
    23401 tcttgtagta gaattgatcg ccgcgtagac ccaatttttc caagtaaaca agcttgtttc
    23461 cgcgttcaat tgaaagaaca gttaccttat catctttagc attgaagagt tcaatatctg
    23521 aaaactctac aagcttgtgt ttgcgtgcac gtgaaacgaa ggttcctttt ccttgttggc
    23581 ggacaatata gccatctttg gcaaggtcgt ttaaggcgcg aacaactgtg atagagctga
    23641 catcgtacat tgaaatgagt tctgcttcag tgtaaaattt atctccactg ctaaactgcc
    23701 cagagatgat tttatttttt aattcgtctt ttatgtattg atatttggga attgccatat
    23761 ttttacctct attttccttc tccatagaaa attttaccat aaaagcgaaa aaaatagtag
    23821 tcttttgaat aaaaaattag aataatagtt tgaaaaatta agcgatatag ggattgctca
    23881 tattttatca atgtattcta tacaaaatta ttttaggtcc tatattccga atttaaagag
    23941 cgtttgaaat gggtctaaaa atgtttgaaa ctaattgaat gtgtgtataa tagtaaaaat
    24001 gcagtaaata tcccgacaat ttctattgac aattcaaaca gattggttta taattaatat
    24061 aacaacaaat gaaagcgcaa actttcgcgg tcggaaggta gttttatgac acgatttgag
    24121 atacgagatg atttctatct cgagggaaaa tcatttaaga ttttatctgg tgccattcat
    24181 tattttaggg ttcctccaga ggattggtat cattcgctct ataacttgaa ggctcttggt
    24241 tttaatacgg tagagactta tgttgcttgg aatttacacg agcctcgtga aggtgagttt
    24301 cattttgaag gtgatctgga tttagagaaa tttctccaaa tagcgcagga tttgggtctc
    24361 tacgcaattg tgcgtccgtc tccatttatc tgtgcggaat gggaattcgg tggcttacca
    24421 gcttggctct tgaccaagaa catgcgaatt cgctcatccg acccagcata tatcgaggca
    24481 gttggtcgct actatgatca gttattgcca agactggtgc ctcgtttgtt ggacaatggt
    24541 ggcaatattc tcatgatgca ggttgaaaat gagtatggtt cttacggaga agataaggct
    24601 tacctgagag cgattcgaca gctaatggaa gagtgtggcg taacctgtcc cctctttaca
    24661 tcagatggtc catggcgagc tactctgaaa gctggaacct taattgaaga ggacctcttt
    24721 gtaacaggaa actttggttc taaggcacct tacaactttt cgcagatgca ggaattcttt
    24781 gatgaacatg gtaagaaatg gccactcatg tgtatggagt tctgggatgg ttggttcaat
    24841 cgctggaaag aaccgattat cacacgggat cctaaggaat tggcagatgc agttcgagag
    24901 gttttggaac aaggctctat caatctttac atgttccacg gtggtacaaa ctttggtttc
    24961 atgaatggtt gctcagctcg aggaactttg gacctgccac aagttacatc ttatgattac
    25021 gatgcccttc tggatgaaga aggaaatcca actgctaaat atcttgcagt caagaagatg
    25081 atggcaacac atttttcaga gtatccgcag ttggaaccac tctacaaaga gagtatggag
    25141 ttggatgcta ttccactagt tgaaaaagtt tctttgtttg aaaccttaga tagcttgtca
    25201 agtcctgtag aaagtctcta tcctcaaaag atggaggagc tgggacaaag ttatggctac
    25261 ctactttatc gaacagaaac aaactgggat gcagaagaag aaagacttcg tatcattgat
    25321 ggtcgagata gggcccagct gtatgtcgat ggtcagtggg ttaaaactca atatcagaca
    25381 gagattgggg aagatatttt ttatcaaggt aaaaagaaag ggctatctag gttagatatc
    25441 ttgatagaaa atatggggcg tgtcaactat gggcataagt tcttagcgga tacgcaacgt
    25501 aagggaattc ggacaggggt ctgtaaggat ctgcatttct tactaaactg gaaacactat
    25561 ccactcccac tagacaatcc tgagaaaatt gatttttcaa aaggatggac tcaaggacaa
    25621 ccagcctttt acgcttatga ctttacagtc gaagagccaa aagatactta cctagacttg
    25681 tctgagtttg gtaagggagt tgcctttgtc aatgggcaga atctaggacg tttttggaac
    25741 gttggcccaa ctctctcact ttatatccct catagctatc tcaaggaagg tgccaaccgt
    25801 atcattatct ttgaaacaga aggtcaatat aaagaagaga ttcatttaac tcgtaaacct
    25861 acactaaaac atataaaggg ggaaaactta tgacaattgt aggatgccgt attgatggac
    25921 gtttgatcca cggacaagta gccaatcttt gggctggaaa actaaatgtt tcacgcatta
    25981 tggttgtaga cgacgaagtt gtcaacaacg atattgaaaa gagtggtttg aaacttgcga
    26041 caccaccagg tgtgaaattg agtattttgc cagttgagaa agctgcagcc aatattcttg
    26101 ctggcaaata cgatagccaa cgtctcttta tcgtggctcg taaaccagac cgcttccttg
    26161 gtttggtaga agcaggtgta ccacttgaaa cccttaatgt tgggaatatg tctcaaacac
    26221 cagaaactcg ttctattaca cgttctatca acgtagtaga caaggatgtg gaagacttcc
    26281 acaaactggc agaaaaaggt gttaaactta ctgctcagat ggttccaaat gatccaattt
    26341 cagacttttt gagcttatta aaataggaaa aaaattttta ggaggtcatt gttatgatac
    26401 aatggtggca aattttactt ctcactttgt actcagctta tcaaatctgt gatgagttga
    26461 cgatcgtttc atctgcaggt tcccctgtat ttgctggttt cattactggt ttaatcatgg
    26521 gagatgtgac tactggttta cttatcggtg gtaacttgca actgttcgtt cttggggttg
    26581 gtaccttcgg tggtgcttct cgtatcgacg caacttctgg tgcggttctt gcgacagcct
    26641 tctctgtttc acaaggaatt gatgcaccgc ttgccattac tacaatcgct gtaccagtag
    26701 cagctctctt gacttacttc gacgttcttg gtcgtatgac tactaccttc ttcgctcacc
    26761 gtgtggatgc tgcaatcgaa cgctttgact ataaaggtat tgaacgcaac tacttgcttg
    26821 gtgcgattcc gtgggctcta tctcgtgccc ttccagtctt ctttgccctt gcttttggtg
    26881 gtgcctttgt acaatcagta gtagacttcg ttgaagccta caaatgggtt gcagatggct
    26941 tgacacttgc aggacgtatg cttccaggtc ttggatttgc aatcttgctt cgttaccttc
    27001 cagttaaacg taaccttcac taccttgcta tgggatttgg tttgacagct atgttgactg
    27061 ttctttactc atatgtaaca ggtcttggtg gcgctgttgc tggtatcgta ggtactcttc
    27121 ctgctgaagt tgctgaaaaa attggtttcg tgaacaactt caaaggtttg tctatgattg
    27181 gtatttctat cgtaggtatt ttccttgcag tgcttcactt caaaaatagc caaaaagtag
    27241 ctgtagcagc accttctaca ccatcagaaa gtggggaaat cgaagatgac gaattctaat
    27301 tacaaactta caaaagaaga ttttaatcaa atcaacaaac gtagcttgtt tactttccaa
    27361 ttaggttgga attacgaacg tatgcaagct tctggttacc tttacatgat cttgcctcag
    27421 ttgcgtaaaa tgtatggtga tggaactcct gaattgaaag aaatgatgaa agttcatact
    27481 caattcttca atacttcacc attcttccat accattatcg ctggttttga ccttgccatg
    27541 gaagaaaaag atggtgtagg ttcaaaagac gccgttaacg gtatcaagac aggtttgatg
    27601 ggaccattcg ctcctcttgg ggatacaatc tttggttcac ttgtacctgc tatcatgggg
    27661 tcagtcgcag caactatggc tatcgctggc caaccttggg ggatcttcct ttggattgca
    27721 gttgcagtag cgtatgacat cttccgttgg aaacagttgg aatttgctta caaagaaggg
    27781 gttaacctta tcaacaacat gcaaagtacc ttgacagctt tgattgacgc tgcatctgta
    27841 cttggtgtct tcatgatggg tgctcttgta gcaacagtga ttaactttga aatttcttac
    27901 aagttgccaa tcggtgaaaa gatgattgat ttccaagaca tcttgaacca aatcttccca
    27961 cgtttgcttc cagcaatctt tactgccttt atcttctggt tgcttggtaa gaaaggtatg
    28021 aactctacta aagctatcgg tattattatc gtacttgctt tggctctttc tgcccttggt
    28081 cactttgcac ttggaatgta attccttatg actaaatcat taattttggt gagccatggt
    28141 cgcttctgtg aggagcttag aggtagcaca gaaatgatta tgggcccaca agacaacatt
    28201 tacacagtag ctcttcttcc agaagatggc ccagaagaat ttactgctaa atttgaagct
    28261 gttattggag gattggatga tttcctagtc tttgcggatc ttctcggtgg gacaccttgt
    28321 aatgtggtga gtcgcttgat catggaaggt cgtgatattg acctttacgc agggatgaat
    28381 cttccaatgg tgattgaatt tatcaatgcg agccttacag gcgcagatgc ggactacaag
    28441 agccgtgctg cagaaagcat tgtgaaagtt aatgacctgt tagcgggctt cgatgatgac
    28501 gaagatgaat aatactcttc gaaaatctct tcaaactacg tcaacgtcgc cttgccgtag
    28561 gtatatgtta ctgacttcgt cagtcttatc cggcaacctc aaaacggtgt tttgagctga
    28621 cttcgtcagt tctatctgca acctcaaagc agtgctttga gcagcctgcg gctagtttcc
    28681 tattttagtt ggaactcgat tcaattcatg tgacaacgtg aaaatcgtta gagcatttta
    28741 tatagaatat acatgggaat ggagcttact cccattccca tatttaatag aaaaagagga
    28801 actcaatgct acattataca aaagaagact tgctcgaatt gggtgcagaa atcactacgc
    28861 gtgaaatcta ccaacagcct gatgtatgga gagaagcttt tgaattttat caagcaaaac
    28921 gtgaagaaat tgcagccttc ctacaagaaa tcgctgataa acatgactat attaaggtta
    28981 tcttgacagg tgctgggact tctgcttatg tgggagatac cttgctacct tactttaagg
    29041 aagtctatga cgaacgcaaa tggaatttca atgctattgc gacaacagat atcgttgcca
    29101 atccagcaac ctatttgaaa aaagatgtgg caactgtcct tgtgtctttt gctcgtagtg
    29161 ggaactcgcc tgaaagtgtg gcgactgttg atttggccaa atccttggtg gatgagcttt
    29221 atcaagtgac gattacttgt gcagcagatg gtaaattggc tcttcaagct cacggtgatg
    29281 accgtaatct cttgctcttg caaccagctg tctctaatga tgctggattt gccatgactt
    29341 ctagctttac gtctatgatg ttgacagctc tcttggtctt tgatcctaca gaatttgctg
    29401 ttaagtctga acgttttgaa gttgtatcta gtcttgcccg taaagtttta gacaaggcag
    29461 aagatgtcaa agagctcgtt gatttagact ttaaccgtgt catctatcta ggcgctggtc
    29521 ctttctttgg acttgctcat gaagctcagc tcaagatttt ggaattaact gctggtcaag
    29581 ttgcgaccat gtatgaaagc ccagttggct tccgtcacgg tccaaaatct cttatcaacg
    29641 acaatacagt tgttttggtc tttggtacaa cgacggacta cactcgtaag tacgacttgg
    29701 acttggttcg tgaagttgct ggtgaccaga ttgctcgtcg tgttgtgctt ttgagtgatc
    29761 aagcttttgg tcttgaaaat gtcaaagaag tggcccttgg ttgtggcggt gtcttgaatg
    29821 atatttaccg tgtcttccct tacatcgttt atgcccaact ctttgcccta ttgacttcac
    29881 tcaaggtaga aaataaacca gatacaccgt ctcctacagg tacagtaaac cgtgtagtac
    29941 aaggtgtcat aattcacgaa tatcaaaagt aagacagtgt ttatgaattc ttgacaagag
    30001 gatttgtaaa ttatcagata aaccatagat tgtcagtacg ctttctatgg tttgtttgct
    30061 tgagagaaat agtaaaagga gaacagaatg aaagcataca cagagcgtgt atttggaaat
    30121 gttgagggtg aggatgtctt ggcctatcga tttgagacag acggtggcta ccaacttgag
    30181 gttatgactt atggtgcgac tatcttgcgc tatgtcgcac ctgacaaggc tggaaatttt
    30241 gccaatgtta tcttgggatt tgatgacttt gatagttatg taggcaatag tcccaagcat
    30301 ggagcaagtg taggtcctgt agcgggtcgt attgcaggtg cgacctttga gctcaatggt
    30361 aagacctatg accttgaggt taataatgct agcaactgta atcacagtgg ttcaactggt
    30421 tgggattcca gcttgtttga agttgaagaa gtaagcgatc atggcttgac tctctacaca
    30481 gagcgtacag atgggacagg agggttccct ggaaatctca agatttggat cagttatcac
    30541 ttggaagaaa ctggtgccta tgaaatcagc tacaaggtaa cgaccgatca ggatacgctg
    30601 gtcaatccaa ccaaccacag ctatttcaac ttgtctggtg atttcacgca gacgattgac
    30661 cgtcatgtct tccaactaaa cacagagggc atttactcaa tcgctcctga cggtgttcct
    30721 gccaaaactc cagaagccaa ccgtgatgtg gtcaaacaca tctacaatgg tgccttgttg
    30781 aaggatatct ttgcagaaga agatgagcaa atccagctgg catcaggttt ggatcaccca
    30841 tttgcccttc ctgtaggcca tgacaatgct ggattccttt atgaccaaaa ttcaggtcgc
    30901 ttcctgcttt tcaagacaga agctccttgc tttgtggtct acacagcaaa ctttgtggat
    30961 gaaagtgtca tcataggagg tcagccaatg ctacagcaca atgggattgc tcttgaagcg
    31021 caagctttac cagatgccat tcacagtgac cttaaaggcc aagtcattct taaagctggt
    31081 caaaccttca ccagtaagac acgttatgaa cttgttgtga aataaaaaag ctggtcaaaa
    31141 agtctttaaa attaaaataa cgcatattgt caggtgatga aaagtttgat aatatgcgtt
    31201 ttattatgaa atgatttact ttatcttatc ctgaaatggt gttatttttg agttatctgg
    31261 cttgactttc ttgatggaaa ttatataata gttgtaataa caataattac aacgagaaaa
    31321 gaggaccatt tatgacctat gaatacaaga gtcacattta tttggcagag acagttttaa
    31381 atgtaaagga tttggccagt caaacagcct tttatcagca agttatcggt ttagaaatct
    31441 tatctcaaac tgagacagag tccattctag gccttggtgg aaaagtcttg gtacagctga
    31501 ttcaagcaca agagagcgga gaagtgaggg aacattatgg tctttaccat ttggccattc
    31561 tcttgcccac acgcaaggct ttggctgatg tcttgaaaca cctgacagat ttacaaattc
    31621 ctcttgtcgg cggtgcagac catggttaca gtgaagctat ttacttggaa gatttggagg
    31681 gaaatggcat tgaactctat cgagataagc cagtttccac atgggatatt cgagaagatg
    31741 gacgcattat cggagtgacg gaggctcttg cggcgcagga catttatgag ttgggggaaa
    31801 gagtagagcc ctttatcctg gcagaaggta caagaatggg gcatattcat ctttccgtca
    31861 aggatagtcg aaagtccagc cagttttatc aaaaggtgtt agggctagag gataaattca
    31921 gtgtgcctgg cgctagttgg attgcggctg gagattacca tcatcattta gcagttaacg
    31981 aatggggagg aaaaggtctg gcttcgcgta agcaaggctt accaggttta gcctactatg
    32041 tcatcgaagt cgcacataaa gaagaactgt taacgattgc ccagcgagca caagaagttg
    32101 acgcaccaat caaatggatg acatcgagcc aattggaaat cacagactca gatggcatcg
    32161 tgacctgtat tcgtttagca aggtaaaatt aggaattttt aataagttat aagtattgtt
    32221 agtttgcttt ttgaacggtc tttggtaaca gaactgcgtg agctggatgg gcgagaattt
    32281 tgacaaagaa gctgattaga gatataatga agaaaaatcg agcaaggaaa aagaaatgac
    32341 aaattcaaag tatattactt gtttgaaacg ttcagagggc cagttgtgtg ggattcaaaa
    32401 gatgattgaa ggagatcgtg actgtgctga tattgtgacg caactgacag cagtgagatc
    32461 tagtgtagag cgcgtgattg agatgataat taccgaaaat cttactgaat gtatcaatca
    32521 gccactagat gattctgaag ctcaaaagga acgcctagaa aaggctatcc gatacttgat
    32581 taaacggaaa taaatgaatg ttttgagacg atatgtgcaa aggtctatta actattagaa
    32641 tagtttaatg tgagtcaaaa gaagttgtaa aaaatcttta aaattaaaaa aacgcatagt
    32701 atcaggtgtt gaatgtactg acccccaaaa gttagatttt ttctgtctaa cttttggggt
    32761 gcagttcata agaaccttgg taatatgcgt tttattatgt agagacttat actcttcgaa
    32821 aatctcttca aaccacgtca gcttcacctt gccgtagata tggtt
//
LOCUS       DAVHBD010000025        32723 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000025 DAVHBD010000000
VERSION     DAVHBD010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32723
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.025"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(82..1209)
                     /locus_tag="VVK04_001197"
     CDS             complement(82..1209)
                     /locus_tag="VVK04_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU3989855.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(1351..1731)
                     /locus_tag="VVK04_001198"
     CDS             complement(1351..1731)
                     /locus_tag="VVK04_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEU3989856.1"
                     /translation="MTIEELVDSHGVTLAYFDNELWQRPGVYIKEISIIFINRELSEN
                     AKKRVIYHELGHLEHSTALYKNNHTRCENEANRHMIHKLLEEELALSDDHQSFNYIQF
                     MQKHELRTVTDELMVIDEYYELIG"
     gene            complement(1752..2114)
                     /locus_tag="VVK04_001199"
     CDS             complement(1752..2114)
                     /locus_tag="VVK04_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989857.1"
                     /translation="MLSEENIMSQDTYSKSEIDLKLDKINSDTQHGFEKIDLKVDQLR
                     QEMRSGFEKIDLKFEQVDLKFDNFEKRVETMFLTQENKRLEEQAKSKKEFMYWFIGLL
                     VSTLLGILAIIVTILTTK"
     gene            complement(2235..2657)
                     /locus_tag="VVK04_001200"
     CDS             complement(2235..2657)
                     /locus_tag="VVK04_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989858.1"
                     /translation="MTNIPMKKNPFREKMTAISIVNPETAQLLGTITNFDMFPGSTSL
                     VAFLDFFNLRPETDYILSLTAHFPNGTSYPVHATRINIARQEFVLLEDGFGMATGNFS
                     FNFTIEKPSDFYFFFVLMDENGQEVDTAYSYHHFGKWG"
     gene            complement(2659..3015)
                     /locus_tag="VVK04_001201"
     CDS             complement(2659..3015)
                     /locus_tag="VVK04_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3989859.1"
                     /translation="MFETFEKIKSLAKKQGISLNTLEDRVGLGKNYIYSLKNKKTPSA
                     EHISKIADYFNVSTDYLLGRTDNPAIAGDDTIAGYTSDDLRKMAENAKTFDGKPLTEE
                     DIDAIQNIIEIYLRGR"
     gene            complement(3432..3671)
                     /locus_tag="VVK04_001202"
     CDS             complement(3432..3671)
                     /locus_tag="VVK04_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989860.1"
                     /translation="MTFKEYLLKASKRDIYDDGKDFDFETIFAREILRYAHDSELETK
                     TGFFRHLEIMNADSWFVELARSIYQDFEKSISDSH"
     gene            3736..3927
                     /locus_tag="VVK04_001203"
     CDS             3736..3927
                     /locus_tag="VVK04_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU3989861.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            complement(4041..4262)
                     /locus_tag="VVK04_001204"
     CDS             complement(4041..4262)
                     /locus_tag="VVK04_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989862.1"
                     /translation="MSKLTKEDVLQVSQDIINDAIPVIKDMLDEVFEKYPIDIEIREA
                     IFYSVLVAHKLSTETTVSLLTQLVNAQEN"
     gene            4380..4523
                     /locus_tag="VVK04_001205"
     CDS             4380..4523
                     /locus_tag="VVK04_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989863.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            4603..4875
                     /locus_tag="VVK04_001206"
     CDS             4603..4875
                     /locus_tag="VVK04_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989864.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            4872..5066
                     /locus_tag="VVK04_001207"
     CDS             4872..5066
                     /locus_tag="VVK04_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989865.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            5063..5254
                     /locus_tag="VVK04_001208"
     CDS             5063..5254
                     /locus_tag="VVK04_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989866.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            5266..5607
                     /locus_tag="VVK04_001209"
     CDS             5266..5607
                     /locus_tag="VVK04_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989867.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDTRREWVDMLTRAAEKETVSNVMRLLIK
                     EANKLMKEVTK"
     gene            5608..5838
                     /locus_tag="VVK04_001210"
     CDS             5608..5838
                     /locus_tag="VVK04_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989868.1"
                     /translation="MVRNKLTDLTNTLFAQLETLDDRDLTADELKTELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            5852..6574
                     /locus_tag="VVK04_001211"
     CDS             5852..6574
                     /locus_tag="VVK04_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEU3989869.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTTYTKTQIGEVRRRLGLPVGKV
                     YQGKLLTKEQHDYLVSIQKNKISRDVANEMNLKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNSGQFKKGNRPLNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEEHHGPIPKGHSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            6567..7049
                     /locus_tag="VVK04_001212"
     CDS             6567..7049
                     /locus_tag="VVK04_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEU3989870.1"
                     /translation="MASLYELTGQFLTVYQMDIDDETKTDTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            7049..7408
                     /locus_tag="VVK04_001213"
     CDS             7049..7408
                     /locus_tag="VVK04_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989871.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            7408..7893
                     /locus_tag="VVK04_001214"
     CDS             7408..7893
                     /locus_tag="VVK04_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989872.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            7856..9049
                     /locus_tag="VVK04_001215"
     CDS             7856..9049
                     /locus_tag="VVK04_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEU3989873.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKDVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFRNYESYISNLPNFFRWEDIEKIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            9068..9385
                     /locus_tag="VVK04_001216"
     CDS             9068..9385
                     /locus_tag="VVK04_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989874.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            9385..10212
                     /locus_tag="VVK04_001217"
     CDS             9385..10212
                     /locus_tag="VVK04_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU3989875.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            10232..10738
                     /locus_tag="VVK04_001218"
     CDS             10232..10738
                     /locus_tag="VVK04_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989876.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDDDDLPF"
     gene            10911..11732
                     /locus_tag="VVK04_001219"
     CDS             10911..11732
                     /locus_tag="VVK04_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEU3989877.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIDFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKDLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            11735..13078
                     /locus_tag="VVK04_001220"
     CDS             11735..13078
                     /locus_tag="VVK04_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU3989878.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            13524..13862
                     /locus_tag="VVK04_001221"
     CDS             13524..13862
                     /locus_tag="VVK04_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989879.1"
                     /translation="MSYDLEILAKIESGDYICIAEPRYSSPTYNLGKMFRVAMDWDFD
                     QGTIYNVADIFENIKRGITELERQPEKYVQYEPANKWGTINDALYVLRSLRDCILEQD
                     IDTKYLYVRW"
     gene            14013..14327
                     /locus_tag="VVK04_001222"
     CDS             14013..14327
                     /locus_tag="VVK04_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989880.1"
                     /translation="MEELKKKVNAVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWIGYSPSMAQVVIAVYLIYG
                     GN"
     gene            14329..14835
                     /locus_tag="VVK04_001223"
     CDS             14329..14835
                     /locus_tag="VVK04_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU3989881.1"
                     /translation="MNKQELIKKLEERRTITGNFQGYVVWWKDVKEIFEQLGEPQPVK
                     VPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLNGYEVEK
                     EKRYFVKIKGNIKENMLVYGEFLKRYFFTKSFSLDDVIYSHTRKELEDANFGWVFDCS
                     GIEIEEVE"
     gene            15140..15535
                     /locus_tag="VVK04_001224"
     CDS             15140..15535
                     /locus_tag="VVK04_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989882.1"
                     /translation="MIPKFRVWHYELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPSIYLKG
                     LLNGYAWTEDEEIIDNVYENPELLEVTHE"
     gene            15528..15707
                     /locus_tag="VVK04_001225"
     CDS             15528..15707
                     /locus_tag="VVK04_001225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989883.1"
                     /translation="MNKRQRKKKILNGLNKEERYHRTHCPVCDSEAGLFDRYFNTYGF
                     CSEYCGYEYYGISRL"
     gene            15728..16042
                     /locus_tag="VVK04_001226"
     CDS             15728..16042
                     /locus_tag="VVK04_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989884.1"
                     /translation="MTLFDEVQQLSSESHAKWFERYFEKYNLEQKLKTSAQKGYTGYL
                     INVWSVRDEYLRNRLGDEITFEALRELLGAGFTVKYKLYLSKNIFTGQDFVSNKKIHI
                     TW"
     gene            16117..16578
                     /locus_tag="VVK04_001227"
     CDS             16117..16578
                     /locus_tag="VVK04_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU3989885.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWSDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLQLGRMINRLKNPKHRTILRMTYINK
                     MYVDDICDSMRGISSPTYYRLKKQAVKELDIILSELIVNDSNCTGMKSKIC"
     gene            16603..16685
                     /locus_tag="VVK04_001228"
     tRNA            16603..16685
                     /locus_tag="VVK04_001228"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16634..16636,aa:Tyr,seq:gta)
     gene            16934..17413
                     /locus_tag="VVK04_001229"
     CDS             16934..17413
                     /locus_tag="VVK04_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEU3989886.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQT
                     LISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            17391..18689
                     /locus_tag="VVK04_001230"
     CDS             17391..18689
                     /locus_tag="VVK04_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEU3989887.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWGNLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITVKATGQKILFRGLDDELKITSITVDIGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            18701..20170
                     /locus_tag="VVK04_001231"
     CDS             18701..20170
                     /locus_tag="VVK04_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU3989888.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITMHSTEGSHLKKLKSYYL
                     GEHAILEHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQNEQVTPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            20079..21716
                     /locus_tag="VVK04_001232"
     CDS             20079..21716
                     /locus_tag="VVK04_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEU3989889.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLNKEI
                     NKIFDKFQRDYDLSQVEARQVLKNMKDKKDLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTDIWKNTGKLTSSIKDELLMSLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKTELVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTEEYLKMK
                     QKLIAEGYKIVKVKNTWPVDGPYKGVNTVIEKDGINFEMQYHTQESFDLKNGSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            21718..21927
                     /locus_tag="VVK04_001233"
     CDS             21718..21927
                     /locus_tag="VVK04_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989890.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            21924..22337
                     /locus_tag="VVK04_001234"
     CDS             21924..22337
                     /locus_tag="VVK04_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU3989891.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLFASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIYYLST"
     gene            22380..22643
                     /locus_tag="VVK04_001235"
     CDS             22380..22643
                     /locus_tag="VVK04_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989892.1"
                     /translation="MKYRKKPVVVEAVQFLDTEESIDELCDFGLDPVRIDYADLKNPL
                     LKIETLEGLMVATEGDYIIKGVQGEFYPCKPDIFAETYEKTEE"
     gene            22645..22896
                     /locus_tag="VVK04_001236"
     CDS             22645..22896
                     /locus_tag="VVK04_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989893.1"
                     /translation="MLEKAKQLASQEFSRLSGREIKAEDCFVVWFSKTLQNWKALVST
                     NAITSSEPCGNYAEITHNGDKNETYVDVYAKVSNRAIKD"
     gene            23099..23608
                     /locus_tag="VVK04_001237"
     CDS             23099..23608
                     /locus_tag="VVK04_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEU3989894.1"
                     /translation="MNEETQTVETVEEQKVPAEPAQQPQDEKKYTDADVDAIIDKKFA
                     KWKSEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAKAMLSE
                     RDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQTVQQEV
                     TEKWRKDFL"
     gene            23631..24656
                     /locus_tag="VVK04_001238"
     CDS             23631..24656
                     /locus_tag="VVK04_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEU3989895.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKKSAQGKTVNRAKAWKTGTTYKEGDTVTHADKVYVAVKDISNSSTAPDTDTTNW
                     KEKTGKK"
     gene            24666..24854
                     /locus_tag="VVK04_001239"
     CDS             24666..24854
                     /locus_tag="VVK04_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989896.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYVELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
     gene            24856..25167
                     /locus_tag="VVK04_001240"
     CDS             24856..25167
                     /locus_tag="VVK04_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEU3989897.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIEVVYGEKGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            25148..25486
                     /locus_tag="VVK04_001241"
     CDS             25148..25486
                     /locus_tag="VVK04_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989898.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVVKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            25461..25976
                     /locus_tag="VVK04_001242"
     CDS             25461..25976
                     /locus_tag="VVK04_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU3989899.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPKGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            25973..26341
                     /locus_tag="VVK04_001243"
     CDS             25973..26341
                     /locus_tag="VVK04_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989900.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            26344..26757
                     /locus_tag="VVK04_001244"
     CDS             26344..26757
                     /locus_tag="VVK04_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU3989901.1"
                     /translation="MLANGITLSYGESKETYTKLVGLKEVPEFGIELEKVENTTLEDK
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVNFEG
                     QVSVKLGGGGVNAVIEFILKIALQSELEFTDGVGG"
     gene            26762..27142
                     /locus_tag="VVK04_001245"
     CDS             26762..27142
                     /locus_tag="VVK04_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989902.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVVE"
     gene            27181..27531
                     /locus_tag="VVK04_001246"
     CDS             27181..27531
                     /locus_tag="VVK04_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989903.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            27518..31051
                     /locus_tag="VVK04_001247"
     CDS             27518..31051
                     /locus_tag="VVK04_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989904.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSAAMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIVTDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERIIRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAKFAHSVATGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTNALSSVSNWFGEMFTNAYNAVKDAFSSIGDFFKGVWDTVKSIFVNAGQMVGE
                     AVGGAFKSAVNAVLGTIENVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARG
                     GIVDSPTIAMIGEAGKEAVVPLENTGFIQTLGRVVSSAVVNAMAGVSPQGGFSGDGDI
                     VIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
     gene            31060..31410
                     /locus_tag="VVK04_001248"
     CDS             31060..31410
                     /locus_tag="VVK04_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989905.1"
                     /translation="MAQLTINGVAVKPPKYFQVGIQDIDGETGRNANGDMMRDRITTK
                     RKLDCEWGMMTQGELSQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            31415..>32723
                     /locus_tag="VVK04_001249"
     CDS             31415..>32723
                     /locus_tag="VVK04_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU3989906.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGDYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKETKHKAEEALRNAGASTLLAQEAKRI"
BASE COUNT        10848 a         5561 c         7348 g         8966 t
ORIGIN      
        1 aaagcaaccc cttgaattat caatatcttc aaggggtttt gttgtgttat gaaatcaaaa
       61 aggggcaatc aaggggcaga attaaaaaat agtatctaat ttattgacca gtttatcctc
      121 catatcttca gtagtatgag aatagatttc caaagtcatt tttgcatttg agtgcccaac
      181 tcgatccatt attgatttta ttgggaggcc agactctgct aaaaacgaaa tatgagaatg
      241 cctaaaaata tggctagata agtttttttc tattttggcc tgttttccat atttttttaa
      301 tatctgtatg aagcaagcta ttgttgtagg ttgattccat ttttcaaaac agaaaatata
      361 atcatcgctt gacaatggct ggaaacgttc gctaagtcgt actatttgtc tttgaatagc
      421 ttctatgaca ctctctgata ctttgattgt ccgtattgaa tttgtagtct ttggtagcgt
      481 cttgattttg tttactgaat caaaattacc tgtgatctca attttgttgt tttcgaagtc
      541 tatattcttc agttgtaagg cagttaactc accatatctc ataccagtta atgtcagcac
      601 aagaaccata tcagcgtact tttggtgata ttctcgacga ttaaggacat cgacaagtgc
      661 ttttatttct tgcatggtga gaaagttgtt acgctttttt tccagttctt ctaaagtctt
      721 tggtttttga ggaatcgtag tataatcgac ctcgttgttt tcaatgtaag agtattgaac
      781 agcgtaatta aagatacctc tgagcctatg ccgtactttt ttagctgtaa tatatccgtt
      841 gctttcaata attttttcaa tagcctcttg aagaaaacgc ctgtcaagat tagcaagtat
      901 ggtatcggat ggtatgactt ccttcatctt cttatcaact gatttacaat tatgttttgt
      961 tgattccttt actgtttgcg cccatgattt ataaaaaagg ttatagattt cttcaaatgt
     1021 aatgctttct acttgttttg tgctaagttt tttatttatc ttctcttgca acaagatagc
     1081 agcttgattt cttgcctggg gagttttctt ctccatggtt actgaaactt tttttaattt
     1141 ctcagtatat ggatctttgt atcgctcaaa aaatttatat ttgccgtttg gtaattcttc
     1201 catccacatt gattttaacc tcactttttg ataaaatggg tatagtaaaa agggcttttt
     1261 aatgcctttt actatactgg atatcctcac actcaaagtt tggcgatggc gagtgtgagg
     1321 attttttgtt tttatagtta ttctgatgaa ctatcctatc aattcataat attcgtcaat
     1381 taccatcaat tcgtctgtga ctgttctaag ctcatgtttt tgcatgaact ggatatagtt
     1441 gaaagattga tggtcgtctg atagtgcaag ttcttcttct agcaacttat gaatcatgtg
     1501 cctattagcc tcattctcgc acctagtgtg gttattttta tatagtgcag tagaatgttc
     1561 cagatgtcct aattcgtggt atatgacccg tttttttgcg ttttcggaca gttcacggtt
     1621 tataaagata atactaatct ctttgatgta aactccaggt ctttgccaaa gttcattatc
     1681 aaagtaagcg agagtgacac cgtgtgagtc tactagctct tcaatagtca taggctatca
     1741 tcctttttgt gttattttgt tgttaaaatg gttacgatga ttgctagtat ccccagtaaa
     1801 gtactaacta acagtccgat aaaccaatac atgaactctt ttttgctttt agcttgctct
     1861 tctaatctct tattctcttg agttagaaac atagtctcta cacgtttctc gaaattatca
     1921 aattttaaat caacttgttc aaattttaag tcgatttttt caaatccgct acgcatttct
     1981 tgtctgagtt gatcaacttt taaatcaatt ttctcgaatc catgctgagt gtcagaatta
     2041 attttatcaa gttttaagtc gatttcagat ttgctgtaag tatcttgtga cataatattt
     2101 tcctccgata acatttctga ctccattata tcatgatttt gtatgggtac agttttcgat
     2161 gaagatttag aagcgtaaag tgaagaaact ttggaagggg taggtttgaa attatcttgt
     2221 gtgtccggca ttgtttaccc ccactttcca aaatgatgat aactatatgc tgtatctact
     2281 tcctgaccgt tttcgtccat caagacgaag aaaaagtaaa aatcgctcgg cttttctatc
     2341 gtaaaattaa agctaaaatt tccagtggcc ataccaaagc cgtcttcaag tagcacaaat
     2401 tcttgtctcg caatatttat tctcgtagca tggacagggt aagacgtgcc attagggaag
     2461 tgggcagtta gagacaagat ataatctgtt tcaggtctta gattaaagaa gtctagaaat
     2521 gcaaccaaag atgtcgaacc aggaaacata tcgaaattgg ttattgttcc tagcaattga
     2581 gctgtttcag gattgacaat actgattgct gtcatctttt ctctgaacgg attcttcttc
     2641 attggaatgt tcgtcatact atctacctct caaataaatc tcaataatgt tctgaatggc
     2701 atcgatgtct tcttctgtaa gtggcttgcc atcgaaggtc ttggcattct ctgccatctt
     2761 tcggaggtcg tcagacgtgt atcctgcgat tgtatcatca ccagcaatag caggattatc
     2821 tgtgcgacca agtaagtagt ctgtagatac attgaagtag tcagcgattt tggatatatg
     2881 ttcagcagat ggagtctttt tatttttaag actgtaaatg taatttttcc ccaaaccaac
     2941 cctatcttct aaagtgttta gagaaattcc ctgtttttta gctaaacttt taattttttc
     3001 gaatgtctca aacattgata catcaacctt tctgaagcat tacaaaaaaa tattttattt
     3061 tttcgcctaa aacacttgac aaaaattaga cgaacaacta aaatagtatt tgtaagtaat
     3121 taacaactaa aaaaacaact aagaaataaa ttataaaaat gtttttgcga acggtattta
     3181 tagatttatt agtgttttta ttatgctttc attttagacg aacatctaaa aaaagtcaag
     3241 cgaaaagata aaaaatagtt acatttttag ttgtttctta tttacaaaat aagtaaaaag
     3301 gaggaacgtg tcgatggtaa gtattcttaa aaatttagaa caagaaaaag accaccttga
     3361 aaaaatcatt aaggtagtca gcgctggtgg taaatttctg agattgccat atcaaaaaaa
     3421 gtcacgctcg attagtgaga atctgaaatt gatttctcaa aatcttgata aattgagcga
     3481 gcaagttcaa caaaccacga atcagcattc atgatttcaa gatgacgaaa gaaacctgtt
     3541 ttggtttcca gttcagaatc gtgtgcataa cgtaatattt ctctagcaaa gatggtttca
     3601 aaatcaaaat ctttaccatc gtcgtagatg tcgcgtttgc ttgctttgag taaatattct
     3661 ttaaaagtca taaggttaac tcctttctgc ttatattata gcagaaaaag aagaaagaaa
     3721 aagaaaggag aaaatatgcc agatatcgca aacggtcgcg aaagagttat tgctttcttg
     3781 aaagagaaag gcattaaaaa agcaactcta gcggttgctt acggctttaa acgacaggaa
     3841 gtgacaaaca ttctaagtgg aacgactaaa ggtccacgag cgaacagttt cattcttcag
     3901 gttattgaag attatgggat tgagtaggaa agatttgagg agtaggaaaa tgagaccaag
     3961 acgatatccg tatagtggga aaaaagagtc cacctttgtg aaggcagacc ctgaattggt
     4021 agaaaagatt ctaagaaaca tcagttttct tgagcattta caagttgtgt tagcaacgaa
     4081 actgtagttt ctgtgctgag tttatgagcg acaagaacgc tatagaaaat agcttctcta
     4141 atctctatgt cgattggata tttttcaaat acttcatcca acatatcttt gataaccgga
     4201 atagcatcgt tgataatgtc ttgagaaact tgtaaaacat cttctttagt taatttagac
     4261 atatagtttt cctcctttct gatggaattt tgactaaaac ggtgagaggt cctagtcaaa
     4321 attattatag caatttagga ggaaattaca tcagtcttga ggctgatata ggaggttgaa
     4381 tggaagataa aatcattgaa cttgctgatt acttcatcag cgaatctaca acgtacagag
     4441 aagcaaaaat agcgtgtgag aagctattga aacaagtcag ccatgagata gaactcaggg
     4501 cgatggaaag taggacagtc tagaagacaa caaaaagcac ctgacggcaa tcaggcgcat
     4561 gacaaaatta ttcaagaaaa ttataacacg aaaggagcaa aaatggaagc agttgaaatt
     4621 gtaagaatta aagatgtgat tattgaaaaa gtctctgcta atgatgaaga gttaaaacgt
     4681 atctttggat gttcaaaacg acaagcagga gagcgaagaa gagaaatgca aaaactccct
     4741 agtcagcaaa aacatctttt ggatagtgga caacttgtaa cgattaaagg tttctatgaa
     4801 tacttgcaat atcgtggaac taaagcttgg aaaaaagaaa tggaaacaag caagaaaatg
     4861 aggtcagcag gatgaaccta ctatcaagaa tcaaaaacta tttttcggaa gaggtcaaag
     4921 aaactaatct cgactggaaa gaggtcgctt tagacctcaa tcaatcacta attgaaacac
     4981 aggaaaaact tcaagaagcg aatcaagaaa tcgcagactt gaagaaaatc gtagcaatct
     5041 acaaagaaaa ggagaaagaa aaatgatgga atacatttac ctggtaataa tcgtaggaat
     5101 tggactatgg tcgctagtaa ataaactaga tgaccacgct gaaatgaaac aaaaagagcg
     5161 ccagctgatg gcaaacaatg tcgcacggat gaatctgaga aattcagata agcaatttac
     5221 ttatgatgta gaaccgcctg aagggttgaa ataaggagga gaaacatgac tcaagcggaa
     5281 caaattaggg aatattatag agagcaccct gctgcctcat gtgatgaagt ggctgaggtt
     5341 gtcggtacaa caaaaagcaa cgtaagtgca aacctggcca aagacatcaa ggcaggcaga
     5401 tgcgttcgct tggaagataa gtcatacgac tactcgcctt actataacca tacacaggca
     5461 ctcactgagt tggttgattg gaagaatgat actagacgtg agtgggtgga tatgctgaca
     5521 agagcagcag aaaaagaaac ggttagcaat gttatgcgtt tgttaatcaa agaagcaaat
     5581 aaattgatga aagaggtgac gaagtagatg gttcgaaata aattgacaga tttaaccaat
     5641 actcttttcg cccagttgga aacattggac gatagggatc ttactgcaga tgaattaaag
     5701 acggaactcc aacgttcaaa acagatggtc gcaatctcag gtcaaatctt acaagcaggt
     5761 caattggcgc tagatgctga aaaattcaaa gacaaggtag gtgaagtcaa tgccccgatc
     5821 gctttgctgg aaggatgagt atacagagta catgcatgag atatgccctg gccgattaac
     5881 tcctgaagta accaggttac taaatgagaa atttggtacg acctatacca agactcaaat
     5941 aggagaagta cgcagacgtt tagggttacc tgttggaaaa gtctatcaag gtaaattgtt
     6001 gacaaaagaa caacatgatt accttgtgtc aatccaaaaa aataagattt ctcgcgatgt
     6061 cgcaaatgaa atgaacctaa aatttggatt atcactgact gagaaacaga ttaagagtta
     6121 tcgaagaaat aataatctac atagtggttt gacaggaaga ttcgagaaag gtcagactcc
     6181 tcacaataag gggaagaagt accccaatat gccaaaaaac agcgggcagt tcaaaaaagg
     6241 taatcgacct ctgaattatg tacctgtcgg tactatcaac tacacaacag acggttatcc
     6301 aaaagaaaag attggagaac ctaatcaatg ggttttgaaa caccgcaagg tttgggagga
     6361 acatcacggg ccaataccaa aagggcattc gattgtcttc ttggacggtg ataaaacaaa
     6421 ctatgatatt tcaaacctgg catgtttatc taaaaacgaa attgctagaa tgaatcaaaa
     6481 tcatttattt acgtccaacg ctgatttaac caaatcaggt attggactaa caaaactcac
     6541 aaacaaaatc agagaggtag aaaaaaatgg ctagtttata cgaactgaca ggtcagtttc
     6601 tgacagttta tcaaatggat attgatgacg aaacaaaaac ggacacactt gaggctatcg
     6661 attggcaaga acaattcgaa cagaaagcag aaggatatgc ccatgttatc aagaatctag
     6721 aagccgacgt ggccatgtac aaggctgagg aagagagctt caaagccaag aaacaggtgg
     6781 cacagaaaaa gctggattat gtaaaggata acattatggc agctatgaat gtcacggggc
     6841 aaaccgaagt taagagtggt gccctgatta taaaaattgc taagaatcca gaatcagtca
     6901 aggtcaacga agacgacctt ccgaaaaaat attttacaaa aaaagtgacg cttgcgccgg
     6961 acaaaaaaac actcaaagag ttgcttaaat ctggcaagaa agtcaaaggt gcggaacttg
     7021 tccggacaga aaagttggtg attaagtaat ggaattgatg aataaaacac gagtaacaga
     7081 ttcactagca gttgtgattg gaccagaatc gattgaagta cttgttactg aaggttttct
     7141 atttgatgtt gcgattcgtt ttgtaaaagt agacgaaaca aatcttgatc aaggaaatga
     7201 aaagccagta ttcactccgg aatacaagct ggtcacagtt gctaaataca aggaaaaacc
     7261 tatctttgaa tcggaggaag atattcgaaa atttgagaag caagcaaaag aagttaaatc
     7321 gctatttgcc tttgcaaagg taaataaaca aaattggttt aacactgccc tttatccagg
     7381 agtgctgact gagaaagttg gtgtttgatg aaaattttag ctattgatcc aagcagtaat
     7441 aaaattgaaa ccagcacaac aggagttgtc ttgttggata atgcaagatt agttgatagc
     7501 tgggttgtct cttatggtat gagaggtttc gctgattggt ttcacgaaat cggaacaaat
     7561 cttgaattcg atgtagttat tgttgaagaa tttaaggcga gggataacga caagtcgaaa
     7621 gataatagcg tggcagaaac catcgcctat atccaacttt gctatccagg tgccattctt
     7681 caattcaatg caggttacaa gtcggatatt ccaaacgatc ttttgaaaat cttagacctt
     7741 tggaaatttg aaaaaagtca tcatcaagat attcgagcag cagcaagact tggattattt
     7801 tgggcaatga gaaatgatat tgaagaagtg gttcatgata tcggaaaggt ggtgagtgag
     7861 tatcacaata acgctaagaa agtggcaagc tgaagcgatt aaaagaagtg aacatttatc
     7921 taatggaatc tttttagagg ctcttggggg cagaggtaaa acgatctgtg cacttgctat
     7981 tgcaaaacat aaaaaagcta aaaaaatcat catcacaaac aatcgactag ctattctgaa
     8041 tggttggata gatgcagtca agtttatgaa ttttgataaa gatgttgaga ttatcattca
     8101 gacagataga tatcttcaaa atcaagtcaa aaaggggcat aaattagatt gtgatgtgct
     8161 gatagtagac gaatggcaga atatgtcttc tgacaaacaa gtggccttat atcgcaaaat
     8221 aaagcgaaaa tacacgatag gtctttcagc gacaccaatc cggaaaaaag gacaaaattt
     8281 ctatccgctt gaaaaaacgg tatttggttg ggcaacccca aataataaat ttgactggca
     8341 aaagactcat gggaaaatgg tctatgatcc attcagctac tcaaaagaga agtgggaaga
     8401 tttcaggaat tatgaaagtt atatctcaaa cttgccgaac tttttccgct gggaagacat
     8461 tgaaaagatt gagaatgcag ttgagaataa cggttttgag attaagtttt accaaaagag
     8521 agtcgcctct ggcaatccag aaaaacttgc agaatttaga aaactaaatc ttgtaacagt
     8581 ggacggcaaa actgcaatgg ccaagcaatc gtttggaaga aagacctttg aacgctacct
     8641 taatcaaaca ggcgtagcag tcgattttcc aaaattaaag ccagtaaatg cagatacgcc
     8701 attgatgtta caacttgacg gtttaatcga acgagcacca cacgatatgt tgattgtcag
     8761 taaatctaag cagattgtca acgtcattag cgagcgccat cctgaaattg gaatctggac
     8821 gggcgatatt caagaaggac tttataagaa attcgtggtt gctactagtc aagtgttagg
     8881 tgtcggagta gacggcttgc aacacaaata ccaaactatt gtcgtattgg atccagtaga
     8941 agaaggttct ggagaatatg atgattatcg acaattgctc tggcgcataa caggaagtcg
     9001 tcagcagcat gatgtaaatg taattgaatt ttattataaa gaaagttaaa aaaaagagga
     9061 aaacagaatg aataaaacaa ctgaaatgat cgtatttcgt agccgtaaaa ctggagaatt
     9121 tcttaattct tacaaggaca gaagttcttt agcatttgca gctgactttt gcagcttgga
     9181 atattgtttg aagcttcctc gtaaaaaata cgaagacaac aaaaagactt acaaggctct
     9241 tgctgcagct tttgactgtg aaattgtcgc agttgaagcg gaatacaaat tgacctatcc
     9301 gaatggatca gaagttgaac ctatcaagcg tgaccgttca tcaattgagg acatgattaa
     9361 ggatattatt ggaggggttc tctaatggca tttacacttc cagcaaataa accacaagtt
     9421 cctaaagata ccccacgaaa ttttttcatc tacggtgaaa ccatgagcgg aaagtcttat
     9481 cttgcaaatg aattcccaaa tccaatcgtt ttgaacacag acgggaatgc agaagctaac
     9541 actgttccaa gcattcagct gatcaatgaa aaagatgaca agggacgaat taccaattca
     9601 gtaattaagc agcttggaga tatcttgctt gctctccaga cacagaagca ctcttatgaa
     9661 acagtcgtta ttgatgtaat tgacgatgtt attgaaatga ttaagattgc agtttgtgat
     9721 gaattaaccc cagttggtaa acctcgcttg aaatccttgt cggaaattcc atacggcaaa
     9781 ggatacgact tctttaacca agctatcaca gaattagtca ttgacctcaa agcattgcca
     9841 atgaatgtta tttacatcag ccgtcaggta tctgaatatg atgacaatgg caatgccacc
     9901 aaagacaagc caagcttgaa agataagtat gtcaatctta tcaatggaaa ctctgatttg
     9961 atgatccaca ctgaaaaact cggcaacaac tacaaccgtg aggttgaccg caagcgtaag
    10021 acctattatg cggaccaggt tgatgacaag gccatcttga aaatcttggc aactatccgt
    10081 ggggctgttg agcctgcaaa gggcaagcta gcccctaaaa aagaagcagc taagacaact
    10141 aaaccagcta agaccgaaaa aacaaaagag gcacctaaga aagaagttga ctctgatgat
    10201 gaactatttt aagaaataaa ggagaataca catgagctta ctagatatcg caaaatcaat
    10261 caaaaaagag ggctttgacc cacgcaaaga cagcgccaac ggtcctgcac caatcccagc
    10321 tggtacttat ccagtagtcc tgaagaaagc aaccttcaac gtatcggaca aaggctggga
    10381 aagccttggt tatcaatttg aaatccgtgg cggtgattac agtggacgct ctgaatttgc
    10441 aacatttggc acactgactg aatggaacgg taagaacctt gactgggcag ttgaacgcac
    10501 tatgaaattc tttatcaaag ccttggtcct tgctggcgac agtatgcaag gaaatgaaga
    10561 agacggtaaa gccttggaag aggctctaaa acgtaaggca gttggctctt actataacct
    10621 tgttatctct gtgactaagg ggaaagatgg ccgtgagttc cgaaactatg accttgaaga
    10681 agaagaagca caaccgctga ctgaagctga tattgatgac gatgacctcc ctttttaaga
    10741 aataacaagt tctgggtcat tgatgaaact gatgaggaat ttggtccttt cacgacagta
    10801 gaagaggctt atacagctat gctaacatac ttggatatga ctgaagccga atatcagtca
    10861 aactatacgg cccaggaact tgtttatatt tacaaagagg agaaaaaacc atgccgtcga
    10921 tgaaagaata cgcattacag taccaaaagt tagggttctc agtcattcca atcaatccta
    10981 aaaacaagat gcctttgatt gattttgctg ataagccagc catgactcca tctgagattg
    11041 aaaacttttg ggacggctac cctaatgcaa acattgccct aaagactacc aacttctttg
    11101 tcattgatat tgacaaacac ggcaaatcga acggttttga atcgctaaaa aaatggaaac
    11161 atctaaattt aatcgaaccg acactgcaag ctaagacggc tagtggcggt aaacatctat
    11221 tctacttcaa acgagaagat gagccgatca ctcagatgat tggattcttg cctggtgttg
    11281 atattaaggc tcacgaaaat aattatgtgt tagtcgcacc ctctgccaca gataaagggc
    11341 agtatgagtg ggatctggaa aagtctaagg aaggtggcac gatggtcact ccttcaaaag
    11401 atttaatcca gtctataaaa aaacagtatg gcgaaactca cggttataag tatgatggta
    11461 aggacggtct tagggattta gttagacgtt cacatactag agaccgaaca cagactacag
    11521 atctctttga aaccatcgcc cttggttttg gtgatgaagg tggacgaaat gacaaactag
    11581 caaaattcgt aggtggtctc ttatatcgtg cggtcgacga tggtgtagtt gttcaacttg
    11641 caagattagc aaatgcaaat agtccaaacc ctttgcctga aaaggaaatg atgcgtacta
    11701 ttgaaagtat gattaaaaaa gataggaggt gattgtgatt ggtaatgtag taagtattga
    11761 ctcacaacct aagatgataa cgactgccaa gggagacatc aaggccaaca gtccaagtaa
    11821 tgtgttgatg tctttcaaag ctgatgatca gttgagtatt tacctaaagc acaacgattt
    11881 ttcccaagag catgaactcc ttaaagatat caagatcggc aacactcttt ttaaaaaagg
    11941 tgagctccct tctaactttg attcagtcgt aaaagtttac tttgaaagtg tgttaggtgt
    12001 tgctttctca aaccaagcga tgcttgatgg catggagact ttcttttcag aaagatcata
    12061 caatccagtt attgagtata tggagagagc aactgaaaag tgggacggca gaaaccggat
    12121 tgaccgcatg cttcaagtat atctcggcgc tgaagatatc cctttagttt ctaaaatcgc
    12181 tcaaatgtgg ctagttggtg cagttgctaa agtttatgat ccatacgtta agtttgacta
    12241 tgttctggat ctggttggtg gacaaggagt tgggaaaacg tccctccttc aaaaattggg
    12301 tggcgaatgg tatacggatg ccgtaacaga tttctctaat aaagacaatt acgacattat
    12361 gttaaagagt ctaatcgtca acgacgacga aatggtggcc agtaatcgga tgagctttgc
    12421 agaaactaag gcctttattt ctaaaactag cctacgttat cgtaaaccat acatgaaacg
    12481 cacagaagag tttgccaaaa acttcatttt agctagaact actaaccaaa cagaatacct
    12541 caaggacaaa accggtgaac gtcgttttct accagttatg gcagatagta aacggcaaaa
    12601 aaaacatcca atggaaatcg agccagagac aattgaacaa atctggggcg aagccgttac
    12661 aatctatcgt gctggtgctg atttgatgtt tgatgaaaat acagaggatg aactgaatat
    12721 ctaccgtgaa cagttcatgt atcgtgatga agttgaatta caagtgcttg aatatcttga
    12781 tatgcccgtc cctgaaaatt ggcaaaactg gtctattcag caacaacatc aatacacaag
    12841 taaatatttc gataatagta gcgactttga tcctggaagc aaaaaactag ataaggtctc
    12901 aactcgtgaa atgatgtaca acttatttat gagaaattcg aatgacagga agctgtcaac
    12961 gaagattaac atgatcatgg ataatcatcc tgattggaaa aaaagtgttt tccgggcagg
    13021 aggtaaaagt acaaaagggt tcgtaagagt gaaagattcg gaaaaaacta atcggtagca
    13081 attaaaaaat tatcggtagt catcggtagc agttgagggg gtagatcggt agcattctac
    13141 cgataaaatg agacatcggt agcacatcgg tagcagtcta accccttgat attactgact
    13201 tttatttaat atttatatat aatgctactc ttctacctat atttttaaaa aaagtatata
    13261 aaataatagt aataatagag aaagcctata aaatagggat tctttaaaaa tattttttac
    13321 tttttagaat ttatcggtag tacggtagca gtttgaaaaa aagaggtaaa aatgtcatac
    13381 acagtaacac tatattttga caacatggta gacgaaactc acctttttaa gaaaaagggt
    13441 gatgctgcaa aatgcaaggc tcagctcgag agcaagtatc gaggtgatcg aatgtataaa
    13501 gtaaagatgg aggagatgga gtaatgagtt atgatttgga aatcttagcg aaaatagaga
    13561 gtggagatta tatttgtatt gctgaaccta gatatagttc tccgacctac aatcttggaa
    13621 aaatgtttag ggtggctatg gattgggatt tcgaccaagg cacaatttac aatgttgctg
    13681 atatttttga aaatattaaa cgtggcataa ctgaattgga aaggcaacct gaaaaatatg
    13741 tacaatatga acctgcaaat aaatggggaa cgatcaatga tgcgttatat gttttgagat
    13801 cgttaaggga ctgtatttta gaacaagata ttgatacgaa atatttatat gtgaggtggt
    13861 aaattgaaac gaccaaacag atacccgtac actaaaaatc aatgggttga agaaaccttt
    13921 gatcactata cttataaaaa cgatatttgc tatacaagtc acattttaga aaatagactt
    13981 actggagaaa ttaaggacaa ggagttgaag tgatggaaga gttaaagaaa aaagttaatg
    14041 cagtatacaa ctggacggta gaagacggga agccgcaacc tcccaagcaa gatttaccac
    14101 aagcggtgaa agaccgggcg gactattttt gggaaatggc agaagatggt atgacgttta
    14161 tgggagcgat ggaatgcatc tttgctgatg aaaagcctac agactatgat ttgggagcta
    14221 ctaagggttg gttgccaaaa tctaaggagt ttgatgattg gattggctat tcgccaagca
    14281 tggctcaggt agttattgca gtttatttga tttatggagg aaactaagat gaataagcag
    14341 gaattgatta aaaaattaga ggaacgaaga acaataactg ggaattttca aggttatgta
    14401 gtttggtgga aggatgtaaa agaaatcttt gaacaactag gcgaaccgca accagtcaaa
    14461 gtaccgcagt gtgtggcgga atatatagaa tttaaaaaga aaaacaattt tcatgtttac
    14521 ggtgcaatga gagtaattga agatcattat gataagaaag ttcctgattg gttttacgaa
    14581 aataacatcg aaaaattctg tcttgcttgg cttaacggct acgaggtcga aaaagagaag
    14641 cggtattttg ttaagattaa agggaatatt aaagaaaata tgttggttta tggagaattt
    14701 ttgaaaaggt atttctttac aaaaagcttt agtttagatg atgttatata ttcccacact
    14761 cgtaaagaac tagaagacgc aaacttcggc tgggtgtttg attgttcagg gattgagatt
    14821 gaggaggtgg agtgatgagc cttacgctaa atagcacaat tggagactta gttttggcaa
    14881 tcggagaaat tatcgttggt tctgatggta aaaccactac agcgatactg gagatacctg
    14941 atcaaagctt ttacttagag attgcgctta aattgaagga ggaggtcata aattgaaacg
    15001 attcatagct atctggattc tgctatctgc tggattgaat atctggcaga tggataggat
    15061 tcgagatttg gaagagaaga agccgatggt tatctacaag gctgataacg taggtgctga
    15121 gatatgagga ggatttggca tgataccgaa atttagagtg tggcattatg aattaggtag
    15181 actgatgtca gtcaaatgta tgttttttca ggatagcgag attgaagaat ttgagttaaa
    15241 cgatgcttta atgaatgatt acattacagc ttatcctgac gaaatcgaac tcatgcaatc
    15301 aacaggactc aaagacaaga acggcaagga ggtattcatc ggtgacatcg ttaaatgtac
    15361 aagaggatgt ctccatgaag tatatttaga aaaagaatac ggtggcacat tcataggcgg
    15421 aatgccttcc atatatctaa agggattgct aaatgggtat gcgtggactg aagacgagga
    15481 aatcatcgac aatgtctacg aaaaccctga acttttggag gtaactcatg aataaacgtc
    15541 aacgcaaaaa gaaaattttg aacggtctga acaaagaaga aagataccac aggacgcatt
    15601 gtcctgtctg cgatagcgaa gctggtctat tcgacagata ttttaatacg tacggtttct
    15661 gctctgaata ttgtggttat gaatactatg gaatttcaag attataaaat aaaggattga
    15721 ggttaaaatg acattatttg atgaagtgca gcaattaagc tcagaaagcc acgcaaaatg
    15781 gttcgagcga tattttgaga aatataacct agaacaaaaa ctaaaaactt ctgctcaaaa
    15841 aggttataca ggttatttaa tcaatgtttg gtcagttaga gacgaatatc tcaggaatcg
    15901 attaggagat gaaataacgt ttgaagcgtt aagagaatta ttaggagctg gctttactgt
    15961 caaatataag ctttatctat ctaaaaatat tttcactgga caagatttcg tttctaacaa
    16021 gaaaattcac attacttggt aaaacaaaaa agccaagaca ctctctgtct cagcaataat
    16081 ctcaataata ttattatatc acaaaggaga cagagagtga acaaggctaa agaactattg
    16141 aaagagttgc agaatctgga catggacatt caaagccgta tagatgaaat taacgagctt
    16201 gaggcaggtt tgctctcaag tcctaagtgg tcagatgtca aagttcaagg tggtcaagct
    16261 agaaaagttg atgatgtcta tactcagctt gtcgtgatga aagaggctat agaacaggat
    16321 actaaagagg ttatcaacag aaagctccaa ctaggtagga tgatcaatag gcttaaaaat
    16381 ccaaaacata gaactatttt gagaatgact tacatcaata agatgtacgt tgatgacatc
    16441 tgtgacagca tgaggggcat aagttctcct acttactatc gtttgaagaa acaggcagta
    16501 aaggagcttg atattattct ttcagaattg atagtaaatg atagtaactg tacaggcatg
    16561 aagtctaaaa tctgttaaaa tggtagtatc aagaattgaa aagagaggtc tcagaattgg
    16621 tagatggtta cctgtaatgt cagggggctg taatggcctt ggaggttcaa atcctcccct
    16681 ctcctttgag tgtttgtgtc ctagaatggg gtaggcagta ggcttagcat tcatatatca
    16741 ctcattaact taaaaatggt tgcggaagcg actggacctc gcatgattgc gtagctaatt
    16801 atattccgga taagttataa gctagagggt ttgattccct cagaggtttt aaagactaca
    16861 aaaaataaaa aagaagtcaa aatttaatac gcacgcaagg ttgtagtcgc cttgcaagaa
    16921 ggtcgcacat cgtgtggctt tttttgatta ttcgaagggt ggtgatggaa aattgagtgg
    16981 attgagaata aaacaaaaga gatttgcaga tgagtacatc atctcaggta atgcgacgga
    17041 agcctataag aaagcaggtt atcgtgtttc tagtgataga gtggcaggcg ttgaaggaca
    17101 taagttacta aagaatccta agattaaaag ttatatagat gaacggttga aacagcttga
    17161 ttctgaaaaa atcgcagacc agcaagaagt ccttagttat ctaacctcgg taatgcgagg
    17221 agagacgcaa gaacagactt tgataagcat cggagaattg ggtcaaacga ttacggatat
    17281 tgatgttgga gcaaaagaca gaatcaaggc agccgaacta ttaggaaaac gtcataggct
    17341 ttggacagac aaagtagagg cagacgtttc tggaacggtg gtgtttgcaa atgagtcaga
    17401 cataccagat taaacaaagt gatattgtaa tcgacctacc taagacagta ggagctgggt
    17461 acggacagtt ctggcgctca agaaatcttt atcgtgttgt aaaaggttcc cgtggttcga
    17521 agaagtccaa gacaaccgct ttgaattatg ttatccgtct tttgaagtat ccctggggca
    17581 acttgcttgt tattcgtaga tactcgaata ccaacaagca atcaacttat acggatttta
    17641 aatgggcgtg taatgtgttg ggtgtgactc atttgtttaa atttaacgag tctttgcctg
    17701 aaataactgt aaaagcgact ggtcaaaaaa tactgttccg tggtttggat gatgaactca
    17761 aaattacatc tattacagtc gatatcggta gtctgtgttg ggcatggttc gaggaagcat
    17821 atcaaattga gactgaagac aagttcagca cggttgttga gtctatccgt ggtagcttag
    17881 atgtacctga tttctttaaa caaatcacag tcacatttaa cccgtggaat gagaggcatt
    17941 ggctcaagcg tgtattcttc gatgaagaga cgagacgggc tgacacattc gctactacaa
    18001 ccacttataa atgcaatgag tggcttgatg aagtcgatat caaacgctat gaggatttgt
    18061 atcatacgaa ccccagacgt gctagaatcg tttgtgatgg cgaatgggga gttgctgagg
    18121 gtttaatcta tgaaaacgtg actgtcaagg atttcaataa agatgaatta ctacaagatt
    18181 cagctaataa attatgtatc ggtcttgact ttggttttac tcatgatcca actgctttgt
    18241 gttgttcgtt gataaatgat acgacgaaag agatttatgt ctttgatgag gcgtataaag
    18301 tcggattgat aaccaaagaa gttgcgaaga tgataaagga caaaggttat catcgctcac
    18361 aaatcattgc tgatagcgca gagtcacggc tgattgaaga gctcaggtca gaacatggca
    18421 tatctagaat aaaagagagt cggaaaggta aggatagtat tatggcaggc gtatccaaat
    18481 tgcaaggata cgctatttat gtgcatccag attgtaaaaa catcatggat gaattttata
    18541 gttactgcta ccagcgagat aaagaaggca actggttgaa taaaccagag gataaaaaca
    18601 accacttgat ggacgctttg cgttacagcc ttcaatgtat cgaaggtgga aaagcaaccg
    18661 tccgcagacg ttctgattat ggtctataga gaggaaagac atgtaccaat atttaaccta
    18721 tccacgggat ggatatgatg agggttcttt gaagaaagac ctgatttaca aattgataac
    18781 gatgcatagc actgaaggct cgcatttgaa gaagcttaaa agctactatt tgggtgagca
    18841 tgctatctta gaacacacga gacgcaacgt gaacgcaccg aattacaaga cggtagccaa
    18901 tcatgccaag gatatcgcag acacggctac gggctatttt atgggcaatc ctatcaagta
    18961 taacaatact gctgacggtg atatcgatga actacttaca gcctttgatg gtgctgagat
    19021 tgaccaagta gatgctcaga atgctttgaa catggctatc tatggtcgtg cttacgagta
    19081 catctatgct aaagagggta tggctgagtt ggattcaact agtattgatc cggagaatac
    19141 tttcatggtc tacgatgata gtattgagcg gaagcctttg tttgcggtct attactatga
    19201 agtaaaagac gatacgaaag acactaccaa gtaccaggct gaggtcttta ccgaaaatct
    19261 gcactatcac atggtgctga gaagtacaga ttcaggaaca actcagaatg agcaggtaac
    19321 ccctcacaac cttgggcaaa tcccaattat cgaatatcgc aacaatcact ttgcaattgg
    19381 tgactatgag caacaaatta gcttgataga cgcttataat tccttgatgg ggaatcgtgt
    19441 caatgataag gaacaggctg tagagtctat ccttgtcttg tatggcacgc agttagcaga
    19501 cactccagaa gacgctaagg tagcaatgaa gattctttct gaagaaggtc ttttggaatt
    19561 gccgggcgat agtgcaaggg ctgagttctt gaagaatacg ctggacgaaa gtgctactga
    19621 aatcttgcgt acagctctta aagaggacat ctacacattt agccatgtgc ctaatttgac
    19681 tgatgagaat ttcgcaggga atacatcagg cgtagccatg gaatttaagc tgatgggcct
    19741 tgagatgatt actaagacca aggaagcgaa ctataagcga ggattgcgtc agcgtattgc
    19801 gatttttgct cattacttag gtatgaagca gattgcttta gagtctcatt caatcgttcc
    19861 acaattcagt cgtggtttgc ctaagaactt gttagaaatc tctcagattg tgaacaattt
    19921 ggaaggtaaa gtgaccaata ggcagcttat ttctctcttg ccgtttgtgg aagaccctga
    19981 cgctgagctg gaagccttgg aagaagagaa aaagaagaac atggaagaca tgccgatgtt
    20041 caacaaagac aacacgaaac ccgaagacga ggtagaggat gaagaatcag gagtattggg
    20101 cgaagaggaa agccaatctg atttaccagc agatggacaa ggccgaaaag caggcagacc
    20161 agttcgataa ggtctatcag gaagccaaga cttacttgaa taaggaaatc aataagattt
    20221 ttgataagtt ccaacgtgat tatgatctaa gtcaggtaga agctagacaa gtcttgaaga
    20281 acatgaaaga caagaaagac ttgaatgaac ttcgtaaggt gcttgaagca agaccgaatg
    20341 acccgaacat ccaaagatta ctagctgact tagacagccc agcttattct ttccgcatga
    20401 agcgcctaga gcgtttgagc gacgatttag atcgtatgcg tgaatctatc tatcattcag
    20461 aaaagacagg ctcagacgcc ttttatagcg acctgatgaa ggatagttac tacaaggcta
    20521 cctttgacct gcagcagcag acaggactag catacggctt ttctgggctt cctgagagcg
    20581 agattaaaca tctacagtct ttcagttggg taggtgacgg aagtacctac tctacagaca
    20641 tctggaagaa tacggggaag cttacttcta gcataaaaga tgaactactt atgagcctca
    20701 tgacaggccg agatacacga gaaactgcac aagcaattgc tgagaggttc aatgtaggtc
    20761 agaacgatgc aagacgtttg gttcggacag aatcagcctt ttttcacaac caaatggaac
    20821 tactcagcta tgaggaagca gacatagaaa agtatatctt tgtggccgtc ttagataagc
    20881 gtacatcacg catttgtcag gagcatgaca atcaggtcta tgatagggac aaggctgtcc
    20941 ctggtgtcaa ttgtccgcct atgcaccctt ggtgtaggtc tactactgtc ggatacgatg
    21001 aggacgcaga ctacagcaag ttgaagcgca gagcaaggaa tccagagaca gggaagaccg
    21061 agctagtgcc tgccgatatg acttataaag agtggtatag caagtatgtt gcgaaagacg
    21121 gggaaaaggt gtataatcaa gatacaagag aagccaaggc gaaattttat agcgaacaac
    21181 tattgtccaa aatttcagga gttgagccaa aaattacaag tgatatgcaa cgtatcgcag
    21241 gagaaaacaa attggcaggt cttgaattta ggaagaaaac agttgagtca ttatcacgta
    21301 aaattattgc agatagccta gttgaaaata taagtttgtc aaaagccgtg agtaagatta
    21361 atgacgcctt aaggtacaca actattttcg attccgatac ttttacagaa gagtatttga
    21421 agatgaaaca gaagcttatc gcagaaggtt ataaaattgt aaaagtaaaa aacacttggc
    21481 cagtagatgg accatacaaa ggtgtgaata cagtcattga aaaagatggt atcaactttg
    21541 aaatgcagta tcatactcag gaaagtttcg acttaaaaaa tggttcatta catgaactct
    21601 atgagaagta tcgtgatacg aatacatctg atctagaacg catgaaatta tttaaggaaa
    21661 tgcttgattt aagcaatggg cttgagattc ctaaaaatat agagagggtg aagtgatatg
    21721 aaagatatta aatactaccg cacaacgacg aacaatgctc aagtacttcg tttgattgat
    21781 ggtgtcatgc aagtttttga cattgaaaaa aagtgggtta atagcatgga ttggtttaat
    21841 aaaatctttt ttaatgactt tacggatttt gaagaaattt cagaaaatga tgcatttact
    21901 tatattgaca ggatggtagc ggcatgattg atattgcctt ggctatcgct aaaaaagcac
    21961 atgcagggca ggtagataaa gcgggtgttg attacataca gcatcctctc tatgtggcca
    22021 gtcaagtcaa cactgaacaa gaaaaagctg tcgctctttt acatgatgtg attgaggata
    22081 gcgatataac tgctgccgat ttattcgcgt ctggcttgtc aaatgaagtt gttacagcgg
    22141 tacaaatttt gacaaagaaa aaaggtcaaa gttatcaaga atatcttggg aaagtaaaat
    22201 caaataattt agcaagagtt gtaaaacttg cagatttgaa acataactca gatttatcac
    22261 gtttgaaatc tgttaccaat acagactacg agcgtgttaa aaaatataaa aatgcaattt
    22321 attacttaag cacctagaga aatctaagtg cttttcttat gtttagaaag gagcgagaaa
    22381 tgaaatatcg taaaaagcca gtagtagttg aagccgtgca gtttttagat acagaagaat
    22441 ctatagatga gctatgcgat tttggattag atccagtacg gattgattac gcagacttaa
    22501 aaaatcctct tttaaaaatc gaaacgcttg aaggattgat ggttgcaaca gaaggtgact
    22561 acattatcaa aggtgtgcaa ggtgaatttt atccatgcaa gcctgatatt tttgcagaaa
    22621 catatgaaaa aacggaggaa taaaatgtta gaaaaagcaa aacaattggc atcgcaagaa
    22681 ttttcacgct tatcaggtcg tgaaatcaaa gcagaagact gctttgtagt ttggtttagc
    22741 aagaccctgc aaaactggaa agctcttgtt agtacgaacg caattacatc aagcgaacct
    22801 tgtggaaatt atgcagaaat cacgcataac ggagacaaga atgagactta tgtggatgtt
    22861 tacgccaaag tttcaaatcg tgccattaaa gattaggagg tgatccaaca tcttgacttg
    22921 caggaataga ctgctataaa ttactgtaaa ttgctataaa ccgtgtcata tttgatgcgg
    22981 ttttcctatg ccctaaccgt atggaatccc gtacggtttt tatattgtct aagcattgac
    23041 gacactaaaa gctatggaaa ttacagtcgg ggacgacttt aaaaatagga ggttcgcaat
    23101 gaacgaagaa acacaaacag tcgaaacggt tgaagaacaa aaggtacctg cagaacctgc
    23161 acaacaaccg caagacgaga agaagtacac ggacgcagac gtcgacgcta tcatcgataa
    23221 gaagtttgcc aagtggaaat cagagcaaga agccaaggaa aacgaagcta agaaacttgc
    23281 caagatgaac gctgatgaaa aacagaaata tcagttggat cagcgtgagc aagaactagc
    23341 tgaccgtgaa aaggctattg ctcgtaagga attgaccgca gaggctaaag caatgctaag
    23401 tgaacgtgac ttacctgttg agttagtaaa tgtagtcgat ttgacaaacg cagagacggt
    23461 atctgaatct attacctcta tccaaaaagc atgggaagag tcagttcaga agggagtctc
    23521 tgaacgtatg aaaggtagtg cacctatcaa aaatgcacaa acagtccagc aagaagtcac
    23581 ggaaaaatgg cgtaaagact tcttgtaata aaagaaaaga ggaaaaataa atggcatttg
    23641 aagaattaaa tacagcagaa tcacgcaaga aacatcttgg gattattgag gatgtacttg
    23701 cagtaaattc atattcaaca ccgcttgtaa catcaagcga tgcagtaacc ttgcaaggtc
    23761 gctcttttac agtagcaact ggtaacacaa cagagttgaa agactacaaa cgtaacaaag
    23821 acaatgaatt tgatcacgtt gaagttgaag aaaaggttta tacccttgat gaagaaaaat
    23881 actggggtcg tttcgtagat caattggacg aacgtgactc taatggtcaa gtgaatatca
    23941 attatgttat tgcccgtcag gctgcagaag tagtcgctcc atatcttgat gaactacgtt
    24001 ttggtgcagc acttggaaac gtaagtgaca atgttgccat gggtaaaaca gcaggagcga
    24061 acaacgctta taatgcggtt cttgatgtgt ctgagaaact tgatgagctt ggaattacaa
    24121 aagaacgctt gctcttcgtc actccaagtt tctacaaagc gatcaagtct gaaatcgttc
    24181 gtctaccaca tggtgacgca gataagaaag tccttggaaa aggatatgtt ggtgaattgg
    24241 atgattacac agtctataag gttccttcta aattcctgaa aggtgttaat gcccttgcta
    24301 ctgctccagg tgttgttaca tctccagtac aagtagataa tactaagtac aacgataaca
    24361 ttccagggcg atttggcgaa ttggtagagc aattgcttta cactggtgca tttgttcttg
    24421 aacacttcaa gaaatacatc atcacaattg cagattctaa gcctgctgct aaaaaatcag
    24481 ctcaaggcaa aacagtaaac cgtgctaaag cgtggaaaac tggaacaacc tacaaagaag
    24541 gtgacacagt tactcatgcc gataaagtct atgtagcggt taaggatatt tctaattcat
    24601 caaccgcacc agacacagat acaactaact ggaaagaaaa aactggtaag aaataggtcc
    24661 gagttatgaa atttaaaatc aaacaagatt tctatgattg ggaatcaaat gtgaaacgac
    24721 tggcaggaga ggaacttgag attactgagg agcgctatgt tgagctggct gacaatattg
    24781 ccagcaacgg tgttgctatc tcagatgttc ttgagaaaat cctccctgaa cctgagttct
    24841 tagaagagga ttgatatgtc tatagagttg ctgaagaaat taacaggcga agaagatact
    24901 cagcttctca tgttgctcca aacaagagct acaaatctta tcttgtcaga gactaatcgc
    24961 acatctttga cacctgcttt aagtcttttg atacctgagg ttgctatcga gctccacaac
    25021 cgctcaggag cggaaggaga gcgttctaga accgaaggtg gtatagaagt agtctacgga
    25081 gaaaaaggcc tgtctacggg tcttctacag cgaatacgca tgcacaggct agcaagggtg
    25141 gcaggccatg tttttgaagc agagtagact gaaaccttat ccaatgcgac ggtttgaaaa
    25201 gactgtcaca gaggaaggtg tcgtaaaaga aggatatgcc aaggaagctg agacagtccg
    25261 ccttgaattg tggccagcta gtagcaaact acaatctgaa ttgtatggcg agcgtgtcaa
    25321 tgatattttg aacgcaaatg ccaataagtc agctactatc aaagtgaaag atggtgtgtg
    25381 tatcgatagc cagacggaag tgactcacag ggttatttct aaaaaggtct acacacatca
    25441 tcaagttttg gagttagagc gtgtcagggc tactaggggc agataggctt atagctaaat
    25501 gtagacgatt ggctagtaaa aaaactggcg aggatatcgt cttacgtgcg gtacacaatg
    25561 ctactataaa ggttgtccaa gcagatgcaa gaagactcgc accagcgaga gatggagagc
    25621 ttataactag tatcaaaact agggcaaaaa tggacggaga taaggctata ggcgaggttt
    25681 acaccaacct aaaatacgct ccttacgttg agtttggaac gggaccaaaa ggacaagcta
    25741 gccattctgg tatctctcca gaggtcagcg taacttacaa gtctagtccg tggtatgtgc
    25801 atgaagatca aatcaatgta ggaccttacc actttcaaaa gattggggag ttctacaaga
    25861 tgtatggtca acctgcccaa ccttatcttt atccagcttt gagagacaat caagagcgtg
    25921 tgtctaagaa tatttcgaat tatgtccgta gaaagataag agaacaaata aaatgattaa
    25981 tatcaagcct gttatttata aagaattgca aaaggttgca gataatgtga ccgatactta
    26041 tcctagcgat tgggagactt tcccagtcgt tattttttta gaagaacaaa acaagccggg
    26101 tgattggttt gatgaccagg aacaaaaatc atctatccgc tataaggtgg atatctttga
    26161 tgataccagc actagtgagt tagctgttaa aatcaatcag atttttgagt ctttaggttt
    26221 gcgaagaact gactgccaag acgttccaga cccgtctcat ttgagacata aggtcatgcg
    26281 ttttgaaggt atcgtcgact tacactcaga gcttgttttt caatttagaa tggagaatta
    26341 aacatgttag caaatggaat tacgctatct tatggcgaat ctaaagaaac ttatactaaa
    26401 cttgttggat tgaaagaagt gccagagttt ggtattgaac tcgaaaaagt agaaaatact
    26461 actcttgaag ataaagttaa gaagtacgag tttggtattg gggacatagg agaacttgag
    26521 tacaagttct cttataataa ttcaagcgca actgctcctt atcgtgtatt gcgtaaggca
    26581 gcagacgaca agaagaaact ctacttcgag caagcatacc cagacggtac taaggtcaat
    26641 tttgaaggcc aagtatctgt taagcttggc ggtggcggtg tcaatgccgt tatcgagttc
    26701 atacttaaga ttgccttgca gtcagagttg gaatttacag acggtgttgg aggttaatta
    26761 aatggcgtta aaatacacaa cttggaaagt tactgacgaa aaagagttga agctacgttt
    26821 gacatctcat caagctgcaa ctgtggaaga aaaaatcggc atgaacttgt taaagatttt
    26881 catgcctgaa gctggcgaag agttcacttt accgcctttg aaagttatgc tgttgttagt
    26941 tcacggcgcc ttgcagcagt atgaacatgg gtattctttt gaggatgtct atgatttata
    27001 cgatgaatac gtggacaatg gtggagacca aacaacattc atgacagagg ttttaatgcc
    27061 actctttgaa gtatcgggtt ttactccacg aggaagcaag gacaagaaaa cttccaagaa
    27121 gaaaatgaca gtagtcgagt aattttaaca gtaacgcaga ttattgagag gctttatcct
    27181 atgtttttgg atatcggggg caagcctctt gatttttggg atttgacggt gcttgaaatc
    27241 agggaaatga tagaaagcta caaccgtgtc aaaatccaag agcgtaaaga aaagattatt
    27301 gactcataca gactttcgca gatgatatcc aaccacgttt ctttattgtt atccaaagat
    27361 gccaaggcct ttgagttctg ggaatatgcg cctgagttgt ttgtagaaga acaacaagca
    27421 gtagaacagg aacgacagag acaagcgctt ttgttgcata aggaacggat gcgtgatttt
    27481 gcagagagac acaatcgcaa aagaaaggag gaagtgaatg gcaactcttg atgaattgaa
    27541 ggtcatgatt gacgctgaga tagcgccttt caggaagaag atgaaagaag tcgagaatca
    27601 ggtcaaagga acatctgacc aagtgaagaa tgccactgcc aaagttcgtg aacagtcgaa
    27661 ctctatcggt agtgcgtttg gtaagctagc taagttcgct ggttttgcaa tccttggtaa
    27721 gaaattactt gatgttggga tgtattcaac gcagactgct cttgaagtgt cagcggctat
    27781 gaaccaaatc aagcgccaga tgggcgagag ttcgcaatct ttcttaaaat gggttaacga
    27841 taacgccaac gctatgaata tgggggtggg tgaggcgacc aactacggtg cagtctactc
    27901 aaacttattt tctggattta taaaagatac caacaagcta agcgcctata ccgctaagat
    27961 gctgcagacc tcggcagttg ttgcggaagg ctcagggcgc acgattacag acgttatgga
    28021 gcggattcgc tcaggtttgc tagggaacac cgaagcaatt gaggacctag gaatcaacgt
    28081 caatgtggct atgattgagt ctactgaagc ctttaagaag ttcgcaaacg gacagagctg
    28141 gcaacagttg gattaccaaa cccagcaaca aatccgcctt atggctattc tggaacaggc
    28201 tacagccaag tatgggaata ccttgtctaa ttctgtaaat ggtcgtatca gcctatttaa
    28261 gtcgctgatg aaggacgcag cattgaacct tggtaactct atgttaccga ttatcaatgc
    28321 cattatgcct gtcttgaact cttttgcgat ggtcttgaag aacgttactg ctaaactcgc
    28381 tgagtttatc gctttgatgt tcaacaagaa agcaacagtg aaagatggtg ttggtggagc
    28441 agttggagac atgggtaacg ccatgaaaga cgctgcaggc ggagcaggag accttgctga
    28501 tgcagtagac gacgctggag attcagcagg aggacttgct gacaatcttg gagactccgc
    28561 caaaaacgct aagaaagctg ctaaagagtt gctaggtctt ttgggatttg atgagattaa
    28621 catcttgcaa aaaccaaaag atgacgacgc aggcggttct ggaggcggtg gcaaaggtgg
    28681 taaaggaaag ggaggcggtg gcggaccttt caaagacatc ttgccagaag tcgagttgac
    28741 cgacatggac aacaaattca agagcatttt tgatggtctt ggagataagc tcaaagggtt
    28801 gtttgacctc ttcaagaaag gttttgatgc agcatttaga ccagaaggta taaaacgcat
    28861 taagactgcc ttagaccaaa tagctaagac aatgggagaa atcgtcactg acccaagggt
    28921 tgtgaatgcc tttaaccgaa tggctgagaa aattgcttat gctttagggc aagtgacagg
    28981 ctcaataacc actatcgggc taggtatcgg tgttttcctt gccgaaagta ttgcaaatgg
    29041 ccttggaagg caaaaagaac gcattatcag ggcgctagtc gctttgtttg ataatgttgg
    29101 taacctttcc gaggcagtag gaaacatagc tcaggacttt tctagtgctt tctacgacgt
    29161 cattacctca actggtgcgg ttcgtatcgg tagcgctatt gtgtcaactc tgttgagttt
    29221 gacatctacc attgttgaag ttggtagtaa attagcagga agtttgttta aaggttttga
    29281 aaaagtcgtt gtgacaagcg ctcctaaaat ttcatcagtc ttccaaagtt tattagatac
    29341 tgttgcgcct gtatttgaga gcattgaaag gtctgttaac aaatttggcg atggcttaag
    29401 tcgtgtttat gatgaacatg tagtccctgc tattaactct attgctaatg cttttaatgg
    29461 gctaattgac attattcaga ttctctggga gaattcctgg caaccttttg ctgagttttt
    29521 atcaggagta ttcggtgtta gtattgaagg aatttcagat ttattaggag gtggcctttt
    29581 agccactttg ggactattgg cggatgctat taagttagtg gcagatggtt tcaccgtttt
    29641 ttctgactgg tgtaaagaaa acaaagaacc tatcgtagct ttgataacaa cttggcaaac
    29701 gattaatttc ttatcatggg cagaacaagc tggaggactt gcaggagcat tcagcttgtt
    29761 aggtagtaag gtctctttga ttgttggagg gattaagaat ctaggtcttg ctattaaagc
    29821 attgacattt gataagttgg tcagttttgg tgaaacaatc tatttgaaca ccttatatgc
    29881 aaaagatttt gtggtcaatt caggtaaaac aattgcacag ctaggaaaaa ctgctttaga
    29941 acttggtaaa tcagctctag catggactgc tcatgcagcg aaaatgggat tagcaaccgc
    30001 ggcgaaattt gcacattctg ttgcaacagg agtcgctaca gctgcaacat gggcttttaa
    30061 tgcagcgtta gcagttttga caagtccaat aacatggatt attgcagcaa tcgcagcctt
    30121 aattgctatc ggtgttttgc tctatcaaaa ctgggacact gttgttgagt ttgctaaaac
    30181 tgcatggcaa ggactatgtg attttatcag tggtatttgt caagcgattg gcgaattttt
    30241 cagcggtcta tggacgaaac tacaagaaat ctttgagccg ataggtcaat ggtttggcga
    30301 gaaattccag caagcatggg acgccattgt aaacatattc tctggcatcg gagagtggtt
    30361 ctctggtgta ttccaaggtg catgggacgc tatcgttaat atcttcacac caatcggctc
    30421 atggttcgga caacgttggg cagatgtgac taatgcgtta tccagtgttt caaactggtt
    30481 tggtgagatg ttcactaatg cttacaacgc agtaaaagat gcttttagtt ctattggcga
    30541 cttctttaaa ggcgtttggg atactgttaa aagtatcttc gtaaatgctg gtcagatggt
    30601 cggagaggca gtaggtggag cgtttaagag tgcggtcaat gcggttcttg gaacgattga
    30661 aaatgtagtc aatggcttca tcggaatgat taatggagtt ttaggcgttg tcagaaactt
    30721 acctggtcta ggatgggttg gtagtgtaag tacagttagc ctccctcgtc ttgcccgtgg
    30781 tggtatcgtc gatagtccaa caatcgccat gattggtgaa gctggtaaag aggcggtcgt
    30841 accacttgaa aatacaggat ttatccaaac acttggacga gtagtcagca gtgcggtagt
    30901 aaatgccatg gctggtgtta gtccacaagg tggattctct ggcgacggcg acatcgttat
    30961 ccaaatcgca ggccatgagt tcggacgggt agccatccaa gaaataaaca aggaacatga
    31021 acgagcaggt caaaccttgc tcaagattta ggaggttaaa tggcacaatt gacaatcaat
    31081 ggggtggctg tgaagcctcc caaatatttt caagtcggta ttcaagatat cgatggagag
    31141 acagggcgta atgccaatgg cgacatgatg cgtgaccgta tcacgaccaa acgcaaacta
    31201 gactgtgaat ggggtatgat gactcaggga gaattaagtc agcttttaca tgctgtatca
    31261 tctgaatttt ttgaggtatc ttatccagac cccatggatg gccaagtcac aaagactttc
    31321 tatgtcggtg ataggacagc tcctagctat acctttactg agaagtttaa accttggtct
    31381 ggcgctaaat ttaatctggt agagaggtaa gaaaatggac gctttaacta gacgacaatt
    31441 tgacagagcc atgtttgcca aggaaaggac gctggctatt cgtgttggtg attatgcttc
    31501 acgggatatc aaagaggcta gttttgagta tggctacatt aagggcgata cttataagcc
    31561 tggtggaacc tgcgctggta gcggtaaaat tacctttacc agtatcatta ccacgttcaa
    31621 taagctggat accctgcacc ctgagattgg tctactggtt ggggatacct accagtgggt
    31681 caagatgggg gaatacttca tcaacgatat tgagattgac cgaaaccgaa acactaccac
    31741 acttgaactt atggatggta tgtttaagct caatcgtgag tatgtgacag atttgcattt
    31801 cccagctgaa gtacgagagg ttattcagga aatctgcctg aaaacaggca ttgagttagc
    31861 gaatgactat ttcggaatca gcgcgatgcg ttatcatatt gagcaagttc ctgagggcaa
    31921 gaaactttcc tttagggata tgctgagcgc tatgactcag atgattggga tgtcttgttt
    31981 cttcaacaga gaaggcaaga tggaaatccg tgatttgact gagtccaata tcacgatcaa
    32041 cgctgacagt tacttcttgc atggcttgac caagagtgag attgagtatc agatagctgg
    32101 tatcacttgt aagacggaca agaagtctct gacagtcggt atgaagacag gtcggtcttt
    32161 ggaactggac aatgtcttta tgactcagag cgctttaaat gacttgtatt acaaactgaa
    32221 aaacctaact tactatccgt ataatctcaa ctaccaagga catttgttac ttgaggttgg
    32281 gcagtgggta accattcaga ccaacaagaa agagactttt aaagttcctg tcttaagtca
    32341 gagctttatc tttaaaggtg gtctgagagg tcgtatcagt gcagatagta aggctggaaa
    32401 cgatacccag tattcgtacg agggaacgat taccaagcag ataaagcaac aagatggcat
    32461 tgaagcaaaa atccaagcgc agattgaagc agcagataaa gattttgacc aaaaggtcga
    32521 caaaatcaaa aaagacttta acgatcaagt agaattggcc aaagccagag ctgaagaagt
    32581 caagagagaa ctgtctgaca ctatcaatca gcgatttaat agctttgaca acgggccatt
    32641 gaaagaaact aagcacaagg ctgaggaagc tttgcgaaat gctggcgcaa gtaccctgct
    32701 tgcacaggaa gctaagcgga ttg
//
LOCUS       DAVHBD010000026        29660 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000026 DAVHBD010000000
VERSION     DAVHBD010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.026"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(796..2523)
                     /gene="ezrA"
                     /locus_tag="VVK04_001250"
     CDS             complement(796..2523)
                     /gene="ezrA"
                     /locus_tag="VVK04_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU3989907.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2605..4551)
                     /gene="gyrB"
                     /locus_tag="VVK04_001251"
     CDS             complement(2605..4551)
                     /gene="gyrB"
                     /locus_tag="VVK04_001251"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU3989908.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGYTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVIKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4566..5129)
                     /locus_tag="VVK04_001252"
     CDS             complement(4566..5129)
                     /locus_tag="VVK04_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU3989909.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5214..5768)
                     /locus_tag="VVK04_001253"
     CDS             complement(5214..5768)
                     /locus_tag="VVK04_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU3989910.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5779..7002)
                     /locus_tag="VVK04_001254"
     CDS             complement(5779..7002)
                     /locus_tag="VVK04_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU3989911.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7039..9489)
                     /locus_tag="VVK04_001255"
     CDS             complement(7039..9489)
                     /locus_tag="VVK04_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU3989912.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLRKKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTEASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9689..10618)
                     /locus_tag="VVK04_001256"
     CDS             complement(9689..10618)
                     /locus_tag="VVK04_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU3989913.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     AQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10758..11045
                     /locus_tag="VVK04_001257"
     CDS             10758..11045
                     /locus_tag="VVK04_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU3989914.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11079..12413)
                     /gene="ciaH"
                     /locus_tag="VVK04_001258"
     CDS             complement(11079..12413)
                     /gene="ciaH"
                     /locus_tag="VVK04_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU3989915.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12403..13077)
                     /gene="ciaR"
                     /locus_tag="VVK04_001259"
     CDS             complement(12403..13077)
                     /gene="ciaR"
                     /locus_tag="VVK04_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU3989916.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13186..15732)
                     /locus_tag="VVK04_001260"
     CDS             complement(13186..15732)
                     /locus_tag="VVK04_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU3989917.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIAVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGADAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15855..16295)
                     /locus_tag="VVK04_001261"
     CDS             complement(15855..16295)
                     /locus_tag="VVK04_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU3989918.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(16270..17139)
                     /locus_tag="VVK04_001262"
     CDS             complement(16270..17139)
                     /locus_tag="VVK04_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU3989919.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17181..17909)
                     /locus_tag="VVK04_001263"
     CDS             complement(17181..17909)
                     /locus_tag="VVK04_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3989920.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17917..18396)
                     /locus_tag="VVK04_001264"
     CDS             complement(17917..18396)
                     /locus_tag="VVK04_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU3989921.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(18407..19105)
                     /locus_tag="VVK04_001265"
     CDS             complement(18407..19105)
                     /locus_tag="VVK04_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU3989922.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLKPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVVSETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(19098..19364)
                     /locus_tag="VVK04_001266"
     CDS             complement(19098..19364)
                     /locus_tag="VVK04_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU3989923.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19432..20358)
                     /locus_tag="VVK04_001267"
     CDS             complement(19432..20358)
                     /locus_tag="VVK04_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU3989924.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELAETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20433..21248)
                     /locus_tag="VVK04_001268"
     CDS             complement(20433..21248)
                     /locus_tag="VVK04_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989925.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21252..21572)
                     /locus_tag="VVK04_001269"
     CDS             complement(21252..21572)
                     /locus_tag="VVK04_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU3989926.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21779..21859)
                     /locus_tag="VVK04_001270"
                     /pseudo
     CDS             complement(21779..21859)
                     /locus_tag="VVK04_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21903..23900)
                     /gene="metG"
                     /locus_tag="VVK04_001271"
     CDS             complement(21903..23900)
                     /gene="metG"
                     /locus_tag="VVK04_001271"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU3989927.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(24024..25283)
                     /locus_tag="VVK04_001272"
     CDS             complement(24024..25283)
                     /locus_tag="VVK04_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989928.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25285..25986)
                     /locus_tag="VVK04_001273"
     CDS             complement(25285..25986)
                     /locus_tag="VVK04_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3989929.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25970..27169)
                     /locus_tag="VVK04_001274"
     CDS             complement(25970..27169)
                     /locus_tag="VVK04_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU3989930.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27434..28780
                     /gene="gor"
                     /locus_tag="VVK04_001275"
     CDS             27434..28780
                     /gene="gor"
                     /locus_tag="VVK04_001275"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU3989931.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TTGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28977..29513
                     /locus_tag="VVK04_001276"
     CDS             28977..29513
                     /locus_tag="VVK04_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU3989932.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
BASE COUNT         8833 a         6484 c         5292 g         9051 t
ORIGIN      
        1 ttgtttgatt acagtctaaa agttctataa tctctttata agatttgccc atcagacgaa
       61 atataataaa ttgaaactag aatagtacac ctctacttct aaaacattgt tagaaatcaa
      121 tttgactgtc ctaatcgatt tgtactgttc ttatttcaat tttactatag aacgatttga
      181 aggtgtttat gatatttagc tgtacgagag tcttttaaaa gtgttttgat ggtttggatt
      241 tcttctttag ttgatttcat attactatta tatagtgctt ttttatttta gtctggtata
      301 aatagcgaga aatatctatc ctatcttcta gaatgtcttc caaacgagaa aactctcgta
      361 aacaaagagg ttttagaggc ctatttaccg tagactaaag ttgtacaaga aaagtgcaaa
      421 taagaaatct ccagattagg aactatccgt gagttctcta gtctggagat ttttcaatag
      481 acttcattat tggacggtta ccaagttact caaagtacag atttgaagct gcagataaga
      541 ctgacgaaat cactttaata ctaaatgaaa atcaaaaagc aaactaagaa gctagcctca
      601 ggctgtactt gagtacggta aggcgacgct gacgtgattt gaagagattt tcgaagagta
      661 taaaacactg ttttgaggtg gtggataaat cggctgggca aaaactcaat ctcaggagaa
      721 aatgaagtaa atctccccac aactatagaa aaagatttga ttctgctcct cacacaataa
      781 aatctttttc ttttattaaa aacgaatcgt ttcacgtgtt ttctcatatg aggtaacaaa
      841 gcgattggtt acaccaggct ctgccacttc caatgcttga gaaatcttgt caaatgaagc
      901 gtgataatca aattcttttt caaaaatatc taaagcttcg ttaaatgctt cttgaatgcg
      961 ttcatcaaat gagcgatagc ggttagaata ttgcaagagt tgctctgtca aagttgcata
     1021 ttgtacaata ttataagttt ccgtttctaa agcttccata tcattcgttg caatttcaag
     1081 aactcgggta acagattcaa tgttaatcat tttttgttct aactcaacca ttaaatcctc
     1141 ggtattattg cttgccgtaa agaataactt caagaaagtt tgtggaatac ctggcagatt
     1201 gcgtttttcc atgtatcgct tgatagtatg gagacgattg acataaacat tggccttttg
     1261 acgtgcatta atatcatctt tctcaatttg tgtcaggcgc tcactaactg aaatttgctc
     1321 atcttcaata tcttttagtt gagtttgtaa atcctcaaga ttttcttcaa gaactgaata
     1381 agcttgggtt ggttcttctt gatttgaagt tacctcaaca atagctgcct caaaactctc
     1441 taattctgtc tgaatacgac gaacatggct tgcagctgtc tcaggaagta aataggtctt
     1501 gttcaaacgt gcaatatctt ctcccaataa agtattattc tctttcatat gttgaaggta
     1561 agttggaaga gttgcaagta gattttccac tactttctga gcagcaattt ctcgagtaaa
     1621 aatatcatac aaggcattga tttcctcttg tgcctgtcca ttctcatatt cggcattatc
     1681 caattccaac tgacgaatat tctcttggtt tttcttgaat gcttcataaa gcaagtggaa
     1741 acgcgcttca atatccgttt caacaaaatg ataattagca tcaattagtt tacgataacc
     1801 ggattccaaa tcctgtaatt gatctggcaa ttctgtagaa agcgtcgtaa ccaaggctgg
     1861 aacacgatcc acaatatgac ttaaggccaa aatgtgattt tctgtattat ccaaaatcac
     1921 tgcagcttcc acagggtcac ccgatgaatt caaggttaca aattgtgaaa attcagattg
     1981 gatattttct aattgttttt caatttcatc caaggcttga ccatactgtt ctgaattttc
     2041 agcaactcta tgctgaagtt cctcaaataa atccaaagca tgaagaacac gaccactatt
     2101 tttagattct tgcttctcta agtctgccaa agcattgcga attgccgcaa tatcttcttc
     2161 aatcaaagta atttgactct caatttggtc aatttgatga ctggccttga gaaaacgaaa
     2221 tgaatggtta taaccttctg cttcaaagag attattttca atatcggcaa aagagttgag
     2281 agataaatcg acccattttt gattccattc acggaaagcc acttgacttt gtccaatcaa
     2341 gtgcatattt tttacagctt ctacttcatc atttactgga agattgtata gttcttcttt
     2401 tctttcttct agcgcctcta atctcccctc gtttcgctta cgtagaaaga ttgccactac
     2461 ataagccaga actaaaatga ctgcaattgc aaccattaaa taaattagtt gtccattaga
     2521 catatcaaac tcctttttta cttgaaacaa tcgtaacgat tatatcatat tttttagacc
     2581 aagggaacta cttctcccta ttttttagac atcaagtgta ctatagacag cattttcttc
     2641 gataaactca cgacgaggct ctactcgatc ccccatcaac atatcaaaga ttttatctgc
     2701 ttctgcagca tcatctacag aaactctagc catcaagcga tgttcgggat ccatggttgt
     2761 ttcccacagc tgatgatcgt ccatttcacc tagcccctta taacgctgaa tagtcggttt
     2821 ggtacgacct tcactataac gggctaaagc ttcttggagt ttgatttctt gatctgcacc
     2881 cggctggata tattctttaa tctcgcttcc aaccttgaca ccatagattg gtggttgggc
     2941 aatataaaca taaccagctt ctaggattgg tttcatataa cgataaatca aggttaaaag
     3001 aagggtacga atgtgggctc catcgacatc ggcatcggtc atcaaaacga gtttttggta
     3061 acgggctttc gaaacatcaa attctgcgcc aaatcctgtt cccatggctg tgaaaagact
     3121 acgaatttct tcgttggcta gaatcttatc catacttgct ttttcaacat tcaaaatctt
     3181 accgcgaatt ggaaggatag cctgaaactc acggttacga ccagatttgg ctgatccacc
     3241 agctgagtct ccttcgacga tgaagagttc tgtttcagca gggttattag aagaacagtc
     3301 tgctagtttc cctggaaggt tggaaatttc caaaccagat tttttacgtg tgacttcacg
     3361 cgcacgcttg gcagccacac gagccttggc agccaaaatt cctttttcta cgatacgttt
     3421 ggcaatctgt ggattttcca tgaggaaatc ggagaaggct tcactgaaga ggcgattggt
     3481 aatcttgatc acttcgctat ttcccaattt ggtcttggtt tgtccttcaa actgtggatt
     3541 tgggtgttta actgagataa ctgcagttaa gccttcgcga acatcttccc ctgttaaatt
     3601 atcttcattg tctttcagta acttattctt acgagcataa tcattgataa cacgagtcag
     3661 tgccgtacgg aaaccttgtt catgcgttcc accttcatgg gtatgaatat tattggcgaa
     3721 actcatgaca ttttcatggt aacctgttgt gtactgcatg gctacctcaa ctgtgatatc
     3781 atccatctca ccgtctgtat agattggtgt atcaaagatt acatccttgt tctcgttgat
     3841 atattcaacg taactagcaa tcccaccttc ataatgataa tgcttggttt gttccaaacc
     3901 ttggcgctta tctgtaattg aaatttgaag accgcgattt agaaaggcca actcttgaat
     3961 ccgtttattt aatttatcaa aatcaaagat tgttgtttca gtgaaaattt ctgggtccgg
     4021 tgtgaagtga accgttgttc cagttctatc tgtataccca accacctcaa ggtctgcaac
     4081 aacatgacca cgacgatatt cttggtaatg aatcttaccg tttttatgga catgaacgtc
     4141 taattgagtg gaaagggcat taactactga cgaccccacc ccgtgaagac cacctgaaac
     4201 cttgtatcca ccaccgccga actttcctcc agcatgaagg actgtaaaga cggtctcaac
     4261 agcaggacgg cctgtttttt cctgaatatc gactgggata ccacgcccat catccacaac
     4321 agtaatcgaa tcatctggct caataaaaac ttgaatatgg ctggcaaatc ctgccaaggc
     4381 ctcgtcaatt gagttatcaa caatttccca gactagatgg tgaagacctt cttttgaggt
     4441 tgatccaatg tacatccctg gacgcatacg aacagcctct aagccctcta aaacttgaat
     4501 ttgactggca tcataatcct gtgcctgcag atttttgatt tcttctgtca tcttattcct
     4561 ttttcttata tgtctaatac ttgtcttaaa ttcacgatac tggtaaacaa gtgggtatca
     4621 agtcctgcag cttgacctgc ttcgatatca atcggccgat caccaatgac aagaccagag
     4681 ctaatctgat acttttctct taaataaagc atggattcgg gatttggctt tctcttaaag
     4741 cctgagctag aagtcaccac ttctgtaaaa taagctgcta tagaggtttt ttctaaaatt
     4801 tccaaaacct gatcatttcg atgagagacc aaaaaatgac ggccaccttg atttaaaatg
     4861 tcttccaata ggtcagaaac tccttcaaat aaaatcgggt gttcaagctc tctggcttca
     4921 ttttccttgt acttttctaa aaaattctct aaattgggag cgaatgtctc aatcgcaaaa
     4981 ggagtagaaa cctttaaagc ttgatagaca ctgtcatggt cttgtgtgat accatacagt
     5041 gccaatgttt caacaaatgc agctgttgaa gtttcataat tatccagtaa agttccacct
     5101 aaatcccaga tgtaatcgtg atatttcata cccttcatta tagcattttt ttatgaaaaa
     5161 agcgatgatt tccctgagtt ttccacataa aaaacgagag aataactccc gttttactga
     5221 tttttaccaa agacatctcg atagagcatt cctgttcgta aactctctgc gtcccctcct
     5281 agttgctcca ccaactcgta ggcaaaggca agggctgttg aaggaccccg actggttgtc
     5341 aactgaccat ctaccactac tgtttccttg acgtagtgac catcaaggat ttgctcttga
     5401 acgccgtcat aacaagtgta tcgcttattt ttcaatatct ctgcttgatt gagggcaatt
     5461 ggtgccgcac aaatggctgc tagtttcttc ccttcttgct cgaagctttg caattcttga
     5521 atcaaggtct gattatcacg taaatgtgca gaaccaggca tacctccagg aagaacaatc
     5581 atatcatagt ctgataaatc tccatcaaag acatgatctg ctcttacttg gattgcatgc
     5641 gaacccgtta cttgctcttc aaaaccaacc atatcacatg tgatattggc tcgacgcaag
     5701 acatctacaa ctgtcaaggc ttcaatttct tcaaagccct gagctaacat aactgctact
     5761 tttaccatga ttttctcctt atttaatttg ttttaataca acctttttcc gtttgaatgg
     5821 gacttttccg ctcttttctt cagctagatt agtctggtaa ctcatcgata aaagcaaacc
     5881 aacaccaatc agattactga taatagctga tcccccttgc gaaatgaaag gcaagggaat
     5941 ccccgtcaaa ggaagtagtc cagtcacagc accgatattc tcaaagatgt ggaagagcaa
     6001 catcataatc aaacctgtgg aaatataagt gtagaactgg ttatttgatt taagagtaat
     6061 cttcaacata cggtaaatca acatgagata gagggcaata accaggacag agccaataaa
     6121 gccaaaatct tctgcaataa ccgtaaaaat catatctgac tctcgaactg ggataagcag
     6181 attcgaagca ttaaatccct gaccaaataa gccaccactc ccaatggcaa tctgcccttg
     6241 agcctgctgg taagtcgttg tttgggcaaa ctcaaaggga ttgagccaag ccaaaatccg
     6301 attaatttgg taggtcggca ttccaatctg gtgaagaaaa gctcgtccgt ccttgctaat
     6361 aaagatagct aagaaaccag caactcctgt tacagcagtc acaaatactg ggataataat
     6421 tttccaagaa acccctgata ataaaacgat tcctgagaaa atggctacaa aaaccaaagc
     6481 cgtccccaag tcactttgaa gtgctaaaag aactaggact ggaatggtaa agagaatcat
     6541 ccagaaaatt aacaaaaagt ccagcggaac cgtgcgtctc cattccttat gtttctttgt
     6601 aaattggaca atgacacgag ccaacatgag gatataggat atcttcataa attctgacgg
     6661 ttgaaatagg gtaattccat ttattgatac ccagtttttg gcacccgttg atgcaactaa
     6721 gcttggatta taaaatacaa tcggcaagat cataagtccc aagcctaaaa tatatagaaa
     6781 gggggtcacc ttccaaagaa attctgtatt aaagagcatg accacaaaac caatcacaag
     6841 ccccaaggca atccaggcga cctgctgccc taaaatgggc agaatattat tgggataatc
     6901 atgactaacg gctatataga tagccaccac accgatgacc agtagaaaaa atactggcaa
     6961 gagcaaactg taatcgactc ttgagtcgag agaacgtttc atatatacta accttatact
     7021 ttcatacaat actatttatc aaagttcatt aaaaaatcta tcaatagcct cgtcaacttc
     7081 ggatcgagag atggttttaa cagtcgcttc ttctgctaga gatgctacta tttgtttgcc
     7141 gtatcgtttt ccgacgattc tcctatccaa aataagagtt aaggaacgtt ggtattcacg
     7201 tctcatactt cttcccaaag cctgttttaa acgaataatg gccattggca attgataatc
     7261 ataaaaggca tttttccctt cttgattcag ttcttgatta atctttttcg tcaagggttc
     7321 ttgaggattt tggaaaggaa gcctcggtac aacttgaatc acagaaggat ggcttgaaaa
     7381 atcaactccc tcccagaaac ttgctgcacc aagcaagatt tgttgttcac ctttttcaaa
     7441 gcgtttcttt agctgatgaa catccccatt tttatactgg gccaagtggc taactgtaag
     7501 taaatccgat actgctagaa gcatgtcttt agcggtaaag agaaccaaaa tcggttgctg
     7561 gaaagcttga atttccacta gtaaagcagc tacctctctg gcatagactt ctaaggaggt
     7621 ttctgttacc agagggaaat ctttgaccat gaccacttct tgttcctgtt ttccccgaga
     7681 ttcaatcttg acaaatttag cttcaggata gcctaaaagg tctgccaaag aaaccctctg
     7741 actaatctca agagtagccg atactcccaa gacttggcaa ctctcaggaa gtaaagagga
     7801 cagaagagta cggcctgatt ttgtagaaga aatctgaatt ttcttttgac tcgtttcagt
     7861 tacttcaagc cagtaatcac cttcagctgt aaaatagcga accagctcat caaagtcttc
     7921 tacttccaat tctgaaaaat actgatggag attgtccaga gaatctaaga tatttttcct
     7981 agatttgcca gactgaaatt gttctatcaa gtagagacac tcaaagcgaa tactttctag
     8041 tatccgttgt tgaaccctgt tttcttctcc tactaaagcc ttatcaatta aatcgataat
     8101 agattgtata tcgtaggtct cttgaagcag attttctaga gctaacaaaa tcttttggac
     8161 ttcatcaata atcagtaaac ggtcactgac aaattcagga ttatcttcaa gtctggttac
     8221 gagataggca tgattagtca ctaaaagctt gcaagtctct gccctttctt gactacgttt
     8281 ccaaaaatct tccgtcacaa ataagctctg ggatgataaa tttccatcat gacgaaggtc
     8341 tgctagaaaa tgttggtaac ggtagagttg cccgatttca tccaaatctc ctgtctctgt
     8401 ctcagtaagc cagaccaaga cttgcatttt aaagcgtcta aataagcgat tttcatcatt
     8461 ttcctgcaag gaatgataaa aggcatccaa cttcagataa ttttgtggtc cctttaagct
     8521 atgaatatct gtatggaaca cttccttgag gcgtttacct tcttcttcca tgatttgatt
     8581 ttgaagaatc tttgtcggaa cactaagaac aatttgtcgc tctttggatt gagataaagc
     8641 gggtaagaga tagccatagg ttttcccaat ccctgtcggc gcttgaatca gagagacagg
     8701 ttcatctttc aatagcaagc caacctcttt agcaaaactt tcttgttcct ccctcacttc
     8761 aaggttcaac agagaaatat ttttagaaaa gtcttgagat agttttcgtg gctccagaga
     8821 agcttccgtt ttcttaaaat atagaccttg aacttggacc aagtctggag aactcaggat
     8881 agattggttg cgataagttt cctcaataac caggtaggac tcatatagga gagcgtcagc
     8941 catttccagc aagcgttcca agagaccttt aggaagctgg gtcatctttt tccgtaaaaa
     9001 aagaagtaat tctgctgtag cttgggcatc tgaaagggct gtgtgtgcgt gtttaagagg
     9061 aattcctaat tctcgacaca aaatcggcaa gctatatttt tccagttcag ggaaaaagac
     9121 ctgggccaat tcgaccgtat caacacgagg gtttcttagc tcatagcctt caaaaaataa
     9181 attttccgcc aagagattag catcaaactg aacattatgg gctacaaaaa tcccatcctc
     9241 caccaagtca aatatttttc tggcaacttg cgaaaaatca ggtgcttgcg ccagacgttg
     9301 gtctgtcaat cctgtcagtt ctttgatatg agcatccaag ggttcatgtg gattgacatc
     9361 cgtcgtatag tgatcgacga tttctccgtc ctcaatcacg acaattccca cttggataat
     9421 tttagcctta ctacctgtgc tagttgcctc taaatccacc acaacatagc gattaccaat
     9481 cgttttcatt ataaaaaatt ataccaaaaa aagggccatt tggcacctgc aaacatagga
     9541 taattttcaa actcaagaac actacttttc ttaaaaatcc catcgaatag agcattctag
     9601 cctgctgatt tttgtaaaat agtgaagaaa tacgaaaaat tgagagaaga aatgtttgca
     9661 tcttccttct ctcaacgaat catgtatttt atctaaccat gtcaggatcg tagtcataaa
     9721 atcctgtatc aaggaaacgg tttttagggt gaagtttacg aacttcttca tccagcaaga
     9781 aggcttgagc atgactaaag ttgccctctt gaatcaagct acgcgcttgg ataaagagtt
     9841 ttgcaatctc aacaaagttc tgaccaggag tgtagagccc ttctagtttc cagcgagtaa
     9901 agccatgctc caccaattct gttaatttga tcatcaaatc aaggtcattg ttggcaaaga
     9961 tatgggtccc atgattatct tcaaaaatgg aatagtggct ctctggatca cttggctcag
    10021 ccaagaagag gtcacgttta tgcgtctttt catcatcgat atgtgtaaag ttatagtagt
    10081 tttgcaagag tggacgttta gaatgatgga tgacgctagc accgtaaacc aaaacttcag
    10141 caggaatttc caaaatctct ggcattttga aaagttcagc tgatggaatt tcacgcgcca
    10201 aaacagcctc agatgcgcca gccttttgtc cccagaagtt aatctgacga ctgctagtta
    10261 ccatggttga agcatcgtag atggtcttaa atgaataacc atcgcggtta actacgtaaa
    10321 agacgcctgc atccccaatc gtaatatagt ctgtcttgat ttcttccaag aagtctaaga
    10381 aaggcttgat acggtccatc atatcttggt gcatgagagc attgaccgca acgatcaatt
    10441 ccttaccagc atcatgaacc aacttagcga tttcacgtaa ttggtcataa ctaaaggtcg
    10501 ttggcagacg aaggccaaaa tctttctcac cgacatagat acggtctacg ccagcttcga
    10561 gtagttgttc aacttgttca atactttcag cagttgctgt aatgacaatc ttttccataa
    10621 gaaaaattat accacatttc tccaaaatca gccatgcttt gaaaatgaaa agggacttta
    10681 ttctttttgt aacctttctg taataattct ctgccgaaaa aatgataaaa taggtatgta
    10741 ctgttaagga gagaatcatg cccgtaagaa aattacaatc ctatgaggta gactatcaag
    10801 aagaattaaa ccagcagctt cctcattacc aagcttatac acctgaagcg caatctgatg
    10861 ccaatctcaa ggaaatccta ttttttatta atatcgctgt tttttgtatc tgtattgcta
    10921 tctttagttt tatcttttta gcattaaaat tatcaactgc tcttgccttt gccgcagcaa
    10981 tcggattcag cttacttgtt ttaaaagttc aacggtctat tatcaaacga aaacgtagaa
    11041 gataaatcca aaatatcgcc ccagttggag cgatattttt attttttctt tttagatggt
    11101 gtctgaatgg caatcttcac ttcaaagatt gttcccttgg gtttattatc tttgacagta
    11161 acagttcctt ttagagcatc tacaatttgc ttggctaggg ataatcctaa accaaaacca
    11221 cctttttgcc gggttctagc cttgtctact cgataaaaac ggtcaaaaat tttcttttta
    11281 tcttctgtcg aaataccgat tccattatca gaaacaagta aataaagatt gcgatcggtc
    11341 gccgagataa gaaaatcaat ttcaccatcc tcctcagtat acttgacggc attatcgaaa
    11401 agaatggtca tcagttgttt cagaagaagc tgatctgtga caattgttcg atggatacga
    11461 ttttcaaaac ggaagacacg attattttcc gaagcaatca tctcatagtt tgtgaaagtt
    11521 gtattaaaaa agctagttgg aacttctgca agctccggct taatcccatc atctctccga
    11581 gctaagttca gcaagcttgt cgttaaaaaa cgcatatttc ggacttcttc caaactcgat
    11641 gcaatgcttt cgctcacatc cataatggta gcttctggct tacgaaaaag ggtctctaag
    11701 cgattttgca aaactgcgag tggagttcgt aactcatgac tggcattttc cacaaaagac
    11761 tgttgcttct gcatactctc aagcaggggc ctaacactga ccctagctag atagagactg
    11821 gcaagtaaag acaaaatcca gaaactagcc atcacgacca caatcaattg ctcatgcttt
    11881 tgactagcct gctccaactg actggtatta atcaagacag cagcatactt gatattggtt
    11941 gaaaccgaac taatattggt ctccatcaaa atcacacgat agatttcttc ctgcccatag
    12001 ctattaaaaa cctgaatctg gtagatatgt cctagttctt tcttttctaa cttaatctta
    12061 tccaagccca aaaatcgatt tccagaaaga agttgagtaa agtctttatc aaagagaatg
    12121 acttccgtat tggaactgac attaggtttt atttctactt tactagcgtc cgccctagca
    12181 ttttctaaat ctttaatctc ttctgttgcc ctatttatag ccagctgaat aactgcttga
    12241 ggattttcac tcagtccatg aagcttatcg tccaccgaag tataaagact cgaatgcatg
    12301 acttgtaaaa taatcagagt cattgtagaa aaaatcaggg tgaagacacc gaagttgcgg
    12361 ataaaataac taaagtcatc cgcataccat gtttttttaa gtttactgaa catcttttaa
    12421 aagataccca acactacgca aggtttgcaa attctctgca aaagtggttc cctttaattt
    12481 cttacggact tttgaaacat agacttcgac aaccgaaatc gttgtatcac tatcaaatcc
    12541 ccatagacgg tcaaaaatct gcgtcttagg caaaatcaca ttttgatttt gaaggaaata
    12601 aactagtaaa tcgaactctt tccccagcaa ttcgacagga gtatcttcaa ctttaacggt
    12661 attggttgat aaattaacca cgatattccc ataagtcaag gtgttttcat taaacttccc
    12721 tgaacgtttg agaagggcct gaatccgcat tttaagttct tctaggtaga aaggtttggt
    12781 cagataatca tccgctccca gttcaaatcc atgtcccttg tcatccaaac tttccttggc
    12841 agtcataatc agaactggtg tcgtaattcc cttttcacgc aattctttta agacttggaa
    12901 accatttttt tctggcaaca tcaaatccag caaaatcaag tcatagacac cactctcagc
    12961 ttcgtagaga ccttcttctc catcaaatac ctgcataaca tccgcaaaat cgtctaaaaa
    13021 gtcaaatact gaatttgaca gacctaggtc atcctcaacc aataagattt ttatcatgag
    13081 aaactcctcc ttattaaaac tattatacca aatttgcctt aaaaaaaact caactctctg
    13141 cattttacat gagatagctg agttttcttt ttattttagg cttatttatg catttccgta
    13201 ttgaagaaca actgcttcga ctgcagcttt ttcacggcta atcaagtcaa cacgtgctgc
    13261 aatttccttg attcccatac cgatgttacg gctaagagca aggtcagaaa gttgcggctc
    13321 aaagaactcc ttgtattccg ccaagcgttg ctgagtctta aatacatgag caggaaggat
    13381 aacaaagcta tcaaagctca tatctcctcc aagggctgcc ttaatccaag cccagttttc
    13441 acgcgcccaa gaccaagctg ttttctgagt tgcttgatga gctaggaatt ggtaatacca
    13501 agcagacaag tcctgtggtt tgaccacaaa tttgtccttc caagaagtaa tcaagttttg
    13561 gatattatcc gcatctgtac tgtatgcaag agctgctgcc aactggcgtt taaagacagc
    13621 atctgttgcg tgagtataag tatcaagata aagtgctaac aagtctttag tctcatgatg
    13681 tttcatctca ttaatcagaa cttgtgaacg aatagctgct gggagttctg caagattctc
    13741 cttgtgtgtt gcgaagattt ggctagcgac ttgacgagct tctgcatcat ttgagcgaat
    13801 catcatcgaa acagccagct gacgaaccaa ttcatcctca tctgattctc cgtctttagc
    13861 ttcaaaacca agacggtcat agttatgacg agccaattta gcaaccagtc ctttgaaggc
    13921 tgtttcagca tccgctcctt catcaataaa gcgctcaagg gctgaaatca cttgagaaac
    13981 agctgaaacc accagataag actcttcctt agcaagttta tcaagaactg gaagcaagtc
    14041 tgcataagaa atgtgccctg cctcagccaa caaacgacgt tcttgaacaa tttgcagttt
    14101 gcttgtgtta tcaagtgtct ctagctcagc aagaacagct tctaacaagt ctccttgata
    14161 gtcggtaata tagtgggcag tattttcagt gttgagacga agagctcctt cattttcagc
    14221 aagaagagct gcgtagccag ggatttcgat actttcagtt tcgagtgtat caggcaagcc
    14281 tttccagttg ctattgaggg gcaccaccca gagacggttc ttgtcttcgt tctcaccgat
    14341 gaagaattgt ttttgtgaaa tcttcaagac atcattttca actttgacag taagaactgg
    14401 gtaaccaggc tgttccaacc aagaatccat gaaggctgcg acatcacgtc ctgacgcttg
    14461 accaagggca tcccaaaggt cactaccaat ggtgttgctg tattggtgtt tttcaaagta
    14521 ggcatgcaaa cctttagcaa aatcagcatc tcctagccaa cggcgaagca tgtgcatgag
    14581 acggcttcct ttggcataga cgatagcgcc gtcaaagagt gtattgattt catctggatg
    14641 tttaacttcg acgtggacag actgaacgcc atcagtagcg tcacgttcaa gagcaagagg
    14701 tactccacct gtttggaaat cttcaaagat attccagctt ggttcgatgg tatccacaca
    14761 gacgtattcc atcatattag cgaaactttc attgagccaa aggtcatccc accatttcat
    14821 agtcacgagg ttcccaaacc attggtgagc caattcatgg gccacaacaa gggcaacttg
    14881 ttgacggcta gcaaatgtag agttctcatc gacaaccaag taaacttcac ggtaggtcac
    14941 aagaccccag ttttccatag caccagctga gaagtcagga agggcgatgt ggagagattg
    15001 aggaattgga tacttaactc catagtaatc ttcgtaaaac tcgatagagc gaacagcgat
    15061 atccagtgag aaatcaagat ttgaaagtgg atgtgctttg gttgagtaga cacctaccag
    15121 ggtaccattt ttagttttag cggtcacccc ttgcaaatca ccagcaacaa aggccaacaa
    15181 gtaagaagac atgcgaggtg ttgtctcaaa cttccagata cctgtttcct tacggttttc
    15241 aacagcgatt tctggcatgt ttgacaaggc caattcacct tctgcttggt caaagcgaag
    15301 agagaggtca aaagttgctt tggcttcagg ctcatccaca catgggaaag cttcgcgcgc
    15361 aaaatggctc tcgaactgag tagacaagac ctccttcttg actccatcaa ctgtataata
    15421 agaagggtaa atccctgtca tgttgtctgt aattttacca gaaaaggcaa gaaccaattc
    15481 aacttgacca gcctcagcca attcgatatg aagggcttca ttgtcatggt caactgtaaa
    15541 tggacgagct tgacctgcaa cttctacaga ggtgatttcc aagtcttttt ggtggaggga
    15601 gatgcggtca ctctgtgctt gaccagtgat ggtcactttc ccagaaaaag tcttggtctc
    15661 acgactcaaa tctaaaaata aatcataatg ttcaggaaca aattgcttaa taaaatgttc
    15721 aactgcttgc atagttttct cctattctaa gtttaagagc tgctgctctt cttcaaacaa
    15781 acttattata tcatattttg cttgaaaaaa aaggattgga cagcgatttc caaaactttc
    15841 ttccttctaa tagtctacag tgggtagacc ttgcgaaatt cttctaaaac aaccttgctt
    15901 tcagatgtaa aagtcagccc tacttcaccc aaacagtctg tgaaaaagtc ctcatgaacc
    15961 tggcgccaat aggcaagtga tttgtctccc tcaccttcct taaaggcatg ttgcgcagaa
    16021 acttgattga agagttcaac agaaaccttt gtaatttcga caatgcagac agactgattt
    16081 tgactatcta aaatgatatc gaaggtccct acttggggaa gtggttcgtc ttctagtaca
    16141 tagaggtcat aggctgatgc tgttgctgtc ttttctcctt taaacaccaa atccgctaaa
    16201 agatctggtt caactccaaa agcccaagca tcgatttcat ctccgatcaa aggattgatt
    16261 tgcttgtatt tattccacat ttcttgcggt atcatgggta ctcctttgta attttttact
    16321 ttcttctttt atgtgtttaa gatgatctgg atggtcaatc tctaaatcaa aaatctctgg
    16381 aatagaactg tagtggataa tgcacttgat acccaactga ttcatttttt gtatgaaaga
    16441 agtattcaga tagcctgcta cagcaaaatc aatcttgttc tttcttgctt tatcctgcat
    16501 atctcttagc atatctaaca ttattggact ttccatatca tgccattgac tgtttctcat
    16561 agtcgcaaaa acaaaggaag tcaaatcatt cattccaact acaatctttg aaatgcccgt
    16621 ttccagtata ctagataagt caaaatacgc tgacggtaat tcaatcatcg ttccgacttt
    16681 cccagtaaaa ccctgctgac gcaatactgt aatagcttgt tttaattggt cgtcatcatt
    16741 gacaaaagga aagataacag atagattggg gttggtttga taaacttctg taacgacatg
    16801 tgcttcagcc tgaaattcat ccaaacacgc cagtaaacgc ctggttcctc tatagccaaa
    16861 caagggatgc ccttcgtcaa aaaactctct agtccccact aaacaattgg cttctgtatt
    16921 cgttaattca gaaaaacgat accaaacttc ttcatctgag tacagggagc agatagtctc
    16981 tagataatct tttacaaatt gctgacaact tgctaatatg atgttttgat taagctctct
    17041 caacaaatat tccccacgaa tcatgccgac gtggtgaaat agttgaggat aaattttttc
    17101 aagaattttt tcgccactaa gggcaagttg atttctcata gccattcacc tcgtcttaaa
    17161 agatacaata tcatatataa ttatatcaaa atttcctcta gttcaaaagc ttcataaggt
    17221 tcagataact catatcctaa aaattctgct acttttttgg aagcctcatt atgagcatcc
    17281 caaagtggaa acatatctct atttaaactc tctagaatca ttgcagcacc aagcttttta
    17341 gcaaatccat ttccttgttc gtttggtcta gttgcaactt ccacttcaac tgctttacgg
    17401 taaactaacc ctgaggaaat cccagcaatc agttcattat ttttaagaat cacaaagcca
    17461 aatccacctt ttaaaacaaa atcctgatag gactcaaaat ccccctgtaa atcctgtgac
    17521 cattcttccg tagaaaagca gttataaata tgattatcaa taggcacaat attgtaacct
    17581 tcctctaaat gagtaactag attatttaaa aattcaactt gaaaatttgc cttatcttta
    17641 aaagaatagc gagtaaaaga atttagcccc acttttcgat gcagaaaatc ttgccaatta
    17701 gtattttctg aaataataat cttataatct aaaccatatt ttctaacaaa atcttcccaa
    17761 aatctggaat ccaactcccc tgctaggtat agaaaattcc caacatcata aaagcttgtt
    17821 gtcctatcat tgtttcggta gacagttcca atttgagatt taagaccata gagaaccata
    17881 tttttcttcc atgttttaaa tagttccatt atccctctac ttcaccttcc aattcatgta
    17941 agaagtcttg tccagttctg gcaatcctaa taattcagac ttaaccttca agactaatgg
    18001 cgatgcattt tcttctgtaa tctcttgaat atccatccaa atatatccaa gtgaatcatt
    18061 cgcaccatca gacacagctt ccgaaatcgt aacttgaggt gcactctcat tcatttcaac
    18121 atcatacaag gctatgacat ggtgaaccat aaaatttttt aactcttccc tgacgaaaac
    18181 atcgtagatt cgaggattag agtagcttct aacagtaaat cccgtctctt ccataacttc
    18241 tctagtcagc gtttccgtca gtccttcacc aagttgctga ctgcctccag gtagatcata
    18301 ccgatgttga taagggcctc tcgttttttc aatgcaaagt aactttccat tttcaaagca
    18361 aacacagtag accccaaagt gatttttgat ttccatccaa ctcctcctac ttcaaagacc
    18421 agccaccatc tattgtcaga atttgtccct gcatggcaga tgcctttcca ctggccaaaa
    18481 agagactgac ttctgccact tcctctggtt caatccagcg cttgattggt gtttcactaa
    18541 ccacccagtc agctaagcca cctgtctcaa aatccgcagc ggtcatagct gtcttgactg
    18601 ctcctggagc gataccaaag acctgaatcc cagcttcagc atagtctaga gccaactgct
    18661 tggtgaagcc agccaaggca tgcttggatg aagtataggc gtgaccacct ccacctgcta
    18721 ggctagaagc aatggaacac atattgatga tgattccctt tttattttcc agcatttgtg
    18781 tcaaataata ccgagtcaac tctactggaa taatgtagtt gatttcaaaa atctcttgaa
    18841 tgtcctgcgc cgtttgttcc aacagtggtt tgtaatcatc caaaactccg gcagtattac
    18901 acaaaacatc cacctgaggg caccagtcaa aaataggttt caagtccaag gtcaaatctc
    18961 tctgtaaaaa gtgaaaatca ccctctaaga gtggcttttc accttggtca actccataaa
    19021 cttgatagcc cttctctaaa aagaggcgag cttgagccaa tccgatccct gaactcactc
    19081 ctgtaatgag tacacgttta gtcatgcact tctacccaat ccgttgccaa aacatcacaa
    19141 actgtcgggc tccacatgga aaaaccttct ccttcgccag aaacgttgat taggaaataa
    19201 ggtgtcattt caagtgcaag cccattttgc tcgatggtat caaagagttg gacatagttt
    19261 tccgcacctc cccaaccagt tcgtacatat tttctcttag cctttaaccc aggcaggatc
    19321 tcttcaaatg tcatgttttt ctcctttaat tctacattct tcatttaatt ataacaaaaa
    19381 aaccgcttta aaacggcttt ttgactgtga tttatttaca tcttcttcta cttacggcaa
    19441 attattccct gcagcaagat aaatttcata ccattctttt cttgttaagc taaagtttgc
    19501 cgcttggcta acttctctca agtgcttagg atttgtggta cctacaactg cctgcatttt
    19561 tgctggataa cgcaatatcc aagaaatggc aatagttgaa gaggttactc catatttaat
    19621 agctaaacga tcaagtactt gatttaaagc ttgaaatttc tcatttccaa caaaattccc
    19681 tttaaaatac ccgaattgca agacagacca tgcttgaatg accacatcgt gtaattggca
    19741 atattcaaaa atgctgccat ctcgcatagc tgcttgacta tcttccatat taacatgaaa
    19801 agctgattca aatcctggag taaaagccgc actcaattgt agctgattaa cagctaacgg
    19861 ctgcttgaca tcttttttaa gcaactccat catcatagga ttttgattag aaactccaaa
    19921 atctcgaact ttaccttgtt tataaaggag attaaaggct tctgctactt ggtcagattc
    19981 catcaaagca tctggtcgat gaaggagcaa gctatctaga tgatcaatct tcaatctttg
    20041 caaaataccg tctactgatt ttataatata gtccttagaa aaatcaaaat aggtaaattc
    20101 ttcaatgcga atgccacatt tggactgaat ccacatcttt tctcttaaat ctggacgatt
    20161 ttttaggaca agacctaaca gttcttcaca acgaccacga ccataaatat cagccaagtc
    20221 gaaggcattg attccaacag aaagtgctgt ttctgcaagc tcttcaactt cttttacaga
    20281 cttatctttt attctcatca ttccgagaac aatttctgat aattctttgt catcttgacc
    20341 aagagttatg tatctcatca aatttttctc ctttaatttc taacattctt cccttcatta
    20401 taacaaaaaa ccgctttgca acggcttttt gactatactt cactccattt tatcttctta
    20461 aacccacgga acaagacaaa gattccaata aagaggacag ctaaaggaat aacttttgta
    20521 aggaaaacat ttgaaattcc catccactca taataacgga gcagagaacc caccacaaga
    20581 tgggcaataa tcatactgac aaatggacga aagaccgctt ctttccaatt ccaaataccg
    20641 ataactagcg aaatcgtaaa gacagacaaa ctatcccagg gagccggaat ataaaaggct
    20701 ccttcttgta tgaagcttgc cattcctaca tatcctaaaa caactagaag aactatagtc
    20761 ccaacaacaa tgtaagtgcc aattttcatt ttaggagaat cttggactaa acttcttcgt
    20821 aaaattgtgg ccacaagtcc aaatccaatc agaaaaataa gaagttgccc taaaaatgtg
    20881 agcaaattga ctgttaagag aggaccttta gaaaaatcac ttagtagttg ataataacgt
    20941 aataccgcca ggacaagaat tggcgtcaaa agggactctt tgatagaact gcgaggtgct
    21001 cccttgagaa tctctttcat tattttttta ggattcttac ctagataatc ctctgcactc
    21061 atgccatctc gttctgcttc tgagaaatct agcatcatca aatagatctg ctctctgaga
    21121 tagtcttcat catagagaaa tccagcaaga ttaaaacttt cccacaactc ctcaaaatac
    21181 ttttgattct cctcagaaaa ctcatgtagc aaagcgcttg tttcttcgta atacttcatt
    21241 ttcttcatgg tttaaccccc attcttaatc ccttctactt tttgactcaa atcgtcccat
    21301 tgttgccaaa agactgagac acgctcttct ccttctttca ttaatgaaaa atacttccga
    21361 tctggaccat ctggcgacgg gcgcatgtcg cctcttatcc attgattttt ttctaacttt
    21421 tgcaacaaag gataaatagt tcctggaacg atagtatcaa atccagcctc tcgcaaagtc
    21481 tgaaccaact cataaccata ccgctctttt tgaccaatca tatccaagac acaaccttca
    21541 agaacacctt ttaatagctg agtttctttc atcacttctc ccttctaatc tattttgtaa
    21601 tacctactag taacttcacc tatagtatat cacttctaca ctagtttgta aagcataata
    21661 gttaatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccctaccg tatgtatggt
    21721 tactgacttc gtcagtttca tctacaacct caaaacagtg ttttgagctg acttcgtcag
    21781 tttcgtctac aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttgct
    21841 ctttgatttt cattgagtat aaataaaaaa acagaactag cctgaactag tcctgtctac
    21901 ttttacccaa tcacacttcc atttggtaca gctggatcaa ctgtgagaag ggttaatttg
    21961 ccatcatgtt cagctgagag aatcataccc tggctgacat attttttcat cattttacgt
    22021 ggtttgaggt tagcaacgat ttgaactttc ttgccgacca attcttgttc atttggatag
    22081 tattttgcaa ttcctgaaag aatctgacga tcttctccat caccagcatc caagcggaat
    22141 tgaagcaact tatctgaacc ttctacttta gacacttctt tgacttctgc gacacggatt
    22201 tcaaccttgt caaagtcttc aaacttgatt tcatccttgt ttagtttgag ctcaacttcg
    22261 tccggattcc attctttttc gactgctggt ttattgcctt ccatttgttc cttgatatag
    22321 gcgatttctt cttccatatt tagacgtgga aagataggtg ttcctttggc aactacagtc
    22381 acatctgctg ggaagtcagc caaactcaag ttttcaagac tagaaacttc ttccaaacca
    22441 agttgagtca aaactgcacg actagtttcc atcataaatg gttcaatcaa gtgagcaact
    22501 acacgaatgc tggctgccaa gtggctcatg acacttgcca attggtcacg aagagcttca
    22561 tccttggcca agacccatgg tgcggtctca tcgatgtatt tattggtacg agagatcaga
    22621 gtccagactg cttcaagcgc acgtggatag tcaactgctt ccatgtgtgt atggaagtct
    22681 gcgattgatt gttctgcaac ctcagcaaga acatgatcaa attcagtcac accttctaca
    22741 taggcaggga tttgtccatc aaagtactta ttaatcatgg aaaccgtacg gttaaggagg
    22801 ttcccaaggt cattagccaa ttcatagttg atacggccga catagtcttc aggagtaaag
    22861 gttccgtctg aaccaactgg aaggttacgc atgaggtagt aacgaagtgg atctagtcca
    22921 taacgctcta ccaacatttc agggtaaacg acattccctt ttgacttaga catttttccg
    22981 tctttcatga caaaccaacc atgggcaatc aaacgatcag gtaatttaac atccaacatc
    23041 ataagaagga ttggccagta gatagagtgg aagcgaagga tatcttttcc taccatatgg
    23101 aagactgttc cattccagaa cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga
    23161 gctgtcgcat agttaagaag ggcatcaatc caaacgtaga caacgtgttt tggatttgat
    23221 gggacaggca ctccccatgt aaaggttgta cgagataccg ccaaatcttc caagcctggc
    23281 tcgatgaagt tgcgtagcat ttcattaagg cgaccatctg gcgtgataaa ttcaggatga
    23341 gctttgaaaa attcgaccaa acggtcttgg tatttgctaa ggcgaaggaa gtatgattct
    23401 tcagaaaccc attcaacctc atgacctgat ggagcaatac caccagtcac atttccagct
    23461 tcatcacgga aaacttctgc cagctggctt tctgtaaaga attcttcgtc tgatactgaa
    23521 taccaaccag agtattcacc caagtagata tcatcttgag caagtaagcg ttcaaagact
    23581 tgtgcgacaa ctttttcatg gtagtcatca gttgtacgga taaatttatc gtatgagata
    23641 tctagtaatt gccagagttc tttaactcca accgccattc catcaacata ggcttgaggt
    23701 gtaataccag cttcttccgc tttctgctgg attttctgac catgttcatc aagacctgtc
    23761 agataaaata catcgtagcc catcaggcgt ttgtaacgtg ctaggacatc acatgcgata
    23821 gttgtgtagg cagaaccgat atgaagtttc ccagatggat agtaaatcgg cgttgtaata
    23881 taaaaatttt tttcagacat aatttttcct ttccaggcaa atgaaacctg tttttctaac
    23941 acttcattat atcacatttt taatgaattt cgatagggaa atccatacaa aaacaagata
    24001 gacgagtgtc catcttgttg atctcattca taacgaaggg cttcaattgg atcaagtttc
    24061 gatgccttgt tggctggcaa gactccaaaa atcataccaa cactagccga aactgcaaga
    24121 ctaaataggg caactgggat tgatactcca acttctatac cttctattaa accttgcagt
    24181 aacaaacctg ctaaggcagt taaaccactt gcaattgtca agccaattaa gccacctaac
    24241 aaggtcaaaa tcatggattc aatcaaaaac tgaattaaaa tattggcacg tgttgcgccc
    24301 aaagccttac gaagaccaat ctcacgagtg cgctctgtca ccgaaaccag catgatgttc
    24361 atgacaccag ttcctccaac aaagagagaa atccctgcga tggaactaat aatcgtcgtc
    24421 ataaaactaa acgattgttg aatttctgca aatacaacgg actcatctgc cacctggtat
    24481 tctccctgtt gtaagcctgc aagctctgtc atttttcgtg ccagttctgg acccagagtt
    24541 ggggttaaac tggtatcatt cactcgaaag acaatactag ctatttcatc tatattaaaa
    24601 ttcgcagcaa gggagatatt ggtagtaata ggcaagccac caaacccata tatttttgac
    24661 cttttagcct ccggactagt ataaacccca atgacccggt aactaaatcc attgacttct
    24721 acaaccttgt taatagcctc ttgaggagat tcaaataaac taatggacaa ttcctcatct
    24781 agcaaaataa cacttgcaaa ctctttgaaa tcttgctctc tcagactacg acctgcaata
    24841 atttcattct taacagcgtc catgtaagtt ctgtttccac ctgtcaaatt agcattctca
    24901 acctttttat cttgataggt caagatggca ttcgttgaat tggttacata gtaactatcc
    24961 actcccttca gtttagctgc ctcttgaacc caggattctt gcggttttgg cggttcaaca
    25021 ggaacttcct cttcctttcc agaaaccgta aaagctgatt gtttctgagt aaaagaccca
    25081 tctttacttt ttttaggaga gaaaaagacg ctaatatttt tctgagattt agtcatatct
    25141 ttattgactt gacgagatag ggaatcaccc aaagccataa tcacaacaac tgatgaaaca
    25201 ccgataataa tcccaatcat agtaagcaaa gaacgcatct tgtgagccat gatagatgaa
    25261 aaggcaaatt tcagattctg catcttagtt ttcctccttt cctaactgag cactgtcaga
    25321 cgaaatgacc ccatcccgaa tgacaatctg acgtttggca taggcagcaa tctcaggctc
    25381 atgcgttacc atgataatgg tttttccttc tttattcaaa tcaaccaata attgcataat
    25441 ttggttacct gttttggtat ccaaggctcc tgtcggttca tccgctagga taatagaagg
    25501 attgtttacc aaggcacgcg caatggctac acgttgcttt tgaccaccag ataattctga
    25561 aggtaaatgg tgactacgtt ctgtcaattc aaccttgtct aaatattcct cagccaactt
    25621 gcgacgtttt gaagacgaaa ctcctgcgta aatcaagggc aattctacat tttgcagagc
    25681 attgagcttc gatagaagaa agaactgctg aaagacaaaa ccgatttgtt ggttacgaac
    25741 cttagctagt tgtttttcac caagcccagc tacttcttga ccttcaagat aatattctcc
    25801 actggttggt gtatccaaca tgccaatcgt attcatcaga gtggacttac cagacccaga
    25861 tggtcccatg atggctacaa attcaccctc attcacttct agattgatat ttttgagaac
    25921 ctgcagttct tggtcaccat tacggtagct tctgaagata ttttttagac taattagttg
    25981 cttcatcagc cttcacctct tttccttctt ccaaggaaga tgttggatta ctgatgacct
    26041 tagcaccgtt cgttaaacca gaagtgattt cttgattttc tgcgtcagca tttcccaatg
    26101 aaacctcaac ttttttagcc ttttgttgtt catccacaat ccagacataa tttttactat
    26161 catccattac tagactgcta acaggaacaa gaatagcctt agttttgctt ttaacctcaa
    26221 tgttgacaga aaaaccttgt ttcaaatcac caacctcgcc tgtcacatca atagtataag
    26281 ggtatttaga acctgtatta ttcccggctg ctggactagc tgcttcacca ttgtttttag
    26341 gatagtcaga aatatagctt aatttcccag tccatttttt atcaggatac actttagaag
    26401 taaagcttac ttcttgacct acagaaaggt tggctagatt gtactcagac aattctccct
    26461 tgacttgtaa attttcattg ctgacaatat gaaccataac ttgactcgcc cctgttggag
    26521 atttagaaac attgctattg acttcgacta cagttccctc tagggtactg agaacagttg
    26581 ttgcatccaa ttgactttga gccttgctta attgcgctgc agcatctgca cgcgcatcac
    26641 gggcatcacc caattgagca tcaatagaag caacagaatt tccagccact ggagttgggc
    26701 tttgcaccgt tgcatcttct cctcctactg gcgctggtaa ctgtggagcc tgagctgaag
    26761 cggcttcatt tcgtgcttga ttgagttcat tgatatgacg atctgcctta gctactgctc
    26821 gactagctga atcataggcc gcctgcgctt ctgaactact gtacttgact aaagcctgcc
    26881 cttcgctgac cttatcgccc acagaaacaa ggatttcatc taaatcaccc ttactagcat
    26941 caaaataaac atattgttca ttttttgctg ttactgtccc tgacaataaa acagaggatg
    27001 ccacgcttcc ttccttggca acaacaagat gagtaggctc atcttttaca gcagtctgag
    27061 aaggttgtct aaagagtaaa atccccccgg cacccaatac aactacactc gcagcaccaa
    27121 ttgctgcata cagttgccac tttttagctt taccattctt tttcttcata atgaaactcc
    27181 ttttcttttt tacaatactt tgctattata ccaaatttcc ctccagcaaa caatacagtt
    27241 caggattaag caatcgttcg gaatttttct tttctattgt actagatata taatacacca
    27301 tcttgactta tttggcaagc ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca
    27361 aatcaaaaaa agaataaaat ataactatca aaaaagacgc tctactattt aaaagattac
    27421 aaaggagttt tcaatgagag aatatgatat cattgctatc ggtggaggta gcggaggaat
    27481 cgctaccatg aaccgtgctg gtgaacatgg agccaaagca gccgttattg aggaaaagaa
    27541 attaggtgga acctgtgtca acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc
    27601 gcaaatcgct gagactttcc atcaatttgg agaagactac ggctttaaga ctactgatct
    27661 taactttgac tttgcaaccc tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc
    27721 ttcttatgat ggtagtttta aacgcaacgg tgtagacttg attgaaggtc atgctgaatt
    27781 tgtagattct catactgtaa gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat
    27841 tgctacaggt gcccatccaa gtattcctaa tattcctggt gctgagctag gtggctcttc
    27901 tgatgatgta tttgcctggg aagaacttcc agagtcagtt gccattctag gcgctggtta
    27961 tatcgccgtt gaattagctg gcgtactcca cacttttggt gtcaagacag atctctttgt
    28021 tcgccgcgat cgtcctttac gtggttttga ttcctacatc gttgaaggtt tggtcaagga
    28081 aatggaaaga ataaacttgc cacttcatac tcacaaagtc cctgccaagt tagaaaaaac
    28141 tgctaaaggc attaccattc atttcgagga tggtaccagt cacacagcta gccaagttat
    28201 ctgggctaca ggtcgccgtc caaacgttaa gagcttgcaa cttgaaaaag ctggagtgac
    28261 tctgaatgaa cgtggcttta tccaagtaga tgaataccaa aatactgttg ttgagggaat
    28321 ctatgctcta ggtgatgtaa caggtgaaaa agaactgact ccagttgcaa tcaaggctgg
    28381 gcgtacccta tctgaacgtc tctttaacgg aaaaacaact gcaaaaatgg attactcaac
    28441 tattccaact gttgtctttt cacaccctgc tatcggaact gttggtttga cagaagagca
    28501 agctattaaa gaatacggtc aagaccaaat caaggtttat aaatcaagct ttgcatctat
    28561 gtactctgct tgcactcgca accgtcaaga atcccgtttc aaactcataa caactggttc
    28621 agaagaaaaa gttgtcggac ttcatggaat tggctacggc gttgatgaaa tgattcaagg
    28681 atttgccgtt gctatcaaaa tgggagcaac caaggctgac tttgatgcaa ctgtggcaat
    28741 tcacccaact gcatctgaag aatttgtaac catgcgttaa tcgaaacaaa agaagctgat
    28801 ataaatatgt ctgcttcttt tttaatgatt ttcgaatcaa caaaaaaatt atccaacttg
    28861 actagtcacg aaaatcggct gttacagttt ttgttacctt gtttttaaaa aatggttgac
    28921 atcgactcct atatgagtat aatagttact atacattaga aaagaggtta actattttga
    28981 aaaaagctca cgtttatgct atccctgcta ttggggctgc tctcattgct gttttggcac
    29041 aaatcagtct tccaattgga cctgttccct tcactctgca aaactttgca atcggcttga
    29101 ttgctactgt ctttagaccg agagaggctg tactttctgc tggactctat cttcttctag
    29161 gtgctatcgg tcttcctgtc tttgcaggag gtggagctgg ttttcaggct ttagttggcc
    29221 ctactgcagg ctatctttgg ttttatctcg tttactctgg acttacttcc tctctaacca
    29281 acagcaagag tggtgttgtt aagatttttc ttgcaaacct cttgggtgat gcccttgtct
    29341 ttgtcggcgg gattctcagc ttgcatttcc tagctggaat ggcatttgaa aaagctcttg
    29401 ttgtgggagt tcttcccttt atcattccag accttggcaa acttctggct attagtttta
    29461 ttagccgtcc cctacttcaa cgccttaaaa atcaggctta ctttactaac taaaaaagga
    29521 taccgagtta tcatgactca atatcctttt ttttattttg aaaacttata ctcaatgaaa
    29581 atcccggctc tttgtcaact gtagtgggtt gaagtcagct aagcttgaga aaggacaaat
    29641 tttgtccttt cttttttgat
//
LOCUS       DAVHBD010000027        28528 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000027 DAVHBD010000000
VERSION     DAVHBD010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.027"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(62..1387)
                     /gene="brnQ"
                     /locus_tag="VVK04_001277"
     CDS             complement(62..1387)
                     /gene="brnQ"
                     /locus_tag="VVK04_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU3989933.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(1558..1650)
                     /locus_tag="VVK04_001278"
     CDS             complement(1558..1650)
                     /locus_tag="VVK04_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU3989934.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(1693..1845)
                     /locus_tag="VVK04_001279"
     CDS             complement(1693..1845)
                     /locus_tag="VVK04_001279"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU3989935.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(2005..2583)
                     /locus_tag="VVK04_001280"
     CDS             complement(2005..2583)
                     /locus_tag="VVK04_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU3989936.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(2637..4037)
                     /gene="pepV"
                     /locus_tag="VVK04_001281"
     CDS             complement(2637..4037)
                     /gene="pepV"
                     /locus_tag="VVK04_001281"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU3989937.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(4050..4655)
                     /locus_tag="VVK04_001282"
     CDS             complement(4050..4655)
                     /locus_tag="VVK04_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU3989938.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            4826..5626
                     /locus_tag="VVK04_001283"
     CDS             4826..5626
                     /locus_tag="VVK04_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3989939.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIVFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(5808..6641)
                     /locus_tag="VVK04_001284"
     CDS             complement(5808..6641)
                     /locus_tag="VVK04_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU3989940.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKDFFDF
                     L"
     gene            complement(6631..8475)
                     /gene="uvrC"
                     /locus_tag="VVK04_001285"
     CDS             complement(6631..8475)
                     /gene="uvrC"
                     /locus_tag="VVK04_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU3989941.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(8515..9216)
                     /locus_tag="VVK04_001286"
     CDS             complement(8515..9216)
                     /locus_tag="VVK04_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU3989942.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(9295..10527)
                     /gene="murN"
                     /locus_tag="VVK04_001287"
     CDS             complement(9295..10527)
                     /gene="murN"
                     /locus_tag="VVK04_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU3989943.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(10532..11752)
                     /gene="murM"
                     /locus_tag="VVK04_001288"
     CDS             complement(10532..11752)
                     /gene="murM"
                     /locus_tag="VVK04_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU3989944.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAI
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPMLRL
                     ALDFRKTLRKKHRK"
     gene            complement(11864..12643)
                     /locus_tag="VVK04_001289"
     CDS             complement(11864..12643)
                     /locus_tag="VVK04_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU3989945.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYMALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(12712..14373)
                     /locus_tag="VVK04_001290"
     CDS             complement(12712..14373)
                     /locus_tag="VVK04_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU3989946.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(14548..16770)
                     /gene="recJ"
                     /locus_tag="VVK04_001291"
     CDS             complement(14548..16770)
                     /gene="recJ"
                     /locus_tag="VVK04_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU3989947.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSIPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEAMDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQILEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEVSFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMMDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            17047..17805
                     /locus_tag="VVK04_001292"
     CDS             17047..17805
                     /locus_tag="VVK04_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU3989948.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            17845..18609
                     /locus_tag="VVK04_001293"
     CDS             17845..18609
                     /locus_tag="VVK04_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU3989949.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSDYSIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            18622..19299
                     /locus_tag="VVK04_001294"
     CDS             18622..19299
                     /locus_tag="VVK04_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU3989950.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISALRLIILPQAFRIILLPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPGFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            19309..19968
                     /locus_tag="VVK04_001295"
     CDS             19309..19968
                     /locus_tag="VVK04_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU3989951.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            20263..21453
                     /locus_tag="VVK04_001296"
     CDS             20263..21453
                     /locus_tag="VVK04_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU3989952.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGNKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(21774..22655)
                     /locus_tag="VVK04_001297"
     CDS             complement(21774..22655)
                     /locus_tag="VVK04_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU3989953.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYDDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(22796..24124)
                     /gene="vncS"
                     /locus_tag="VVK04_001298"
     CDS             complement(22796..24124)
                     /gene="vncS"
                     /locus_tag="VVK04_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU3989954.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(24121..24777)
                     /gene="vncR"
                     /locus_tag="VVK04_001299"
     CDS             complement(24121..24777)
                     /gene="vncR"
                     /locus_tag="VVK04_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU3989955.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(24826..24909)
                     /gene="pep27"
                     /locus_tag="VVK04_001300"
     CDS             complement(24826..24909)
                     /gene="pep27"
                     /locus_tag="VVK04_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU3989956.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(25089..26468)
                     /gene="vex3"
                     /locus_tag="VVK04_001301"
     CDS             complement(25089..26468)
                     /gene="vex3"
                     /locus_tag="VVK04_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU3989957.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(26520..27167)
                     /gene="vex2"
                     /locus_tag="VVK04_001302"
     CDS             complement(26520..27167)
                     /gene="vex2"
                     /locus_tag="VVK04_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU3989958.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(27180..28457)
                     /locus_tag="VVK04_001303"
     CDS             complement(27180..28457)
                     /locus_tag="VVK04_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3989959.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         8168 a         6532 c         5303 g         8525 t
ORIGIN      
        1 atcatcggat aaaaaaagaa aatcactcct gtagacttgg ctacaaaagt gatttaagtg
       61 attattccat ttcaaaaaca tcgctttctt gcttgtttgg tagaaccaat gagagcaaga
      121 ttccaacaat ggctggcacc aaccatggga gagatgcctt ggcaaaagga agaacgctaa
      181 caagatttgc aagaaactca accttaaacg agcttcctag tacgcttgca atggcaataa
      241 ctgtaaccac agcaattgtc aactgcatac ctggttttga aagggcaaca aatttgttga
      301 caatgacaat cataacgata gcaatcgtga ttgggtacaa gataaccaat actggaattg
      361 agtacttgat aatcgcatca agacccaaat tggcaatagc aaatccaatc aaggtaaagg
      421 ctgtcgcata aaccttgtag ctgatttgtg ggaagcgctc attaaagaac tcagctgttg
      481 acacaatcaa accaacagtc gttgtgaagc aggttacggt aaccatagct gcaaggaaga
      541 gttgagctgt tgagccaaag atttcttgag tggcttgtga caagatgtaa acacctggtg
      601 ttccaccctt catcgcttca gctggtactg ggaaatgatt tccaagaaaa cctaaaccga
      661 tgtaaagagc gctgaaggca agggcaacaa cgataccaac aacccaaata gttgaaatgt
      721 attctttctt acttgaaaat ccaagttgtt tcaaggtttg aactgcgatt acgctaaagg
      781 ccactgaggc aagggcgtcc aaggtattat aaccttctag gaaacctgta ccaaaggcag
      841 aagcttgata agcagctgaa gcagcttgag gacttgttcc accatatttg atagctccca
      901 gaacgaccaa gataacaatc aaaattgcaa agactggcgt taaaatacgt ccaatgcggt
      961 ctaagatttt tgatggatta agcgaaatca aataggctgc cgcaaaatac agaaccgtaa
     1021 atacaatcaa gccaagtcct ttatttgcat ccgacaaaag ggggctaatc cctacttcgt
     1081 aagctgttgt agcagtacgt ggggtagcaa agaatggacc gattgacaag taaagaactg
     1141 agaggtaaag agtcgcaaac caaggcgcta tcttcgttga aatctcgtag atatatcctt
     1201 taggatttag cgttccaata ataagggtca agacggcgat accaacgcct gaaaagacaa
     1261 aacctgcgat ggcaggaaga aaatgttctc cagatagagc acctagagaa ggcggaaaaa
     1321 tcaagttccc cgcaccaaaa aatattccaa acaggagcaa acctgttagg gtaccttttt
     1381 tagccataaa aatctccttc atatttataa aatactgacc tagtatacca cgattaggag
     1441 tctgaaaaaa gcatcacgag gcaaatatta aatgttttca attttcttaa aaataagaat
     1501 tatctaaaaa taaaactctc ctacccagtc cacaccaagt aggagaaatg caaaatttta
     1561 aagttcttca aaggctaaca tgccaccctg gacattgata acattataac cttgttctaa
     1621 caggaattgg caagcacgcg ccgatctcat tccagatttg caaataatat aatgcaagcg
     1681 atctttgtcc aattaatcat aactatcagc caattgacta agcggtaggt tgtgggcaca
     1741 ttctaaatga agagctgcaa actcatccac ttctctcaca tccactagag aaagctggtc
     1801 gttttggtaa agctggtaaa atgcgtcaaa ggctatttct ttcattcttt ttcttctaat
     1861 actcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtgcgta tgttaccgac
     1921 ttcgtcagtt ttatctgcaa cctcaaagct gtactttgag cagcctacga ctagcttcct
     1981 agtttgctct ttgattttca ttgactataa aatggtttta attctttttt tcaaatctgg
     2041 cactacttct gcctcaaacc aaggattttt ggccatccag atttgatttc gtggtgatgg
     2101 gtgaactagc ggaaaatagg ctggcagata gtctttatag tgtttcaccc tctccgttac
     2161 cttcccactg attttctcct gtaaatagta ggcttgggca tattgcccaa tcaagagggt
     2221 taactgaata tcaggcaatt cctgtaagag ctgcggatgc catttttctg caaaacctgt
     2281 acgaggcgga agatcacccg acttgccatg tcctggaaag tagaaatcca taggcaaaac
     2341 agcaaaataa cctgaattgt aaaaggtatc ttcatccaca cctagccagt cccgcaagcg
     2401 gtcaccactt ttatctttcc agtaaaggcc tgcttcttga gttttaagtc ccggagcctg
     2461 accgatgata ttgatgcgag cagtttttgg cgctgcaaag agaggctcaa tgccacgctc
     2521 tgtatagctg gcattctgtg aatccgccat gatagcctgt ttgattcttt cgatttgaga
     2581 catctacttt ccctccaaaa agaagtccaa gcataagatc tcagacttct atcgttttat
     2641 ttgatcaatt cgtaaatagc ttcggcataa attgctgctg ctcggaaaag atcatccaag
     2701 gcgataaatt cattggcttg gtgcatggta tcaatcgagt ctgggaacat agcaccgtag
     2761 gcaactccgc gttctagcaa gcgaccaaag gttccaccac cgatgacttg ttcatgacct
     2821 ttaaggccag tttgtttttc atagatattc aacaaggttt gcacaagtgg atcttccatt
     2881 ggcacatagt gaggcgtgtg accgtgttca gacaggctaa cagaaacaac tggcaagttt
     2941 tcaaggattg acttgatttg ttctggactt gttccttttg gatagcggat gttgagggca
     3001 atggtattat cagcacttgt ttcatcgaag cggaagacgc cggcattcat agaaagagca
     3061 cccatctttt catccacatg agcaatctta agattttcac cctcatgatc gttcaagaga
     3121 attttacctg cgatgtcaag gtagtctttg gctggaccag caaagccaaa ctggctgagg
     3181 aagagggcaa ggtaagttgc gccattgaca cctgaagcag gcatagcacc gtgggctgat
     3241 ttaccaatga tcgtcacctt gtatttgcca gcttcttctt ggagttctcc tctaagtttg
     3301 tgttctgcaa caaaggcatc tagtttagct tgcaagtcag ccaagtcacc tgaaacgact
     3361 gctgttgctg attctggtac catattttca cgtaaaccac ctgtaaagct gtgaagacgg
     3421 gcaacacctg tattttctcc tgcaaagtgg aggtattccg tgatatttcc tttttcacca
     3481 ttgatgattg gaaattcagc atctggtgag aaaccgaaat ctggtttggc aagtcctacg
     3541 tgctcaaagt agtagtccat gtctgcccag cctgattctt cgtctgttcc aacgatgaag
     3601 cgaactttct tagaagttgg aagacccaat tctttgatga ttttcaaacc atagtaacaa
     3661 gctgttgtag gacccttatc gtccgaagcc ccgcgcgcat aaaggcgacc atctttgata
     3721 gttggtgtgt aagggtctgt gtcccaaccg ctaccagcag gcaccacatc catatgggca
     3781 aagattccga gaacttcttc tccatcacca aactcaaaat gtcctgcata gttatcaaca
     3841 ttcttagttg ggtagccatc gcggtctgcg atttcaagga atttctccaa ggcttttact
     3901 ggaccaggcc caaatggatg ctgggcatca gccttgctgt catcacgttc tgaattgatt
     3961 tccaaaaggc taaacaagtc agccaagagg tcttctttgc gtttttctac ttctgctgta
     4021 aaatcaattg ctgtcatttt ttcttctttc tatcttttct cgatgatttc atctactggc
     4081 aagcggtagc ttggttccaa tttttcgtct gtataaccca ctgtgatcaa gagttctggg
     4141 cggaaacggt cttcgatttc caaaacttca ttaacttttg atttgtcaaa accaagaata
     4201 atgttagaac caattccttg gtctgtcaat gcaagaacca agttcatggc aaccaaacct
     4261 gcattgagag ctaggtagtc gctgacttgt tgctcactgt aacgggcaaa ctcagctggc
     4321 agatttttca taaaatattg aagttgctct tcagaaaagt tattagcacc accaacacgg
     4381 gcaatcttac gagcacgttt ggctaagtcc gtatctgtaa acaaggcaat ggttacaggc
     4441 gctgatgata cctgttcaaa attggaacca taagctaact ttgccagttc agcatttttc
     4501 tcacgtacca ccacaaattt ccaaggctgg ctgttgtggg cgcttggcgc caaggttgca
     4561 atttcgatag ccgtacgcac atctttggga tcaacaggct tatcagtaaa atgcttagtc
     4621 gcatgacgtt ttttatttaa ttcaagaaat ttcataatcg atttcctttt ctaattctac
     4681 tgcttccatt ctaccataat ttgaaagagc ttgcagggat ttttcatgat taagtttttc
     4741 tatcacagac ataaaagata tatattggtt tatcaggaaa gtttctgata aactagcaag
     4801 tactttacat ttgaatggag acagtatgaa aaaatttagc ctattactag ctatcctacc
     4861 atttttggtt gcctgtggga atcaagctac acccaaagag actagcgctc aaaagacaat
     4921 cgtccttgct acagctggcg acgtgccacc atttgactac gaagacaagg gcaatctgac
     4981 aggcttcgat atcgaagttt taaaggcagt agatgaaaaa ctcagcgact acgagattca
     5041 attccaaaga accgcctggg agagcatctt cccaggactt gattctggtc actatcaggc
     5101 tgcggccaat aacttgagtt acacaaaaga gcgtgctgaa aaataccttt actcgcttcc
     5161 aatttccaac aatcccctcg tccttgtcag caacaagaaa aatcctttga cttctcttga
     5221 ccagatcgct ggtaaaacaa cacaagagga taccggaact tctaacgctc aattcatcaa
     5281 taactggaat cagaaacaca ctgataatcc cgctacaatt aatttttctg gtgaggatat
     5341 tggtaaacga atcctagacc ttgctaacgg agagtttgat ttcctagttt ttgacaaggt
     5401 atccgttcaa aagattatca aggaccgtgg tttagacctc tcagtcgttg atttaccttc
     5461 tgcagatagc cccagcaact atatcgtttt ctcaagcgac caaaaagagt ttaaagagca
     5521 atttgataaa gcgctcaaag aactctatca agacggaacc cttgaaaaac tcagcaatac
     5581 ctatctaggt ggttcttacc tcccagatca atctcagtta caataacact cttcgaaaat
     5641 ctcttcaaac cacgtcagct ttatctgcaa cctcaaagct gtgctttgag caacctacgg
     5701 ctagcttcct agtttgctct ttgattttca ttgagtataa gatatactaa aagcgattgg
     5761 accagccaat cgctttttta gtttgcattg gctattttag gaaactctta caaaaaatca
     5821 aaaaaatcct tcacatcctc tacataccca tgcttttcta ttaagctggc taataattcc
     5881 agattgtgcc cctgatagtt atcttcacga cgcagttctt catacatttc gataaaggga
     5941 agccccttgg acttggccaa ttctaactca gcttcgtaat cataagcaac tttacgaaat
     6001 tggatattga gtaattctcc atcttcaact tctatcacgg catactgggc acggtgattt
     6061 tttaacgcct cccaattaaa atagggcatg ccaatcgacc ctggattgat gatttgttgc
     6121 ccttgacttc cataacgaag caactgcttg tgaacatgac cataaactgc cacgtccgtt
     6181 tccgcatcta gtagttggtc aaatttctct gtatcattct caactagcaa gtcaccacca
     6241 tagtttttgt caggtaaatt atgagagata gaaaagcgca atccgtcaat ttctttcttt
     6301 tccagcaaag gcaagcttcg tagccagaca atcgttgcag gatccattcg ctccatcaaa
     6361 aactgggtca tacgcaagag ctgaacttcc tgtgggtctt ctaagccata ttgcccatct
     6421 aaagcctcaa ggacacgatc atcccaattg cctcgaacac ttgctgtgat aggaaggtcc
     6481 tttagcaggg cgactaagtc atttgcgcct ggaccaggaa gaaaaatatc tcccagaagc
     6541 caatattcac tggccccttg atttttagca tctgcaatca ctgcttctag cgccgtcgca
     6601 ttgccatgaa catctgataa aattgcgatt ttatggttca ttgtggtttc cttccgtttg
     6661 gtaatctact ctttcttctg ctacttgagg caaggcttct ccctgcgggt tcaactttct
     6721 ttgcacagcc tctgcaacga ctctaggtac cccaacttcg acaatctcat ccacactggc
     6781 ttccttgatt ttggtcaaag acttgaaatg cttcataaga ttctgcttgc gtttaggtcc
     6841 cagaccgtca atcccatcca attgagatga gaaagaattt ttggagcgca gttggcggtg
     6901 gaaggtaatg gcaaagcggt gcacctcatc ttggatgcgt tggaggagga aaaattcctg
     6961 agaattgcga gacaagtcca ccacctcaag cggatctcca aagagcaatt catgggtttg
     7021 gtgcttatca ttcttttgca gcccagcaat tggaatatcc aagcccagtt cctcttggat
     7081 aacctgctta gcgatattga cttgaccttg ccccccatca atcacaatca aatctggagg
     7141 agtcaaagcc tcacgctgta ctcgaccata gcgtctgcga atgacctctc tcatgctggc
     7201 atagtcgtct ggtccaacaa ccgtttttat cttgtactta cggtaatcct tcttactcgg
     7261 tttaccgttg acaaagacca ccatagccga aacagggcta gttcccatga tattagagtt
     7321 atcgaaggac tcgatacgta ctggggtcgg gatttggagc aaacgtccta gattttcaat
     7381 agctccttgg gtcttctcga cagatttctc tagcaggtta aatttctgct ccagactaac
     7441 acgtgcattt tttatggcta gattgaccag ctgttttttc tctccacgtt ggggtttgag
     7501 aatcttggta tccaccaaag ccttgacagc ctcttcgtca atatcctgcg gaatcagtac
     7561 ctcattggga actaggtgag atttttcttg atagaattgt cctacatagg tcaaaaaatc
     7621 ctcatctgga tcattgaagt aggggaagag attgacatcg cgctcgatga gcttaccctg
     7681 acggacaaag aaaacctgca cacacatcca gcccttatcc acatagtagc caaagacatc
     7741 gcgattttgg agatccttag ccatgacccg ttgcttggtt cgaagcgttc caatagcctg
     7801 aatcaggtca cggtattccg ccgcacgttc aaactccata gtctgggctg ccgctgccat
     7861 tttgcccttt agctcatcaa tgattttgtt atcctgccct ttcagaaaat cagaaacctc
     7921 ctgggccata gacttgaaat aagtctcatc cttcttacag atggtgtggg ccatgcattg
     7981 accgatatgg taataaaaac agaccttaga gggcgggttg gtacacttac gaaaagggaa
     8041 tatccgatcc agcaaccgct tgatttcatt ggctgccccc acatcgggat agggtccaaa
     8101 ataaagacct ccgtcctttt tgacctgacg agtgataatc aagcgtggat agcgctcatt
     8161 ggtgattttg atgaaaggat aggacttgtc atccttgagc atgatattgt acttgggctt
     8221 gttttccttg atcaggttga tttctaggag aagtgcctca atattagact ccgtaacaat
     8281 aaattcaaaa tccacaattt cagacaccag agcctctgtc ttggtatcat gacttccacg
     8341 aaaataggac cgtactcgat tacgcagatt tttagccttt cctacataga taatggtgcc
     8401 atttttatcc ttatgaatgt agcaaccagg gctggtcggc aagagctcta gttttgattt
     8461 aatcaagttg ttcatagttc cattatagca aaaaaagtag ggaaagatag taccctactc
     8521 actagtctca tatatttttc ggaggtttgc aacatcctct tcctggatac cataaaagga
     8581 acctgctggt tgcatgacag acttctcatc tgtatggtcc aagccaatcg catgacctaa
     8641 ctcatgttct gccgtatgga caaggcgttc ataggagtag ccatagtatg gattggacaa
     8701 ataataatga ttcaaccgca ccgttacgga caagaattgc cctgttaaga gattagtttg
     8761 actttccgcc tctcctgcca caggagtgcc tccgtcgttc atctccgtag ccgtaatatc
     8821 cgccttacta gactcagtca cgagttcaaa gttaaaagca cccgtttgat tccagttctg
     8881 gattgcttct aaataagcct cttgaaagcg tgaatccatc tgcggatcca ggtaaatacg
     8941 agcagaggcc tgtgcccacc ttccttcaga atgctggtga ctatctgtct ggcttaactt
     9001 aggcagttgc cctgttttct cccattggtc aatactttgt tgaccaattt ttactgaccg
     9061 ttctgcttgc tttagcgctc cttgaaaatc cccgttcaga taccagagaa gtccgaaagc
     9121 aagcacacat aagagcacaa ctatccaaac cagacgccaa aacaaacgcc acacaaaaga
     9181 aaagaaagcc cctatcaaac gaaaaagcca gcgcatgtct ctccaccttt ctagcaaata
     9241 agaattattt tactaaaaga agctaaaaga aatctaaata ctgacttttt catcttaacg
     9301 tcctactatt tttttgagta actggatagc tttgtatttt aaaggcgatg gatggtaacg
     9361 gaaagtaccc gctttgcgta caatatagcc attaaaattc tgtttaaaac gcaaaacacc
     9421 atcacttcca tcaaaaatcc cttgaatgcc taggaagttg tatttaggta ttccacgttt
     9481 tatgctttcc aacataacat atttttgaag cagtgcaggg gcatagaact tattaaactc
     9541 agtgtaggaa ccactaaaga gataagtcgt ttcctgaggc atataaacaa ataaactacc
     9601 agctaaaaca atatcttctt ctccatattt ttcaatcaag tctcgcgctt ctgcttttcg
     9661 aacttcaaac gtttcaaatt gactagaata ttctctcagt tgattttgtt ttttctcaga
     9721 atgaggattt ttactcaaat caagtcgcaa cttgtccaag ttttcttcta gtttattttg
     9781 ttcaccttgc aatttgctca tatagtccga aaaatttaag cttgctatga gaaactccgc
     9841 ttgttctcca aaagtatcat aaaaatgctc ataatattct aaacttttat cactatattc
     9901 tctacgttca gaggtttctt ttgttatatt cttaaaaatc gatagttctt cacgttttaa
     9961 ctttttcaac cgaatgccaa atgtttcagc ctttttcacc aagggtttac cctttttgct
    10021 aaaactttta agcaaactct tttcagttaa ttcagttaaa tctttatagt ataaccaatc
    10081 tggttctcca cctgggtaac ctgttgttaa gccatcaaat tgataaccta aatcagtcaa
    10141 accttgaata atactttttt tctcagcatc tattggatta ccttggctat caaaagtttg
    10201 ataagtttca taaggtttta caagcaactc taatacacca ttttgcttgg catattcttt
    10261 taactctgca taaaaaactg gaagagcatc ttgttgggta taaatcggcc ccgaattgag
    10321 ttccatatgc agaccaccca gcatgggcaa gctataaacc agagctgcaa cttgaatttc
    10381 tccttcttgt ttcaaagcaa gataaacaat tcgagcccct cttttttcta gcaaatcccc
    10441 catctggaca gattgcataa aggaacgaga agaaacctga tcagaataag tctgaaactc
    10501 ttctttcgtg agtgttgtta gtgccatata cttactttct atgttttttt cttaatgttt
    10561 tacggaaatc aagagcaagt cttaacatag gatagagagg atgagtgggc attgtaaatt
    10621 cacccaagta ttcttcaatc gttggattaa atttttcctt aaaatgataa agtccaccat
    10681 tgagagagtt ttcaacacca cctaaatttt gccagaccat acctcgctca aaggcatagc
    10741 gagccgtttc ataccaagtt aaaattggtg cattgtaacg tttaaaatca tcatccatac
    10801 cagcatatat attgacagag gtagtaccaa attccaaact caaagtagcc gctaaaggaa
    10861 ctctcgcttg acctacatct atatattcct gcaagaaggt caattcctct aacaaacgtt
    10921 ctttttcctt cttctgcgct tctacttttg aagttcgagt cgactcagta aaggtctctt
    10981 ccaaggctct atttttcgct aactgttctt ctaactcttg cgaacgttta gaaacatcca
    11041 aggtggccaa ggtgatatag gccttgtcct taaaattatc taacaatttt ttataatagg
    11101 cttcattcct caaatgaatc tcttttcgct tctcagtttt tttcatcaac tccgaaaatg
    11161 aatctaatag ttccagtcca ccatattgaa tctcaagccc tttgtttcgt gctgttcgaa
    11221 tagcctgttt tgttgacttg gaaagtttat cttcttcaaa attttccttg tatattttcg
    11281 cctgaatacg aggttgaatg gtgtctccca tttcctccgt ttttcctgac caccttactc
    11341 ccatttgttg caaactatca ataatagcca gattttcagg aaattctgtc ttttcctgat
    11401 tgattaaact ttgagatagg caaatacttg ggtcaaaagt cacaaaaatc gctctcttac
    11461 tgcgagcata ggacttaata gactgaatgg caaaattcaa gagttcttta tccccataat
    11521 ccaatatagg tcctcttggg atgtaaaaca ttttatagcc tagcggaaga gttctaatca
    11581 aaatactagc tgtcgccagt aatttttctt ccctgtaaac accaaacttc tcatgttgcc
    11641 aattagactt aacttcctcc caagcactac tttgtaatac attggctaat tcatgttctt
    11701 tgacaaactg atcatattct aatgtgggaa tgccaatttg ataacggtac atttcctact
    11761 ctctttcctc cagtatttta ttactattct actactttcg tttgaaaagt ctagtgaaaa
    11821 catattttat tttagttcta ctccccctat gctgaagttc aaactaagtc agtctctctt
    11881 ctaatttgaa atcaattggt agggttgtta aaaaaacttc caattgtttt tcccagtagt
    11941 accactcgtg agttccagca ctatggctat aggtcacatc aaaacctagt tttttgagat
    12001 ttttcactgc gagattattg gcttcgtaca agaaatcctg ttcgccacac cacgcccaaa
    12061 gtttggtctt tttatccgat tttttagcca gactttcaag agaataggga ctagttgtcc
    12121 agtctctaat ctctccaaaa acacctctcc agtaggctgg acttcccaga ttttgacttt
    12181 caggagaaaa gttttgaaag ctgagggcac ctgaaaaact agctgcatga gaaaaacgat
    12241 ttgtcgtaag agccagtttg aagcagccgt agcctcccat agaaagacca gcgataaagg
    12301 tcttttcacg cttgctagtc atattaggga agaagcgttt cagaacctgt ggcaattcct
    12361 ctgctagagc catgtagtag tcaaaaccat actgggtatc ggtgtaccaa ccattgctgg
    12421 tattgggcat aacaacgatg agattagttc ctcgaagcaa gcgttctaca ttggtccgct
    12481 taagccaact attatgattt ccagacatcc cgtgcaaaag gtacaagacg ggaatatctt
    12541 cacactctgg ttcttccact cgattggcat cagggtagag gacattcacc ccccactcca
    12601 tatccaatac ttgtgagtaa tactcgattt tcattactgc catgattttc tccttctatt
    12661 tttctataag aaaaagccga aactcgactt tctctctgtt tatttcaacg attattttgc
    12721 ttccatgact actggtaaaa tagctggacg acgcttggtt tggtcaaaga gatacttggt
    12781 caaattatct cgaaccttcc ctttaagatc tgcccagtca aagtcatctc cttgaagata
    12841 ctcttctacc gtttggttaa tcaattctga actttcacgg agaatatcgc gactcttctt
    12901 gagataaaca aatccgcgcg tatgaacacg agccctagcc acaattttct tctcacgacg
    12961 gttgactgta atagccacga tgaaaattcc atcctctgac aagaccttac ggtcacgaag
    13021 aacaacattt ccaacatcac caatggcatt cccatcaatc aagatatctc ctgctgaaac
    13081 cgatccagct ggaacaaagt ctccattctc gtaagccatg gtcgtcccct ttttaggaat
    13141 gaagatgcgt tctggcaaca tcccaactgc catggcagcc ttagcgtgag catccaactc
    13201 acgatactcc ccttggacag ggaagaggta cttaggttgc aaaagattga tcatcagctg
    13261 caaatcacgc acatttccgt gccctgatac atgtaaactt tgggtaatca atttgacaac
    13321 cccacctgcc tgataaatca tattttccac acgcgcaaca aaggcttctt tagcaataga
    13381 cggagccgta gcaatataga ccaggtcccc atccttgatt tctacataac gatggcgacc
    13441 aatcgacatc ttacgaagtc cattgatagg ttcacccata cgacctgtct caagaataat
    13501 caactcatgg tcttcaaagc gagacatatc tttaggctta atcaagagaa tttcgttggc
    13561 taaagacaac ttcttaagac gaatcgctgt gcggacgata ttttcaatat caaatcctgt
    13621 caagacgata cgtcgacctg ttttatccgc agcgtcaaaa atctgctgaa tacgagaaag
    13681 attactggaa acagctgcaa cgatgatacg accttcccag tcagcaatag tttgggtaat
    13741 ttcatcccta acttcacttt cactagccac ctgaatattg ctgtctgcat tggccgaatc
    13801 actgaggaga gccaggacgc cgtcacgacc aatctctgcc aaacgagcaa aatcagttgc
    13861 ataagattca ctagccgttt ggtcaaattt gaagtcacct gtataaacga tgcttccttc
    13921 cgatgtcttc aagacaattc ccagactctc tggaacggag taagtcgtag ggaagaagga
    13981 aaccactgtc ccaccaaaat caatctccgt attctcatca atgacatgga aatcattaaa
    14041 tttcttaacg gcatcatttc ctttgacaaa gagctttgcc aactcaatgg tcaactcaga
    14101 cccaaataca ggaactttag cctctgccaa gagataaggt agagcaccaa tggcatccgc
    14161 atgcccgtgg gtcaagaaaa ccccagcaat acggtcgcta ttttcaaaaa ggtaatccat
    14221 gtttggaatc accacatcga cccctaattg ttcattttca ggatatttta accctacatt
    14281 caaaacaaaa atggactctc caatttcagc aatgtacata ttttttccat tctcacgcac
    14341 accaccaagt gttgttaaac tgatattact catttttcct ccaaaatctt agtttatctt
    14401 gattataggg caactctacc ctcttattct aaaagttcta atactttcag ccgaatcttt
    14461 tcctaccatt ataccatttt tttgatgatt ttcaaaatga aggtctgttt tcaaaaaaga
    14521 gttgatttcc caactctttc ctaacttcta ctctttttcc atcaaaaaat cataaatttc
    14581 ttgcaccgta cccagcgcca tcatttcttg gtctttaacg gtttgtttga gattttggta
    14641 aatttgactt tctcctatct cccgctttgg cgcctcttta ttgactgtca tcacaccatc
    14701 ttttatcgtc acaaagccta gttcttcaaa tacttgaatc atcttgacca gcaagatttg
    14761 ttgaatatta agatatgcag ccaaatcttt cagcttgtag cgaatatcaa actctgggaa
    14821 ctggtaaata gtcttgtaca atttggcaaa ctgatctcta gtcccataac ctgtcagata
    14881 ataggccttg tcaatatcat ttttgaaata gacagcagag aaatgctgtt cctgaaaaat
    14941 ggtcttcagc tgagtaatat cctctggaat gttttttacg acaacagctt cactagccgc
    15001 aagatttggc agttctccag gaaaatccaa gactggaaca ccttctggca agactgcatt
    15061 ttttccacga atgttaaaaa gttgaacacc ttccactcgc gcatccatca tcatcaactg
    15121 gagggcagtt tggccgttcc attggttgac agacaattta accgctaact ctagattctt
    15181 ggtttgagaa aactctgtcg cccatctgcc ttgaccaaag gctaccactt caaaactcac
    15241 ctcacccttg gaaattttca gctttagatg ggcattacct gcccccatag tacgagcact
    15301 ttcgacctga aaattcttga tataaaaaat aggtttctga ttatccattc caaaaggagc
    15361 taaacgttca aaacttttga ccgtttccaa gctaagtgcc tccaaatcca actcttcatc
    15421 taggtttaac ttattcttgc caccagcatc tgcacctttt tcacgaacat aatcttccaa
    15481 aatctgagat aaatctgaga gttgctcaac ttccagcgtc atacccgctg cacctgcatg
    15541 acctccaaag gcgatgaaga ggtctcgata gggatccata gcttcaaaaa tatcgaccgc
    15601 ttccacacta cgagcactgc ccttggcacg accgtcttct atattaagaa caatgactgt
    15661 ctgtcccaat tcttccaata aacgaccagc cacgattcct agaaccccag gattccagcc
    15721 ttccttggcc aagacctgaa ccttcttctc aggatccacc atggtcttgg cttcttcata
    15781 gatagactga acgatttcct tgcgctcttc gtttttctgg tgaatcataa gggcaatctc
    15841 atgcgcttcc tcatcatcaa atccagtcaa caaatcaatg gcaggattgg gatcatccaa
    15901 gcgacccaag gcattcaaac gaggagcaat ctggaaacca accgtttctt ctgttacttc
    15961 gttagcagca atcccagcca tgtccagcat ttcttgcaga ccaatgcgct gggtatgacc
    16021 caacatttcc agaccatatt gaactaagat acgattttca tccgtcagac tcaccatatc
    16081 tgcaatagtt ccaatagcga ccaaatcaag caattccact tgcacttctt ctaacagggc
    16141 acaagccaac ttgaaagcaa ctccacaacc agccaaatat ttaaaaggat aatccgcatc
    16201 tggatgttca ggatggacaa tagcataagc atctggcagg gtttcaggta tggaatgatg
    16261 gtctgtcaca atgacatcta ctcccataga ctgagccaat gcaatagcct catgaccagc
    16321 aaccccattg tccaccgtca caatcaagga aattccttct tgctcgataa agtatttata
    16381 aacactagca ttagggccat agccatcggt aaaacgattt ggcaggtaaa ctcggcactc
    16441 cgcaccaagt tgttccaaac tttccttcac aatagaagcc gaagtcatgc catccgcatc
    16501 atagtctcca taaacgagaa tattttcccc ttcttcaata gcctgacgaa tccgctccac
    16561 tgccttgtcc atatcatgga gcagataagc atcatgtaag tcctccaagg aaggttctaa
    16621 aaacttcttc agactttctt ggtcctgaat ccctctctca aacaataacc gagccacctc
    16681 aggacccagt ccagccttct tggctatctt tgtaaaatcc gcatcttcta cctgcagggc
    16741 aaactgccat tcataagtag gtgttatcaa aaagacatcc actctttcta agaattctat
    16801 tgcttcatta taacatgatt tagacgtttt ctctatccag attgcttttt tataacattt
    16861 tatagtatat tgaaactaga atagtacacc tctacttcta aaatattgtt agaaatcgat
    16921 ttgattgtcc cgatcgattt ttcctgttct tatatcacta tagtgaattt tttcagatat
    16981 gatttgacaa gaacattctt ttatcgtaga atcatgttat aaaatctaac ataaaggagt
    17041 tctctcatgg ctttagtaga atttaaaaac gtcgaaaaat attacggaga ctaccacgca
    17101 ctccgcaaca tcaatctccg ttttgaaaaa ggacaagttg ttgtcctgct tggaccttct
    17161 ggctctggga agtccactct tatccgtacg atcaatggtt tagaggctgt tgacaaagga
    17221 agtctcctag tcaatgggca ccaagttgct ggtgccagcc agaaagattt ggtacctctt
    17281 cgcaaggaag tcggcatggt ttttcaacat tttaaccttt atccacacaa aacagtgtta
    17341 gaaaacgtga cacttgcacc cattaaagtt ctaggaattg ataaaaaaga agctgaaaaa
    17401 accgccaaaa aatatctgga atttgtaaat atgtgggaca agaaagattc ctatcccgcc
    17461 atgctatctg gtggacaaaa acagcggatc gccatcgctc gtggtcttgc tatgcatccg
    17521 gaactcctcc tctttgatga accaacatct gctcttgatc ctgagactat cggagatgtt
    17581 ctagcagtta tgcagaaact ggcgcgtgat gggatgaaca tgatcatcgt tacccacgaa
    17641 atgggctttg ctcgagaggt tgcggaccgc attatcttta tggccgacgg agaagtttta
    17701 gtagatacga cagatgtcga taactttttt gacaatccaa gcgaacctcg tgcccaacaa
    17761 ttcctcagca aaattatcaa ccacgaaagt gacaaagtca aataaggagg cgcctatgaa
    17821 aaaaaattct ttttatcagc attattgatt agccttttcg gccttgctgc tgccaaacca
    17881 gtccaggctg atactagtat cgcagacatt caaaaaagag gcgaactggt tgtcggtgtc
    17941 aaacaagacg ttcccaattt tggttacaaa gatcccaaga ccggtactta ttctggtatc
    18001 gaaaccgact tggccaagat ggtagctgat gaactcaagg tcaagattcg ctatgtgccg
    18061 gttacagcac aaacccgcgg cccccttcta gacaatgaac aggtcgatat ggatatcgcg
    18121 acctttacca tcacggacga acgcaaaaaa ctctacaact ttaccagtcc ctactacaca
    18181 gacgcttctg gatttttggt caataaatct gccaaaatca aaaagattga ggacctaaac
    18241 ggcaaaacca tcggagtcgc ccaaggctcc atcacccaac gcctgattac tgaactgggt
    18301 aaaaagaaag gtctgaagtt taaattcgtc gaacttggtt cctacccaga attgattact
    18361 tccctgcacg ctcatcgtat cgatgccttt tccgttgacc gctctattct atctggctac
    18421 actagtaaac ggacagcact actagatgat agtttcaagc catctgacta cagtattgtt
    18481 accaagaaat caaatacaga gctcaacgac tatcttgata acttggttac taaatggagc
    18541 aaggatggta gtttgcagaa actttatgac cgttacaagc tcaaaccatc tagtcatacc
    18601 gcagattaag gaggataccc tatgacagat ttatcatctt ggacagccta ttttcaggat
    18661 tttggacaat ttttcaatgg tttcctcttt actcttgccc tagcgattgg atcctttatc
    18721 ctcgccatgg tcttaggaat cttctttggt gccatgtcaa ccagtaaacg tccaatttta
    18781 cgcattttag ctcgcatctt tgttgaattt taccaaaata ctcccctctt ggtgcagttt
    18841 gttattgttt tttatggcct acctcttatc agtgaccata tcatcatgat tccaatttat
    18901 tggacagccg ttctctgcgt gggactctat cacggcgctt atatcgctga ggttattcgt
    18961 tcagggattc agtctattcc tagtggtcag atggaggccg ccttgtcgca aggttttacc
    19021 tatatcagtg ccctgcgctt gattatcttg cctcaggcct tccgcatcat tctccttcca
    19081 ttgaccaacc aaattgttaa cctcatcaag aacacctcta ctgtagctat catctctgga
    19141 gtagacttga tgtttgtgac taagtcttgg tcggctctca acggaaacta tatcccaggc
    19201 tttttaggtg ctgctcttct ctactttgcc ctatgcttcc ctgttgccca gtttggtcgc
    19261 aagatggagc aagccaacaa aaaagcctat tcactttagg aggttactat ggaatctatt
    19321 ttagaagttt taaccccaga taacctagtc tttatcttta aaggatttgg cttgaccctc
    19381 tatatttctc tgattgccat catcctctct actatcatcg gtacggtgct agctgtcatg
    19441 agaaatggca aaaatcctgt cttgcgaatc atctccagta tttatatcga gtttgtgcgc
    19501 aacgttccca accttctctg gatttttact atctttttgg tgttcaaaat gaagtccaca
    19561 ccagcaggta ttacagcctt tactctcttt acatcagcag ccttggctga gattattcga
    19621 ggcggtctca atgccgtaga caagggacaa tacgaagcag gaatgtcaca aggcttcacc
    19681 tcagcccaaa tcctctacta catcattctc ccacaagcca tccgcaaaat gctaccagcc
    19741 atcatttctc agtttgttac cgtgattaag gataccagtc tcctctactc tgttatcgcc
    19801 ctacaagaac tctttggagc cagccaaatt ctcatgggcc gttatttcga accagagcag
    19861 gtcttcagtc tttacatcct gattgccctc atctacttca gctttaacct agcaatttct
    19921 agcctgtctc atatgctagc caaacgttgg caacaagctg cagaataata ctcttcgaaa
    19981 atctcttcaa accacgtcag cttcaccttg ccgtatatat gttactgact tcgtcagttc
    20041 tatccacaac ctcaaaacgg tgttttgagc agcctgcggc tagcttccta gtttgctctt
    20101 tgattttcat tgagtataaa cagccactct ccagttcaat tggagagttt tttgatgata
    20161 gtagatattt atagacctca atttgacacc atacattttc tatgataaaa tgtaacaaat
    20221 ttatttacaa caaatcgaaa tctaaatgaa atggaatttt ctatgaaatc agtcaaagga
    20281 ctactcttta tcatagctag ttttatcttg actcttttga cttggatgaa cacttctccc
    20341 caattcatga ttccaggact agctttaaca agcctatctc tgacttttat cctagccact
    20401 cgtctcccac tactagaaag ctggtttcac ggtttggaga aggtctacac cgtccacaaa
    20461 ttcacagcct ttctctcaat catcctacta atctttcata actttagtat gggcggtttg
    20521 tggggctctc gcttagctgc tcagtttggt aatcttgcca tctatatctt tgccagcatc
    20581 atccttgtcg cctatttagg caaatacatc caatacgaag cttggcgatg gattcaccgc
    20641 ctggtttacc tagcctatat tttaggactc tttcacatct acatgataat gggcaatcgt
    20701 ctccttacat ttaatcttct aagttttctt gttggtagct atgccctttt aggcttacta
    20761 gctggttttt atatcatttt tctatatcaa aagatttcct tcccctatct agggaaaatt
    20821 acccatctca aacgcttaaa tcacgatact agagaaattc aaatccatct tagcagacct
    20881 ttcaactatc aatcaggaca atttgccttt ctaaagattt tccaagaagg ctttgaaagt
    20941 gctccgcatc ccttttctat ctcaggaggt catggtcaaa ctctttactt tactgttaaa
    21001 aattcaggcg accataccaa taatatctat gataatcttc aagccggcaa caaagtaacc
    21061 ctagacagag cttacggaca catgatcata gaagaaggac gagaaaatca ggtttggatt
    21121 gctggaggta ttgggatcac ccccttcatc tcttacatcc gtgaacatcc tattttagat
    21181 aaacaggttc acttctacta tagcttccgt ggagatgaaa atgcagtcta cctagattta
    21241 ctccgtaact atgctcagaa aaatcctaat tttgaactcc atctaatcga cagtacgaaa
    21301 gacggctatc ttaattttga acaaaaagaa gtgcccgaac atgcaaccgt ctatatgtgt
    21361 ggtcctattt ctatgatgaa ggcacttgcc aaacagatta agaaacaaaa tccaaaaaca
    21421 gagcttattt acgaaggatt caagttcaaa taagtaatca tactctcctg gaatttccca
    21481 ggagagtttt ttatagccaa atgaaataag acaggaacga tggaattttg gcattcaaat
    21541 caattgataa gaatgtttta tagtggagtg aaataggata cgaacaaatt gattaggaaa
    21601 atcaaatgaa tttatagaaa tcttttagca gttatgttgt cctattctag tttcaaaacg
    21661 ctatagaagc agcattgtgc tagtctagat tcagtttact atactaaaac gagtagcttg
    21721 aaatcaaaaa acccaccctc acaggcaggt tttatctgta ttattcagct agattatgct
    21781 ttaccttctg aaccgaatac gtcgatacgt tcttcaaccg atgcttggat agcttttaca
    21841 ccgtcagcca agaatttacg tgggtcgaag agttttttct tgtcgtattc tgcttcgttt
    21901 gcttcgtagt cacgagcaaa tttacgagtt gcgttagcga atgcgatttg gcattctgtg
    21961 ttaacgttaa ctttggcaac accaagtttg atagctgctt ggatttgctc atcaggaata
    22021 cctgatccac cgtgcaatac gattgggaat cctggaagag cttctgtcaa tttttgcaag
    22081 tggtcaaggt caagaccttc ccagtttact gggtaagggc cgtggatgtt accgatacca
    22141 gctgccaaga agtcaatacc agtttcaacc attgctttag cgtcttcgat tggagccaat
    22201 tcacctttac cgatgattcc gtcttcttca ccaccgatag taccaacttc agcttctact
    22261 gagatacctt tagcgtgtgc tttttcaaca acttctttag ccaatttaag gttttcttca
    22321 actggaaggt gtgaaccgtc aaacatgatt gaagtataac caacttcgat acactcaagt
    22381 gcatcgtcgt agtgaccgtg gtcaaggtgg atagctactg gtacagtgat acccattgat
    22441 tcaacaaggt tagcgatcaa gttgcgagca actttgtaac cacccatgta tttagcagca
    22501 cccattgaag tttggatcaa aactggagct tttttagctt ctgctgcgcg caagatagct
    22561 tgagtccact caaggttgtt tgtgttaaat ccaccaactg cataaccgtt gtcacgggct
    22621 gcttggacaa atttttctgc tgaaacgatt gccattttat caggcctcct gtatattttt
    22681 atgggtcatc ccatttacat tgttcatttt atcacttttt gccaaaaaaa tctagttttt
    22741 cccgcagttt cgattgattt tcttctaact ccatctatgt aaaccctttc tctccctagt
    22801 cttgggcgac ttttggaaaa gctataaaga aggttaaacg attctcctcc atctcgaaac
    22861 gataagctaa tttttcatgt tctaatagac tcttaaccac aaagagcccc ataccagacc
    22921 ccttgacctt gcgactagca ttgtcagaaa aagactgggc tagtttttct tgttcctctg
    22981 agctacagct attttcgata aaaagttctc cttctctttc tccaattcga actaagccac
    23041 ctggaacaga gtgcttaatg gcattgctga tgagattaga aagaatcaac ttcataactg
    23101 atgggtttag ataagcctgc tgatgggtca aactattgtc tatctggagc tctctttcct
    23161 tggctagcaa ggcataatct ttgaccagat tttgcgtcat ctggaggagg tcaattgttt
    23221 ccctatcatc tcgcaattcc tgcacagaag agagggaaag tatctgcaga acatggtgat
    23281 tgagttcatc cacaatcccc aaggcaactc ccagatactg gtctctatcc ttataacgac
    23341 cgatattctc tctcatattt tcgattagga ttttcaaact agccagcggt gttttcaatt
    23401 catgagaagc tcctcgtagg aattcgacct tcatcttctc cagctggaga atggcttcat
    23461 tcttttcatg caagtccgca ataacagtca agagatgctg gtagaggcta ttgatttgtt
    23521 ccttgagatt acctatctca tccttagaat ccacgcgcaa tcgcacttgg gaatccaggt
    23581 ccatcatccg acgggtcacc cgcttgattt ccaaaatcgg tgcaacaata gtccgagcgt
    23641 agatgtaggc caccaagagg gaaatcagaa aggaggccag caaggtatag ggaagaaact
    23701 ggagactgat ttgctccgct tccttttgta aatccatgga agctagaaac tggagaatca
    23761 tagtaccacc gtcttgcgtt ttcacctcgc gctcctcaat aaagagagag gttgtctggc
    23821 ggtctgtgtc cagaggaaga ctgtccttga cttctaactt gtcctcggtc atctcacctt
    23881 tgacggtccc cttgatatca ctagtctggg aatacaagtc taacacttgc tcgatactct
    23941 gcctatcttt cccttctagg gactgggcaa tggctgttgc cttttgacca atggtttcct
    24001 gacgatgact cagataagtc gaaggaaaaa gaaaataaat agctaaatga aggcagataa
    24061 ccagaacact aaatatcgag aaggtataga taaatatctt tgtaaataaa cctgttcgtt
    24121 tcattttcgc tccaatttat aaccaacatt gcgcacagtg aggatacaat ccaagtctag
    24181 ctttttccgc aattccttga tataaacatc aataacacgg tcaaagggaa cctcatctgt
    24241 cgctttccag acggcatcga taatctgaga tcgagtcaag gcccggcctt catttttcac
    24301 tagatagtcc agaatttcca actctttggc attgataggc acttcttgac ctgcgaggct
    24361 tgcactgtag ctttcaaagt ccaccttggt atccttgtaa gaaaagattc gtcctgtatc
    24421 gtagtagcgc ttgaaaatcg cgtccaccct cacttttaaa agggagaggg agaaaggttt
    24481 ttccagatag ccatctgcca aagaggcaaa ggcactcatc ttgtattcct catcctgaaa
    24541 agctgtcaac atcaagacag gaacctgact ggttttacga atctcagcta ggacttctaa
    24601 gccgttgagc ttgggcatct ggatatccag taaaaccagg gccacctcat agctagaaaa
    24661 ttgctccaga gcttcctgac cgtccgctgc ctcaatagtt tcatagccac aatccgtcaa
    24721 ataatcactg accccctcac ggatcatctc ttcatcttct acaattaaaa ttttcatact
    24781 ttaactgctc tctatttttt atttttctta gaataaatac ctactctatt ttctattata
    24841 gtctcttgct ggccttttgt ctgtaagcaa ctgatcacta gataaaacgt tgtgaaattc
    24901 ctttctcata aattccataa ctttagtata ttatatttaa gcactaaagt acaaagaaag
    24961 caactgaaag caatgatttt caccactgct ttcagattta ttttgaattg ttaaatagct
    25021 attcctatcc actattcttg aatagaaaca caagatgcaa tctttattcc agactcattt
    25081 tttcaaattt attcaccatc cagcaagagc tcttttggtt gttttctaag gagattgctt
    25141 gaagcaagcg ccataacgag aaccactaga accaaggcaa ggacaaaaat gatgataaag
    25201 tctgatgtct gaatagaaat gtctaggctc gacaaggtct tgctaaagcc atctacttct
    25261 gcaccaccac caaggttaga ggcttgagcc gccttactag cctgtttggc aacacctgaa
    25321 gtcacattgg caaggacagt gtttccaatt gcacgggcag tgtaattagc taggaagtaa
    25381 gcagaaacta gagcagggat agcaatcaag atagattcgg tgatgaattg acccaagata
    25441 cttgcctgct tgaggccgat agagaggaga attcccactt ccttgcgacg ggcgttgatc
    25501 caaaggctga gcaagagggc aaggaggaga actgagaagc tcaagctacc ccagaagagg
    25561 aggttggcca tcttgtacat accagagata gattgctcaa gagctgggta gttagaggag
    25621 ctcttgacga gtgtgtagct cttccagttg ataccactga tgccattcaa ctctttcata
    25681 acatcatcca agttcttgtc tgctgttaca aagaaggttg cgtccccata aatggctgtg
    25741 tcttctgtgt atccataaag ttttgcagca gtgtgaatgt ctgtaatagc tgtgttttcg
    25801 taaagttctt gtgagtaggt tactgctgac ttattatgac catcaaagag tcccttgatt
    25861 gtcacttcaa ctgtttcctt ggctcctttt tcattatctg catcgtagat attagagtcc
    25921 agtttaacct tgtcccctac tttccagccg tgtttggctg ccaagtcctt gtgcaagagg
    25981 attttatcct tgtcgtcgtt ggttaagtgc tctccttcga ctagtttata agaaccagag
    26041 acaaacttgt cttctttaga ggagtcattg acacctgtaa tcatcaagct acttccaaaa
    26101 cgtttggcac gatcagcagt gagattcttc ttggtttctg gcgtttcaat caggtcatat
    26161 ccagtcaaat ctccgatagc gttgatacgt ttgacataag actcaatggc cttgttttcg
    26221 gtgatttttt tgatgtcttc acccttgata ttcccagcac cgcgaggcgt tccttggttg
    26281 acgcgacgat tgatttgcat ggagaagcta ttggtgatat ttttaaaggt ctcctgagaa
    26341 gccttggcag tagctccctt gattgacaag ccgaccaaac tcaagctcgc catgaggaga
    26401 ataatcagga agatgacaat cgatttgaaa aacttccttg taacataggc aaatgcgttg
    26461 tgtaacatag attccctttc tagattttgt tttaatcatt ctattaaagt aagctcaaat
    26521 tatttactag tattgcgcgt ttcagtcagt ttcttatcct ttaattcaag tgtaatatct
    26581 gacgcttgtg ccacttcttt actgtgagtt acgacaatca cacatttacc tgttttctgg
    26641 gcaagtgatt tgagtagttc gacaatatct ccagcagttt taggatccag atttcctgtt
    26701 ggctcatcag ctagaataac tggagcttct gagaccaaac tgcgagcaat ggcaacacgt
    26761 tgctgttgac cacctgataa ctggagaaca ttccgcttga tctgactttc atccaaacca
    26821 agctcaagaa gtgtatcctt gcttgccttt ttgttgacca attggatatt ttccagcgga
    26881 gaaagataat ctatcaagtt ataattttga aagaccaggg aaatatggtg catgcgatgg
    26941 taagaatagc ccttcttacg aatatcctct ccttgaaaaa ggatagaacc ttcaacagga
    27001 ctatctagac cagcaagtag ggacaagagt gtggattttc ctgctcctga ctccccaata
    27061 atactgtaaa attttccggg ttcaaaatta taattgatct gatataggac tgcttcagca
    27121 gtattcttat aacggtaggt aacatcttgt aattgtaata aagtcatgat ttctccttct
    27181 taactaatag atgataaaat ttctttcggt gattttctaa ataagaatag gaaacaaagg
    27241 gctacagata agcaactaag cagaactaga aaaacatagg attctgcaaa agataagatg
    27301 ctagttgata aactgcttgc tttggctagt gtatcttgta agcttgcctg atctccactt
    27361 gctagtagag tttggagtag gtaagttgtg attgcgtttc ctgcaacaaa tgctggaagc
    27421 aaagctccaa gagataccaa aactacctct aaacagaatt gtaggaagat cgagctcttg
    27481 ccttttccaa gtgcaagtaa aatccccact tcatagaccc gttctctcaa ccagagagac
    27541 aaaaccagaa ttaaggctcc agctcctgct atcaacatcc cataaaggaa gatggtcagg
    27601 aaggtttgga aagttgcaac tgagtctttg atttgttcaa aagccttgtt ttccttttcg
    27661 acttggtagc cttgattttc caaggccaag ttttctacct gcttcatgag tccgtccatt
    27721 tccttaggat tttctacata gaagcgtgct gcactgactt gagcttcact attgcccaaa
    27781 agggtttggc tactttcata gtctgtaaag acttgatttt cactgaagtc agaagacaag
    27841 cctgtgaatt tctcttgttt tttaccagaa aagatgccaa taatctcaaa ctctactgtt
    27901 tgtccttttc cagattcaga ctgaccagca tccaagccaa tcttgtcatg aagtgaaaga
    27961 ccgttcttct tagccaattc ttcgtggata aggattttct tggaatcccc tttttgaagg
    28021 tgtcgccctt cttttagatt gaaagccgaa ctggtaaagg ttacatcctt ggatgaatcc
    28081 tcaagagccg ttaagctaac caagttattg tctgcagctg ataaatcatc acgctccacg
    28141 ctctgctcgc cagtcactgc ttccttgtct tttagttttg cgaccgtctc aagttcagga
    28201 gagacatttt ccagcccctt aatcttgctt acagatgcta ggtctgacaa cttgaatgtc
    28261 tgaccattct ctatcttctt aatagaaaaa gatgtattga gtgatttata aagattgctt
    28321 tctactgttt tgttggactt catcagagtc aaacaggctg aaattccggc caataagacc
    28381 aataaaatca gaaataaaat aaaacttctc agtcgctttc tgctgacata agcccaagat
    28441 ctttggattg gattcatttg tcacctccat atttgtaaga ctattataaa acccaaatat
    28501 gaaatgttta tgaaatacga aaaaaaaa
//
LOCUS       DAVHBD010000028        28135 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000028 DAVHBD010000000
VERSION     DAVHBD010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28135
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.028"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="VVK04_001304"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="VVK04_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU3989960.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1319..2023
                     /locus_tag="VVK04_001305"
     CDS             1319..2023
                     /locus_tag="VVK04_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3989961.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2016..3365
                     /gene="vicK"
                     /locus_tag="VVK04_001306"
     CDS             2016..3365
                     /gene="vicK"
                     /locus_tag="VVK04_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU3989962.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3367..4176
                     /locus_tag="VVK04_001307"
     CDS             3367..4176
                     /locus_tag="VVK04_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU3989963.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDIATPLTEI"
     gene            4267..4509
                     /locus_tag="VVK04_001308"
     CDS             4267..4509
                     /locus_tag="VVK04_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU3989964.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4511..4765
                     /locus_tag="VVK04_001309"
     CDS             4511..4765
                     /locus_tag="VVK04_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU3989965.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4812..5585
                     /locus_tag="VVK04_001310"
     CDS             4812..5585
                     /locus_tag="VVK04_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU3989966.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5848..6834)
                     /locus_tag="VVK04_001311"
     CDS             complement(5848..6834)
                     /locus_tag="VVK04_001311"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU3989967.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7028..9496
                     /gene="gyrA"
                     /locus_tag="VVK04_001312"
     CDS             7028..9496
                     /gene="gyrA"
                     /locus_tag="VVK04_001312"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU3989968.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9496..10239
                     /gene="srtA"
                     /locus_tag="VVK04_001313"
     CDS             9496..10239
                     /gene="srtA"
                     /locus_tag="VVK04_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU3989969.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            10483..11280
                     /locus_tag="VVK04_001314"
     CDS             10483..11280
                     /locus_tag="VVK04_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU3989970.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            11428..11550
                     /locus_tag="VVK04_001315"
     CDS             11428..11550
                     /locus_tag="VVK04_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEU3989971.1"
                     /translation="MTCDFKFETLQLHAGQVVTPATESRAVPIYQTTSFVFDDT"
     gene            11572..12687
                     /locus_tag="VVK04_001316"
     CDS             11572..12687
                     /locus_tag="VVK04_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEU3989972.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDIDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQVPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGSSCHNLSYIRDVGAATFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPNQIRLSIGLENVEDLIEDLRLALEKI"
     gene            12783..14057
                     /locus_tag="VVK04_001317"
     CDS             12783..14057
                     /locus_tag="VVK04_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU3989973.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            14069..17253
                     /locus_tag="VVK04_001318"
                     /pseudo
     CDS             14069..17253
                     /locus_tag="VVK04_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17354..18232
                     /gene="truB"
                     /locus_tag="VVK04_001319"
     CDS             17354..18232
                     /gene="truB"
                     /locus_tag="VVK04_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU3989974.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEDATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            18473..18775
                     /locus_tag="VVK04_001320"
     CDS             18473..18775
                     /locus_tag="VVK04_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU3989975.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            18883..19521
                     /gene="udk"
                     /locus_tag="VVK04_001321"
     CDS             18883..19521
                     /gene="udk"
                     /locus_tag="VVK04_001321"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU3989976.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            19649..20989
                     /locus_tag="VVK04_001322"
     CDS             19649..20989
                     /locus_tag="VVK04_001322"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU3989977.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            20967..21179
                     /locus_tag="VVK04_001323"
     CDS             20967..21179
                     /locus_tag="VVK04_001323"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU3989978.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            21176..22051
                     /locus_tag="VVK04_001324"
     CDS             21176..22051
                     /locus_tag="VVK04_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU3989979.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            22044..22859
                     /locus_tag="VVK04_001325"
     CDS             22044..22859
                     /locus_tag="VVK04_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU3989980.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            22852..23283
                     /locus_tag="VVK04_001326"
     CDS             22852..23283
                     /locus_tag="VVK04_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU3989981.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            23290..24957
                     /gene="recN"
                     /locus_tag="VVK04_001327"
     CDS             23290..24957
                     /gene="recN"
                     /locus_tag="VVK04_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU3989982.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            24959..25687
                     /locus_tag="VVK04_001328"
     CDS             24959..25687
                     /locus_tag="VVK04_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU3989983.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            25766..27589
                     /gene="lepA"
                     /locus_tag="VVK04_001329"
     CDS             25766..27589
                     /gene="lepA"
                     /locus_tag="VVK04_001329"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU3989984.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(27793..27873)
                     /locus_tag="VVK04_001330"
                     /pseudo
     CDS             complement(27793..27873)
                     /locus_tag="VVK04_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         8823 a         4719 c         6277 g         8316 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat tcctggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccgg atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctttggcccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttg gtataatagt agagaaaaag gtgaacatat
     1321 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
     1381 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
     1441 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
     1501 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
     1561 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
     1621 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
     1681 tatgccagta gatggtcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
     1741 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
     1801 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
     1861 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgta cagttgatgt
     1921 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
     1981 gacgcgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
     2041 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
     2101 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
     2161 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
     2221 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
     2281 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
     2341 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
     2401 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
     2461 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
     2521 atggcgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
     2581 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
     2641 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
     2701 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
     2761 aggtttctct tgatgagacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
     2821 cacgtattga taatgctacc agtcacctag atgtggaact gattaacttc actgctttta
     2881 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg
     2941 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
     3001 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
     3061 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
     3121 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
     3181 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatta
     3241 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
     3301 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
     3361 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
     3421 tctttttatc tggaaacctc aaaaaagaag cttttagtag atgcaggctt gtctggcaag
     3481 aaaattacca gtctgctagc tgaaattaac cgtaagccag aagacctgga tgccatcttg
     3541 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
     3601 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
     3661 aaggtggatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
     3721 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
     3781 atgaaggatg ataagagttt tgtcctcttg acagatacag gttatgtcag tgaccgtatg
     3841 gcgggcattg tcgaaaatgc ggatggttat cttatcgagg ccaaccatga tgtagagatt
     3901 ttgcgatcag gttcttacgc ttggcgcctc aaacaacgaa tcctatctga ccttggtcac
     3961 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
     4021 atttaccttg ggcatttatc taaggaaaac aatatcaagg aactggctca tatgaccatg
     4081 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
     4141 tcaccagata tcgcaacacc attgacagag atatagaaag aacgctgaga aggtgttctt
     4201 tttatattga ctggacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
     4261 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
     4321 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
     4381 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
     4441 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
     4501 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
     4561 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagatcc
     4621 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
     4681 taattatcga gttatcgtac aaattgtaga tgatgaatta gttgttgcta ctctagaagt
     4741 tggtcatcgg agagatattt attaaattaa agctgagtaa taacagtata gaaagtaagg
     4801 agagtaaaaa tttgaagaaa aaatggtttt ttgcagatta ttatgacaca acaattattt
     4861 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
     4921 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
     4981 gttggcgctt ttttacgact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
     5041 tattggctat tctcccttta aatgctattt ttacagtgtt tcgattaggg cgtatctttc
     5101 gtttagctaa actaacaaaa ttactgaaac tgactcgttt acttagaata attggactta
     5161 caggtaaatt agaaagaaaa attagtagat tcttacggac aaatggcctg atttatatct
     5221 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     5281 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggatatgggg
     5341 atattgttcc tgcttccatt tttgggaaat ggctagcagt tttactgatg cttgtcggta
     5401 ttggaacaat agggatgtta acaagtgctt tgacgaactt ttttgtaaag gataatccag
     5461 atgaacagat aaaacttgat aaactccaag atgaattatc tagtcagaga atattactag
     5521 agaaacaatc taaaaagata gaagaactac ataaaatgat acaagatttg attgaaaaaa
     5581 cataataaaa ataaagatga gaaaaagttt gaactgagga gaaatcaagt aagttttgac
     5641 acaatagaac gcatattatc aggtataaaa acttgatact atgcgtttta ttgtgggaag
     5701 atgtataatg gattgaaata agatatgaac aaatcgatta ggaatttaaa gcattttata
     5761 acaacgtttt agagtaacgg ggtactattt catataatac aggaaaaaac aactccctga
     5821 tgattcaagg agttgtctat agttaaatta gtttttagaa gcttcttgga attctgggtt
     5881 tttccatgct tcgtcaatga tagcttgcaa ttctttagca gatgcttgca ttttttgagt
     5941 ttctgcgtcg ttcaatggga tatttactgg acgaacaata ccatgtgcac caacaacagc
     6001 tggttgaccg ataaagacgt tctcaactcc gtattgacct tcttggaata ctgaaagtgg
     6061 aagtactgca ttttcatcgt caaggattgc tttagtgata cgagcaaggg ctactgcgat
     6121 accgtagtat gttgcacctt ttttgttgat gattgtgtag gctgcatcac gaacaccttc
     6181 gaacaattca atcaattcag cttcttgaac attttgagta tctttaagga attcttcaag
     6241 gtttacacca gcgatgttag cgtgtgacca aacagcgaac tcagagtcac cgtgttcacc
     6301 catgatgtag gcgtgaactg aacgagcatc tacgtccaat ttttcagcaa gtgcttgacg
     6361 gaaacgagct gagtcaagtg aagtacctga accgataacg cgttctttag ggaaaccaga
     6421 gaatttccaa gttgagtaag tcaaaacgtc aactgggtta gcagcaacaa ggaagatacc
     6481 tttgaaacct gattcaacaa cttgagttac gattgatttg ttgatagcaa ggtttttacc
     6541 tacaaggtca agacgagttt cacctggttt ttgaggcgca cctgcagtga tcacaacaag
     6601 gtcagcgtct gcacagtcag agtattgagc tgcatagatt tttttaggtg aagtgaaggc
     6661 aagggcgtga ctaaggtcaa gcgcatcacc aacagctttt tcatgcaatt gtggaatttc
     6721 gataattcca agctcttgtg caattccttg gttaacaagt gcaaaagcgt aagatgaacc
     6781 tacagcacca tcaccgacaa ggataacttt tttgtgttgt ttagttgaag tcattgtttt
     6841 aaacatctcc ttaattttat taggggattt tccctagata acttcattct atcactttta
     6901 aaaaactttg tcacgaatat gccttatagt tctcgatgta aacgttttag tggtttagag
     6961 gctgaaatag atgggaattt atggtataat gttgttactt actaattgtg aaatgaggca
     7021 tttattaatg caggataaaa atttagtgaa tgtcaatctg acaaaggaga tgaaggcaag
     7081 ttttatcgac tacgccatga gtgttatcgt agcgcgagct cttcctgatg ttcgagatgg
     7141 cttaaaacct gttcaccgtc gcattcttta cggaatgaat gaattgggtg tgaccccaga
     7201 caaaccccat aaaaaatctg ctcgtattac aggggatgtc atgggtaaat atcacccaca
     7261 cggggattcc tctatttatg aagccatggt ccgtatggct caatggtgga gctaccgtta
     7321 catgcttgta gatggtcatg ggaattttgg ttccatggat ggagatagtg ctgccgctca
     7381 acgttatacc gaggcacgta tgagcaagat tgctctggaa atgcttcgtg atatcaacaa
     7441 aaatacagtt gatttcgttg ataactatga tgccaatgaa cgggaaccct tggtcttgcc
     7501 agcgcgtttt ccaaaccttt tggttaatgg agcaactggt atcgcggttg ggatggcaac
     7561 caatattcca cctcataatc tgggtgaaac cattgatgca gtgaagttgg tcatggataa
     7621 tcctgaagtg actaccaagg acttgatgga agtcttgcct ggaccagatt ttccaactgg
     7681 tgctcttgtc atggggaaat caggtatcca taaggcttat gaaacaggta aaggttcgat
     7741 tgtcctacgt tctcgtacag agattgaaac gactaagact ggtcgtgagc gcatcgttgt
     7801 aacagaattt ccttacatgg tcaataaaac caaggtgcat gagcatattg ttcgcttggt
     7861 tcaggaaaaa cgcattgagg gtatcacagc agtacgtgat gagtcaaacc gtgaaggtgt
     7921 tcgatttgtt attgaagtca agcgcgacgc ctcagccaat gttattctca ataacctctt
     7981 caaaatgacc caaatgcaaa ccaattttgg tttcaatatg ctcgctatcc aaaatggtat
     8041 accgaaaatt ttgtctcttc gtcagatttt ggatgcttat atcgagcacc aaaaagaagt
     8101 ggttgttcgt cgtacacgtt ttgataagga aaaagcggaa gcgcgcgctc atatcttaga
     8161 aggtctcttg attgcgctag accatatcga cgaagtgatt cgtatcatcc gtgctagtga
     8221 aacggatgcg gaagctcaag ctgagttgat gagcaagttt aagctttctg aacgtcaaag
     8281 tcaagctatc cttgatatgc gtcttcgtcg tttgacaggt ttggaacgcg ataagattca
     8341 atctgagtat gatgacctct tggctctgat tgcggattta gcagatattc ttgctaagcc
     8401 tgaacgtgtt tctcaaatta tcaaagacga attggatgaa gttaaacgta aattttctga
     8461 taagcgccgt acagagttga tgattggaca ggtcttgagt ctcgaggatg aggacttgat
     8521 tgaagaatcg gatgtcttga ttaccctttc taacagaggc tacattaagc gtttggatca
     8581 ggacgagttc actgctcaaa aacgtggggg tcgtggtgtc caaggaacgg gagtgaaaga
     8641 tgatgacttt gttcgtgagt tagtgtcaac tagcacccat gatcatctgc tcttcttcac
     8701 aaacaaggga cgtgtctatc gtcttaaagg ttatgaaatt cctgagtatg gtcggactgc
     8761 caaagggcta ccagtagtca atctcttgaa attggatgaa gacgaaagta ttcagacggt
     8821 tatcaatgtt gagtctgatc gcagtgatga tgcttatctc ttctttacaa cccgtcacgg
     8881 tattgtgaag agaactagtg ttaaggagtt tgccaatatt cgtcaaaatg gtctcaaagc
     8941 gctgaattta aaggatgaag atgagttaat caatgtcttg ttggcagaag gagatatgga
     9001 tattatcatt ggtaccaagt ttggttatgc agttcgcttt aatcaatcag ccgttcgtgg
     9061 tatgagccgt atcgccactg gtgtgaaagg tgttaacctt cgtgaaggag acacagttgt
     9121 tggtgccagc ttgattactg atcaagatga agttcttatt atcacagaaa aaggatatgg
     9181 taagcgtaca gtcgctactg aatacccaac aaaaggtcgt ggtggtaagg gaatgcagac
     9241 agctaaaatt accgaaaaaa atggcttgct ggccggtctt atgactgttc aaggggatga
     9301 ggatttgatg attatcactg atacaggtgt catgattcga accaatcttg ccaatatttc
     9361 acaaacagga cgtgcaacta tgggagttaa agtaatgcgc ctggatcaag atgctcagat
     9421 agtgactttc acaacggttg cggtggcaga aaaagaagaa gttgggacag aaaacgaaac
     9481 agaaggtgaa gcataatgtc tcaaaaaaat aataaaaaga aaaacaagcg aaaaaatctg
     9541 ctgacaaata tcctagcagg atttctgata ttactgtcac tggctttgat ttttaatact
     9601 caaattcgaa atattttcat agtctggaat accaataagt atcaagttag ccaggtatca
     9661 aaagaaaaat tagaagaaaa tcaggataca gaaggcaatt ttgactttga ttctgtcaaa
     9721 gctatctctt cggaagctgt tctaacttct caatgggatg ctcaaaaatt accagttatt
     9781 gggggaattg caattcctga attggaaatg aatttgccga tttttaaagg acttgataat
     9841 gttaatctct tctacggagc tggtacaatg aaacgcgagc aagtaatggg agaaggaaat
     9901 tatagtctag ctagtcacca tatctttggt gttgataatg ctaataaaat gttattttct
     9961 cctttagata atgctaaaaa tggcatgaag atttatctaa ccgataaaaa taaagtttat
    10021 acttatgaaa tacgtgaagt caaacgtgtg acaccagatc gtgttgatga agttgatgat
    10081 agagatgggg tcaatgaaat cacattagta acctgtgaag accttgctgc tacagaacgt
    10141 attattgtca aaggtgattt gaaagaaaca aaagattatt cacaaacatc tgatgaaatc
    10201 ctaacagctt tcaatcaacc atataaacaa ttttattaat acaaatcagt gaaatcatgg
    10261 atttcactga ttttttaaga ttttcataaa aatatagtaa aatgaaataa gaataggacg
    10321 aatcgttcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt
    10381 ctagtttcaa tctactataa acttttatga aatacagaaa acgcttccta aaacctaaag
    10441 tttgtgatat aattatcaag aaaaaagatt taggagttta ttatggtttc ttcagaattt
    10501 atctcaaaga ttgaatttgc ttgcaataag aaagaaagtc tttatagtca aagcaaattt
    10561 aagtatgcga ttcgttcgat gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt
    10621 gcagttgggg ctgacttgat taataaaatt gcaccaggta gtggacgctt cctctttcca
    10681 ttcgtttttg cttggggctt ggcctacatt gtttttttga atgccgagtt ggtcacttca
    10741 aacatgatgt tcttgactgc tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct
    10801 gagattttac tatactgtac cttgttcaac cttatcggag ccttgatagc agggtggggc
    10861 tttgctcatt cggcagccta tgcgaatctg acacacgata gtttcatctc aggtgttgtt
    10921 gagatgaagt taggccgctc aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt
    10981 ttcgtaaata ttgcgattct gtcatttatt ttggtcaaag atggtggtgc caaactttgg
    11041 cttgtgttgt cagctattta catgtttgta ttcttaacaa acgagcacat tgcggcgaac
    11101 tttgcttctt tcgcgattgt gaaattcagt gttgctgcgg attcaattgc caacttcggt
    11161 gttggaaata tgcttcgcca ctggggtgtg actttcatcg gaaactttat cggaggaggc
    11221 ctcttgatgg gtcttccata tgccttcctc aataaaaacg aagatactta tgtagattaa
    11281 gaaaatgagc acgattgagt cgtgcttttt tcattttcaa aataaggtaa tagctatttc
    11341 ttatatcaaa atatagaaaa ctgatatttg taaactataa ctcaaggtgc tacaatatcc
    11401 ttaataaaat gatatggagg tcaccttatg acttgtgatt ttaaatttga aactctacaa
    11461 ctacatgctg gtcaagttgt gactccagct actgagtctc gtgcagtgcc gatttatcaa
    11521 acaacatctt ttgtttttga tgacacgtag gaaggtgctg atctgtttgc cttgaggaaa
    11581 ccagggaaca tttatactcg tatcaccaat cctacaacag ctgcccttga aggtggtgtt
    11641 gaagcgctag caacagcatc aggtatgact gcagtgactt atacgatttt ggcgcttgcc
    11701 catgctggtg accatgtagt ggctgcttcg actatttacg gtggaacctt caatcttttg
    11761 aaagaacccc ttcctcgtta tggtatcaca acaacctttg tcgatattga taatttggag
    11821 gaagtagaag cagctatcaa agacaatacc aagcttgtct tgattgaaac cttgggtaac
    11881 tccttgatta atattccaga cctggaaaaa ctggcagaga ttgctcataa acatcaagtc
    11941 ccacttgtgt cagacaatac ttttgcaaca ccttatttga ttaacgtctt ctctcatggc
    12001 gttgacattg ccattcactc tgcgactaag tttatcggtg ggcatggtac aactattgga
    12061 ggaataattg tcgatagtgg tcgttttgac tggacggctt cagggaaatt ccctcaattt
    12121 gttgacgagg gttcaagctg ccacaatttg agctatattc gtgatgtggg tgcagcaacc
    12181 tttattatag ctgttcgagt tcaattgctt cgtgatacag gtgcagcctt gtcaccattc
    12241 aatgctttcc tcttgctaca aagacttgaa actctttcac ttcgtgtgga acgccatgta
    12301 caaaatgctg agacaattgt tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat
    12361 tatccaaaac ttgcagatag tccttatcat gccttggctg agaaatactt gccaaaaggt
    12421 gtcggttcaa tctttacctt ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt
    12481 gataatttag aaatcttttc tgaccttgca aacgcggcag atgctaaatc gcttgttgtc
    12541 catccagcaa caaccactca cggtcaattg tcagaaaaag acctagaagc agcaggtgtc
    12601 acaccaaacc aaattcgtct gtcaatcggt cttgaaaatg tagaagattt gattgaagac
    12661 ttacgcttgg ccttggaaaa aatttaaagt aaaagaagat aaacagtggg ttttgactca
    12721 ctgtttttga ttttccctca ggcatgatat aatggttaca gaagtctaga aagaggaatg
    12781 taatgaacga aatcaaatgt cccaactgtg gggaagtctt tacagtaaat gaaagccagt
    12841 atgctgaact tttgtcccaa gtgagaacgg cagagtttga taaggaacta cacgatagga
    12901 tgaggcagga actggccttg gctgagcaaa aggctatgaa tgagcaacag actaaactgg
    12961 ctcagaagga tcaagaaatt gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa
    13021 aagaattggc caagaaagaa gttgaacaga caagccatca ggccttattg gctaaggaca
    13081 aggaagtaca ggccttggaa aaccagttgg cgaccttgcg tttggagcat gaaaatcaat
    13141 tgcaaaagac cctttctgac ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac
    13201 tgcaagaaaa ggaaaatgag ttgtctttgg cttctgttaa gcaaaactac gaagcccagc
    13261 tcaaagcagc cagtgaacaa gtcgagtttt ataagaattt taaggctcaa caatctacaa
    13321 aagcgattgg ggaaagccta gaacagtatg cagagagtga gtttaacaag gttcgtagtt
    13381 tcgcctttcc aaatgcttac tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag
    13441 gggactttat cttccgtgag tgtgatgaaa atggagttga aatcatttct atcatgtttg
    13501 agatgaaaaa cgaagcggac ggaacagaga agaagcacaa gaatgcagat ttttacaagg
    13561 aattggacaa ggaccgtcgg gagaagaact gtgagtatgc cgttttggtg accatgcttg
    13621 aggctgataa tgactacttt aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa
    13681 tgtatgttgt tcgtcctcaa ttctttatcc aattgattgg tctcttacgt aatgcggcgc
    13741 taaattccct aaaatacaag caggagttgg ccttggttcg cgagcaaaat attgacatta
    13801 cgcattttga ggaagatttg gatgccttta agctagcttt tgctaagaac tataattcag
    13861 cttcgactaa ctttggaaaa gctattgatg aaatcgacaa ggccatcaaa cgcatggaag
    13921 aggttaagaa attcctgact acatctgaaa accaactccg tctagctaac aacaaattgg
    13981 aagatgtctc tgttaaaaaa ttgacccgga aaaatccaac aatgaaagcg aagttcgaag
    14041 cactgaaggg ggagtgagga aataagttat ggaagatgat cttaattatg aaaatttgat
    14101 ggatgatgta accgaggcta taaaaaagtt taacttagta atttttattg gcgcaggagt
    14161 ttcaattgct caaggttatc ctaattggaa caattatatt gaacatctta ttaagtattg
    14221 gcaaggacaa gttttatcgg taagtggtga aaaaaggctt ggaagagaac atcacgtagt
    14281 ttttgattta attagcaaat ctagtattag taataaacgt aaagtggatc ttgtaaacta
    14341 tgaattaaaa aaagtttttg gtgaagattt tgaaaagcga cgactagatt ttgaaaaagg
    14401 atattttaaa aatctattac catattcaat agttaatcaa acagtagaat ctttagcaag
    14461 tttgaatgca atatttatta cttctaacta cgactatgaa attgaaaatc atattaaacg
    14521 tttaaagaat gctgtagtta ctattaatga tctcaatgaa ttcactaaga acaagaatgg
    14581 gaaactacaa tttggtgatg ttctacatat ccatggaaca ccagattgtg atgtaaagta
    14641 ttttgtaagt tcatccgcag attattcaaa aacctattta aaaaataggg aaaattttga
    14701 aaatttagta acatggttta aagagacaaa acctactgtt ttatttgttg gagcaggtct
    14761 tgaagaagat gaaattttat ctttactttg taaagatagt aagaactatg ccttgatgaa
    14821 gtcagagaac acaggtaatc agagagttga tgaacattat agaggtgttg ttgaaggatt
    14881 ttttagctca gaaaatcata ctcagattat ttggtacgga gatgaatttg agaaactacc
    14941 tctttttgta aaaaaattag ttgctgatat taatgaaaaa ttgggcacac atgattttta
    15001 taatcagtgg aacaatcttt tgaatccttc tataaatcaa gaagagtata ataaaaatct
    15061 agatagtatt tctaatgatt ttaagtatct aagctctgtt ttagataagg ttattgaaaa
    15121 tgataataat caactagatc agctaatgtt aaatgctctg cttcggagtg aaactctaac
    15181 agtaattaaa aaaattttgt ccttgcattt tggaggttta ttgttaagaa tattgaaaag
    15241 ttaagtgata atgagtggga tgtgatttat aaaataattt atgaaggctc tcaaaattac
    15301 tttatagatg atgtattctt tgtctataat tatgcgatag ataataaaat ttctagtttt
    15361 acaaataata ataagcttaa tgaactgaga gaaattatat ccaaagatgg atatatcgtt
    15421 aattctaact ttaataaaga taaaactctt ttgggttact ggctagtaag tgcttttgaa
    15481 cagcaaaatc gtgatttata tataaaggaa gatagtgaag tagaagttaa cttaaattac
    15541 gaatgtgtta acaaattaat gtccatacta aataatccag aatttttaag ttataattac
    15601 tactctatag agcatcaatt aaaagagtat gatgttgtta aatttcttta tgagcttgta
    15661 aagtccaaaa aattatttat tgaagaggaa aagtttttag aaagtgattc tgaagactta
    15721 ataagtacta tattaattca aaaattgctt gttcaattgg ataatgaaat taatttggat
    15781 ttagaattta tcaagaggtt aattgataaa attgattttt caaatattca ctttggagag
    15841 gaattaaaca cttttatcaa agaacataga agtattatta gagaaaaaaa tattgaaata
    15901 ccaaaaaaac cttatagaaa ttggatatct tcactagaag gaggttttgt ttcacaattt
    15961 tcatatttaa ctcaagaaaa tcttgtagag tacgatgaat ctagagtatt agagatatta
    16021 gtcaacgccg aaaaggaaca aagaggttct tcatttttgg aagaaaagac gataaatgaa
    16081 acggaaaatt tctttattac tgttttaaaa gaatcaaatg aaatatctaa aaaagtttct
    16141 gatttattga aaaatcatat agatgactta tatccaaaat ataagagatt atatgtaaaa
    16201 attatcagtt ttcctgaaat agaagaaaat ttgagaaaga ttgttagaga aaaatattta
    16261 aaaagattta acaaagaaag ttttgattct aacgatcgga aattctttga atatcatata
    16321 aaacaacaaa atacggatat agatattttt gaaaaattac ttagtatcaa tgtgaatgaa
    16381 ctctcaacac caaaaggtga taataaacaa ttagatatac ttcattttat aaatagtgaa
    16441 atgggatcat attttcaatg tttaatatca ttatttataa atcattcaag ttatagagat
    16501 gtaattattc aaataataaa ttcagtaaca gataccgatt atagggagtt tgctcaaggt
    16561 attttattaa atgaatacaa tccaaacaga atcaatgtaa cttacaacac ctttttagga
    16621 tttgcgtatt atcattctac aattactatc gaagctgcgg atgttttcac agatgtagta
    16681 agggatattc taaacaaaaa aattgaggac aatcaaattc ttaataaagt ttatctagtt
    16741 gctttagaga gggtagatcc aactattgaa tcattttctt tatcaaagaa taactatagt
    16801 caaatgataa acatcatttt tacaggagac tatgaattta gatattctaa agaatggttg
    16861 ggagcattat tcaaatttga ctcaagtgca aattatttgg tgacaatttt ttatttatta
    16921 tataatgaaa atcttaaaaa aaatagattt gctttgttta tagaggaatt gagtgattac
    16981 ttaacaactt ataaccagaa attatcttta cgagggatga attataaatt gaatcatgaa
    17041 gaacttaaca attttgattt gttgaaaaaa atgtttctga aattaatgga gaccgataaa
    17101 atagagaatg atatttttta tttagatggc atcaaaagta tactcccatt attatcttta
    17161 gatgacagac gaaatgtatt acaacatatt caaaaacaga acaattgtcc tcctccagag
    17221 attgaggaat tacaaagaat tatagttaat taaaatttgt aaaaaagaga ataaaaggta
    17281 gacgacgcct cagtaaaaat tggcccggaa aaaagcgaag ttcgaagcac tgaaggggga
    17341 gtagaaagca aaaatgaacg gtattatcaa cttaaaaaaa gaagcaggaa tgacctcgca
    17401 tgatgcggtt tttaaactgc gtaagatttt gggaaccaag aaaattggtc atggtggaac
    17461 cttggatccg gatgtggtgg gtgttttgcc gattgcggtt ggcaaggcga cacgcatggt
    17521 cgagtttatg caggacgagg gtaagatcta tgagggggaa atcactctgg gctattccac
    17581 gacgactgag gatgctagtg gggaagtggt cgcagaaacc cctgttttgt ctcccttgga
    17641 tgaaaagctt gttgatgaag cgattgctag cttgactggg cctattactc agattccccc
    17701 tatgtattcg gcagttaagg ttaatggtcg caagctctat gagtatgcgc gtgctggtca
    17761 ggaagtggag cgtccagaac gtcaggtgac catttatcaa tttgagcgaa caagtccgat
    17821 ttcttatgat ggccaacttg cccgattcac ttttcgtgta aaatgcagta aagggactta
    17881 catccgtact ttgtcagttg atttgggtga aaagcttggt tatgcggctc atatgtccca
    17941 tttgactcgt actagtgctg ctggcttaca attagaagat gctcttacct tggaggaaat
    18001 tgctgaaaaa gtagaggctg ggcaattaga ttttctccat cctttagaga ttgggacagg
    18061 tgaccttgtc aaagttttcc taactccaga agatgctaca gaagttcgct ttggtcgttt
    18121 tattgagcta gaccaaacgg acaaagaact ggctgccttt gaagatgata aattgttagc
    18181 cattctagaa aaacggggca atctctataa gccaaggaag gtttttagct agatcgttta
    18241 ggaataaaaa tcgggtgata gataacaatt gcttgataaa accccatact aatagtagaa
    18301 tggttttggg aattataata ttccaattgt tgcgagttgt agatactcaa ataatctata
    18361 tagaaattta gaggtgtgaa atgaagcaac ttaaaattct ttcagataaa tatttagagt
    18421 ccattacagg ttctggtggg aacttaggcc caggatttgg tgtgataatt ccatgatgcg
    18481 aaatgagttt cgagaaaggg tggagcaact tcttcaacaa aaagaaataa atgaaaatag
    18541 tgagttgagt cacctgtttc gtcttgctat acaaaattta gacagaaatg aaaaatacca
    18601 aacggtcatg gccaatttga gtcaagggtt gtcactttac ctcatgacgc atcattacca
    18661 ggcacctaag tctgtcattg attttggttt atggattgcc aaagctccta gccaggaaag
    18721 agggagactg gctttcttgc agatgcttgc tcaaacccta cagggctttc gttaaaactg
    18781 tcgaacatca gagggaagac tctggtgttt tttgctgatg agactataaa ttttgtaaaa
    18841 aatgtgatag aatagacgac ggataaaata acggaggata gcatgcaaaa tagaccaatc
    18901 attattggag tgacaggtgg ttctggtggt ggtaaaacca gtgtttcaag agccatttta
    18961 tcgcattttc ctgatgaaaa gatttccatg attgagcatg attcatacta caaggatcag
    19021 tctcatttga cctttgaaga gcgtgtcaaa accaactatg accatccttt tgcctttgat
    19081 acagacttga tgatcgagca gattaaggaa ttgttggcag ggcgtccggt ggacatcccg
    19141 acctacgact atacagagca tacacggagt agcaagacct atcgtcagga gcctcaagat
    19201 gtctttatcg ttgagggcat tttggtcttg gaggacaagc gtctgcgcga tttgatggat
    19261 atcaagattt ttgtggatac ggatgacgat gtgcgcatta ttcgtcgtat caagcgtgat
    19321 atggaggagc gtggccgtag ccttgatagc gttattaacc agtacttagg tgtggtcaaa
    19381 ccaatgtacc accagtttat cgagtcaact aagcgttatg ctgatatcgt cattcctgaa
    19441 ggggttagca ataccgtggc tatcgacctg ttgacgacca agattgcaaa gattttggaa
    19501 gaagctcgaa acagcaaata atcacatgtg gaggccttgc ctcctttttc tatttttccc
    19561 tcataatggt acataaatgg agatttttag gcatattttt ggtataataa tacccatgaa
    19621 agagcaagta aatgaatagt aggtggagat ggaaaagtat ttatcggtaa caactttgac
    19681 caagtatctg aaaatgaaat tcgataaaga cccatacttg gaacgggtct atttaactgg
    19741 tcaagtttcc aactttcgta aacgacctac tcaccaatat ttctccctaa aggatgacca
    19801 tgcagttatt caagcgacca tctggtctgg gatttatcag aaattagggt ttgacctgga
    19861 agaaggaatg aagatcaatg tgattgggcg tgtacaggtt tatgaaccaa gtggtagcta
    19921 ctccatcatc attgaaaaag ctgagcctga tggggttggg gcgcttgcga ttcagtttga
    19981 acaacttaag aaaaaattga cagaagaagg cctgtttcaa gaacgcttca agcaagctct
    20041 gccccaattt tctaagagaa ttggggtagt aaccagccgt agtggagccg ttattcgaga
    20101 tattatcacg accgtcagca ggcgattccc aggtgttgac atccttcttt atccgaccaa
    20161 ggttcaaggt gaaggggctg cggaggaaat tgctagaaat attgcgcgtg ctaatcaacg
    20221 ggatgatttg gatttgctca ttattggtcg tggaggtggt tctattgagg atctctgggc
    20281 ctttaacgaa gaaattgtgg tacgagctat ttttgaatct cgtttgccag ttatctctag
    20341 tgtggggcat gagacggatg tgaccttggc agattttgtg gcagatcgac gcgctgcaac
    20401 gccaacagcg gcggctgaac tggcaacacc tgtgaccaag ttggatgtat tagctcattt
    20461 gcaaaatcag gaaaaacgga tggcaacggc agtccgaaat gttctatcta agaaacaaga
    20521 ggctttgaaa aaatgcagtc agtctgttat ctttagacaa cctgagcgct tgtatgacgg
    20581 ttatttgcaa cgcttggacc aactgcaact gcgtttgaaa caaagtttgc gaactcggat
    20641 ttctgataac aaacaattag ttcaagcaag aactcatcaa ttagtacaat tatcacctgt
    20701 taccaaaatc caacgctatc aagaccgttt aggacagttg gacaagctct taggtagcca
    20761 aatggcgtta gtttatgacg ccaaggttgc tgaggccaag cgactttcgg aagctttgct
    20821 catgttggat actagccgaa tcgtggcgcg tggttatgct attgtcaaaa aagaagagtc
    20881 cattgtagat tcggttgaga gtttgaagaa aaaagaccaa gtaacgcttt tgatgcgaga
    20941 tggtcaagta gaattagagg ttaaagatgt caaaacaaaa gaaatttgag gaaaatctag
    21001 cagaactgga aaccattgtc caaagtttgg aaaatggtga aattgctctg gaagatgcga
    21061 ttactgcctt tcaaaagggc atggtcttgt caaaagagct ccaagctacg ctggacaagg
    21121 ctgaaaagac cttggtcaag gtcatgcaag aagacggaac agaaagtgat tttgaatgaa
    21181 aaagcaagaa aaattagctc ttgtcgagtc ggctttggaa gatttttatg gagaccagca
    21241 gtttgcctct agtttacggg agtctgttct ctattctatt catgctggtg gcaagcgtat
    21301 tcggcctttt ctcttgttag aagttctgga atccttgcag gttgccatca aacctgctca
    21361 cgcgcaggta gctactgcct tggagatgat tcatacaggg agcttgattc acgatgacct
    21421 tcctgctatg gatgatgacg attatcgaag agggcggtta accaatcaca agaaattcgg
    21481 tgaagctatg gccattttgg ctggagatgc cttattctta gacccatatg ccttgattgc
    21541 gcaggcagat ttgccaagtc agatcaaggt ggacttgatt gccaacttat cccttgcttc
    21601 aggtagtctg ggtatggtgg cagggcaagt tttggatatg gagggcgaac accagcactt
    21661 gtctctggaa gaacttcaga ctattcatgc caataagact gggaagttac tagcctatcc
    21721 cttccaagcg gcagctatta tagctgaatt gtcacctgaa atgcaggtga agctgaaaac
    21781 tgtgggtgaa ttgattggac ttgcttttca agtcagagat gatgtactgg atgtgacagc
    21841 tagttttgag gaaatcggca agacacctca aaaggatctg caggcagaaa aatcaaccta
    21901 tcctgccttg ttgggcttgg aagagtccat tgccttttgt aaccaaaccc tggatcaagc
    21961 taatgaaaaa ttagaagaaa ttgcccagca gcttcccttt gaaacagaat cgattgtaag
    22021 tgtagtagaa agtttgagaa tcaatggcta aggaaagagt ggatgtacta gcttataaac
    22081 aggggttgtt tgaaacgaga gagcaggcca agcgaggtgt gatggctggt ctagtcgtag
    22141 cagtccttaa tggagaacgg tttgacaagc caggagagaa aattccagat gacaccgaat
    22201 taaaactcaa gggggagaaa ctcaagtatg tcagccgtgg tggtttgaaa ctggaaaagg
    22261 ccttgcaggt ctttgatttg tcggtggatg gcgcgactac gattgatatc ggggcctcta
    22321 ctggaggttt taccgatgtc atgctacaga atagtgccaa gttggtcttt gcagtcgatg
    22381 ttggtaccaa tcagttggct tggaaattac gccaagaccc acgagttgtc agcatggagc
    22441 agttcaattt tcgctatgct gaaaagactg atttcgagca ggagccgagc tttgccagta
    22501 ttgatgtgag tttcatttcc cttagtctga ttttgccagc cttgcaccgt gtcttggctg
    22561 atcaaggtca ggtggtagca cttgtcaaac ctcagtttga ggcaggacgt gagcagattg
    22621 ggaaaaatgg aattattcga gatgctaaga ttcatcagaa tgtccttgaa tctgtaacag
    22681 ctatggcagt agaggcaggt ttttcagtcc ttggcttgga cttttctccc atccaaggtg
    22741 gacatggaaa tattgaattt ttagcgtatt tgaaaaaaga aaagtcagca agcaatcaga
    22801 ttcttgctga gattaaagaa gcagtagaga gggcgcatag tcaatttaaa aatgaataaa
    22861 aaagaaagac ttgaaaaaat tagaagattg gtgacagatt atcaaatcgg cacgcaagaa
    22921 gaaattgtag aacatttgaa agaagcaggt atcactgcca ctcaggcgac ggtatcccga
    22981 gatatcaaag agttaggtat tgtcaaaatt cctttgagag acaacaccta tgtctacgaa
    23041 ttgccaaaat caatcgtaaa aagtctgcaa ctggctgaag acaatatcga atcggctgaa
    23101 ttgatggata agatgatcaa tctccaagtt attccaggaa atacggcttt tgtaaaagct
    23161 cagttaatcg agacttttgc agacaagatt tttagctgtt tgactgatga tagctcgatt
    23221 ttagtcattg ccagaagtgg aagtctagca gaggaaatct ttgaacaagt aaaaaattgg
    23281 taggtctata tgttacttga aatttcgata aaaaactttg ccattattga ggctatttcc
    23341 ctcaattttg aaaaggggat gactgtcctg actggtgaaa cgggtgcagg gaagtcgatt
    23401 atcattgatg ccatgaatat gatgttggga gctcgtgcga cgacagatgt tattcgtcat
    23461 ggtgcaccaa aggcagagat tgaggggctt ttctcagttg agaatagtcg tcttttacag
    23521 gaaatttttg atgagcaagg tttagaatta ggtgatgaaa ttatcatccg tcgggaaatc
    23581 ttgcaaaatg gtcgtagtat cagccgtgta aatggtcaga tggttaatct gtctgttttg
    23641 cgaactattg ggcaacatct tgtagatatt catggtcagc atgaccatga ggagttaatg
    23701 cgtccccaac tgcatatcca gatgttggat gaatttggtg atgccgcttt ttgggacttg
    23761 aaagaaacct atcaaacgag ttttgatgcc tatcggaaaa tgcgcaagca ggttctggaa
    23821 gtcaagaaaa accaacagga acacaaggca cgtatcgaaa tgttggaatt tcaaatggca
    23881 gagattgagg cagcaaactt gcaggctgga gaagacttgg ctctcaatca agagcgagat
    23941 aaactcctca accacaaaaa tattgcggat acactgacca atgcctacag tatgttggac
    24001 aatgaagatt tttcaagtct ggccaatgtt cgttcagcca tgaatgacat ggaaagtgtc
    24061 gaagagtatg accctgaata ccgtgaaatt tcaagctctc tgtctgagac ctactatgtt
    24121 ttagaagaca ttagcaaacg tttggaagct atcattgagg accttgattt tgatggcaat
    24181 cgcctcatgc aggttgagaa tcgtttggac ctccttcata ctattactcg taagtatggt
    24241 gggactgttg atgatgtttt gctttatttt gccaagatta cggaagaata caatctcttg
    24301 acaggcaata atctttcgtc tgaggacatg gaagcagagc ttaagaagtt ggaagtcaat
    24361 cttgtcaatt tggcaggtca acttgcttct gctcgtcata atttggctca gcaactcgaa
    24421 gctgagatta aacaagaact gcaagatctt tatatggaaa aagcccagtt tcaggttcgt
    24481 tttagtaagg gaaaattcag tcgtgaggga aatgaaatgg ttgagtttta tatttcaacc
    24541 aaccctggag aagactttaa acccttggtt aaggttgctt ctggagggga attatctcgt
    24601 ctcatgttag ccattaagtc tgccttttca cgtaaagaag gcaagactag cattgtcttt
    24661 gatgaagtgg atacgggagt ttcaggtcgt gttgctcaag ctattgctca gaaaattcat
    24721 aaaattggtc agcatggtca ggttttggct atctcccatt tgccacaagt aattgcgatt
    24781 gcagattatc aattctttat tgagaagatt agtaatgacc attcaacggt ttcgactgtt
    24841 cgtctcttga cggtcgaaga gcgagtggag gaagttgcca agatgttggc aggtgatgat
    24901 gtgacagaag cagccctgac gcaagccaga gaattgttga gaaacaggga gaaataagat
    24961 gacagattat tatgtaattg gagatgttca cggaaaagct gggatgctgg aagaccttct
    25021 taaaacctgg gatggtcaga cccagttgct ctttctaggt gatttgattg acagaggtga
    25081 ggatagtcac cgtgttcttg aaatggtcaa ggacttggtg gacaatcaag gggctatctg
    25141 tttgtccgga aaccacgagt atatgttttt gacttggcta gatgacccag aagaaagtta
    25201 tgaccattat cgtcgcaatg gtggagatac aaccattaac tctatcctag gtcgtccctt
    25261 ggatgcacca gttgatggag tagaagatgc caagcgggtt gccgctgaag cgtcagactt
    25321 ggtcgaattc attcgtcaaa tgccatttgt agtagagaca gacaagtata tatttgttca
    25381 cgcaggtatt gatttgactt tggacgactg gcatgaaaca acagattata aaaaagtatg
    25441 gcttagaaaa ccattccacg gagctgaaaa tcatactgga aaaaccattg tcttcggtca
    25501 tacaccggtc tatggtttgt tacagcaaga acgcggtaca tctgagcttt ggactacaga
    25561 agatggcaag attggaatgg atggaggagc tgtttatggt ggtgtccttc acgggattgt
    25621 ctttacagac caaggaatga cagaacacca ctttatcgaa aatgacggct ttgtcgctga
    25681 agattagtac tcctagcagg gtatggtctt gtcaaaatat caaaaacaat ttataataaa
    25741 tagataccct gaaaggaaga gaatcatgaa cttagaagaa ttgaaaaaac gacaggagaa
    25801 gatccgtaac ttctctatta tcgcccatat tgaccacgga aaatcaactc tagcagaccg
    25861 cattttggaa aaaacagaga cggtttcaag tcgtgaaatg caggcccagc ttttggatag
    25921 catggatcta gagcgggaac gtggaattac tattaagttg aatgccatcg agttgaatta
    25981 cactgcaaaa gatggagaaa cttatatttt ccacttgatt gacacaccag ggcacgttga
    26041 ctttacctat gaagtttcac gttcgctagc tgcctgtgag ggtgctattt tggtggtcga
    26101 tgcggctcaa ggaattgagg ctcaaactct tgccaacgtt tatctggctt tggataatga
    26161 tttggaaatc atgcctatca ttaataaaat tgacctgccg gctgcagatc cggagcgcgt
    26221 gcgtacagag attgaagatg tgattggttt ggatgccagt gaagcagttt tggcttctgc
    26281 caaggctggg attgggattg aagaaatcct cgagcaaatt gtagaaaaag taccagcacc
    26341 aacgggtgat gtgacggcgc cacttaaggc cttgattttc gactctgttt acgatgctta
    26401 ccgtggggtt atcctccaag tgcgtgtcat ggacggagtg gtcaaacctg gtgataagat
    26461 tcagctcatg agcaatagta agacctttga tgtggccgaa gtcggtattt ttacaccaaa
    26521 agcggttggt cgtgatttcc ttgcgactgg tgatgttggt tacattgcgg cgtctatcaa
    26581 gacggttcag gatactcgtg tgggtgatac cgttaccttg gcaaccaatc ctgcggcaga
    26641 accattacat ggttataagc agatgaatcc tatggtcttt gcgggtctct acccaatcga
    26701 atcaaacaag tacaatgacc tgcgtgaagc gcttgaaaaa ttgcaactga atgatgctag
    26761 tcttcagttt gaaccagaaa catctcaggc acttggattt ggttttcgtt gtggatttct
    26821 tggacttctc catatggatg ttatccagga acgtttagag cgtgagttca atattgacct
    26881 catcatgaca gctccgtctg ttatttacaa agttaatttg accgacggtg agtctatgga
    26941 tgtgtctaac ccatctgagt ttccagaccc aactaagatt gcgaccattg aagagcctta
    27001 tgtcaaggcg caaatcatgg taccacagga gttcgtcgga gcagtaatgg agctagctca
    27061 gcgtaagcgt ggggactttg tgactatgga ctatattgat gataaccgtg tcaatgttat
    27121 ctatcaaatt cctcttgctg aaattgtctt tgacttcttt gataaactta agtcttcaac
    27181 acgtggttat gcaagctttg actacgaatt gtcagaatat cgcccatcta agctggtgaa
    27241 aatggatatc cttctcaatg gagataaggt ggatgctctc agctttatcg ttcacaagga
    27301 ctttgcctac gaacgtggga aactcatcgt tgataaactc aagaaaatca tccctcgcca
    27361 acaatttgaa gttccaatcc aagcggctat tggacacaag attgtcgctc gtactgatat
    27421 caaggccctt cgtaagaacg tacttgctaa atgttatggt ggtgacgttt ctcgtaagcg
    27481 taaactcctt gaaaaacaaa aagctggtaa gaaacgcatg aaatccatcg gatcagttga
    27541 agttccgcaa gaagccttcc tcagcgtctt gagtatggat gaagaataag ttatcagaaa
    27601 tgcctttcct tgttcacagg aaatttatat aagaatcaat agtaaagcag gcttagatgg
    27661 tctgcttttt tagtttttat actcttcgaa aatctcttca aaccacgtca tcgtcgcctt
    27721 accgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac catgttttga
    27781 gctgacttcg tcagtttcat ctacaacctc aaaactgtgt tttgagtaac ctgcggctag
    27841 cttcctagtt tgctctttga ttttcattga gtattagaac agaaaaatgc ttggagtatt
    27901 tgtttgtgtg tttattttta tataacaaac tataaacaaa acaaaaatat aaaaaaagag
    27961 acaaaaaaga atagaaagta attaacaacg atttcatata gtgttatact tatagcataa
    28021 agttaatgga aagaagggaa aaccttatgg tattagatta tttctttgac aaaaaccttg
    28081 tgttttgctt agaagcggat aatcaagaat aactttttga ttaggtagca agctt
//
LOCUS       DAVHBD010000029        26203 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000029 DAVHBD010000000
VERSION     DAVHBD010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.029"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            91..588
                     /locus_tag="VVK04_001331"
     CDS             91..588
                     /locus_tag="VVK04_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU3989985.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFHETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            588..2243
                     /gene="dnaX"
                     /locus_tag="VVK04_001332"
     CDS             588..2243
                     /gene="dnaX"
                     /locus_tag="VVK04_001332"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU3989986.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2271..2465
                     /locus_tag="VVK04_001333"
     CDS             2271..2465
                     /locus_tag="VVK04_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU3989987.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2615..3385
                     /gene="sufC"
                     /locus_tag="VVK04_001334"
     CDS             2615..3385
                     /gene="sufC"
                     /locus_tag="VVK04_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU3989988.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3413..4675
                     /gene="sufD"
                     /locus_tag="VVK04_001335"
     CDS             3413..4675
                     /gene="sufD"
                     /locus_tag="VVK04_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU3989989.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPNFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4686..5912
                     /locus_tag="VVK04_001336"
     CDS             4686..5912
                     /locus_tag="VVK04_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU3989990.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLNAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5899..6339
                     /locus_tag="VVK04_001337"
     CDS             5899..6339
                     /locus_tag="VVK04_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU3989991.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6393..7805
                     /gene="sufB"
                     /locus_tag="VVK04_001338"
     CDS             6393..7805
                     /gene="sufB"
                     /locus_tag="VVK04_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU3989992.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8004..9245)
                     /locus_tag="VVK04_001339"
     CDS             complement(8004..9245)
                     /locus_tag="VVK04_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU3989993.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9348..10457
                     /locus_tag="VVK04_001340"
     CDS             9348..10457
                     /locus_tag="VVK04_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU3989994.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11103..11450
                     /gene="ssrA"
                     /locus_tag="VVK04_001341"
     tmRNA           11103..11450
                     /gene="ssrA"
                     /locus_tag="VVK04_001341"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11694..12470)
                     /locus_tag="VVK04_001342"
     CDS             complement(11694..12470)
                     /locus_tag="VVK04_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HEU3989995.1"
                     /translation="MNATDIKNTYLNYIKENAVFNDVTDTHTEVITPFIDPLGEAIGF
                     SIKSNGKHLTVTDDGYTIWNLSINNIDVTKKGRRQDIFNSLLHFNGFDLHDGAIERTT
                     GKEHLGQVIHDMTQLLMNVYDFIQLTPNNIKSQFLDDVKSYFMKNEHYTVFPAFSIAG
                     KSRLEHRFNFVFMSKGISKIARVHNNITKQQVDTILASWLDTSEYRRKEYGDTEQLYI
                     IVSDEGYNNIKDDHQIALQEYGINILNFSDKEQLEIQLGK"
     gene            complement(12497..12967)
                     /locus_tag="VVK04_001343"
     CDS             complement(12497..12967)
                     /locus_tag="VVK04_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3989996.1"
                     /translation="MKELLLTDSEAKALIKIIKAIANKHNRTLTNRSSGTINLVGKHD
                     TRFILNYFYSTTSKVFHLRETQHNYTLLRINLNNKFHKNANGEKVWGNRVNIFSEEEY
                     YQKGDETTHYKAYPLPYEDILNTDDFLDMLDNLLDYTNVNNPENIAINIQEDLL"
     gene            complement(13022..13486)
                     /locus_tag="VVK04_001344"
     CDS             complement(13022..13486)
                     /locus_tag="VVK04_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HEU3989997.1"
                     /translation="MSKVVKVTGAEVVISHNEEYLKVNPSELNFVPKLGDEVEVHKVD
                     GEIIVIKVKDKKDDKININIVNENNAMQNQSQVVHTQEIATGVHYVNKWVYVILALFL
                     GGLGIHHFYAGYNGKGFLFLILSLTGIPAIIALFQGIIALFKKPDVYGRIAV"
     gene            complement(13842..13929)
                     /locus_tag="VVK04_001345"
     tRNA            complement(13842..13929)
                     /locus_tag="VVK04_001345"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13893..13895),aa:Ser,seq:gga)
     gene            14091..14831
                     /locus_tag="VVK04_001346"
     CDS             14091..14831
                     /locus_tag="VVK04_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU3989998.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAVSLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            14828..15739
                     /gene="pfkB"
                     /locus_tag="VVK04_001347"
     CDS             14828..15739
                     /gene="pfkB"
                     /locus_tag="VVK04_001347"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU3989999.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVELVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAELIKETYGKVEVEKR"
     gene            15736..17688
                     /locus_tag="VVK04_001348"
     CDS             15736..17688
                     /locus_tag="VVK04_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU3990000.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            17852..20077
                     /locus_tag="VVK04_001349"
     CDS             17852..20077
                     /locus_tag="VVK04_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU3990001.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(20122..20550)
                     /locus_tag="VVK04_001350"
     CDS             complement(20122..20550)
                     /locus_tag="VVK04_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990002.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            20688..21830
                     /locus_tag="VVK04_001351"
     CDS             20688..21830
                     /locus_tag="VVK04_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU3990003.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHSLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDGVQALTKIPTEKYLTERVDFATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            21839..23053
                     /gene="thiI"
                     /locus_tag="VVK04_001352"
     CDS             21839..23053
                     /gene="thiI"
                     /locus_tag="VVK04_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU3990004.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            23188..24012
                     /locus_tag="VVK04_001353"
     CDS             23188..24012
                     /locus_tag="VVK04_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU3990005.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            24034..24369
                     /locus_tag="VVK04_001354"
     CDS             24034..24369
                     /locus_tag="VVK04_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEU3990006.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGLVQFFTLSSLDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVSLMA"
     gene            24366..24773
                     /locus_tag="VVK04_001355"
                     /pseudo
     CDS             24366..24773
                     /locus_tag="VVK04_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            24786..25952
                     /locus_tag="VVK04_001356"
     CDS             24786..25952
                     /locus_tag="VVK04_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU3990007.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
BASE COUNT         7720 a         4829 c         5673 g         7981 t
ORIGIN      
        1 cactacaaat attatagagc ccaaaatcct ttgtttacta aacaagggat ttttcttttg
       61 tctctgctcc ttttttgata taatagttct atgttaaaat cagaaaaaca atcacgttat
      121 caaatgttaa atgaagaatt gtccttccta ttggaaggcg aaaccaatgt tttggctaat
      181 ctttccaacg ccagtgctct cataaaatca cgttttccta ataccgtatt tgcaggcttt
      241 tatttgttcg atggaaagga attggtttta ggtcccttcc aaggaggtgt ttcctgcatc
      301 cgtattgcac taggcaaggg tgtttgtggt gaggcagctc actttcatga aactgttatt
      361 gttggagatg tgacgaccta tctcaactat atttcttgtg atagtctagc taaaagtgaa
      421 attgtggtgc cgatgatgaa gaatggtcag ttacttggag ttctggatct ggattcttca
      481 gagattgagg attacgatgc tatggatcga gattatttgg aacaatttgt cgctattttg
      541 cttgaaaaga caacatggga ctttacgatg tttgaggaaa aatcttaatg tatcaagcac
      601 tttatcgaaa atatagaagt caaaacttct cccagttagt tggtcaagaa gttgtggcta
      661 agactcttaa acaagcggtg gagcaagaga aaataagtca cgcttatctt ttttctggtc
      721 ctcgtggaac gggaaaaacc agtgttgcta aaatctttgc caaggctatg aactgtccca
      781 atcaagtggg tggcgaacct tgcaataact gctatatttg tcaagcagtg acggacggta
      841 gtttagaaga tgtcattgaa atggatgcag cttctaataa tggggtagat gaaattcgcg
      901 aaattcgtga taaatctacc tatgcgccta gccttgctcg ttataaggtt tatatcatag
      961 atgaggttca catgctgtct acaggggctt ttaatgccct cctaaagacg ctggaagaac
     1021 caacacagaa tgtagtcttt attttggcca ctactgaatt gcacaagatt cctgctacta
     1081 ttctatcccg tgtgcaacgt tttgagttta aatcaattaa gacacaggat attaaggaac
     1141 atattcacta tatcttagaa aaagaaaata tcagttctga accagaggct gtggaaatca
     1201 ttgccagacg ggcggaaggt ggaatgcggg acgccttgtc tattttggat caagccctga
     1261 gtttgacaca gggaaatgag ctgacgactg ctatctctga agaaattact ggcaccatta
     1321 gcctatcagc cttggatgat tatgtggcgg ccttgtctca acaggatgtt cccaaagctt
     1381 tgtcttgttt gaatcttctt tttgacaatg gtaagagcat gactcgtttt gtgaccgatc
     1441 ttttgcacta tttaagagac ttgttaattg ttcaaacagg gggagaaaat actcatcata
     1501 gttcagtctt tgtagaaaat ttggcacttc ctcaaaaaaa tctgtttgaa atgattcgct
     1561 tagcaacagt gagtttagca gatattaagt ctagtttgca gcccaagatt tatgctgaaa
     1621 tgatgaccgt ccgtttggcg gaaatcaagc ccgaaccagc tctatcagga gcggttgaaa
     1681 atgaaattgc tacgctgaga caggaagttg cccgtctcaa acaagagctt tctaatgtag
     1741 gtgcggttcc taaacaagtt gcaccagctc ctagtcgacc agctacgggc aaaacagtct
     1801 atcgtgtcga tcgcaataaa gtgcaatcta tcttacaaga ggccgtcgaa aatcctgatt
     1861 tagcacgtca aaatttaatt cgtttgcaga atgcctgggg agaggtaatt gaaagtctag
     1921 gtgggccgga caaggctctg ctagttggtt ctcaaccggt tgctgccaat gaacaccatg
     1981 ctattcttgc ttttgagtct aacttcaatg ctggtcaaac tatgaaacga gacaatctca
     2041 ataccatgtt tggtaatatc ctcagtcagg cggcaggttt ttcacctgag attttagcta
     2101 tttccatgga ggaatggaaa gaagttcgcg cagccttttc agccaaagcc aaatcttctc
     2161 aaactgaaaa agaagtagaa gaaagcctga ttccagaagg atttgaattt ttggctgata
     2221 aagtgaaggt agaggaagac taaagaaaga tttcatgata caataagttt atgaataaac
     2281 aacaatttat tattatggcg ctgtttacag ctgctgagac ctattttttc aatgaagcct
     2341 ggatgactgg ccgctatatt atggcagcct tttgggcaat tttactcttt agaaatttcc
     2401 gagtcagtta tgtgatgggc aaaatcgttg atgtcatcga tcagcatttt aataggaaag
     2461 actagccctc agcttccaga caaaatcaaa gccttttagg cttttttttg ttatactaga
     2521 aaagtatatt tatagaattt ttgctctatt tctggggaaa tcagacgttt ttctagtaag
     2581 tactgtaaaa gttttgaaaa agaaaggaac tatcatgtca gtattagaga ttaaagatct
     2641 tcacgttgag attgaaggaa aagaaatttt aaaaggggtt aacctgaccc tgaaaacagg
     2701 agaaattgcc gctatcatgg gaccaaatgg tacaggtaaa tcgactcttt ctgccgctat
     2761 catgggaaat ccaaactatg aagtaactaa aggtgaagtt ttgtttgatg gcgtaaacat
     2821 ccttgagttg gaagtggatg agcgtgcgcg tatgggactt ttccttgcta tgcaataccc
     2881 atcagaaatc cctggaatta ccaatgctga gtttcttcgt gccgctatga atgcgggtaa
     2941 agaagatgat gagaagattt cagttcgtga gtttattact aagctagatg aaaaaatgga
     3001 attgctcaac atgaaagaag aaatggcaga gcgttacctc aacgaaggct tctctggtgg
     3061 tgagaaaaaa cgcaatgaaa ttcttcaact tttgatgttg gagccaacat ttgctctttt
     3121 ggacgagatt gactcaggtc ttgatattga cgctcttaaa gttgtgtcta aaggtgtcaa
     3181 tgccatgcgt ggtgaaggtt ttggtgctat gatcatcact cactaccaac gtcttttgaa
     3241 ctatatcaca cctgatgtgg tacacgtgat gatggaaggt cgtgttgtcc tttctggtgg
     3301 tccagaattg gctgcgcgtt tggaacgtga aggatacgca aaattagctg aagaacttgg
     3361 ctacgactac aaggaagaat tgtaatttcc tcgtatcttt taggagaagt aaatgactag
     3421 agaaaatatt aaactttttt cagaaatgca cgctgaacca agctggttgg ctgatctccg
     3481 tcaaaaagct tttgacaaga ttgagacttt ggaattacca gttattgagc gtgtcaaatt
     3541 ccaccgttgg aatctgggtg atggaacgat tacagaaaat gagccatcag caaatgttcc
     3601 aaatttcaca gctttagatc atcacttgaa gttggtgcaa gtaggaactc aaactgtttt
     3661 cgaacaaact ccagttgagt tagctgaaca gggtgttgtc ttcacagact ttcactcagc
     3721 tttagaagaa attccagagc tgatcgaaga attcttcatg tcatctgtta agtatgatga
     3781 tgacaagttg gcggcttacc acacagctta ctttaacagt ggtgctgtac tctatattcc
     3841 agataacgta gaaatcacag agccaattga aggaattttc taccaagata gcgatagcaa
     3901 tgtgccgttt aacaagcata ttatgattat cgctggtaaa aattctaaga ttagttatct
     3961 ggagcgttta gagtcacgcg gtgaaggaag tgacaaagca actgccaata tcacagtgga
     4021 agtgattgca cgttctggtg cgcaagtcaa gtttgctgct atcgaccgac taggtgaaaa
     4081 cgtcactgcc tacattagcc gtcgtggtaa attaggcaac gatgcaagta ttgattgggc
     4141 aatcggtgtc atgaacgaag gaaatgtcgt tgctgatttt gatagtgact tgattggtaa
     4201 tggtagccat gcggacctca aggtagtagc actttcaagt ggtcgtcagg tacaagggat
     4261 tgatactcgt gtaactaact atggctgcaa ctcaatcgga aacattctac aacatggggt
     4321 tatccttgaa aaagcaactt tgactttcaa tggtatcggc cacatcatca agggtgctaa
     4381 gggagcagat gcgcaacaag agagccgtgt tctcatgctt tcagaccaag cgcgttcaga
     4441 tgctaaccca attcttttga ttgatgaaaa tgacgtaact gcaggacatg cagcctctat
     4501 tggtcaggta gatccagaag acatgtatta cctcatgagt cgtggattgg ataaggcaac
     4561 tgcagagcgt ttggttgttc gtggtttcct tggatctgtt atcgtggaga ttccagtcaa
     4621 ggaagttcgt gatgaaatga ttgcaactat cgaagagaaa ttgtcaaaac gctaagggga
     4681 agcctatgtt agatgtagaa gcgattcgca aggattttcc aattttagat cagattgtca
     4741 atgatgaacc tctggtctat ctggacaatg ctgcgacgac acaaaaacca ctagtagttc
     4801 tgaatgctat taacagctac tatgagcagg acaatgccaa tgttcaccgt ggtgtccata
     4861 ccttagcgga acgagcgaca gcttcttatg aagctgctcg tgaaaccatt cgtaagttta
     4921 ttaatgcagg ctctacaaag gaagttctct ttaccagagg aacgacaacc agccttaact
     4981 gggtggcacg ctttgctgag gaaattctcg ctgagggaga ccaggtcttg atttcagtaa
     5041 tggaacacca ttctaatatc attccatggc aggaagcttg tcgaaagact ggagcagagc
     5101 ttgtctatgt ctatcttaaa gacggtgcct tggatatgga ggatttgcga gctaaattga
     5161 ctgataaggt taaatttgtt tccctagctc atgcctccaa tgttcttggt gtggtcaatc
     5221 cgatcaagga aatcactcaa ttagcccacc aagttggggc aattatggta gtggatggtg
     5281 ctcaatctac acctcatatg aagattgatg tccaggactt ggatctggac tttttcgcct
     5341 tttcgggtca caagatggct ggtccgactg gtatcggtgt cctttacggc aaagaaaagt
     5401 atcttgagca aatgtctcca gtagaatttg gcggcgagat gattgatttt gtctacgagc
     5461 aatttgctag ttggaaggaa ttgccttgga aatttgaggc tggaacgcca aatatggcag
     5521 gagctattgg acttgcgact gcagttgatt atctggaaaa gattggtatg gatgccgttg
     5581 aagctcatga acaggaattg attgcgtacg tctatccaaa actgcaggca attgagggat
     5641 tgaccattta cggttctcag gatttggctc aacgttcggg tgttattgcc tttaacctag
     5701 gtgatctcca tcctcacgat cttgcgacgg ctctggatta tgaaggagtg gctgttcgtg
     5761 ctggtcacca ttgtgcgcaa cccttgcttc agtatttgga agtcccagca acagctcgtg
     5821 caagttttta tatctacaat accaaggcag attgcgacaa actagtcgat gccctacaaa
     5881 agacaaagga gtttttcaat ggcactttct aaactagata gcctttatat ggcagtggta
     5941 gcagaccatt cgaaaaatcc acatcaccaa gggaagttag aagatgctga gcaaatcagt
     6001 ctcaacaatc cgacttgtgg ggatgtcatc aacctctctg tcaagtttga tgcagaggac
     6061 cgtttggaag atattgcttt tctaaattca ggatgcacga tttcaactgc ttctgctagt
     6121 atgatgacag atgccgtttt aggaaaaacc aaacaagaaa ttttagaact ggcgactatt
     6181 ttttctgaaa tggttcaagg gcaaaaagat gagcgtcaag accaacttgg agacgcggca
     6241 ttcttgtcag gtgttgccaa attccctcaa agaatcaagt gtgcaaccct agcttggaat
     6301 gcccttaaga aaacaattga aaatcaagaa aaacagtaag acaagtttct tttgtcttat
     6361 gaattattag aaatgaagaa agaaaggata ttatggctga agaaagagta gaaccaaaac
     6421 caattgacct tggtgaatat aaatttggtt tccatgacga tgtagagcct gtcttatcga
     6481 caggaaaagg actcaacgaa ggtgttattc gtgaattatc tgctgctaag ggtgagcctg
     6541 agtggatgtt ggagttccgt ttgaagtctt atgaaacctt caaaaaaatg cccatgcaaa
     6601 cttggggagc agacttgtca gagattgact ttgatgactt aatctactac caaaaaccat
     6661 ctgacaaacc agcccgttct tgggatgatg tacctgaaaa gattaaagaa acctttgaac
     6721 gtatcgggat tccagaagct gaacgtgctt atttagcagg ggcttctgcc cagtacgagt
     6781 cagaagtggt ttaccacaac atgaaggaag agttccaaaa attaggtatt atctttacag
     6841 atacagattc cgcactcaag gaatacccag acttatttaa acaatacttt gcgaagttgg
     6901 taccgccgac agataacaag ttggcagccc tcaactcagc agtatggtcg ggtggaactt
     6961 ttatctacgt gccaaaaggt gtcaaggtag atattccact tcaaacttat ttccgtatca
     7021 ataacgaaaa tataggtcag ttcgaacgta ccttgattat cgttgatgag ggagcaagcg
     7081 tccactacgt agaaggatgt acagcaccaa catattcaag caatagctta cacgctgcca
     7141 ttgtagaaat ttttgctttg gacggagctt atatgcgtta tacaactatc caaaactggt
     7201 ctgataacgt ctataacttg gtaacaaagc gtgctaaggc tcaaaaggat gccactgttg
     7261 agtggattga tggaaacttg ggtgccaaaa cgactatgaa atatccatct gtttaccttg
     7321 atggagaagg agcgcgtggt accatgctct ctatcgcctt tgctaatgca gggcaacacc
     7381 aagacacggg tgctaagatg attcacaatg ctccacatac cagctcgtct attgtgtcta
     7441 aatccatcgc taaaggtgga ggaaaggttg actaccgtgg acaagtcacc tttaacaaga
     7501 actctaagaa atctgtttcc cacattgaat gtgataccat tatcatggat gacttgtcag
     7561 catcagatac tattccattt aatgaaattc acaactcgca agtagctttg gaacacgaag
     7621 ccaaagtatc taagatttca gaagagcaat tgtattatct catgagccgt ggattgtcag
     7681 aatctgaggc aactgaaatg attgtcatgg gatttgtaga accctttaca aaagaacttc
     7741 caatggaata cgcagttgag ctgaaccgct tgattagcta tgaaatggag ggatcagttg
     7801 gataaaattt gattttatac tcttcgaaaa tctcttcaaa ccacgtcagc atcgccttac
     7861 cgtatgtatg gttactgact tcgtcagttt catctacaac ctcaaaacag tgttttgagc
     7921 aacctgcggc tagcttccta gtttgttctt tgattttgaa gatgaacttg tatcaaaaaa
     7981 tcgcggttta aaatcgcgat tttttataat ttctcgttaa caaagcggac aaactgattc
     8041 caccaaactt ttaagaagaa ggctttttca attttcttgt ctgctaccat ttcgaaacta
     8101 gggcgctctg tggtgatgta accttgacca atcaagtcct tgtcttcata agtcaaatgg
     8161 ccaaccactg ttccagcttc aagtggtgct gggattgctt tggaatcagg tgtgaattga
     8221 acagattggg aagattgatt cccaacacgt tctattagat agatatcctc tggagccact
     8281 gcagttactg tatcttcttt tccatcttgt acaggggttt tgctatcttg ataggcatcg
     8341 ccttgttgaa cgattttgcg aagtgtaaat gtagaagaaa tataatccat tagggaagat
     8401 gtagctgtaa atcgagcgta aggattattg tcttgatgat ctgcatttaa aacaactgtg
     8461 atgactctca tgcctttttc gacagtagta ccaacaaaag actctccagc cttatctgtt
     8521 gttcctgttt ttagcccatc aaaaccacca cggtaagcag gcataccttc taacatgtag
     8581 ttggttgaag tgattgtcat cccagcaaaa gtagaagaag gttttttggt gatttctaag
     8641 acttgtgggt attttttgat gaggttgcga gcaacgatag cgacatcata agcactaagc
     8701 ttattttcct catctttttt agaacctggg taaatgttat cccctagagt ttcattgtta
     8761 agacctgtcg tattgacaac agtggcatcc tgaattcccc attccaagag ttttgcccgc
     8821 atcatatcga cgaaatcttt ttctgagcca gcaattttct cagctagggc aatagcggcg
     8881 ctgttggcac tagataccag agttgcttca agcaactctt cgacagtata attacgggcc
     8941 tccataggaa tattactggc ttcagaattt gtcgtcaatt gataaggata atcagaaata
     9001 tctacaggag tggagagggt aatacttccg ttttccaaag cttcatagac cagataaaca
     9061 gtaatcaatt ttgttatgga agcaatttcg acaggttgcg ttgcatcctt ctcatagaga
     9121 attttaccag tatttgcctc aacagcaatc gcatgtttag cggcaatggt aaaatcttga
     9181 gcaacagcag tagaagcacc ccctaaaaga gagacagtta acaaagttaa aaatattttt
     9241 ttcatagtag tcttattcta tcataaagaa aaaaaatatt cttgctttaa taattcatct
     9301 gttaagcttt ttgaaaatat ggtaaaataa agtgagggag gtaactcatg tttcgtagaa
     9361 ataaattatt tttttggacc acagaaattt tactcttaac catcatcttt tacctatgga
     9421 gacagatggg atctttgatt aacccttttg ttagcgtgct taatacaatt atgattccat
     9481 ttttattagg gggctttctt tattatttga caaaccctat tgttactttc ttaaataaag
     9541 tctgtaaact caatcgtttg cttggtattt taattacctt gtgtactttg gtctggggaa
     9601 tggtcatagg tgttgtctat ctcttaccta ttttgattaa tcagttatct agtttgatta
     9661 tatctagtca aactatttat agtcgagtac aagacttaat catagactta tctaattatc
     9721 ctgcgctcca gaatttggat gtagaagcta caattcagca gttaaactta tcctatgtgg
     9781 atattcttca aaatatccta aatagcgtat caaatagtgt agggagcgtc ttgtcagctc
     9841 ttatcagtac tgttttgatt ttgattatga ctccagtttt tttggtttat ttcttattag
     9901 atggacataa attcttgccc atgcttgaaa gaacgattct aaagagggat cgcttgcata
     9961 ttgcaggctt attaaagaat ttaaatgcga cgattgctcg ctatattagt ggagtttcga
    10021 ttgacgcaat cattataggt tgtttggctt atattggcta tagtattatt ggtttaaaat
    10081 atgctttagt ttttgccatt ttttctggtg tagccaattt aattccttat gtggggccaa
    10141 gtattggttt gattcctatg atcatcgcaa atatattcac tgatccccat agactgctga
    10201 ttgcagtgat ttatatgctt gttgttcagc aggtagatgg caatatctta tatcctcgaa
    10261 tcgtaggaag tgttatgaag gttcatccaa tcacgatttt agttttactt ttgttgtcaa
    10321 gcaatatcta tggtgtagtt ggaatgattg tcgcagtgcc aacctattct atcttgaaag
    10381 aaatttctaa gttcttatcc cgtttgtatg aaaatcataa aataatgaaa gaacgagaaa
    10441 gagaattagc taagtaaaag tcaggagaac cctgattttt ctttactgga agtggccttt
    10501 agattagaag actgaaaata agttaaagtc ttaaactaat tttcacagct aagaatagta
    10561 gaagttaatc tgataaaaat cgaaaaaacc agtggaattc cgtgtcaggg taagttccac
    10621 tggttttcat agtctattaa agttcgaatg aaacctattt atagtatatt gaaactagaa
    10681 tagtacacct ctaattctaa aacattgtta gaaatcgatt tgactgtcct gatctattcg
    10741 tcctattctt atttcatttt actatatttt ggtgcaataa gtgaaaagta gtccgaataa
    10801 tataaggatt gattttatag tttttaaact caaatgaatt aaaataaaga gagtacgaaa
    10861 attctcatct gaaagtattt tagaataatt ctcttcgtga atttcttcaa aacagatagc
    10921 ttcatcttag gtatgtgtta attggatttc gtaagctcta tttacaatcg taaagttatg
    10981 cactgaaaaa gttgtagtta gtcttccagt ttgctaaatt tctcgaatag tatctttttt
    11041 aggtatgtga tttctttttg catttttgag ttagataagg tataatggtt ttattgtctt
    11101 ttggggtcgt tacggattcg acaggcatta tgaggcatat tttgcgactc gtgtggcgac
    11161 gtaaacgctc agttaaatat aactgcaaaa aataacactt cttacgctct agctgcctaa
    11221 aaaccagcag gcgtgacccg atttggattg ctcgtgttca atgacaggtc ttattattag
    11281 cgagatacga ttaagccttg tctagcggct tgataagaga ttgatagact cgcagtttct
    11341 agacttgagt tatgtgtcga ggggctgtta aaataataca taacctatgg ttgtagacaa
    11401 atatgttggc aggtgtttgg acgtgggttc gactcccacc ggctccatta ttcctttgca
    11461 ttcttttgca ttccttggta aaacgttgtt aaatcaacgt tttttatttt tatctttggt
    11521 attcctttgc attcttttgc taaaaaggga gtcacaaaca gaccctattt taaaaaaagg
    11581 atagaaaaaa ggatacaaca tttgtcgcat cctagaaatc tatgtacttc gtaaagcgtt
    11641 ctccgattcg agtattcctc tgcatgcttt agtaaatata ggattttttg tagttacttc
    11701 cctaattgga tttctaattg ttctttatct gagaaattca aaatgttaat accatactct
    11761 tgtagagcga tttgatggtc atctttgata ttattatacc cttcatcgct tacaatgata
    11821 tacaactgtt ctgtatctcc atattctttt ctacggtatt cagatgtatc taaccaacta
    11881 gctaagatag tatcaacttg ttgtttggtt atgttattgt gaactctggc tatttttgaa
    11941 atacctttac tcataaacac aaaattaaag cggtgttcta aacgagattt acctgcaatt
    12001 gagaaagctg gaaagactgt gtaatgctca tttttcatga agtaagattt aacatcgtct
    12061 aaaaattgag atttaatatt gttaggtgtt agctgaataa agtcataaac attcatcagc
    12121 aattgtgtca tatcatgtat gacttgtcct agatgttctt taccagtcgt ccgttcgatt
    12181 gctccatcgt gtaaatcaaa tccattaaag tggagaagtg agttaaagat gtcttgacgt
    12241 cgcccttttt ttgtaacatc aatattatta atggataaat tccagatagt ataaccatca
    12301 tctgtaactg tcaaatgttt tccattgctt tttattgaga aaccaatagc ttcacctaat
    12361 gggtctataa aaggagtaat cacttcagta tgagtatcag tcacatcgtt aaaaacagcg
    12421 ttttctttta tgtaatttag ataggtattt ttgatatcag tagcattcat gatattctcc
    12481 tttctttata gggtgattat aacaaatcct cttgtatatt aattgctata ttttcaggat
    12541 tgttcacatt ggtatagtca agcaaattat caagcatatc caggaagtca tcagtgttaa
    12601 gaatatcttc ataaggtagt ggataggctt tgtaatgagt tgtttcatcc cctttttgat
    12661 aatactcttc ttcagagaag atgttaactc gattgcccca aactttctcg ccgtttgcgt
    12721 tcttatggaa tttattattt agattgattc gtaagagagt atagttgtgt tgagtttccc
    12781 ttagatgaaa aactttgctt gtagtgctgt agaagtagtt caaaataaat ctagtatcat
    12841 gcttgccaac aaggttaata gtacctgaac tgcgattcgt aagagttcga ttgtgtttat
    12901 tagcaattgc tttaattatt tttatgagag ctttagcttc actatctgtc agaagtaact
    12961 ctttcatatc tttcctttct actttatcta cattctagag agtggaaatc tggaatgtag
    13021 atcagacagc gatccttccg tatacatctg gtttcttaaa gagagctatg atgccttgga
    13081 aaagtgcaat aatagcaggt attcctgtta aagataaaat cagaaaaagg aaaccttttc
    13141 cgttatatcc tgcgtaaaaa tgatgtatac ccaatccacc taaaaataaa gcaagaataa
    13201 cataaaccca cttattaaca taatgtacac ctgtagctat ttcttgagtg tgaacgactt
    13261 gtgactgatt ttgcatagcg ttgttttcat tgacaatgtt aatattaatt ttgtcgtctt
    13321 ttttatcttt aacttttatg acgataatct caccatctac tttatgaact tcgacttcgt
    13381 cacctaattt tggaacaaaa ttcaattcag atggatttac ttttaaatac tcttcattat
    13441 gggagattac aacctctgct cctgtaactt taacaacttt tgacattttg tttttccttt
    13501 cattttacca tctatagatt ttaataatga gctttgatat ttattttatc tgtttttata
    13561 agtaaagtat atcaaaaaaa gtacgaaaag aaaatctttt atggtttagt taaaaagcaa
    13621 gagtttaaga aactggatta attaaacttg aagtatttga gattttgtct tttactgttc
    13681 gtaaaatcgt atgagataag aagggagtgg aaagaattca tactctctct agaacttgta
    13741 tattgaaacg atgtggagat tgtaaagaaa ttacaaaata ccccaaaact aagatagaaa
    13801 tacaaagttt cagggtatca tatattttat ctgtttttcc acggaagaca tgggattcga
    13861 acccacgcac gctattacac gcctaccgcg tttccaacac ggcctcttaa gcctcttgag
    13921 taatcttcca atacttactc aaatagtcta ccataaaggc tcttatcttg caataaaaat
    13981 tctagaaata agaaaaatga tagattttga aagaaaatga taaaaaatgc ttgacttcaa
    14041 aagaaagtat gatagaatga atagtgtaaa cgataacagg aggtgattcg gtgttaaaaa
    14101 cagagcggaa gcaactgatt ttagaggagt taaatcaaca tcatgtagtt tctctagaaa
    14161 aattagttag tttgctagaa acgtcagaat caacggttcg aagagacttg gatgagttgg
    14221 aagcggaaaa caagcttcgt cgtgtgcatg gtggagcaga actcccccac tccttacagg
    14281 aagaagaaac cattcaagaa aaatctgtca aaaaccttca agaaaagaag ttgctggctc
    14341 agaaagcagt ctctctcatt aaagaaaaag atgtcatctt tatcgatgct ggaacaacaa
    14401 ctgctttttt gattcatgaa ttggtcaata agaatgttac agttgtgacc aactccattc
    14461 accatgccgc tcagttggtt gaaaagcaga ttccaactgt catggttgga ggaaacgtca
    14521 agacggcgac agatgctagt atcgggggcg ttgctcttaa ccagattaac caattgcact
    14581 ttgaccgtgc ctttatcgga atgaatggtg ttgacgatgg ctattatacg actcctgata
    14641 tggaggaggg agctgtgaaa agagctattt tggagaatgc caagcagacc tacgtcttgg
    14701 tggattcgtc aaaaattgga caaacttgct ttgccaaggt agccccactc aaacgcgcta
    14761 tcgttatcac tagtcaaggg catgagctct tgcaggttat taaggagaaa acggaggtaa
    14821 tagaagtatg atttatacag tcacactcaa tccatccatt gactatatcg ttcgtttgga
    14881 ccaagtcaaa gttggtagtg taaatcgtat ggacagtgat gataagtttg ctggtgggaa
    14941 aggaatcaat gtcagccgtg tcttgaaacg tttgaatata ccaaatacag cgacgggatt
    15001 tatcggtggc tttactggta aatttatcac agatacttta gcagaggaag aaatcgagac
    15061 acgttttgtc caggtggcag aagatactcg tatcaatgtt aaaattaaag cagaccaaga
    15121 aacagaaatc aacggaacgg gtccaactgt tgaactggtt cagctagaag aattgaaagc
    15181 tattttatct agtctgacag cagaagatac agttgtcttt gcaggttcaa gtgctaaaaa
    15241 tctaggtaat gttatctata aggatttgat ttccttgacg cgccagactg gtgcgcaagt
    15301 ggtctgtgac tttgaaggac agaccttaat tgatagtttg gactaccagc ctcttcttgt
    15361 aaaaccaaac aatcatgaac ttggagcgat ttttggggtt aaactcgaaa gtttagatga
    15421 aattgagaaa tacgctcgtg agttactggc taagggtgct caaaatgtta ttatctctat
    15481 ggctggggac ggtgctcttc ttgtcacatc tgagggagct tactttgcta aaccaatcaa
    15541 aggaacagtc aaaaattcag ttggggctgg tgattctatg gttgctggat tcacaggtga
    15601 atttgtcaaa tcaaaagacg cagtagaagc cttcaaatgg ggagtggctt gcggaacggc
    15661 aactaccttc tcagatgact tggcaacggc agaacttatt aaagaaacat atggaaaagt
    15721 tgaggtagaa aaacgatgaa aattcaagac ctattgagaa aagatgtcat gttgctagat
    15781 ttgcaggcaa ctgaaaaaac agctgtcatc gacgagatga ttaaaaattt gacagaccac
    15841 ggttatgtaa cagattttga aacatttaaa gaaggaattt tggcgcgtga agctttgact
    15901 tctactggtt tgggtgatgg aatcgcaatg cctcacagca aaaacgctgc tgtcaaagaa
    15961 gcgacagttc tatttgctaa gtcaaataag ggtgttgact acgagagctt ggatggacaa
    16021 gcaactgacc tcttcttcat gattgcagct ccagaaggtg ccaatgatac tcacttggca
    16081 gccttggcag aattgtctca atacttgatg aaagacggtt ttgcagacaa acttcgtcaa
    16141 gcaacatctg cagaccaagt tatcgaactt tttgaccaag cttcagaaaa aactgaggaa
    16201 cttgttcaag cacctgctaa tgactctggt gactttatcg tagctgttac agcttgtaca
    16261 acaggtattg cccacactta catggcccaa gaagcccttc aaaaagtagc tgctgaaatg
    16321 ggggttggta tcaaggtcga aaccaacggt gctagcggtg ttggaaatca actaactgca
    16381 gaagatatcc gtaaggctaa agctattatc attgcagcag acaaggccgt tgaaatggat
    16441 cgatttgatg gaaaaccatt gatcaatcgt ccagttgctg acggtatccg taagacagaa
    16501 gagctaatta acttggctct ttcaggagat actgaagtct accgtgccgc taatggtgca
    16561 aaagctgcaa cagcctctaa cgaaaaacaa agccttggtg gtgccttcta caaacacttg
    16621 atgagtggtg tatctcaaat gttaccattc gttatcggtg gtggtatcat gattgccctt
    16681 gccttcttga ttgacggtgc tttgagtgtt ccaaatgaaa accttggcaa tcttggttct
    16741 taccatgagt tagcttctat gttcatgaaa attggtggag ctgcctttgg tttgatgctt
    16801 ccagtctttg cgggttatgt tgcctactct attgctgaaa aaccaggttt ggtagcaggt
    16861 ttcgtggctg gtgctattgc caaagaaggt tttgcctttg gtaaaattcc ttatgccgca
    16921 ggtggtgaag caacttcaac tcttgcaggt gtctcatctg gtttcctagg tgcccttgtt
    16981 ggtggattta tcgcaggtgc cttggttctt gccatcaaga aatacgttaa agttcctcgt
    17041 tcactcgaag gtgctaaatc aatccttcta ttgccacttc ttggaacaat cttgacagga
    17101 tttgttatgc tagctgtgaa tatcccaatg gctgcaatca acactgctat gaatgacttc
    17161 ctaggtggtc ttggaggagg ttcagctgtc cttcttggta tcgtccttgg tggaatgatg
    17221 gctgttgaca tgggtggacc agttaataaa gcagcttatg tctttggtac aggtacgctt
    17281 gcagcaactg tttcttcagg tggttctgta gccatggcag cagttatggc tggaggaatg
    17341 gtgccaccac ttgcaatctt tgtcgcaact cttcttttca aagataaatt tactaaggaa
    17401 gaacgtaact ctggtttgac aaacatcatc atgggcttgt catttatcac tgagggagcg
    17461 attccatttg gtgccgctga cccagctcgt gcgattccaa gcttcatcct tggttcagca
    17521 gtagcaggtg gactcgttgg tcttactggt atcaaactca tggcgccaca cggaggaatc
    17581 ttcgttatcg cccttacttc aaatgctctc ctttacctcg tttctgtctt ggtaggagca
    17641 atcgtaagtg gtgtggttta tggttaccta cgcaaaccac aagcataaaa aatagaaaaa
    17701 tgaaaagatt ggaccgtttg gtgcagtctt tttctcttcc cgaaatgcct gtgaaatatg
    17761 gtataataga agaatggcaa acaagaatac aagtacaaca agacggagac cgtctaaagc
    17821 agaactggaa agaaaagaag cgattcaacg aatgttgatt tcgttaggaa ttgcgatttt
    17881 attgattttc gcagccttca aattaggggc tgcaggtata accctttata atttaattcg
    17941 cttgctagtg ggtagcctag cttatctggc gatattcggc ctattaatct atctcttctt
    18001 tttcaagtgg atacgaaaac aggaaggact cttatctggt tttttcacca tatttgctgg
    18061 cttactcttg atttttgagg cctacttggt ttggaaatat ggtttggaca agtccgttct
    18121 aaaagggacc atggctcagg ttgtgacaga tctgactggt tttcgaacga ctagctttgc
    18181 tggagggggc ttgatcgggg tcgctcttta tattccaaca gcctttctct tttcaaatat
    18241 cggaacttac tttattggtt ctatcttgat tttagtgggt tctctcctag tcagcccttg
    18301 gtctgtttac gatattgctg aatttttcag tagaggcttt gccaaatggt gggaagggca
    18361 cgagcgtcga aaagaggaac gctttgtcaa acaagaagaa aaagctcgcc aaaaggctga
    18421 gaaagaggct agattagaac aagaagagac tgaaaaagcc ttactcgatt tgcctcctgt
    18481 tgatatggaa acgggtgaaa ttctgacaga ggaagctgtt caaaatcttc cacctattcc
    18541 agaagaaaag tgggtggaac cagaaatcat cctgcctcaa gctgaactta aattccctga
    18601 acaggaagat gactcagatg acgaagatgt tcaggtcgat ttttcagcca aagaagccct
    18661 tgaatacaaa cttccaagct tacaactctt tgcaccagat aaaccaaaag atcagtctaa
    18721 agagaagaaa attgtcagag aaaatatcaa aatcttagaa gcaacctttg ctagctttgg
    18781 tattaaggta acagttgaac gggccgaaat tgggccatca gtgaccaagt atgaagtcaa
    18841 gccggctgtt ggtgtaaggg tcaaccgcat ttccaatcta tcagatgacc tcgctctagc
    18901 cttggctgcc aaagatgtcc ggattgaagc accaatccct gggaaatccc taatcggaat
    18961 tgaagtgccc aactccgata ttgccactgt atctttccga gaactatggg aacaatcgca
    19021 aacgaaagca gaaaatttct tggaaattcc tttagggaag gctgttaatg gaaccgcaag
    19081 agcttttgac ctttctaaaa tgccccactt gctagttgca ggttcaacgg gttcagggaa
    19141 gtcagtagca gttaacggca ttattgctag cattctcatg aaggcgagac cagatcaagt
    19201 taaatttatg atggtcgatc ccaagatggt tgagttatct gtttacaatg atattcccca
    19261 cctcttgatt ccagtcgtga ccaatccacg taaagccagc aaggctctgc aaaaggttgt
    19321 ggatgaaatg gaaaaccgtt atgaactctt tgccaaggtg ggagttcgga atattgcagg
    19381 ttttaatgcc aaggtagaag agttcaattc ccagtctgag tacaagcaaa ttccgctacc
    19441 attcattgtc gtgattgtgg atgagttggc tgacctcatg atggtggcca gcaaggaagt
    19501 ggaagatgct atcatccgtc ttgggcagaa ggcgcgtgct gcaggtatcc acatgattct
    19561 tgcaactcag cgtccatctg ttgatgtcat ctctggtttg attaaggcca atgttccatc
    19621 tcgtgtagca tttgcggttt catcaggaac agactcccgt acgattttgg atgaaaatgg
    19681 agcagaaaaa cttcttggtc gaggagacat gctctttaaa ccgattgatg aaaatcatcc
    19741 agttcgtctc caaggctcct ttatctcgga tgacgatgtt gagcgcattg tgaacttcat
    19801 caaggctcag gcagatgcag actacgatga gagttttgat ccaggtgagg tttctgaaaa
    19861 tgaaggagaa ttttcggatg gagatgctgg tggtgatccg ctttttgaag aagctaagtc
    19921 tttggttatc gaaacacaga aagccagtgc gtctatgatt cagcgtcgtt tatcagttgg
    19981 atttaaccgt gcgacccgtc tcatggaaga actggagata gcaggtgtca tcggtccagc
    20041 tgaaggtacc aaacctcgaa aagtgttaca acaataaaaa aatagcttct ttccgagttt
    20101 ggagggaagc tattttagtg gctattgatt gcttttattt tctgaagttg gcgcattgga
    20161 ctgtttttcg ttttcagtag caggtttact tgaagcagga gtagaagagt cctgagttgc
    20221 tgttttctga tcttcttttt tctcttcctt gacgctagat tttggtgttt cctcttgctg
    20281 tgttttttct tgactagtgt tagtctcttt agttggactg gtgttttcct taggggattc
    20341 cttttggatt tctttgacaa tggttgtcgt ctggcttgtc gtaggttctt ttttaatatt
    20401 tttgttatta tccaaggcgt tcataatcgt gatacttgcg gtaatcaagc caaggatact
    20461 agcgattgta gcaacggttt tttgaaagac tgtaaagcct tttttgatgt gttctgtttt
    20521 tggttttgaa gttctacgat agttagacat acattctctc ctttgattat gatttattat
    20581 actctgtttc tttaaaaaaa tcttaaaaaa agagaaattg ccctttcttg tcgcaagctc
    20641 cgtttcatga tacaatagag gaagtgattt tagaaagcgt gagaaacatg atttactttg
    20701 ataattcagc gacgaccaag ccttatcctg aagcccttga aacctatatg caggtcgctt
    20761 caaaaatttt aggaaaccca tctagtctcc atagtttggg agaccaagca acacgaatct
    20821 tagatgcttc tcgccaacag attgcagatt taatcggtaa gaaaagcgat gaaatcttct
    20881 ttacctctgg tggaacagaa ggggataact gggttatcaa gggtgtggcc tttgaaaaag
    20941 ctcagtttgg caagcacatc attgtttcag ccattgaaca tccagcagtc aaagagtcag
    21001 ccctctggtt gaaaagtcaa ggatttgaag tggattttgc tccagttgat aagaaaggct
    21061 tggtcgatgt tgaggcgtta gcaggtttga tacggcctga tacaatcctc gtttctatca
    21121 tggctgtgaa caatgaaatc ggctctatcc aacctattga ggctatttca gaattcttgg
    21181 cagacaagcc gactatttcc ttccacgttg atggggttca ggcgcttacc aagattccga
    21241 ctgaaaagta tctgacagaa cgagtggatt ttgcgacttt ctctagtcac aagttccacg
    21301 gggttcgagg tgttggcttt gtctatatca aatctggcaa gaagattaca cctcttctta
    21361 caggtggtgg ccaggagcga gattatcgtt cgacaactga aaatgtggca gggattgcag
    21421 cgacagccaa ggccctccgt ttgtctatgg aaaagctaga tatctttagg agcaagactg
    21481 ggcagatgaa ggcagtgatt cgccaagctc ttctgaacta tccggatatt tttgtctttt
    21541 cagatgagga aaactttgca cctcatattc tgacttttgg aatcaaaggt gttcgaggtg
    21601 aagtcatcgt tcacgccttt gaagactatg atattttcat ctcaacaacc tcagcttgtt
    21661 catctaaggc aggaaaacca gccggtacct tgattgccat gggagtggac aaagataagg
    21721 ccaagtcagc tgtgcgtctt agcctagact tggaaaatga tatgagtcag gtcgagcagt
    21781 ttttgaccaa gttaaaattg atttacaatc aaactagaaa agtaagatag gagcattcat
    21841 gcagtattca gaaattatga ttcgctacgg agagttgtca accaagggta aaaaccgtat
    21901 gcgtttcatc aataaacttc gtaataatat ttcggacgtt ttgtctatct atacccaagt
    21961 taaggtaaca gcagatcgcg accgtgccca cgcttacctc aatggagctg attacacagc
    22021 agttgcagaa tctctcaaac aagtttttgg aattcaaaac ttttctcctg tttataaggt
    22081 tgaaaaatct gtagaagttt tgaagtcttc tgtccaagag attatgcggg acatctacaa
    22141 ggaaggtatg acctttaaga tttctagcaa gcgtagcgac cacaactttg aacttgatag
    22201 tcgtgaactc aaccaaacac ttggaggggc tgtattcgaa gccattccaa atgtgcaagt
    22261 tcaaatgaaa agtcctgaca tcaatcttca ggtggagatt cgtgaagaag cagcctatct
    22321 ttcttatgaa accattcgtg gggctggtgg tttgccagtt ggaacttcag gtaaagggat
    22381 gctcatgttg tcaggaggga ttgactcacc tgtagcaggt tatcttgctc ttaagcgtgg
    22441 ggtggatatc gaggcagttc actttgctag tccaccatat actagtcctg gtgccctcaa
    22501 gaaagcgcag gacttgactc gtaaattgac caagtttggc ggaaatatcc agtttatcga
    22561 ggtgcctttc acagagattc aagaggaaat caaagccaaa gcgccagaag cttatttgat
    22621 gactctaact cgtcgcttta tgatgcggat tactgaccgt attcgtgagg tacgaaatgg
    22681 tttggttatc atcaatgggg aaagtctagg tcaagtagcc agccaaaccc ttgaaagtat
    22741 gaaggctatc aatgctgtta ccaacactcc catcattcgt cctgtggtta ccatggacaa
    22801 gttggaaatc attgacatcg cccaggaaat cgataccttt gacatttcaa tccaaccgtt
    22861 tgaagactgt tgtaccattt ttgcaccaga tcgtccaaaa acaaatccta aaattaagaa
    22921 tgcggagcag tacgaagcgc gtatggatgt tgaaggcttg gttgagcgag cagtggctgg
    22981 aatcatgatt actgaaatca cacctcaagc cgaaaaagat gaagttgatg acttgattga
    23041 caatctgctc taattcagaa aatccaaaag aatagcgaaa atcagtaaaa aaagttagtt
    23101 ttttctctaa aaacaggtaa aaaactaact ttttttattt ttatgatata atgatataaa
    23161 attttgaata tagagagttt tctgacaatg aatcaatcct acttttatct aaaaatgaaa
    23221 gaacacaaac tcaaggttcc ttatacaggt aaggagcgcc gtgtacgtat tcttcttcct
    23281 aaagattatg agaaagatac agaccgttcc tatcctgttg tatactttca tgacgggcaa
    23341 aatgtttttt atagcaaaga gtctttcatt ggatattcat ggaagattat cccagctatc
    23401 aaacgaaatc cggatatcag tcgcatgatt gtcgttgcta ttgacaatga tggtatgggg
    23461 cgaatgaatg agtatgcggc ttggaagttc caagaatctc ctatcccaga gcagcagttt
    23521 ggtggtaagg gtgtggagta tgctgagttt gtcatggagg tggtcaagcc ttttatcgat
    23581 gagacctatc gtacaaaagc agactgccag catacggcta tgattggttc ctcactagga
    23641 ggcaatatta cccagtttat cggtttggaa taccaagacc aaattggttg cttgggcgtt
    23701 ttttcatctg caaactggct ccaccaagaa gcctttaacc gctatatcga gtgccagaaa
    23761 ctatcgcctg accagcgcat cttcatctat gtaggaacag aagaagcaga tgatacagac
    23821 aagaccttga tggatggcaa tatcaaacaa gcctatatcg actcgtcgct ttgctattac
    23881 catgatttga tagcaggggg agtacatctg gataatcttg tgctaaaagt tcagtctggt
    23941 gccatccata gtgaaatccc ttggtcagaa aatctaccag attgtctgag attttttgca
    24001 gaaaaatggt aagttaagaa aggaaaaaac gaaatgcata ttgaacatct tagccactgg
    24061 agtggtcatc ctaaccgtga aatgtacctt aaccgttatg gacatggtgg gattccagtt
    24121 gtggtctttg cttcatcagg tggtagtcac aacgaatact atgattttgg catgattgat
    24181 gcctgtgctt cctttatcga ggaaggcctt gtccagttct ttaccctatc tagtttggat
    24241 agtgagagct ggttggctac ttggaaaaat gctcatgacc aagcggaaat gcaccgtgcc
    24301 tacgaacgtt atgtgattga ggaggccatt cttttatcaa gcacaagaca ggttagtttg
    24361 atggcatgat gacgacaggt tgctctatgg gagcctatca tgcactcaat ttcttcctcc
    24421 agcatccaga tgtctttacc aaagtgattg ctctcagtgg tgtttacgac gcacgtttct
    24481 ttgtcggtga ttactacaac gatgatgcta tttaccaaaa ctcgccagta gattatattt
    24541 ggaaccaaaa cgatggctgg tttattgacc gttaccgtca ggcagagatt gtgctgtgta
    24601 cggggcttgg agcctgagaa caagatggtt taccatcctt ttacaagctc aaagaagcct
    24661 ttgaccagaa acaaattcca gcctggtttg ctgaatgggg acatgatgtc gcccacgact
    24721 gggaatggtg gcgtaaacaa atgccttatt tcctcggtaa tctctattta taaaaggagt
    24781 tacctatgaa ttaccttgtt atttctccct actatccaca aaactttcaa cagtttacca
    24841 tcgaactagc taataaaggc atcacagtct tgggaattgg tcaagagtct tacgagcaat
    24901 tggatgagcc cttgcgcaat agcttgaccg agtattttcg tgttgataat cttgagaaca
    24961 tagatgaagt caaacgtgca gttgcttttc tcttttataa acatggtcca attgaccgca
    25021 tcgagtctca caatgaatac tggcttgagc tagacgcaac actcagagaa caattcaatg
    25081 tttttggtgc caaaccagag gatctcaaaa agacgaaata taagtctgaa atgaagaaac
    25141 ttttcaaaaa agcaggtgtt cctgtggtac ctggagctgt tatcaagacg gaagcagatg
    25201 ttgatcaagc agtgaaagaa atcggtcttc caatgattgc caaacctgat aatggagtgg
    25261 gagcagccgc aacctttaaa cttgagacag aagacgatat caatcacttc aagcaagaat
    25321 gggaccattc aaccctttat ttctttgaaa aatttgtcac ttccagcgaa atctgtacct
    25381 ttgacgggct cgtggacaag gatggaaaga ttgtcttctc aacaaccttt gactacgcct
    25441 atacaccgct tgacctcatg atttataaga tggacaattc ttattatgtg ctcaaggata
    25501 tggatcctaa actgcgcaag tatggggaag caattgtcaa agaatttggt atgaaagaac
    25561 ggtttttcca tattgagttc ttccgtgagg gggacgatta tattaccatc gagtacaata
    25621 accgccctgc aggtggtttt accattgatg tttataactt tgctcattcc ttggaccttt
    25681 atcgtggcta tgcagctatt gtcgcaggag aggagttccc ggcgtcagac tttgaaactc
    25741 agtattgttt ggctacttct cgccgtgcaa atgctcacta tgtttattca gaagaggatt
    25801 tgcttgccaa atatagccag cagttcaagg ttaaaaaagt catgccagct gccttcgcgg
    25861 aacttcaagg agattacctg tatatgctga caactccgag tcgacaagaa atggatcaga
    25921 tgattgctga tttcggacaa cgtcaagaat aagaactatc ggattaagga aattaactcc
    25981 cttaatcctt ttgttttgtc tggtaaaaaa taagagcatc ctaacaaggt agctatcata
    26041 aaacttgttc gataactatt tgaagcagga ttaggtggct agaaattgaa ttttaacatt
    26101 tcaatttagt catagtattg tgttttcgta tccttaaatc agctaaaagg atccatgacg
    26161 acacctatac gatatagttt tcaagataca aaacaaatct att
//
LOCUS       DAVHBD010000030        25826 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000030 DAVHBD010000000
VERSION     DAVHBD010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.030"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(155..325)
                     /locus_tag="VVK04_001357"
                     /pseudo
     CDS             complement(155..325)
                     /locus_tag="VVK04_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(611..1066)
                     /locus_tag="VVK04_001358"
                     /pseudo
     CDS             complement(611..1066)
                     /locus_tag="VVK04_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1203..2087)
                     /locus_tag="VVK04_001359"
     CDS             complement(1203..2087)
                     /locus_tag="VVK04_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU3990008.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(2091..2477)
                     /locus_tag="VVK04_001360"
     CDS             complement(2091..2477)
                     /locus_tag="VVK04_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU3990009.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(2470..3813)
                     /locus_tag="VVK04_001361"
     CDS             complement(2470..3813)
                     /locus_tag="VVK04_001361"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU3990010.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(3895..4779)
                     /locus_tag="VVK04_001362"
     CDS             complement(3895..4779)
                     /locus_tag="VVK04_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3990011.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(4791..5408)
                     /gene="cysE"
                     /locus_tag="VVK04_001363"
     CDS             complement(4791..5408)
                     /gene="cysE"
                     /locus_tag="VVK04_001363"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU3990012.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(5424..7637)
                     /gene="pnp"
                     /locus_tag="VVK04_001364"
     CDS             complement(5424..7637)
                     /gene="pnp"
                     /locus_tag="VVK04_001364"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU3990013.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDYKPKKEFTETSKDSE"
     gene            complement(8322..9188)
                     /gene="metF"
                     /locus_tag="VVK04_001365"
     CDS             complement(8322..9188)
                     /gene="metF"
                     /locus_tag="VVK04_001365"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU3990014.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(9252..11501)
                     /gene="metE"
                     /locus_tag="VVK04_001366"
     CDS             complement(9252..11501)
                     /gene="metE"
                     /locus_tag="VVK04_001366"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU3990015.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATCIQLDEAALVKDLTAKEK
                     TLFLNLYNKLLTDKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFAEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(11762..12028)
                     /locus_tag="VVK04_001367"
     CDS             complement(11762..12028)
                     /locus_tag="VVK04_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3990016.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(12154..12601)
                     /locus_tag="VVK04_001368"
                     /pseudo
     CDS             complement(12154..12601)
                     /locus_tag="VVK04_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            12757..13758
                     /locus_tag="VVK04_001369"
     CDS             12757..13758
                     /locus_tag="VVK04_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU3990017.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTDSGIAPVTVIVKKSYDFYTKAETFHTTRFGTIVLHSRKQDIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(13826..16231)
                     /locus_tag="VVK04_001370"
     CDS             complement(13826..16231)
                     /locus_tag="VVK04_001370"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU3990018.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKTIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGV
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(16308..16817)
                     /locus_tag="VVK04_001371"
     CDS             complement(16308..16817)
                     /locus_tag="VVK04_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3990019.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(16817..17863)
                     /gene="pheS"
                     /locus_tag="VVK04_001372"
     CDS             complement(16817..17863)
                     /gene="pheS"
                     /locus_tag="VVK04_001372"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU3990020.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(18455..19870)
                     /locus_tag="VVK04_001373"
     CDS             complement(18455..19870)
                     /locus_tag="VVK04_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU3990021.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(19883..21721)
                     /locus_tag="VVK04_001374"
     CDS             complement(19883..21721)
                     /locus_tag="VVK04_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU3990022.1"
                     /translation="MSYKDTVQKILDAIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(21739..22578)
                     /locus_tag="VVK04_001375"
     CDS             complement(21739..22578)
                     /locus_tag="VVK04_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU3990023.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMTHIRRLTK
                     NLD"
     gene            complement(22878..25661)
                     /locus_tag="VVK04_001376"
                     /pseudo
     CDS             complement(22878..25661)
                     /locus_tag="VVK04_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         7601 a         5693 c         4569 g         7963 t
ORIGIN      
        1 caaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagatact atagtagatt
       61 gaaactagaa taatatacct ctacttctaa aatattgtta gaaatcgatt tgacttccct
      121 gatcgattcg tcctattctt atttcatttt aatataattg atagtggtcg ccccagccag
      181 ataccttatc tgctatccat ttaggaaccc ctaacttaag caatccccat aatcgtctcg
      241 atttcttctt ccattgcttc cagataatca ctcgtaggcg agtacgcaag cgctcatcta
      301 tgctagtgac tatacttttc atatttataa ttcattcctt tcgtttcact caaggcacaa
      361 cacagaatga aaaagtgttg tgatctttat tttgttttat aataatagtg agaaagccta
      421 tcactactac aaatcacggg gaggtgaata agtgagtggt acagccacta cctcgcatat
      481 tttgtcacat catttaacgg tacataataa gttgtaccat ctgaataagt tgctacaata
      541 tcatttgcat gctctccttc acctttagca aaggttggag ctcctgctgg atgattttta
      601 tttgcctctt tcaatttttc aataatggca ttttttctgt atcttttata ttatcaggat
      661 ttttcactaa gattttgtct ggatatgtcg gtttagcaga aacaattttt actgttactt
      721 cttttttatt cgaagcactt gtccagtttc cagcattatc tttagcattt aattttacag
      781 taattcctga actaggaact tcagtagcag gttgattatc aacattattc aactttaatt
      841 tcaaaagagc tgttgcatca gacgttttat caatcgttat atataatgat gaattgttat
      901 tataaacagt tccttcatat ttagctgttt gtgagctact tgaaacagaa ctgaaattat
      961 acccactacc tccctgatta tcttcaatgc ttacgtctaa atgaacttcc ccactattat
     1021 ttggcttagc aacaactgtt atagtaaaat aacataaaat ttacataaat agattaggga
     1081 aatcaaagca gcttctagga atgttttagc agtcacagtg tactttccca gcatcaagcc
     1141 actataactc tgcacataaa aatggagaag atggcaatcc tcttctccaa atattaactt
     1201 ctttacaaac caactatagt tgacaaagaa cctaaaatca attgataaca caaggtcagg
     1261 tcggtcaact ctttcaactg aagccctgtc aactcttccc atttatcaat cttgtattgg
     1321 agagaattgc ggtgcagata gagttgctgg gctgttttag tgagaacagc actattttcc
     1381 caaagagaga gaatgatttc ctgaatctga tcttgatcca aaatcatctg gtgtagacat
     1441 tccttgattg gcttcaagtc cacgagtctt tctcccatac tccaaagata gagctgagaa
     1501 aaagtatgaa caccttggtg accctgacgc caccatgtct tgaacaaatc ccgctcagct
     1561 ttgattaagt ctgatagggc ttgatgtccc gtctgagacc aaacctgacc caacatgata
     1621 gaaagacgaa gtccaaagtc atactcaacc gcttcaatcg tatcacttaa aatatctctt
     1681 acagaagtgt atttgtcttg ttgaagcacg aaaacataat cctgagctcc gacctgtagc
     1741 actgtctgac aattcggaaa aagagtccgc atcatatcta gccaagaagc cagattttcc
     1801 tgctgaaaat aagaaagatg gcaataaacc aactgaatct ttttaaaaac ttgcggtgcc
     1861 tgtcccttgc cctcaaccag ataggaatac caagggttta gcgaacgagc ctgctcctgc
     1921 tgggtcaaaa gggcaaccaa ctgcttttca cgctcgctga gcccagcttc ctccagcaaa
     1981 atccactgct gagaagctaa agggagcgtg agatagccct ctttctctac tggttggtct
     2041 gaaatccgag cctcaggaaa ccagtcttgt agttcttttg ccctcatgtt ctagccctcc
     2101 actttttgga tgcaccatga aaccaaactc tcaagacgtt ccagattctc agtcatatgg
     2161 agatagccca taaccgcttc aaatcccgtg gacatacgat aagtcacgac atctgcattt
     2221 ttagcctttg tgtggctatt ggtattgcgg ccacgtttgt agatttcttc ttctttttcc
     2281 gttaggacct gctcctccaa catgagagca atcaggcgag cctgagcctt ggctgacacg
     2341 tacttagttg cttcttgatg gagtttattg ggtttggtca tacctttgag gatgaggtga
     2401 cggcgaatat acatagaata caccgcatcc ccctcaaagg ctagcgcaat cccgttaatg
     2461 agattgacat caatcacgtg tccacctcac tccatccttg gtatcaagga gcttaattcc
     2521 ttgagtaacc aattggtcac ggatttggtc tgctgtcgca aagtcacgat tggcacgcgc
     2581 ctcttggcgt ttttgaatca agtcttcaat ctctgcatcc aaaacttcct caacaaagac
     2641 aattccaaaa atttctaaca tatctgcaag agcttgcttg acacttgcat catagttccc
     2701 tgagttgatc catttggcca tttcaaagac aactgtgata ccgttggcag cattaaaatc
     2761 ttcatccata gctgctacaa acttatcttt aaagttttgt aactcttggg catccacatt
     2821 tcctgtaaat ggttgttcgt aagtattctt gagatacttg agattggtct cggcatcgcg
     2881 aactgccttt tccgtgaagt tgataggctt acggtagtgc tgggtcgcaa agaagaaacg
     2941 aagtacttgc ccatcaagag ttttaagggc atcgtgtacc gtaatgaagt tacccaagga
     3001 cttagacatt ttgacattgt cgatattgac aaagccattg tgcatccagt agttagcaaa
     3061 agccttgcct gttttagctt cagactgggc aatttcattg gtgtggtgtg gaaactctag
     3121 gtcagctcca ccaccgtgga tatcaatggt atcacctaaa atctctgtcg acatgactga
     3181 acactcaata tgccaacccg gacgtccagg tccccaagga ctatcccaag aaatctcacc
     3241 tggtttggaa gatttccata gagcaaagtc tacaggattt tccttacgag ccgtttcttc
     3301 atcggtacga cctgaagcac ctagctccaa atcttccaag gttttattag ccaatttagc
     3361 atagttgtgg gatttttcta cacggaaata gacatcccct tgactctcat aggcaaagcc
     3421 tttctcgatc aagtcttcca caaaacggat gatgtctgcc ataaactcca ctacacgcgg
     3481 atggcgagtc gcaggtttca cgcccaatgc cgtcacatcc tcacgaaagg cagcgatgta
     3541 cttatccgca acctcctgag gcgtgatacc ttcttccctg gcacggttga taatcttatc
     3601 atccacatct gtaaaattgg aaatataggc aaccttatac ccacggtact caaaatagcg
     3661 acgaatcgta tcaaaagcta ccgtcgaacg ggcgtttcct acgtggatat agttgtacac
     3721 cgttggccca caaacataca tcttgatctt gccgtcctca atcgggacaa attctcgcaa
     3781 atcacgagac atggtgtcat agattttaat cataaatcat aatcaggaaa gctgaaatcc
     3841 aagaacaatt agtttcatca ctaaaagttc aagtaaattt cagtccgaat atctctacac
     3901 ttcggaatcc cttgctcctt tctcattcag ataaaccacc tgagtctgtt tgacaaagcc
     3961 aattttttca tacaaacgtt tggcacctac attgctatct tccactgcaa tctgaaattc
     4021 cttgtcattt tgctcaatta gttggttgac gagggatttt gctaagtagc ttccatagcc
     4081 ttttccacgt tcaggttcca atattgctaa accgtagagg taattcgtat tagtcgataa
     4141 atcaaccgta caagttccaa taacctgacc agcttttaat aaaatatata gtcggctttc
     4201 tggatctttc agagcttcag cgacatatct atccacaact tctctcgatt catgttcctc
     4261 tgaaaatgcc tgaaatttta attgactaat ttgatcctga tacgaactat ctgctaacaa
     4321 aacttcaaga tgggaaacat ttgctaacgg ataaggtctt ctatccttac ctaaccaagt
     4381 ttctgtctct tcatcctcga ttagtcccca gttactggca aagtcaggat gattctctaa
     4441 aaaaatacgt tctgtctgaa aagtgactga ccgaatgggg aaagaagctg tttctctctc
     4501 aaaactagta aacaatgcac gcgcaatccc ctgacggcga tgacctggat gaaccagtat
     4561 cgtcacttct acatcttggt catctgcata gacagttaat aaaccaacaa gttcgccttt
     4621 ttcataataa aggaaaaagg cgggcatgtt tgggtcaaaa ttaagcatgt tagagagata
     4681 gggatcgcga taggtaccgt catagttttg gcaacagtta attacttttt tcgcctcaga
     4741 tagctcctct tggcttaact tgtttcttgc ttgaatcata taggtatcct ctacaaacca
     4801 gacgatctgt gactggcatc tttagcctgc tcgagtttat tgacataata ctctcgtttt
     4861 tcttcgactt cgtgaatgac aggctcatct ttcttaccat gaagacggac aatcttggcc
     4921 ggaataccga caaccgtcac gtcactaggt acatctgcta cgacaactgc tgcagcaccg
     4981 accttggcat tttcaccaat ttccacaggc ccgataactt gggcatgggc tgatatgagg
     5041 gctccctttc gtacagtcgg atggcgtttg ccacagtctt tccctgttcc cccgagagtc
     5101 actccgtgat agagaagaac gcctttttca acaatcgctg tctctccaat caccagacca
     5161 gaaccatggt caataaaaac acctgaatca atctgggctc ctggatgaat ctcaatctga
     5221 gtccaaaagc gccaaaactg actgtacata cgagctaata gtttgaagcc gtgcttccag
     5281 agaaaatgcg agagacggtg ggccgccaag gccttgacac ctggataagt cagcaaaacc
     5341 tccaaagtgg tgcgggccgc tggatcattt tcttttacaa tatcaatggt ttcgcgccac
     5401 caccccatac atttctcctt ttcttattct gaatcttttg atgtttctgt aaattctttc
     5461 ttaggtttgt aatccttttg atgacgtggg cggtgagggc gctcagactt ttcacctttt
     5521 tcatcatgct caggttttgg cggacgaggt agaagagcct tcatagaggc atcgatacgg
     5581 cctttttcat caattttgat aaccttaaca tcaacttcat ccccgatttc taccaaatcc
     5641 tctacacgat tggtacgagt ccaagccatc tcagagatat gaacaagggc atctgtctta
     5701 tcaaagaggt taacaaaggc accaaatttc tcgatacgaa cgactttagc acggtaaact
     5761 tcatccactt tggcttcacg aaccaaacca gcaataattt ctttggcacg gttaatagca
     5821 tcttggtcac tagagtagat agacacattt ccttcttcgt ctatatcaat cttaacacct
     5881 gtttcagcga taatcttgtc gatggtttct ccacccttac cgatgacaat cttaatcttg
     5941 tccacatcaa tcttgatcgt atcaattttc ggagcagttg gagccaattc tggacgaact
     6001 tctggaatgg ttgcttcaat gacatcaagg atttcaaaac gcgctttctt ggcttgagca
     6061 agagcctccg tcaagatttc tgcagtaatc ccttgaatct tgatatccat ttgaagggct
     6121 gtaatcccat cacgagtacc tgcaaccttg aagtccatat ctccaaagtg atcttccaaa
     6181 ccttggatat ctgtcaatac tgtgtagtta tttccatctg agataagtcc catagcaata
     6241 ccagctactg gcgccttgat tggcacacca ccagccataa gggcaagagt tcccgcacag
     6301 atagaagctt gagatgaaga accgtttgat tccaaaactt ctgctactag acggatagcg
     6361 tatgggaatt cttccaagct tggcaagact tgagcaagag cacgctcacc aagggcaccg
     6421 tgaccgattt cacgacgacc tggcgcaccg taacgacctg tttcccctac agaatattga
     6481 gggaagttat agtggtgcat aaagcgtttc ttgtactctg gatccaaacc atcaatgatt
     6541 tgagtttctc ccatcggagc caaggtcaag actgaaagag cttgagtttg cccacgagta
     6601 aagagacctg aaccatgtac acgaggaagg aagtcaacaa ccgcatccaa aggacggatt
     6661 tcatcgacct tacgaccatc aggacgcacc ttgtcttctg taattaaacg tcgcacttct
     6721 gcgtgttcca tttgttccaa gatttcagcc acatcacgca taatacggtc aaattcttcg
     6781 tggttcgcat atttttcttc gtaaacggca gtcacttggt ctttcactgc ttgagttgca
     6841 gcttcacggg ccaatttctc ttctacttga actgcctttt ggaggtcact gttgtaggct
     6901 gcaatgattt cagcttgcaa ttcagcatcc acgtgaagca attccacttc tgctttttct
     6961 ttaccgacag cagcaacgat ttcttcttgg aaggcaatca attctttgac agcttcgtgc
     7021 cctttaagaa gcgcttccaa catgatttct tctgacaatt ctttggcacc agactctacc
     7081 atgttgatag cgtgcttggt tccagctact gtcaattcaa gaagagattg ctctgcttgt
     7141 tcttgacttg ggttgatgat gatttggcca tctacatatc ccacttgtac cccagcaatt
     7201 ggtccgtcaa atggaatatc tgaaatagac agtgccaaag atgaaccaaa catagcagcc
     7261 attggtgcag atgcattttc atcataagaa agcactgtat tgatgacttg gacttcatta
     7321 cggaaacctt ccgcaaacat aggacgaatc ggacggtcaa tcaaacgcgc tgtcaaggtc
     7381 gcatctgttg aaggacgtcc ttcacgtttc ataaagccac caggaaactt cccagccgca
     7441 tacatttttt cttcgtagtt gacttggagt gggaagaaat ccccagttgc cattttctta
     7501 gacataacgg cagcagtcaa gacagttgac tcaccgtaac gtacgacaac agagccattt
     7561 gcttgcttag caacctgacc agtttctaca attaactcac gacccgcaaa agtcgtttga
     7621 aacacttgtt ttgccatttt aatccccttt ggattgatga aattatacgc cttgcctaca
     7681 aagatcaaga taccaaggac gtcaaaagca aagtaaaaat aggaaactga cgaagtcttc
     7741 gatgaagaca agacagttta tcttttttac acagcttttc ggccgtgttc aattacacaa
     7801 gatattttgg acggttcggc ttgccgaaca tttctgtaga aaaataggaa ggtgacgtcg
     7861 cactcgacga gtgctaggaa gcttatcttt tttcctaaga aatgagacca aaattcaagt
     7921 catcaagata ccaagccgtc aagcaactca aaggaaaata ggaaatcgaa cgacggagcg
     7981 actgctccta gggagattta tctttttcca cagagttgta ggcaagttca gttttcaaga
     8041 tacatcatta gaaaggttta atactaaagt atctaaagct ttcacgctaa tcgctatcgg
     8101 gcgattagct aaatgcttta ctaactctct cgtcaaataa catcgatttg actcactcgt
     8161 gtcgttaaat cttacagttt aaatgcattg tattatttaa taccttcatc tttgtatcaa
     8221 gtacgtacag aatttatttt atcatatttt tcttaaaaag tgaggtcttt accattaaaa
     8281 aggaaccatt cccctcacct gagaagaatg gtttgctttt attatcctag agactggtga
     8341 ttaaacaagg catgggttgc ttgatggatg tattttgctg tatcagcatt attcatcgta
     8401 tagagatgca caccggcaac atcctgagtt accaagtcca cgatttggtc cactgcatag
     8461 gcaagtcctg ctgctctgag cgactcaggg tcatgctcat acttgtctaa gatggcttta
     8521 aatttgcgtg gaagatggat attctcacaa gtcttcaaga gtcggagagc ctgatttcga
     8581 ttcagaattg gcataattcc tgcatgaatg ggaacatcaa tcccagccaa gatgcacttg
     8641 tcctgaaaat catagaagcg ctcattgtca aagaagagct gagttacgag gctcgaacag
     8701 cctgcatcca ctttcttctt aagattttga atatctgaaa tctgatttgg cgaatctgga
     8761 tgcccttctg gatagcaagc tccaataata tcaaagtgag gggtttgttc cttgataaac
     8821 tcaatcaagt cggttgcata gcggaaatcc ttttgtggtt ccacgtctgg aataatatcc
     8881 ccacgaagag ccaagatttt ctgcacccca actttgtcca agtcagcaat agtttcagca
     8941 accttgtcct tagttagata aatagctggc aagtgggcaa tggtcggaat cgccaaatca
     9001 ttttggataa agtcagccaa acgaaccgtc gtttccttga tattaaattt attattgctg
     9061 gcagttacac tgataaaatg gggagccaac tcctgcatat actgcaaggc tgaaataatg
     9121 ttaccattac ccacggctgg gtttggaggg aacacttcaa atgagagtga cggtgtttgg
     9181 cgtgacatat gtaataacct tttctagttg atttcttttt gaacaaccac tgtatggaga
     9241 gaaatccaat cttacaattt ctcacgcgca gctttagctg cttcaacaag gcggatcaag
     9301 ctttcttttg tttctgggat accacgtgtt ttcaaaccac agtcagggtt gatccaaact
     9361 ttcttgcttg gcactttagc aaggatggct tcgattgtgt tgtcgatttc gccttcattt
     9421 ggtacacgag gtgagtggat atcgtaaacc ccaggtccca cttctgtttg gaagtttttc
     9481 gctttgagtt cgtccaagat ttcaaggttt gaacggctag cttcaaagga aataacgtct
     9541 gcatccatgt tatcgatagc tgggatgata tctgtaaatt ctgagtaaca catgtgagtg
     9601 tggatttgtg tgtctggcgc tactgttgag tgtaccaagc ggaaggcagg aatagcccag
     9661 tcaaggtagt cttcgtacca gtcgctacgg cggagtggca atttttcacg aagagcagcc
     9721 tcgtcgattt ggatgatttt cacaccagca gcttcaaggt caagtacttc atccttgata
     9781 gcaagggcga tttggagagt tgaatccttg atagagatgt cttcacgtgg gaatgaccag
     9841 ttaaggatgg taacaggtcc agtcaacata cctttaacag gtttgtttgt acgactttgt
     9901 gcatagctag accatttaac agtgataggg ttaagacgag tgacatcacc ccagatgatt
     9961 ggtggtttta ccccacgcat accgtatgat tgtacccatc catttttaga gaagaggtat
    10021 cctgacaagt tttgaccgaa gtactcaacc atgtcattac gctcaaattc accgtgaaca
    10081 aggacatcaa agtcaatatc ttcttgccac ttgatccatt cgtcaatcgt ttcagcaagg
    10141 aaagcgtcgt actctttttg agacaattca cctttacggt aagccaaacg tttggcacga
    10201 acttcttttg tttgagggaa tgaaccaatc gttgttgttg gaagagctgg aagtttgaaa
    10261 gcttcttctt ggatagcttc acgttctgca aaggctggca aacgagtgta gtctgcgtct
    10321 gtcaagccag cgatacgcgc acgaagttca gcattttcac caacacgctc agtcgcaaag
    10381 agttctttgt tggctgcaag agcttctgaa ccttgaccat tgcggatagc atccaagtca
    10441 cggatttcat ccaatttttc aactgcaaag gcaaagtggt tcaagagtgc tggttcaaat
    10501 tcttcattag cagttgtaaa tggcacatga agaagtgagc aagagcttgt caaaacgatg
    10561 ttttcagctg ggatttgctc aagaacagcc aagctctttt catagttgtt gcgccagatg
    10621 tttttaccat tgacaatacc tgcatagaga gtcttgtcag ctgggaagcc acctttaacg
    10681 agttcaagag ttttcttacc ttcagcaaag tcaagaccga tagcatctac tggtaagttt
    10741 acaaggtcag cgtatacgtc acgaacatca ccgaaataag tttgaagcaa gacttcaaga
    10801 ccttttttgt cagtcaagag tttgttgtaa aggttcaaga agagagtttt ttctttagct
    10861 gtcaagtctt ttacaagagc cgcttcatcc aattggatgc aagtcgcacc aagttcagcc
    10921 aatttagcaa aaacttcttg gtaagcagcc actaagctat ctacgaagtc gtctgctttc
    10981 acgccttctt caaagtctga caattgaagg aaagtgaagg gacctacaag aactggacga
    11041 gtgttcaatc caagttcttt tgcttcttgg aactcatcga aaatcttgtg accagctaat
    11101 ttcacttgag tgtctttttc aaatttagga acgatgtagt ggtagttagt gttgaaccat
    11161 ttcttcattg gaagggcgcg aacgtcccct ttttctccct ggtaaccacg tcccaaagcg
    11221 aagtagcgct caaggtcaga caagtccaag ttttgaactg aggcaggcac tacgttgaaa
    11281 aggaaagccg catctaggaa gttgtcatag tgagaaaagt catttgatgg gatttcagtg
    11341 atgccttttt ctttgacgat gttccagtgt ttagcacgca agtcttttgc ggctgcaagg
    11401 agttcttctt ctgagatttc ttttctaaag tatttttcag ttgtaaattt taattcacgg
    11461 aattcgccca aacgagggaa accgatgatt gtagttgaca tgatgtgtcc tccaaaattt
    11521 gttgttgaaa ctatcttaac agaaaagaaa gcgtctgtat aattgtaaaa aattaggctt
    11581 tgatatagtt tgaaactata tatctgtttc ggacaaaaga aaaagacttg aagcaaacgt
    11641 ctcaaatcct ttgtaattct tactttacag ctatattcca attagaatac taaaacatgt
    11701 tattagtaat tcttataagt gactatgacc tgttattaga aaagactata actgattcta
    11761 gtcaactttt tccctgttca agtgggacga ttgctagtgt ctttcctaaa ctggctagga
    11821 cttttaagac tgtatccaac tgaggactag tctttcctgt ctccatccta gctatgacag
    11881 gctggcttat tccactgact tcttccagct ttttctgact gattccttgt tcatacctag
    11941 cctcaatcaa ctcgctcatg atagccactc gcatatcact ttcaaggatt tcctccttgc
    12001 taaagagctc agatggacat ccttccaatt actcccaata gcactattct tcatcactta
    12061 accctctttc ttttacgtct atgtattttt aaaaaaatga gcgaattatg attcgataga
    12121 ttgaccagcg ggtttaaagt tggtgctagc ctatttctta agcgattttc cttttctagg
    12181 ataaagcaga tcctgcttgc ttaaccccaa ttttccacga tgaatccaat agtaaatggt
    12241 tgaaattccc acgttaaccc ctttagccat caccatcatt tcaggcgaaa atttttggtt
    12301 atgtatagtg gagaatcttt tcctttagtt ccttggtcaa gcttgatttc ttgaccgagc
    12361 gcttgcgatt gttttcataa gactgttgag cgtagtcggc agaataaacc tctttgaagc
    12421 gcccttttcc aagacatttt cggactgtcc cacgcttgat ttcagtgtgg atagtttgag
    12481 gagcttttcc aagtagagag gcaacttctc tatttgattt tccttctttt ttccatcttt
    12541 cgattaagcg acggctatcg attgtcaaat gtttaccttt tgtagtataa ttgtcttgca
    12601 tctctgtgcc ttttaatcat ttcaatctta aattggactt tttttacttg ggttgtactt
    12661 aatctataag gaagacaaga aaaagaatat caatcaagta aagtcacaaa gtcacattag
    12721 ctccgagcaa ccattgcaaa ttgaggtact cacacaatga ttaaaacatt tctctctgcc
    12781 ctttcggtca ttctctttgt tatccctatc ataacttatt ctttttttcc atcttctaat
    12841 cttaatattt ggctatctac cagacctatc ttggcacaga tttatgcctt ccccttagct
    12901 actgcaacta tggctgccat tttaagtttc gtattttttt ccctatcttt ttacaagaaa
    12961 aataaacaaa tacggtttta ctctggcatt ttgctcttat tatcgctcat attactatta
    13021 ttcggaacag ataaaaccct ttcttccgct tcaaataaga ctaaaacctt aaaattagta
    13081 acttggaacg tcgctaatca aatagaagca caacatattg agcgaatttt tagccatttt
    13141 gacgccgata tggctatatt ccctgaacta gctaccaata tcagaggtga gcaagaaaat
    13201 cagagaatca aactattgtt tcatcaagtt ggactttcta tggccaacta tgatattttt
    13261 acttctccac ctactgacag tggaatagct cctgtgactg tgattgtcaa gaaaagttac
    13321 gatttctata caaaagctga aacttttcat acaacacggt tcgggacaat tgtattacat
    13381 tcgagaaaac aagatatacc agatatcatt gccttgcata ctgctcctcc tctgccaggt
    13441 ttaatggaaa tctggaagca agacttaaac atcattcata atcaattggc ttcaaaatat
    13501 ccaaaggcta ttattgcagg tgattttaat gcaactatgc gtcatggagc acttgcaaaa
    13561 ataagctctc atagggacgc attaaatgca ctgccacctt ttgaaagagg aacttggaat
    13621 agccaaagtc caaaactttt taatgcaacg atagatcata ttttattgcc taaaaaccac
    13681 tactatgtta aagatttaga cattgtaagt tttcaaaact ctgatcatag atgtattttt
    13741 acagaaatca cattttaatt attttatata aaatcacccc tctagtgttc ataaactaga
    13801 gggggaattt gtatcctact atcgtttaac gcacttctgc attgactttt tcttcgagag
    13861 acgcttggat tttttccatg tagcgtgcga cttcttcgtc cgttaagctg tcttctggat
    13921 tttggaaggt caagctataa gccattgact tcataccaag tcccagtttt tcacctgaga
    13981 agacgtcaaa gagtttgata tctgtcaaac gtttcacgcc ggcagcttgg atagcatcta
    14041 caacttcttg gtgagtcact tctgccttga ggagaagggc aacgtcacgg ctgactgctg
    14101 ggaatttggt gatttccaca aatggaacag caggttggag cgccccttcg atggctgaaa
    14161 ggttaagctc agctacatac gtttctggaa tatcgtaagc cttggcagtg actggatgca
    14221 cttggccaag gaaaccaaga acttggtcac cgagtgaaat cacggctgta cgacctggat
    14281 gaaggctagc gatttcagat gttgctgtat aggttacttg gagtcccaaa cgagtaaata
    14341 gggcttcaag gattccctta gcatagaaga aatcaactgg aactgctgct gtttggaaat
    14401 ctttttcagc aaccaagcct gtcaaggcaa aggcaaagct gttgatctca tttggaagtt
    14461 cttcttttgg attacctgtt tgttcaaaga cttttccaat ctcataaagg gccaagtttt
    14521 tattcttacg agccacgttg taggcaacgg tatcaaggat ccctgaaatc atattttgac
    14581 ggaggactga acgatccaca gtcattggcc acatgagttc agtaaggtta ctcggttgag
    14641 ctgtgaactc aactgctttt tcaggagttg tcagagcata ggtgatgatt tctgtcaaac
    14701 ctgctccttc agcaatagta cgaacttgac ggcggagttt ttgtgtggct gtcaattcac
    14761 ctgctgtacc atcgtctttt ggtagactag ttggcaagcg gtcataacca tagatacgag
    14821 caatttcttc aaagaggtca gcttcgattg tgatatccca acgacgacgt gggactctga
    14881 ctgtaaagct gtctgcattt ccagaaagac caaagccaag acgacggaag acgtcttcta
    14941 catcagcata agacagctca gttccgagga cacggttaac atcagcaagg gttgaagaaa
    15001 cttctacatc tgaagtatca agctcacccg ctgaaacgat acccttacgc accgtcacac
    15061 ctgcaagttc cgcaatcagg ctagctgccg catcaagggc ttcattaact gttgccacat
    15121 taattccttt ttcaaagcga gaagatgact cagaacgaag gttcaggcga ccacttgtct
    15181 tacggatagt tttgccattg aaaacagcag cttcaaggac aacacgacta gatttttcag
    15241 agatttctgt tgcttgacca cccatgacac ctgcaagggc tactggcttg tctgcaacag
    15301 tgatgactag gtcattcacg tccaagtcac gttcttcacc gtccaaggtc accaattttt
    15361 caccagcacg cgcttcacgc acacggatgt cagtcccttc aaatgtgtcc aagtcaaagg
    15421 catgcattgg ttgaccaaaa tagagcagga tgtagtttgt cacgtccact acgttattga
    15481 tgggacggat tccttcgttc atgagaaggt tttgcaacca ttgtggactt ggtgcgatgg
    15541 tcacattgtc caagatacga gctgcatagt aaggcgcctt gtctgtctca atgctgacag
    15601 aaagggcatc tgccgcagct tcattagttt ctgttagagt aaatttttta aagttgactg
    15661 ccttgtcata gatggctgcc acttcgtgag ccactccaca catagaaagg gcatctgcac
    15721 ggtttggtgt gatggaaagt tcgatgattt catcatccaa gtctaggtaa gaaaagactt
    15781 cctcacctgg cacggcatct tcaggcaaga tttggatgcc atctgcgaat tccttaggca
    15841 caactgagtc agaaattccc aattcaccaa gtgaacagat cattccaagt gactccaaac
    15901 cacggatttt tccttttttg attttgtagt tatcagcgat acgagctcct ggaagagcca
    15961 ccatgacctt gatcccagca cgcacatttg gggcaccaca aacgatctga cgctcttctt
    16021 cttcgccaac gttaatctga caaacatgga ggtgagtctc tggcacatct tcgcaagaca
    16081 agacctcacc gacgacaatt tttgagagac cagcagctgg tgattcgaca ccctctacct
    16141 cgatccctgt agttgacatt ttttcagcca actcttgtga tggcacatca atgtccacca
    16201 attcttttaa ccatttataa gatacaagca taatttagtt ctccagaatg accattgcca
    16261 cactggttct tttcctttcc tatcatttca atagaagaat tctcttctta ccttaatttc
    16321 tttctcagta accaatccgt atctactttt tgaccaacca taaaatgatg ttggctaaat
    16381 ttttcaaaac catatcggtt ataaaacgct tgagcttttg tattatgctc ccaaacacct
    16441 agccaagccc aagaaaaact attttttgta gcaagttcaa gtgcgaattc aaacagttgc
    16501 ttacctagtc caaatccttg gaatttttgt agcacataga ggcgttgaat ttcaaaagcg
    16561 tcctctaatt ctctctcagt ttgagcactt ccccagttga ctttgagaaa accagctatc
    16621 tcctcctcat gcataatgaa ataggtttca gagtcaggat ttcccaactc agttgacaaa
    16681 gtttttagac tataagcctc ttcaaagtat tcctgtaact gctcttccgt attatcatac
    16741 gcaaaggttt cacgaaaggt ttgtttggca attttagcca acacctcaac atctgccatt
    16801 tctacttttc taatcattat ttaaactgtt ctgagaagcg gacatctcct tggtagaatc
    16861 cacggatatc gttgattcca taacggagca tagctacacg ctcttgtcca agaccaaagg
    16921 caaagccaga gtatacagtc gcatcgatac cactcatttc aaggacacgt gggtgaacca
    16981 taccggcccc cataatttcg atccaacctg ttttcttaca tacattacag ccttctccac
    17041 cacacttgaa gcaagaaaca tccacctcaa cagatggctc tgtgaatggg aagtaagatg
    17101 gacgcaaacg aatttgacgc tcttcaccaa acattttttg gacaatcaac tgaagcgttc
    17161 cttgaagatc agccatagag atatttttcc caactaccaa gccttcgatt tggtggaatt
    17221 ggtgactgtg ggtcgcatcg tccgtatcgc gacggaagac acgccctggc gagatcatct
    17281 tcaaaggacc tttagaaaaa tcatgggcat ccatagcgcg cgcctgaact ggagacgtgt
    17341 gggtacggag caagatttct tcagtgatat agaaagtatc ctgcatatca cgagctgggt
    17401 ggtcttttgg aaggttcata cgttcaaagt tatagtagtc ttgctccact tcaaaaccat
    17461 ccacgacttg ataacccata ccgatgaaga tatcttcgat ttcttcactg gtttgtgtca
    17521 aaacgtgacg gtgaccagtc gcaactggac gacctggaag cgtcacatcg atactctcgc
    17581 tagccagttg agccgcgact ttcttttctt ccaagagctt agctgtttct tcaaaagcag
    17641 ctgtcaagac atcacgagct tcattgacgt gtttcccgat gattggacgc atctcagcag
    17701 aaacatcttt catccctttg aggatttcag tgagcgaacc ctttttacca aggacagaga
    17761 cacgcaaatc ttgcatctct ttttcatttc cagcagtaat ctgcttcaag ctagccagcg
    17821 tttcttcgcg aagcgctttt aattgttctt caatagttga catatttcct ccatcagtct
    17881 ctcgtagata aaaagaaaac cacatgccaa aaactccact cggagcgttg acacgcggta
    17941 ccatccgttt tcatctgaca agtcagacct tcatttctaa atccatgcgc aagtgaattc
    18001 acccagcttt catatagaga gcttgcagtc acggctctcc tccctgatat acttcccttg
    18061 ggctactagt ctttcagatt cctattcaat tactacttag tttatcagat ttttaccatt
    18121 cttgcaagac ctatcttact tctgcttgtt agcttattct tatctaactt tatagcggat
    18181 tgaaataaga tgaaaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag
    18241 caattgtttc gtactatttt agattcagtc tgctatatat aaccaatcta tcctaagtta
    18301 actatttata atcggctctc tgtaacaaaa ttaaattaat taatccccct ataaaataaa
    18361 gaggtttaga atttgatgtc ttccaaacct ctttatttta tatttaatga gatgttgcct
    18421 taaccgtgat aatatctaat catcaataaa caaactattt gaataaggat tctccatttg
    18481 attcaatcac tcctttatac caagtaaagg acattttctt atatcgattg aatgtgccat
    18541 ttccatcatc atttcgatca acataaatga gaccgtacct cttagaaagc tgtgcagtgg
    18601 acatagaaac gcagtcaata catccccaag acgtatagcc cataatttcc acaccatctt
    18661 gtagagcttc agctacttgc aataaatgtt ctttcatata ctgaattcta taatcatctt
    18721 ggactgttaa gttattaaat tcatctttta ttagttgatc tttagcacct aatccgtttt
    18781 ccactataaa taatggaatt tgataacggt cataatatct atttaaaatt atacgtagtc
    18841 caattggatc aatttgccat ccccactcag aagactctaa ataaggattt actaagccac
    18901 caataatatt cccttctcct gaattatact gtgttggaag agcagattga gtcacactca
    18961 tgtaatagct aaaggataaa aaatctacgg tataattttt taataactct gcatcttcag
    19021 ctgcaaactc tatgttaatg tcatgttcct taaaatatct ttttgcataa ttcggataat
    19081 aacctctaac atgcacatct gaaaatagat aatttagatt ctcatactca tgagtcgccc
    19141 atacatcttt tggatttgga gtcattggat aagctggcat agctaatacc atacacccca
    19201 ccttaaactc tgaattaatc tcacgagcaa tttttgtaac caaactcgag gcgactaatt
    19261 catgatgtat agcttgatat aattcttgtt tcgaaagatt ctccttaggt atatctattc
    19321 ctccactagt aaatggtaat tccaaaacag agtttacttc gttaaatgta agccaatatt
    19381 taactttatc tttatacctt tctaaaactg ttcgagcaaa tttttcataa aaatgaatca
    19441 ttctcctatc aatccatcca tgatattttc ttgctaaata taatggagtc tcatagtgtg
    19501 aaagagttac aagtggttct atcccgtgag catgtagttc atcaaacaat tcatcataat
    19561 atttcaaccc agcttcgtta ggttcttcct catctccttt tggaaaaatt ctactccatg
    19621 caatagaagt acgaaaaaca ttaaagccca tttcagaaaa caaggatata tcttccttat
    19681 atttatgata aaaatcaata cctatcaatt ttaagttatc ttctgtagga ttttctgttg
    19741 cttctcctaa tccacctttg ggtaacacat cctgaactga taagccctta ccatcttcat
    19801 tatatgctcc ctctacttga ttagctgcaa cagctccacc ccaaagaaaa tcatctggaa
    19861 aaatggtcat aactttcctc cattataata ttaccagtaa ttccttagaa tgctcgattg
    19921 tctgattatt aggtaatact aatacatcta gaaaatcatt ggtattcgtt acaattactg
    19981 gtgtaactgt ttcgtagcct ttagtcttga ttaaattcaa gtccatttca aaaatcaact
    20041 gatttttgaa aactctgtct ccttcttcta catgactaat aaaaccttga ccttttagct
    20101 caacagtatc taatccaata tgaattagta actcaacacc ctcatcactc ttcaatccaa
    20161 ttgcgtgctt agtcggaaaa atatttgtaa ttttcccatc aaatggtgca taaaccttac
    20221 cttcacttgg aataatcgct actccgtctc caattagttt atctgaaaat gttttatcct
    20281 ggacatcgct taacggaatg atttctcctg atataggaga aaatatcatt tttttatttg
    20341 aaactccagc tttaacttct aaattgctag aactctcttc ttcatcgatt ccaaatatat
    20401 aagctaatac aaaggtaata acaaccgaaa taaccgccac aattaaagca tttacaatat
    20461 ttgatggtac atcagaataa ataaattgag gcaacgctat caaagatggg acagcaaata
    20521 gatacgcttt aacactagta agacctgcaa ataatcccgc taatccacca ccaatcatag
    20581 ctgcataaag cggtttttta tattttaaag tcacaccata taatgcaggt tcggtaatcc
    20641 ctgcaagtaa ggctgagaaa cctgctgcaa aagcaatttg ttttgtatta ttatttttac
    20701 tctttaatgc aacagccatc gaagcagccc cttgagctaa gtttgaccct aacattgctg
    20761 gaagaattaa tacgtctgga gtagcaatag atgccgccaa aaaaataggt gcaaaagccc
    20821 aatgcattcc agtcataaca ataaatggca taatagcgcc aagaatagct aatgtaagcc
    20881 atccagctac accatacatt tgcccaacta gatttgataa tccttcacca acaattactc
    20941 caataggtcc gactacaact aaggcaatac agcttgatac taataatact agcgtaggtt
    21001 gcaaaaaact cttagtaaca gctggtgtta atttagcaat cattttttca atatatttca
    21061 tcaaccaaac cataataaga attggaacga ctgacgaacc ataactagct ggtgtcacag
    21121 gtacaccaaa taaactaaga ggattccctg attgcaccat ttgaacaaaa tttggatgga
    21181 gaagtacacc tgctacagac atagctaatg tagatgttac ttttaatttt tgtgatgcag
    21241 aataagctaa taacagcggt aagaaataat atggagcatc cccaaaaaat gtcaaaaaag
    21301 caatagtctg agaatctgat tgcaatatac caagcattgg taaaataatt accaagactt
    21361 tcagcatacc tccccctaac attgctggaa tgattggagt catggaacca gcgatatact
    21421 caatgattct ttctaaaata ttccctttgt gcccttgaac aactgaatcg gattcaaaat
    21481 tgccaagttt aacgaattct ttataataat tagctacatc attaccaagt ataatttgat
    21541 attgtccatt ctttttcata atacctatta cacctggtat cttcttcaca tcatcatcat
    21601 tgactaaatt ttcatctttt aattctaatc ttaaacgtgt tacacaatgg gtaactctat
    21661 tgacattttt ttcacctcca attgcatcga ggattttttg taccgtatct ttataactca
    21721 tggtattctc ctattctatt aatctaaatt ttttgttaag cgacgaatat gagtcatcaa
    21781 ataaactaat tcactagaag tcagcaaata attgtactca gtttgtataa acattgccac
    21841 ctgttcacca cattcatatt ctctaggata tttatttttc attaatgcta acaagtcttc
    21901 atcatcatcg tcacaataag ttgtattttc aaccaagcga tgggcaaata attttatatg
    21961 agttatgaat ctataataat caatagaatc ttggttaaac tcagtacaat agaaatcttg
    22021 aatgattttc tcaattccca taattatttc agtgatttta tacgactctt gaaaattatt
    22081 ttctaaatta gcattaacaa aatgtagcgc tatgaatgca gcttcgtcaa ttggaagttc
    22141 aatacctaac tcttttttta ttatttgtaa agcccttttc ccaagttcaa attcttcttt
    22201 ataatatttc gatatttccc agcgtagggg attcgaaata ataatccctt ctttataacg
    22261 ttctatgctc gaagaaatat gatccgttaa attaatatag ataatttcat caaaattatt
    22321 acccaatgtt attttaccta ggttaattat tttttcggtg atgtacacca actccaaagg
    22381 aacgttaata aacatctctg taaaacgggt catattatct ctatttttga gaaaaaaact
    22441 tttctcaata tcaattggat ttactttatc tccagttttt cttccaaaag ctatgcccct
    22501 tccaaaaaga agaatatcga tatctttttt actttgcgca attacggcat tgtggtttag
    22561 tattcgtttt atgatcataa aatttccctt ttaaaataaa aggaacctac ttaaaaacat
    22621 caagaaactt cttccgatgt gattaaatag gttcctgctc acttgtatta gtgataacat
    22681 cctttcattt caatttttaa tggtgacatg aagcttaaat cattaataac tctgtaacca
    22741 ttttcatttt aagatatttc aatctatttg tcaagtactt atagaaattt ttttattttg
    22801 tgtgattcga atgtgataat gacaacagtc tcactaaaga aatgaaaatc atacatagaa
    22861 atttttaaaa attttctcta tcgtaaacct gccactagtt cagaagctat actagctgat
    22921 tccaaacgta atatggtcat ctcatctacc ttccctaata atggcattgc accataccaa
    22981 acaatagtct tattcaccaa aagaataggc gttactattt ttgattgagt aaaagacact
    23041 ttaattttct ggctcttcaa ctgatctagc catgctttat ttacaaccgt ctctggtata
    23101 catatctcaa tttgactaat cctaaattct tttagaaaat tcatcagttt tgtctggtgc
    23161 acataaggta aaataagcat acattcctgt ctttcccctg ctaagtcctc tctcaacacc
    23221 ttctcatatc tactatcaac ataaacgaat tgtttctcct caccctcaat ggcacgataa
    23281 tccatctttc gataagctac ttgtcgtttc tgaaacatct tttctaaata aggaacatga
    23341 atatccacat aatcgaaaat acgcaccaaa gacttatcct tgtagtttct atgaatccga
    23401 cctgcatact gaatcaaatt atttttccaa gaaaagggtg ctgccaagat aagcgtgtcc
    23461 aactgaggta agtcaaaacc ttcgccaatg tattttccag cagacaacaa aacaaaccct
    23521 ttatctaact gttctaacgt ctccagtaaa ctcgttctct ctcggacttt ggtttttccg
    23581 ctaataatgt aacagtcatc aacctctttc tctttcaata atttttcaaa gacatctatc
    23641 tgttgaattc gattaactaa aaccaagata ttccgtcctt ctgccacttg ggctagaata
    23701 tccttgagaa tcaactgatt cctcgctgag tcagtagcaa tccaatcact gagctgtata
    23761 aaattacttg ctttggtctt ttcaatttcc aaatgagcaa aagaagtgaa tcttaattgc
    23821 aattgccgtt taaaatccgt ttccctctta tcagcagtat ggagtatctc accaattctc
    23881 tgaaaaacaa taggctcatg accattctta cgctcaggcg tagccgtcaa accgtaaaga
    23941 tacttccctc taaactgagc aacaactttt tcaaacatca aggcagagac atgatgacac
    24001 tcatccacaa tcatcatctc atactcatcc aaaagacttt gactattttc caacttaaat
    24061 agagattgaa tcataacgac atcaaccagt ttactcagcc atttcttagt cccaccgtac
    24121 tgtccaacat agccgattac cttttcacga cctgatgccg tataacggat agcctcctcc
    24181 tcttcgaaag tcaaaaagca gtttaagcga tctagccatt ggtctaagag ttgcttatta
    24241 tggactagaa taattgtttt tgttttccgt tcagagataa gagcagcacc taaaacggtc
    24301 ttcccaaaac cagtctccgc atgaagtaaa ccattttctt tagaagtcat atctgacagg
    24361 gctaactctt gctcaaaagt gagttctccc ttaaattcca cgctaataga cctttgtacc
    24421 tttctcctat cttccacaac tacctgctta aatttatctt gcaatggata cagcaaacct
    24481 cttggcaacc ataaataatg atcggattct ccaaataaat acattctctc aggaatttga
    24541 taggttggct gtcgcatagc ctgctttaaa tataataaaa tgaaataata acaggacaaa
    24601 tcgatcagga aagtcaaatc gatttctaac aatgttttag aagcagaggt atactattct
    24661 agtttcaatc tactataaaa ttcgggatta gaaaaggaag ccatattttt caagaaaaaa
    24721 agtgccttgg atgtcacaga cgatttttca agttggatca tattggataa aacgaccttc
    24781 aactccttat ccaattcttg cttgcctaac tcctcttgga ttaacagtgc cactttagca
    24841 gttgaaatcc tctgaatttc ttgtagatac ctccattgat cttcataagg ctgaaaatgt
    24901 tcatccacaa agaccgttcg cccttgatga taagcttctc cttgaaaagg aagggaaatt
    24961 aaattatcaa attcaccttt aggaagaaca tcctgatttg gaaacatgcc atcaaaagaa
    25021 tcaaaggaca gttgcatact ttcctgcata gccaattcta atagtttctt tccaaacagg
    25081 cgagcctttt gactcagaat cgcttcctca aagaagaacc aaatatggag tccgtaaccc
    25141 gaacgagaaa tctctaaatg ggcttccatc tggcgttccc ttgctattct tcgaatggtt
    25201 aaaccagctt ctttccaatc tccttcatcc aaatccagta ccaaaaaata acagctatca
    25261 tctaagtgca taggaaagat accgatagct gcctccccac gaaaatgaga tttcaaaacg
    25321 gagttcgtca atgtctggaa actccgtttt tcaggtggca actgcttcca accataatca
    25381 taggaaggaa aatactgaat tttcccttgt tcattgataa aattcttagc ataaacatca
    25441 taacgtccag caaacacgga ggtaaacaat tgtaattttt cttgcgtcgt caagcgacta
    25501 ctttgaagtt ggaacatctc ctcgaactga gagcgttcca taacaaactg actcttgtct
    25561 ttaagacgtt tacacaagaa aaactcacta tccccattaa aagaagaaaa gacatcaagt
    25621 acttctacca caattccatc caaagacaca aaaacagcca taagagtcac ctccttgatt
    25681 cctataggct gattataaca agaatagctg aaattgtaca cgaaaataaa atcctaatag
    25741 tactcatttt gtatgtggct aatattccgt ctcgctccgg aatgtacgag gtaaatagag
    25801 tttaaacgag cagtctataa aattca
//
LOCUS       DAVHBD010000031        24600 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000031 DAVHBD010000000
VERSION     DAVHBD010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24600
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.031"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(39..1235)
                     /locus_tag="VVK04_001377"
     CDS             complement(39..1235)
                     /locus_tag="VVK04_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU3990024.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(1325..6235)
                     /locus_tag="VVK04_001378"
     CDS             complement(1325..6235)
                     /locus_tag="VVK04_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU3990025.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPG
                     ATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGHEVSFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDPSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPT
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            6528..8159
                     /locus_tag="VVK04_001379"
     CDS             6528..8159
                     /locus_tag="VVK04_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU3990026.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSDAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(8717..10324)
                     /locus_tag="VVK04_001380"
     CDS             complement(8717..10324)
                     /locus_tag="VVK04_001380"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU3990027.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(10714..11301)
                     /locus_tag="VVK04_001381"
     CDS             complement(10714..11301)
                     /locus_tag="VVK04_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU3990028.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(11429..11878)
                     /locus_tag="VVK04_001382"
     CDS             complement(11429..11878)
                     /locus_tag="VVK04_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3990029.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(11883..12272)
                     /locus_tag="VVK04_001383"
     CDS             complement(11883..12272)
                     /locus_tag="VVK04_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU3990030.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(12299..12925)
                     /locus_tag="VVK04_001384"
     CDS             complement(12299..12925)
                     /locus_tag="VVK04_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU3990031.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(12939..13502)
                     /locus_tag="VVK04_001385"
     CDS             complement(12939..13502)
                     /locus_tag="VVK04_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU3990032.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(13667..13901)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13955..14458)
                     /locus_tag="VVK04_001386"
     CDS             complement(13955..14458)
                     /locus_tag="VVK04_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU3990033.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(14651..15481)
                     /locus_tag="VVK04_001387"
     CDS             complement(14651..15481)
                     /locus_tag="VVK04_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU3990034.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(15466..17148)
                     /locus_tag="VVK04_001388"
     CDS             complement(15466..17148)
                     /locus_tag="VVK04_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990035.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGHTYGEFLIKGQAAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLLLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLRTELVKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(17250..17462)
                     /locus_tag="VVK04_001389"
     CDS             complement(17250..17462)
                     /locus_tag="VVK04_001389"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990036.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDETDEVSNHTYGKAKLMWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(17469..18017)
                     /locus_tag="VVK04_001390"
     CDS             complement(17469..18017)
                     /locus_tag="VVK04_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU3990037.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(18032..18880)
                     /locus_tag="VVK04_001391"
     CDS             complement(18032..18880)
                     /locus_tag="VVK04_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU3990038.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            19069..20418
                     /gene="trkA"
                     /locus_tag="VVK04_001392"
     CDS             19069..20418
                     /gene="trkA"
                     /locus_tag="VVK04_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU3990039.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIEREHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            20422..21861
                     /locus_tag="VVK04_001393"
     CDS             20422..21861
                     /locus_tag="VVK04_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU3990040.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(21987..22169)
                     /locus_tag="VVK04_001394"
     CDS             complement(21987..22169)
                     /locus_tag="VVK04_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEU3990041.1"
                     /translation="MGVYDLIILAPQVRSYYREMKVDAERLGIQIVATRGMEYIHLTK
                     SPSKSLQFVLEHYQAV"
     gene            complement(22223..22444)
                     /locus_tag="VVK04_001395"
     CDS             complement(22223..22444)
                     /locus_tag="VVK04_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IIBC"
                     /protein_id="HEU3990042.1"
                     /translation="MEVVLFSYCLNTRYLLQVIDIASSNDIILEEDTSEIMPGELDEI
                     KSKELKVLVLCAGSGTSAQLANAINKGLT"
     gene            22656..22826
                     /locus_tag="VVK04_001396"
     CDS             22656..22826
                     /locus_tag="VVK04_001396"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990043.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            23439..23723
                     /locus_tag="VVK04_001397"
     CDS             23439..23723
                     /locus_tag="VVK04_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990044.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            23716..23954
                     /locus_tag="VVK04_001398"
                     /pseudo
     CDS             23716..23954
                     /locus_tag="VVK04_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            24050..24268
                     /locus_tag="VVK04_001399"
     CDS             24050..24268
                     /locus_tag="VVK04_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990045.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLHEFY"
BASE COUNT         7196 a         5404 c         4494 g         7506 t
ORIGIN      
        1 actttcatcc ctctcttctt tgatttgttt ataaaatctt atttttctgt caaggctgca
       61 agtcctggaa gaaccttacc ttcaagaagt tccattgatg ctccaccacc cgtactaatc
      121 catgagaact tgtctgcacg gccaaggtta atcgctgcgg cagctgagtc accaccaccg
      181 atgattgatt taactcctgg ttgtttcacg atagcgtcca tcacaccgat tgtaccagct
      241 tggaaatctg ggttttcaaa tacacccata ggtccgttcc atacaactgt tttggcacca
      301 gtcaaagctt cgtcaaattt ggcgatagat tttggaccga tgtcaagacc aaggaagcct
      361 tcagaaactg cttcaccttc agtgtcacgc acttcagtgt aaccagcaaa tgcgttagct
      421 tcttttgagt caactggcaa gatcaattta ccatttgctt tttcaagaag agctttcgca
      481 acatccaatt tgtcttcttc tacaagtgag ttaccgattt cgataccttg tgctttgtag
      541 aatgtgtaag tcatcccacc accgataagg actttatcag ctttttcaag caagttttcg
      601 ataacaccga tcttgtctga aacttttgaa ccaccaagga tagccacgaa tggacgttct
      661 ggagtttcaa ctgcttcttg gatgtaggca atttcgtttt caagaaggaa accagcaact
      721 gctttttcaa cgtttgctga gataccaacg ttagatgcgt gtgcacggtg agctgtaccg
      781 aatgcatcgt ttacgaagat accatctcca agtgatgccc agtatttacc aagttcagga
      841 tcgtttttag attctttctt gccgtcaaca tcttcgtaac gagtgttttc aaccaagaga
      901 acttgtccat cttcaagagc gttgattgcc gcttccaatt cagcaccacg agtgacacct
      961 gggaaaacaa catcttgacc aagttttgct gccaagtcag ctgctacagg agcaagtgat
     1021 ttaccagctt tatcagcttc ttctttcaca cgtccaaggt gagagaaaag aattgcacgt
     1081 ccaccttgtt cgatgatgta cttaatagtt ggaagagctg ctgtgatacg gttatcgtta
     1141 gtgattacgc catctttcaa tggtacgttg aagtcaacac gaacgaggac ttttttacct
     1201 ttcaagtcaa cgtctttaac agtaagtttt gccatgttac aaaaactcct ttatttattt
     1261 tattcgaaac tattatatca cactttggaa atataaggaa agatttcaca agatttttcg
     1321 atatttaatc tttatcttct cttttccgtc tcaaggtcaa ggctaaacta gcaagaccaa
     1381 ggctggctaa gcctgctatt agggcttcat tagcatcagc tgttcctgta tttggcaatt
     1441 gtttgcttgc ttcttctgat ttaactgctg tattttgagc tggtttttcc tgtgtagcta
     1501 ctactgctgg tactgttttt acttttgttc caatttcaac aatttctgga atcgcttctt
     1561 ggatgacttc tgttgaacga agacgacgct gaccgttttc atcaacttca aagacatgtc
     1621 ttaacagtcc atctcgtccc tgtatgatga ctcgttgttc cccaactagc atctcagcat
     1681 tttcatgctc ttgacgatga aaggcaacct tttcctcttg aacttccaat ttaggagcct
     1741 tttgttgatc agaagtcggt tgataagtag gttttggaag gactgtgttt tgtggtgctg
     1801 gtttagcagg ttgtggtttt tcagcagatt cataaacaaa ggcataatga gtaaagtgag
     1861 gtgctgtaaa gataacatga ctatccgttt gttcaaaagc caattctact gcctctttgc
     1921 cttcaggtaa gaaaaatact ttcttaactt tcttatcttt ttcaattggg attttcacaa
     1981 tagaagcata agagggatca acatcttgac ctttttcatc caaaccttct atttcaaaga
     2041 catgagcatc ttctccagca aagtatttct tctcttcagc acttgcttga acacgctcta
     2101 ctttcaaacc cttgatgaca gtcttctctt tatttgagaa gtgtacttca acacctgttt
     2161 tactatcaga aaagactgct ggcttgtctt ctttcaataa agcaaccaga tcttttagac
     2221 tctgtttcgc tgttgtaagc tcttctggac tcaaatctac tttttcaacc aaggccttgt
     2281 ttttctcaag aagcggagct agggcagaac ctgaaggatg gtttggtttg gcagccaaga
     2341 gttcttgaac ctcacctgtt aagcgatcaa gctctgtctt ttcttccgta aatttctctt
     2401 gaccattcag agctttatga gcttctgtca atttattaag tcggtcattg acttgatctt
     2461 gggtgctagt ttcatggtct ttcaacactt gttcggccgc ttcaattgct ttcaagaagg
     2521 cttcttttac ttctgatgaa gcaaagttat agaccacctt gttcttagca gcttcaactt
     2581 ctgctaattt ttgtttgagg tactcatcgt tcaatgctgc ttttggagat accaaaacat
     2641 caaagctaac ttcatggcct tggtaatgaa gcgtcaaggt ttgacgacca gtcttttgag
     2701 catcgtaacc agaaatttca actccctcat cagtaaagga atgttcttcc atggtgtcat
     2761 tgctataagc cactgcaaag cgtccttcag acaagtctaa gctatcacca actaggtaat
     2821 cttttttcgg ttcctgactt acttcaattc ccaaaatagt tttcggactt gcttcgtctt
     2881 ggccagtgac agtcactgac aaattagcat ttaccggttg tcccaaatat tggagagtaa
     2941 gattctgttc tcccttatga tgcgtatcaa aacctgatac tgatacacct gcgtgagtta
     3001 ggcgaatgag ttcgtcctca gttcctcctt catactgaac tcgaagaaca ccacctctaa
     3061 ggtccaaatc ctccccttcg gcgtagcttg ttttcttagg tcctgtttct aggctgactg
     3121 acttgattct tctgtcatct tttggaacgg aaactgctag gacattacta atttccttgc
     3181 ctggcaactg ggtacgataa taaagaagac cagattgatt tgtcaaatcc aatggtgcac
     3241 ttgctaggtc tcctccaact tcgctcttca aggttgcgag cggagtttga gaatttggat
     3301 tatcataaac ggtaatagtt gctccagccg gtacatctgc aaagccaact tgtaccttgt
     3361 tattgcctag agaacgggct gcagccttgg ccatcggaat attgacactc tcagtatcaa
     3421 gcttttcata cattttccag ttatagatac gaatagcctt ccatggagtt ccattgtcag
     3481 aagtgacaac attcaagcgc cagtcttgag cagtgattgg tttatcaaga gtgatatctg
     3541 tcacgtgtgc tttgttacca cggacttcct tagctagctt ccactcacca tctgcatctt
     3601 tataataaag gtcaaagtct ttagtgttca tcaagccatc gttaacagac tcaccaccag
     3661 ctcctgcatg atccatgacc catctaacaa cggtacgtgg cttggtcaaa cgaatatcca
     3721 cactaccact caactgagct gaagaccatt tatctgacaa gctagtaatg gtaccgttca
     3781 acataccttc aataccttct ccaccttcag tcttagggaa agtactatca ataactgttg
     3841 cacctggaac gatattttca gctagtggtt ttggtaggct ggtatctttt acagtcatac
     3901 cccaatcaaa ggttgtggtt gcagcttctg aacgaactcc atttttaccg actgctacaa
     3961 ccttcagttc ttgagttgta ccctgagcac ttgctgagcg gctaactttt ggtagataaa
     4021 tagttgtaga agatgagcca gttagtaatt tccagctgtc tccatctttt tcataaactt
     4081 catagaaatc tgcatccttg ttgcctttaa attgcacaac tgcttccgct tcttgggcat
     4141 ttttaagcga ttgtttcact acagaaaagc ttgtcggcga ttgtggctct tggtgattgt
     4201 ccgagatagt taattgtcct aggttgaact gataatcttt tacagcacct tcatgctcga
     4261 aaaatagttt gactgcatag atggttttac ccgctagtga gctgagatca aattcttcat
     4321 ttgtccagtt gtcagaaagg gttagctctt tccatgcatc tgcatcatcg aatttgtagt
     4381 ctggagttgt agagaatgcc atataaactt tagaaccttt tcctcccttg tgggcaacac
     4441 gaagtttggt cttctcagtt acttctaact tagtagaata aagtctcaca tcctgatctg
     4501 tcttaccggc tacatcacca gagaatttaa gggaatttcc gccattatag gcatctgtaa
     4561 aatcatattc tgcacgaagt ttttcccctg ttgaagtctg ccaccagcgc catgttggaa
     4621 gaacacctga tactgaacga taattccact cagaatcctt agaaacctta ccatctacga
     4681 accatttttt accatgacct gtattaaaag aagtagtaaa agtattacct accgctggcg
     4741 tacggtccgc aactaggtta gcaataccat accaatcttt gtcacctggt ttttggccag
     4801 tggggtctcc ttgataacct gtaaagaaga tatcttcatt tttatgataa tcttcaccag
     4861 tttttcctaa acttgtaatg gtatctgggg caaataaacc aagagaaagg cgcaatttcc
     4921 cattttcgtc taaaatgtca ttccacttaa cctttgtctt gtaggaacca ccctgttgca
     4981 attccaaacc tgcaaataca tcataaggat tacgaccaat ccagttggca gttgcaatag
     5041 tgtaatcatt tttagcctta tcccagttaa agttagcaaa gaagttatct gccggaacct
     5101 tatctccttc tggttgcatg aattggtagt tgtattctcc caaaccatct tgatggtaac
     5161 gtccatagtt ataggtcatg gcatcatacc aagaatactt gattggatgg tttaccttag
     5221 cagcatattc cttgctatag agcataaact ggcgcatctt ttctccaaga ggtttaacca
     5281 aatctccagt tgtttcttgg ttgatgaaat agccatcata gccataatac tttgccatgt
     5341 ctaccaattt acgggcaatt gggaagctac catctgcgtc ttgcttcaaa gcttcagcaa
     5401 atctttcttg atctgcaata ctattagacc agttgaagaa gagtgtaccg tatacaggaa
     5461 ccccgttacg gtgacctgca tcaataacgt caggagttgg tacgagacct tcccagaaga
     5521 ccattgaatc tagatattgc caatagtcaa aagcataggc cttgaactct tctccaccaa
     5581 cagaagcatg gtcttttgct ttagaattgg tgtttgataa ggcttgaact tttgcttcct
     5641 tgctagcttt ttcattgact aaatgacctg tccgacgtga agcgaggaca acagatccgc
     5701 ggttaatagc atcatcttca cgagcacctg gttcccattt taacaattct tcccaagaat
     5761 taaatttgat ttcctttggt tttaatgttt tttctgtatt tttagggaca tctggctgga
     5821 cttctttttc agtcttatta gcttctgctg ctggcttaga ctcatcccct tggttagttg
     5881 cttcgggctt tgcttctgtt tccttgtcag acttaggttt tgcttctgca gatggtgttt
     5941 ctgcaaccac ctcacctgct ttttcctctg gtttagctgc gctagctgct tctgcctttt
     6001 ctagcttgtt ttctctagca tgttcccctt cattctgctt atcagcttca ttggtcgaat
     6061 gctcactctc tcctgaaaca agctctgtat tagctccgct attttcagga actgcagttt
     6121 cttcagccaa ggctggacca gcaaataaaa cagcaccaat catcagcgag caggctccta
     6181 ctgataactt acgaatactg taacgacaac gtctttcaaa aaatggattc ttcattttct
     6241 cctcctaaaa gattgatttt gttgttttaa agaaagcgct ttatattctg tagtttttta
     6301 tcaaactcta gaaccatgat aatcacattt ttatcctaaa acatttttag acaaaaaaca
     6361 ataactgttt gcacaaatct aaaataaggt taaaaactct taaaaataat acacttatca
     6421 attataattt tcttttacaa acttgacatt aacacttgtt agatttactt ttatccttta
     6481 aaatagaata ggagatgttc cgcgattatt tttcggagga aaaagaaatg tccattaatt
     6541 ggcaagaaat tttatttcac tttttaggtg gtctggggct attcttatat agcatcaaga
     6601 ccatgggaga cggtttgcaa caagctgctg gagatcgcct tcgtttttac attgacaaat
     6661 atactagtaa tcctttcttt ggagttctgg ttggtattgg gatgactgct ctaattcagt
     6721 ctagttctgg tgtaacagtt attacagtcg gcctggtcag tgccggtctc ttaaccttac
     6781 gtcaggctat cgggattgtc atgggtgcta atattgggac aactgtcaca tcctttctca
     6841 tcggttttaa attaggtaac tatgccctac ctatgctctt tatcggtgcc gtctgtctct
     6901 tttttacgaa aaatcggaca gtcaataata tcggacgcat cctctttggt gtcggtggta
     6961 tcttttttgc cctcaatctc atgagcgacg caatggctcc actcaaggat ttacaggtct
     7021 ttaaggacta tatgattgag ctaagtaaga atcctgtttt gggtgtcttt gtcggtactg
     7081 gcttgacctt gctaattcaa gcttcttcgg ctaccattgg gattttacaa aacctctacg
     7141 ccggcaatct aattgaccta cagggagctt tgccagttct atttggtgac aatatcggga
     7201 caaccattac agccatcatt gcctctttag gggctaatat tgcagctaaa cgggtagcag
     7261 gagctcatgt tgccttcaac gttatcggaa cagtcgtctg cgttattttt ctagttcctt
     7321 ttactgtcct gattcattgg tttgaagcta cgctaaatct agcaccggaa atgaccatcg
     7381 cctttgctca cggaaccttt aatattacca acaccattgt ccaatttcca tttatcggag
     7441 ctctggctta ctttgtaacc aagattattc ctggagagga cgaggttgtc aaatacgaac
     7501 ccttatatct tgatgaacat ttcatcaaac aggccccatc tatcgctcta ggaaatgcta
     7561 agaaagagct cttgcactta ggaaactacg ctgctaaagc ctttgacctt tcctataagt
     7621 acatcattga cttggatgaa aaagttgctg aaaaagggca taaaaccgaa gaagcaatta
     7681 acaccatcga tgagcaatta acacgttatc tcattgccct ttcaagcgaa gctctcagcc
     7741 aaaaagaaag tgaagtgctt accaatatcc ttgattcctc ccgtgatttg gaacggattg
     7801 gagaccacac ggaggctcta ctcaatctga ctgactatct tcaacggaaa aatgttgaat
     7861 tctctgatgc cgccttgaaa gaattagagg aagtttaccg ccaaactagt gactttatca
     7921 aagatgctct ggatagtgtg gaaaacaatg atattgaaaa agcacgcagt cttgtagaac
     7981 gtcatgaagc aatcaataag atagaacgtg ttctcagaaa aacccacatc aaacgcctca
     8041 acaaaggcga atgttcaaca caagctgggg tcaactttat cgacatcatc tcacactaca
     8101 ctcgtgtatc agaccacgct atgaaccttg ctgaaaaggt ttttgcagaa caaatctaag
     8161 aaccaagaag ctatccatca taattggatg gctttttact ttttcctaag caagactagg
     8221 ctgaatgaaa ctgaaagagt attctgcaga tatatagtat attgaaacta gaatagtaca
     8281 cctctatttc taaaacattg ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt
     8341 attatttcat tttattatag tggattaaat taaaaaagta tagtatattg aatctataac
     8401 agtacatctt gactgctaaa atatttctat aaattaattt gacttttctg atagagatgt
     8461 tcacatctta tttcaattca ctatacaatc cagttcctaa aactttgcta gaaattgatt
     8521 tggctttccg aattaatttg ttcaaatttt atttcatttc aatatactga taaatccatt
     8581 cactagcaca gggcaagaag gagtcgctat tgatttcaac ggtagcaggt acatacagag
     8641 gactcctacc tcagatatac tgcaatatca tcgtatgcaa aaacctctga gatttttctc
     8701 aaaggttctg attttgctaa ttgctgttct caaccgctgc agtaacaaag gcagtgtaga
     8761 gttcttctgg tcggtttgga cggcttgaca gttcagggtg atactgacaa gctacaaaga
     8821 atttattttc aggaatttcc acgatttcta ccaaacgatt gtctggagaa actcctgaaa
     8881 agacaaaacc tgctgcctca aactgctcac ggaaggcatt attaaactca taacggtgac
     8941 ggtgacggcg ttgcaccact tcttgattgt gataagcagc agcagcctta gagccacgtt
     9001 tcaacttaga cggataaagt cccaaacgaa gggttccacc catatcctca atatcaatct
     9061 gatcacgcat gatatcaatg atagggtatt ttgtttctgg tgcaagctct gcagaattgg
     9121 caccttcaag acctaaaacg tgacgagcaa actcgataca tgtcaactgc attcccaagc
     9181 agactcccaa cattggaaca tcattttcac gcgcatagcg gatggcttgg attttccctt
     9241 ctgtaccacg ttgaccaaaa ccacctggta cgatgatccc gtccgcatca gacaagagtt
     9301 ctgctacatt ctctgctgtc acatcattgg cattgaccca attgatttta acttctacat
     9361 cattgacata gccagagtgt ttcaaggctt cgaccactga gatataggca tcttgcaact
     9421 ccacatactt accaacaagg gaaatcttaa cttgtttctt gaggttcatg accttgtcca
     9481 ccatggctga ccattctgtc atatccgctg ctggtgcgtc taatttcaaa tgatcacaaa
     9541 caatttggtc catcccttgt gcctgcaagt tcagtggaat ttggtaaagg tgttcaacat
     9601 ccaacgattc gataacggct tctggtgcca catcacagaa ctgggccagt ttatttttaa
     9661 ttccttgacc agctggctct tctgtacgaa taaccaacat atttggttgg attcccaagc
     9721 cacgcaattc tttgacagag tgttgggttg gtttggtttt catttcacca gcagccttga
     9781 ggtaaggaag caaggttgta tggatataca tgacattatc cgcacccaca tctgccttca
     9841 tctgacgaag agcctctagg aatggcaagg actcgatatc tcctactgtt ccaccaacct
     9901 ctgtgataat gacatcagag tcggtcgtta gagcggcacg cttgattttt tctttcaaag
     9961 catctgtgat atgaggaatg acttgaacag ttgccccaag gtattctcca cggcgttctt
    10021 tacgaagaac ttcactgtaa attttcccag ttgtcacgtt ggaatatttg ttgagattga
    10081 tatcgatgaa acgttcatag tgacccaagt ccaaatctgt ctcagctccg tcatctgtca
    10141 caaaaacttc cccgtgctgg taaggactca tggttcccgg atcaatattg atataagggt
    10201 caaacttttg aatggttact ttgagaccac gatttttcaa gagacggcct agactcgctg
    10261 ccacaatccc tttcccaata gacgatacca caccaccagt tacaaaaata tatttcgtag
    10321 acatagattc ctctttctaa aatgctcaag gtcttgttaa ctacgagggg atatagaaaa
    10381 caagacccta ctaataagaa taatctggga cgactgcacc agattcacaa ctaatactct
    10441 tcgaaaatct cttcaaaccg cgtcaacgtc gccttgccgt agatatgtgt tcctgacttt
    10501 gtcagtctta tctacaacct caaaacagtg ttttgagcag cctacggcta gtttcctagc
    10561 ttgcactttg attttcattg agtataaaat acaagaagat aacttcttaa aaaaacaaaa
    10621 atagctccct aagaactagg gagccccgac ctctaaaaga ggtgcccaaa caatatgata
    10681 cctaaaaata ggataattgt caatagctaa ctcttattcc tcgctggttt cagcgtcgtc
    10741 atctgaaaac tcgtcgtcgt cttcgttgag atccacatct tctcccaagt catctggagc
    10801 gatttcgttg atttctgcat cataagcttc cacttcattt ttttcatcat ctggattttc
    10861 atcatcgtat gaaagagctg gatctgcttc gtatgcatct tcgtcttctg gatcatctgc
    10921 attgtagtca atggcatctg aatcaccatc cataaaggca ttgacacgtt ttttcttagc
    10981 ttttggtgct acttcatcgt cgtcattttc ttcaagagcg atgatttctt cgtcgatttc
    11041 gtccacacca taccatgaac gaagacccca tttgttgtcc ccaagtgaga tgaagctacc
    11101 gtcaaagttc aactctgtgt agaacaaagg caaagcttcg cggatatcgc tgtttgatgt
    11161 tccaaggtag ttttgaattt cgtttacaag atcgctaaaa tgcatctcat gatcgcgacc
    11221 acgaagttcc aagatagcac gcgctacctc aatcatagat agttcacttt tttcttgccc
    11281 agcaaatact tctaattcca aagcgtttct cctcatttat actactatcg ccagagcgaa
    11341 cagactctga cctcatttta tcatttactc tttattttac gataattttg cggaatagtc
    11401 aaaggttaag ggggagaaag tggcaggatt agactaattc caatataaaa ctccttcctt
    11461 tttctgttgc tccattttcc acaaatccaa gcgacttgaa acacctccta gaagcatgat
    11521 tgtaggtgta gatttccttg actctcaatt ctttccatcc ttttactcga gccaattcaa
    11581 tcaaagcact tagaatcttt tttccaagtc ctcgatgttg gtaagcggaa ttcccaatca
    11641 caatggggag attatcctga gatagtgtaa tatccccaat tggaaaccat tctcccttct
    11701 ccttgacttc aatccaaaaa agctcaccat gccgatccaa ataggaatac atggcttcca
    11761 aggtcgcttg actgtaagga agcttcaccc catctacgag gtaaaccaag ttcacatcct
    11821 gataccaagc aaaagcttcc tcacaatgat tgaccttata ataaggaaca aaacacaatg
    11881 cactaccttt tcaacaaaag agttgctgct tgattaaaac catcacacca gttataccat
    11941 tttgcttcat acccatcttg agctaggata cgatcttcta aatcaaaaac agagtaaatc
    12001 tttctttcct cgcaagcttg cgcatagaga tgatatagtt catcaccacc atctctatcc
    12061 cactcagcag aaatcgtatc ccgacctgcc aataaagcct gataagccct gtgatgccca
    12121 tctgtaatca gcaaacaatc tccaaaggca agaatactga ttggatcgac ttggattgtt
    12181 tctgccgact ggtaaagcat ctgaatatct tgcaacttct tttctgataa atatagttga
    12241 gtcggatgaa gatctgctat attgactttc atttctttct ctcaagggaa ttcgatactc
    12301 acttctgttt gcctttaaat cgccattgga agcggagctt gtcataaaag ggaaactcga
    12361 taaacaggac tcccaagccc acacagagac tggcaaggac gtctgatggg taatgaactc
    12421 ccagatagac tcttgatacc agcacactga ctaggtagag gccaaggacg atttgtacga
    12481 tttttctcca gacctgatct ttaatccgct gactaagaat aacaatcaaa gtccctacca
    12541 tcagcgttac agctagagaa tgcccacttg ggaaggaaaa tcccttctcc tccaccagat
    12601 gtaaaatagc tggtcgtggg cgctggtaga tatttttaaa ggtcacgatt aaaagacctg
    12661 ccaaagccag atttcccagc atgaagaaac tttctatctt ccatcgctta cgataaaaga
    12721 caaaagctgt aatgacaacc caagtgataa tcactgggat atcaatcaga cgtgtgaggg
    12781 ctcgaaaaag aatagtcaaa taatctggta agtctcctcg aatggcagtc tgaatcgatt
    12841 ggtcaaaatt gaccaacatt tcagggtaaa atttgaccat atagccaaga ataacgaaaa
    12901 gtaaaagggc aaaactgccc ttcattaaaa atgtttgttt atctttcata gtgttttaag
    12961 gttggtttca aaaggacgta caacaaccag aatgaaacgg aaaagattac accctcaatc
    13021 aagttaaaag gtaataccat ggtcattagg tagttggaaa gtcccaaaat ttttccaata
    13081 tcaaagttag caaacttagc gtacaaagga acagcataaa catagttgag aaccaacatg
    13141 gccaaggtta aaccaacagt tccagctaga gagcctagta ggaaacgaag ggttgtccgt
    13201 tcctttttcc aaatcaaagc aaatacgatg acaaaaactc ccaaagctac gatattcatc
    13261 ggcaaaccaa tgtaagtatt cactccttgg ctgttaagaa gcaatttcaa tagtgagcga
    13321 agcaagagca ctcctagagc agcaggcaaa tccatgacca ccagacccac aaggactggc
    13381 aagatactaa attcgatctt gaggaaagat gccgctggta aaagcggaaa gtcaaagtac
    13441 atcagcacaa atgagatggc tgatagaatt gcaatggtcg aaagtcgacg tgtgtttgtc
    13501 ataacaggtt cctccaattt tctataaaat cagaagaagt tggaaaggat tcctctatct
    13561 attctcactt tttatatccc aaaagttccc tcttactcta ttaaagaaaa acaaagcaag
    13621 tggttacaat ccggctataa atctatcaaa acagacaaag ctattctttc gtcttctccc
    13681 atccagacta tactgtcggt tgtggaatct caccacatca gcttgcgctc gcggacttct
    13741 ttaaagagaa ggaaatagag atttttcttt tagactaggc gacaagctgt aggcataact
    13801 tctggttagg caaagcttgt caacaaagta taaaaggaaa agatcatttc ctagttaaag
    13861 tcaccgccgg tcgggaatca caccctgccc tgaagactct tttatcataa caaaaaacgc
    13921 ttgcaagcgc aagcattttg ttcattttca ttttttattt caatttatcc acttcatagg
    13981 tatggacgag ttcaagacct gcaaagttct gctggcgaag agcctcatag acaatcatgc
    14041 agacggtatt agacacattg agactgcgga catgttcatc attcatggga atacgaagag
    14101 ccttctcagg atgttctcgc ataaaatctt caggtaagcc cttgtcttca cgtccaaaga
    14161 gaaaataatg gtcctcgtca gtcgataaat ccacctcaga atagattttt tccgcgaatt
    14221 tcgaaatcag atagagtttt cccttcatct gagacatgaa atcttctaag ctctcgtaaa
    14281 aataaatctc tagcttatcc cagtaatcca atccagcccg cttcatcttg cggtcatcaa
    14341 taggaaagcc cataggcttg atgatgtgga ggggagaatt ggtcgcagcg caagtacgcg
    14401 cgatattgcc tgtattttgt ggaatttgag gttcaaataa tacaatgtga tttgtcatga
    14461 cttgcttcct ttcaccattg caaaaaaata gccacactgc ccggagtcaa gctcagcaaa
    14521 cagcgtggtt aaggcatcgt taacttacct cacaacaggt ttgaagtaaa tcagcgaaac
    14581 tactttctta gtataacact ttcagaatca ttgtcaatag aaatgacttg attttttcaa
    14641 ttttttcaag ctatttccaa gggttgtaaa atcgtccctg attctgcaag ataagtagta
    14701 aactaactac taaaaacaag gttgccaaga gcaaggtaat atagtctcct tttttcaagg
    14761 cctgataact ataccatgtg cgttttttct ctttcccaaa gcggcgaagc tccatggcag
    14821 tcgcaatggt atcaatgcgt tctagcgagc taaaaatcaa gggcgtaata atgagcagat
    14881 tgcctttgat tcgttgcata agagaagctt tcttggataa ttccatccca cgcgcctcct
    14941 gagacatctt gatagtaaag aattcttcct gcaaatctgg aatatagcgc aaggtcaggc
    15001 tgacagaata agcaatctta tagggcacac caatttgatt taaactggaa gcaaactgac
    15061 taggatgggt tgtcatcaaa aagataatag ccagaggaat ggtgcaaaga tacttaatgg
    15121 ccaaatttag cagataaaag agctcctggc tggttagagt gtagacaccg attccctgcc
    15181 aaatcacact tctctctcca taaagtccaa ccccatactc gggagaaaag agatagacca
    15241 tcaaaacgtt taaaacggca aataccgtcg caaaaacggc tacaaaggaa acatctttaa
    15301 agcgaatttc tgataaatag aggagaaaga ctgaaaagat ggcaatcagc aagagcattc
    15361 tggtatcata gctaatcatg gccgccaatg ataccagaat gaaaaagaga agtttcccag
    15421 ctcctgacaa gcgatgaatc acagtatctc tatgctggta accgattaat ttagcttgca
    15481 tccctctctc ctttctttgt aaaatgccgt taaatccagt ggatccacat ctagtttctt
    15541 agccaagtta aagatggagg tttcttttag attggctttt actaacagct caggatcgct
    15601 caacagactg gctggaacag tatcggcaat caattctcca tccaccatga caaggacccg
    15661 gtctgaataa tccagcatca attgcatatc atgggtaatc atgacaatgg tatgcccttt
    15721 ttgatgtaac tcttcgagaa attccataat ctcagtatag ttcttctgat cttgacctgc
    15781 agtcggttca tctaggagga taatttcagc gcctaagacc aaaattgagg caatagtcac
    15841 acgttttttc tgaccaaatg acagggcaga aatgggccaa ttacggaatt catagagacc
    15901 acagattttc aaggtttcat agactctcgt ttcaatttcc tgctcgtcca cacctcgcaa
    15961 acggagtccc agagccacct catcaaaaat catattggtt gaaatcattt gattgggatt
    16021 ttgcagcaca tagcctactc gttccgcccg ctctgcaaca gaatctcctt ttatatcctg
    16081 tccttcccaa agatagcggc cttcagtctg gataaagcta cttatagcct tggctagagt
    16141 tgatttccct gctccatttt ttccgacaat agcaatcttt tcaccctttt taatatctaa
    16201 atgtagggat tttaaaatcg gtctatcatc ataagaaaaa gatacttcct ctagtctaaa
    16261 gagtgactgc aatgctgggg tttcttttac cagttccgtc cgcaactgaa cctgaccttt
    16321 tgagatagac aagttatcca gatctgctaa ttgttcttcc ttgactaaat ccacacccaa
    16381 ttgacggaga gtggtgagat aaaggggttc gcgaattcca ttttgggtca acaaatcagt
    16441 cgccagtaac tggtcagggc tcccattaaa aaggatacga ccatcgttta tcaagacaat
    16501 ccgatccaca gggcaatgca gaacatcctc caaacggtgc tcgataataa gggtcgtcgt
    16561 cccctcctcc ttatgaatct ggtcaatcaa ttcgataata tcctgacctg acttgggatc
    16621 aagattggcg agtggctcat caaacaagag aatcggactc tcatcaatca agacaccagc
    16681 tagactgact cgctgctttt gcccaccaga caaatcctga gggcgctgat ccagtaaaag
    16741 aagaaggtcc agcttttcag cccatttata aacacgacct ttcatctcat ctagggctgt
    16801 cacatcattt tccagagcaa acgccaaatc ttctgccaca gacaagccaa taaactgccc
    16861 atctgtatcc tgcaaaactg tgctaaccag atgagactta tcatagatgc tcatatcaaa
    16921 ggctgcttga ccctttatca aaaattctcc atatgtatga cccttgtaaa tattgggaat
    16981 aatcccattc aaacactgac ccaaggtaga tttacctgac ccagatggtc caacaattaa
    17041 gactttctct cccttgtaaa tggtcaagtc tatcccttgc aaggtcggtt cttgttgtgt
    17101 ttcataccgg aaagagaaat ccttccattc aattatagct tctttcatct tactctcttc
    17161 attcgcttct tagacttcta ttttatcata aatcaagccc ttcttgcagt ctcttctctt
    17221 aaaatcttag cgccaaaaag attcctatcc tagcttactt gcctaactaa tctataaaca
    17281 tcgaaaaaga ctagttgccc agccttcccc atcattttat actcttcgaa aatctcttca
    17341 aaccacatca gcttcgcctt gccgtaggta tggttactga cttcgtcagt ttcatctaca
    17401 acctcaaaac actgttttga gcaacctgcg gctaacttcc tagtttgctc tttgattttc
    17461 attgagtatt agtccttttt caaacttcct gcacgagttt gggttcctgc ataggcaagt
    17521 aagagaagag ttcctgcaat agctacagat acaccattgg caattcccgc aacaatccct
    17581 tgtgcaaata ctttttctgc cgcttcttga taaatcacaa catctccaag tggtgccaag
    17641 acaccccaaa caagggcatt tgcaagtagt tgaatgaggt taaaaataag aatatctttc
    17701 cagtcaaaaa caccattgat cacgcgaacg tactttctaa aaagtcccac aactaaacca
    17761 aagagtccgc tagcgataat ccaagtccac catagaccat aaccaacaag agagtccttg
    17821 attgcatgac caatcaaccc aacaagcaaa ccgataatcg gtccaaaaat aatagaaagt
    17881 agcgcttgta ccgcatactg aagctggatg cttgtatttg gaacaggggt tggaatgttg
    17941 atcatcccga tgacgacaaa gagggcagcg ccaattccga cagcaacaac ttgtttaatt
    18001 gtaaatttga tttccatact attctcctat tttatccttc tattttcttt atttcaatgg
    18061 tccaagatga accgacacct acattatagg ccttggcaaa ggaaccttgg ttgatagcca
    18121 aacctaaacg atagagagag ttgatgtaaa gaatgggttg cccaattctc acatctgcaa
    18181 atgatttgcc atagacaacc tgattttgat agaccagcat atcagcatga tagatggtca
    18241 cttcaaaacg atcaccaaat tctggttcca gcttgtaaaa ttcttcccgt gtgatagagg
    18301 tccaaagcga accgaaacgc acatccagaa tatcaatggc tcccttcacc agatgatctt
    18361 ctatgatggt cgctacgact ggaagctcta caatctgttc cacactgagc tctggcccta
    18421 cttcctcaaa agtaatgtga ccactggcca gtttagcacc agtataggca tagacatcac
    18481 gaccgtggaa ggtataagaa tgctctgtgt tttgacgcct attggccacc tcagaaatct
    18541 cacgaatggc tacaatgcca acgtgtttct tgataaagga aagcgtccca ttatctggcg
    18601 tgacaatgta ttgatttttt gcagtcttgg caactacact cttacgtttc gaaccgacac
    18661 ctggatcaac aaccgataca aacgtcgttc cctcaggcca gtaatccacc gtctgaaaga
    18721 gacgatagct cccctcaaaa atattataag gcgtgatatc gtgcgtcaag tgatgtattt
    18781 ttaaggttgg agactcttct aaagccactc caatcatagc cgataccgca ccatcaacca
    18841 gaccaaagtc tgattgtaat accagtaaat tattattcat tttatctcct tgtatatcct
    18901 ttatcatacc atatttcaga gaaagtcgct aatagctatt tcaattggtt agggtatagt
    18961 tttaacttat agcaaatttc ctactaaaaa ctctggttat tagctagtag gtgcattttt
    19021 tcttgaaaaa gggtatgata gttacatcat gaaaaagtag gttttattat gaaaattatc
    19081 cttgtcggag ggggaaaagt tggttttgcc ctctgtcgct ccttggttgc agaaaagcat
    19141 gatgttttgc tgattgagca agacgaagct gttctcaatc atattgtcag tcgctttgat
    19201 atcattggta tccttggtaa cggggccgat tttgccattc ttgagcaagc cagcgtccaa
    19261 gattgtgata tctttatcgc cctgactgag cacgatgaag tcaacatgat tgcagcagtt
    19321 ctagccaaga aaatgggagc taaagaaact atcgttcggg tgcggaaccc tgaatattct
    19381 aactcttatt tcaaggaaaa gaatattctc ggtttttctc ttatcgttaa tcctgagctc
    19441 ttggctgccc gcgctatcgc gaatatcatt gacttcccca acgccctgtc tgtcgaacgc
    19501 tttgctggtg gacgcgttag cctcatggaa tttgtcgtca agtccaccag cggtctttgc
    19561 caaatgccca tttctgattt tcgtaaaaaa tttggtaatg tcattgtctg tgcgatagag
    19621 agggagcatc aaattatcat tccaagcggt gacatgactg tacaggataa agatagaatc
    19681 tttgtcactg gtaaccgtgt cgatatgata ctcttccata attattttaa atcacgcgcc
    19741 gtgaagagcc ttctcatcgt tggggcaggt agaattgcct attatctact tggtattctc
    19801 aaagatagtc gtatcgatac aaaagtcatt gaaatcaatc ctgaaatcgc cagcttcttt
    19861 agcgagaaat tcccaaatct ctacatcgtt caaggagatg gaaccgcaaa agatatcctg
    19921 ctggaagaaa gtgctcaaca ctatgatgcc gttgcgactc taacaggtgt cgatgaggaa
    19981 aatctgatta catctatgtt ccttgacagg gtaggtgtac agaaaaatat tactaaggtc
    20041 aatcgtacca gtctcctcga gattatcaat gcgcctgatt tttcaagtat catcacacct
    20101 aaaagcatcg ctgtagatac gattatgcac tttattcgtg gtcgagttaa tgcccagtat
    20161 tcagaccttc aagccatgca ccatctagcc aatggccaaa tcgaaaccct gcaattccat
    20221 atcaaggaag ccaataaaat gactgccaaa cctctttctc aactgaaatt gaaaaaaggg
    20281 gttcttattg cagccattat tcgaaagggc aagactattt tcccaactgg ggaggatatg
    20341 ttggaagttg gagacaagct cctagtaaca accttgttgc caaacatcac caagatttat
    20401 gacttgattg cgaggtaaga aatgaataaa agtatgattc gttacctcct ttcaaagtta
    20461 cttttgattg aagctgttct cctcttggtt cctgtggcta tcgctgtcta ttaccgtgaa
    20521 tcgagccaag tctttacagc cctcttttcg accataggga ttctcgtatt gttaggcggt
    20581 tcagggagtt tacagaagcc aaaaaatcaa cggatttatg ccaaggaggg agtcttgatc
    20641 gttgccctct gttggatcct ttggtctttc tttggtggtc tcccctttgt cttttctggg
    20701 caaatcccca gccttattga tgcctttttt gaaattagtt ctgggtttac aactactgga
    20761 gcaagtattt tgaacgacat ttcggttctc agccgttccc tcctcttctg gcgaagtttt
    20821 acccacttga ttggagggat gggagtgctt gtttttgcac ttgctattat ggacaatgcc
    20881 aaaaatagtc acctagaagt aatgaaggct gaggttcctg gtcctgtctt tggtaaggtt
    20941 gtatccaaat taaaaaacac tgcccagatc ctctatctcc tttacatagc cctcttttcc
    21001 ctctttgtca tcatctatta tctagccggt atgcctctct acgatagttt tgtcattgct
    21061 atggggacag cgggaactgg aggatttacc gtctataacg atggaattgc ccactatggt
    21121 agctcactga ttacctatct ggtcagtatc ggagttctgg tttttggggt aaatttcaat
    21181 ctctactact acctcatgct ccgtcgcatc aaggccttct ttggagatga agagcttagg
    21241 gcttacttgg tcattgtact ggtttctaca ggcttgatta gcctcaacac cctctacctc
    21301 tacccagggt tttcaaagag ctttgaaatg accttcttcc aggtttccaa catcattaca
    21361 acaactggtt ttggatatgg agatattacc aactggcccc tcttctccca gtttatcctc
    21421 cttttcctca tggcaatcgg tggctctgct ggatcaactg caggtggact caagattatt
    21481 cgaggcctca tcctttcaaa aattgccaaa aaccaaattt tgtcaatcct atcgccccac
    21541 cgtgttttga ccctccatgt gaatcaaacg gtgattgata aagataccca gcataagatt
    21601 ctcaagtact ttgtcatcta tgctatgatt ttgctagcgc ttatctttat tgtcagccta
    21661 gatagcaatg attttctggt cgtgaccagc gctgtcttta gctgtttcaa taatatcggg
    21721 cctattctag gaaccacttc tagtttctca atctttagtc ccatctcaaa aattctccta
    21781 tcctttgcaa tgattgcagg gcgcttggag atttacccaa tcctccttct ctttatgaag
    21841 agaacttggt ctaagagata aaatacaaaa tccctctttt tacaattgtg aaagagggat
    21901 tcttatatta aaaaaggggg aacgttttta aatccaagcc tatctgtaag caaaatcctt
    21961 actcaaataa aagatggaaa aacttactac acagcttggt aatgctccaa tacaaattgt
    22021 aaggatttac ttggactctt tgttaaatga atatattcca ttcctctggt agcaactatc
    22081 tgaataccta atctttctgc atccaccttc atctctctat aataactccg aacttgtggg
    22141 gccagaataa ttaaatcata aacacccata atatcataat gagctccgta cgctcctgaa
    22201 ttcgcaatca ctctaacctc tgttaagtta gccccttgtt aattgcattg gctaattgcg
    22261 cacttgttcc agaccctgca caaagaacca gtactttcaa ctccttactt tttatttcat
    22321 ctaactcacc aggcattatt tcacttgtat cctcctctaa aataatatca tttgagcttg
    22381 caatatctat aacctgtagt aaatatctcg tatttagaca atatgaaaat aagacgactt
    22441 ccatatagga aaccgccttc tcgctatgtt gcatgaaact gtaaaagtgg atgaaattga
    22501 tagtgatagt caaatcaaga ggcatcataa ctctaaaaag tcacaatata taagttcatc
    22561 ctcggaaaaa tatcattcta attgttgaaa tggatatata aacaggggta ttaacattaa
    22621 atactcatga aacaacgaat acaggtatca aaactgtgac aaaacaagtc cctaaattta
    22681 ctaaagacac tgctcaactt tacacctgta aatggttgtt gtataataaa gttacaaaga
    22741 tgtacgacca cactgttgta aatcatagtg ttcgcgaata tattactgat agcatttcta
    22801 caaatacaat tgaagagact ggataggctt taaacgaaat atgtcagtgt tttggcattc
    22861 ctagtcttca tatcatttaa agaattgtat agacaaaatt tttttccaat acagacactc
    22921 gtaacaactg cttcattttt ctaccaacat atttaggaac aggataagat agaagaagat
    22981 taatccatag ctcagttcta taccaatcta agacaaataa gctaaaaaaa cgattgataa
    23041 taagcaaata gattccaaat tttctctatc tgctcatttt aataaacaat actagtgtaa
    23101 ctatccttcc agtcagaaac ttgtcaaatc acaccgaaaa ctcttctaaa atttatctcg
    23161 ttaggcaatc aagcaaaaac tcgacgatag tacaaacatt atcatacaga attgactgcc
    23221 taaattatat actttagtaa ggttttcgga taagaaaaaa ggttcatttt acatttctaa
    23281 acattctttt ctaagatgaa aaacagaatt tttcgattgt gatttaaagc aacaagaaga
    23341 ttttcagtat catcctatag atacgagcta attaagaaaa actacatttt tgaatataaa
    23401 ctacaataat ataaactaaa ttttatagga ggaagacaat ggattggtac gattatatga
    23461 tacaggcatc caaacaatca caattcaacg caagccattg gtttcgctat ttgcgaaaag
    23521 ttatttttga agactattct tatttaacaa accaagatgt agaaaagttg ctagactcca
    23581 aagaactaac ccgttttcaa aaaattagct tgaagtatgc ctttcaagag catactccaa
    23641 ctcataaata tgtgatttca ttaaataaac ctgctaagtt aaccaatgtt caaaaattga
    23701 tggagaaata caaacatgga taaaatgaaa ccggtcttcc aagccctaaa taagaaatta
    23761 attcaggaaa atctgacttt aacaattatg gttatgtctt agaatatcat ggtttacgtg
    23821 ccacacaaga tgttgatgct ttttatgacc aaaatcagaa aatcaatgaa attattgctc
    23881 gtgtaggaaa acagtttaat cttaacatcc acgaagagtt atggctcaac aatcatgttg
    23941 caaagcaaat atgaacaaac aacctccctt aagtttatgc gaatccttgt actcatttga
    24001 gaatctgacc gttttagtag tccctattga gtatgtgtta ggaatgaaga tgatgagtat
    24061 cagagagcag gatttgcaag atattggtgc aattattaaa tacaaaaact ttcattcacc
    24121 attcgatacc tttaaatatt taaaagacat gggatttgat actattgacc tctctgttct
    24181 attagaaggt tttagttatg cttatggtat ggattggtta gaaaaatttt ttaaagaaaa
    24241 tcaagataaa cttcacgaat tttattaaca gtatcaaaca agatgattgt caattagcca
    24301 gtcgtcttat ttttatgatg aaatgaaatg aaataaaatc ggaacaaatc acttagagaa
    24361 ttccagtcaa tttctagcac tgtttgagcc gtttcagcgg actatagtaa aatgaaataa
    24421 gaataggaca aatcgatcag gacagtcaaa tcgatttcta agaatgtttt agaagtaaag
    24481 gtgtactatt ctagtttcaa tctattatat ttcagattcg gtccactgtt ccttcccaaa
    24541 aacaggctct ataatatttg tagtgggtaa atccactata gatattatgg agcctatttt
//
LOCUS       DAVHBD010000032        24415 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000032 DAVHBD010000000
VERSION     DAVHBD010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.032"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(124..327)
                     /locus_tag="VVK04_001400"
     CDS             complement(124..327)
                     /locus_tag="VVK04_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3990046.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(320..1402)
                     /locus_tag="VVK04_001401"
     CDS             complement(320..1402)
                     /locus_tag="VVK04_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU3990047.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1528..2310)
                     /locus_tag="VVK04_001402"
     CDS             complement(1528..2310)
                     /locus_tag="VVK04_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU3990048.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2310..3653)
                     /locus_tag="VVK04_001403"
     CDS             complement(2310..3653)
                     /locus_tag="VVK04_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU3990049.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGVDSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3752..5068)
                     /locus_tag="VVK04_001404"
     CDS             complement(3752..5068)
                     /locus_tag="VVK04_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU3990050.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5261..6487
                     /locus_tag="VVK04_001405"
     CDS             5261..6487
                     /locus_tag="VVK04_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU3990051.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6686..8260
                     /locus_tag="VVK04_001406"
     CDS             6686..8260
                     /locus_tag="VVK04_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU3990052.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8524..9312
                     /gene="codY"
                     /locus_tag="VVK04_001407"
     CDS             8524..9312
                     /gene="codY"
                     /locus_tag="VVK04_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU3990053.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9312..9887
                     /locus_tag="VVK04_001408"
     CDS             9312..9887
                     /locus_tag="VVK04_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU3990054.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            9969..10054
                     /locus_tag="VVK04_001409"
     tRNA            9969..10054
                     /locus_tag="VVK04_001409"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10003..10005,aa:Leu,seq:aag)
     gene            10337..11467
                     /gene="ugpC"
                     /locus_tag="VVK04_001410"
     CDS             10337..11467
                     /gene="ugpC"
                     /locus_tag="VVK04_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU3990055.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11614..11760)
                     /locus_tag="VVK04_001411"
     CDS             complement(11614..11760)
                     /locus_tag="VVK04_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990056.1"
                     /translation="MEIKEQTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            11968..12726
                     /locus_tag="VVK04_001412"
     CDS             11968..12726
                     /locus_tag="VVK04_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU3990057.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12813..13325
                     /locus_tag="VVK04_001413"
     CDS             12813..13325
                     /locus_tag="VVK04_001413"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU3990058.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13507..14451
                     /locus_tag="VVK04_001414"
     CDS             13507..14451
                     /locus_tag="VVK04_001414"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU3990059.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            14460..15137
                     /locus_tag="VVK04_001415"
     CDS             14460..15137
                     /locus_tag="VVK04_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU3990060.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15235..15993
                     /locus_tag="VVK04_001416"
     CDS             15235..15993
                     /locus_tag="VVK04_001416"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU3990061.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16031..17536
                     /gene="lytC"
                     /locus_tag="VVK04_001417"
     CDS             16031..17536
                     /gene="lytC"
                     /locus_tag="VVK04_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU3990062.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18032..18550
                     /locus_tag="VVK04_001418"
     CDS             18032..18550
                     /locus_tag="VVK04_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU3990063.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            18680..19186
                     /locus_tag="VVK04_001419"
     CDS             18680..19186
                     /locus_tag="VVK04_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU3990064.1"
                     /translation="MTKKIVAIWAQDEEGVIGKKNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19186..19356
                     /locus_tag="VVK04_001420"
     CDS             19186..19356
                     /locus_tag="VVK04_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990065.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            19388..20620
                     /gene="clpX"
                     /locus_tag="VVK04_001421"
     CDS             19388..20620
                     /gene="clpX"
                     /locus_tag="VVK04_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU3990066.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            20629..21216
                     /locus_tag="VVK04_001422"
     CDS             20629..21216
                     /locus_tag="VVK04_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU3990067.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21227..21607
                     /locus_tag="VVK04_001423"
     CDS             21227..21607
                     /locus_tag="VVK04_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU3990068.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            21659..22549
                     /gene="rapZ"
                     /locus_tag="VVK04_001424"
     CDS             21659..22549
                     /gene="rapZ"
                     /locus_tag="VVK04_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU3990069.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKCLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22546..23523
                     /locus_tag="VVK04_001425"
     CDS             22546..23523
                     /locus_tag="VVK04_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU3990070.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIVDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23520..>24415
                     /gene="whiA"
                     /locus_tag="VVK04_001426"
     CDS             23520..>24415
                     /gene="whiA"
                     /locus_tag="VVK04_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU3990071.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINK"
BASE COUNT         7258 a         4487 c         5528 g         7142 t
ORIGIN      
        1 ttgtctaact tttggggggc agtacatatt caacacctga tactatgcgt tttattgtgg
       61 gaagattttc ctcattttct agtgaaattg aactttttct aacatctttt gatagatgac
      121 ttcttaatca attatcattt ccattgttgt ttcttggggt ttcatccctt gtctttgata
      181 aaagcggaga gcaccctcgt tatcattcca gacacttagg gttagattat tgcagccaat
      241 ttctttagca taatagcaga aaaatgacaa taaaatagcc cctagatatt ttgaaaggaa
      301 agcatagggg ctatatagtt taatcaaaat aaagcaaatc tttgctggtg cttgtaaaga
      361 ggtcgaagcc atccttggta acaacaccgc agtcttcaat acgaacaccg actttaccag
      421 ggatatagat acctggttca acagagaagc acatgccttc ttcgatgacc atgtcgtttc
      481 cttccatgat agatgggaat tcatggacat ccataccgat accatgcccg agacggtggt
      541 tgaagtactc accataacca gctttttcga tgacctcacg ggcagcgcgg tccacttcat
      601 gagcagtcac acctggcttg ataaagtcaa gagcagcttg ttgggcttca agagtcaagt
      661 tgtaaatatc tttcttgaat tggtctggtt tgccgacagc gactgtacga gtcatatctg
      721 acgcatagcc attgaccaga acacccaggt caaagaggag aagagcatca ttttcaacct
      781 tattagctgc tggaatgccg tgtggattcg cagcattatc accagtcaag accatggtat
      841 caaagctcat ttcataacct tcacgtttca tggcaaagtc gatttgtgcg atgatatctg
      901 tctcagtctt atcaagagaa atattgtcaa aaccaacatg aacagccttg tcagcataaa
      961 gacctgcaac catcattttt tgcacttcat cagctgattt gatgaggcgc atgcgttgga
     1021 tacgaggagt gaggttgtca aactcagcag tctcaaaaac tgttttcaaa ccatggtatt
     1081 tggtcaagat gagattgtca aactcaacag cgacacgttt gaagtcaagt tgtggaagag
     1141 catgtttgat tttttgccat ggattttcag aatcgacata gcccactact gggaaggaaa
     1201 cggtgctact tgcacgttct acttcaagag ctgggacaaa gaggagaggt tcctgatccg
     1261 ctaggacaaa gaggaacatt tggcgttcat ggggatcact gtaaaaacca gtgaggtaat
     1321 tgattgtgac ggggtcagat acgacagcga cgtctagttt ttctgattca agatatgtta
     1381 ggatttgttg taatttagac atatgctacc ttctttctac ccctctattt tggcaaaaaa
     1441 tgagagaaaa tgcaagggag aagggtaaaa gaagagacaa aaaactccga caagataacg
     1501 gagttctttg atatcatttt cctttgttta agaaaagtca gccttgcttt tgacgtcact
     1561 gtactcttca gcgatttctt ggctgagaat gtcctcatag gcagggagtt ggatgtcctg
     1621 accatatttc ttcttgaggg cagtagtaac taggcgataa gccagattgg cattacgaga
     1681 gaggataggc ccgtggaagt aggaaccaaa gacattctta taatgaaccc cttcaccgac
     1741 cttttcttcg ttgtttccat ttccatagac aacctgtccc agcggttttt ggtcatcaga
     1801 gaggaaggta cggccttggt gattttcaaa tccatagtag gtttcatcga aatcttcatt
     1861 gtgaatcttg atgtcaccga taaaacggtt attggtctgg ttgagcgtgt agtgtcccat
     1921 gacccctagc ccttcgatac gttttcctga agcttcaaca taatattgac ccaatagttg
     1981 gaaaccaccg cagatagcca gaactacacc gtcgttttgg atgtagttgt caatgctctc
     2041 ttttttagca ggtaggtcgt ctgcaatgat actttgttca aagtcttgac caccaccgaa
     2101 aaaggcgatg tcgtagtgat tttcatcaaa gtcatcatgg agagaaacga tgtcaacggt
     2161 cacatgggct cccagttttt cagccacata cttgagcatg aggatgtttc cattgtcccc
     2221 gtaggtattc atgagatttc cgtagaggtg ggcaatgttg agctgatagg ggtaattgcc
     2281 atcttttgag gaaagtgaag tataaaccat tagttcatct cctttctaac aatctgacga
     2341 ctagccagca gttcacgaaa ttccagcatg gcagtataag ttgccagaat ataggcatgc
     2401 ttgcagtctt gattctcaat ggtcttgaga acttgctcca gattactcgt ttcagtgatt
     2461 ttctcagctg gatagccagt cactcggagg cgacgagcga tttcagaatg acgaacaccg
     2521 ccagcgttga tttcaggaat gtccatgtca gtgatttgtt caaagtctgc atcccagatc
     2581 cagctagtgt caattccatc tgcatagttg gcattaagga ggacagatag gctaaatgga
     2641 taaggtgcta gtttgatcat ttcgatagct tgggttgcac cgactggatt tttaatcaag
     2701 acaagggtac attccttgtc accgatatga aaggtttctt ggcgtccaaa gacagcacgg
     2761 ctcttgtcaa atccctgttt gatgagttgc gaatcgacac ctaggaaacg ggcgatggcc
     2821 acagcagcta gggcgttata gatattatag agcccgccga tttggatacc gtattcttgg
     2881 ccgtctatga caaagcgaga gcgattgttg gtcaactcaa ccagttttgt caaacgatag
     2941 tcgagatcag gacgtttaca tccacaacct tcacagatat aggcacccaa gtttgcatag
     3001 gtattatgct catatttgag gatgccttgg cagtcaggac agagaatccc ttcggtattg
     3061 tagtgagcca gttgggctgg tcctttttcc aagtcaaaac caaaatactc tatagggttt
     3121 ggaatagttg gcttgtagaa aagtggactg tctccgttaa ggagaacagt agcagttgga
     3181 actttccgaa tggcatccaa tatcatgtta taggtagtat agatttcacc gaaacggtcc
     3241 atctggtcac ggaagatatt agtaatgaca aaaagactag gctggatata gtcacagata
     3301 cgagatagac tggcttcgtc gatttctagg acggcaatat ttttcccagt tttagaagat
     3361 ttggctgtta agaaggttgt cgcaattcct gtaatcatgt tggcaccgct tgggttggtc
     3421 agaacttgac cataaacttc ttttaaaata ccgacagtga gggcagttgt caaggttttt
     3481 ccgttggttc cagtgaccac gacaatctcg tagttcttag ctaggttttg taaaatatct
     3541 ttatcaaatt gaagggcgac tttacctggg agcgtacttc cacggccaag acggcttaaa
     3601 atgaagtggg aagaacgccc agcaagaagg cccaaagtag tttttaagtt catgtttcta
     3661 ttatatcata aaagaggaga aagacagatt tgagattccg cagaagtaaa aacagcccaa
     3721 agagggctgt tcgatacgat taaatctcaa cttaaatcgc aaacaagtca ttcaagttct
     3781 cagccaaggt tgggtgagtg aagatttgtt ttgtgaagta agtgtaagga atcttgttgt
     3841 ccatagcaac agtgatgatg ttgatgattt cttgagaacc ttctgagaag atgcttgctc
     3901 caagaatttc ttttgtttca gtattgacaa cagctttgaa ggcaccgcga aggtctccat
     3961 ttacgtgacc acgaggcatt gctgcaacgg ggatttcctt aacagcgtat ggaagtttca
     4021 aatcagctgc ttggctttca gtcaaaccaa cttgtgaaag tgcaggtgtg atgaacatag
     4081 tatttggcac attgagacgg tcttcaagtg tgtagctgcc atctccagca aggtagctgt
     4141 aaacaacacg gaagtcatca agtgaaatgt aagtaaattg aaggccaccg ttgacatctc
     4201 caactgcaaa gacaccagga acgtttgttt gacagtgttt gtctacttta atagcaccac
     4261 gttcagttag ttcaatatct gtattttcaa gttgaagtgg ttctacattt ggtttgcgtc
     4321 cagttgcgta gagaagggcg tcgaaacggt aagtttcgtc ttcagttacg acaagcactt
     4381 ggtcaccatc gtttttgatt tcagtagtat ggatattttg aagcaattca atgccatctt
     4441 cttccatgta ttgtttagca agagctgcga tggaaggttc tgcacgagga aggaaagtat
     4501 ccaaggcatc taggactgtg accttgcttc caagtttgtt gtaaaggccg gcaaattcaa
     4561 gaccgatatt tccgccacca aggattccaa gtttttcagg taatttgtcc aagttttgga
     4621 tacctgttga gtcaaagatg tttttgcttg tagcaagtcc agggattggc aagacgtttg
     4681 aaacagcacc agtgttgatg acgattgttt cagcagtcag ttctttcttt tcatcaccag
     4741 cttggatttc gatgacttta tttgaaagga agtgagcttc cgcatcaaag atatctacgc
     4801 ctgtaccagc aacagtcgca tagtttttac cgttgaggcg accagtgatc gtgtttttag
     4861 tagcaatcac ttcttcaaaa gacaagtcct tttcagcagc aactagcaag gttttagttg
     4921 ggatacaacc aatgttgata caagttccac cgtacatagc cttgctgcgt tcaacgaggg
     4981 caactttttt gccagctgaa gccaatttac ctgctagtgt tttaccagct ttaccaaatc
     5041 caataacaat taaatcgtat gttaacattt atcttcctcc tattcgaatt tcattctagc
     5101 acaagaaaaa aacttttgca caattctgct acggaaaaga cagaaaaaga taaaaacgct
     5161 ttccagacaa aaaactagta attttttgac aagcttgata aactaaaatc ctatctattt
     5221 ttatataaga tagaataaat gttcgaaaat aggaggtttt atgaaatcga atcgttatat
     5281 tattgccttt gctggggtca ttttacactt aatgctgggt tcgacttatg cctggagtgt
     5341 ttatcgtaac cctattattg aaaaaacggg atgggatcag gcttctgttg ccttcgcctt
     5401 tagtctagca atcttttgtt tgggcttatc ggctgcattt atggggcgtt tggtagaaaa
     5461 atttggtccg aaagtcatgg gaagtctatc tgcttttcta tacgcaggtg gaaatatctt
     5521 aacaggattt gcaatagacc gtcaggagct gtggttgttg tatctcgctt atggcatttt
     5581 aggtgggctt ggtttgggag caggctatat tacccctgtg tcgacgatta taaaatggtt
     5641 tcctgataaa cgtggtctcg caacaggttt agcgattatg gggtttggtt ttgcttcttt
     5701 attgactagt cccatagcgc aacacctcat cgcaggggta gggcttgtag aaacttttta
     5761 tattttagga gcaagttact ttattatcat gctcctagct tcacaattca ttaagcgtcc
     5821 aaatgagcaa gagcttgcaa ttttatcttc ttcagggaaa gaaaaaacag cctctttgac
     5881 gcaaggaatg gctgcaaatc aggctctaaa aagcaatcgg ttttatatac tttggattat
     5941 tttctttatc aacatagctt gtggtttagg cttaatttca gcggcatcgc caatggcaca
     6001 ggagatggct ggcttgtcta caagtcatgc agcagtaatg gtgggcgttt tagggatttt
     6061 caatggattt ggtcgcttgc tctgggcgag cttatctgac tatatcggtc gccctctaac
     6121 ctttagtata ttactgcttg ttaatctttt cttttctctc tcactttggc tctttacaga
     6181 ttccgtttta tttgtagtcg ctatgtctat tttgatgact tgctatggag ctggtttttc
     6241 attgatccca gcttatctca gtgatatttt tggaaccaag gaattggccg ctctgcatgg
     6301 atatatttta acagcttggg caatggctgg tttagcggga cctattttat tagcagagac
     6361 ttataaaatg gctcattcgt acacacaaac cttgttcgtt tttctcattt tatacagtat
     6421 cgccttggct ttgtcttatt atctaggtcg ttcaatcaaa aaagaaagtc aaaaaccgct
     6481 tacatgattt tctgtagaaa tggggctatc ttttgctctg gtcttgtgtt atactagata
     6541 ggttgcaaag aaaacagtac ttttcttttg tggaaaagaa gcaacacgat tttatatcta
     6601 gttatatgaa aatacgtcat aaaaagaaaa gtataaacta agccctatag ggtggcttcg
     6661 caccaccttt agaaagaaga ataacgtgaa atttaatgaa ttaaacttgt ctgctgattt
     6721 gctggcagaa attgaaaaag ctggttttgt agaagctagt cctatccaag aacaaactat
     6781 tcctttggcc cttgaaggca aggatgttat cggtcaagct cagactggta caggaaaaac
     6841 tgcagccttt ggcttgccta cccttgaaaa aatccgtaca gaagaagcga ctatccaagc
     6901 cttggtcatc gctccaactc gtgaactagc tgtccaaagt caagaagaac tcttccgctt
     6961 tggtcgtagt aagggagtca aagtccgttc agtatatggc ggatcaagca ttgaaaaaca
     7021 aattaaggct cttaaatctg gtgcccatat cgtggtggga actccaggtc gcctcttgga
     7081 cttgattaaa cgcaaggcct tgaaattaca aaacattgaa acccttatcc ttgacgaagc
     7141 ggatgaaatg cttaacatgg gcttccttga agacatcgaa gccattattt cccgtgtacc
     7201 tgagaaccgt caaactttgc ttttctcagc aactatgcca gatgccatca aacgtatcgg
     7261 tgttcagttt atgaaagccc ctgaacatgt caagattgca gctaaggaat tgacaacaga
     7321 attggttgac cagtactata tccgtgttaa ggaacaagaa aaatttgaca ccatgactcg
     7381 tctcatggat gtggcacaac cagaactcgc tattgtattt ggtcgtacca aacgccgtgt
     7441 ggatgaattg actcgtggtt tgaaaattcg tggcttccgt gcagaaggaa ttcatggcga
     7501 cctagaccaa aataaacgtc ttcgtgtcct tcgtgacttt aaaaatggca atcttgatgt
     7561 tttggttgcg acagacgttg cagcgcgtgg tttggatatt tcaggtgtga cccatgtcta
     7621 caactacgat attccacaag atcctgagag ttatgttcac cgtatcggtc gtacaggtcg
     7681 tgctggtaag tcaggtcaat ctattacttt tgttgctcca aacgaaatgg gttaccttca
     7741 aatcattgaa aacttgacta agaaacgcat gaaaggtctc aaacctgcaa gtgtagaaga
     7801 atccttccaa tcaaaaaaac aggtagctct caagaaaatc gaacgtgatt ttgcagatga
     7861 aaccattcgt gccaactttg agaaatttgg taaggatgct cgcaaattgg ctgctgagtt
     7921 tactccagaa gaattggcaa tgtatatctt gagtctgaca gtccaagacc cagatagcct
     7981 tccagaagtg gagattgcac gtgaaaaacc actaccgttt aaaccatcag gtaatggttt
     8041 cggtggtaaa gctaagggag gtcgtggagg ccgtcgtggg gacgaccgtc gagagcgtga
     8101 tcgccgtggc aatggtcgcc gtgatgagtt caaaaaagga agtcgtggca acgatcgttt
     8161 tgataaggaa aaacgttacc gtaaggataa taaaaaacca cgcaatactt taagcgaaaa
     8221 gcaaacaggc tttgttattc gtaacaaggg cgataaataa gaaaaagcgg ttcaaaatga
     8281 atcgcttttt tatataagga gaccgaatgt gaaaagataa ataaaattat tatattatct
     8341 tttataatgt tatgatacac aaaaataggc aacttgtcaa tagaaaagga acaatttaat
     8401 taaaaatatt ctggttttta attaaattgt aagtcaatgc aagtcaataa ggaattttca
     8461 gataattatt gaaaaagaga cgtttttatg ttataatgat agcgattaaa ttcgaggtga
     8521 aaaatggcac atttattaga aaaaactaga aaaattacat caattttgaa acgctcagag
     8581 gagcagttgc aggatgagct cccttacaac gctattacgc gtcagttagc ggatattatt
     8641 cattgcaatg cctgcattat caatagtaag ggacgtctgc ttggctattt tatgcgttat
     8701 aaaacaaata cagatcgcgt agagcaattc ttccaaacta agattttccc agatgactac
     8761 gttcaagggg ctaatatgat ttacgaaaca gaagcaaact tgcctgttga gcatgatatg
     8821 agtattttcc ctgttgagag tagagatgat tttccagatg gcttgacgac tattgcaccg
     8881 attcatgtat cggggattcg ccttggttct ttgattattt ggcgtaatga taaaaaattc
     8941 gaagatgagg acttggttct tgttgagatt gccagtaccg ttgttgggat tcagcttctt
     9001 aacttccaac gtgaagaaga tgagaaaaat attcgtcgtc gtactgctgt caccatggcg
     9061 gtcaataccc tttcttactc cgaactccgt gctgtttcag caattttagg ggaattaaat
     9121 ggaaatgaag ggaagttgac tgcgtcagtg attgcagatc gtatcggaat cactcgctct
     9181 gtgattgtca atgctcttcg taaacttgag tctgcgggga ttattgaaag tcgctcactt
     9241 ggaatgaagg gaacctatct taaggtcttg atttcagata tttttgaaga agtgaagaaa
     9301 agagattact aatgacaaag gctttaattt cgattgatta tacagaagat tttgttgctg
     9361 atagtgggaa gctgacagca ggtgctccag ctcaggcgat ttcggatgcc attagcaagg
     9421 taactcgatt agcttttgaa cgaggagatt atatcttctt tactattgat gctcatgaag
     9481 aaaacgattg tttccatccg gaaagtaagt tatttcctcc tcataatctg attgggacga
     9541 gtggacggaa tttatatgga gatttgggga tcttttatca agagcatggt tcagacagtc
     9601 gtgtcttttg gatggataaa cgccattact cagctttttc agggactgac ctagatattc
     9661 gtttgagaga gcgtagagtg tctaccgtta tcttaacagg tgtcttgacg gatatctgtg
     9721 tcctacatac agctatagat gcctataatc taggatatga catcgagatt gttaaaccag
     9781 ctgttgcttc catctggcct gaaaatcatc aatttgccct aggtcatttc aaaaatacac
     9841 tcggagctaa gttagtagat gaaaatctaa atgaactttc tgagtaacct ggttggtgaa
     9901 aatgaaaaaa tttgaaaaaa agtgttgaca agcatcccaa aagttgatat actagtaaag
     9961 taatcgacgc ggggatggcg gaattggcag acgcgcagga ctaaggatcc tgtgaccgct
    10021 ttaggtcgtg agggttcaag tccctctctc cgcataggaa aagagttagc taaagctagc
    10081 tcttttgtat ttctctaaaa aattagaatc cagtcaaatg tagtggagaa tcagcgaaaa
    10141 tatgggaaaa ctgatccttg tttctgcttt tgtcatagaa gaataataaa gattatcttc
    10201 ttcaaattct ccgatattct ctaaagtttt gtgcaagttg cacagaactt ttttattttt
    10261 ttggtcatct tgccatagaa atataaagcg ttttcatcta taatataatt atcaaaagac
    10321 aaaaggagtt cacctcatgg tagaattgaa tcttaaaaat atttacaaaa aatatccaaa
    10381 cagcgaacac tattcagttg aagatttcaa cttgaacatc aaagataaag aatttatcgt
    10441 tttcgtagga ccttcaggat gtggtaaatc aactacactc cgtatgattg ctggtcttga
    10501 agacattaca gaaggtactg catctatcga tggcgtggtt gtcaacgacg tagctccaaa
    10561 agaccgtgat atcgccatgg tattccaaaa ctacgctctt tacccacaca tgactgttta
    10621 tgacaacatg gctttcggtt tgaaattgcg taaatacagc aaagaagaca ttaacaaacg
    10681 tgttcaagaa gcagctgaaa tacttggatt gaaagaattc ttggaacgta aaccagctga
    10741 cctttcaggt ggtcaacgtc aacgtgttgc catggggcgt gcgattgtcc gtgatgcgaa
    10801 agtattcttg atggacgaac ctttgtcaaa cttggatgcc aaacttcgtg tatcaatgcg
    10861 tgctgaaatc gctaaaattc accgtcgtat cggagctaca actatctatg taactcacga
    10921 ccaaacagaa gcgatgacac ttgcagaccg tatcgttatt atgtcagcta ctaagaaccc
    10981 tgctggtaca ggtactatcg gacgtgtaga acaaatcggt actcctcaag aagtttacaa
    11041 aaatccagtt aacaaattcg ttgcaggatt catcggaagc ccagctatga acttcatcaa
    11101 cgtgaaattg gttggtagcg aaattgtttc tgacggtttc cgtttgaaag tgccagaagg
    11161 agcattgaaa gttcttcgtg aaaaaggcta cgaaggaaaa gaattgatct ttggtatccg
    11221 tccagaagac gtgaatgcag aacctgcttt ccttgaaaca ttcccagact gtgttgtaaa
    11281 agcgactatc tctgtatcag aactgcttgg ttcagaatct cacctttact gccaagttgg
    11341 taaagacgag tttgttgcaa aagttgatgc tcgtgactac ttgcaaacag gtgcaacagt
    11401 tgagcttgga tttgacttga acaaagcaca cttcttcgat gtagaaactg aaaaaacaat
    11461 ctactaaaat aaataaaatt caaagcacta caagaaaaga tatctcttta tcaattgtag
    11521 tggagagata tcagttaatc tagggagaga aacaaaatgc ttctctcctt tttgctaggg
    11581 aagtcatatt atgcatctat attgtgatgc tctttaatac tcttcgaaaa tctcttcaaa
    11641 ccacgtcaac gtcgccttgc cgtacgtatg attactgact tcgtcagttt tatctgcaac
    11701 ctcaaagctg tactttgagc agcttacggc tagtttccta gtttgctctt tgatttccat
    11761 tgagtattat ttgtgggtac catctacaag tgaagctata tgcgtaaact acgtgagcaa
    11821 ttgaattcga actagagagg taataataaa tttatgctat agttatggtg acttgtatgc
    11881 ttttgattct agtttatcaa ataatagatt agaattgtca gataatatca ttttgtgtta
    11941 taatgaagaa aaaacagagg tgttcaaatg tcagaagcag gtcataagtt tttagcaaaa
    12001 ttggggaaaa aacgcttacg tccaggtgga aagcgtgcca cagattggtt aattgcagaa
    12061 ggaggatttt caaaagaaaa gagaatacta gaggttgcgt gtaatagggg aactacagca
    12121 attgagttgg cacagcgttt tggttgcaag ataactgctg ttgatatgga tgctcaagct
    12181 ttagaagtgg ctaaaaaatc tgctggaacg gcaggtgttg ctcatttaat cagttttgaa
    12241 agagcaaatg caatgaaact tccttatcaa gatgctagtt ttgatattgt tataaatgaa
    12301 gctatgctga ctatgcaagc cgatcaagct aagaaaaaat gtgtaatgga atatctaagg
    12361 gtattaaaac ctggaggtct tctcttgaca catgatgtgc ttcttaagga agctaaagag
    12421 tctatcagac aggaattatc acaagcaatt catgtaaatg taggtccttt aactcaagat
    12481 ggttgggaac aggtgatgat agaatcaggt tattgtgatg tgaaagcatt gactggtgaa
    12541 atgacattaa tgaaattatc gggtatgatt tatgacgaag gtttgctagg aactttgaaa
    12601 atttgtgtaa atgcttgtaa aaaggagaat agaaagcagt ttttaactat gtataaaatg
    12661 tttgctaaga ataaacagaa attgggcttt attgcgatgg ctagttataa atcgtcaaaa
    12721 cgttagataa ttattgaagt taacttttcc ttttttcttt cttaaaaaat atgctataat
    12781 agagagtaaa aaactttgaa agaaagaaaa agatgaattt aaaagattac attgcaacaa
    12841 ttgaaaatta tccaaaggaa ggcattacct tccgtgatat tagtcctttg atggctgatg
    12901 gaaatgctta tagctacgct gttcgtgaaa tcgttcagta tgctactgac aagaaagtcg
    12961 acatgatcgt gggacctgaa gctcgtggat ttatcgtggg ttgtccagtt gcctttgagt
    13021 tgggaattgg ttttgcgcct gttcgtaagc caggtaaatt gccacgcgaa gttatttctg
    13081 ctgactatga aaaagagtac ggtgtcgata ctttgactat gcacgcggat gccattaagc
    13141 caggtcaacg tgttcttatt gtagatgacc ttttggcgac aggtggaact gttaaggcaa
    13201 ctatcgagat gattgaaaaa cttggtggtg ttatggcagg ttgtgccttc cttgttgaat
    13261 tggatgaatt gaacggccgt gaaaaaattg gtgactacga ctacaaagtt cttatgcatt
    13321 attaatgaaa acagtcccta gggctgtttt ctctacacta ggatataaaa atagactata
    13381 actagttaga gaaaaactat aattgaaaac tatatcttct tgcagtataa taaaaggact
    13441 aagtgtttga gatttgtctt caaacatatg caattattcc tgaaagagta cagttaggag
    13501 agggttatgc cgattcgaat tgataaaaaa ttgccagctg ttgagatttt acggacagag
    13561 aatatctttg tcatggatga tcaacgtgct gcccaccaag atatccgtcc tttgaagatt
    13621 ttaattttaa atctcatgcc acagaaaatg gtcacagaga cccagttgtt gcgccacttg
    13681 gctaatacac ccctacaact ggatattgat tttctctata tggagagcca ccgttctaaa
    13741 acaactcgtt cagagcacat ggagaccttc tataaaactt ttcctgaagt caaggatgag
    13801 tattttgatg ggatgatcat cacgggtgct ccagttgagc atttaccatt tgaggaagtg
    13861 gactattggg aggaatttag acagatgctt gagtggtcta agactcatgt ctattcgacc
    13921 cttcatatct gttggggggc tcaggctggg ctttatctgc gctatggtgt agaaaaatac
    13981 cagatggaca gtaagctatc aggtatttat cctcaggaca ccctaaaaga gggtcacctt
    14041 ctatttagag gctttgatga tagctatgta tcccctcatt cacggcacac ggagatttct
    14101 aaggaagagg tcttaaacaa gaccaatctc gagattttat cagaaggacc tcaggttggg
    14161 gtttctattt tggccagtcg tgatttacga gaaatttata gttttggtca tttggagtat
    14221 gaccgtgata ccttggcaaa agagtatttt cgagatcgtg atgcaggttt cgacccacat
    14281 attccagaaa attactttaa agatgatgat gttaatcagg taccttgtct ttgttggtct
    14341 tcatctgcag ccctcttttt cagtaattgg gtaaaccatg cggtctatca ggagacgcct
    14401 tttgactgga gaaagataga agatgatgca tctgcatata ggtatttata agaggaatta
    14461 tgacatattt agacgctttt aaatcaggta ccttggtttt accgagtgcc ctgctcttgc
    14521 attttaagga actctttcct tctagcgacg attttctggt ttggcaattt ttctatttgc
    14581 aaaatacgac aggcttagaa gaaatatcgc caagccagat tgctgaaagg attggcaagg
    14641 aaatttcgga tgtcaaccag tccatttcta atctgacgga aaggggactg ctccagtatc
    14701 gtactatcga attaaatggc gaaattgaat tgctctttga tgctagtttg gccttggaac
    14761 gtttggatga cctgtttgga gcagttcatt caagttcaga ccagctaaca ccacaaaacc
    14821 agctcaagga tttggtggaa accttccagc aggagttggg acgattgttg acgccttttg
    14881 agattgagga tttgaccaag acactaaagg aagatggaac cagtgctgac ttgattaagg
    14941 aggctcttcg tgaagctgtt ttgaacggaa aaccaaactg gaagtacatt caggcgattt
    15001 tgagaaactg gcgccatgaa ggaatcaaga gtgtggctca aattgaggcc aagagagcag
    15061 aaagagaagc aagcaatcct cagttgacac aggtatctgc agatttcata aatgccatgg
    15121 atctctggaa ggattaatcc atgcaagtag gcttgaaatc cgagtaagat ttgcaagctg
    15181 tgtataattg tgatagaata aatagaaaat aaattgaaaa aagaggtatg tgaaatgtca
    15241 cgtaaaccat ttatcgctgg taactggaaa atgaacaaaa atccagaaga agctaaagca
    15301 ttcgttgaag cagttgcatc aaaacttcct tcatcagatc ttgttgaagc aggtatcgct
    15361 gctccagctc ttgatttgac aactgttctt gctgttgcaa aaggctcaaa ccttaaagtt
    15421 gctgctcaaa actgctactt tgaaaatgca ggtgctttca ctggtgaaac tagcccacaa
    15481 gttttgaaag aaatcggtac tgactacgtt gttatcggtc actcagaacg ccgtgactac
    15541 ttccatgaaa ctgatgaaga tatcaacaaa aaagcaaaag caatctttgc gaacggtatg
    15601 cttccaatca tctgttgtgg tgaatcactt gaaacttacg aagctggtaa agctgctgaa
    15661 ttcgtaggtg ctcaagtatc tgctgcattg gctggattga ctgctgaaca agttgctgcc
    15721 tcagttatcg cttatgagcc aatctgggct atcggtactg gtaaatcagc ttcacaagac
    15781 gatgcacaaa aaatgtgtaa agttgttcgt gacgttgtag ctgctgactt tggtcaagaa
    15841 gtcgcagaca aagttcgtgt tcaatacggt ggttctgtta aacctgaaaa tgttgcttca
    15901 tacatggctt gcccagacgt tgacggtgcc cttgtaggtg gtgcgtcact tgaagctgaa
    15961 agcttcttgg ctttgcttga ctttgtaaaa taatcagtaa gtagcaaaag ctaggtggaa
    16021 cagcattcag atgtctgtta cattttttat aggagagcaa agattgaaaa caaaaattgg
    16081 attagcaagt atctgtttac taggcttggc aactagtcat gtcgctgcaa atgaaactga
    16141 agtagcaaaa acttcgcagg atacaacgac agcttcaagt agttcagagc aaaatcagtc
    16201 ttctaataaa acgcaaacga gcgcagaagt acagactaat gctgctgccc actgggatgg
    16261 ggattattat gtaaaggatg atggttctaa agctcaaagt gaatggattt ttgacaacta
    16321 ctataaggct tggttttata ttaattcaga tggtcgttac tcgcagaatg aatggcatgg
    16381 aaattactac ctgaaatcag gtggatatat ggcccaaaac gagtggatct atgacagtaa
    16441 ttacaagagt tggttttatc tcaagtcaga tggggcttat gctcatcaag aatggcaatt
    16501 gattggaaat aagtggtact acttcaagaa gtggggttac atggctaaaa gccaatggca
    16561 aggaagttat ttcttgaatg gtcaaggagc tatgatgcaa aatgaatggc tctatgatcc
    16621 agcctattct gcttattttt atctaaaatc cgatggaact tatgctaacc aagagtggca
    16681 aaaagtgggc ggcaaatggt actatttcaa gaagtggggc tatatggctc ggaatgagtg
    16741 gcaaggcaac tactatttga ctggaagtgg tgctatggcg actgacgaag tgattatgga
    16801 tggtgctcgc tatatctttg cggcctctgg tgagctcaaa gaaaagaaag atttgaatgt
    16861 cggctgggtt cacagagatg gtaaacgcta tttctttaat aatagagaag aacaagtggg
    16921 aaccgaacat gctaagaaaa tcattgatat tagtgagcac aatggtcgta tcaatgattg
    16981 gaaaaaggtt attgatgaga acgaggtgga tggtgtcatt gttcgtctag gttatagcgg
    17041 taaagaagac aaggaattgg cgcataacat taaggagtta aaccgtctgg gaattcctta
    17101 tggtgtctat ctctatacct atgctgaaaa tgagaccgat gctgagaatg acgctaaaca
    17161 gaccattgaa cttataaaga aatacaatat gaacctgtct taccctatct attatgatgt
    17221 tgagaactgg gaatatgtaa ataagagcaa gagagctcca agtgatacag acacttgggt
    17281 taaaatcatc aacaagtaca tggacacgat gaagcaggcg ggttatcaaa atgtgtatgt
    17341 ctatagctat cgtagtttat tacagacgcg tttaaaacac ccagatattt taaaacatgt
    17401 aaactgggta gcggcctata cgaatgcttt agaatgggaa aacccttatt attcaggaga
    17461 aaaaggttgg caatatacct cttctgaata catgaaagga atccaagggc gcgtagatgt
    17521 cagcgtttgg tattaagcga tgatttgaaa gagggatgtg atagtagcac cctctttttc
    17581 tttgttttat gatagttcat cctcgagtaa attcaagatc ttgctcggaa atgaagctta
    17641 tatagtagat tgaatataga caaatacctt gtgattggta aaacatttta gaaattcatt
    17701 tacctttcct aatcgacttg gtttcatctt atttcaatct attatagtat tggggaattt
    17761 cttcaaacca catcagcttg gtcagttcta cctgcgacct caaaacttgt gctttggtca
    17821 agctgggttt agtttcctag tttgctgatg gatttccatt gactataagc atccaaccct
    17881 ctttttgtct tctaaagaat tcttaaatta tcagtctatt gcaacttttc tcatataagt
    17941 tctttgtctt gctattggtt ttccttagta gtatactaag gtagtaatca ttaagaagtg
    18001 gttacaaaaa ataatgaatg aggtaaagaa aatggtagaa ttgaaaaaag aagcagtaaa
    18061 agacgtaaca tcattgacaa aagcagcgcc agtagcattg gcaaaaacaa aggaagtctt
    18121 gaaccaagct gttgctgatt tgtatgtagc tcacgttgct ttgcaccaag tgcactggta
    18181 tatgcatggt cgtggtttcc ttgtatggca tccaaaaatg gatgagtaca tggaagctct
    18241 tgacggtcaa ttggatgaaa tcagcgaacg cttgattaca ctcggtggaa gcccattctc
    18301 tacattgaca gagttccttc aaaatagtga aatcgaagaa gaagctggtg aataccgtaa
    18361 tgttgaagaa agcttggaac gtgttcttgt tatctaccgt tacttgtcag aacttttcca
    18421 aaaaggtttg gatgtcactg atgaagaagg tgacgatgtg acaaacggta tctttgcagg
    18481 cgctaaaact gaaacagata aaacaatttg gatgcttgca gccgaacttg gacaagcacc
    18541 tggtttgtaa gaaataagga aacatagata aatctgtagg aaatttctta cagatttttt
    18601 ctattttgta agctattcca aaccagtctt tttttgagtt ttttgataaa atagtactat
    18661 cagtgaaaag gatggaagca tgactaagaa aatcgtagct atttgggccc aggatgaaga
    18721 gggtgtgatt ggtaagaaaa atcgtctgcc ttggcatttg ccagcagaat tgcagcactt
    18781 taaagaaaca actctgaatc atgctatctt gatggggcgt gtgacctttg atgggatggg
    18841 gcgtcgcttg cttccaaaac gggaaacctt gattttgacg cgtaatccgg aagaaaagat
    18901 agatggggtt gctacttttc aggacgtcca gtctgttctt gactggtatc aggctcaaga
    18961 aaagaatctc tacattatcg gtgggaagca aatttttcag gcttttgaag cttaccttga
    19021 tgaagtgatt gtcactcaca ttcatgctcg ggtggaagga gatacctatt tccctgaaga
    19081 gcttgacttg tctctttttg agacagtttc aagcaaattt tacgccaaag atgagaagaa
    19141 tccttatgat tttaccatcc aataccgcaa gagaaaggaa gtataatgga acggagttta
    19201 tttggtctat tcacggcttt tctgtgtttc atctgctttc tggcaggagc acaggctttt
    19261 cgtaaaaagc gttacgggct ttctatcctc ctttggttaa atgcctttac caatctggtc
    19321 aatagtattc atgcttttta catgacctta ttttagatag aatgacagta tagaatggaa
    19381 ggaaatcatg tctacaaata gaaaaaatga tatgatggtt tattgctcat tttgtggcaa
    19441 aaaccaagaa gaagtacaaa aaataattgc tggcaacaat gcttttattt gtaatgaatg
    19501 cgtggagtta gctcaggaaa tcattcgaga agaattggtt gaggaagtct tggcagactt
    19561 gtctgaggtg ccaaaaccaa ttgaactcct ccatatcttg aaccactatg taattggtca
    19621 agatcgtgcc aagcgtgcct tggcagtggc ggtttataac cactacaaac gcatcaattt
    19681 ccacgataca cgcgaagagt cagaagatgt ggatttgcag aagtcaaaca ttttgatgat
    19741 tggcccaact ggttcaggga aaactttcct tgcccagacc ttggctaaga gcttgaatgt
    19801 gccttttgct attgcggatg cgacagctct gacggaggct ggttatgtgg gtgaggacgt
    19861 ggaaaatatc ctcctcaaac tcttgcaggt tgctgacttt aacatcgaac gtgcagagcg
    19921 tggcattatc tatgtggatg aaattgacaa gattgccaag aagagtgaga atgtgtctat
    19981 cacacgtgat gtttctggtg aaggggtgca acaagccctt ctcaagatta tcgagggaac
    20041 tgttgctagc gtgccgcctc aaggtggacg caaacatcca caacaagaga tgattcaagt
    20101 ggatacaaaa aatatcctct tcatcgtggg tggtgctttt gatggtattg aagaaattgt
    20161 caaacaacgt ctgggtgaaa aagtcatcgg atttggtcaa aacaataagg cgattgatga
    20221 aaacagctca tatatgcaag aaatcatcgc tgaagacatt caaaaatttg gtattatccc
    20281 tgagttgatt ggacgcttgc ctgtttttgc ggctcttgag caattgaccg ttgatgactt
    20341 ggttcgcatc ttgaaagagc caagaaatgc cttggtgaaa caataccaaa ctttgctttc
    20401 ttatgatgat gttgagttgg aatttgacga cgaagccctt caagagattg ctaataaagc
    20461 aatcgaacgg aagacagggg cgcgtggact tcgctccatt atcgaagaaa ccatgctaga
    20521 tgttatgttt gaggtgccga gtcaggaaaa tgtgaaattg gttcgcatca ctaaagaaac
    20581 tgtcgatgga acggataaac cgatcctaga aacagcctag aggtgactat ggaacttaat
    20641 acacacaatg ctgaaatctt gctcagtgca gctaataagt cccactatcc gcaggatgaa
    20701 ctgccagaga ttgccctagc agggcgttca aatgttggta aatccagctt tatcaacact
    20761 atgttgaacc gtaagaatct cgcccgtaca tcaggaaaac ctggtaaaac ccagctcctg
    20821 aactttttta acattgatga caagatgcgc tttgtggatg tgcctggtta tggctatgct
    20881 cgtgtttcta aaaaggaacg tgaaaagtgg gggtgcatga ttgaggagta cttaacgact
    20941 cgggaaaatc tccgtgcggt tgtcagtcta gttgaccttc gtcatgaccc gtcagcagat
    21001 gatgtgcaga tgtacgaatt tctcaagtat tatgagattc cagtcatcat tgtggcgacc
    21061 aaggcggaca agattcctcg tggtaaatgg aacaagcatg aatcagcaat caaaaagaaa
    21121 ttaaactttg acccaagtga cgatttcatc ctcttttcat ctgtcagcaa ggcagggatg
    21181 gatgaggctt gggatgcaat cttagaaaaa ttgtgaggaa aagaaaatgg caaaaacaat
    21241 tcatacagat aaggccccaa aggctatcgg accctatgtt caaggaaaaa tcgttggcaa
    21301 ccttttgttt gctagcggtc aagttcccct atcccctgaa actggggaaa ttgtaggaga
    21361 gaatatccaa gaacagacag agcaagtctt gaaaaacatc ggtgctattt tggcagaagc
    21421 aggaacagac tttgaccatg ttgtcaaaac aacttgtttc ttgagcgata tgaacgactt
    21481 tgttcctttt aatgaggttt accaaacggc cttcaaagag gaattcccag ctcgttcagc
    21541 tgtggaggta gctcgtcttc ctcgtgatgt aaaagtcgaa attgaagtca tcgcagagat
    21601 tggataagct agttgaagtt tggtgttgcc aaacttcttt tgatataagg agaaaaagat
    21661 gacaaagaaa caacttcact tggtgattgt gacagggatg agtggcgcag ggaaaactgt
    21721 agccattcag tccttcgagg atctaggtta tttcaccatt gataatatgc cgccagctct
    21781 cttgcctaag tttttgcagc tggttgaaat taaggaagac aatcctaagt tggccttggt
    21841 agtggatatg cgtagccgtt ctttcttttc agagattcaa gctgttttgg atgagttgga
    21901 aaatcaagat ggtttggatt tcaaaatcct ctttttggat gcggctgata aggaattggt
    21961 cgctcgttac aaggaaacca gacggagtca cccactagca gcagacggtc gtattttaga
    22021 tggaatcaag ttggaacgtg aactcttggc acctttgaaa aatatgagcc aaaatgtggt
    22081 ggatacgact gaactcactc cacgtgagct gcgcaaaacc cttgcagagc agttttcaga
    22141 ccaagaacaa gctcagtctt tccgtatcga agtcatgtct ttcggattta agtatggaat
    22201 cccgattgat gcggacttgg tctttgatgt ccgtttcttg ccaaatccct attatttacc
    22261 agaactgaga aaccaaacgg gtgtggatga acctgtttat gattatgtca tgaaccatcc
    22321 tgagtcagaa gacttttatc aacatttatt ggccttgatt gagccgattc tgccaagtta
    22381 ccaaaaggaa ggtaagtccg ttttgaccat tgccatggga tgtacgggtg gacaacaccg
    22441 tagtgtggca tttgctaaat gcttggcgca ggacttatcc aagaattggt ctgttaatga
    22501 agggcatcgc gacaaagacc gcagaaagga aacggtaaac cgttcatgag aaaaccaaag
    22561 ataacggtga ttggtggagg gactggaatt cccgtcattc taaaaagtct gcgggaaaaa
    22621 gatgtggaaa tcgcagctat cgtgacggtg gcagatgatg gtggttcttc aggtgaactc
    22681 cgaaaaaata tgcaacagtt gacaccgcca ggtgatcttc gtaatgtcct tgtggccatg
    22741 tcggatatgc ctaagtttta tgagaaggtc tttcagtatc ggttctctga ggatgccgga
    22801 gcctttgctg gccatccatt gggaaatctc atcattgctg gcttgtcaga aatgcagggt
    22861 tcaacctata atgccatgca gttattgagc aaatttttcc atacaacagg gaaaatttat
    22921 ccttccagtg accatccttt gacccttcat gcagtctttc aggatgggac agaagtggtt
    22981 ggagagagtc atattgtaga ccatcgaggc atagttgaca atgtctatgt gactaatgct
    23041 ctaaacgatg atacgcctct ggccagccgt cgagtagtgc agaccatcct tgaaagtgac
    23101 atgattgtcc tagggccagg ttccctcttt acctctattt tgcccaatat cgtgattaag
    23161 gaaattgggc gggctctttt ggaaaccaag gcagaaattg cctatgtctg caatatcatg
    23221 acccaacgtg gggagacgga acactttaca gatagcgacc acgtggaagt cttgcatcgt
    23281 caccttggtc gcccttttat cgacactgtc ttggtgaata ttgaaaaagt gcctcaggaa
    23341 tacatgaatt ccaaccgttt tgatgaatac ttagtgcaag tggaacacga ttttgtaggt
    23401 ctttgtaagc aagtttcgcg cgtgatttca tctaacttcc ttcgtctgga aaatggcggt
    23461 gccttccacg atggagattt gattgtggac gagttgatgc gcattataca ggtgaaaaaa
    23521 tgagtttcac agtagcagta aaagaagaaa tcctgggcca acaccatctg agctggcatg
    23581 aattatctgc cattatcaaa atgtctggta gcatcggtct ctcgacttcg ggcttgactt
    23641 tgtcagttgt gacagaaaat gccaaactgg cccgtcacct ctatgagtcc tttcttcatt
    23701 tctatgaaat caaatctgaa attcgtcacc accaacgtag caatcttcgc aagaatcgcg
    23761 tctataccgt ttttacagat gaaaaggtgc aggatttgtt aagtgatttg cacttggcag
    23821 actctttctt tggcctggaa acaggtattg atgaggcgat tttatcggat gaggaagcag
    23881 gtcgtgccta tctctgtggc gctttcttgg caaatgggag cattcgtgac cctgagtcag
    23941 gcaagtacca gttggaaatc agttctgttt atctggacca cgcgcaagga attgcctccc
    24001 ttctccaaca gtttttactg gatgccaagg tgcttgagcg caagaagggg gctgtgacct
    24061 atctccagcg agcagaagac attatggact tcttgatagt aatcggagcc atgcaggcac
    24121 gtgatgattt tgagcgggtt aagattttgc gagaaacccg taacgacctc aatcgggcta
    24181 ataatgccga gacagctaat atcgctcgga cagtttctgc cagcatgaag accattaaca
    24241 atatcagtaa aatcaaagat atcatgggct tagaaaattt gccagtagat ttgcaggaag
    24301 tggcgcaact gaggattcag cacccagact actctatcca gcagttagca gatagtctca
    24361 gcacccctct gaccaaaagt ggtgtcaatc acagactcag aaaaatcaat aagat
//
LOCUS       DAVHBD010000033        24275 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000033 DAVHBD010000000
VERSION     DAVHBD010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.033"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(49..243)
                     /locus_tag="VVK04_001427"
                     /pseudo
     CDS             complement(49..243)
                     /locus_tag="VVK04_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(305..754)
                     /locus_tag="VVK04_001428"
     CDS             complement(305..754)
                     /locus_tag="VVK04_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU3990072.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIASIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKIHRVS"
     gene            complement(756..1514)
                     /locus_tag="VVK04_001429"
     CDS             complement(756..1514)
                     /locus_tag="VVK04_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU3990073.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1629..3608)
                     /gene="pknB"
                     /locus_tag="VVK04_001430"
     CDS             complement(1629..3608)
                     /gene="pknB"
                     /locus_tag="VVK04_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU3990074.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENSSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLTFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3605..4345)
                     /locus_tag="VVK04_001431"
     CDS             complement(3605..4345)
                     /locus_tag="VVK04_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU3990075.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4360..5673)
                     /gene="rsmB"
                     /locus_tag="VVK04_001432"
     CDS             complement(4360..5673)
                     /gene="rsmB"
                     /locus_tag="VVK04_001432"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU3990076.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLNLQGDERVLDACAAPGGKTAHIASYFTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5666..6601)
                     /locus_tag="VVK04_001433"
     CDS             complement(5666..6601)
                     /locus_tag="VVK04_001433"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU3990077.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVTHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6614..9010)
                     /locus_tag="VVK04_001434"
     CDS             complement(6614..9010)
                     /locus_tag="VVK04_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU3990078.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9076..9390)
                     /locus_tag="VVK04_001435"
     CDS             complement(9076..9390)
                     /locus_tag="VVK04_001435"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU3990079.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9415..10041)
                     /gene="gmk"
                     /locus_tag="VVK04_001436"
     CDS             complement(9415..10041)
                     /gene="gmk"
                     /locus_tag="VVK04_001436"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU3990080.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10171..11784)
                     /locus_tag="VVK04_001437"
     CDS             complement(10171..11784)
                     /locus_tag="VVK04_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU3990081.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMANELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11976..13073)
                     /locus_tag="VVK04_001438"
     CDS             complement(11976..13073)
                     /locus_tag="VVK04_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU3990082.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKTVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWQEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            complement(13083..13829)
                     /locus_tag="VVK04_001439"
     CDS             complement(13083..13829)
                     /locus_tag="VVK04_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU3990083.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(13932..14285)
                     /gene="rsfS"
                     /locus_tag="VVK04_001440"
     CDS             complement(13932..14285)
                     /gene="rsfS"
                     /locus_tag="VVK04_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU3990084.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(14298..14798)
                     /locus_tag="VVK04_001441"
     CDS             complement(14298..14798)
                     /locus_tag="VVK04_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU3990085.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(14799..15392)
                     /gene="yqeK"
                     /locus_tag="VVK04_001442"
     CDS             complement(14799..15392)
                     /gene="yqeK"
                     /locus_tag="VVK04_001442"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU3990086.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRSFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(15392..16021)
                     /locus_tag="VVK04_001443"
     CDS             complement(15392..16021)
                     /locus_tag="VVK04_001443"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU3990087.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16073..16384)
                     /gene="yhbY"
                     /locus_tag="VVK04_001444"
     CDS             complement(16073..16384)
                     /gene="yhbY"
                     /locus_tag="VVK04_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU3990088.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(16598..17704)
                     /gene="yqeH"
                     /locus_tag="VVK04_001445"
     CDS             complement(16598..17704)
                     /gene="yqeH"
                     /locus_tag="VVK04_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU3990089.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(17707..18297)
                     /locus_tag="VVK04_001446"
     CDS             complement(17707..18297)
                     /locus_tag="VVK04_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU3990090.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QVQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(18249..19157)
                     /locus_tag="VVK04_001447"
     CDS             complement(18249..19157)
                     /locus_tag="VVK04_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU3990091.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(19214..19774)
                     /locus_tag="VVK04_001448"
     CDS             complement(19214..19774)
                     /locus_tag="VVK04_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU3990092.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20163..20624
                     /locus_tag="VVK04_001449"
     CDS             20163..20624
                     /locus_tag="VVK04_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HEU3990093.1"
                     /translation="MIGTFAAALVAVLASFIVPIEITLNSANTEIAPPDGIGQVLSNL
                     LLKLVDSPVNALFTANYIGILSWAVIFGIAMREASKNSKELLKTIADVTSKIVEWIIN
                     LAPFGILGLVFKTISDKGVGSLANYGILLVPLVTTMLFVAPVVNPLIASSL"
     gene            20621..21121
                     /locus_tag="VVK04_001450"
     CDS             20621..21121
                     /locus_tag="VVK04_001450"
                     /inference="COORDINATES: protein motif:HMM:NF010151.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HEU3990094.1"
                     /translation="MRRNPYSLVWNCLRVSGVTAFFTRSSATNIPVNMKLCHDLGLNP
                     DTYSVSIPLGSTINMAGVAITINLLTLAAVNTLGIPVDFATAFVLSVVAAISSCDASG
                     IAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIGVIQDSCETALNSSTDVLFTAVAEY
                     AATRKK"
     gene            21189..22142
                     /locus_tag="VVK04_001451"
     CDS             21189..22142
                     /locus_tag="VVK04_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU3990095.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            22286..22666
                     /locus_tag="VVK04_001452"
     CDS             22286..22666
                     /locus_tag="VVK04_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU3990096.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            22765..22986
                     /locus_tag="VVK04_001453"
     CDS             22765..22986
                     /locus_tag="VVK04_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU3990097.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            23003..23317
                     /gene="trxA"
                     /locus_tag="VVK04_001454"
     CDS             23003..23317
                     /gene="trxA"
                     /locus_tag="VVK04_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU3990098.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            23622..24155
                     /gene="queF"
                     /locus_tag="VVK04_001455"
     CDS             23622..24155
                     /gene="queF"
                     /locus_tag="VVK04_001455"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU3990099.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         6608 a         5663 c         4802 g         7202 t
ORIGIN      
        1 ttccatagaa tgacatttct attttaccag aataattggc tagttgattt ttttaggacg
       61 atttattttt acctctgttg catccacaat caccgtattc tcagcactaa gatgagtttt
      121 tgaaatcgta acaccacttt gaacaagagt tacttcaacc cattggctcc gacggattaa
      181 gttgctttcg tggataccaa aatcagccgt aatttcttca taagtgcggt attctcgcac
      241 atatagaaag cgttgttaat ttatttatct catttttcag aaaattcttt tatttctgta
      301 aagtctacga tactcgatgt atttttatat aatgatacag tctgagaatc actgttccgc
      361 tagccattcc aatagagatt accagagcca acatgacaac caaggtcgca cttgccagtg
      421 ctttattata gtcccctgtc acaaaaaagg cagttgttcg gtaggagaga taacctggaa
      481 ccagcggtgc caaaatggcc aagataaaga ccacagcagg tgtcttataa agaatactta
      541 aaatctggct gacacaagaa ccaataatgg atgcaatgaa ggtagctaca atgacattgg
      601 tcggttcctt gagcaagaga tagattagcc agacagtcat gcccaaaatc cctccaggta
      661 agagcataga ccgttgcaca ttgagtacga ttaaaaaagt gataatggca agaaaacttg
      721 ctactgcttg taataaaaag gttgttagtg tcatattagt tcatcaatac caaggcgaca
      781 gaagttcctg cccctaaagc gagggtaatg agcagggatt caaacatctt actcatacca
      841 gagtttatgt ggttggtcat aatatcacgg accgcattgg tcaaggcaat gcctggtaca
      901 aacggcatga ccgcaccagc tataatcaaa tctgccgttg aaggaaaacc tgtgtagcga
      961 gcccaaaact gggcaattat cccaaagaca aaggctccag caaaggctgt cacaaaggga
     1021 attcggataa atttttccac atagagggaa aaggcaaaac caaataaggt cgccactcct
     1081 gccccaagtg cgtcgtagat atttccgcta aacataactg aaaagaaagg agcactaaag
     1141 gtcgcagcca gagttacctg caacttagta tagggaaggg gttgagcttg caaggccgtc
     1201 aattgcttaa aggctgtttc taagtcaatc tgccccccaa ctagctgacg agaaatctgg
     1261 ttcacatcgc agactttttc gatgttataa gaagaggagg tcacgcgctt catgcgcgaa
     1321 atattggtat tttcaataga gaaaaagata gcggcaggca tggcaaggac attgcaatcc
     1381 acaatcccct gcgaatgcgc gattcgaatc atggtatctt ctacacgatg gatttctgag
     1441 ccacttttaa ggagaatagt ccccgctagc ataatcacat caatgacggc atttaattct
     1501 tttgattctt ccatgctttc ctccttttat caactccctc tattctatca caaatctgga
     1561 ctcaaaaaaa atctttgcca tgaaatcatg acaaagattg attactcatt ttgattatcc
     1621 atctgctttt aaggagtagc tgaagttgtt ttaggtttgt agattgaaat cttgactcta
     1681 gtcttattta ggtctacctt ttcacctgct ctaggacttt gttcaacaac catgccttct
     1741 acactacctg caggcgctgt cgtcacttct acaacttcta tattagcttc cttaatccca
     1801 acaatttgaa tcaaattgtt cttagtaaac tccaagctgg aaccaatgta actcggcatg
     1861 gcaacacttg taactttttt agctactgtc aagacaattt gagtaggttt actcacatca
     1921 taagtcgttc cggcacctgg actttgtttc ataatcgttc ctggttcgct ttcgctggac
     1981 tcttcttcct ctatcttaat caaattctca ggaaccttct tctgcttgag ttctgagatt
     2041 acttctgtag agttccgtcc aatatagttc cctaattgaa tcgtcgtagc ttttttagct
     2101 actgtcaaaa caatttgagt tgccttgctc aagtcatagg tcgtaccttc tggtagactt
     2161 tgcttcagga ccgttccagc ctcactttca ttcgactctt cttcctcaat tttaatcaaa
     2221 ttatctggaa cttttttctc ttttaattcc gcgataacat cagaagattt ccggccgaca
     2281 taattactaa tttggaagga ttgtttgcct gatgagacaa ccagattaat tttcgttcct
     2341 tcttttcgac cagttccagc gccaggatct gtacggataa tccgcccttc ttccaccttt
     2401 tcactagcct ctgtcttctc ctcaccaatc tcaaaattgg cttttttgag cgttgccttg
     2461 gcctctgcaa ctgtctgacc tgccacatct ggaatggcaa tggttgcagg agttctggat
     2521 agtatccaaa taagagaagc tgccaccaat acaaggctgg ccaacaaaat caggtaacgc
     2581 atcttaaatc tatgtttttt cggtgcttgt ggttggtaag tttcctctgt cacagcctgg
     2641 cttgggtttt tgattgattt gtgttctgtc tgcgcttgaa ccttaggaat agatgtcaag
     2701 gtactctgag aaaccttcgg caaggtcttg gtatctgcct tgctcgtttc atcaaaggtt
     2761 aacttacttt catttctacg attgtaggac aagctactag acaagtctac atacatctct
     2821 gaaaccgagc gatagcgatt ggtcaacttt ttagcagttg ccttgataat aacattttct
     2881 aaagcctgag gtacagatga attttctgca ataacggacg gcaggggttt ctggaaatgc
     2941 tggagggcaa tggtcaccgc gctatccccg tcataaggga tatggcctgt caacatctca
     3001 tagaaaataa tccccatggc atagatatca ctctgcacag tcgccttcga accacgcgcc
     3061 tgctctggtg acaagtaatg aactgagccc aacatcgagt tagtctgggt cagacttgtc
     3121 tctgcaaagg ctacagcaat cccaaagtct gtgaccttgg cagtcccatc tggtgtcaaa
     3181 aggatatttt gaggtttcaa gtccctgtga acaattcctc gagtatgggc caagcgcata
     3241 gccaagagaa tttgtcccat gatacggact gcttcttcat tagaaagagg ataatgttcc
     3301 ttgatatagc gtttgaggtc tagtccagca acatactcca ttgcaagata ctgttgaccg
     3361 tcttcctcac caatatctgt tatccgaacg atatgaggat ggtctagatc tgccatagct
     3421 ctcgcttcac gctgaaaacg agctacagct atcgggtccg tctggtagtt ggtcctcaga
     3481 accttcactg ccacttcttc cccatctaag attaagtctt tggctaggta gacatccgcc
     3541 atgcctcctc gaccaatctg tttgacaatc cgatagcgtc cggcaaaaat cttgccgatt
     3601 tggatcattc tgcatcctcc tcgttcatag aaacaagagc aaccgtaatg ttgtctaaac
     3661 ctcctgcatt gttagcaaaa cgaacaagtg tctccgtttt atctgctaaa ggaatatcac
     3721 tggttacaat atcacgaatc tcactgcctg aaatcatgtt ggtcaagccg tcactattga
     3781 gcaaaagata gtcacctgac tcaaggataa ctgtcccaaa atcaggctga atttcatctt
     3841 tttgcccaat agactgggtg ataatatttt tttgcggatg agcttctgcc tcttctggtg
     3901 tcaattgacc agccttgagc aattcattaa ccaaggaatg atcgctcgtc aactgatggt
     3961 attcttctcc acgaatcaag ccgatacgcg aatcaccaat atgagcatag atagcctgat
     4021 tatcaataat agcaaggact tccaaagtag ttcccatgcc tctgtaagct tcatcctgac
     4081 caagctggtg aatcttttga ttttcaattt ctaggtaatg ggcgaaccat tcacgcactt
     4141 cattgactgt atcaatctgg gtatcaaccc aagctacacc caggtctgtg accgccattt
     4201 cactagcgat attccctgcg cgatgacctc ccatcccatc agctaaaata atcatggtac
     4261 gtccagctct attgacatag tggttgacat agtcttggtt atttgttcgt ttctgaccaa
     4321 catctgttaa taatgaaatt tccatgtgtc agttccttcc taatccgata tcttgcgaaa
     4381 ttgactgatg aagaatccat cacttccata caattcaggt gtaatgagga tacagccgtc
     4441 tttcatgata tccttacatt catgttctag ttttacctgc tcgaactcgg gatgactctc
     4501 taaaaaggcc ttaacgactt gaaaattctc ctctgagacg atagtgcagg tgctataagt
     4561 tattatacca cctttgccta gtatttgaca aacactacct aatatttcta actgaatttc
     4621 ctgcaaggac gcgaaatctg ccgtttcttt attgtatttg atatctggtt ttcggcgcaa
     4681 aagaccgatt cctgaacaag gagcatccac caaaatctta tcaaaggaat cctggtcaaa
     4741 aaactcatgc acctttctgg catccaattt ttgagtttga acccgatctt caactcccag
     4801 acgttgggca ttttcttgaa ttaaatccaa cttgtggtcg tacaagtcca gagcagtaac
     4861 ctgacctgtc gtaaaataag aggctatatg ggctgttttc ccacctggag ccgcacaggc
     4921 atcaagcact cgctcatcac cttgtaaatt aagcgtcgga gcaaccagct gactggactc
     4981 gtcttggatg gtaatggctc catccgcaaa caaattatgc cctgcaaaat gcccctgctc
     5041 cttaaccaga ccagtggttg ctaaaaggga attattcgcc tccaacaagg cttggatttc
     5101 ctcttttcga cttaggtctg ttacacgaat actggctttg tttcgcacta acaggctttc
     5161 aaagatggct tttgctctct cctctccgta ttcttccttg agtttggcaa ctagccaaac
     5221 tgggagagaa taggcaatgg agtcacgctt gttttttcgc ttgatgctag caatatctgg
     5281 ccagccttca cgcaagatac ggcgaaggac agcgttgacc aatttttcac tgcctttttt
     5341 acggagtttg gccaattcca ctgcttcatt gaccacagca tgatctggaa tcttgtccaa
     5401 atagcggagt tggtaggcac tcatgagaag aaggacatag agccagctgt ctaactggtc
     5461 tctgtcttcg ataaagtggg ataggtacca ttccagagtc agtttacggg ctaccgttcc
     5521 atagactagc tcggtcacta agcccttgtc tgctgcagag agctgactcc ccttgaggtg
     5581 tttatttaag gcaatatttg aatatgcttg attcacaaaa acatcctcta gcactgctag
     5641 agctaaactt ctagccgttt ctactttagt caccaaatcg ttctcctaca gtcaatgtac
     5701 gtccaactcc gttgaggaag gaagcaatgt ccatcttagg cttaccagct ggctgcactt
     5761 gtttgaggga tagagcccct tcagccgttg cgacaatcaa ttctttcttg ccgatagaga
     5821 gaatctcacc tggatttccc tgaccttcta ctggtagggc ttcataaatc ttaaagcggt
     5881 cgcccttaag gaaagtatgg gtaacaggcc aggggttcat tccacgaatt tggttaaaga
     5941 gttgacgatt ggttttgttc cagtccagtt tttcttcctc tggctttata tttggagaga
     6001 aggtaacctg actcgtatcc tgcggttcag gtttgatatc accagcaata taggcaggca
     6061 gagtgtccaa aagcaaatca cgaccaacta gcgccaattt ttcaaacaag gtgccaacat
     6121 tgtcctcatc tgtgattgga atgctgcgac gagaaatcat atctcctgca tccatttcct
     6181 taaccatttc catgatggtc acaccagctt cctcatcccc ttgaatcaag gcataatgga
     6241 taggcgcacc accacggtgt ctaggaagga gggaggcatg aacgttgaca gcaaagtcca
     6301 tgctatcaag gagtttgctt gggagaaact gcccaaaagc agcagtcaca attccatctg
     6361 ctcctagctt cataagatct tccatctctg gacttccaga taatttttca ggttggtaga
     6421 tagatagtcc tgcttccttg gcagcctgct tgactggggt ttcttggata acttttttac
     6481 gaccaacagc acggtctggc tgggtcacaa cggctagaat ttcgtaacgg tcatctgtca
     6541 aaagtccttt taagactgtt gctgaaaagt cgggggtccc cataaagatt agttttgtca
     6601 tatcttctcc ttcttataaa aattgctgcg gctcatggtc aatgctgaga cggagctcac
     6661 tattttcccg ttcttgagtc aaggccaaga cctggttgag ggtcggcccc agctcatctt
     6721 ctaaacggta tttaattaaa atctggtaat gatagaggtt gtgggtacgg gcaatcggtt
     6781 ttggcgttgg ccccagaatg ggactggtct ctgacaagcc tgaccgcaaa atgttcatga
     6841 cttcataggc acgtttgaaa acctcttctt ctttcttgtg agaaagggta ataccaatcg
     6901 tgaaatagta aggtggatag ccgagttgtc gtctgattcc catttcatag gcataaaagc
     6961 cttcgtaatc ttgatccttg gcaaatcgaa tagcatagtg ctgcggattg taggactgta
     7021 tcaagacttg acctgctttt tcagcccgac ctgctcgacc tgccacctga gtcaagagct
     7081 ggaaggttct ctcagaagaa cggaaatcag gcagattcaa ggccgtatcc gcatttagaa
     7141 ctccgactag ggtaacattg ggaaaatcca aaccctttgc aatcatctga gtaccaagta
     7201 aaatatccgc ttcccctcgc ccaaactggt caagcaaggc ttggtgactg cctttctttc
     7261 gagtcgtatc cacatccatc ctcaaaatgc gagcttgggg aaagagttct gctagctcat
     7321 cataagcctt ctgagttccc gtcccatagt aacgaatact gtggctctta cagttaggac
     7381 agacctgagg aatatccttc gagaaaccac aataatggca gttcatagtc ttggtatcca
     7441 tatgcaaggt cagagaaata tcgcagttgg gacaagtatc caccgtccca cactcccgac
     7501 acatgacaaa gctagaataa ccacggcgat tgagcatgag aaccacctgc tcttttttaa
     7561 ccagacggtc ttggatagcc tctagcaaag gaggcgtaaa gtttgacgtc tcattttgtc
     7621 cgatatagtc tcgaaagtca atcacttgaa cctcagggat tgtagccaaa ggattggcac
     7681 gttgggttag acgtaagtgt tgatagacgc ctttgccagc acgcgcccgg ctctctaagc
     7741 tcggcgttgc agatccaagt accagagttg cttgattata ctgagcccgt aaaatagcta
     7801 cctctctggc atggtaacgg ggattgctgt cctgcttata agccacttca tgctcttcat
     7861 caataatcat gacacccaga tttttcagag gagcaaagat agcagatctg gcaccaacaa
     7921 caacttgggc atcgccacgc tccaccttgc gccattcatc atacttttca ccattggata
     7981 atcctgagtg aagaatggct accttgtccc caaaacgtgc tataaaacgc tcggtcatct
     8041 gaggagtcaa ggaaatctca ggtaccagca aaatagctgt cttgccctta tccagggcac
     8101 cttggataat ctgcaagtaa acctcggtct tcccacttcc tgtaatccct tgaagtagaa
     8161 agggaggttg agaactgcca atagaactca caaccgcatc acgcgcctgt ctttgttctg
     8221 gatttaactc caaaggtcta cttgcttcaa ttccttcaaa ataagcagcc gagcgttgaa
     8281 cttccttttg gactatggta acagcacctt gatccacaaa gaagttgact tgctctcgcg
     8341 agtaggactc taacaagcta gccaaggaag cgctctctgg atgagacagc agataatctc
     8401 tcagttccaa ctttttcttg gcacgtgtag aaatctcaac accttctaat tgagcatggt
     8461 caacctcata ccaagactgg gtcttgacct tcttttgatc gactgcctga tattccagac
     8521 caagcaggcc ttttctagtc aaacgcatca tttcagcttg cttggcaagg tctagtgaag
     8581 aaaaggctag cgaatcttct gaaccaaaca ggcgcactcg ttcttcctga ctcaagcctt
     8641 ccagaggata gagaatcttg tcatagctag aattcagaaa tcctggaagc atggccttga
     8701 ggatagaaat tttgtaggag aagacagatt tgcgtaactc ctcagccagc cagagttgtt
     8761 ctggcgtgag aacaggagaa aaatccagca cctctgcaat atcttttaaa tcttgctcca
     8821 tctcttctcc atctgattgg gacttcaaac caagaacaat cccttgaatc aggcgattac
     8881 ccttaccaaa aggcacatga acccgcatcc caacttccag cattccctca aattcctccg
     8941 gaatcctgta actatagggc tggtccgtct gcatcaaggg cacatctacg ataatcttag
     9001 ctagggccat cttctcacct cctccttgtc agtacattct tgcaatagaa aaaataagat
     9061 tgagtccccc caaccttaaa ttttttcacc atcttctttt tctttagcaa tttgctcttt
     9121 gattttcttt tcttcttctt ctttgcggcg tttttcttct tcgatacggc gacgcactgc
     9181 ttcacgtttt ccttctggat ctgggtgaat tgtaacgttt cctgattcga tttcttctaa
     9241 agcgcgaaga gttgattttt cagacttaaa accttgagtt gctggggcac ctgcttccaa
     9301 ttcgtgggca cgttttgctt ccaagattac gagtgaatat tttgaaggaa ccttgtcgag
     9361 caaggtatca atagagggtt ttaacatcat ttgcttgtac ctattttcta aattttatcg
     9421 ggtagttgga gattttggta acatctcctg atagtgacca atgacacgat ccacacagaa
     9481 gtgttctgct tcaatcacac atttgacacg ttcagcagct aggggcacct gatcgttgac
     9541 aatcgcataa tcatactcac gcatgagggc aatttcttcc ttggcctttt cgattcgttg
     9601 ggcaatcact tctgcactat ctgttccacg acctaccaag cgatcttgca attcatccaa
     9661 atctggtggt gtcaggaaga taaagacagc atctggaacc tttttcttga cctgaagagc
     9721 accctgaact tcaatttcaa ggaaaacatc gattcccttg tccaaggttt cattgacata
     9781 ggtcagagga gttccatagt agttgccgac atattctgcg tattccaaca tctgtccttg
     9841 acgaatcagc tcttcaaatt cttcacgagt acggaagaaa tagtcaacac cgtccacttc
     9901 tccaggacgt tgtgcgcgtg tcgtcatcga tacagaatat tgaaattggt tttcagaact
     9961 ctcaaaaatc tctcttctaa ccgttccttt tccaacccct gaaggaccag aaaaaacgat
    10021 tagtaagcct cggtctgcca ttgtgtctcc ttttagtcaa tctgtgaaat aacatttctc
    10081 tagaataatg gcaaaaagcc agattatcct ttacagtctt tctatctagt gtaacaaaaa
    10141 agcagtaatt tttcaactgc tctttcttat ttatttagca taatctactg cacgaagctc
    10201 gcgaatcacg gttaccttga tatttcctgg ataatcgaga ttgttttcaa ttttcttacg
    10261 aactttgtga gccaagattg tgactttgtc gtccttgatt tttcctggat tgaccatgat
    10321 acgaatttca cgtcctgctt gaagggcaaa gctagtttgc actccttcaa agccgttagc
    10381 aatttcttcc aaatcatgga gacgcttgat gtagctttca agagactcac tacgagcacc
    10441 tggacgggct gcgctcaagg catctgctgc agcgacgata actgctatca cgctctcagc
    10501 ttcaacatct ccgtggtgac tagcaatcgt attcaccaca actgggggtt ccttgtactt
    10561 acgggccaat tccataccga tttcaacgtg gctaccttca acctcatggt caatggcttt
    10621 cccgatatcg tgaaggaatc cagcacgacg ggcaagagcc gcattttcac caagttcgtt
    10681 cgccatgata ccagccaact tagcaacctc aatcgaatgg cgcaaaacat tttgtccata
    10741 tgaagtacgg aactgcaaac gtcccataat cttcatcaag tctggatgaa ggtttggcgc
    10801 accaatttca taagcagcag cctcaccgta ttcacgaatc ttattgtcaa tctcttgacg
    10861 gtttttctca accaactctt cgatacgagc tggatgtata cgaccatctt tgagcaacat
    10921 ttccatagtc atacgggcaa tctcacgacg aatcggatca aatcctgaca aggtcaccac
    10981 ttctggtgta tcgtcgataa tcacatcgac ccctgtcaaa ctttcaaagg tacgaatgtt
    11041 acgaccttca cgaccaataa tgcgtccctt catagtatcg tctggcagat gaactgttga
    11101 gtttgttgac tccgctacat attcaccagc gatacgttgc atagcttgaa ccaagatgtc
    11161 cttggccatt ttgtcagaac gttccttgac ctcttgctca gcttcgcgaa tgcgactggc
    11221 aatctccctg gtcaagtttt cctctgtctg agccaagata atatctcgtg cttctgcctg
    11281 agacagagca ccaatacgct ctagttctgc ttctttttgt ctttcgactt cctctaattg
    11341 ctcttcacgc gcatcaaggt ttttcgctct atcagaaata ctttgttctt tttgttcaag
    11401 tgtttgttct ttactcgtca aattgtcgtc cttacggtca aggctagtag ctctctctgt
    11461 caaacgactt tcgatttgtt tgagttcttg acgttctgat ttgaattcag cgtccacttc
    11521 ttcacggtat tttctggctt cttctttggc ctccaatagt gcttcttttt taagagactt
    11581 gctttcacgt ttagcttcat taacaagtaa atccgcttca cgctcagctt gtccacgtaa
    11641 attagttgct tcttgttcag catttaaaag catcaactcc gcagcttcct gagatgattt
    11701 catcttagct gagatgctga catatccaat gactaaacca atgatgacgg caaaaacagc
    11761 aatcgcaagc gacatgattt ccatgttttt acctcatttt attgttattc cgaatgacat
    11821 acattctttt acattctacc ataaaaaagt gattttcaca aacctaaaat agaatatgtt
    11881 ttggggaatt tggaatacat ttgccaaaat aaacttgttt tttagaaata gtagtgttag
    11941 tagagacttg agaaaaagcc tacctttcag tagacttagt ttgtttctat tctaatcggc
    12001 actcttccaa aattttgctc tgctatactt ggatttccta gttggtaaat ctggtctgct
    12061 ttttgggtca tagcatccca aggttctttg ccaattcggc tgactagact gacctgacct
    12121 ttcaaagact tgagatgttg cctgcctttt tcagtaaatc caaggacatg aatggcttct
    12181 ggcaagacat tttctctagc ctgcaccaaa atataggtca ataggcgtct gacacgcgcc
    12241 ttggtgtaac gtttggtcgc aaccgcctcg accaactctt ctacagactg ggctgtttta
    12301 atagcttctt taatgcgcac agccatttct tgattgacct gatagatggt ggttaggtcg
    12361 ggatttgaca agatttgata gcggagcaag ggaaaatagt cttcccagat caccttactg
    12421 gcctgctcaa atagggcaac agaaggcata aaacgttcta agaaatcttg gtccttctga
    12481 tgttgacgga gggctgtcgc cgaggcaaag tccacatctt tattcacaga atggtaacct
    12541 gccccctgac gctgaatcgg atgcagcttg atatttcgtc ctgcaaccgc cttggcatag
    12601 gccagagcaa gaacatgatt gggggtatta cctgaaaaat caagaccagc aaattcctgc
    12661 cacatagctt gggttttctg gggataggaa agggaatcag gcagattttc cacaaatttc
    12721 tccatctcag cacctttctc tgtgtataag tcagcgattt tctgataatc tcgaacttcc
    12781 tctgtcccaa aaactagact atcaatgccc aagcgatcca agatatccac agctccttga
    12841 ccaaagaaat cagctgcctg aacactgact aaaaagggca attccactac caagtctgcg
    12901 ccattttcca gcgccatctg ggcccttgtc cacttatcca caatagcagg ctctccacgc
    12961 tgcatgaaat tccctgacat ggcaacagtt ttcagtccct ctgcctgatc cagcaggtat
    13021 ttatggccat tatgaaaagg attgaactcc gcgataatac ctgttatggt catgctaatc
    13081 tcctacttct gcgccacaaa aaaccaacgg gtgctagttt ctgttggctc cttatcctca
    13141 aagtctgcat agagtttgaa ggacttgaat ccagcctgtt ccagcaagat atcataggtc
    13201 aagatctcat aggtcctctc ctcatgtact tcatcgtggc gactaaagga accgtcagcc
    13261 tccttgataa agaaagtcag ctcatgcacg atggagtgag gagcttcgtc ctcatatgta
    13321 tcccaaagca tggcaaaatc ttccgcattt tcatggtagg aatagccagg gaatacttca
    13381 tctgtctggt aggtcgagtg cacgtcaaag atgaaaactc cctcttcatt cagcgcattg
    13441 tacacgtcct taaagacgtc ccctacttcc acctcatcct gcatatagca gatagagtcc
    13501 gaataacacg tgacaaaatc gtatttccct gccttggaca aattcagcat attaccttct
    13561 ataaaagcaa tcttttgctt ggctgaagtt gctctcttct ccgcaatctt caacatatcc
    13621 gcactcaagt caagtccagt cacatcaaaa ccagcctgag agaagcgcac tgattgaatt
    13681 cctgtcccac aagccaattc caagagtttc tttctctcct tggtcttagg caaatgacgc
    13741 agagaaaaat tcgtccattt gtcgtataaa ctatcgtcca tgaccgcatc atagaccgcc
    13801 gcaaaggttt cataagtcgc cataatcatg atactaagag ctccatggta aacaccacta
    13861 gccctttacc tttctatcaa tttttctaaa ataagcaaag aaacccagtt gactacaact
    13921 gagttcatct tctaagcaag agcttctgaa atatctactg aattcgcctc atgccatagc
    13981 ttctctagat tataatgggc acgcatttct tctgaaaaga tatgcacgac aacagcaccg
    14041 aggtccagta agacccagcc tccagctgca tcgccttcga catggctacc tttaaagcct
    14101 gcttgagcta ctttttcacg gatattagct gcgatagcgt ccaactgacg gctattcatt
    14161 gagctagtga tgacaaagta gtccgtcaca ctagtcaaat cttgtacatc aagtgcgagg
    14221 atatcctccg cacgtttctc atcagccgct ttcacgacta gttctagtaa ttctttttcg
    14281 ttcatttaat cctcttttta gaaaatatgt ttgtaatcta ggacatctgc aaagcgctcc
    14341 tcccaaatgt cctcataaaa ttcattaatc gtttctgctg gaatgtcatc cccatcaaag
    14401 gttgtgacag caccttctgg aacaataagc tgatagccat attcaaaggc aaccttgaca
    14461 gaggtatcca cacaatattc tgtctgcata ccacataaaa ctaatttttc aatcccctgt
    14521 ttatccaagt attcttttaa gccagtttct ttgaaaatac tgttatactt cttctgaaag
    14581 accttttcag caggttttcg atttaaaagc gcagataact gccaatcttc tgatgtttga
    14641 gcttcagagt tctcaatatg ttgaacatag ataatttcaa tattcttgct tctagcctgg
    14701 ttttgtaaat aagaaatttt ttccaataga ctttttgtct ggaacccagt ttctactaaa
    14761 acattctgaa catcaatgat tataaaagcc gtcttcattt agtcctcttt caaatagtgc
    14821 acaaaggcgt tataggtttc aagggtttgg ggatagatgg ggaatccctg atgagctaga
    14881 tactccacgg tacgagctgt ttcgtaggcc accgccttat tgagcgatag acttgcaatc
    14941 tcacgcgcca catctactcc aggaaaggat cgattgtgct cgatatagtc tgcgacgtag
    15001 atgaccttat ctaggtctgt catttgacca gctccgactg tatgaatttc aatggctcgc
    15061 agaatttcag aatcatgcaa atccaaatct tcctgaattt tgtaaattcc gaccatacca
    15121 tgccagacat tattgcccca gtttttgagg tcagggtcta gctggtaacg gtcaatcaag
    15181 gctagaaatt cctgatttga caacttttta gcatagtcat gaagaagacc tgctagactt
    15241 gctttctcaa catctacacc aaagcgctga gctaactcca tagcggcacg ctccacacct
    15301 agacaatggg ttagacgttt ctcaggtaga agctctgcca ttttttccaa caaggcctca
    15361 cgggagcagt tgatatagtc ttgataggac atcagtagag cccctccttc tcgatgtagt
    15421 ctagcactgg ctgaggtagg agaaagttgg gtttccgacc ttgggcaatg aagtcccgca
    15481 ccatgctgga cgagatatcc atgagcggta cgtccaccca gataactgga taggaagttc
    15541 ctgccttgta gcgtggacgc tgaaccccca caaactgaac catgtcaacc agttcatcaa
    15601 ttcggtacca cttaggcaga tagtcaacca tgtcggcacc gatgataaag taataatccg
    15661 tatctggatg ttgctctgtc aagattttca tggtgtcgta ggtgtaggaa atacccttgc
    15721 gctccaactc aatggtttca atgactaggc cgtcaatccc ctcaattgcc aactcaagca
    15781 tcttgagacg atggtgttca gggatggttt cctttttatc aacgtgagga ggttggtatt
    15841 caggcatgag aagaacttga tccagtccca actgttgccg tacttgatcc gcaacaatga
    15901 gatgggcatt gtgaacaggg ttaaaattcc cccctaaaat cccaacttgt ttgcgttttt
    15961 tctccttgat ttctggctcc aactctacct tggtaaaggg agtcaatagt tcgattgtca
    16021 taggctagtc ccctttattt ctctataaaa acagttattt ggagtttcgg tcttagattt
    16081 ctttgacttt cttagaaatc ttgcgatttt ctttcttgct agattgttta aacaaaatca
    16141 agatgcgtcc tattttttgg actgtatcca caccgatttc ttcttccaaa atttcagcta
    16201 cttcgtggat gttttcatct gtgttttgta agagagtaac cttgattaat tcacgcgcat
    16261 caagagcttg acggacgctg gttttgattt ggtcgttgag tccatttttc ccgatttgga
    16321 tgataggttt gagggtgtgt gcctggctgt tgaggaaggc acgttgtttt gatgttaatg
    16381 acataatttt cttccttgtt tttggatagt tattttaggt ggtgagggac ggtcggaact
    16441 aattttccaa agatttcatc tttgaaaaat ggatttcctg acctcacaat tgagccttgg
    16501 tctcaattgt gccccttgcc aatctacaga ttggcaatca caccacggca ataactatcg
    16561 ctatatgagc tcactttgtt cgctcagcga ttttgtttta aataattgct tttcgtgtga
    16621 cgacggcgac gccttctggt gcccagacgg cgacttttgc tatgcctgtt acacgaatcc
    16681 agcctaggcc tgagatgact aggtctgtct tatctttaat ggtaaagaca tgctggacta
    16741 gccttgggaa atcttctttt tccttgctat ttggtggtgt cagaagagtt cccaggtgct
    16801 tatcgtagaa agcactagct ccttcaagct tgctacgatg gagtttgagt tcattatcaa
    16861 agaaagcagt aaatccttgc ttttctcctg ctataaagtc aaagcgtccc aaaccaccta
    16921 aaaatagggt ttgctcagga ttaagctgat aggtcttagg cttgatttcc tttttaggac
    16981 tgacatactt gaggtttttg gccgtcaagt agtgagccat ctggtggcgg tggataattc
    17041 ccggcgtatc gtaaatataa gatccgtcgt caagcggaat ctctattttg tccaaggttg
    17101 tccctgggaa gcgtgaagta gtgatgacat tctgatcacc cgtgatttct tggataatag
    17161 cattgattag agttgatttt ccaacgttgg tcacaccgac cacatagaca tcgcggccct
    17221 tacggtagtg ttcaatcttg tcaatgactt ccttaatggc atgtttattt tgtgctgaag
    17281 ttaggaccac atcgactgga cgaagacctt cttcatgggc acgtttcatg agccactggc
    17341 taatcttacc agacttaact gacttaggaa ggatatcttt tttatttcct accaagagga
    17401 catcattgcc cgagacgaaa cgtggtaaac ctgggatgac agatccatta aaatcaaaga
    17461 tatcaataac attgaccact aaagcatcac tgtctcccac ctcgtgcaag agcttgagga
    17521 aatcatcgtt cgtcaactgg acatctgtga tttcattgta gtggcggaga cggaaacagc
    17581 gttggcaata gacttcgcca gtctccaaac ctttttcaag tgccgactgg ggggtaaaac
    17641 caagaccagc tttatctgtc gtctgaatgg ttgctccaca accaatacag agaatttctt
    17701 ccatagttaa attccttttt tatatgtaat cggtccgtac ttttcagtga tttttctcat
    17761 aacacgacgc tcacgagttc ggttaatctg cgttttgatt gagtcatgtt ggaccaaggg
    17821 tttgactaaa attgaccgaa tccctgcacg gtgggctgct cgtatatctg tcatgagctg
    17881 gtcaccaacc atgaccactt cctttttgtc atagtggaat tccttcatag cacggtcaat
    17941 accaaatgtg aagggcttca aggcccagta aacgtaatca atcccaaatt tctcaactgc
    18001 tcgttgaacg cgttttttgg tgttatttga cactacgata atgccaatac ccgcgtcccg
    18061 aaggtcatgt agccattgct tcatctctgg cgttccatca gggttgttcc aagcaatgag
    18121 ggtattatcc aaatcgacca aaacagcctt gattccctgc acctgcaggc ttgggactgt
    18181 cagatcatag actgcttcca cagcaaaatc tggtatataa ttttcaatcg ccattctggc
    18241 tccttttctt aacttttttt cgcaattttc cttagtaaca aggataaaac aatccacaaa
    18301 cctgcactag ccaaactaat atagagccaa gcatggggct catctgttaa aggtaaggga
    18361 acattcattc cgaaaaagcc tgtcacgact gccaaaacag ctagcaagac tgaaatgata
    18421 gtcaaggttg tcaaattgtc attcagatta ttgtttagaa tattgttgta agaggctgaa
    18481 agctgctgta aaatctgaga gattaggtct gtcatggata ccagctgatg agcctcaatc
    18541 atggcatcat caaactgttc tctctcaatc tcatcaaaac tacgatacaa ggcatgacct
    18601 tgaatatgct ctaacaaaat ccgattttgt ttggcagctg ccgtcagata aaccatacca
    18661 gtctccaaat cagacagggc aaagaggttt ttcttggtag ttcgctggcg caagaggtca
    18721 ttgacctcat ccctactctt gtccatctgc tcaatgacag gatagtaggc attgctgatg
    18781 atttccagac tggcaaagag aaacttataa atcgaaagcg tgtcatggct ctccagataa
    18841 cgagtcatct gttcaatgac ataggcgttc ttggtattac taatggtaat caggcgacga
    18901 tgctcgacaa taaaggtcat gggaaaagtc tcatagtagg ccttgtcctt ttttacgtct
    18961 aggacattat agataaaggt aaccgtccca ctttcacggt ggtaatccat gtgggcgcgc
    19021 tcgtttctat ccagtgcgta ttcaatggtt tccttgtcca aaccgtaaat ttcagaaagg
    19081 tcttctagtt tattcaactt tcctaggtct aggtctatcc aggtacaacc attgcccaac
    19141 tgcttttcta aaaccatctt ttctccttat taaactccct ctattgtacc acaaattact
    19201 taaaataaca ggtctagtct gtgcgtgaga aattgctaac aactgtgata tttcggttag
    19261 ggacaaagtg aagggcttgc tcctcgctac gaagctgtgt cgtacgaatt cccacactga
    19321 caaccttacc cgatacagta atcggtccat ttgtcagaac gacctcatct cccacatcca
    19381 gttgacgttc aaagaggatg aaaaagccat tgatgacatc agacagaaag ccttgggctc
    19441 ccataccaat cgctacccca gcaataccag ctccagccag caaactagaa actggcaaac
    19501 ctaaaatcga caaaatgcag tagagtaaaa agaaatatag cgtataatta aacacatttt
    19561 ctagtaaacg tgagatggtt ttttggcgtc cgacatcatg acgagacatt tttagagaag
    19621 gtttgacaat tctctgcacc atggtatgaa gcattttttt agcaatataa aatacaatca
    19681 aaagcagtaa aagagaaatg accttggtta gaatattctc gataatggtt gtcacatcta
    19741 gcttttcaat ataagcctga ataaattttt gcatataaaa ctcctttatt tcattatacc
    19801 atattttcat cagtctcatt ctccataaat attcaaaaaa tagacagaaa attcttgatt
    19861 ttgtctatca tttatactat aatcataatc actacacaaa aaggagatta ttatgaaaag
    19921 aatcattcat gcttggaata aggcaagcct tgtcaagcgt atcttgattg gtatgctttg
    19981 tggggaatcc taggactgac ccttcctaat ctctcaggga ttgggctact cggggattta
    20041 ttcgttggag gtctaaaagc tgttgctcct atcctagtct ttgccctcgt tgccaatgcc
    20101 ctttcccaac atcaaaaggg acaagatagc aatatgaaaa ctgttgtttt cttgtatatc
    20161 ctatgatagg gactttcgcc gctgctcttg tagctgtact agcaagtttc atcgtcccta
    20221 ttgaaattac cctaaatagt gccaatactg aaattgcacc accagatggg attgggcagg
    20281 tcctcagcaa cctcttgctc aaactggttg acagcccagt caacgccctg tttactgcta
    20341 actatattgg aatcttatct tgggcagtca tttttggaat cgctatgaga gaagccagta
    20401 aaaatagtaa agaattgcta aaaactatcg ctgacgtgac ttctaaaatt gtcgaatgga
    20461 tcatcaatct ggctccattt ggaatccttg gtcttgtttt taaaaccatt tctgacaagg
    20521 gagtcggaag ccttgccaac tacggtattt tattggttcc attagtaacg actatgcttt
    20581 ttgttgcccc tgtggtcaac cctttgattg cttcttcttt atgagacgca atccttactc
    20641 tctagtttgg aactgcctcc gtgtcagcgg tgtgacagcc tttttcactc gtagttctgc
    20701 gactaacatt cctgtcaaca tgaaactctg ccatgacctt ggactcaacc cagataccta
    20761 ttctgtttct atcccactcg gttctactat caatatggct ggagtagcga ttaccattaa
    20821 ccttttgacc cttgctgcag ttaacactct tggaattcct gttgactttg ccacagcctt
    20881 tgtcctcagt gtggtagcag ctatctcatc ctgtgatgct tcaggtattg ccggaggttc
    20941 cctccttctt atcccagttg cttgtagcct tttcggtatt tctaacgata ttgccataca
    21001 aattgttggg gttggttttg tgattggtgt catccaagac tcatgtgaaa cagcccttaa
    21061 ctcttctaca gatgtcctct ttaccgccgt tgccgaatac gcagcaaccc gtaaaaaata
    21121 actcatcaag gcaagcctgc tcatgtcttg tcttttacgc ttttattcta acttattagg
    21181 aaattcttat gtctattagc caacgtacga ccaagctcat cttagctacc tgtcttgcct
    21241 gcctgcttgc ttattttctc aatctttcgt cagcagtttc ggctggaatt atcgctctct
    21301 tgagcctatc tgatacgcgt agaagtactt taaaactggc tcgcaatcgt cttttttcta
    21361 tgcttctagc tctggctatc ggtgttctag cttttcactt gagcggattt catatctgga
    21421 gtctcggcct ctatctggcc ttctacgttc ctttagccta caagatgggc tgggaaattg
    21481 gcatcacacc aagcactgtt ttggttagcc atctcttggt tcaagagtca acctctccag
    21541 accttctagt caatgaattc cttctctttg ctattggtac aggatttgcc ttgcttgtta
    21601 atctctatat gccttcacga gaagaggaaa tccagcacta ccacacgctg gtggaagaaa
    21661 agttaaaaga tatcctccag cgcttcaaat actatttatc cagaggagac ggacgcaatc
    21721 gagcacagct ggtagcagaa ttagacacgc ttttgaaaga agccctcaga ctggtctatt
    21781 tggatcactc tgaccacctc tttcaccaga ccgactacca tatccactac tttgagatga
    21841 gacaacgaca aagtcgtatc ctgagaaaca tggcccaaca gattaacact tgtcaccttg
    21901 ccgccagtga aagcctgatc ttagcgcaac tcttttcaaa aattgcaggt caactgagcc
    21961 agaccaatcc tgcttctgat ttgctagatg aaattgaacg ttatctggaa gtcttccgga
    22021 accgcagtct gcccaagaca agagaagaat ttgaaacccg cgccaccctt cttcaactcc
    22081 tacgtgaagc caaaaccttc atccaagtaa aagttgattt ttaccaaaaa tatggacagt
    22141 aaaaaataaa accactaaaa aacagagctt gccagcattc ttgaaaagta gtataattat
    22201 tgcatgcgca atcatcttgt gacgcagaga ctgcccgtta atggactttc ttctatatta
    22261 tgactctaaa aagaaaggag acactatgac ctatttggaa aaatggtttg acttcaatcg
    22321 gcgtcagaaa gaaattgaaa gtctcttgga agagaccatt gcccaacaga gcgagcaaag
    22381 tctgaccttg aaagagttct acctgctcta ctatctggac ttggctgaag aaaaatctct
    22441 acgccagatt gacctgccag ataagcttca tctgagcccg agcgcagttt ctaggatggt
    22501 ggctcgcttg gaagctaaaa attgcggtct actcagtcgc atgtgttgcc atcaagatag
    22561 acgctctagt tttatctgcc tgacaaatga tgggcaaaag acactggcct cgctacaaaa
    22621 gactgtcgaa gaaagcttgg aagcaggttt ggatttcttg atttaagatg attttaaaaa
    22681 aagttgcgtg cgcaatcatt tttcttgaca ttctctttta taaggagtaa aataaagtta
    22741 gcattaaaca aaggagtttt aaatatgatt gaaattacct atatagatgc cagcaagaac
    22801 gaaagaactg tgactttcga gtcttatgaa gactttgaac gttcgcaaca agcttgcctt
    22861 atcggcgtcg cagactacta ccctgtccaa aaattaactt acaagggtca taatttggac
    22921 taccatggga cttatggaga tatcttcttc tatctcatga aacaagattt aagccaatat
    22981 aactaaaaaa aggagaaata caatggcaaa agcaattaca gatgcaacat tcgaacaaga
    23041 aacaaaagac ggtttggtct tagtagactt ctgggcaact tggtgtggtc catgtcgtat
    23101 gcaaggtcca atcttggaca aattgtctga agaactttca gaagatgtct tgaaaatcgt
    23161 taaaatggac gttgatgaaa atccaaacac agctcgtgct tttggaatca tgtctattcc
    23221 aactcttctc ttcaaaaaag acggccaagt tgtcaaacaa gttgcaggtg ttcacacagc
    23281 agaacaaatc aaggccatca ttgctgaatt gagctaatca aacgagagac caagtacttt
    23341 ctttggtctc ttttttcttg ccctttgcca tttttcaaaa aatatgctag actatagtag
    23401 attgaaacta gaatagtaca cctctacttc taaaacattg ttagaaatcg atttgactgt
    23461 cctgatcgat ttgtcctgtt cttatttcat tttactatat aagtagaata ttacgatgtt
    23521 tgggatatgc catcgctaaa aaaactcgat ttggtatttt ttagctccct aatgggagct
    23581 ttttgcgtgc tctgaacatt tcccattttg gaaggagtac tatgaaacgt caatcagcct
    23641 tggtcgtctt tagtggtggt caagattcaa caacctgcct tttctgggcc atgcaacact
    23701 atgaaacagt cgaagctgtc acctttgcct acggccaacg tcatcacctc gaaattcaaa
    23761 ttactagaga aatcgctaag gaacagggca ttcgtcacca tatcctcgat atgtctctgc
    23821 tgggacaaat cactgctcag ccagactttg cgacgattca tatttcctac attcctgaca
    23881 agctctgtgt cgagtcaaaa tccctcaaac tatatctatt tagctaccga aatcacggag
    23941 atttccacga aaactgtatc aacaccatcg ggaaagactt ggtcaacttg ctagaccctc
    24001 gctatttaga agtctgggga aaattcactc cgcgcggtgg catttcaatc gacccctact
    24061 ataactacgg taagcaagga actaagtatg agggcttggc agaacaacgc ctcttccaac
    24121 acgaccttta tccagagaaa attgacaacc gctaaagtca tactcaatga aaatcaaaga
    24181 gcaaactagg aagttagccg caggttactc aaagcagtgt ttgaggttgt agataaaact
    24241 gacgaagtca gctcaaaaca ctgttttgag gttgc
//
LOCUS       DAVHBD010000034        24188 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000034 DAVHBD010000000
VERSION     DAVHBD010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.034"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..146
                     /locus_tag="VVK04_001456"
     CDS             <1..146
                     /locus_tag="VVK04_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990100.1"
                     /translation="KLLHLPSYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCS
                     CFN"
     gene            complement(353..2611)
                     /locus_tag="VVK04_001457"
     CDS             complement(353..2611)
                     /locus_tag="VVK04_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU3990101.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TLPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDDIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLGRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2840..3070)
                     /locus_tag="VVK04_001458"
     CDS             complement(2840..3070)
                     /locus_tag="VVK04_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU3990102.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3260..3943
                     /locus_tag="VVK04_001459"
     CDS             3260..3943
                     /locus_tag="VVK04_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU3990103.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3943..4677
                     /locus_tag="VVK04_001460"
     CDS             3943..4677
                     /locus_tag="VVK04_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU3990104.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKAYAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4831..5688
                     /locus_tag="VVK04_001461"
     CDS             4831..5688
                     /locus_tag="VVK04_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU3990105.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5830..6702
                     /locus_tag="VVK04_001462"
     CDS             5830..6702
                     /locus_tag="VVK04_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU3990106.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKNKLV"
     gene            6984..7667
                     /gene="rpiA"
                     /locus_tag="VVK04_001463"
     CDS             6984..7667
                     /gene="rpiA"
                     /locus_tag="VVK04_001463"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU3990107.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTIDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7681..8892
                     /locus_tag="VVK04_001464"
     CDS             7681..8892
                     /locus_tag="VVK04_001464"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU3990108.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLSVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8894..9436
                     /locus_tag="VVK04_001465"
     CDS             8894..9436
                     /locus_tag="VVK04_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU3990109.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9452..10261
                     /locus_tag="VVK04_001466"
     CDS             9452..10261
                     /locus_tag="VVK04_001466"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU3990110.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10737..11717
                     /locus_tag="VVK04_001467"
                     /pseudo
     CDS             10737..11717
                     /locus_tag="VVK04_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11742..12254
                     /locus_tag="VVK04_001468"
     CDS             11742..12254
                     /locus_tag="VVK04_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU3990111.1"
                     /translation="MSAQITINYKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGHQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12908..13618
                     /gene="deoD"
                     /locus_tag="VVK04_001469"
     CDS             12908..13618
                     /gene="deoD"
                     /locus_tag="VVK04_001469"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU3990112.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13641..14165)
                     /locus_tag="VVK04_001470"
     CDS             complement(13641..14165)
                     /locus_tag="VVK04_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU3990113.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14218..14454)
                     /locus_tag="VVK04_001471"
     CDS             complement(14218..14454)
                     /locus_tag="VVK04_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU3990114.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14522..15442)
                     /locus_tag="VVK04_001472"
     CDS             complement(14522..15442)
                     /locus_tag="VVK04_001472"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU3990115.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15632..16035
                     /locus_tag="VVK04_001473"
                     /pseudo
     CDS             15632..16035
                     /locus_tag="VVK04_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16251..16832
                     /locus_tag="VVK04_001474"
     CDS             16251..16832
                     /locus_tag="VVK04_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU3990116.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16829..18106
                     /locus_tag="VVK04_001475"
     CDS             16829..18106
                     /locus_tag="VVK04_001475"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU3990117.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILVPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18124..18786
                     /gene="deoC"
                     /locus_tag="VVK04_001476"
     CDS             18124..18786
                     /gene="deoC"
                     /locus_tag="VVK04_001476"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU3990118.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18773..19162
                     /locus_tag="VVK04_001477"
     CDS             18773..19162
                     /locus_tag="VVK04_001477"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU3990119.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NVSYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19253..20305
                     /locus_tag="VVK04_001478"
     CDS             19253..20305
                     /locus_tag="VVK04_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU3990120.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDIANKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20449..21984
                     /locus_tag="VVK04_001479"
     CDS             20449..21984
                     /locus_tag="VVK04_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990121.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21977..23035
                     /locus_tag="VVK04_001480"
     CDS             21977..23035
                     /locus_tag="VVK04_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990122.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23038..23994
                     /locus_tag="VVK04_001481"
     CDS             23038..23994
                     /locus_tag="VVK04_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990123.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            24079..>24188
                     /locus_tag="VVK04_001482"
     CDS             24079..>24188
                     /locus_tag="VVK04_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990124.1"
                     /translation="MKLSYDDKVQIYELRKQGYSLEKLSNKFGINNSNLR"
BASE COUNT         7046 a         4363 c         5481 g         7298 t
ORIGIN      
        1 ataaactttt acatcttcct tcctactcac ctgagtacaa tcctattgag aaaacatggg
       61 ctcatatcaa aaagcacctc aaaaaggtat taccaagttg caataccttt tatgaggctc
      121 ttttgtcttg ttcttgtttc aattgactat agcagattga aataagatga gaacaaatcg
      181 attgggaaag taaaattaat ttctataaat gttttagcaa ttgtttcgta ctatttcaga
      241 ttcagtctac tatatatcat aatggacaaa gggcaagctg tcaagaaatt acagttattt
      301 tagtaaaaaa agaagcagaa aaatttcatt ttctactcct tttctatagg atttattttt
      361 ctttttcaga acttttaact tcagcttttt tggcagattt aatctgaatg tttcccttgc
      421 tagtcataac tgctttgaga tctttttcgc ttggattttc aaggtagtag tcagtgattg
      481 tgtcctcaat atagtcttga atagtccgac caagtgggcg tgctcccatt tttggatcat
      541 aacctaggtc aaccaacttt tccttgacct tatcagttac atccaaacga atgttgttgc
      601 tagagaggcg cttgttaaca tctgctagca tgagctcgac aatctgaagg aggttatcct
      661 tgctgagagc cttaaattcg ataatgtcat caaaacggtt cataaactct gggctaaaga
      721 agttaccgag ttcaccgagg acagaattgg tacgtccttc tctagcagca ccaaatccaa
      781 cgctagcttc ggtctttcct gtacctgcat ttgaggtcat gataatgatg gcatccttga
      841 agctaacggt gcgtccttgc ccgtctgtca aacgaccatc gtccaagact tgaagaaaca
      901 tgtgcataac atctgggtga gctttttcca cttcatcgag aaggatgaga gaatatggat
      961 tgtggcgaac tttttcagtt aattgaccag cctcatcata gccaacataa cctggagggg
     1021 cgccgaccaa cttagccaca ctatgttttt ccatgtattc actcatatca aagcgaatca
     1081 tactatcagc agaaccaaaa agttcgatag ccagttgttt ggaaagttct gtcttaccga
     1141 caccagttgg cccaacgaag aggaagcttc cgattgggcg gttaggggta ccaagtccga
     1201 cacgattacg gcgaatagcc ttggcaatct tatcgactgc atcatcttgg ccaataacat
     1261 gagacttgag atcttcggct agatggatga gttgagattg ttctttctct ttcaaatcac
     1321 caacagggat attggttttc tgctcgataa tgtgctcaat agttttctcg ctgatgatag
     1381 gagtatcctg gtctgtgatc tttttctttt gcatttcctt atacttggca atctggtcgc
     1441 ggaagtaggc cgccttctca aaatcttctt ctcgtgtagc ttgagacttg agattttcag
     1501 cctcaatcaa gcgctgatca attactttag gatccacaaa attcaaggtc aagttcatct
     1561 tagaaccagc ttcatctagg aggtcaatgg ccttgtcagg caagaagcga tcttggatgt
     1621 agcgattgga aagagttgca gctgcttcaa tcgcagcatc tgtatattga acgtggtggt
     1681 aatcttcgta tttcttttga atccctttga gaatagtgat tgtttcgtcc accgttggtt
     1741 catcgacttt aacaggctgc atacgacgct cgagggcagc atccttttca atgatacggt
     1801 attcattgag ggtagtagca ccgactagtt gcagttctcc acgagcaagg gctggcttga
     1861 ggatatttcc tgcgtccata ttaccatcac tcgcagaacc agcaccaaca atttcatgga
     1921 tttcatcgat aaagaggatg atgtcttcac gtttgcgaat ttcttccatg agtttttgca
     1981 tgcgttcttc aaattgtcct cgaatccccg ttccttgaac taagctaacc acatccagac
     2041 ggatgacttg tttaccttgg agtttatgtg gcacatcgcc atcgacaatt ttctgagcta
     2101 gaccttcgac aacggccgtt tttccgacac caggttcacc gataaggaca ggattattct
     2161 tggttctacg attgagaatc tcgatgacac ggataatctc atcgtcgcgc ccaataacgg
     2221 ggtcaatgtc tccacgacgg gcaatttcag ttacattaat accaaattct tccagcaggc
     2281 ctttttcttg gctaggtggc agagtttgag cagatccacg attttgggaa ccataaccgc
     2341 cgtttccacc gtaacctcca cctgattggg ttgggggaat aggaggagta ttgctagaag
     2401 gtctgaaatt gtttagatca ttgaagaaat caccaaaggg atcgaagtca cgattgttca
     2461 gatccgtcat acctttgaag aggctattgt taggatctgt tttgataatc ttatagcagt
     2521 tttgacagag gtcaatttgt ttttgttttc cattgagatt ggtgtaaaga tgaattgttg
     2581 agtcgttaat tttacagttt tgacaaagca tacatctacc tcatttcttt ctttagcctg
     2641 acttgtttaa aggtcaaaaa tagtcaaatt ctatactctc attataacag gattggggtg
     2701 taaagcaagt aaaaagattg aagctttgag aagttgttac aatgaaaatt tttgtgaatt
     2761 tggactataa aaaaatccta tttgtgagac aaaaaggatt ttacttagac atgcagggac
     2821 aatcccagct tgttttagat tagtagagaa gttcgtaaat ttccattgcg attaagtcaa
     2881 tgctatcaaa cgtatacgtt tcgcgatctt ctacgtcacg aagggtaaag attgggccgt
     2941 tttcttcgtc gtggctgtac gcaacttctg caacaacaac tccttcgcgt tcaaaattac
     3001 gttttaaatt tccgccatcg tttgccattg cttcaaggcg gttgatgatt ctaaccaaat
     3061 gtgattccat tttgattctc cttcatttct tatcgttact attttaccat aaaggaggcc
     3121 aacttgacta gaaaaaacta agatttctcg ctaattctgc tagtttaaag atttttaaat
     3181 aaattggata aaaaatttaa attttaattc aaaacatgtt ataatcatac agtattctat
     3241 tttagaaagc agtgtgacta tgaatttttc ttttttacct aagtatttac cttattttaa
     3301 ctatggggct gttgtgacga ttcttatttc tatctgtgtt atctttttgg gaactatttt
     3361 gggtgttgtc ttggcttttg ggcaacgttc aaagtttaaa ccgcttgttt ggttggccaa
     3421 cttgtacgtt tggattttcc gtgggacacc gatgatggtt caaattatga ttgcctttgc
     3481 tcttatgcat atcaatgctc cgactattca gattggaatt ttaggtgttg atttttcgcg
     3541 tctgattcca gggattttga ttatctctat gaatagtggt gcttatgttt cggagactgt
     3601 tcgtgccgga atcaatgcgg ttccaaaagg tcagctagag gcggcttatt cgctagggat
     3661 tcgtcctaaa aatgcgatgc gttatgtgat tttgccacaa gcaatcaaaa atatcttgcc
     3721 agcattgggg aacgaattta tcaccattat caaggacagc tccctcttat cagctattgg
     3781 ggtcatggag ttgtggaatg gggctacaac agtttctaca acaacctatc tacctttaac
     3841 accgctttta tttgcagcat tttattactt gattatgacc tctattctga cagtagcctt
     3901 gaaagctttt gaaaaacata tgggacaagg agataagaaa taatgacaga aaccttgata
     3961 aaaattgaaa atttacataa atcttttgga aagaatgaag tattgaaggg catcaacctc
     4021 gagattaaaa gaggagaagt tgtcgttatc atcggtcctt cagggagtgg gaaatctacc
     4081 ttgcttcgct ctatgaattt gttggaggaa gcaaccaagg ggaagcttat ctttgaggga
     4141 gtcgatatta cggacaagaa gaatgacctg tttgccatgc gtgagaagat gggcatggtt
     4201 ttccaacaat ttaacctctt tcctaatatg actgtgatgg aaaatattac cttgtcacct
     4261 atcaagacta aaggtgaaag cagggaagtt gctgagaaga gagcccaaga gcttttggaa
     4321 aaagttggtt tgccagataa ggcatacgct tatccacaga gtctgtcggg tgggcaacaa
     4381 caacggattg ccatcgcgcg tgggttggct atggaaccag atgttttgct ctttgacgaa
     4441 ccaacttcag ccttggatcc tgaaatggta ggtgaggtat tggctgttat gcaagacctt
     4501 gccaagtcag ggatgactat ggttatcgta acacatgaga tgggatttgc ccgtgaggtg
     4561 gcagatcgtg ttatctttat ggcagacggt gtggttgttg aagatgggac acctgagcag
     4621 atttttgaac aaacccaaga acaacggact aaagatttct tgagtaaggt tttataatct
     4681 attttaaaat ttcaagacaa gattagtgaa aagttcaacc agagcttttt cttatagttt
     4741 gaaactatag gataacctag gaaagaagtg ttagagggca ctagcagttt ttggtataat
     4801 ggaagatatt tgaaagaaaa gagaagtgat atgacacaga ttattgatgg gaaagcttta
     4861 gcggccaaat tgcaggggca gttggctgaa aagactgcaa aattaaagga agaaacaggt
     4921 ctagtgcctg gtttggtagt gattttggtt ggggataatc cagccagcca agtctacgtt
     4981 cgcaacaagg agaggtcagc tcttgcggct ggttcccgta gcgaagtagt gcgagttcca
     5041 gagaccatta ctcaagagga attgttagac ctgattgcta aatataatca ggatccagct
     5101 tggcatggga ttttggtcca gttgccatta ccaaaacata tcgatgaaga ggcggtttta
     5161 ttagccattg atccagaaaa ggatgtggat ggtttccatc ccctaaacat gggacgtctt
     5221 tggtctggac atccagtcat gattccctcg acacctgcag gaattatgga aatgtttcat
     5281 gaatatggga ttgacttgga aggtaaaaat gcggtcgtca tcggtcgttc aaatatcgtt
     5341 ggaaaaccta tggctcagct tcttttggct aaaaatgcga cagtaacctt gacccactca
     5401 cgaactcata atcttgccaa ggtggctgct aaagcagata ttcttgtagt cgcaatcggc
     5461 cgcgccaagt ttgtgactgc tgactttgtc aaaccaggtg cggttgtcat tgacgttggg
     5521 atgaatcgag atgaaaatgg gaagctctgt ggagatgttg attatgaggc agttgcacca
     5581 cttgctagcc atatcacgcc agtccctgga ggtgtcggtc ctatgaccat taccatgctg
     5641 atggagcaaa cttatcaagc agcacttcgg acattggata gaaaataaga gaaacattcg
     5701 attaatagag tgtattttct atagctatat ctaaaatggc agaaatgaat attaaatttt
     5761 agatataaga ttacaaaagg aggtctgcgt ctccttttta ttgtataata aaagtgagag
     5821 gaaaaaagga tgaaagtgat taatcaaacc ttattagaaa aagttattat tgaacgttct
     5881 cgttcaagtc ataaaggaga ttatggtcgt ctgctgctgc ttggtggtac ttatccttat
     5941 ggaggtgcca tcatcatggc tgctttagca gctgtaaaaa gcggtgcagg attggtgacc
     6001 gttggaacgg acagggaaaa tatcccggct ctgcacagcc atttacctga gcctatggcc
     6061 ttttctcttc aagaccagca attgttaaaa gagcaattgg agaaggcaga agttgtcttg
     6121 ctggggcctg gtttacgaga cgatgcttct ggagaaaatc tagtaaaaca ggtctttgtt
     6181 aatttaagcc aaaatcagat tttgattgta gacggaggtg ccttgaccat tcttgctagg
     6241 acaagtttgt catttccctc aagccagctt atcctaactc ctcaccaaaa agaatgggaa
     6301 aaattatctg gaattacgat tgaaaagcaa aaggaagatg caacggctag tgttctgact
     6361 tccttccctc aaggaacaat tttggtggag aaaggcccag ctactcgtat ttgggaagtt
     6421 ggccaatctg attattacca gttacaggtt ggtggtcctt atcaggcgac tgggggaatg
     6481 ggagatactc tggctgggat gatcgcagga tttgtaggcc aattccgaca ggccagtctc
     6541 tacgagcgtg tggcagtagc gacccatctt cattcagcca tagcccaaga actatctcaa
     6601 gaaaattatg tggtcttacc gacggaaatc agcaggtatc ttcccaaaat aatgaaaatt
     6661 atttgtcaac aagagagggt aagcaaaaat aaacttgttt aaaatagaca gataaatcta
     6721 cttccttctc ttaatttatg attcttgaaa tacgcctgct ttaaggctaa actagacgta
     6781 tcaaagttaa gagtttgttt ttgtaactgg aaagagatga acaaatcaaa tacataaaag
     6841 ataaactcat ttttattcgt ttggtaaaaa taaaatgcat atttttaaag aaagattgat
     6901 gaaaaatgta gatttgatgt ttttacttga ataaaaagcg gtttcatagt aaaataagaa
     6961 ctgagaatga tggaggtaaa tcggtggaaa atctgaagaa aatggcaggt atcaaggctg
     7021 ctgagttcgt gagcgatgga atggtcgttg gacttggaac aggctcgact gcctattatt
     7081 ttgtcgaaga aatcggtcgt cgtatcaagg aagaaggatt gcagattaca gctgtaacaa
     7141 cttctagtgt gaccactaaa caggcagaag gccttaatat cccgctcaag tctattgacc
     7201 aagtagactt tgtcgatgtg acgattgatg gcgcggatga agtggatagt cagtttaatg
     7261 gaatcaaagg cggtggtggt gcccttctca tggaaaaggt ggtcgcaaca ccatcaaaag
     7321 aatacatttg ggtggtggat gaaagcaagc tggtcgaaaa actaggtgct tttaaattgc
     7381 cagtagaagt ggttcagtat ggtgcagagc aggtctttcg tcattttgaa cgagctggct
     7441 acaaaccaag tttccgtgaa aaagacggcc aacgttttgt gacggatatg cagaatttta
     7501 tcattgacct cgccttggat gtcattgaaa atccaattgc ttttggacaa gaattggacc
     7561 atgtcgttgg tgttgtggag catggtttat tcaaccaaat ggtggataag gtaatcgttg
     7621 ctggacgaga tggagttcag atttcaactt caaaaaaagg aaaatagaag ggggcataag
     7681 atgtctaaat ttaatcgtat tcatttggtg gtactggatt ctgtaggaat cggtgcagca
     7741 ccagatgcta ataactttgt caatgcaggg gttccagatg gagcttctga cacactggga
     7801 cacatttcaa aaacagttgg tttgagtgtc ccaaacatgg ctaaaatagg tcttggaaat
     7861 attcctcgtg aaactcctct taagactgta gcagctgaaa tcaatccaac tggatatgca
     7921 acaaaattag aggaagtatc tcttggtaag gatactatga ctggacactg ggaaatcatg
     7981 ggactcaaca ttactgagcc tttcgatact ttctggaacg gattcccaga agaaatcctg
     8041 acaaaaatcg aagaattctc aggacgcaag gttattcgtg aagccaacaa accttattca
     8101 ggaacggctg ttatcgatga ttttggacca cgtcagatgg aaactggaga gttgattatc
     8161 tatacttcag ctgaccctgt tttgcagatt gctgcccacg aagacattat tcctttggat
     8221 gaattgtacc gtatctgtga atacgctcgt tcgattaccc ttgagcgtcc tgcccttctt
     8281 ggtcgcatca ttgctcgccc ttatgtaggt gaaccaggta acttcactcg tacggcaaac
     8341 cgtcgtgact tggctgtatc tccattttcc ccaactgttt tggataaatt gaatgaggct
     8401 ggtatcgata cttatgctgt gggtaaaatc aacgatatct ttaacggtgc tggtatcaac
     8461 catgacatgg gtcacaacaa gtcaaatagt catggaattg atacactatt gaagactatg
     8521 ggacttgctg agtttgaaaa aggattctca ttcacaaacc tagttgactt tgatgccctt
     8581 tacggccatc gtcgtaatgc tcacggttac cgtgattgct tgcatgagtt tgatgaacgc
     8641 ttacctgaaa ttatcgcagc tatgagagag aatgaccttc tcttgattac tgcggaccat
     8701 ggaaatgacc caacgtatgc aggaacggat cacactcggg aatatattcc attgttggcc
     8761 tatagccctg cctttaaagg aaatggtctc attccagtag gacattttgc ggatatttca
     8821 gcgactgttg ccgataactt tggtgtggaa actgctatga ttggggaaag tttcttagat
     8881 aaattggtat aagatgacgc gctatgcttt gctggtgaga ggtatcaatg ttggtggtaa
     8941 gaataaggtc gtcatggcgg agcttcgtca agaattgaca aacttgggac tggaaaaggt
     9001 tgagagctac atcaacagtg gcaatatttt ctttacttcg atagattcca aagcccaatt
     9061 ggttgaaaag ctagagactt tctttgcagt ccattatcca tttattcaga gcttttcttt
     9121 actgagtcta gaggactttg aggcggaact tgaaaatcta ccagcttggt ggagcagaga
     9181 cttggcacga aaagattttc tcttttacac tgagggtttg gatgtggacc aagtcatcgc
     9241 gacagttgaa agtttagagc tgaaagatga agtgctttat tttggaaaac ttgggatttt
     9301 ctgggggaaa ttttctgaag aatcctattc taagactgcc tatcataagt acttgctgaa
     9361 ggtgcctttc taccgccaca ttactattcg taatgctaaa acctttgaca aaattggtca
     9421 aatgctaaaa aaataataaa ggagacacac aatgacattt ttaaacaaaa tccatgaaac
     9481 tgctactttc ctgaaagaaa agggaattgc agcccctgag ttcggtctaa tccttgggtc
     9541 aggacttgga gaattggcag aagaaatcga aaatccagtt gtagtagact atgctgagat
     9601 tccaaactgg ggccgttcaa cagtagtcgg tcatgctggt aaattggtat atggtgaact
     9661 ggcaggtcgc aaggtcttgg ctcttcaagg gcgtttccat ttctatgaag ggaatcctct
     9721 agaagtggtg actttcccag ttcgtgtgat gaaagttctt ggatgtgaag gtgttattgt
     9781 aaccaatgca gctggcggta tcggatttgg tcctggtacc ttgatggcta tctcagacca
     9841 tatcaacatg acggggcaaa atccattgat gggtgaaaac ttggatgact ttggcccacg
     9901 tttcccagat atgtctaggg cctacacacc agaataccgt gccactgccc atgaagtggc
     9961 taaaaaactt aatatcaagc ttgatgaagg tgtctatatc ggagttactg gtccgactta
    10021 tgaaacacca gcagaaattc gttcctataa gacactggga gcagatgcag ttggtatgtc
    10081 tacggttcct gaagttatcg tggcagccca ctctggcttg aaagttctgg gaatttcatg
    10141 tatcactaac tttgcggctg gtttccaaga agaactcaat cacgaagaag ttgtagaagt
    10201 gactgaacgt gttaaaggtg atttcaaagg cttgcttaaa gcgattcttg ctgaattgta
    10261 agaaaaaaga tttaaaaggg ggagtgcctc tgtcttttca ggattgactg cctatccgta
    10321 ttaaagaaga aacagaggaa tactatgagc ttcttcctgc tcttataact gaaagaagcg
    10381 gaagaatagg tatgtctgat ctgatagcca gcattgtgaa agacaagatt ctaggatact
    10441 agcattagct tcctagccaa ggagactagt atgataagga gagatgagaa tgaattgact
    10501 ttctgaattt ctcagtctta tcatatatag cacaatgaga tttcgcttga gtctgcttgt
    10561 aaataaacga aaagaaagat aagaaataat gaaaattggt caacgaatta tgcgctttgg
    10621 cataaaaaat taagtatcgg agttgtatct gttgtagtcg gctttgattt ctagctccag
    10681 ctggaatttc agccaatgaa gtaaagcaag atgtaacatc tgaagtggta ataggtgtgc
    10741 tagattctaa ggaggaattg aaagagtcag aaaatgatgc tccaaaacta gaaactcctc
    10801 ttagagagga gccaagacta gctcctcaaa cgcttccgga agcaagtgaa gttcttgaaa
    10861 acaaaaggga agagtcaaaa gtagagataa cataaccagc tcaagcggat gatatccgca
    10921 aggttgttgg ggaattagcc aaggatataa gtattactaa gttgtatatg acaggtcatt
    10981 ctcttggagg ctacctagct cagattgcag cggttgaagc ttaccaaaaa tatcctgatt
    11041 tttataacca tgtattgagg aaagtgacaa ctttcagtgc tcctaaagtc attacttcca
    11101 gaactgtttg gaatgctaag aatggtttct gggatgttgg tttggaaagt cgtaaattag
    11161 ctgttagtgg aaaaattaag cattatgtgg ttgataatga caatgttgtg actcccttga
    11221 ttcataataa tcgtgatatt gttacattta caggtaattc acgctttaaa catcgttctc
    11281 gtggctattt tgaaagtcca atgaatgata ttcctaactt taatattggt aaacaagcta
    11341 ccttggataa acatggttat cgtgatccga aattggataa agtgcgattc tttaagaaac
    11401 aggctctgcc tcgatcttct agtcaaccaa gcgctgaacc aatggaaaat attgccttag
    11461 gaaaacaggt tactcaaagt tcgacagctt tcggaggaga tgctagaaga gctgtggatg
    11521 gcaaagtcga tggtaactat ggtcacaatt ctgtcactca tacaaacttc caatctaagc
    11581 cttggtggca agtagatttg gctaaagaag aaaccattcg ccaaatcaat atttacaacc
    11641 gaacagacac tgcccaggat agattggcaa actttgatgt cattctttta gacagttctg
    11701 gtaaagaaat tgagtgaaaa cgtataacat ctcctaaaga tgtgtcagca caaattacga
    11761 ttaactataa aaaagtgcgc tatgttcgga ttgagctaga aggctataat gccctcagtc
    11821 ttgcagaagt tgaagttttc cgctttatag ctacgaatgc tgaaacggcg acacaagttt
    11881 ctaagccagt tcaaccaatc agtcagactc ctgtgaaaga taaaacattg acaattcaac
    11941 acagtggagc ttacattgcc cgctactcca taacttggga agaagtccca gtagataaag
    12001 atggacacca agttgttcgt agtcattctt gggaaggaaa cggttgcaac cagactgcag
    12061 gttttgtcct caacctccca atcaaagaaa atatgagaaa tctgcgagtt aagattgaga
    12121 aaaagacggg cctactatgg aatagatggc aaacaatcta tgaaaacaga ccaattttag
    12181 ctcaacccca ccgtaaaatt acccattggg gtacgacatt gaattccaag gtgagtgacg
    12241 atgatgtctt gtaatctgat ggtacaatga cagttagttt gtctagttta taagaaagta
    12301 ctacctgagc ttgaatagaa ctcaggtagc tctctgtgaa agaacaaaat taatactcaa
    12361 tgaaaatcaa agagcaaact aagaaactag ccgcaggttg ctcaaagcac tgctttgagg
    12421 ttgtagataa gactgacgaa gtcagtcaca tatataatcc aaggcgacgt tgacgtggtt
    12481 tgaagagatt ttcgaagagt ataaacagaa aggtagagcg cgtgttctaa tttgaacacg
    12541 agtagaaaac ttttctaaaa acaaaaacga aaggatgggt aaactgtatt cgctgaactg
    12601 aatacgggcg actctcctct aaatcgaaat taagaaagga attgacccca ccctaaaagt
    12661 agtgggaaaa agatagttga tctagcgagc atcgctcact gcgcccaact cctattttcc
    12721 cttcgctttt tgatgggttt ggtatctttc tcaatataaa atataaaata aagaaaggta
    12781 gagcgtgtgt tttgatttga acacgagcgg aaaactcgga aaatagataa tctgactgaa
    12841 aaatcaggat ttctcgtcag gttcctaatt ttcagtcgtt ttcttctcgc tctttgtatc
    12901 ataaattatg tctatccata ttgctgctca gcagggtgaa attgctgata aaattcttct
    12961 tcctggggat cctcttcgtg ctaagtttat tgcggagaat ttccttgatg atgctgtttg
    13021 ttttaacgaa gtgcgtaaca tgtttggtta cactggtact tacaagggtc actgtgtatc
    13081 tgtcatggga actgggatgg gaatgccatc tatttcgatt tatgcgcgtg agttaatcgt
    13141 agactacggt gtgaagaaat tgattcgtgt gggaactgca ggttctttga atgaagaggt
    13201 tcatgttcgt gaattagttt tggcgcaggc ggctgcaacc aactcaaaca tcgttcgtaa
    13261 tgactggcca cagtacgatt ttccacaaat tgctagcttt gatttgcttg ataaagccta
    13321 ccatatcgcc aaaaaacttg gtatgactac tcacgttggg aacgttttgt catctgatgt
    13381 cttttactca aattactttg aaaagaatat cgagcttggt aaatggggag tcaaggctgt
    13441 ggaaatggaa gcagcagctc tttactatct tgctgcccaa taccatgttg atgcgctagc
    13501 tatcatgacc atctctgata gcttggtcaa tccagacgaa gacacaactg cagaagaacg
    13561 tcaaaatacc ttcactgata tgatgaaggt tggtttggaa accttgattg cagaataatt
    13621 atagccaaaa aggaagccct ttatgaattg taggacttcc ttttcttatc cagaaattga
    13681 tctagctctc tctgatttcg aagaatagtg actttatgtg aatattcttg gcaaagtttt
    13741 tggtaatttt ctttttgagt tttgctacgc ccatcccaaa gaatccatct gataaactcc
    13801 cactcaaagc gttcagggca atctgccgcc atactttctc tgacttttcc acggtattta
    13861 agataacgct taaaggctct aaagagacag gtcaatggcg aaaaattgag aaagatgatt
    13921 tggtcagctt cttgcattcg ttcttggtag tagcaccaag aataattacc atcgatgacc
    13981 caagctttat gcttggtgag aaagtttttt atctcggtta acatccattc gcagtcactg
    14041 tcttgccaac caggttgaaa ttggagtgtg tccatgtgca gttttggaat ggagtagtag
    14101 ttagataact tttctgctag agttgactta ccagaaccag aatatccgat aattgcgatt
    14161 ttcattttct accttttcct atttggagac aaaaaaacag cctctatgga ctgtttctta
    14221 tttagcaagt ttagctgaaa gacgagcttt atcgcggctt gctttgtttt tgtgaatcaa
    14281 acctttagtt tctgctttat cgatagctga gctagcagca cggaaaagtt cttcagatgg
    14341 gtttgcttcg aaagctttta tagcagtacg catagctgat ttttgagctg agttcttttc
    14401 gttttgttta acgttcaatt cagcgcgttt gatagctgat ttaatgtttg ccaatgttct
    14461 tacctccata tttactaact ataccattat atatgaaaac ttacgttttg acaagggaaa
    14521 attacttttt taagtaaatt tcatcgattt catggttctt gcttttatga agaatcactt
    14581 ctgcacgatt tctggttggt tcaatataat tttgcagatt tgtgagattg atactggtcc
    14641 agacctgatg ggcaaaggac tccacttccc caatcggcat ctgagtaaaa cgataatagt
    14701 agctatcagg gtcgttttgg gctaggctca gcattttcaa gaaacggtcc agataccaac
    14761 tttcaatatc atccactcca gcatctacat agatggaaaa gtcaaagaag tcagtgatat
    14821 agagacgatc gttttgtgga ttttgaaaga cattaattcc ctcaacaatt acaaaatcag
    14881 cagctttgac actttgtttc ttttcgggta cgatgtcgta aacttcatga gaatagacag
    14941 gaatatctac atcttgtcca tttttgatgc ggtccaagaa gttgagaaga gcttccatat
    15001 catagctttc aggaaatcct ttacgattta aaatcccctg ctcaatcaag gtttgattgg
    15061 gatagagaaa accatcagtt gtaaccaact caaccgtagc atctgtaaac gtacgggaca
    15121 gtaggatttg aagtaggcga ctggttgtgg attttccaac ggcaacactc ccagaaaccc
    15181 caataataaa aggttgagat ttactttcac gttggaggaa aattcctttt gaaaaggcta
    15241 aatcttcctt agttcgcttg taaatctgaa tcagatgagc caaggggaga tagatatctg
    15301 taacgtcttg gagactgatt tggtcattaa aactcttgat agattccaat tcttcttctg
    15361 tcaaaggagg tgttgtcttt cgatgtaaag attgccaagt ctggcggctg attttttcaa
    15421 aatgtaaaaa ttcgttggtc atttgttttc ccctagatat tttgtctatc ataccataaa
    15481 aagctaaaaa aataaagcgg tttcttgaat gtggtaagtc aatggtatat agtataagtg
    15541 atcaatttat tgatgaaata ggagatagat tctactgatt tataagctta taaaggaggc
    15601 tttttagttc acaacttata ggaggtgtac tatgaaaatc ttaaaacgtt acatattgga
    15661 actctgtttt attttaagtt ttgctttacc ttttataaaa ggaaccaatg cagataatgg
    15721 tagatgcttt gtggaaacct attacggttt tacttttttg atggaacatg ctattgtaac
    15781 agctgtcttt atctgttcgt tcttaattgc tttcttacta aaaaacgatg ggcgaaatgg
    15841 attgctgctg gtagttattg ctttttagtc ctatggattg cgacagaggg ttatttcttc
    15901 catatgtcac cagaagattt gatacgactt tggacaagtt tggaaatcct gacacaaacg
    15961 tatcagttgg gcttttatct aaacattttg ttaggaattt tgttgatgat taagcatttg
    16021 aaggttaagc aatagaaata ataatctgcc tgattataga tgataaactt tttgttttta
    16081 tctggactgt gatatttata gttctaaatg gtttattatt tataagtgtt gaaagagatt
    16141 gaagaaaatg gcttcgtgac tcgctttctt cggtcttttt cgttttatta tcaatttgta
    16201 aacgatttac aatttgagtc aaattatggt aaaatagtgt catgagtaaa atgtattatg
    16261 cagaaaatcc tgacgctgct cacgacattc atgagttgag agtggacttg ttgggagaaa
    16321 aaatgacttt tttgacggat gcgggtgttt ttagcaagaa aatagttgac tttggaagtc
    16381 aactattgct caagtgtctt gaggtcaacc aaggagaaac tgtccttgat gtaggctgtg
    16441 gttacggacc tttgggtttg tccttagcta aggcttatgg agttcaggct actatggttg
    16501 atatcaacac tcgtgccttg gatttagctc ggagaaatgc tgaaaaaaat aatgcaaaag
    16561 cgacgatttt ccagtccaac atctatgaac aagttgaagg acattttgat catgtcattt
    16621 ccaatcctcc aatccgtgcg ggcaagcaag tcgttcatga aatcattgag aaaagtaaag
    16681 atttcttgga aactggtggg gatttgacaa tcgtcatcca gaaaaaacaa ggggctccaa
    16741 gtgctaagtc caagatggag gatgtgtttg gtaattgtga aatccttaaa aaagacaagg
    16801 gatactatat ccttagaagt gtgaaagaat gagagcagtt gatttaatcc aaaaaaaacg
    16861 agacggtcaa gaactgactt caagtgaaat tgaatggctg gtagaaggct atgtgtcagg
    16921 aactgttcct gattatcaga tgtctgcctt tgctatggct gtttatttta aaggaatgac
    16981 gactcgagaa atttctgatt taacgatgaa tatggttaag actgggcaag agtttgacct
    17041 gtcagccatt gatggtgtga aagttgacaa gcattctact ggtggtgtcg gcgataaggt
    17101 aaccttgatt ttagttcctc ttgttgctag cttcggtgtg cctgtagcaa aaatgagtgg
    17161 tcgtggtctt ggccatacag gcggaacaat tgataaattg gagtccatta agggctatca
    17221 agtagaacgt agtcaagaag attttattcg tcaggttcag gatattggag tatctgtcat
    17281 tgggcaatca gaccagctgg tcaaagcaga taagcttctc tatgcccttc gtgatgtgac
    17341 cgcaactgtc gacacgattc ctttgattgc gagttcggtg atgagcaaga aaattgcggc
    17401 aggggcggat gctattttgc tagacgtgac tgtcggtgag ggtgccttca tgaagacggt
    17461 tgatgaggcg cgtgagttgg ctcaaactat ggtagatctt ggtaaggttg ttggacggaa
    17521 gacagtagca gtgattacgg atatgagcca gcctttggga cgagcgattg gaaatcgtct
    17581 ggaaatcctt gaagcattgg agattttgca aggtcaagga cgtcaggata ttacccactt
    17641 tatttgtgaa ttggctcaaa ttatgcttgg tttggcaaat gttaacaaaa ctgttgaaga
    17701 agttcgccaa catcttgaga atggtcaagc actggctaag tttgaggaaa tggtgcaagc
    17761 ccaaggtgga gacttggaag acctctatcg tcctgtaaat gtagctcatg tggtggaaat
    17821 ccctgctcag gaaacgggtg tcatttcagc tcttccagct atggactttg gtctttatgc
    17881 catgaggctg ggtgctggtc gtgcagttaa gtctgatgcc ttggactatg aaacaggaat
    17941 tgtttttgaa aagaagattg gagactccgt tcaaaagggt gaaattgttg caaaagtata
    18001 cacaaatgaa aaaattccac ctcaactagt tacagatttc caaaaatgtg ttaaaataag
    18061 tgatgaagtg aaaaaaatcc gtgaaattgt agaaatcatc tcctaaatgg agggaaaacc
    18121 gaaatgaaat taaataaata tatagatcat acgcttttaa aacaagatgc aaagaaaaaa
    18181 caaattgata gtttgttgtc tgaggctaga gagtatggct ttgccagtgt ttgcgttaat
    18241 ccaacctggg ttgaacatgc taaaaaaggg cttgaaggca cagatgttaa ggtttgcacg
    18301 gtagtaggtt tccctttggg agcaacaact tcagccgtga aagcatttga gacaaaagaa
    18361 gctatccaaa atggtgcaga tgagattgat atggtgatca atgttggagc tctcaaatca
    18421 ggtaatttag ccttggttga gtcagatatt cgcgcagtag tggaagcaag tggtgataag
    18481 ttagtgaaag tcattattga agcttgcctt ctgacagacc aagaaaaagt tgttgtttgc
    18541 caattggccc aaaaagctgg ggctgacttt gtcaaaacat ctactggctt ttcaactggt
    18601 ggtgctacga tagcagatgt tagattaatg cgtgaaacag ttggatctga tatgggagtc
    18661 aaggctgctg gtggagctcg ttcttatgca gatgctcttg cctttgtcga agcaggtgcg
    18721 acccgtatcg gaacgtcagc tggggtagct attttaaaag gagaattggc agatggcgac
    18781 tactgagttg attgaactgg caattgaaac cagcaaacat gcctatgtcc cctattctca
    18841 ctttcctatc ggagcagttt tagtagccaa agacggaaat gtttacacgg gagtgaatat
    18901 cgaaaatgtt agctatcctt tgaccaattg cggtgagaga acagctattt ttaaggctat
    18961 atctgaaggc caaagagaat tttcagaatt gattgtctat ggtcaaactg aaaaaccgat
    19021 ttcaccatgt ggtgcttgtc gccaagtaat ggtcgaattt tttgaacaag atttaaaagt
    19081 gaccttagtc gcaaaagata aatcgacggt cgagatgacg gtcggggagt tacttccata
    19141 ttcttttaca gacttaaatt agtctgagtc gctctttgag tggcaagggt ctttgtgacc
    19201 aatcaatcca tacttgcaac atcgttgcac atcttattta ggaggttcag taatgaacaa
    19261 gaaacaatgg ctaggtcttg gcctagttgc agtggcagca gttggacttg ctgcatgtgg
    19321 taaccgctct tctcgtaacg cagcttcatc ttctgatgtg aagacaaaag cagcaatcgt
    19381 cactgatact ggtggtgttg atgacaaatc attcaaccaa tcagcttggg aaggtttgca
    19441 ggcttggggt aaagaacaca atctttcaaa agataacggt ttcacttact tccaatcaac
    19501 aagtgaagct gactacgcta acaacttgca acaagcggct ggaagttaca acctaatctt
    19561 tggtgttggt tttgcccttc acaatgcagt tgaagaagca gctaaagaac acactgactt
    19621 gaactatgtc ttgattgatg atgtgattaa agaccaaaag aatgttgcga gcgtaacttt
    19681 cgctgataat gagtcaggtt accttgcagg tgtggctgca gcaaaaacaa ctaagacaaa
    19741 acaagttggt tttgtaggtg gtatcgaatc tgaagttatc tctcgttttg aagcaggatt
    19801 caaggctggt gttgcgtcag tagacccatc tatcaaagtc caagttgact acgctggttc
    19861 atttggtgat gcggctaaag gtaaaacaat tgcagccgca caatacgcag ccggtgcaga
    19921 tattgtttac caagtagctg gtggtacagg tgcaggtgtc tttgcagagg caaaatctct
    19981 caacgaaagc cgtcctgaaa atgaaaaagt ttgggttatc ggtgttgacc gtgaccaaga
    20041 agcagaaggt aaatacactt ctaaagatgg caaagaatca aactttgttc ttgtatctac
    20101 tttgaaacaa gttggtacaa ctgtaaaaga tattgctaac aaggcagaaa aaggagaatt
    20161 ccctggcggt caagtgatcg tttactcatt gaaggataaa ggggttgact tggcagtaac
    20221 aaacctttca gaagaaggta aaaaagctgt cgaagatgca aaagctaaaa tccttgatgg
    20281 aagcgtaaaa gttcctgaaa aataatggat ggaagtcatt tcttaggaag cggccaaggg
    20341 ccgctttttt aagagttgag acaaagtcat tttgtctcag taaagcttgc tactagacaa
    20401 actagcaagt tttattgaaa taaaataaga ctctgaaagg aagagcacat ggcacacgaa
    20461 aatgtcattg agatgcgtga tattaccaag gtgtttggtg gatttgttgc caacgacaaa
    20521 atcaacttgc acctacgaaa aggtgaaatt catgcacttt taggagaaaa tggggctggt
    20581 aagtccacgc taatgaacat gttagcaggc cttcttgaac caactagtgg tgaaattgcg
    20641 gtcaacggtc aagttgtcaa tctcgactcc ccatctaaag cagctagctt gggaatcggg
    20701 atggttcacc agcactttat gttggttgaa gccttcacag tggctgaaaa catcatttta
    20761 ggtagtgaat tgactaaaaa tggtgtgcta gatatcgctg gagctagcaa agaaatcaag
    20821 gctctttctg aacgttatgg cttagctgtt gacccttctg ccaaggtagc agatatctca
    20881 gttggagccc aacaacgtgt agaaatttta aaaacacttt atcggggggc tgatatcctt
    20941 atctttgacg aaccaacggc tgttttgact ccatcagaaa ttgatgagtt gatggctatt
    21001 atgaaaaatc ttgtcaaaga aggaaaatca attatcttga ttacccacaa attggatgaa
    21061 attcgagcag tttctgaccg tgttacagtt atccgtcgtg ggaaatcaat tgaaaccgtt
    21121 gaaattgcag gggctaccaa tgctgatttg gcggaaatga tggtaggacg ttctgtttcc
    21181 tttaaaacag agaagcaagc ctctaaacca aaagaagtgg ttttgtctat caaagatttg
    21241 gtggtcaatg aaaaccgtgg tgttccagct gttaaaaatc tgtccttgga tgttcgtgct
    21301 ggagagattg ttggtattgc ggggattgat ggaaatggtc agtctgaact gattcaagcc
    21361 attacaggtc ttcgtaaggt tgaatctggt agcattgagc taaaaggaga ttcaattgta
    21421 ggcttgcacc cacgtcagat tacagaacta agtgttgggc acgttccaga agaccgtcac
    21481 cgtgatggct tgattttgga aatgatgata tctgaaaata ttgcccttca aacctactat
    21541 aaagaaccac atagtaaaaa tggaattttg aattattcaa atattacttc ttatgctaaa
    21601 aagctgatgg aagagtttga tgttcgcgct gccagtgaat tagttcctgc agctgcactc
    21661 tcaggaggaa atcaacaaaa agcaattatt gctcgtgaaa ttgatcgaga tcctgatctc
    21721 cttatcgtta gtcagccaac tcgtgggttg gatgtcggtg ccattgagta tatccacaaa
    21781 cgcttgattg aagagcgtga taatggcaag gctgtccttg ttgtcagctt tgaattggat
    21841 gagattttaa acgtctcaga ccgtattgcc gttatccacg atggtaagat tcaaggtatt
    21901 gtatcaccag aaacaaccaa taaacaagaa cttggtgtct tgatggctgg tggaaacttg
    21961 ggaaaggaga agagtgatgt ctaaaaaatt acaacaaatt tcggttccct tgatttctgt
    22021 attcctagga attttactcg gagccattgt catgtggatc ttcggttatg atgctatttg
    22081 gggctacgaa gaattgttct atacagcctt tggcagtctg cgtgggattg gagaaatctt
    22141 ccgtgctatg ggtcctctgg tcttgattgg tcttggtttt gccgttgcca gtcgagctgg
    22201 tttctttaac gtcggacttc ctggtcaggc tttggcaggt tggattctca gtggttggtt
    22261 tgccctgtcg catccagata tgccccgtcc cttgatgatt ctagcaacca tcgtgattgc
    22321 cttgattgct ggtgggattg tcggagcgat tccaggtatt cttagggcct atctagggac
    22381 gtcagaggtt attgtaacca tcatgatgaa ctacattgtc ttgtatgtag ggaatgcctt
    22441 tatccatgct ttccctaaag acttcatgca aagtacagat tcgaccattc gtgttggggc
    22501 taatgcaacc tatcagacac cttggttggc tgagttgact ggtaactcac ggatgaatat
    22561 tggtattttc tttgccatca ttgccgttgc agttatttgg ttcatgctca agaaaacaac
    22621 tcttggtttt gaaatccgtg cagttggtct taatccacat gcttcagaat atgctggtat
    22681 ttctgccaag cggactatta tcctatctat gattatttca ggtgccttgg caggtcttgg
    22741 tggagctgtt gaaggtttgg gaaccttcca gaacgtctat gttcaaggtt cgtcattagc
    22801 tatcggattt aacggaatgg cggttagttt gcttgcggcc aactcaccaa ttggtatact
    22861 ctttgcagcc ttcctatttg gcgttctcca agttggggct cctggtatga atgcggcgca
    22921 ggtaccatct gagcttgtca gcattgtaac agcgtctatt atcttctttg tcagtgttca
    22981 ttaccttatc gaacgctttg tcaaaccgaa aaaacaagtt aaaggaggta agtaaagatg
    23041 tctattataa ccttgctccc cctcttggtg tcttctatgc tgatttactc agcacctctc
    23101 atctttacaa gtatcggtgg tgttttctct gaacgtggtg gtgtggtaaa cgttggcctt
    23161 gaaggaatta tggttatggg tgccttttct ggagttgtct ttaaccttga atttgcagaa
    23221 caatttggag cagcaactcc atggctatcc ttgcttgtag caggattggt tggtagtgtt
    23281 ttctctatca tccacgcagc agcgacggtt catttccgtg cagaccatgt tgtcagcggt
    23341 acggtattga acttgatggc gcctgccttg gctgttttct tagttaaagt tctttataac
    23401 aaaggacaaa ccgacaacct aagtcaaact tttggacgct ttgatttccc agtcttggca
    23461 aatatcccag tgattggtga tatcttcttc aagtcaacta gtctacttgg ttatctggcg
    23521 attgccttct cattccttgc ttggtttatt ctctttaaga ctcaatttgg tcttcgtctc
    23581 cgctctgtcg gtgaacatcc tcaagcagcg gataccttgg gaatcaacgt ctacaagatg
    23641 agatatttag gggttattat ttcaggtttt ctaggtggaa ttggcggagc gatttatgcg
    23701 caatcaatct cagttaactt ctcagtgaca actattgttg gacctggatt tatcgccctt
    23761 gctgcgatga tctttgggaa atggaatcca atcggtgcta tgctttctag tctcttcttt
    23821 ggactttcac aaagtttggc tgttatcggt tctcaattgc cgttcctaca aggagtgcca
    23881 gcggtttatc ttcaaattgc accttatgtt ttgacaattc ttgtcttagc agccttcttt
    23941 ggaaaagcag tcgcaccaaa agcagatggt atcaactaca tcaaatcaaa ataagcatac
    24001 aaaaaaacgt cagtccaatg actgaactac accccaaaag ttagacagaa aaaatctaac
    24061 ttttggggtg tttttattat gaaattaagt tatgatgata aagttcagat ctatgaactt
    24121 agaaaacaag gatatagctt agagaagctt tcaaataaat ttgggataaa caattctaat
    24181 cttaggta
//
LOCUS       DAVHBD010000035        23749 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000035 DAVHBD010000000
VERSION     DAVHBD010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.035"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(107..1729)
                     /gene="groL"
                     /locus_tag="VVK04_001483"
     CDS             complement(107..1729)
                     /gene="groL"
                     /locus_tag="VVK04_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU3990125.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1745..2029)
                     /gene="groES"
                     /locus_tag="VVK04_001484"
     CDS             complement(1745..2029)
                     /gene="groES"
                     /locus_tag="VVK04_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU3990126.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2299..2694)
                     /locus_tag="VVK04_001485"
     CDS             complement(2299..2694)
                     /locus_tag="VVK04_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU3990127.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2772..3533)
                     /locus_tag="VVK04_001486"
     CDS             complement(2772..3533)
                     /locus_tag="VVK04_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU3990128.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(3566..4192)
                     /locus_tag="VVK04_001487"
     CDS             complement(3566..4192)
                     /locus_tag="VVK04_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU3990129.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4208..4525)
                     /locus_tag="VVK04_001488"
     CDS             complement(4208..4525)
                     /locus_tag="VVK04_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU3990130.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4522..4821)
                     /locus_tag="VVK04_001489"
     CDS             complement(4522..4821)
                     /locus_tag="VVK04_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU3990131.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5106..5297)
                     /locus_tag="VVK04_001490"
     CDS             complement(5106..5297)
                     /locus_tag="VVK04_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU3990132.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5458..6132)
                     /locus_tag="VVK04_001491"
     CDS             complement(5458..6132)
                     /locus_tag="VVK04_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990133.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6138..6584)
                     /locus_tag="VVK04_001492"
     CDS             complement(6138..6584)
                     /locus_tag="VVK04_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3990134.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6698..7201)
                     /locus_tag="VVK04_001493"
     CDS             complement(6698..7201)
                     /locus_tag="VVK04_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU3990135.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7198..7560)
                     /locus_tag="VVK04_001494"
     CDS             complement(7198..7560)
                     /locus_tag="VVK04_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU3990136.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7626..9485)
                     /locus_tag="VVK04_001495"
                     /pseudo
     CDS             complement(7626..9485)
                     /locus_tag="VVK04_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9524..9973)
                     /locus_tag="VVK04_001496"
     CDS             complement(9524..9973)
                     /locus_tag="VVK04_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU3990137.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(10097..10813)
                     /locus_tag="VVK04_001497"
     CDS             complement(10097..10813)
                     /locus_tag="VVK04_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU3990138.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11694..13109)
                     /gene="ply"
                     /locus_tag="VVK04_001498"
     CDS             complement(11694..13109)
                     /gene="ply"
                     /locus_tag="VVK04_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU3990139.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13120..13452)
                     /locus_tag="VVK04_001499"
     CDS             complement(13120..13452)
                     /locus_tag="VVK04_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990140.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13523..14131)
                     /locus_tag="VVK04_001500"
     CDS             complement(13523..14131)
                     /locus_tag="VVK04_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990141.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVF
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14144..14602)
                     /locus_tag="VVK04_001501"
     CDS             complement(14144..14602)
                     /locus_tag="VVK04_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU3990142.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14727..15126
                     /locus_tag="VVK04_001502"
                     /pseudo
     CDS             14727..15126
                     /locus_tag="VVK04_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            15612..16472
                     /locus_tag="VVK04_001503"
     CDS             15612..16472
                     /locus_tag="VVK04_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEU3990143.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQESLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLDKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NVMYMPIIKTIEELDFVLSFEGINTVAVELVFQDLENPIISKKVIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     IKENYYVQKL"
     gene            16456..17517
                     /locus_tag="VVK04_001504"
     CDS             16456..17517
                     /locus_tag="VVK04_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU3990144.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNELKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            17534..18538
                     /locus_tag="VVK04_001505"
     CDS             17534..18538
                     /locus_tag="VVK04_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990145.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSETQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIEEKVTMYINPRNIMQF
                     "
     gene            18550..20244
                     /locus_tag="VVK04_001506"
     CDS             18550..20244
                     /locus_tag="VVK04_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU3990146.1"
                     /translation="MRKSLNWKDCLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            20246..20947
                     /locus_tag="VVK04_001507"
     CDS             20246..20947
                     /locus_tag="VVK04_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU3990147.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNRLLIYLNTSGIKILEIQNGIGNLDEERQLNKIKSTKVSCYLSLKLNENFEHLKLME
                     EMHNIAGVIYVEEIR"
     gene            20994..21593
                     /locus_tag="VVK04_001508"
     CDS             20994..21593
                     /locus_tag="VVK04_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEU3990148.1"
                     /translation="MNIIFDLGNVLIEWNKEKILSKICKNDLEYNLFNQFVFQSNLWI
                     DLDNGKISLEFLENQLIDEMGHQYQDQIHELVWNWFNYVDLYDEVYELIKQLKKKNFQ
                     IYVLSNTSSIFHILLDSVLSKVSSVLDGYVISCEVKMMKPQKEIYLSLVNKYQLDIKD
                     CIFLDDLEENVEAARTLGIKAFQIKERKEISNILKDLLN"
     gene            21603..23630
                     /locus_tag="VVK04_001509"
     CDS             21603..23630
                     /locus_tag="VVK04_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU3990149.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQLLSLYPTLKNFAKYD
                     CIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLFYIHLDYRILALNTAE
                     NLESGNSSIVPVKDGKQILTDQLFDGECDDIYLLTVHSPMNKALEILSEKYKQISGKN
                     IKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQEITSFRQTKSINQNI
                     SKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQ
                     EFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRERLAQSRMNLAVLPQV
                     LTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSPLFDGLNVSAQFEFAT
                     ATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILLTSLGGFLPSKYVMQN
                     RMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELIESVKHRYG"
BASE COUNT         7471 a         4587 c         4240 g         7451 t
ORIGIN      
        1 agcttagctt ttcttcaacc cactacagtt gacaaagagc ctataaaaag aagggttagt
       61 cattccctcc ttttgtgttt tttataagtt gttttctata gaaagcttac atcatcccgc
      121 ccatcatact tggatccatt gctggagctg gggctactgg ttctggttta ttggctacga
      181 ctgcttctgt tgtcaaaatc aagctggcta cagatgctgc attttgtagg gctgaacgac
      241 tcactttaac tggatcaatg ataccttgat caatcatgtt aacccactcg ccagttgctg
      301 cgttgaatcc tataccaagc tcagcatttt tcaaacgatc gataacgata gatccttcaa
      361 atcctgcatt gtgagcaatt tgacgaacgg gttcttccaa agcacggaga acaatattac
      421 gtcctgttgc ttcatctcct gtcaattcca aggtagcaac agctggaatc acattggcaa
      481 gagctgttcc accacctgca acaatacctt cttcaacagc tgcacgagta gcgttgaggg
      541 catcttcaat gcggagtttc atttctttca actcagtttc agttgcggct ccgaccttaa
      601 taaccgctac accacctgac aatttggcca agcgttcttg caatttttca cggtcaaatt
      661 cagaagttgt agtttcgatt tgagacttga taaccgcaac acggtgagaa atcgcttcag
      721 gatttcctgc accttctaca ataaccgtgc tatctttgtc cacggtcact ctcgctgctt
      781 gaccaagagc ttcaattgtc gcatctttca actcaagacc aaggtcttct gtgataactg
      841 ttccgcctgt taagatggcg atatcttcaa gcatggcttt gcgacggtca ccaaaaccag
      901 gtgccttgac tgctactacg ttgaaggttc cacgaatctt gttcaaaaca agagttggaa
      961 gagcctcacc atccacatca tccgcaataa tcaagagtgg acgattgctt tggagaatgc
     1021 tttccaaaag tggcaagatt tcttggatat tggaaatttt cttgtctgta atcaaaatgt
     1081 acggattttc aaggtcagcc accatttttt cgctatctgt caccatgtac tgtgaaaggt
     1141 aaccacggtc aaactgcatt ccttctacga cttcaagctc tgtttccata ccacgtgact
     1201 cttcgatggt gatgacaccg tctttgccaa ctttttccat tgcttcagag atgtactcac
     1261 caactttttc agaacgagaa gatacggctg caacttgagc gatagcttct ttattggcaa
     1321 cagggatggc gttgtttttc aaagcttcaa ctgctgcggc aactgctgtt tcaatcccac
     1381 gacgaatacc gattggattt gcacctgctg tgacgttttt gattccttca cggacgattg
     1441 cttgggtcaa aacagttgca gttgtagttc catcacctgc gatatcattg gtttttgaag
     1501 ctacttctga tactaactta gcacccatat tttcaaaatg gtcttctaat tcaatttctt
     1561 tggcaatagt cacaccgtca ttggtaatca atggtgagcc aaatgatttt tcaagaacga
     1621 cattgcgacc ttttggtccc aaagttactt taacagtatc tgcaaggata tcgacaccac
     1681 ggaccatagc tgaacgggca tctgatgaaa atttaatttc ttttgacata cttactttct
     1741 ccttctattc ttcaatgatt gccaagatgt tagcttcgcc tacgatgata tacttttcat
     1801 cgccatcttt gacatcaaga cctgcgtggg cttcaactaa gacacggtct ccagttttaa
     1861 cacttggagc aaccaagtca ccgttcaagg tacgaacacc ttgtccagta gccacaactt
     1921 gggctgtttt ggttttttct tgggctgaac ctgcgagaac aaagcctcca acagtttgtt
     1981 ctttttcttc tacttttaag accacacggt cccctaatgg tttcaacatc tgatttcctc
     2041 cataatgaga tagatattat tagcactctt tatacctgag tgctaattca tagttctatt
     2101 gtatcactta gtcagaaata atcaagaaaa aagtctgact ttctcaagat aaaaagcctg
     2161 agaccaactc agacttttta atgtttatac tcaatgaaaa tcaaagagca aactaggaag
     2221 ctagccgcag gctgctcaaa gcattgcttt gatgttgtgg ataaagctaa cgtggtttga
     2281 agagattttc gaagagtatt aaaatggcaa ttcttcctct tccaagacta aatctgccaa
     2341 atcttggcct gcattatttt cacgcatggc acgttgagca cgactttcca agagttggaa
     2401 tcctgttaca agtacttcgg tcacgtagtt catttggcca tttttctcaa agcgacgggt
     2461 acgcaattct ccatcaacgg aaatgagact acctttggtt gcgtagcttg ccaaagtttc
     2521 tgctagtctg ccccatagga ccatattgac aaaatcagct tcacgttcac cgttttggtc
     2581 tttgtaacga cggttcacag cgatagttgc tcgcgctacc gacttgtcat tgttggtttt
     2641 gtgcaattct ggtgtagacg ttaaacgccc aatcatgata actttattat acatattttc
     2701 ttcctcctac ttatctattc gtaggaaatc aaaaaaagtt acagaaattt gtaacttttc
     2761 gaggaaattt cttatttttt atgaatcatg aaacctgtcg cctgttgatt ggccataatg
     2821 gtcatatctg taatctgaac acggcgaggc tgactggtca catagactac tgtgtctgca
     2881 atatcctgag cttgcaaggc ttctattcct tggtaaacgg acgcagctcg ctctttatca
     2941 ccatgaaaac gaacagttga gaaatctgtt tcgacaatcc caggctgaat ggttgtcacc
     3001 ttgatatccg ttgcgatggt atcaattcgc agtccatccg aaaaggtctt aaccgcagcc
     3061 ttggtagctg agtaaacagc ggcaccagca taggcgtaga ttcctgcggt tgaccccata
     3121 ttgataatat gaccttgatt gacttttatc attgctggca agaaacagcg agtaaccgcc
     3181 atcagacctt taacattggt atccaacatg gtcaacatat ccaactcctc atagtcttga
     3241 tagggagcca agtcaagagc cagtccggcg ttgttgacca agatatcaat cctccctatc
     3301 gtttctagaa tatcagagca aacagtcttc accatgacca tatccgtcac atctagtgga
     3361 aaagtccaga cggtttgatt tggaaagctt actgcaaact ccgacttgag gatttctaat
     3421 ctgtctatcc gtcgtcctgt tagaacgaca tcctcaccct gctccagata agcacgcgca
     3481 atcgcttcac cgattcctga ggttgctccc gtaatcacta cattttttgc catcttattt
     3541 ccttctatca gatgctgaca agttcctagg cagtccagtg tttcgctggg tcgaacggtg
     3601 ttccgacaac ttggtcttct gataattcaa gcaccccacg tttttgcgga gcatttggca
     3661 aatgcaattc acgaggacta cacatcatcc caaaactctt ttcaccacga agttcgcctg
     3721 ggaaaatgaa attccctttt ggcatcatgg caccaggaag agccacaatg gttttcaacc
     3781 caacacgcgc attaggtgct cctgcaacga tttgcactat cttgtcactt gcgactgcaa
     3841 cttggcagat gttgaggtgg tcactgtctg gatgagctac catctcgaca atttcaccaa
     3901 caacaaactt aggttcctta tcattaacaa tttcttctgt aaaaccttcc gcctgtaatt
     3961 cttggttcaa acgagcgact tgctcatctg ataaaaagac ttgaccgcgc tctgcaattt
     4021 caaacaagct cgaaacctca aaaatgttcc aagctactgt ttccccattt tctttgagga
     4081 aaacacgggc taccttgcct ttgcgttcca cattcagttt ggcatctccg ctatttttca
     4141 cgatgaccat aaggacatca ccgacatgtt ctttgttata cgtaaaaatc attgtttcct
     4201 ttttctccta tttcaatcct gctaaaaaat cgttaatttg ctccttactt ttacggtcgc
     4261 gattgacaaa acgaccgatt tccttgtcct tttctagaac aacaaggcta ggaattccgt
     4321 aaacatccca gagtttggcc aaatccatat actgatctcg gtccattcga ataaaggtga
     4381 actctggatt ggtctcttca atctctggta aggcaggata aatataacga caatcgccac
     4441 accagtctgc cacaaaaagg aagaccttct tgcccgcttt ttccactaaa gatgctaatt
     4501 cttctaaact tgctggctgt atcataagac ttcctcctca tagactaggt cttcattttc
     4561 atagacaaag gtataatgac ggccatcctc aaaaatgacg ccaccaacca agctctccag
     4621 actgctttcg taaacttgaa cataaagggt cgcaatttcc cccatgtcgg aaaaatggtc
     4681 tcgcacaatc tctgtcaact cttcctgagt cttcatgagc ttacggtcat ctgcaacttt
     4741 tttcgtagca agagcaaggc ttccgatacc tagcagagcc aagcctgcca tccacatttt
     4801 tttagctttc ataccattca ttttaacaca aaaaaggctt caggacaaat gaggaagcag
     4861 cagaaaagca agtaaaaagc ctcttccttt aaggaaaagg acttcttata ctaagagcaa
     4921 actagaaagc tagccgcagg ctgctcaaaa cacggttttg aggttgtaga taaggcgacg
     4981 ctgacgtggt ttgaagagat tttcaaagag tattattctt attgccaggc acctaagttg
     5041 ccaacgtagt aaccatcagg tgtgtaggta ttgcgaagca tcttacctga tgaagccaga
     5101 taatactact tgccattgtc tttgacccaa tcattcgcaa tcatggaacc agaagaactt
     5161 acataatacc attctccctt gtcataaacc caagtactga ctttcatggt tcctgagcaa
     5221 ttaaaggcaa aaaaactgtc caatatcatt cgttttttaa aagcatttga cactacatca
     5281 tctacgctgt agtacataga tacatcaaac gtaaaagcca aaatatcgaa aaatatacaa
     5341 cttttaaagg cagcatttca ttttttaaag tttaacaacc atagaactga aatcagagca
     5401 aggcatcaat ttcctactct tagtacgtct attttgatgg ttgaagtgaa gattttttta
     5461 tttaacgtag acaatttcca acttcccaaa agccacatct ccacggatag tcaaggtttt
     5521 gctggttggg gctacaggag cgtcagcctt agctgcacca aaggaggttt ctactttcaa
     5581 atctacacgc cagtgttgtg gaacatagac ggttgcattt ccgaaggcca cttcaatatt
     5641 taaagttgca aaatcaccta gcatctctgc attatcatag tagattttag catccccaaa
     5701 agcgacttcc acttggtcat ctacgagatc ttgatcttgc ttatagaagg tcccgctacc
     5761 aaaagcgact tccttatccg tgacgactgt ttttttccca ttgtaccacc attttttttc
     5821 attccagaac ttacttgaat gcgtcagata accaacacca agtaccacca agatgctagc
     5881 ccaaataaga gaatgattgg taactggtaa caagtcataa gcgtaatttg caatgatgag
     5941 cgccagtaaa cctgtaaaaa ctgccgaagt gagatgacgt ctaaggatgg actcaatgga
     6001 cttataagca aaaaaaacaa tacctagtaa aggccatatt ttaccatcca aagaaggaat
     6061 tccaaaattc ccttgcagca agatccaagc tgctaaaacc aataaaacaa taccaaatgc
     6121 tttctttttc atgtttttta cctcatgttt cttagatttt cttttaggag ggattggtaa
     6181 tgccgtgaga catgaacctc cttgtgcgtc tgataaaagg aaatggtgcc cgttcctgaa
     6241 aaggacttgt ccactgagta aatctgacgg atgtttgcga tcgttgactt ggaaactcga
     6301 ttaaaatagc gaggcaagat agactccaac tcatagagct tgaggcgaac ctcataagct
     6361 tccttctggt tatgagcgta gatcttgctc ccttctgttt caaagaagag aatttctgac
     6421 aggtctagat aatattcacc tgtccccttg taaaaagtca acctcggagc ctttgactct
     6481 tgcaagagcc gttgcaagtc tgcaatttca tctgtcaaag tgggggtctt gatgacaatt
     6541 tcagtctcct ctaaattgcc gtcaatctca attcgtaact tcatcacatc tcctttctga
     6601 ctctactata tcaaagctaa gttaggaata caagggcaaa aaagcaagtg gtcaatttga
     6661 agcagtaagt ggttgtagga ctagcttaac ttacatgtca gaataggaag aaaaggaatc
     6721 cccacaccaa accacaagca tagccaacca agacatcctt gggataatga acacccccta
     6781 aaaccctcac caaccccagc aaagctgaaa agatcaagca tactaagcca ataggtagac
     6841 tagcatgcag acaggccatg gagatgatag ttgccgaaaa gacatggcga ctgggcatcg
     6901 accgtcccga actatcctta tcaagaaggg gacagatatc ccaagtttca taaggtctcg
     6961 ggtgattgat tttcttacga aacagggaca aggccacaaa acctgatgca ggaataagca
     7021 cataaacccc aacttgctga ccaagtccta gttgcaggta agtggtgact agcaagatca
     7081 gatagaccag gggcatggcg actgtcatca aacgattgaa actgcgtaat aggaataaaa
     7141 gaattggacg actagttagt ctggagctga tatttcgata ccattcttga taatttttca
     7201 tttatgcttc tcatactttt ctagaacttg ttgagatgtt ttccccttgg caagccaatc
     7261 cactagcttg tccaagcgac gtatttcctg catcagagga tcatcaattt cctcaatacg
     7321 gacaccgcaa atcttccctg taattgcaat tcgttcaggg acataatatg gtgcttgtct
     7381 aaaaaaatct ccgtaagtaa catccctatc cagacaagca agaacatcac tcacttcata
     7441 ccctgtcaac caactggtca cttggtgaac tgactctgcc tttccaccct ttcgctcaac
     7501 ttttgcaatc aaggctaagt agacagcagc aaatttcata ttgtataatt tctgactcat
     7561 acttctctct ttctatgtgt actagtataa ataagaaaaa gaaggccgtc aagccttctt
     7621 ttgatttatt cttctgcttc atcttctgta aattgactat tgtacaagtc agcgtagaag
     7681 ccaccttgcg ccatcagttc ctcatagttg ccttgctcga tgatatttcc atctttcatg
     7741 accaagatca agtctgcatt tcggatggtt gacaagcggt gggcaatgac aaaggatgtg
     7801 cgtccttcca tcaaacggtc catggctttt tggatcaatt cctctgtccg tgtgtcaaca
     7861 gaagaagtcg cctcatccaa aatcaaaagc ggtgcatcct taagaagggc acgagcaata
     7921 gtcaatagtt gtttttgtcc tacagacaag gtcacggtgt catccaagat ggtatcatag
     7981 ccatctggca aggtcataat aaagtggtga attcccacag ccttactagc ttccatcatt
     8041 cgttcatcac taatccctat ttgattatag atgagattgt ctcgaatagt tccttcaaag
     8101 agccaggtat cctgcaagac cattgaaaag gcatcgtgca cttctgaacg cgtcatagcc
     8161 ttggtatcca caccatcaat gtgaatactt cccttatcaa tctcatagaa tttcatcaaa
     8221 agattgacaa tggttgtctt accagtccca gtcgacccaa caatggcaac cttttgacca
     8281 gcatgagctg tcgcagagaa gtcatagtct tgaacattga caccgtccac cagaatttct
     8341 cctgctgaca cgtcgtagaa acgtggaatc agattgacca gagttgattt accagaacct
     8401 gttgacccaa taaaggccac tgtttgacaa gtttctgctt taaagctaac atgttcaata
     8461 actgcctccg aatttgccgc atagcggaag gtcacatcct taaactcgac ctgacctttg
     8521 aagttttcat cagtcagctg tacttgaaca gggttttgga tagaagaatg caaatctaaa
     8581 acttgattaa tccgcttagc agagaccata gttcggggaa gaacgatgaa gagtgctccc
     8641 atgagaagga agcccatgac aacctacata gcataagaca tgaaaacaat catgtcacta
     8701 aagagaggca gacgcgctat cggagcagcg tcgttaatca cataggcccc aatccagtaa
     8761 atcgccacac tcaaaccact tgaaatcccc atcatgatag gattcaaaat agccataaga
     8821 cggttgacaa acaaatttta acgggtcaat tcatcattta ctgctgcaaa tttttcattt
     8881 tgataatcct ctgcattgta ggcacgaacg acacgaatac ctgttaaact ctcacgagtg
     8941 atactgttca gtttatctgt cagcccctga atcaaggact gttttggaaa ggctaacgtc
     9001 atcaaaacgg tcgtcatcag gacgttgata atcactgcca caagtacggc ccagagccag
     9061 tattctgaat gacctaaaat cttcccaata gcccagatag ccataattgg accacacgtt
     9121 accacttgca agcccatagt aatcaacatt tgaacttgag taatgtcatt ggtagtacgc
     9181 gccaagaggc taggaattga aaatttctta atctctgtct gcgagtaatc caaaactcgg
     9241 ttaaaaatat cacttctcag cctactagta taagaagccg ccactcggga tgcaaaaaat
     9301 ccaactgcaa ctacggacaa gaaggcaaga aaggacattc ccatcatcat gcttgccggc
     9361 tgccacaact catctaaatt agtttcttga ctacctagca aatccgtaat tttcgagata
     9421 taggtcggca ctttcaactc tagatagacc aaaaagcaag taaagagaat ggctagtaaa
     9481 atcatccccc attcttttct actaattctt ttgactaatt tctttattct ctcctcctat
     9541 tcccttgata ttttgcctgt agttgaccga gaaccttctc aaaaatcagt aattcatctt
     9601 catcaatgtc ttccatcaac tgcttgtcta tgcgttcaaa aaaagcctta acctgttgca
     9661 tctgagaacg tgctttgtcc gtcagacgaa caaacttagc ccgcttatca acaggactcg
     9721 cctccaattc caccaaacca ttttgcacta tacgcttaac cagattacta gcaacagact
     9781 tggtaatatt gagttcctgc tcgatatctt taatcaagac caagtcttgg tttttctcgc
     9841 gattatccaa aaaatgcaca acctgacctt gcggcccacc cataaattca atgccgcaac
     9901 gtttggcttc cttttgcacc atcaggtgaa tttgatgacc aaaacgctta aagactaaca
     9961 tcggtttatc cataatctcc cccttctaaa taaaaatagt tctctggaga ataattaaat
    10021 ttctatgaga actattttct tgattaaaaa aatcccaagt gattttctca cttaggatca
    10081 tgttctatag gttaaattaa aacccatcta cgttcgtata aatcttttgg acgtcttcgt
    10141 cgtcttcaag aacgctgtaa agtttttcaa aggtttcaag gtcttcgcct gacaattcca
    10201 cttctgactg aggaatcatt tccaattcag tcacttggaa ttcttcaata ccagactcac
    10261 ggagagcaac gatagccttg tgaaggtcag ttggcgctgt gtaaactgtg attgtacctt
    10321 cttgtgcttc tacgtcatcc acatccacat ccgcttcgag caattgctca aagactgcgt
    10381 ccgcatcttc acctccaaat acaataacac ctttgttgtc aaaaaggtaa gaaacagaac
    10441 ctgaagcgcc catgtttccg ccgtttttac caaaggctgc acggacattg gctgctgtac
    10501 ggttaacgtt agaagtcaaa gtatccacaa ttagcataga gccatttggc ccaaaacctt
    10561 cgtaacgtcc ttctgtaaag gtttcgtctg tgtttccttt ggctttatca atcgctttat
    10621 cgataatgtg ttttggcact tgggcttgtt tagcacggtc gataacgaat ttcaaagctg
    10681 agtttgattc tggatctgga tcaccttttt tagctgctac atagatttct acaccaaatt
    10741 ttgcatatac tttagagtta gctccatctt tagccgtttt cttggctacg atattggccc
    10801 atttacgtcc cattaggaat ctcctttttt cacattttaa tctttcttat tataacacaa
    10861 gtttttttga ttttcactag aggaaatgga ttttattagc aaatcaagct aggatagcac
    10921 tttacctgct aagatggtct tgcctttcta tctttatcaa cagacactca tccacattca
    10981 aaaaacaaac tagaccatta tctgcaaata gaaagtttca gccaagtttg acaaagtcag
    11041 ctcaaattac tgtttgaagt ttgtagatat aagcgacaaa aacaatcata ctgcaccttt
    11101 tgttgacagt ctactccaga catatcatag ttcaagtaaa tactttgaaa ttcaacagtt
    11161 cttataggcg ctattgtatt ctaagaaatc aatagaagag tttctaagca aacctctaat
    11221 actcaataaa aatcaaagag caaactagaa agctagccgc aggttgctca aaacactgtt
    11281 ttgaggttgc ggatagggct gacatggttt gaagagattt tcgaagagta taatttacgt
    11341 gttcctaaga tggagaagtt agactagtac actggcactt ctaaaccatt gctagcaatt
    11401 gatttgttca tatttaattt cattttttcc ataaatgggt attagatata aacagcaaaa
    11461 tatttccgat acgtgtcatt cttgaatttc caatcatcta aaacaagtaa aggataatca
    11521 atcccctgta tatcaaggaa ttggctaccc tttttacttt tttacacatt ctgtttgata
    11581 gattcatttt aacatcacga gcatactcca atggaaatcg ctaggcaaga gataaacttt
    11641 cagatatccg cagagagatc atcgcctctt tttgtcgcaa gcattctcct ctcctagtca
    11701 ttttctacct tatcttctac ctgaggatag agagttgttc cccaaataga aatcgtccgc
    11761 ttacgcacta gtggcaaatc ggttttttca taaaccgtac gccaccattc ccaggcaagc
    11821 ccggtacact ctctaatttt gacagagaga ttacgaacat tcccttttaa aggaatacta
    11881 gtggtaaagt gagccgttaa atcctgccca tttctgtccc aagccttagg agtcaagact
    11941 tccttacctt gatgatcata ggataattca ttccaagtaa tataatattg ggcaacatag
    12001 gcaccactat gatccagcag taaatctccg tttctgtaag ctgtaacctt agtctcaaca
    12061 tagtctgtac tattttgaaa ggtcgcaact acattgtcac gtaaaaaaga agttgtatag
    12121 gaaatcggca agcctggatg atctgctgta aagcgactgc cttcttgaat caagtcctct
    12181 accatatcca ccttgcctgt tacaactcgg gcacccgaac ttgggtcgcc ccctaaaata
    12241 accgccttca cttctgtatt gtccaaaatc tgcttccact ctgtctgagg agctaccttg
    12301 actcctttta tcaaagcttc aaaagcagcc tctacttcat cactcttact cgtggtttcc
    12361 aacttgagat agacttggcg cccataagca acactcgaaa tatagaccaa aggacgctct
    12421 gcagaaattc ctctctgttt taaatcctct accgttacag tatcttgaaa cacatctcct
    12481 ggatttttaa cagcatctac gctgactgta taataaatct gcttaaaatt aacaatctga
    12541 atctgctttt cgcctgaatg gacagagtta aaatcaatat caagagaatt ccctgtcttt
    12601 tcaaagtcag aaccaaactt gaccttgagt tgttccatgc tgtgagccgt gattttttca
    12661 tactgcattc tagctgggac attattgacc tgaccataat cttgatgcca cttagccaac
    12721 aaatcgttta ccgctccgcg aacacttgaa ttgctggggt cttccacttg gagaaagcta
    12781 tcgctacttg ccaaaccagg caaatcaata ctataagtca tcggagcacg atcgaccgca
    12841 agaagagtgg gattattctc taacaaggtc tcatccacta cgagaagtgc tccaggatag
    12901 aggcgactgt cgttggtagc tgttacagaa atatcacttg tatttgtcga caagctccgc
    12961 ttctttcttt cgataacaac aaactcatcg ggtagctgat taccctcttt gatgaaacga
    13021 ttttcaatac tttctccctg atgggtcaag agtttctttt tatcgtaatt catagctagt
    13081 ataaagtcat ttactgcttt atttgccatc ttctacctcc taataagttc ctggattgag
    13141 ttgcataaac tcagacttgt tcagcgaaat cagccgtggt tggactaagt gatccaaaat
    13201 ttcctcgtac aattcttctg agacattgcg tcgccgtctg gctagataag aagtcggaat
    13261 aaccgtatta tccaacataa ataccttatc taagtcaatc aaggttggtc ttgtaaaagg
    13321 attacgagct agatccggct cttctatcat aaagttcttg accaaacgtc tggtcaagag
    13381 agctggtttg aaggtctgat ttttaaccaa ctctttgttt ttagtcatgc tgttgtcaat
    13441 acagatatac atatgattct tcacagccaa atcgctacta atagtcggaa aaggcaaata
    13501 aagagctaca acatctcctc tcttaatcaa gcaagagcac ccccttttct cctaatgtaa
    13561 catagacagg attgaccaag tcttctgatt gactcagaat ttccaaagtt tgagtttggc
    13621 gcgctgtcaa tttagtagca tcttgtctct tgaatacaaa atgcttgtcg ccaataacct
    13681 tgacaatata atccttctcc aaagctgact ggtaaatcca catcagatgt tgtctgtcct
    13741 gagaactcaa gagagaagga ttttcaagcc tcccgatagt ctgataaaaa tcaaaaacag
    13801 gagctaactc ctgccaatct gattggctag ttgtcaaggc tagaaaaagg gctttgcgag
    13861 ctgatacttc ttggttagcc ttgagagtta ctttcccctc caagtttttt agaaatcggg
    13921 aaactccaga aagcaaattt ttctctaact gcgagaaata aaaacctttc gttcccagac
    13981 ataagtcttt catgtcgctt tctctagcaa ataagagctc aaacatttga tagtaaaaga
    14041 aaaatatctg gcactgggtc gcgctcatct tttccttatc ggcttctttt tttaaccaga
    14101 gcaagggcga caggtagctg gattgagaca tttcctctac ctcctactct tttttaactg
    14161 gagcatctgc actagctgcc acttcttttg actggatact ttcccactgg ttaatctcct
    14221 ctgagataag accttcgcat gtcttgacaa atagggcaaa agccttggtc tttcctgcat
    14281 atttctccgt ttggcattga tagaggaatt tttctttctc caggagttgc gcagtttttt
    14341 ggtaagaaat ccaattttcc tttgcattat acaaattgat aatcccctca cacagcaagc
    14401 cgagactgga taaggcaacc gaaatcaaac ggtagcgatc acctggcata ggaatagcac
    14461 aaaagacagc tatgaggaaa cctgccacga tttctgttat ttttaatacc ttatagcgcc
    14521 tacgatgttg aacgcttttc tttaaaaaat gagctatctg tacgtctaat cgctctgtca
    14581 ggtacatttc ttctggcgtc atattcgtaa ctcctttcat ttactttgat aatcatagta
    14641 taacatattt gaatatcaaa gtatagtaaa aactggacta taacttatta gacttcctac
    14701 gaaacaaaat atggtatagt agttctatga attatgaagc aagtaaacaa ctaactgatg
    14761 cacaatttaa gcgtcttgtt agtgttcagc gtaccacttt tgaagagatg ttagctgtat
    14821 taaaaacagc ttattaaaaa agtcggacaa gctggtaaaa tcttggctga cagtggttat
    14881 caagggccca tgaagatata tcctcaagca caaactccac gtaaattcag caaactcaag
    14941 tcgctaatag ctgaagataa agcctataac catgcgctat ctaaggagag aagcaaggtt
    15001 gagaacatct ttgccaaagt agaaacgttt aaaatgtttt caacaaccta ttgaaatcat
    15061 cgtaaacgct tcggattacg aatgaatttg attgctggta ttatcaatca tgaactagga
    15121 ttctagtttt gcaggaagtc tattttaaaa attgaagaaa ttaaaaagag atgatattag
    15181 ggagaactga tttaaaagtt ctccctattt aacattatta aataaaacct aattatatag
    15241 taaactgaaa taagatataa acaaatgaat tggagcttaa catccatttc cagccaattt
    15301 tttagaaacc acagtgtact actctggatt caacacatta taattgaaat tgaaggttag
    15361 atttaaagta ataaagaata atattacgct ctaaaattag ataaatttca aataattcaa
    15421 ataattaagg atacctatca ctattataaa gtaactgaac aacattttat atttaacaat
    15481 tatttaaaat aataaaatta taacattata taaattattt taaaaaataa tgaaacgttc
    15541 caacttatct attgacacgt tccaagaaat cggatacaat gtaattaaca ataaagatag
    15601 gagaaaataa tttgaatcca ttaaaagaat gctatgaaaa aaacggtata ctaattgcag
    15661 cacaccgtgg tacaaacgga ggaaatatat tacaaaacac atcaaaagcc tatttgaatt
    15721 ccatacgcca taacgcagat atgtttgaag ttgatgtaat tcgttcaaag gatggagaat
    15781 tttttgcatt tcacgatggg caagaatctt tagtatttgg tgaaaaaatt gatattagaa
    15841 ctttgagttc tgaagagatc caaagaaagg aatgttttaa ttcactgaat gaacccatat
    15901 tacaaaagat tgaaaaaatt tctgatgtat taaaaaattt tgagggacag tctttaataa
    15961 atatagatag aagttggttt tactgggata ccttcctaga taagttaaaa acatatccat
    16021 ctttgaatca agttctttta aaatcacctg taaaaaaaga attattggaa atgcttagag
    16081 actctggttt gaatgttatg tatatgccaa ttatcaaaac aattgaagag ttagattttg
    16141 ttctttcatt tgaaggaata aatacagtag ctgtcgaact tgtattccaa gatttagaaa
    16201 atccaatcat aagtaagaaa gtaattgatg atttacatga aaaaggatta cttatttggg
    16261 ttaatgcttt aaccttaagt gattcaatta ttctttcggc taagattgat gatgatacag
    16321 ctattgctca tgatggcgaa tcttggggga aattggtttc aataggattt gatattattc
    16381 aaacagattg gccattatta ctttatcaat atctagttga aaaaaataaa aaaataaaaa
    16441 taaaggagaa ctattatgtt caaaaacttt aaaaagattg cattcacttc ttcactaatt
    16501 ttacttgctg cttgctcaaa caatgcttca aatacaaatc agtctactga tgaaggaagt
    16561 gttgataaat ctcaagaaat tgtaatctat acaaattcgg cttctaatgg acgtgcagat
    16621 tggttacaaa ctaaagcatc agagcaagga tacaatcttc gtttggtaga tatttcaggt
    16681 ggagaactag ctgaccgttt gattgcagaa aagaataatg ctgtggctga tatggtaatt
    16741 ggattaaata aattagaatt taaccgtatt aaagctgaaa aacttcttgt aaaatactca
    16801 ccaaaatggg ctgatgaagt agatagctct ttgggagatt ctgaagggta ttattcacca
    16861 attgtaaatc aaccattagt tttgattggt aataaagatg ctaaaatgcc atccgactgg
    16921 acagatttta ctgattcatc ttataaaggt aaatatggta tttcaaaatt aagtacaggt
    16981 acatctaaga acatctttgc aagtattgtt tcgagatata aagatgaaaa aggtgagtta
    17041 ggaatatctg atgaaggttg gaaagttgca aaagcttacc ttaaaaatgc acacgtttat
    17101 gcagaaggtg aagactatat ctcttcaatt atggataata ataatgagct aaaatatagt
    17161 atgatgtggg gatctggtgt tctacaaaat caaaaagaac gtgaatataa attccaagta
    17221 atgtcaccaa aagttggtgt tccttatgta actgaacaag ttgggatttt aaatacaagt
    17281 aagaagcaag cattattaaa agaatttgta gattggtttg gctcttcaga acttcaaaaa
    17341 gaatggtctg ataaatttgg ttcaattcca gctaataaaa aagctctaga gcaagcaaaa
    17401 gatgaactca aacagtttgc taatagtgtt aaaccacaag aacttgactg ggagtttatc
    17461 gggaaaaaca tcgattcttg gattgaaaaa gcacagcttg aatttgttga acaataatag
    17521 ttaggattaa gtgatgatta catttaagga tattcaaatt aagtataatg attttattgc
    17581 catcgataat ctcaatttaa caatcaatga gggagagttt ttcacatttt taggaccaag
    17641 tggttgtggg aaatcaacaa ctcttcgtgc actagttgga tttttggagc cttcacaggg
    17701 gcaaatacta gttgataatc aagatattac gaatttagat ccagaaaaac gcgaaattgg
    17761 tattgtgttt caaagttatg cattattccc aacaatgact gtttttgata atattgcttt
    17821 tggtctaaaa gttaaaaaag tttctcctga aattattaaa gctaaagttc atgaaattgc
    17881 gaaaaaaatt aatatctcag acgagcaact aaaccgaaat atttctgaat tatcaggggg
    17941 acaacaacag cgtgtagctt tagcacgtgc attagtatta gaaccaaaaa ttctttgttt
    18001 ggatgaaccg ttatcaaacc tagatgccaa actacgagtt tcgttgagaa aagaattgaa
    18061 acgattgcaa aaagaactag gaatcactac tctttatgtc acacatgatc aagaagaagc
    18121 attaacatta tcagatagga ttgctgtgtt taataatgga tttattgagc aagttggcac
    18181 gccgtatgat atttataatc aatccgaaac tcaatttgtc tgtgatttta ttggctcaat
    18241 caataaaatt agccaagaag ttcttaaaaa attacaaggc gagaataaat actttaaaga
    18301 aactgaagga tacatacgct tagagcgtgt taagttagag aaaacttcac ctcaagattt
    18361 atctataaca ggggtaatta gtgatattga gtttaatggt gtacttatta agtataaagt
    18421 agacttgtcg aatagtgaaa gtattcatat tatcgaaaag aatgatggac tatcacgtca
    18481 tataatcgaa gaaaaagtca ctatgtacat taatccgcgt aatataatgc aattttaagg
    18541 agattgtgca tgagaaagag tctaaactgg aaagattgtc tcataagatt aggagtttta
    18601 tggctaatct ttgccctgat tatttatcca aatattgaac ttttgtctgg agtgttttat
    18661 aaaaatggtt catttactct agaggcattc aataagatta tacactctca gagagcgatg
    18721 agtagtatat ttaatagctt tattttggcg atttcaatgg tctttactgt aaatattgtt
    18781 gggacattga ttgttctact cacagagtac tgggatatta ggggttcaaa aatacttaaa
    18841 ttaggttata tgagctctct agtatatgga ggaattgtat tagcgacagg atataaattt
    18901 gtttatggcg ctaatggtct tgtaactaaa acgctctcaa gtataattcc aggtcttgcc
    18961 cctaactggt ttcaaggatt tggtgcagta ttgtttatta tgacatttgc ttgtacctca
    19021 aatcacataa tgtttttaac aaatgcagtt cgtagtgttg attatcatac aattgaagca
    19081 gctaaaaata tgggtgcaag tcctttaaaa gttttcttta gtgtggtttt tccaactttt
    19141 aaacctacgt tatttgcctt aaccatctta acttttttga caggtctttc agcagtttct
    19201 gctcctttga tagtaggggg gaaagatttt caaactatta acccattgat tatcagtttc
    19261 gctaaaacta caagttcgag agatttagca gctttactag ctatcatgtt aggtttagca
    19321 actattctat tattgacact tttgaatcat gtcgaaaaag gaggtaatta tgtatctgtt
    19381 tcgaaaacca aggctagtat taagaagcag ataatttctt ctccattatg gaatactctt
    19441 gctcacattg ttgcgtatgt attgtttgca atctatatgt taccaatagt tttgataatt
    19501 ctatactcgt ttacagactc gttgacgatc aagacgggaa ctttagatct atctaaattt
    19561 acgttagcga actatgctaa tttatttaca gatgctcaat catttcgtcc ttacctagtc
    19621 agcgttgttt atgcaatttt agctgcggta attgctacaa ttatagcaat agtaatttca
    19681 cgtattgtac ataaaaacaa gagtaagttc gataaattct ttgagtatgg tgcactgata
    19741 ccatggatat tgccaggtac attgattgca ctaggattaa tgttcactta taatatacct
    19801 catttaatac tatttaattt agttttagta ggaacagtaa ttattttact tattgcatat
    19861 actattcaaa aattaccatt ttcttataga atgattcggg ctgtattttt cagtatagat
    19921 aatgatatgg aagaagctgc acgtagtatg ggtgcatcta gtttctacac tatggtgcga
    19981 gttattatac cgtatatttt accagtcgta ttatcagtag ttgtattaaa ctttaattct
    20041 ttattatctg actatgactt atctgtattc ttgtaccatc cacttttcca accattggga
    20101 atcgttatta aacagtctac tgatgaaaca gcaactttaa atgcacaggc aatgatgttt
    20161 gtttattctg taattttaat gattatgtct agtgcagctc tttatttatc aagcctattc
    20221 caaggtaaac gaggtaagag ataatatgaa tctttcatac gaactgagta tttgggaaat
    20281 acttcttagg tgctttttag cgattctttt cggtggcatt gttggctatg agcgaggagt
    20341 caaaaaccaa gcagcaggga ttagaaccta cttactagtt tgtttgggaa cttgtgttgt
    20401 aatgatgaca aatcagttca tcactagtcg ttatggtagc ggtgatccta gtcgaatggg
    20461 agcccaagta attagtggct tgggtttcct aggggcagga acaatcatgg taactaatca
    20521 aaaagttaaa ggtttaacaa cagcagctgg attatggtct tcagcaacta ttggtttagc
    20581 tataggcatt ggtttttatg aaggtgctat tttagccgga gttgtactca tagcagtttt
    20641 aactctattt actcctctta aagattattt aaactcgaaa actaaaattg ctgattacta
    20701 cttggttttt agttctttag aaggttataa tcgtttactt atatatttaa atacatcggg
    20761 tattaagatt ttagaaattc aaaatggtat aggaaatctt gatgaagaac gtcaattaaa
    20821 taaaattaag tcaacaaaag tgtcctgcta tttatcatta aaattaaacg aaaactttga
    20881 acatttaaaa ttaatggaag aaatgcataa tattgctggt gttatttatg ttgaagagat
    20941 taggtaaggg tgactttgtc taattttttc tatatttcta atcggagaaa aaaatgaata
    21001 taatttttga tttagggaat gtgttgattg aatggaataa agaaaaaatt ttatcaaaaa
    21061 tctgtaagaa tgatttagaa tataatttat ttaatcagtt tgtatttcaa tctaacttgt
    21121 ggattgattt ggataatggt aaaattagtt tagagttctt agagaatcaa ttaatcgatg
    21181 aaatgggaca tcaatatcag gatcaaattc atgagttagt atggaattgg tttaactatg
    21241 ttgatttata tgatgaagtt tatgaattaa taaaacagct aaagaaaaag aattttcaaa
    21301 tttatgtttt atcaaatacc tcctcaattt ttcatatttt attagattct gttctatcta
    21361 aagtatcatc tgttttagat ggttacgtaa tttcttgtga agttaaaatg atgaaaccac
    21421 aaaaagaaat ttacttgtca ttagttaata aatatcaatt agatataaaa gattgtatat
    21481 ttttagatga tttagaagaa aatgtagaag ctgcaagaac tctaggtatt aaagcatttc
    21541 aaattaaaga gcgtaaagag atctcaaata tactaaaaga tctcttaaac tagaggttaa
    21601 ttatggttac aataaaagat attgcaagag tgtctggagt ctcacatggg acagtttcaa
    21661 acgttttaaa taaaaaaggt aatgtctcag cagctaaaat aaagttagta gaagagactg
    21721 cgaaaaaatt gggttataat atgaattctc aagctcagtt tcttcgaaaa ggcgcttcta
    21781 gtaaatgttt tttcttgtta tttaataatg cacgcaaaaa gtatgctgag tattttgcag
    21841 aaattgatca gttatcttta gatgtagaat atgtttactt acataaattc tcagagatta
    21901 aaaataagat atctgcaatt ttaagtgaaa atcctcaatt tatagtttgc ttaggttttt
    21961 ctccaaaaag attcgttgat attgaagata atattccgat ttttgaagta gatacatatc
    22021 aatctaataa aactttatct tcctttgata gtgataaaat atttgagatt gtacttgagt
    22081 tggttcggac tgaaaagcta tctaatttat attttatttc acttactaat gaaaaagaac
    22141 attctttatt tgaatatttg actcaaaaaa taaaaaactc aactcatata caagtgcaag
    22201 aacgtttaca attgttgtct ctatatccta ctctaaaaaa ctttgcaaag tatgattgta
    22261 tatttgttga tgatgaagat ttgatgcaca cgctattaga cttatttgat tggtttacta
    22321 taattgatag accaaaaata tgtttgatag gttcacgtgt ttggttcgaa aaaagaaatc
    22381 ttttttatat acatttagat tatagaatat tggcactcaa tactgccgaa aatttagaaa
    22441 gtggaaatag ttcaattgta ccagttaaag atggcaaaca aattttaact gatcaattat
    22501 ttgatggaga atgtgatgat atttatttac ttactgtcca ttcaccaatg aataaagcct
    22561 tagaaatttt atcagaaaag tataaacaaa tttctgggaa aaatattaaa attatcgaga
    22621 aaagatatga tgaacttttg gagatgattg agtctggcga tgtttcatcc agttttgata
    22681 tgattagaat ggatatggct tggcttccaa catttgggaa aaagtatttt caagagatta
    22741 caagctttag acaaacaaaa agtattaatc aaaatatttc taagtcggtg tctcgagagt
    22801 atatgtatat tgatcagaag caatatactt ttccattgga tgttagtagt cagattttag
    22861 tatatagaaa agacttattt gaagattcat ttttacaaag acgatacttt gaaaaaacaa
    22921 aaagaaaatt aactgtacca aaaagttatc aagagtttga tgagttaagt gaatttttta
    22981 cattaacaga aaatccattt tcacctacac tttatggcca tagtttagct ttaagttctt
    23041 cagtgagagc agcatgtgaa tttattcctc ggtttcgtga gagattagca caatctagaa
    23101 tgaatcttgc tgtacttcct caggttttaa ctgagtatga gaaaagttat cagtttaccg
    23161 aaaaatcatt taattcttcg tggaacgatt tcgttacgaa cttaaacagt ggtaaaactt
    23221 caatggaaat aattttttca aattatacta gtccattatt tgatggtctc aatgtttctg
    23281 ctcagtttga gtttgcaact gccactatac ctggtaatac tcctgtgata ggtggtggct
    23341 caattggaat ttctaaatat tcaaatagag tggaagaatg tctaaacttt attaattggt
    23401 tatattctga agagatttct attttactaa catctctggg tggtttttta ccatcaaagt
    23461 atgtcatgca aaataggatg ttacaatttc aatatccatg gttatctagt ttagaagata
    23521 catttagtat tgggagtaga acaaaatggt acggctttaa tactgatttt agatttgagc
    23581 agatgttagg gcaagagtta atagaaagtg tgaagcatag atatggataa attaatacta
    23641 aatttttatt actagtttat ttattattgt ttaaaattaa agattcaagt aaacaccaat
    23701 tatatttaaa attattattt tgacattttt ctattgcaaa gttatttta
//
LOCUS       DAVHBD010000036        23245 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000036 DAVHBD010000000
VERSION     DAVHBD010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.036"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            468..1589
                     /gene="mnmA"
                     /locus_tag="VVK04_001510"
     CDS             468..1589
                     /gene="mnmA"
                     /locus_tag="VVK04_001510"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU3990150.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTRDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPRRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1730..2185
                     /locus_tag="VVK04_001511"
     CDS             1730..2185
                     /locus_tag="VVK04_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU3990151.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2195..4108
                     /gene="mnmG"
                     /locus_tag="VVK04_001512"
     CDS             2195..4108
                     /gene="mnmG"
                     /locus_tag="VVK04_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU3990152.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4303..5982)
                     /locus_tag="VVK04_001513"
     CDS             complement(4303..5982)
                     /locus_tag="VVK04_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU3990153.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(5984..6217)
                     /locus_tag="VVK04_001514"
     CDS             complement(5984..6217)
                     /locus_tag="VVK04_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU3990154.1"
                     /translation="MIYKIFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6497..6637
                     /locus_tag="VVK04_001515"
     CDS             6497..6637
                     /locus_tag="VVK04_001515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990155.1"
                     /translation="MYNLFAFAIGVRLLAFSFLLLAFMEEIIYLPNWNDDKPSSCGKL
                     PL"
     gene            complement(7034..7186)
                     /gene="cibB"
                     /locus_tag="VVK04_001516"
     CDS             complement(7034..7186)
                     /gene="cibB"
                     /locus_tag="VVK04_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU3990156.1"
                     /translation="MMKDLNNYCEIPNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7188..7373)
                     /gene="cibA"
                     /locus_tag="VVK04_001517"
     CDS             complement(7188..7373)
                     /gene="cibA"
                     /locus_tag="VVK04_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU3990157.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7550..8233
                     /gene="tsaB"
                     /locus_tag="VVK04_001518"
     CDS             7550..8233
                     /gene="tsaB"
                     /locus_tag="VVK04_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU3990158.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8230..8667
                     /gene="rimI"
                     /locus_tag="VVK04_001519"
     CDS             8230..8667
                     /gene="rimI"
                     /locus_tag="VVK04_001519"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU3990159.1"
                     /translation="MIEIKRIQQRPDLAQAIYAVMIAVYPVNPWTLEQIQADLSQDQT
                     WYVLAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGKGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8657..9667
                     /gene="tsaD"
                     /locus_tag="VVK04_001520"
     CDS             8657..9667
                     /gene="tsaD"
                     /locus_tag="VVK04_001520"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU3990160.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDGELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLISVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEVTDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9707..11013)
                     /locus_tag="VVK04_001521"
                     /pseudo
     CDS             complement(9707..11013)
                     /locus_tag="VVK04_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11405..11485)
                     /locus_tag="VVK04_001522"
     CDS             complement(11405..11485)
                     /locus_tag="VVK04_001522"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990161.1"
                     /translation="MLPLPTYSPEYNPIEKIWAYIKNISE"
     gene            complement(11719..12045)
                     /locus_tag="VVK04_001523"
     CDS             complement(11719..12045)
                     /locus_tag="VVK04_001523"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990162.1"
                     /translation="MEKVDRDKLKIYIETHPDAYLTEIAAEFNCPPTTIHYALKAMGY
                     SLKKSRTYCEQDPEKVNRFLKELNHLSYLTPIYIYETGVETYFYLEYDRALSRQLVSL
                     EEDIII"
     gene            12282..13488
                     /locus_tag="VVK04_001524"
                     /pseudo
     CDS             12282..13488
                     /locus_tag="VVK04_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13481..14277
                     /locus_tag="VVK04_001525"
                     /pseudo
     CDS             13481..14277
                     /locus_tag="VVK04_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14364..15980
                     /locus_tag="VVK04_001526"
     CDS             14364..15980
                     /locus_tag="VVK04_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990163.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16329..16757
                     /locus_tag="VVK04_001527"
     CDS             16329..16757
                     /locus_tag="VVK04_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990164.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            16769..17518
                     /locus_tag="VVK04_001528"
     CDS             16769..17518
                     /locus_tag="VVK04_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU3990165.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVAHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKNYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            17531..18702
                     /locus_tag="VVK04_001529"
                     /pseudo
     CDS             17531..18702
                     /locus_tag="VVK04_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            19098..19961
                     /locus_tag="VVK04_001530"
     CDS             19098..19961
                     /locus_tag="VVK04_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU3990166.1"
                     /translation="MIEKMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYDIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            20247..20480
                     /locus_tag="VVK04_001531"
     CDS             20247..20480
                     /locus_tag="VVK04_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990167.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            20502..21179
                     /locus_tag="VVK04_001532"
     CDS             20502..21179
                     /locus_tag="VVK04_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3990168.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            21191..21856
                     /locus_tag="VVK04_001533"
     CDS             21191..21856
                     /locus_tag="VVK04_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3990169.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            21928..23154
                     /locus_tag="VVK04_001534"
     CDS             21928..23154
                     /locus_tag="VVK04_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU3990170.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7064 a         3944 c         4944 g         7293 t
ORIGIN      
        1 aggtgccctt gcagtcaaca caactgtaga tggctataaa gtcaatgcca atggtgaatg
       61 ggtttaagcc gattaaatta aatcatgtta agaacatttg acattttaat tttgaaacaa
      121 agataaggtt cgattgaata gatttatgtt cgtattcttt aggtacctat cttatgattt
      181 caggaagtgt cattaaaaaa acgactcctt ttctctaact tgaaaaatag attagagaaa
      241 atgggttgtt ttatttatta tagttatgtg aatgaagata agaagaaggt atactcacat
      301 cattcacata atctgtatat tgactataag ttttaaaaaa caatttttaa gctcttcctt
      361 gtcttctcta accaagcgtg ttataatgaa tactgctcaa gcgaccttca atcgtgaagc
      421 acacacgacc ttcaatcgtg aataaacgaa tagatgggag acttaccatg agtgataact
      481 ctaaaacacg tgttgtcgtg gggatgagtg gtggtgttga ttcgtcggtg acggctcttt
      541 tgctcaagga gcagggctac gatgtgatcg gtatcttcat gaagaactgg gatgacacag
      601 atgaaaacgg cgtctgtacg gcgaccgaag attacaagga tgtggttgcg gtggcagacc
      661 agattggcat tccctactac tctgtcaatt ttgaaaaaga gtactgggac cgcgtttttg
      721 agtatttcct agcggaatac cgtgcagggc gcacgccaaa tccggacgtt atgtgcaaca
      781 aggaaatcaa gttcaaggcc tttttggact atgccatgac cttgggggca gactatgtag
      841 cgactgggca ttatgctcga gtggcgcgtg atgaggacgg cactgttcac atgcttcgtg
      901 gcgtggacaa tggcaaggac cagacctatt tcctcagcca actttcgcaa gaacaacttc
      961 aaaaaaccat gttcccacta ggacatttgg aaaagcctga agttcgaaaa ctagcagaag
     1021 aagcaggcct ttcgactgct aagaagaaag actcgacagg gatttgcttt atcggagaaa
     1081 agaactttaa aaacttcctc agcaactacc tgccagctca gcctggtcgc atgatgactg
     1141 tggatggtcg cgatatgggc gagcatgcag gtcttatgta ctatacaatc ggtcagcgtg
     1201 gcggactcgg tatcggtgga caacacggtg gtgacaacgc gccgtggttc gttgtcggaa
     1261 aagacctgag caagaatatt ctctatgtag gccaaggttt ctaccatgat tcgctcatgt
     1321 caactagcct agaggctagc caagtccact ttactcgtga tatgcccgag gagtttacgc
     1381 tagaatgtac ggctaaattc cgttaccgtc agcctgactc taaggtgacc gtccatgtca
     1441 aaggagacaa ggcagaagtt atctttgcgg aaccacgacg cgcgattaca ccaggacagg
     1501 cagttgtctt ttacgatggc gaagagtgtc taggtggcgg tttgattgac aatgcttacc
     1561 gcgatggaca agtttgtcag tacatttaga ttgacaaatt ttctcaattt gctacaataa
     1621 taacagcaat agaaatgatg gtcaaagctc atggatgttg caggcttttt tgtcctgcac
     1681 ttctttgtag ttttgactgt ttttgtgtcg tttaagggaa aggacaagaa tgactcaaca
     1741 agactttcgg acaaaagtag acaatacggt ttttggtgtt cgggctacag ccttgattgt
     1801 ccaaaatcac aagcttctag ttaccaaaga caagggcaag tattacacta ttggaggtgc
     1861 gattcaagtc aatgaaagca cggaagacgc ggtagtccgt gaagtgaagg aagaactggg
     1921 tgtcaaagct caagctgggc agctagcttt tgtggttgaa aatcgttttg aagtggacgg
     1981 cgtttcctat cacaatatcg agtttcatta tctggtggat ttgcttgaag atgccccgtt
     2041 gaccatgcag gaagatgaga aaaggcagcc ctgtgagtgg attgacttgg ataagctcca
     2101 gaatatccag ctagttccag cctttttaaa aacagcccta ccagattggg aaggccaact
     2161 aagacacatt catcttgagg aataggagag aaacatgact tatcatttta ctgaagaata
     2221 cgatattatt gtaattggtg cgggacacgc tggggttgag gcttccttgg ccgctagccg
     2281 tatgggctgt aaggtcctgc ttgcgaccat caatattgaa atgctggctt tcatgccttg
     2341 taatccctct atcggtggtt ctgccaaggg gattgtcgtg cgtgaagtcg atgccctcgg
     2401 tggcgagatg gccaaaacca ttgacaagac ttacatccag atgaagatgc taaacacagg
     2461 gaaggggcca gctgtccgtg cccttcgtgc gcaggctgac aaggaacttt actctaagga
     2521 gatgcgcaag acagttgaaa atcaagaaaa tctgaccctt cgtcagacca tgattgatga
     2581 gattttggtg gaagatggca aggttgtcgg tgtgcgtaca gccacccatc aagaatatgc
     2641 tgctaaggct gttattgtga cgacagggac tgctctccgt ggggaaatta tcatcggaga
     2701 cctcaagtac tcatcaggtc ctaaccacag cttggcttct attaacctag ctgacaatct
     2761 caaggaactg ggcctcgaaa tcggtcgttt caagacagga acccctccac gtgtcaaggc
     2821 ctcttctatc aactacgacg tgacagaaat ccaaccagga gatgaagcac ctaatcactt
     2881 ctcatacact tcacgtgatg aggattatgt caaggaccaa gtgccatgct ggttgaccta
     2941 caccaatggt accagtcatg agattatcca aaacaacctc caccgtgcgc ctatgtttac
     3001 aggtgtggtc aagggagtgg ggcctcgtta ctgtccgtcg attgaagaca agattgtgcg
     3061 ctttgcggac aaggaacgtc accaactctt ccttgagcca gaagggcgca atactgagga
     3121 agtctatgtt caaggacttt caaccagtct gcctgaggat gtccagcgtg acttggttca
     3181 ttccatcaaa ggtttggaaa atgcagagat gatgcggaca ggttatgcta ttgagtatga
     3241 tatggtcttg cctcatcagt tgcgtgcgac tttggaaacc aagaaaatct caggtctctt
     3301 cactgctggt cagacaaatg gaacgtcagg ttacgaagag gcagcaggcc aagggattat
     3361 cgcgggtatc aatgcggctc tgaaaatcca aggcaagcct gaattgattc taaaacgaag
     3421 tgacggttat atcggggtga tgatcgacga cttggtgacc aagggaacca ttgaacctta
     3481 ccgtctcttg accagtcgtg ctgaatatcg tctcattctt cgccatgaca atgctgatat
     3541 gcgcttgact gagatgggac gcgagattgg ccttgtggat gatgaacgct gggctcgttt
     3601 tgaaatcaag aaaaatcaat ttgataatga gatgaaacgc ctagacagta tcaaactcaa
     3661 gccagtcaag gaaaccaatg ccaaggttga ggagatgggc ttcaagccgt tgacagatgc
     3721 ggtgacagcc aaggaattcc ttcgccgtcc agaagtttct taccaagatg tggtggcctt
     3781 catcggacca gctgcagaag acttggatga caagattatc gaattgattg aaacagaaat
     3841 caagtacgaa ggctatattt ccaaagccat ggatcaggtt gccaagatga aacgtatgga
     3901 agaaaaacgc attccagcca atatcgactg ggatgacatc gattctattg cgacggaagc
     3961 tcgtcagaag ttcaaactca tcaatccaga aaccatcggc caagccagcc gtatttcggg
     4021 agtaaaccca gcagatattt ctattttgat ggtgtatctt gaaggtaaaa atcgtagtat
     4081 ttctaaaact cttcaaaaat caaaatgata cgtcgtcggc ttcttacgaa tgagttcaaa
     4141 gcttggcttt gattcatctc cagcctccca tagttccccg aactatggga gctaactcaa
     4201 gttatgcatt ttcctagcct tctggtctga ttttcattga gttttaatct caaaagaaag
     4261 catagagaaa aacagctccg aggacggggc tgttttcttg ctttattctt catctggtgt
     4321 gaggatcatc gggatgatga tcggttcacg ttcggtattt tcatagagga aggggcgaat
     4381 agcgttgaca atggcaccat tgacagattg cacgctggca tccttatttt tcagtgcgat
     4441 acgaatggca ttgaagagga tacgctggct ttggcgaatc aagtcgccag actctctcat
     4501 gtagacaaag cctcggctga ggatgtctgg accagacaga atcatctgcg atttgaagtc
     4561 aacagttgcg actgccagaa cgacaccgtc ttcagataga tcgcgacgat ctttgaggac
     4621 agctgcgcca atttcaccga tacgatttcc atcgacatag atatcttggg cgttgaaatg
     4681 acctgcgata cgagctgagt cagcagtaag ggcaagcaca tcgccattgc tcatgataaa
     4741 gatattgtcc ttctcaacac cagtatccac tgctagtcca gcgtggactt tttgcatgcg
     4801 gtattcaccg tggacaggca tgaagtattt tggcttaatc aagcagagca tgagtttttg
     4861 ctcttgctga ccaccgtgtc cagatgtatg gatattgttc actttaccgt ggataacttc
     4921 gacaccagct tcagaaatga tgttaatcag cttgttgacg ctagtagtgt ttccagggat
     4981 gggactagaa gagaagataa cggtatcacc tggttgtaat tgtacttgac ggtgggttcc
     5041 gttggcgata cgagagaggg ctgccatagg ctcaccctga ctacctgtac agaggataag
     5101 aacttctcct gcaggataat ctttgatttc atttggctcg ataaaggttc ccttaggagc
     5161 tttgatgtag ccaagatcga ttccgttgac aatggccttt tccatagaac gaccaaagac
     5221 cgcaatcttg cgtccagtct taacagcagc ttctgttgcc tgctggagac ggaagatatt
     5281 tgaggcaaag gatgcaaaga tgatacgtcc ttcaatacct tggataatct tcataatgga
     5341 ctgaccaacg actttttcag agttggtaaa ggttggtact tccgcatttg tcgagtcaga
     5401 caggagacag agcacgcctt cttcaccaag ggcagccata cgatgcaagt ccgcaggttc
     5461 tccaactgga gtaaagtcga acttaaagtc acccgtacag acgattttcc cttgaggagt
     5521 atgaatgaca atccccaaag gctctggaat agagtgagtc gttctaaaga aagttgcctt
     5581 gagattttta aaggtcaact cggtgttgtg gttgatttcg taaagtttgg cgttgcgcaa
     5641 gaggccgtgt tcttcgagtt tcccacggat caaagccaag gcaagcggtc cagcataaat
     5701 agggacattt gcttgcttga gtaggaacgg aatcccacca atgtggtcct cgtgtccgtg
     5761 tgtgattaaa acagccttga cgcggtcgat attgtctacg atgtaagagt agtcaggaat
     5821 gacatagtcg ataccaagca agtcatcttc tgggaattta atcccagcat cgacgatgat
     5881 aatctcgtct tggtattcaa ttccgtaagt gtttttcccg atttctccta gaccaccgat
     5941 ggcaaaaacg ccgacttctt caggtttaag agtgtaggcc atattagaac tccgtaattt
     6001 cgaaggcgcc agtttctttt tcgtaatcga gcaatttgtc agacaagagt tcgatatatt
     6061 cgatattgta ctctgggcga ttttcttcga caagttggcg agcagtgata cggccctcaa
     6121 gttctgagct ggcatcgatg tctaggtaaa gcgcgcgtgt tgtttcacgg cgtgggctac
     6181 gttcttttgt ttcttgataa aaaattttgt aaatcatata gttcctttct atttacaggt
     6241 cagcttattc caaactttta gcagatattt gcttgatttc attccatttt gtgtctagat
     6301 tgaccttgat tcgttacaat tatttcaatt ataccacaaa atgaaaaatt agtaaaagac
     6361 ggaaacgaga aagttagggg acgatttctt cggtaagcgt ttgcaaaaat aaagaaaatg
     6421 tgttatgttg ataacggcag tgaaatttat tacttgtcat aattccatat agattttaag
     6481 tcaaggaggt tgccctatgt ataacttatt tgcttttgct atcggagttc gtttgctagc
     6541 tttctcgttt ttgttgcttg cgtttatgga ggaaatcatc tatttgccaa actggaacga
     6601 tgacaaacca agttcttgtg gaaaattacc tttgtgactc tctactcgct ttttctcctc
     6661 ctcatgacct atgtcgtttg gtttgtattt tactttggat taaatgctta gatgccctgc
     6721 ttatgctggg gttttttgtt tgggaatgta gagatagtag atttacgaca cgaaaattcc
     6781 accccatcta tcaagatgag gtggtctttg catttttcta acatgacatg acaatggaat
     6841 tttcaaagct tattattttt atgggagtca ttgttctgct caaaaataga gttgaagcat
     6901 aaaaataaaa caatacaaac agataaatcg aatggtaaag ggatagtagt aatgttcaaa
     6961 tcattgagaa tgctgagcaa actgtaagag atgaagacaa taaaatttat ccttctaaaa
     7021 atgtgtttct tatctagcat gacttaccaa actttttacg aaggtctttt ccaatggtat
     7081 aacctgccat aaataaagcg ataccaacac ctacaccaaa gccacccttt atttcttgca
     7141 attccttatt gggaatttca caatagttgt tcaaatcttt catcatatta atctcctcct
     7201 aaaaaataac cagctgccaa accagaacct ataagtgctg ttccacctgc aatagccttc
     7261 caagatactg ctactccaaa gataaccaag ggagcgagac cgccatcaat atctgacaat
     7321 tcattttcag ataaggataa aaattgattg tcaagaatgt caaaatttgt cattgaactt
     7381 tcctcctttt tcttgttcac ttttatattc ggaaaagaaa aggaaaagtg agcatttttt
     7441 taaattattt ttagttaagt gagggcattt ttgtttgggg ataaagaaaa ttcccatgtg
     7501 ccagcttttg tagtataata gtaagcagac aaaaagatag gaatgtgtta tgaaagtatt
     7561 agcttttgat acgtccagca aggctctttc tctggctatt ttagaggaca agcaggttct
     7621 tgccgagacg acgattaata ttaagaaaaa tcacagtatt acccttatgc ctgccatcga
     7681 ttttttgatg gcaagtttgg attggacacc caaggatttg gaccgaatcg tggtggctga
     7741 agggccaggt agctacacag gtttgcgaat tgcggtagcc actgccaaga ccttggctca
     7801 tactctgaac attgagttag ttggtatgtc tagcctcttg gctctggtgc catatcaaca
     7861 agaaggcttg ttcgttcctt tgatggatgc gcgtcgcaac aatgtttatg caggatttta
     7921 tgaaaatgct aaacctgtca tgccagaagc acatctgcct tttgagcgag tcattgagct
     7981 aatcaagggc gctagtcagg taacctttgt cggagaagtt ggcccctttg ttgagcagat
     8041 tcaaaaacac ttgccaagga ctgattacaa agaaacattg cccaatgcag ctaatctagc
     8101 tcttttggcc tgggacaagg aagcagactc cttgcatgat tttgtgccaa attacctcaa
     8161 acgtgttgag gcagaggaaa actggctcaa gaaccatacc gagtctggtg agtcctacat
     8221 taaacgccta tgatagaaat caaacgaatc caacagcgac ctgacttggc tcaagccatc
     8281 tacgctgtta tgatagctgt ttacccagtc aacccttgga cgctggaaca aatccaagca
     8341 gacctgtccc aagaccagac ttggtatgtt ctggcttatg atggggcaga agtgattggc
     8401 tttctagctg ttcaggagaa tctttttgag gcagaagtcc tgcaaatcgc tgtcaaagga
     8461 gcctatcagg gtaagggcat tgcatcagcc ttgtttgctc aattgccgac agataaggag
     8521 attttcctcg aagtcagaca gtcaaatcaa cgagcgcaag cattttacaa gaaagaaaag
     8581 atggcagtta tagctgagcg aaaggcctac taccatgacc cagtcgagga cgccattatc
     8641 atgaagagag aaatagatga aggatagata tattttagca tttgagacat cctgtgatga
     8701 gaccagtgtc gccgtcttga aaaacgacgg tgagctcttg tccaatgtca ttgctagtca
     8761 aattgagagt cacaaacgtt ttggtggcgt agtgcccgaa gtagccagtc gtcaccatgt
     8821 cgaggtcatt acagcctgta tcgaggaggc attggcagaa gcagggatta ccgaagagga
     8881 cgtgacagct gttgcggtta cctacggacc aggcttggtc ggagccttgc tagttggttt
     8941 gtcagctgcc aaggcctttg cttgggctca cggacttcca ctgatttctg ttaatcacat
     9001 ggctgggcac ctcatggcag ctcagagtgt ggagcctttg gagtttccct tgctagccct
     9061 tttagtcagt ggtgggcaca cagagttggt ctatgtttct gaggctggcg attacaagat
     9121 tgttggggaa acgcgagatg acgcggttgg tgaggcctat gataaggtcg gtcgtgtcat
     9181 gggcttgacc tatcctgcag gtcgtgagat tgacgagctg gctcatcagg ggcaggatat
     9241 ttatgatttc ccccgtgcca tgattaagga agataatctg gagttctcct tctcaggttt
     9301 gaaatctgcc tttatcaatc ttcatcacaa tgccgagcaa aagggagaaa gtctgtctac
     9361 agaggatttg tgtgcttcct tccaagcagc tgtactggat attctcatgg caaaaaccaa
     9421 gaaggctttg gagaaatatc ctgttaaaac cctggttgtg gcaggtggtg tggcagccaa
     9481 taaaggtctc agagaacgcc tagcagccga ggttacagat gtcaaggtca tcattccacc
     9541 tctgcgcctc tgcggagaca atgcaggtat gattgcttat gccagtgtca gcgagtggaa
     9601 caaagaaaac ttcgcaggct gggacctcaa tgccaaacca agtcttgcct ttgataccat
     9661 ggaataaaga gtggctcttt gtcaagtgta gtgggtaggc gaaaagctac aatctggaga
     9721 gtacgaaatt cgtactctct tttttgatgt tcaaagtcat caaaatccgt tttttaaaat
     9781 tgttaaagtt ccggaaacca aaggttttgc gcttgataac cttaatcaaa ttattggtcg
     9841 cttcaagttt agcgttggaa taaggcagct taagtgcgtt gataatctta tctctatccc
     9901 ttaaaaaagt ccaaaagacc gtttgaaaaa gcggatgaac cgttggcagt tcttgcttaa
     9961 tcaatccaaa gaaatggtcg gcattcttct cttgaaaatg aaagagcagg agttgataga
    10021 gttcgtagtg aacctgtaat ccctcagagt aagaaagcag cttatctcgt acttcccgat
    10081 gggttaagtg cattcgaaac gtgggctgat agaatcgttt ctgacagagc ttgaagctat
    10141 cctggtgtag taaatcagtc cagtggactg atttagcccg agcctagaaa cgaaaaagcg
    10201 agggttccaa aagcgcttga gcgcccgata ctccaaggat tttcggtcaa attggttcat
    10261 gatttggatt cgtactcggt tcatagctcg gctcagatgt tagacaatgt ggaagcggtc
    10321 aagaacaatc ttcgcctttg gaaagagttg cttagcgagc cgataataag ggctgtacat
    10381 gtccatggtg atgacctcga ccagctcccg aacctctctc tgatagcgtt ggaaatggtt
    10441 tcgaatcacc gcatgagttc gcccgtctaa aattgcgagg atggatttgg actcaaaatc
    10501 ttgggcaatg aagctcattt tgctcttttt gaagctatac tcatcccaac tcataacttt
    10561 tggcaacttg gtccaatcgg tttcaaactt aaattccctc agttttcgga tgacggtgga
    10621 agttgagacc gccaatctgt gggcaatctc agtcatagac tgcttttcaa ggaggagctg
    10681 agcgattttt tgtctcacca tgttggaaat ctggcaattt ttcttgacaa tggatgtttg
    10741 agaaacgacc accttaaggc aattcttgca ctgaaagcgg cgctttttga gatgcagtac
    10801 cgtgggtaaa ccctgacagt cgagaagcgg aattttagag gctttctgga agtcgtattt
    10861 gatcatcttc ccttgacaat gaggacaagg aggagcgggg gaatccaact ttgcctgaac
    10921 gactagatgg gtttggtatt tcagaacaga caagattttg atatttttgt cttccaatcc
    10981 gagcaaatct gtggtattct taagttgttc catatgaacc ctttctaatg agttggttag
    11041 acgcttttca ttataggtca tatggggctt tttttctaca agaaacgacc ctataattcc
    11101 tggggtggga ttacccacta cagaaattat agagccaaaa cattccaaag tcttgtctga
    11161 ctctggaatg ttttctgttc acagttgttt tgtaactgcc taataagtaa ccgcgctata
    11221 acgaggtatc taccgagatt gtcaattctc cagtatactg ttataaaaaa caaaactgga
    11281 ggattttttt atgtcccccc atcgtcccat cgactgttcc gtagctgccc aataacggag
    11341 tatagtcgtc tgaaacaaga ataggacaaa agtgcctcaa gaaaagcatc gtaatttgac
    11401 aatattattc tgagatgttt ttgatgtaag cccatatttt ctcaatggga ttatactcgg
    11461 gtgaataggt aggaagtggt aacagtctat gccctgctcc ttacacatgt tcattctgtg
    11521 aaaccttgca ttgtccataa tgataaggga tggtgtatct aaagtaggta gtaagaattt
    11581 ttggaagcaa gcttcgaaaa agtcactcgt catcgtatct ttataggtca tcggagccat
    11641 agtatattga aacaaaaagg gcattagtac ttctataaca gtatcgcaat ctctggtgtg
    11701 cgttgtctcg attttaattc aaataattat atcttcttcc agagagacta actgcctgct
    11761 caaggctcga tcatattcga gataaaaata ggtctcaacc cctgtctcat aaatataaat
    11821 aggagtcagg tagcttaagt gattcaattc tttaaggaac cgatttactt tttctgggtc
    11881 ttgttcgcag taggtacggc tcttttttag actatatccc atagccttta gagcgtaatg
    11941 aatagttgtt ggaggacagt tgaattcagc agctatttca gtcaaataag catcgggatg
    12001 agtttcaata tagatcttta atttatctct atcaactttt tcaattaata gtggaagttt
    12061 tcttaaagtt agtgtattga aacgttttta tacagtgcta aaatttgaag tgtagtgcag
    12121 atgtatttgt aatagtatta tagcaattct ttggagaagg tcgagacaag agaaaatagg
    12181 tatctttgag atataagcat gatttactat aaaattattg agttattcat aaaaatttct
    12241 ctatcaaata tcataatgcg tcgtttaagg agatggttac aatgcaatat agttgtggaa
    12301 aaataaatat taatatccct gatggatatg gagacattaa ggatatagtg ttttcggctc
    12361 atattatagt taggtataat aatggacatt gtggaggtat agagatccgc atataattgg
    12421 actttgtaaa aagcagatta gaaggatgtc tctatatcct attttgataa tcgtatctag
    12481 agattcaaag gttattgatg attataaaaa tttagatatt gcctatgttg attgtactca
    12541 atgttcaaat aattttgaaa ctgccttaca cgttaaaaat attttaaaat tattaaaaat
    12601 ccaacttata cactgtcatg gctactcaac taattatttt ttatatatgt taaaaaaact
    12661 tgacaagaat ggatttggaa aggttaagac agtgataaca tgccatggat gggttgaata
    12721 taacttaaaa aagaaattct tgacttattt tgatttttgg acatattcta tgggagatgc
    12781 ttttatttgt gtatctgaaa ctatgaaaaa aagattggag agtataataa aaaataagaa
    12841 gatagttgca ataaataacg gaattaatgt atcaaatagc gatttagatg tagtaggtgt
    12901 tcaagacttt aaaaagaatt ttgtattcca aataacaaaa aaatcatttg ttatgttgga
    12961 aggttggatc cagaaaaaag gccggataga ttccttgaat ttgcagaaaa attattttta
    13021 gtcagagaag atgtgatttt tattatggct ggaaatggta gtatgtgggc tgctttgaaa
    13081 gaaaaaattt gccatttgaa atgtagagat aatttcaggt tacttggtga aatctatcca
    13141 gctactatag tttaccaaat atcggattta ttgtatattt cttctgatac agaaggaata
    13201 cctatgtgtg ttttagagtc aatgtcacaa ggaacttcgg ttttagctag taatgttggc
    13261 gggttaagtg aaattattga acatagggtt gatggatttt tatttgagaa ggaagatgtt
    13321 gagggagtgt gtgcttgtgc taatttttta ctcaatgatt ctgagtattt gaaatatata
    13381 ggtgagaata gtaaatcaaa aataagaaaa catttttctg tgcaaaaaat gtttgtagaa
    13441 accatgagag tatatgatga attattagag aagagtagtc atggatagga atatagatca
    13501 agaattagta agtattataa taccaacaca taataggtat gaatctctga ttagagctgt
    13561 gaaaagttgt ttacatcaaa gttataaaaa tatcgaagtt ataattattg atgataatta
    13621 tagtaatgta aatttaagaa ataaaattat ccatcaattt ggctatacca atcatagaat
    13681 taagttaatt ttaagtaatg aagatttagg tgcaactaat gccagaaaca taggtatcaa
    13741 aaattctaga ggtaagtata tatcattttt agacgatgat gatgaatata tgccagatcg
    13801 aattttaaag ttgatggctt gttttaaaaa gagtagaatg aagaatttag ctttagttta
    13861 tagttatgga ataataattt atccaaatgg tacacgagaa gaggagaaga ccgattttgt
    13921 tggaaatccc ttgtttgttc aaatggttca catcaggacg gtgttgtttt attaaaacta
    13981 cttgctcaag gataccaaat tgatatagtg cgagaattct tggtgaatta ctacgctcac
    14041 agtaaagaaa acggtatcac tggagtgaca caaaaaacaa ttaatgcaga tgaagaatat
    14101 tataattact gtaggaaata ttttaattta ttgagtttca acgagagaat attggttaca
    14161 aagaaatatt attctttaaa cataaagcgg ttactattaa taggagacaa atgcaaggct
    14221 ttaaaagtaa tcaagaaggc aagagaagaa aaaattttta acgaatttct tttttgaaat
    14281 atatgttatt atatcatttt tgttttttct attgtatata tgacaactat gttcaattaa
    14341 aatttagaaa gtgagaaact attgtgtata ctattataaa atcaaatata aaaaaattta
    14401 gtttattaac gatatttatt gttgctggtc aattattgct aatttatgca gcaactatta
    14461 atgctctggt gttgaatgaa ttaattgcga tgaatttaga gcggtttttg aaattgtcaa
    14521 tctaccaaat gattgtctgg tgtgggataa tattccttga ctgggtagtg aaaaattatc
    14581 aggttgaagt gatccaagag tttaatctag agattcgaaa tagagttgcc acagacatct
    14641 ctaactctac ctatcaagaa tttcatagta aatcatcagg aacatatctt tcgtggctaa
    14701 ataatgatgt tcagacttta aatgatcagg cttttaaaca acttttttta gtaataaaag
    14761 gaatttctgg tactatattt gcagttgtga ctcttaatca ctatcattgg tcattgactg
    14821 tagccacctt gttttcatta atgattatgc tacttgtacc aaaaatcttt gcatcgaaaa
    14881 tgcgagaagt tagtctaaat ttaactaacc aaaatgaagc ttttttaaaa tctagtgaga
    14941 ctatattgaa tggatttgat gtgttagcgt ccttgaatct tttatatgta ttgcctaaga
    15001 aaattaaaga agcaggaatt ttattaaaga tggttataca aagaaagaca actgtagaaa
    15061 cgttagcagg cgctattagc ttctttctca atattttttt tcagatatct ctcgtttttt
    15121 taacaggcta tcttgcaata aaaggaatag tgaaaattgg tactattgaa gcaataggag
    15181 cactaacagg tgttattttt acagcgctag gtgaattagg aggtcaatta tcctctatta
    15241 ttggtacgaa gcctattttt ttaaaattgt attcaattaa tccaattgag tcaaataaaa
    15301 tgaatgatat cgaaccaaat gaggtgaata gagattttcc gttatatgaa gcaaaaaata
    15361 tttgctataa gtatggagat aaagaaatat taaaaaactt aaatttttgt tttcaacgta
    15421 atgaaaagta tttaatttta ggtgaaagtg gaagcgggaa atctacatta ttaaaattat
    15481 tgaatggctt tttgagagat tatagtggag aattgcgatt ctgcggggat gatataaaaa
    15541 aaacctccta tttaaatatg gtttcgaatg ttctatatgt agatcaaaaa gcttatttgt
    15601 ttgaaggtac gattagagat aatattttat tggaagaaaa ttatactgat gaagaaatac
    15661 tacagtcttt agagcaagtt ggtttgagtg taaaagattt tcctaataac attttagatt
    15721 attatgttgg tgatgatggg agattactgt caggagggca gaaacaaaaa attactttag
    15781 ctagagggct aattagaaat aagaaaatag tattaattga cgagggaact tctgctatcg
    15841 ataggagaac ttcgttagcg attgaacgta agatattaga tagagaggat ttgactgtca
    15901 ttattgttac ccatgctccg catccggaac ttaaacaata ttttactaag atatatcaat
    15961 ttccaaagga ttttatttaa gaatataggg gagggaaaca tgagattcta ttgtgaagct
    16021 tatgaggtaa ttactgaaga gaaaaaagta tactttaatg atattgagtt agaagttaag
    16081 tattcctctg tcgaagaatt gtttataata tgtgagaaat tattagataa gaaaaaagta
    16141 tcattttttt atgtagatga gaaaccctta aggtatctgt tatttgacta tatatttcta
    16201 ctagttctag ctaaaaaaat atcccaatct tatgaactgc accccaaaag ttagatttat
    16261 tctgtctaac ttttggggtg cagttcattt tgcatagttt tggcattcat cctagatatc
    16321 catataaaat gtctgagatt gttgaaatgt ctaaaaaaat atcagatcta aacgataaaa
    16381 aagaatttca caaaaagaac tgtgagttga ggtttcaaga tagtgttctt gataacataa
    16441 atagtgtccc gggtacaact catttattta gttgtttaaa tattcaaaca ttagtaaaaa
    16501 ttattttata tatttttcga tacaacagtt gtatgaaaat atttaatttt agagataaag
    16561 agcttatctt ttttaataag attgtaaatg ggctgataca aaatattgag gagaatttag
    16621 aggatgatat tgaaaggata ttgaaatatt tatatatatg tttatttaac gaaatattca
    16681 ttattaagaa taaggtgaat ttttttgatg atgtggaatt taatcagaca cttagtgagt
    16741 ttttagataa attgtagagg gaatggttat gagtaacaat actaagtata tctttttatc
    16801 tccacattta gatgacgcaa ttttttcctg tggtgattat atttcaaaat taacttcaga
    16861 aggagaaatt gtacttgtta ttactatatt ttctggttac cctttgagcc aacagctaca
    16921 gccctctgct aagcaatttc ataagttgtg taaccttggg aaatatccga ttgaagaaag
    16981 gaagaaagaa gacaggttag cttgtgaacg tctacaatgt gattttagac acttatcgta
    17041 ctatgaatgt ctctatagga aagatagaaa tggcaatttt ctataccgtc atatctatag
    17101 tgaattaaaa aatgaggaca cattaaagaa tgatatcata aaagagctgt taatgcattt
    17161 agacgacaaa tgtgtcgtat attgtccgct ttcacttggt gaccatgttg ctcatgtttt
    17221 tgtgaatagt attggaaggg cgcttgaatt tatgcgttat aaagtaatat attatgagga
    17281 cttcccatat gtaagtgata gtagtatggt tagttatatg ggaaaaacta aagaattaaa
    17341 aatgtatcaa gaggaacttg atgaaaaaaa ttatattgat agaatatcat caatattgtg
    17401 ctataaatct cagattttga taatctggaa atcagttgaa aaacttttaa acaatattaa
    17461 agagttgtat ttaaggaatg gggcagctta ttctattaga ttttggatta agaaataagg
    17521 aagtagtttt atgaatatag cagtaattgg tttggggcat gttgggctgg cctacgcgtt
    17581 actatttgca tctaaatata aagttgttgc atatgatata gattctgtaa aaataaataa
    17641 tttaaaaaag gcattcttcc atctaaaaat gaagagctta tgaagttttt ttgcgagaat
    17701 aacttaaata ttactttttt tgatacattt tctgaaatta aaaataatat tgattattat
    17761 attattgcgc ttccgacaga ttatgatgag aaaattggta gttttaatac atatgaaatc
    17821 gaacaaacgg tatcgaagat tctgagggta aaacctaatg gaaagattat tttaaagtca
    17881 acagttccga tcggcttttc aaacaaatta aaaaggctgt ttgatacaaa aaatatcatt
    17941 tttgtccctg aatttttgag agaaggttgt tctatatatg ataatttata tccaagtcgc
    18001 atagttgttg gagatgagac agttgaagga agaaaaattg cagagttgtt cctttcgatt
    18061 agtactcata gtactgccaa tattaaaaat gttatgttag tttctcctac tgaagcagaa
    18121 gcaattaagc ttttttctaa cacattctta gctctccgtg ttgctttttt taatgaacta
    18181 gattcttttg ctgagaggag aagtttaaat gctgaagttg taataaaagg tgtttgttta
    18241 gatccaagaa ttggaaattt ttataataat ccttcttttg gatttggagg atattgtctt
    18301 cccaaagata ctaaacaatt aaaaaaagaa tttatagaaa taaatgcccc agtgatagaa
    18361 gcgattgata tttcaaacac aaatagaaaa cagttcatag ttaaacaaat attggaacga
    18421 aagccaaaga tagtaggaat atataaattg gggatgaaat ataattcaga taattacaaa
    18481 gagtcagcta ttttaagtat aattaatgaa ctattgattg tcggtataaa aattttagta
    18541 tatgaaccaa atttaaacgt tagtatagat aacgtaattt ttgaaaagaa ttttgaacta
    18601 tttacaaaac aaagtgatct aattgttgca aatagatggg ataggggcct tgaagcttat
    18661 aaagataaag tttacacaag ggggatctgg ataagagatt aactattgat attaaaaagg
    18721 caataattta taaaatttgt acaaaaaaat gttaaatttt cacattttca tagtatactg
    18781 tttaatagaa agtaggttct ttgtaaccgc tccattataa aatcctttca ctcttccggt
    18841 atactattag gaaaaacata actggaggat attttgagct cacacctcat cgttccagtg
    18901 gctgttcccc caagctcgtg tactgcccaa aaaagttaga cattctattt agaacgagga
    18961 ttgagttctg tattgtacaa ggctcggtcc ttttagagtc agcttaaggc tggctttttc
    19021 aatcaccaaa gtgtcagaat gttttgacaa atgaacacaa ataatgatat aatatgcaaa
    19081 agctaggagg tggtaggatg attgaaaaaa tggaactggg ggaattttac aaggaattac
    19141 gtttggcgag aaagcttaag cagacagatg tggcttgtga gggtctaaca gcttctcagt
    19201 tgtccaagtt tgaactaggg cagtctatgc tgtctgcgga taagttgatt ctagctatcc
    19261 aaggtataaa tgtgaccttt gatgagtttg ggcacaagct caacaactat caagaatctc
    19321 cacatatgcg aatcggtcga aaggttgtga atcgctttgc ccatcaggat atagctgctt
    19381 tagagcagct attggaggaa gtcgatcaag aacagatggc gcagacctat cgtcgtttga
    19441 atgccatcgt gattaaagat gccatccatt cactaaataa aagctaccca ctagcagagg
    19501 aggatagcga gtttttgacc acctatctct atgatatcga gtcttggacc tggtttgaac
    19561 tctatctctt ttgcaatacc atgcccttct tgagcaatca agatctgatt tttttatcaa
    19621 cctccttact cgaaaaatcc aaagaattta aagagttagt acacaatcga ttgtatatga
    19681 agcaaggact cttaaatatc ttatcagaac tcatggagcg aaaacttttc tcctacatcc
    19741 caatctttga agccgagctg gagagtatgc tccgtccata cgatgttttt gagaaattat
    19801 tgtggcagtt tttaaagaag atgagcattt tccttcaaac taagggaagc aatcaaaaag
    19861 agattgaaca ctttatccaa tctctgcaag tattagaaaa tccacaatta atagcccttt
    19921 ttgaattgcg tttgcagcaa tacaaaaagc ttatcgatta gttagaaatg gcaaaataat
    19981 aataatctca gcaacgattt tcaataatgt taaaatttgt ttcttcatat ttctccactc
    20041 ctcattagta gtaactttat tataccagag aagtaatcaa attcaccaaa atcgcaaatc
    20101 tgaaatttct ataagaaaaa atatcaaata tgcgattttc taaaataagc caattttcgt
    20161 gttatactgt acttgtaaag cacttgaagc aaatcctagg tcgcagaagt ggtttacaaa
    20221 tgaagataat tgaaggagtg taaaagatgt taaatttaca atttgcagaa acaatggaat
    20281 tgacagaagc tgagttgcaa gatgttagag gaggcaacct cgtaaattct atgggaggtg
    20341 gtggaagaag tggtatatct ggttggggcg tcccaggaat ttaccctggt tggggcaatc
    20401 aagggatgag tcctaatcgt ggagcttttg attggactat agatttagca gatggattgt
    20461 ttggccgccg tagaagatag gctcttatag gagataatag gatgaagaaa atgaaagaag
    20521 tgaaatttca cctagcaact ggcttgttga ttttgactta ttacctcatt tttaatgtca
    20581 catcagactt agattttatg gttgctttgt ctgataatat gtactatgtg ttccaagttt
    20641 tattggtact tattctggga actatagcta caattgcttt tgtcaaaagt gaacattgga
    20701 aagagtgtgg tcgtttccag tttcgttggt cttacctggg tgttttcctt ctttcttttt
    20761 tcttattgtt cgtgtgggca aatctaacaa cctatatctt tcctcgtacc cagaatggaa
    20821 gtacagtcgt agaagtagcc accaatttaa caggaattag ctattttgtt acgcgaatac
    20881 tttatactag tattatcgca cctgtatcag aagaggttgt ttgtcgtggt cttttgatga
    20941 caagtttatc taaagttaag agatactatc ttgatgttct tgtttccgct gccatatttg
    21001 gcgctatgca tgttttgcag tatggttgga taacgacaga tttcataaag tattttggaa
    21061 tgggcttgat attttgtatg atgtttcgct acacccgatc catctattgg gctatagctc
    21121 tgcatgcttc atggaatagt ttcttactca ttgttacttt attggtattt ggatattaga
    21181 aaggtgatat atgaaaaaga taatctcaca ccgctacttt attatagttt ttctactagt
    21241 tattgctgac cagaagttca gtgttctagt tttacgcagc gaccttgtta ctgggctatc
    21301 tgactttgcc tattatctgt cggatatgat gttgaatttt cttgtggttt tatttgctct
    21361 tattgctatg atttggtcgg ggaaatggca gaaaatcaat agtagaaagt ttaaaggatc
    21421 ctatcttttc tattccttcc tagctctgct tgcttttgtt gtttggaatt tcgttacctt
    21481 ttttcttttc ccacctactc gaaatgaaat ttcttatcaa catgctgctc cgacttttac
    21541 aggggctaca gcatttttga tgtatttttt ctatcctgtg attgcaggtc ccatttttga
    21601 agagataatc catcggggat tggtgatgac agctctggaa aaaggaaaga aatgggggct
    21661 agatgtactt ggttccgctg ttttatttgg ggtctcgcac attagtaatc acggttgggt
    21721 cttgacagac tttgtcttct atatgggtgg aggtcttata tttgcagtct tatttagaat
    21781 gacaaagtca atttattggc ctattggact gcatatagtc tacaatggca ttggtcagct
    21841 tttgatgtta ctgtaatttt ggttgttagt agtatcgcgg tctatccttg gggaaagctt
    21901 cccatttgaa tttaagaagg agttgtgatg aaagtatttc ttcaaaatag agattttaga
    21961 caattaacca tcaaccagtg gatttcaacg cttggggata cgatttttta tctggccttc
    22021 ctgaattatg tggcagatgc atcttttgcc cctttggcga ttttactcat cacgatttca
    22081 gaaaccctgc cccaagttct acaaatcttt ctgggagttt tggcggattt tcaacatcat
    22141 cgtgtcttga aatacacagt cattagtttt gcaaaatttt tgctttactc tatagtgtct
    22201 ttatcacttt cagggcagtc tttctccttg ttgctagtag catttatttg tctgattaac
    22261 ctcttgtctg acacattgag ttatttttca ggcgccatgc tcactccgat tttcattaga
    22321 attattgggc aagaccatct ggcagaagct attggcttta aacagtcaac tgttagttta
    22381 gtgaaaacaa tcagtaatat cctaggagga gtcttactag gcattctatc catccagttt
    22441 atttccttac tgaacgctct taccttttta atcgcatttt taggtatcct cttcataaaa
    22501 actgacctct tgaaagtaga aaaaacgatt agctatcaag aaggactctc tgtaaaatcc
    22561 ttttgccagc atttgctcca atcatcgaaa ttgatatgga atatgaataa ggtgctcttg
    22621 gttttgttta ttatctctac tagtcaagca gtgataaatg ttacggttcc tatttccact
    22681 ctatttttaa ggaaccagcc ctttttgaat ttacaaacag gtcaatctct tgccttgtta
    22741 gccacactag aattgtcagc tcttattttg ggaagtctga tgagtggcta tctgcaacat
    22801 accatttcca taaaaatagc cctgtatgct tcactcctac tccaattact actcctagtg
    22861 ggctttgcga cagctcattt tggcttgatt ctgatcttta gctttttgga tgcctttttc
    22921 gcgggtattc tctctcctag attgcaagaa ctcgtcttta aacaaatacc tgaggagtca
    22981 atgggagcag ttcaatcttc tatcggtgcc attacggttg ttttacctag cttatttaca
    23041 atagctttgg taaccattgc tactagcttt ggaactctgg cagttagctt tgttttattg
    23101 ctatttcttc tagttgcctt tgtcatgctt ctgaatattc gtgaaagtat ttagtggaga
    23161 atttctataa tatatgtttg agactggatt gccagtcttt ttatgatggt caaaatcaac
    23221 agactttttc tcttttctga atgtg
//
LOCUS       DAVHBD010000037        23017 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000037 DAVHBD010000000
VERSION     DAVHBD010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.037"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(369..578)
                     /locus_tag="VVK04_001535"
     CDS             complement(369..578)
                     /locus_tag="VVK04_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEU3990171.1"
                     /translation="MFNYKIVDNQELSNISGGGLGGDVVVGALSGAFQAGQSCIAGGP
                     QAYLICATGGAIVGGILAYGLRPPK"
     gene            complement(594..842)
                     /locus_tag="VVK04_001536"
     CDS             complement(594..842)
                     /locus_tag="VVK04_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEU3990172.1"
                     /translation="MNTKMMSQFSVMNNEMLASIEGGTDWGTVGKGAVYGAGIGVAMC
                     AVGGLLTGGSTWAMTAGCAWAGAKLGGSFTAIADNLWP"
     gene            1119..3272
                     /gene="blpA"
                     /locus_tag="VVK04_001537"
     CDS             1119..3272
                     /gene="blpA"
                     /locus_tag="VVK04_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEU3990173.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            3283..4644
                     /locus_tag="VVK04_001538"
     CDS             3283..4644
                     /locus_tag="VVK04_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU3990174.1"
                     /translation="MNSNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDTIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4701..4856
                     /gene="blpC"
                     /locus_tag="VVK04_001539"
     CDS             4701..4856
                     /gene="blpC"
                     /locus_tag="VVK04_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU3990175.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(4901..6241)
                     /locus_tag="VVK04_001540"
     CDS             complement(4901..6241)
                     /locus_tag="VVK04_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU3990176.1"
                     /translation="MYIFWIILYTLITNGLEIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(6254..6991)
                     /locus_tag="VVK04_001541"
     CDS             complement(6254..6991)
                     /locus_tag="VVK04_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3990177.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6996..7334)
                     /locus_tag="VVK04_001542"
     CDS             complement(6996..7334)
                     /locus_tag="VVK04_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3990178.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7612..7941
                     /locus_tag="VVK04_001543"
     CDS             7612..7941
                     /locus_tag="VVK04_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU3990179.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8110..9159)
                     /locus_tag="VVK04_001544"
     CDS             complement(8110..9159)
                     /locus_tag="VVK04_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990180.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSILAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQAVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9156..9887)
                     /locus_tag="VVK04_001545"
     CDS             complement(9156..9887)
                     /locus_tag="VVK04_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990181.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9955..10365
                     /locus_tag="VVK04_001546"
     CDS             9955..10365
                     /locus_tag="VVK04_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU3990182.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10375..10662
                     /locus_tag="VVK04_001547"
     CDS             10375..10662
                     /locus_tag="VVK04_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990183.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10824..11108
                     /locus_tag="VVK04_001548"
     CDS             10824..11108
                     /locus_tag="VVK04_001548"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990184.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTDEVSSKHCFEVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(11420..12556)
                     /gene="dnaJ"
                     /locus_tag="VVK04_001549"
     CDS             complement(11420..12556)
                     /gene="dnaJ"
                     /locus_tag="VVK04_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU3990185.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12900..13304)
                     /locus_tag="VVK04_001550"
     CDS             complement(12900..13304)
                     /locus_tag="VVK04_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEU3990186.1"
                     /translation="MDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARYREI
                     ILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGMIWTVV
                     VFLMINWNYIANTKKRQKYINISVLIGYLKSK"
     gene            complement(13315..15138)
                     /gene="dnaK"
                     /locus_tag="VVK04_001551"
     CDS             complement(13315..15138)
                     /gene="dnaK"
                     /locus_tag="VVK04_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU3990187.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALADLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15618..16142)
                     /gene="grpE"
                     /locus_tag="VVK04_001552"
     CDS             complement(15618..16142)
                     /gene="grpE"
                     /locus_tag="VVK04_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU3990188.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(16169..17203)
                     /gene="hrcA"
                     /locus_tag="VVK04_001553"
     CDS             complement(16169..17203)
                     /gene="hrcA"
                     /locus_tag="VVK04_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU3990189.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17367..17876)
                     /locus_tag="VVK04_001554"
     CDS             complement(17367..17876)
                     /locus_tag="VVK04_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU3990190.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            18483..20816
                     /locus_tag="VVK04_001555"
     CDS             18483..20816
                     /locus_tag="VVK04_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU3990191.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSIRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKIMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKIDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20829..22292
                     /locus_tag="VVK04_001556"
     CDS             20829..22292
                     /locus_tag="VVK04_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU3990192.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGEGVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            22292..>23017
                     /locus_tag="VVK04_001557"
     CDS             22292..>23017
                     /locus_tag="VVK04_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU3990193.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRI"
BASE COUNT         7334 a         4678 c         4213 g         6792 t
ORIGIN      
        1 tcaaaaaaga aaggacgaaa ttcgtccttt ctcgatctta gattttcttc aactcactac
       61 agttgacaat gagccaaagg atagctaata acctattgaa gtgtcaaacg ttgctaactc
      121 catttatctt caaatttaaa taggcacatt atcggagtta tcagtaagaa aaaatctaac
      181 cagttcagat aattcataat ataggatata ataccagcca taacgaaaag gtacaaagct
      241 gtacgatatc ctctcttttg gtttttatca gccttggtgt taaaaataat gtacacacaa
      301 caaattgcaa tgagtacaag ctgaatcata gtttcattta acatattaac actcattcct
      361 ttttaaaact attttggtgg tctcaatcca taagctaaaa tgccacctac tatagcgccc
      421 cctgttgcgc aaatcaagta agcttgaggg cctccagcaa tacaagattg tcctgcctga
      481 aatgcacccg acaaggctcc tacaactaca tctcctccca atccacctcc agaaatatta
      541 cttaattctt gattatctac tattttgtaa ttaaacataa tttctattcc cttctatggc
      601 caaagattat cagcaattgc agtaaaagaa ccaccaagtt tagctccagc ccaagcacag
      661 ccagcagtca tagcccatgt ggaaccacca gtaaggagtc ctcctaccgc acacatagca
      721 actccgatac ctgctccata gacagctcct tttcctactg ttccccaatc agttcctccc
      781 tcaatgctag ccagcatttc attattcata acagaaaatt gtgacatcat ttttgtattc
      841 atgacaaata ctcctttttt atttttgtct tgttgcaact ttgacaagtt tagtatatca
      901 tttttttttt aaaatttttc atccaaatct tgaattgtca tcgaaacgtc ttgaattagc
      961 ttttcatttg aaaccacctc taaatgtttt aaaaaaaaaa taatttctaa tcactttttt
     1021 accattcagg aagtttcaat gactattcaa gatttaataa aatatgaact tagttttatg
     1081 gcataatata cctatccact atatgaaagg aattgccaat gacttcttat aaacgtacat
     1141 ttgttcctca aatagatgcg agagactgcg gtgttgctgc cttagcctcg attgctaaat
     1201 tctatggttc agatttttct ctagctcact tgagagaact tgcaaagacc aataaagaag
     1261 ggacgactgc tcttggcatt gtaaaagccg ctgatgaaat gggctttgaa acaagacctg
     1321 ttcaagcaga taaaacgctc tttgacatga gtgatgtccc ctatccattt atcgttcacg
     1381 ttaacaaaga aggaaaactc caacattact atgttgtcta tcaaacaaag aaagactatc
     1441 tgattattgg tgatcctgac ccttctgtaa aaatcactaa aatgtcaaaa gaacgctttt
     1501 tctctgaatg gactggagta gctatttttc tagctcccaa acccagctat caaccccata
     1561 aagataaaaa gaatggtcta ctaagcttcc ttcctctgat tttcaaacaa aaatctctca
     1621 ttgcttacat tgttctctca agcttattgg tcactattat caatataggt ggttcttatt
     1681 atctccaagg aatcttggat gaatacattc caaatcagat gaaatcaact ttaggaatca
     1741 tctcagttgg tctggttatc acctatatcc tccaacaagt catgagcttc tccagagatt
     1801 atctcctaac cgttctgagt cagagattaa gtattgatgt gattttatcc tatattcgcc
     1861 atatttttga acttcctatg tctttctttg caacacgtcg tacaggagaa atcatttcac
     1921 ggttcacaga tgctaactct attatagatg ccttggcttc taccattctt tctctttttc
     1981 tggatgtttc tattctgatt cttgtagggg gcgtcttact ggcacaaaac cctaatctct
     2041 tcctcctttc tcttctttcc attcctatat acatgttcat catcttttct tttatgaagc
     2101 ctttcgaaaa aatgaaccat gatgtcatgc aaagtaattc tatggttagc tctgccatta
     2161 tcgaagatat caacgggatt gaaactataa agtcgctcac gagtgaagaa aatcgctatc
     2221 aaaatataga cagcgaattt gtagattatt tggaaaaatc ctttaagctc agtaaatatt
     2281 ctattttaca aacgagttta aagcagggaa caaaattagt tctgaatatc cttatcctat
     2341 ggtttggcgc tcaattagtc atgtcaagta aaatttctat cggtcagctg attaccttta
     2401 acacactttt ttcttacttt acaactccta tggaaaatat tatcaacctc caaaccaaac
     2461 tccaatctgc gaaggtcgct aataaccgtt tgaacgaagt ctatctagtc gaatctgaat
     2521 ttcaagttca agaaaaccct gtccattcac attttttgat gggcgatatt gaatttgatg
     2581 acctttctta taagtatggt tttggacgag ataccttaac agatattaat ctcacgatta
     2641 aacaaggaga taaggttagc ctagttggag ttagtggttc tggtaaaaca actttagcca
     2701 aaatgattgt caatttcttt gaaccctaca aagggcatat ttccatcaat catcaggata
     2761 ttaaaaacat tgataaaaaa gtcttgcgcc gtcatattaa ttacctaccc caacaagcct
     2821 atatctttaa tggctctatc ttggaaaatt taaccttggg cggtaatcat atgattagcc
     2881 aagaagatat tctaagagct tgtgaattag ctgaaatccg tcaagacatt gaaagaatgc
     2941 ctatgggcta tcaaactcag ctctctgatg gagctggtct atcaggagga cagaagcaac
     3001 gaatagccct cgctcgtgct cttttaacta aagctcctgt tttaatacta gatgaagcta
     3061 ctagcggtct tgatgtcttg actgagaaaa aagttataga taatcttatg tccctaactg
     3121 ataaaaccat tctctttgta gcccatcgtc tcagtatagc cgaacgaacc aaccgtgtca
     3181 ttgttcttga ccaggggaaa atcattgaag ttggtagcca ccaagagtta atgcaggcgc
     3241 aaggcttcta ccatcatcta ttcaataaat aaggagaatg tcatgaattc taatcttttt
     3301 agaagcgtcg agttttatca gagacgttac cataactatg cgacagtgtt aattatacct
     3361 ctttcattac tgtttacttt catcttgatt ttctcccttg ttgccacaaa agaaattact
     3421 gttacttccc aaggagaaat cacccctaca agtgtcattg catccattca gtcaaccagt
     3481 gataatccta tccttgctaa tcatttagtg gcaaatcaag tagttgaaaa aggtgactta
     3541 ctcatcaaat actctgaaac aatggatgag agtcagaaaa ctgccttaga aactcaatta
     3601 caaagacttg agaagcaaaa agaaggactt ggaattttga aacaaagttt agaaaaagcg
     3661 actgatcttt tttctggcga ggatgagttt ggctaccata atacttttat gaattttact
     3721 aaacaatccc atgatattga actgggtatc tcaaagacta acactgaagt ttcaaatcaa
     3781 gctaatctta ccaatagcag ttcatcagcc atcgaacaag aaattacaaa agttcaacaa
     3841 caaattggag aatatcaaga gctgagagat actatcgtaa ataaaagagc tcgcttacca
     3901 actggcaatc cgcaccagtc aattttaaat cgttatctta tagcctctca agaacaaaca
     3961 caaggaacgg cagaggagcc atttttatct caaattaatc aaagtattgc aggtctggaa
     4021 tcatctatcg caagcctcaa aattcagcaa gctggtatcg gaagtgtagc aacttatgat
     4081 aatagtttag caaccaaaat tgaagtactc cgcactcagt ttttacaaac agcctcacag
     4141 caacaactaa ccgtggagaa tcaattaaca gaattaaaag tacaactaga tcaagcaacg
     4201 cagcgcttag gaaacaatac cttaaccgct ccaagtaaag gtatcgttca tctgaacagc
     4261 gaatttgaag gtaaaaatag aattccaact ggtacagaaa ttgctcaaat attccctgtc
     4321 atcacagata caagagaagt actaatcact tactacgtat cttctgacta tctacctcta
     4381 ctagataaag gacaaactgt aagattaaaa ctggagaaga ttggaaatca cggcaccacc
     4441 atcatcggcc aacttcagac aattgatcaa actcctacca gaacagagca aggtaatctc
     4501 tttaaattaa ccgctcttgc aaaactatct aatgaggata gtaaactcat ccaatatggc
     4561 ttacaaggtc gcgtcactag tgtaactgca aagaaaacat attttgatta tttcaaagat
     4621 aaaattttaa cccattctga ttaattttca gataacactc tataactatt tattatctta
     4681 tcaaaaagga gaatcataac atggataaga aacaaaacct aacttcattt caagaactaa
     4741 caactaccga actcaaccaa attacaggtg gaggactgtg ggaagatatc ttatacagcc
     4801 ttaatataat taagcataac aatacgaaag gacttcatca tccaatacaa ctataaaaaa
     4861 taagaccgag taacaagaac tctcggtctt atttttttca tcattctgta ggtatcatag
     4921 taagcacctg acgaaagact tgatcttgac aggtagtatt taaactggca ttgggataac
     4981 tttccacaat cttcataacg gtatagagac cgacacctct ctcctcccct ttagaactaa
     5041 ctccaaagga gaagatttca gaaatatcga tgccctcttc tttgatggaa ttttcgatga
     5101 tgaaggtctc ctgtgctcca ctttttaaaa aggcaattga aacatgaggt tgaccggcct
     5161 ctgcactcgc ttcaatagca ttatcacaaa ggatagacac aatggttaga aaatcaagca
     5221 gtctcatccc ctcaacctga atctcttcag gaacttcgac attaaagaca atgtcctttt
     5281 ctctagcttt tataaatttt ccagctagga gacttttgag ggcacgatcc cgaacattca
     5341 ccaatcggcc aaggtcatat ttattgtcct gcaatttttt actagaatcc tttaagacca
     5401 agtcatagac ctcttttatc tgctccatat cctcctcttc aatacccaga cgtaaacttg
     5461 tcaagaggtt ggtgtagtca tggcgaaaac tccttacttc cttgtaaagt tcctctatat
     5521 gccgactata gcgttccata tctctatagc gcaagacctg ctcttggtcc agtctatcat
     5581 ggagtttgtc cttcaaatag gtatccaatt tcttgataac ccccataaaa aataggaggt
     5641 aaaacactag gatgagatgg cgaacagtcg ttgattgaat accttgctca tattcaaagt
     5701 aagacagact ttgtatcacc aaatagtaag cccccattat ccagttaatc ttagtcaggg
     5761 acttttgaaa acctgtatct agaatctccc ttctcaaact agtaaaatca tagtccaacc
     5821 atttcaaaaa ggctagagaa atgaagaaat tgaaaattat tatacataac ccagtaaatg
     5881 agtagccatc atatacttgc tcttgtccca aaaatggaag cacaaaatag gagactcctc
     5941 tataaaagag attcaccaat atcattggaa agagaccata aaagaaaagg agttttttag
     6001 gaagccctct taacaataag aaagacaagc ctatgccgta caagggttcc ataaaataag
     6061 ataggtaaac atttcctacc atatagccaa tcattacaaa aacaaaggcc aacagtatct
     6121 tcaaaagaaa ggccttaaaa atcctctcaa aagtgagacc aattccatct accttaaaga
     6181 aaatgacaat ttctagccca ttagtaataa gtgtatacaa tataatccaa aaaatataca
     6241 taaatttcct agttcagtgt aagttattaa tagcctcaga cacttccctg accttataac
     6301 gcgcgatcag acagcttcca ccattgggaa agaaaaggag tttttctttc ttatccaaat
     6361 gcaccacatt tgcaggattg atgagaaaag agcgatggca ctgcaagaga cggggttcct
     6421 gcttaaaaac ctcctctaaa ctcgccgtaa attctagcct gtccgtcttg gtatagagaa
     6481 taacacgatg gggtcttggg gatgtttcga gatagtaaac ctctttgaaa ggatattgga
     6541 attgggcaaa ttttgattta aagtaaaagc aatcttccgc cagactttta ctatcttgac
     6601 tattggcata gaggagggct gtctcgatac gagattcaaa ctcctctgcc gaaagggcct
     6661 tatcaatata gtccagagca gacacttggt agcgaaagga cagaggcata aactccgagt
     6721 gagtcgtcac aaagacgatt agggcataag ggtcttgttc ccgaatcttt ctagccactt
     6781 ccagtccctt catctcttca tttcgaatct caatatccaa aaagaatagc tgatgggccc
     6841 ccttctcatg cacctctgcc agcagttggt ccggcttgcc aaatacctca aaagagctag
     6901 gaatgatatg atgtgctttc aaaagtttct caatcgtcgt ttcaattcta gtctgttggg
     6961 aaaaatcatc ttctaaaaca aatattctca tcttcttact ctccctcttt caaccatttt
     7021 tgacgaattt ctctatagcg acgtctggca tacttgacag cgtattgacc ttcttctccg
     7081 agaaaaagga ttctttcttg aaaatcaatc gattttaatt tatcaagatt aaccaaacaa
     7141 tttcgatgac atctcatcaa ggtttcccca cattggttct caagattact taaattttga
     7201 agcatattaa aactagcttt ttctgtaaca atctgtacgg tatgggcttt agttggatgt
     7261 gtttggatat agtagatatc gtcgacgttt actttataga ctgttttctg cgtctgaata
     7321 atcatatgtt tcattggatt ctcctcctaa gaaaagaata acagaaaagt tctagcccaa
     7381 gcccacccaa tcctaaacag tctttgaaag ctcctaaaag gattattttt ctacaacatc
     7441 atgatgagct tacaactatt ttatcataaa attcactcag cgcaattcaa gacatttcaa
     7501 tgacaattaa agatttgaat aaaaaaaaaa gaattaaaag tgataaacta acagtatcaa
     7561 aacacagttg ccagaagtaa gactggcacc cagattaaag gaggcattcc catgacagat
     7621 acagacccca tcaaaagagc tcatactttg attactgact taaacaaagc ctaccaagca
     7681 tgcaaacagg caagtgctga cgacgtccgc tttcaggagc aattaaactc tattcttggt
     7741 tttctagcca aggctgaaac agtggataat cgattcttga ttgaactaga aaaattttac
     7801 cagacttcca gtcttctcat gggactcagc gctcttgatc cagatgctcc aactcgcgcc
     7861 gcttggcggg cctatgaccg cttccacttt gaccaagtca agaccaagtt aatactcaat
     7921 gaaaatcaaa gagcaaacta ggaagctagc cgcaagctgt acttgagtac ggtaaggccg
     7981 acgctgacgt ggtttgaaga gattttcgaa gagtataagt ctctacggac caaccattat
     8041 cctgtagtaa caaaaaagaa gctgagacaa actgaactca acttcttttt tagtgtcata
     8101 taggcaagat taatcctgca tctgacgttt tacctgataa ggcaaataca agactagtaa
     8161 aaccaaacca gctcccagta aggctagaag ggctagtttt tcttggaagg taatcaaccc
     8221 aacaactaat tccaccagta aaacaaaact ggtcaatcct cggactacag cctgtaagcc
     8281 tttttccttt tgccccttgt ccagtggaaa gagttgggtc aaatactggt agtcaaaggc
     8341 atgatagagg gccagcaact gaaagagcaa gaggtagtta aagagaacca ccactgctgt
     8401 cgcaatccaa gcttgctcga taaatacctg cgccagtatg gaaagcaaga gcagacggag
     8461 actgagcgca aagaggtctc catttcgcag ataagaacgt agatagagat tttgccaaat
     8521 ctttccaggc accttctgaa cagcctttag gataaagtcc agataggcac gacgcttgac
     8581 gctgtttgaa attcccttga cctgcgtaaa gagggcaaag aaacgaagca agacttgctt
     8641 acgcttgctt tcttgagaaa taacatagtc ccagtccagt ccagtttcag taaaaaattt
     8701 gctggccttt tgacgaaagt ggaaatattt tcctaccccc aataaaagca catatagcag
     8761 aaaaactggc aagccataac ccattgctaa aaataaaggc gcaaataaca gcaagaaaag
     8821 ggtctgtaca aagagccaaa agactaggga aatgccagtt tgacgcttga gatggagctt
     8881 gattgcctct tctccaacta agagaaagag cttgtctgga gcctccatat aggtggcaat
     8941 tcctccccaa agtaagagta aaacagacgt aattcctaca aacaaaagga taggccaatg
     9001 attttcagga aaatgttgta agagttgact gtactggtag gctagaaagc ccaacaggac
     9061 aagcaggaac aagacaaagt ggtcattgag cacatagcgc agataacaaa gacactcctt
     9121 acgaaaggcc tgctttctct ttaaaaacaa gtctttcata gatcctcctc tttggtcaga
     9181 gccaagtaaa tatcattcaa actagcctca ggcatatcaa aggcttcacg tagttgcagg
     9241 agattgcctt tggcacgcac ctctcccttg tgaagaatga caaaggcatc acacatcttt
     9301 tccgccgaat ccagcacgtg ggtactcatg agaatagact tgcccttttg cttctccact
     9361 tccaaaagct gaatcaaatc agaaatagcc agcggatcaa gaccaaggaa aggctcatcc
     9421 acgatgaaaa gacttggatc caccacaaaa gcacagataa tcatgacctt ctgcttcatc
     9481 ccttttgaaa aatgaacagg gaaccagtct aatttctgtt ccaaacggaa catttttaac
     9541 aagggctcta ctcgttcgaa agccactttt tgctcaatac cgtaagccat agcaaccgtt
     9601 tcgatatgct ctctgagggt caattcctca tacagactag gcgtctcagg aatgtagcca
     9661 atctgcttgc ggtagctagt cgcatctcct tgcagagtca ggccattgat attgatggag
     9721 ccactataag gtgccaacag accgataatc tcattgatcg tcgttgattt cccagcacca
     9781 ttgagaccaa tcaaaccgac caactgccca ctttcaacag taaaggacac atctttcaaa
     9841 acaggaacat gaacatagcc acctgtcagg tttttaattt ctaacatatt ttctccaaat
     9901 ctggtataat gtagctatat tatatcaaaa ttcagtacag tagaggtaga ttttatgtca
     9961 gattgcattt tttgtaaaat catcgcaggg gaaattcctg cttcaaaagt atatgaagat
    10021 gagcaggtcc ttgcctttct tgatatctct caagtaacac taggacacac cttggtcgtg
    10081 ccaaaagaac actatcgcaa tcttttggag atgaatgcta cgagcgccag ccaactcttt
    10141 gcccaagtac caaaagtagc tcaaaaagtc atgaaagtca ctaaggctgc tggtatgaat
    10201 atcatttcca actgtgaaga agtcgctggt caaacagttt ttcatactca cgttcacctt
    10261 gtgcctcgct acagtgctga cgatgacctc aagattgatt ttatcgccca cgaaccagac
    10321 tttgacaaac ttgctcaagt cgctgaaacc atcaaaaacg cttaaggagt tgctatgaaa
    10381 ttatccaacc tactgctatt tgcaggagct gcagccggaa gttatctggt tacaaaaaat
    10441 cgccaaacca tcacagatga agtcttgaat accactgacc gcgttcaagc tatcaaagac
    10501 gatgtggata ttatccaaaa tagcctgcaa atcatcgacc agcaaaaaga acttatcaag
    10561 gaataccaag aagacttgac ttacaagttt aaggtcttgg aaaaggatat ccagactaga
    10621 ctagctgtga taaaagaaat gcagggaact gaagataagt aaaaagagcc ccccggctct
    10681 tttttaaaac gtaaacaagt tatagtgaat tgaatttaga atagcacatc atagtttcta
    10741 aagcattgtt agagattact ttaaaatcct cttatcaatt tgttcatatt ctatttcaat
    10801 ctactatata tatcccatca actatgcatc ataatttagg taactcatac tcaataaaaa
    10861 tcaaaaagca aactagaaag ctaggcacag actgctcaaa acaccgtttt aaggttgtgg
    10921 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgtagatacg actgacgaag
    10981 tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt aaccataccc
    11041 atgacaagcc gacgctgacg tggtttgaag aaatttttga agagtatcat tcaccatttc
    11101 acaactaaat cgaagacttt ctgccgtaat gaaaacacct gaaacagctt ggtttcggct
    11161 gtccggaaac tttaagactt aggttcaaag tttaggtatg gaacttcgaa ggaggtcgct
    11221 accgtccgtc attacttagg aaagtcttaa aaaatcggct ctataaagta aaaagagccc
    11281 gacagctctt tttgtttata ttcaatgaaa atcaaaaagc aaactaggaa actagccacg
    11341 ggctgctcaa aacactgttt tgaggttgta gatacgacaa gccgacgctg acgtggtttg
    11401 aagaaatttt tgaagagtat tattctccat caaaggcatc tttaatatgg tcaaagaagc
    11461 cttttttctt tggatttact ttcaagtcac cagcagccgc gaattctttc aaggctactt
    11521 tttggcggtc gttcaagcct gtcggtgtta cgacattaac agtaacgtat tggtcaccaa
    11581 ctgcaccgcc acgaaggctc ggtgccccct tactacgtag gcggaatttc ttaccagtct
    11641 gagttccctc tggaataacc aattcaacat caccgtgaac agttggaata tctactgtat
    11701 caccaagagc cgcttggaca aagttgaggt tgagattgta gaagatagtc gttccttcac
    11761 gttcaaactt gtcgctagct tctacagaaa ctactacata caagtcacca taaggtccac
    11821 cgttaaagcc tgcttcacct tgaccagcga ggcgaatttg ttgacctgtt tccacaccag
    11881 cagggatttt cacatgtacg ctatgagctt gtttctcatg acctgttcca tgacaggttg
    11941 tacatggata tttgatttct tttcctcgac cgtgacagac atcacaggtt acttggcgac
    12001 gcatcatacc aagaggagtc tgcgtatcga cgttaatgac accagcgcca tgacagcgtc
    12061 cacaagtgac tggacttgtc cctggcttag caccagagcc attacatgta cgacagccag
    12121 cttcacgatg atacttaact tccttctcag ttccgaagat agcttcttca aaggtcaaat
    12181 tgacacgata ctggagatca tctccttggc gaggagcgtt tggattgcgc gaagaaccgc
    12241 ctccgccgaa gaaacttgag aaaatatcct caaaaccacc gaagccacct gccccattga
    12301 aaccgccgaa accaccagct ccaccaaaac caccattggc gcctgcagca ccatactggt
    12361 cataggcagc acgtttttgg tcgtcactca aagtctcata ggcttcttga acttccttgt
    12421 acttgtcctc agcaccaggc tccttgttga tatctgggtg atattttttg gaaagcttac
    12481 gataagcctt tttgatttcg tctgccgaag cgtttttgga tacccccaga cgatcataaa
    12541 attcagtatt gttcataatt caagatacaa agggcgtcaa acggacacag ccatctagga
    12601 gttttgacga cggacgctta tgtcctagaa aaaactatct ttttggcaca gtccgtagcc
    12661 cgtgttcagt tacgaacacc cttattcctt tctattgatg ttctgaatcg aaccaccatt
    12721 taggtcggat tcaattcctt tcttttatat ttagtaagaa attctgaaac ccgtgttcag
    12781 ttacgaacac tctttgttcc tttctattga tgagacaaaa cccaaacaaa taagattccg
    12841 tcccttttta tcgaaaaaca gaggctgggt tgcaacctct gcaaataagt aaattaactt
    12901 tattttgatt ttaaatatcc tataagtaca gaaatattta tatatttttg tctcttctta
    12961 gtatttgcta tataattcca attgatcata agaaatacaa ctactgtcca aatcatacca
    13021 attatgaacg gtattacaaa tttatatgtt tgtatttcta atgatatcat agctgatacc
    13081 agcgccgata caaatgcaga caacaatact gaggtaacaa aattccttac cgcttcatca
    13141 tttttgatac aactatcatg ttcagctaat ataatttctc tatatctagc taaatattct
    13201 attggaatat tatcaataaa atcttttgat gttctatagt tatcagcttg attacaaaaa
    13261 tcattataaa cttttcgtgt attttttaga tactcttcat ccaatacact cgtcttactt
    13321 ttccgtaaac tctccgtcta cgacgtcatc gcctgcgttt cctgttgctt gtgcgccttc
    13381 tgctccttct tgagcttgtt gcgctgctgc ggcttgttcg tagagtttaa cagcaagtcc
    13441 ttgagctttt tcgttcaatg cttcaagttt cgctttcatg tcgtccaagt tgttgtcttc
    13501 ttgagctttc ttaaggtcag caagggcagc ttgggcagcg tcacgttctg cgtcgaagcc
    13561 tttaccttca gtttccttga ttgtcttttc agtcgcaaag attgcttggt ctacttcatt
    13621 acgaaggtct acttcttctt tacgtttctt atcggcttca gcgtttgctt ctgcatcttt
    13681 catcatgcgg tcgatttctt cgtcagtcaa acctgagttc gattggatga caatagtttg
    13741 ttctttttga gttccaaggt ctttggcctt aacagacacg ataccgttct tgtcgatgtc
    13801 aaatgttact tcgatttgag gaattccacg aggtgcagct gggatatcag tcaattggaa
    13861 gcgtccaaga gtcttgttat ctgctgccat tgggcgttca ccttgaagaa cgtggatatc
    13921 aacggctggt tggttgtctg ctgctgttga gaagacttgt gatttagatg ttgggattgt
    13981 agtgttgcga tcgataagtt ttgtaaatac tccacccatt gtttcgatac caagtgacaa
    14041 tggcgttaca tcaagaagga caacgtcctt gacatcacca gtaatcacac caccttggat
    14101 agccgcaccc atagcaacta cttcatcagg gtttactgat ttgtttggtt ctttaccagt
    14161 ttcagcttta acagcttcaa caacggcagg gatacgagtt gaaccaccaa caaggataac
    14221 ttcgtcgatt tctgacaagc tcaaacctgc atctgaaagg gcttgacgaa ctggaacttt
    14281 tgtacgttca acaaggtcac gagtcaaatc gtcaaatttc gcacgagtca aagtcatttc
    14341 caagtgaaga ggtccagcct cacctgcagt gataaatggc aagctgattt gtgttgaagt
    14401 tacaccagaa aggtctttct tcgctttttc agccgcatct ttcaaacgtt gcattgccat
    14461 cttgtcagta gacaagtcga taccgttttc tttcttgaat tctgctacca agtggtcaat
    14521 gattttttgg tcaaagtcgt caccaccaag tttgttgtcc cctgcagttg acaatacgtc
    14581 gaagacaccg tcacccaatt caaggataga gacgtcgaat gtaccaccac caaggtcaaa
    14641 taccaagatt ttttcttctt tgtcagtctt gtccaaacca taagcaagag ctgctgcagt
    14701 tggttcgtta acaatacgtt ctacttcaag accagcaatt ttaccagcgt cttttgttgc
    14761 ttgacgttga gcgtcgttga agtaagccgg aactgtgata acagctttgg ttactttctc
    14821 accaaggtag tcttcagcgt agcctttcaa gtattgaagg atcatagctg agatttcttg
    14881 tggagtgtat tcttttccat ttgcagaaac tttttcagaa gttcccatct tagatttgat
    14941 agagataact gtatctgggt ttgtgactgc ttgacgtttt gcagcatcac caacgatgat
    15001 ttctccgttt ttgaatgaga ctacagatgg agttgtgcgg tttccttctg ggtttgcgat
    15061 gattttgctt tcagttcctt caagaactgc aactgctgag tttgttgtac ctaagtcaat
    15121 accgataatt ttagacatgt gtttttctcc ttgttagtta attttctatt tttctttttg
    15181 atactcttct taagtggcga cgccgtcaga gcttgacttc gtcaatctct ttgactaaac
    15241 tttgagccta aggtctcaaa atttgcgcaa atagcgccac ggcgaagagt atcgtgtttg
    15301 gttcgcttcg ctcactatta caaagccaaa catattttat ctttctttat agtttattgt
    15361 cgtttcggac aagttttcta ttctgtaaat tgcgacacga ggagtcgaaa tcgattttat
    15421 ttcgacgacg agttagtaag gaagctaggc aaacgccata tcgattgccg ttttctgacg
    15481 agttgcttta gctaccgtca gaattgccga atcgaacacg ccctaagctc tgagtaaaaa
    15541 agatagattt tcttgtgttc atcgaacact tcgtcaatct cctattttta ctgcgagctt
    15601 tttacgggct ttgtatctta gttatacacc actaccattg ctgggcgtag gatgcggtca
    15661 tggagtttgt agcctttttg aaagacttga gcgatggtat ctactgggtg ttcatcgtct
    15721 gctgggagag tttggatggc catatggtag ttatggtcaa attcgccatc tgctgcgatt
    15781 tcttcaattc cttcttcttt caaagcgtga atcaagcttt cttgcaccat ccccaagccc
    15841 ttcttcacat catctgtcaa accttcaact gcaagtgcac gctcaaggtt gtcaagagat
    15901 ggtaagattg cttttgccaa gtcctggcta cgataacgtt gcaagttttg acgttcttca
    15961 ttggcacggc gttggatatt ttgcatttct gcatgagcgc gaagatattt gttttcgaac
    16021 tcatctgcac gttcatttgc caagtccaac tcagactttt caggagttgt ttcttcagct
    16081 gtttccacaa cttcctcttc ttgaacttct tctacttctt cattttttat atcttgggcc
    16141 atgttcgcct cctttaatga tttcaatctt aatgtacttc gtaatgatta ctgctgaggt
    16201 agcggtaaaa atctgtcaac ttcatggtca aaacacggtt gaccacattg acttgattga
    16261 ttagctgttg gtaatccaga ttaactggac cgataatggc tagaattcca actccccgat
    16321 aaggaatgag gaacttacta ctaatcaccg ctaggtcagc taaacaggac tcttgaccgt
    16381 ctgcaacacg aacattttgc atctgatcct cacgcaaccc ctcacgaatc tccaaggcca
    16441 ccttttgcgg ttggtcaaag aactgatagg cttctagatt ggcaaaattc aagagattga
    16501 ccttgcccgc catcacaatg ttttcgttga acatttcctt aaagatgtgt tcaaagagat
    16561 cgatgacatt atccgttgtt gtaaagtaac gctggataat ctgcggaatc tccgtccgaa
    16621 tcttgtagtg aatatctaaa acggtgtgac cgaggaatcg ttcctgaatg atgctcttca
    16681 gtttcagcaa atcctcctgc aagaagttcc ttggaatcag aaactgacta gtaaccgttc
    16741 gcgactcgtc tagggtaaat accgccaagg ctgtatgttg ccccaaaaca acgatatcaa
    16801 aggctgtcaa acgttgcctg ctcggctcaa catccagtgc cactaccgta cagccactca
    16861 ggtctgttag caagttagca gcctcttgca gaatatcctc caatttgaag aattcctgat
    16921 caaaggcttt gacaatctca tatacctcat tttcagccag ccggtgaaaa tccagtgagt
    16981 gtttcacata gtactgaaaa ccagcaacac ttggcatccg accgcttgaa gtatgagcct
    17041 tctcaagcaa cccttgtttt tctagttccg ccatgtcatt acgaatggtt gcactgctag
    17101 agttaataga ctcttgcaag gcttttgatc cgacaggttc gtgcgttttg gtaaagatgt
    17161 caataatcag atttaaaata tcctgctgac gctctgtaac catctcatca ctcctctctg
    17221 tctgatcaat tagcactcaa tgcatccaag tgctaactta tgattctatt atacaccctt
    17281 agaagagaat gtcaagacaa aaactcaaaa aattagcact cttttatcaa gagtgctaaa
    17341 aatcaatctg aagacctaga accttgctat tcatctactc ggtatttcct ttttagtctg
    17401 aaataaccat gaattagata agaaatcaga aaagcatata aaacaaaaat aagaaagaaa
    17461 gacatagaaa gatcctctct aaacaaactc gtacaaacaa caagaccacc taagaaagta
    17521 gttgtacagg aacgaagtct agatcgcata acttcccatt tgagcccctt actcatatag
    17581 acttgatcct ctggaagtaa atcagaagac gatttacgaa gaatcgaaca agaacctgct
    17641 cctatcaatt cccaacctct atctctaaaa tcttgcagtt catgcttata ttttttaaga
    17701 aatctagaat catagatacg gtagatgaca tcgtctggtt gacattggtc aaaatagaac
    17761 aaaccaaaac gactcgttct atacctccaa cctttcaaat gcatctcatg taaatattct
    17821 tcttccttgt ccaaatcaac aatagtgaaa atccgaaatt ctactctgct attcattgtc
    17881 ttaccccaaa attagaaaac atgcctggcg ttatttatta gataattctt tccacttttg
    17941 actcaatctc caaaaaatat aagaaatctg aatcgcaaaa actatcaata aaacccaatc
    18001 tattatgaaa gtcaaaaaca cttcccaact gaaagaacta cctccagtga caaactttga
    18061 gaaaaacggt agtagagcta aaaagagaag caaaatagga agcatccgca ttgttaaaat
    18121 ccttttggca taaaaaaatc tttatttaaa cgaaaatatt atggcaaaat ttacgccagt
    18181 ttttgaacgg ctgatgtaga tattttatac tttcaaaatg tttaaatgtg attatttatt
    18241 tttgaaaaat agctcaccat cccgactgaa agtgcttata aatgataata agtcgcctgc
    18301 cgaaaacagc gaaaaatagc ggtgttatgc ggagataatc tgacgcgatg cgaaagtata
    18361 ttgcatactt attttcaaca atttagcaga gtatttttat aagtgtgata taatagaagt
    18421 ataatttgtt ctgatagttt attttatgga gaagtagatt tttagaatgc ggaggattca
    18481 atatggttga gtttataaag tctaagaaag aaatgagtga ggaggatatt aaagcaaatt
    18541 tcatcactcc tgctattgta tccaaaggat ggaaaaatgg tgagcatatc gcttacgaag
    18601 aatacttcac tgatggtcga attgaagtta gaggagataa ggctcgtcgt aaagaaggaa
    18661 aaaaatcaga ctattcactg tattaccaat ttggaactcg aattgcaatt gttgaggcaa
    18721 aggataataa acacagcatt cgagcaggat tacaacaagc tattgaatat ggagagattt
    18781 tagatgttcc atttgtttat tcttcgaatg gtgatggctt tattgaacac gaccgtatca
    18841 cgagagaaga acgtgagctg gagttagacg aattccctac tcgtgaagaa ttattttctc
    18901 gtatgacgaa ggaaaaagga ttgacgtacg aaattacaga agctatctca actccatact
    18961 atacagacgc cttctcaatg aaaacgccac gctattatca gcaaatagct atcaaccgta
    19021 ctattgaaac agttgccaga ggacaaaaac gagtaatgtt tgtgatggca acaggaacgg
    19081 ggaaaacgtt catggctttt caaattattc atcgccttcg aaaagctggt ttggctaaac
    19141 gagttttatt cttagcagat agaaacatct tagtagacca aacgatggct gaagacttta
    19201 ggccattcga aaagataatg acgaaaatta caccaaaact tttgactgct cctgaaaaat
    19261 taaattcttt tgaaatttat ctagggcttt atcagcaact aactggtgaa gatggaactg
    19321 aaacacatta tcaaaaattt gacaaagact tctttgattt aatcgtaatt gatgaagcgc
    19381 accgtggttc agctaaggaa aacagtaact ggcgtaaggt aattgattat ttcagttctg
    19441 cgacacaaat tgggatgacc gctactccta aagaaaccaa gaatgcttcc aatacggaat
    19501 actttggtga gccaatctat acttatagtt taaaacaggg aatcgaggat ggttttttgg
    19561 ctccatatcg tgttatgagg gttaatttag atgtggatgt ggatggttat cgtccagaaa
    19621 ctggaaaaat tgatactaac ggacaattaa tagaagatag gtactacggc aggaaagatt
    19681 ttgataaaac cattgtcatt gatgatagaa cgcaaagagt tgccaagttt gtttctgatt
    19741 atatgaagca aagcaatgca cgatttgata aaacaattgt tttttgtgtt gatattgacc
    19801 atgccgagcg aatgcgtgct gcacttgtaa aagagaatct agacttagtc caagaagact
    19861 atcgttatgt catgcaagta actggtgaca acgctgaagg aaaagctcaa ctggataact
    19921 ttatggatgt caattctaat tttcccgcta ttgtaacaac gtctaaatta ttaacgacag
    19981 gagttaatgc taaaacatgt cgtttgattg ttttagactc taatatccaa tccatgactg
    20041 aatttaaaca aattattggt cgtggcacac gtctttatcc tcaaaagggg aaagaatttt
    20101 ttacgattat tgattttcga aatgttacca atttgtttgc tgaccctgat tttgatggtg
    20161 agccagtgaa ggtgctggaa acaggtgcga aaacagtcag tggttctacg cccggtttcg
    20221 tagatgagga aggtgaccca gtagaaaaat atatcgttac agacaagcag gttaccattc
    20281 ttaattctac tgttcaagta ttggatgaaa acgggaaact gattaccgaa agcctgaccg
    20341 actacactcg gaagaatatc ttaggtagct acgccacttt gaacgatttt atcacagttt
    20401 ggcatacggc ggataaaaag aagcttatct tagacgaact ttataaaaaa ggagtttatc
    20461 tagatgctat tcgagagtcg gagggaatat cagaacaaga aatcgatgat tttgatttac
    20521 tcctaaaact tgcctatggt caaaaagaat taaccaaaac ggaacgtatc aataaactca
    20581 aacaaagcgg atatttatat aaatatagtg aggaagcgcg tgctgttttg gaaattttac
    20641 tgaacaaata catggataaa ggtattggag aactcgaaag cattgaaaca ttaaaacttc
    20701 cagaatttca gatatatggt ggaaccttca aaatcatcaa tacttatttt ggagataaaa
    20761 aacgatattt acaagcaatt aaagaattgg agcaagagct atttacagta gcttaatgaa
    20821 aggaaagtat gtcaattaca tcatttgtaa aaagaattca agatatcact cgaaacgatg
    20881 ctggtgttaa tggtgatgct caacgtattg agcaaatgtc ttggttatta ttcttaaaaa
    20941 tttatgatag ccgtgaaatg gtttgggaat tagaagaaga cgagtatgag tcaattatcc
    21001 cagaggaatt aaaatggcga aattgggctc atgctcaaaa tggggaaggg gtattgacag
    21061 gcgatgaatt acttgatttt gtcaataaca agttattcaa agagttgaaa gagcttgaaa
    21121 taacttcaaa tatgcctatt cgaaaaacga ttgttaaatc agcttttgaa gatgcgaaca
    21181 actatatgaa aaatggcgtc ttgttacgcc aagtcatcaa tgttattgat gaagttgatt
    21241 tcaatagccc tgaagatcgt cattcgttta atgatattta cgaaaaaatt cttaaagata
    21301 ttcaaaatgc tgggaactca ggagaatttt atacgccacg tgcagcgact gattttattg
    21361 ccgaagttct taacccaaaa cttggagaat caatggcaga ccttgcttgc ggaacaggag
    21421 gcttcttgac ttcgactctg aaccgtttaa gtagtcaacg taaaaccagt gaagatacca
    21481 aaaaatataa tacagctgtt tttggtattg aaaagaaagc atttcctcat cttttagcag
    21541 ttacaaatct gtttcttcac gaaattgatg accctaaaat tgttcatgga aatactttgg
    21601 agaaaaatgt tcgtgaatat acggatgatg aaaaatttga cattattatg atgaatccac
    21661 cttttggagg gtcagaatta gaaacaataa aaaataactt tccagcagaa ttacggagtt
    21721 ctgaaacagc tgatttattt atggctgtca ttatgtatcg tttgaaagaa aatggtcgtg
    21781 ttggagttat tttacctgat ggttttctat ttggtgaagg tgtaaaaact cgcttgaaac
    21841 aaaaactggt agatgagttc aacttgcata cgattattag gttgcctcat agtgtctttg
    21901 caccgtatac aggaatccat acgaacattc ttttctttga taaaacaaag aaaacagaag
    21961 aaacttggtt ttatcgttta gatatgccag atggttataa aaatttctcg aaaactaagc
    22021 cgatgaagtc agaacacttc aatcctgttc gtgactggtg ggaaaatcgt gaagagattc
    22081 tggaaggtaa gttctacaaa tctaaatcat ttacacctag tgaattggct gagttgaatt
    22141 ataatttaga ccagtgtggc tttccaaaag aggaagagga aatcttaaat ccctttgagt
    22201 tgattcagaa ttatcaagcg gaaagagcaa ctttaaatca taagattgat aatgtattag
    22261 ctgatatttt gcagttgttg gaggacaaat aatgacacca gaacaactta aagcaagtat
    22321 tctccaaaga gcgatggaag ggaaattagt gccgcaaaat cccaatgacg aacctgcaag
    22381 tgaattatta aagagaatta aagctgaaaa agaaaaactt atcagtgaag gaaaaatcaa
    22441 acgagataaa aaggaaactg agatatttcg tggtgatgat gggaaacatt atgggaagtt
    22501 tgctgatgga agtactcaag aaattgatgt tccttatgat attcctgata cttgggagtg
    22561 ggtgaggttt tctacattgg ttgaaattgt cagaggtggc tctccacgac caatcaaaga
    22621 ttatcttact tctgaagtag atggaataaa ttggataaaa ataggtgata ctgaaaaggg
    22681 tgaaaagtat ataaataatg ttaaagaaaa aatcaaaaaa tcaggactta acaaaactag
    22741 atttgtaaaa aaaggtacat ttttgttaac taattctatg agttttggta gaccttatat
    22801 tttgaatgtt gatggtgcaa tacacgatgg atggttggct atttcgaact atgaaaactc
    22861 attaaataaa gattacctat tctatattct ttcatcaaat gtagtttatt ctcaatttct
    22921 atctctaatt agtggagctg ttgtgaaaaa cttgaatagt gataaagttg cttctattct
    22981 tatccctctc cccccactat ccgaacaaca acgcata
//
LOCUS       DAVHBD010000038        22877 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000038 DAVHBD010000000
VERSION     DAVHBD010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.038"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..154)
                     /locus_tag="VVK04_001558"
     CDS             complement(<1..154)
                     /locus_tag="VVK04_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU3990194.1"
                     /translation="MKSTKEEIQTIKTLLKDSRTAKYHKRLQIVIFRLMGKSYKEIIE
                     LLDCNQT"
     gene            complement(538..1734)
                     /gene="tuf"
                     /locus_tag="VVK04_001559"
     CDS             complement(538..1734)
                     /gene="tuf"
                     /locus_tag="VVK04_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU3990195.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2678..3547)
                     /locus_tag="VVK04_001560"
     CDS             complement(2678..3547)
                     /locus_tag="VVK04_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU3990196.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3770..4450)
                     /locus_tag="VVK04_001561"
     CDS             complement(3770..4450)
                     /locus_tag="VVK04_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU3990197.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4408..5514)
                     /locus_tag="VVK04_001562"
     CDS             complement(4408..5514)
                     /locus_tag="VVK04_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU3990198.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5625..5879)
                     /locus_tag="VVK04_001563"
     CDS             complement(5625..5879)
                     /locus_tag="VVK04_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990199.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(6219..6665)
                     /locus_tag="VVK04_001564"
     CDS             complement(6219..6665)
                     /locus_tag="VVK04_001564"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990200.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(6738..7063)
                     /locus_tag="VVK04_001565"
                     /pseudo
     CDS             complement(6738..7063)
                     /locus_tag="VVK04_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7297..9015
                     /locus_tag="VVK04_001566"
     CDS             7297..9015
                     /locus_tag="VVK04_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU3990201.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKTSGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9126..9473
                     /locus_tag="VVK04_001567"
     CDS             9126..9473
                     /locus_tag="VVK04_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU3990202.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9752..10588)
                     /locus_tag="VVK04_001568"
     CDS             complement(9752..10588)
                     /locus_tag="VVK04_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3990203.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10601..11230)
                     /locus_tag="VVK04_001569"
     CDS             complement(10601..11230)
                     /locus_tag="VVK04_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU3990204.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11240..11881)
                     /locus_tag="VVK04_001570"
     CDS             complement(11240..11881)
                     /locus_tag="VVK04_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU3990205.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12027..13256)
                     /locus_tag="VVK04_001571"
     CDS             complement(12027..13256)
                     /locus_tag="VVK04_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU3990206.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAISSEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13246..14412)
                     /locus_tag="VVK04_001572"
     CDS             complement(13246..14412)
                     /locus_tag="VVK04_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU3990207.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14556..15569
                     /locus_tag="VVK04_001573"
     CDS             14556..15569
                     /locus_tag="VVK04_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU3990208.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTNGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNEFHVPEAVCIR
                     FAP"
     gene            complement(15614..16033)
                     /locus_tag="VVK04_001574"
     CDS             complement(15614..16033)
                     /locus_tag="VVK04_001574"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU3990209.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16044..17450)
                     /gene="atpD"
                     /locus_tag="VVK04_001575"
     CDS             complement(16044..17450)
                     /gene="atpD"
                     /locus_tag="VVK04_001575"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU3990210.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17536..18414)
                     /locus_tag="VVK04_001576"
     CDS             complement(17536..18414)
                     /locus_tag="VVK04_001576"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU3990211.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18430..19935)
                     /locus_tag="VVK04_001577"
     CDS             complement(18430..19935)
                     /locus_tag="VVK04_001577"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU3990212.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19950..20486)
                     /locus_tag="VVK04_001578"
     CDS             complement(19950..20486)
                     /locus_tag="VVK04_001578"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU3990213.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20486..20980)
                     /gene="atpF"
                     /locus_tag="VVK04_001579"
     CDS             complement(20486..20980)
                     /gene="atpF"
                     /locus_tag="VVK04_001579"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU3990214.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20994..21710)
                     /gene="atpB"
                     /locus_tag="VVK04_001580"
     CDS             complement(20994..21710)
                     /gene="atpB"
                     /locus_tag="VVK04_001580"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU3990215.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21745..21945)
                     /locus_tag="VVK04_001581"
     CDS             complement(21745..21945)
                     /locus_tag="VVK04_001581"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU3990216.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(22020..>22877)
                     /locus_tag="VVK04_001582"
     CDS             complement(22020..>22877)
                     /locus_tag="VVK04_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU3990217.1"
                     /translation="GTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSVTKELKE
                     KILHYHNQKFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQAS
                     TNFKPAGQSIEQRFEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIP
                     NKSAEVVNQALKLILKQRKILSITADNGTEFNRLFDVFSEEHIYYAHPYAFWERGTNE
                     NHNRFIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKM
                     EIIFIKRFQ"
BASE COUNT         6768 a         4896 c         4194 g         7019 t
ORIGIN      
        1 ttgtttgatt acagtctaaa agctctataa tctctttata agatttgccc atcagacgaa
       61 atataacgat ttgaaggcgt ttatgatatt tagctgtacg agagtctttt aaaagtgttt
      121 tgatggtttg gatttcttct ttagttgatt tcatattact attgtataat gctttttgat
      181 ttgagtctag tattatactc ttcgaaaatc tcttcaaacc gcgtcagctt cgccttgtcg
      241 tatagatgtt actgacttcg tcagttctat ctacaaccta aaaacagtgt tttgagcagt
      301 ctgcagctaa ctttctataa caaaatgaaa taagaacaag acaaatcaat caagacaatc
      361 aaatcgattt ctaacaatgt tttagaagta gatgtgtact attctagttt caatatatta
      421 tagtttgctc tttgattttc attgagtatt agttcaatat ctaaaaaaag aaccttgcca
      481 agcaagattc ttttagtgtc taacttaaat aattgttctt ctgggaacta aatcgaatta
      541 agcttcgatt tctgtaacca tacctgaacc aacagtacgt ccaccctcac ggatagagaa
      601 tgtagtacct tgttctacgg cgattgggtg aatcaactca acgtcgattg tcacgttatc
      661 accaggcatt accatttcag tacctgctgg aagttcgatt gaacctgtaa cgtcagtagt
      721 acggaagtag aattgtggac ggtagttgtt gaagaatgga gtgtgacgtc caccttcttc
      781 tttagtaagg atgtagactt cacctttgaa tttagtgtgt gggttgattg aacctggttt
      841 agcgataact tgtccacgtt cgatttcatc acgttgaaca ccacgaagaa ggacacctac
      901 gttatctcca gcaagacctt cgtcaagttg tttacggaac atttcaacac cagtaacaac
      961 tgctttttga gtttcttctt tgataccaac gatttcgatt tcgtcgttga ctttaacgat
     1021 accacggtcg atacgtcctg aagcaactgt accacgtcca gtaattgaga atacgtcctc
     1081 gactggaaga agcaatggtt tgtcagtgtc acgttctggt tctgggatat actcatcaac
     1141 tgtgttcatc aattccataa cgatgtcttc gtatttagag tcaccttcaa gagctttaag
     1201 tgctgaacct tggataactg gaagatcgtc acctgggaag tcgtattctg acaataggtc
     1261 acggatttcc atttcaacca attcaagcaa ttcttcgtcg tcaaccaagt caactttgtt
     1321 catgaagacg ataaggtgtt taacaccaac ctgacgtgaa agaaggatgt gctcacgagt
     1381 ttgtggcatt ggtccgtcag ttgaagctac tacaaggata gctccgtcca tttgagcagc
     1441 accagtgatc atgtttttaa cgtagtccgc gtgtcctgga gcgtcgatgt gagcgtagtg
     1501 acgtttttca gtttcgtact caacgtgcgc agtgttgata gtgataccgc gttcgcgttc
     1561 ttctggagca gcatcgatag acgcatagtc tttaggttgg ttaactgatg aaggcaagcg
     1621 acgtgccaaa acagttgtga tagctgcagt tagggtagtt ttaccgtggt caacgtgtcc
     1681 gatagtacca atgttaacgt gtggtttact acgatcgtat ttttcttttg ccatttgagt
     1741 aaaagcctcc aataaaatat attttataga tagacagtag gcaatacagt ctaactttcc
     1801 ttactatttt atcaaatttc agctaaattg caagtgtttt acaacgtttt tgtgaattat
     1861 tcttggtaaa aatttaacta attaatagaa agtactaaat agacttatcc ttcaaggagt
     1921 tttcagcatt atccatccac tcacttgctg aaaatgtaaa cagtctctgg tttatatagt
     1981 aaaatgaaac aagaataggg caaatcgatc aggacaatca aatcgatttc taacaatgtt
     2041 ttagaagttg aggtgtacta ttctagtttc aatctactat acaacctcaa aactgtgttt
     2101 tgaacaacct gcggctagct tcttagtttg ccctttgatt ttcattgagt ataaaattgc
     2161 agataaaacg ataacaatca taggactcag cagagtcaat gtaggtcgaa gaatagcccc
     2221 cctaatcgct tattttatag caaaatgaaa tagaaactga acattttgtt gaggaaggta
     2281 aatcaattcc tcacaatgtt tgagaaagaa gggaggacta ttccaacttc aacccactat
     2341 aaagcagact tacaagatag ggaacccatc tccgataata ttccgataat atatagtaga
     2401 atgaaaactg cacaatttga ttggagaatt caaaccaatt tctcacaatg ttttagaaac
     2461 aagggtctat tatttcaact gcaacctact atagtccatt gaagctggaa tagcccactg
     2521 agacttctaa accactgctg gagaggagtt tgtttagagt ttgtttagag tttgtttaga
     2581 gtttctttca tttccctaaa aaatcaaaaa gagagaacca gtctgatcct ctcttactta
     2641 tagatggtgc tcactcaaat gttaaaggag ctatttctta gagataaagg aatttgaata
     2701 cagctactgc cgcaattgct gctgcaatag gtgctactac tggtacccaa gaataccacc
     2761 attttgaatc gcctttatgc tcaccaagaa ctgattttgg aaggaaagca tgaaggagac
     2821 gtggtcccaa gtcacgggct gggttcaagg caggtcctgt aggtcctcca agtgatgtta
     2881 ccaaagccat aacgaggaat ccaagtgcca agtgagccac agaaagtcct gaagcagtgt
     2941 gtggagccac ctgtgcttta atagccaagt cagaaaaatc aactgtttgt cctgcttcta
     3001 ttgccttttg tttcatgaat tgaagcactt cagcaccaaa gaagttttta gtcaaaccaa
     3061 gagctgcaaa gaacaaaaca aatgaaccaa caaactcatt aatcaaacca ttgacagttg
     3121 ctgcatagcg actttctttt gtaccatggt caatacttga aatagttgag aaagttccca
     3181 agatgttatt tgggttttca gttttcaagt agaatggacg gtatgttgcc acaactaagg
     3241 cttggccaaa gatagccccc aagacttgcg cgataatata aggtaccact tgtgcccaag
     3301 ggaaaagacc gctaactgca agccctagag tgaaagcagg gttgatgtga ttcccagata
     3361 cgttaccaaa catcaaggct gggatcataa cccccatacc ataaccaaca gcgatgacga
     3421 tccagccact ttggtgacct ttcgtacctt taagttcaac gttggcaact gcaccattcc
     3481 caagaatgat caaaatggca gttcccaaaa attcagtggc atacttcagt gcccatgtga
     3541 aatccatttg ctagattctc cttaaaattt tttagatatt ccttatttta tcaattttta
     3601 ccctatttag caactgattt ctggaaatat ttttaaaaaa ataggattca tagtttccca
     3661 gttcaacgta cttgtaagcg tttttattct tcacaaaaga cctcattctc aaaaccagga
     3721 aaaagcccac atctgtgatc ttttccttgt tcctagattc taaaatctat tatttttcat
     3781 cttctttttt cttgaagaat cctaatccta gaccagctaa caaggtcatg ataccagcac
     3841 tagccaaggt agcattagct tctgtacctg tgtttggcaa ttcctctctc ttacctgtct
     3901 cataagtcgg aacttctggg tctggattca ctggagtttc agtttttgga gtacctggtt
     3961 ctggagttgg tttatctggt gttggagtct cttgatttgg tagttctggg tttggtgtcg
     4021 gaacacttgg atgctctgga tttggttgtg ggattggttt ttctggagtc ggttcacctg
     4081 gagtacctgg ttcctgagga cttggaattt ctggtttttc tggagttggt ttatctggtg
     4141 ttgataaacg gtcatacctt accgttattt ctttatcact agagtctgac gtaacttctt
     4201 gtgattcaac tgttggaata tctggatctt tgtacttgtc aatcttacca gatataacct
     4261 cgtcccagtt tcctgttgtc cattcaccgt aggttacaac tcccgtgacc ttgttctcag
     4321 tttttgtacg gcttaaggtt acaggttgaa caacatcttc ttttacattt tggttcgtaa
     4381 ctttatcaac gtaatgaatg atacgcgtta tagtcttcgt ctcagtagag gttgctgttt
     4441 tgggaaccac tgtttcctca acattctcac ggtagtaata gtcaactgtt gcaccgtctt
     4501 ctggtacgca tttgcaggag ttgctaccaa ggtgtatgtt gttttccttg tgataactcg
     4561 gtcttctttg tcctcagttg ttgttttccc ttcaatagtt tttgattctg tggtatactc
     4621 agagcctatc gctaaatcag cttttataac agactctgcc aacttctctt ggctaccttc
     4681 tttatagtaa ttggctgtta ctgtagcagt ggttggcgct tcgctttctc tataaactaa
     4741 ggtcactgtt ctaccttcgc ttacaatatt cccagttaaa cttgcagaat ttgtatctgc
     4801 ttctttaaaa gtataatatt ttccgtcagt agtagtcatg ctactgagtt ttttatctgt
     4861 gacattgtag ctggtaccaa tcagttgttt tttattggta atgtaggttc cgtcactttc
     4921 tttttctcca attccagtat catttttcaa tgatagcaaa cgcccttgtt catcaacata
     4981 gcgaactttc acattttctg agattagttc tgccaattct gaggtttttt tctttttctt
     5041 gatttcttcg gttattttcc ctttctcttc ttcgggaata tttagttttg gaatgatttt
     5101 ttcaacaacg gttcgtgatg gttccacagt atcttggatg actgaaaagt cagctagaat
     5161 tgggagatta tactgaacac ggtgactttg agtgtttact cctactcttt cattattctc
     5221 tgaaaatact tgtacggtat aagaaacaac atcttttcct aatagaacat ccccagtaga
     5281 gaaatagccg ccttttccta gtttgctatc tccagagccc acttctttcc taatcttatc
     5341 agatagtttt ttaccagtca gtacattcgt tcgcacaatc cctttgtcta cccctacaaa
     5401 gtgggagaac tttttgaact cttcagaacc agatctagcc caaccattat taagggcatt
     5461 tgcttttgta tttgtattct ctctcaaaag tttggcgatt agaattatat tcatcggcac
     5521 ttagagttgc tgctatatct gactcttgaa taccaacttc cttactacca tttctagcgg
     5581 cagtatatgt gtatttatct gtttctactt ctagctgatt atccttaaca tgataggtaa
     5641 ttttctcctg gtataagagt cttcagtagt ttatatgctc tgtcatcatc tttagcttta
     5701 gaagcagctg agtttagcca agttggggta ttaggagtat ctttatcagc ctgtttcaag
     5761 acattattca agtcatttgc tagcctattg gttgtcctca ctgtgaaagt tttcttccag
     5821 tctgaaccac ttttattaga cttagatatg ctcatgaaat cctggtcaac attcaacaca
     5881 atatcgcctt gttttttagc atcttccgtt gcttctgctt caaattgatc atggagtttt
     5941 tgttgctctg gtgtatagtt tttttattta cacgatttaa tgtactattt tttattttag
     6001 tattaagaac tccattaata cgatttttaa actctgcttc aaaaaatccc ttaatttgtt
     6061 ggtgcgcaag ttcaacattc aaaccttttt tatacaagtc ttcattctga acgatttcgg
     6121 ctacacggtg aatggtttga ttgtataccg tcttctctta accagcagta tccttagttt
     6181 taatgactac tcgataggtt cctttagaac cgttatagtc atctagtttt aaaaaagcat
     6241 tccaaacatt caaaaatagt tggaacttcc cttaataaat ccgtcacttt ctttttcaag
     6301 atagcccaag cttgctcaat aggattcaaa tccggtgaat aaggtggtag aggtaagaaa
     6361 aagtgtttat cttggatgca gagttcatcc aaaatgttct tgggatgaaa accagcattg
     6421 cccatgacaa taacatgagg tgtcttcaaa gcaggtagga gttgcgtttt gaaccactcc
     6481 acaaagaaat cgcttgtcat gcttttcttg taaatcatgg gagctataaa ctctccgtct
     6541 acttgtcctg caacaattga agttcgctca aaacgacgtc cgctaatctt ttcatagact
     6601 ttctcccctc taggagcccc tgcataagga cgatagagat agcggtcgat tcctgtttca
     6661 tcaatataaa caggtgctag gtgctttaaa ctattaaaat tcttaagaaa taaggctact
     6721 tttctgggtc ttgttcctta aagctcgtca tcttttttta aagtgacctt aatctgcttt
     6781 aaagctgccc atactgaagg aacagcacaa tcaaaatgtg ccgcaatttc ccgtaaaaaa
     6841 gcatctggat gagcctctac aaaggctttc aattcctcta aaggaatctt tcggtttttg
     6901 acgactcgct ttttcctctc tatgtgttct tgttcacgtc tttcttttcc cacgtgaaga
     6961 gagttctgac gccaacacca aaaaacttgg ctgcctcgac atggctgtgc ccctctttga
     7021 tgtaatctaa tgctcgctgt ttaaaatcag tactatatgc catagcttta ttataatatg
     7081 cttgtttaaa actaagtaac tatatcaatg ttttgttatg agaagactta ctttttttac
     7141 tgaaattgaa tttttcctag cctcaacatc atataacccc aaaattcaat ctgacctggt
     7201 ttgaagagat tttcgaagca gataaggttt tactaaaact aaaaaaaatg atataatcaa
     7261 actgattaaa tgttttaaaa ataaaggaga atttgaatgt cttaccaaga aaattaccag
     7321 aaatgggttg attttgtgga gcttcctgac taccttcgtc aagatttgga aaatatggac
     7381 gaaaaaacta aggaagatgc cttctataca aatcttgaat ttggtactgc aggtatgcgt
     7441 ggcttggttg gtgctggtac aaaccgtatc aacatctacg ttgttcgcca agctactgaa
     7501 ggattggctc gtttgattga gtcaaaaggt ggaaacgaga aagaacgcgg tgtagcaatt
     7561 gcctacgata gccgtcactt ctcacctgag tttgcctttg aatctgcggc agttcttgct
     7621 aaacacggca tcaaatctta cgtatttgaa agccttcgtc cgactccaga actatcattt
     7681 gcagttcgtc atctcaactg tttcgcaggt atcatggtca cagccagcca caaccctgct
     7741 ccatttaacg gttacaaggt ttacggtgaa gacggtggac aaatgcctcc acacgatgcg
     7801 gacgctttga ctacttatat ccgtgcaatc gaaaacccat ttgcagttga agttgctgat
     7861 gtggaaactg aaaaaacttc tggcttgatt gaagttatcg gcgaagctgt tgacatagaa
     7921 taccttaaag aggttaagga cataaacatc aacccagcct tgattgaaga atttggtaaa
     7981 gacatgaaga ttgtctacac accacttcat ggtactggtg aaatgttggc tcgtcgtgct
     8041 cttgcccaag caggatttga ctctgttcaa gttgttgaag cgcaagcaac tgctgaccca
     8101 gacttctcaa ctgtaacatc tccaaaccca gaaagccaag cagcctttgc ccttgctgaa
     8161 gaacttggtc gtcaagttgg tgcagatgtt cttgtcgcaa ctgacccaga cgctgaccgt
     8221 gttggtgttg aagttcttca aaaagatggt agctacctca acctttcagg taaccaaatc
     8281 ggtgctatca tggctaaata catcttggaa gctcacaaaa acgctggaac tcttcctgaa
     8341 aatgccgctc tctgcaaatc tatcgtttca actgacttgg taacgaagat tgctgaaagc
     8401 tacggcgcaa ctatgttcaa cgtcttgaca ggtttcaaat ttatcgctga aaaaatccaa
     8461 gaattcgaag aaaaacacaa ccacacttac atgatgggat ttgaagaaag cttcggttac
     8521 ttgattaaac catttgtacg tgataaagat gccatccaag ccgttcttgt cgttgctgaa
     8581 cttgctgcct actaccgttc tcgtggtttg acacttgctg acggtatcga agaaatctat
     8641 aaagaatatg gctactacgc agaaaaaaca atctctgtta ctctttcagg tgtcgatggt
     8701 gctgaacaaa tcaaagcgat tatggctaaa ttccgcaaca atgctccaac agaatggaac
     8761 gcaacagcta tcactgtcgt agaagacttc aaggcacaaa ctgctactgt tgctgacggt
     8821 actgttacaa acttgacaac tcctccaagt gatgtgttga aatacacact tgctgacggt
     8881 tcatggattg ccgttcgccc ttcaggtaca gaaccaaaaa tcaagttcta cattgcagtt
     8941 gtaggggaaa ccaacgaaga atcacaagct aagattgcta acatcgaagc agaaatcaat
     9001 gcatttgtaa aataaagacc tataaaagat gagaccaacc aacctcatct tttttcgtat
     9061 caaatctaag caattttaga aactttatgg catactagac ttatcaatga aagcgaggta
     9121 atctcatgga acaattttta gataacatca aagaccttga agtcactaca gttgtgcgtg
     9181 cgcaagaagc tcttgataaa aaagaaactg caaccttctt tatcggtcgc aaaacttgcc
     9241 cttactgccg taaatttgca ggtacattgt caggtgtcgt agctgaaacc aaagctcaca
     9301 tttacttcat caatagtgaa gaaccaagcc aactcaatga tttgcaagca ttccgctcac
     9361 gctatggaat cccaactgta ccaggtttta ttcatattac agatggacaa atcaacgtcc
     9421 gttgcgactc ttcaatgtca gcacaagaaa tcaaagattt cgcaggattg taaaaaatca
     9481 gctaacaagt cttaaaatca caaaaacgca taatgtaagg tgcaaaaacc ttgatattat
     9541 gcgttttatt gttcctaaaa cagttacatc agcatttcat tacagaacat tttaattttg
     9601 gaagtcaaat caatttttaa caatgtttta gaaatcacag tgggctattc catattcaat
     9661 tatccagatt caatcgctat tatcgttttc ctagattaca aaaaaaacta cgttttgcta
     9721 atcaaaacgt agtctcagcc actattttat cttactgtcc ttcttttact tctttggttg
     9781 ctacatcttc tccaaaccat ttttggctga tttcttggaa cttgccgtcc ttgtaaagac
     9841 tagaaaaagc ttcatttatc ttcttaacca aggttgtatc ttccttacgg gctccaaccg
     9901 caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa acaccttctg
     9961 cttctaaata atagtttgca tagacacggt caatcaatag accatcaatt cgatcgtttt
    10021 tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa
    10081 tattcttcaa aagttctgga tttgcttcaa agtccgcata accagatgaa ccagcttgag
    10141 ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat ttcttcgtaa
    10201 ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca cggcgttcgt
    10261 ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat tcagcttctt
    10321 tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca aaaacagctg
    10381 tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat cccattggaa
    10441 caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt gaccaattat
    10501 ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca gtcatcagac
    10561 tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt tctactttca
    10621 ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca atctgggtca
    10681 tcccaagttc cctattttgc aagattagct tctccacttc caaacgtaat tctggatcca
    10741 gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata gcacgcgcca
    10801 aagccactcg ctgcttttgc ccaccagata gtgagaaagg ataggcctct gcgtgtcctc
    10861 ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc tgcttcattc
    10921 ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga ggaaatagtt
    10981 gaaaatcttg gaagacaaat cccagtaggt tgcgcttctg caattcatcc agctctaaag
    11041 gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacctgca agcatacgta
    11101 aaagagttgt cttacctcca ccagaaggtc caacgatagc caggatttgc ttttcaggaa
    11161 tacttagact gaaattagac aggatttgtt tgtctccaaa gactttattg atatttcgta
    11221 attctaacat ggcagcctcc tatctataat aactatactt cttctcaact tttttggaaa
    11281 taattgtcac aatcccaatc aaaatcaaat aaatggctcc tgccaagaac ataggaacta
    11341 gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa attccgagag
    11401 catagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca ctaggaagaa
    11461 caatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg ctaaacttta
    11521 agaccttggc agcctcatac tgtcctcttg gaatagtgtc aattccccca cggaaaattt
    11581 ctgcaaagta agctgcatag ttgagaacaa aggcaataat agctgcagga aggcggtcta
    11641 aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag agtaaggggg
    11701 ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc caatggactt
    11761 gcaaggcaaa ggcaatcaaa acgcccaagg gaatcgaaaa tagcaagacc agtgcaaaga
    11821 cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat aaataagaca
    11881 tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag attaccaagt
    11941 atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa aagagataaa
    12001 ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg catttgcaca
    12061 tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc
    12121 aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt caaatctcct
    12181 gtcaactctt gataatgctc ataagcagta tccaaatcgt ccatttcttg ataagaacga
    12241 gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaagtc tagaatatcc
    12301 tcataacgct cctgctccag ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc
    12361 tcagcgtctt cttttgcagt aaggagataa ttttctgcac cactagcatc atgcaattca
    12421 taagaaaatt gtgaagcagc tagcaagagg cgagtttcaa agggattttt ctctaatcct
    12481 tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc ctgactgtac
    12541 ccatactcat agccttcaaa gtcaggagaa atggtatcaa gctgcttaaa gtagagggtg
    12601 gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc tgttaagtca
    12661 tcgtattcta actccagggc tttttctaaa aactcagtag ccgtttcaaa tttccctaac
    12721 tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag
    12781 cgattatcta actgggcata ggcttgaata gccgcttggt aattttccaa ctcactatcc
    12841 aactctgcca aacccaatat caagagagaa tcctctgagt aggtcaaggc ctccaataat
    12901 ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt caaaaccaaa
    12961 gacgagacat accagtcact gtcagcttgg atttcctcaa gataggtaaa ggcttcttct
    13021 atttgaccat cctcgctaga aattgcagct agattaagat gaacctctgg aaaatcctct
    13081 acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc aagataagtt
    13141 gccaactcat acagaagatc acttgaatca ttttctaaag ctttggcgaa ataatgctca
    13201 gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt gttcactctt
    13261 gacttcctca ccctctaatt catatagacc actgactacc ttataccatt cgaaaatggc
    13321 tgaaatgaca accttagcag aggcataaac cggaatacca agtaaaactc cccagatacc
    13381 aaacatagat cctgaagtta acaaaacaaa gagaacatta atagggtgga tgtttaattg
    13441 acttcccaaa atcaatggag agacaaaacg gccttcaata gtttgttcta caataaagac
    13501 aatcactact ttcaaaagca tgactggacc agcaatcaaa cccaatacta gggcaggaag
    13561 catggctaga aagctaccaa gataagggac cagatttaaa ataccagcag taacccccag
    13621 cgtaaccgca tagcgtagac caataatctt gaagaagatg ataaacatta ctgctacaat
    13681 aatagccact gtcacttgcc ctcgaacata gttggacaac tgttgattca catctgatag
    13741 aacttgtcca acaggttcct tcaattttct tggaatgaat tgggtcaaat agttacgcaa
    13801 gcctttccca tcacgcaaga gataaaagag catgaaagga acgataatca aggcaacaat
    13861 cacttgagaa gccccgctaa taaaggcact cacccagttg actgcctgag atgaaacctt
    13921 acttgccaaa actgtagcct ggctagaaaa attggtcaaa acttgctcta attgaggtct
    13981 gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta tatcttctaa
    14041 gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg gaatggcgac
    14101 tgccaagccc caaatgataa agagagcgat gataacaaag acaatagtga tagctataac
    14161 acgattaacc ttatgcttct ccatccaatc aacaatagga ttcaacaaat aatataacaa
    14221 accagacaaa atgactggca acatcacaac tgctaaaaag tctaaaacag gtgaaaatag
    14281 aaaactaatc ttacttaaaa taaaaagatt cagtcccaat aataaggtta ctaaaaatac
    14341 cgtaattgcc ttgttatcta aaaaccactt gaaaaaccaa gataggctaa aatgtttctc
    14401 tttttgctcc ataaatactt cctttctatt gttctctcat tataccattt ttgaaacaaa
    14461 ataactcttt tttaaagtgc ttacatctaa ttggatgtct ttaatttgct tgtttttgtg
    14521 atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt tattttggaa
    14581 cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca gaaactggtc
    14641 agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt gcctttgacc
    14701 agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt gcagcctatc
    14761 aaactaacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac tgttatgttg
    14821 ctgtcgatga aaagcgtgat ttggtttacg cagccaacta tcacaaggga caagtccttg
    14881 tttataaacg ccaggaagat ggtagtcttc tacttagtga tatggatcaa cacagtggcc
    14941 aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta acacctgacc
    15001 actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac ctcgatcaag
    15061 aaggaaaatt atctaagctc tatacctatc acagcaagcc aggagcaggc tcacgccata
    15121 tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat agtactatcg
    15181 aagttttaat ctacgatggc gttggcgaat ttgtacgtat gcaggttatt tcaactttac
    15241 cagaagctta cgaaggcttt aatggaaccg ctgctattca tctctctaaa gacggtaaat
    15301 acctctacgc ttctaaccgt ggccatgatt ctatcgcagt atataccatc cttgcggacg
    15361 gtagcttaga gttattagaa atcgttccaa cgcatggtca gactccacgt gattttgatt
    15421 tgacacccga ccaaaaattt ctcattgttg tccatcaaga ctctgacaat gcaactgtct
    15481 ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgaattc catgttcccg
    15541 aagcagtctg catccgtttt gctccttaaa acaccataaa aaatgaactt ggtattttca
    15601 agttcatttt ttcttatagt ctatttccga cattaatacg gttaatggca cgttgcaaag
    15661 caatcttagc acgacgttct tggtcaatca aatgtttgtc ttgtgcttct tcaattgcac
    15721 gttctgcacg aagtttggca cgttctgcac ggctaatatc gatatcacga gcacgttctg
    15781 cagagtcagc gacgattgtg atcatatcat tggcaatttc aataacgcca ccgtttactg
    15841 caatccagtt cacgtgatct ttatcatcga tacgttttac ctttacttca tcaactgcta
    15901 aaaccgcaat catattttca tgtcgtggca agatccccat ctcaccatcc agagttcgaa
    15961 ccgatacata gctggcatgg tgatcataga cgagaccatc tggtgtcacg atctggacag
    16021 ttaactgagc cataggtcac ctcttaaaat cccatttttt cagcttttgc aatcacatct
    16081 tcgatagaac ctacaccacg gaaggcatct tctggcaagt ggtcgtattt accatcaagg
    16141 atttccttaa agccacgtac agtttcagca actggaacat aagaacctgg ctgaccagta
    16201 aattgttccg caacgttgaa gttttgtgac aagaagaact ggatacgacg ggcgcgagca
    16261 accaaggtct tttcttcatc agaaagctca tccataccaa ggatagcaat gatatcttgc
    16321 aattcatggt aacgttgaag gacacgtttt acttcagcag caactgcata gtgctcttct
    16381 ccaacgattt caggtgccaa ggcacgtgag cttgaagcaa gtgggtcaac ggctgggtag
    16441 atacccaatt gtaccaactt acgttccaag tttgttgttg aatccaagtg agcgaaggct
    16501 gttgctggcg ctgggtcagt atagtcatcc gctggcacat agatagcctg gatagaggtt
    16561 acagaaccct tcttggttga tgtgatacgt tcttgcaatt gacccatttc cgtagcaagt
    16621 gttggttggt aaccaacggc tgatggcata cgacccaaaa gggcagatac ttctgaacca
    16681 gcctgagtga aacggaagat attatcgata aagagaagca cgtcttggcc ttccacatca
    16741 cggaagtatt cagcgattgt caaaccagta agggcaacac gcatacgtgc tcctggtggc
    16801 tcattcatct gaccaaagac catggctgtt ttctcgataa cgcctgattc tttcatttcc
    16861 cagtaaaggt cattcccctc acgagtacgt tccccaacac cagtaaatac tgaaatacca
    16921 ccgtgctctt gggcaatgtt gtgaatcaat tcttggatta agacggtttt accaactccg
    16981 gcaccaccga aaagtccaac tttaccacct ttaaggtaag gggcaagaag gtcaataacc
    17041 ttgatccctg tttcaaggat ttcagaagag gtagacaact catcaaaagt tggagctttt
    17101 ttatgaattg gctgacgctc tgcgtcttct gtaaaaggag cttccaaatc aatggtatct
    17161 cccaaaacgt tgaagacacg tcccaaagtt tctttaccta ctggtacaga gattggacga
    17221 cctgtgtcca atacttccat tccacgagtc aacccatctg ttgattccat ggcgatagta
    17281 cgaaccatac catctcctaa ctccaaggct acttcaagga cgatttttgt ttttctttcg
    17341 tcatttttgt agacgacaag tgcattgtta atctcaggaa gtttttcccc tgctgcaaac
    17401 aaaacgtcta caacgggacc gataacctga gcaattttac ctgaactcat ctccttctcc
    17461 tattctatat aagatactgt cggttcctag ctcaactagg tcctaagttc attttcatac
    17521 gagctggact agagcctatt ctaaggcact agcacctgct acgatttctg taatttcttg
    17581 tgtaatcgcc gcctgtctgg cacggttata ctgaattgtc aaatcattga tgactttctt
    17641 agcattatct gtcgctgttt gcatggctgt catacccgca gcattctcag ctgtcttggc
    17701 atcgataatg gcaccgtaaa tcatactttc tgcaaactga ggcaacaact gctccagaat
    17761 ttcttctcgg ctggtttcca attcaaaagt caagctgtac tcttcatccg cttcatttgg
    17821 atccaagtca acaatcggaa gcatttgttc cacacgcatt tgactggtta gcgtattgac
    17881 atggtggttg tagcaaacat aaagctcatc aaagagttca ttttggtaca tttcaacagt
    17941 ttttgaaata atcttacgaa cttgatcaaa gctaggttgg tctgccaagc cacgtaattc
    18001 ataaagtggt tgaataccgc gagccttaaa gaaatcagct cccatcccac cgatacagat
    18061 catttcaaaa cctttaccgt ctgggtggta ttcttctttc aactccataa cagctttcaa
    18121 aatagaggaa ttataacctc caaccaaacc gcggtctgaa gtgataacga tatagcctgt
    18181 cttcttcaca gaacggctaa tcaacatcgg attagttgaa gcaccagctc cattaccatg
    18241 aaggatatct gtcaaaagtt tacgcacttt ctgagcgtaa acttggaagt tgcgagcagc
    18301 ttcttcagaa cgacctagct tagcagccga taccatttgc atggcattag tgatttgact
    18361 cgtatttttt gttgaggcga tttttgtttt aatatcattt agagatactg ccatctgaca
    18421 cctctattct tattggaagc tagattgatt gagaaactct gtaatcgcag catccaagac
    18481 tgcttcttct ggcaagtctt ttgtatcacg aatggtttcc aaaatctctg gatgttgagc
    18541 atcaaagaag gcatggaact cttcctcgaa acgaacaata tcatctactg gaacagtatc
    18601 caagaaacca tgtgtcaaag cataaagaat ggttacttgt ttctcaacag gtaatggttt
    18661 gtgaacaggt tgtttcaaga cctcaacggt acgacgtcca cggttcaact tagcctgtgt
    18721 tgctgcgtcc aagtcagaac caaacttagt aaaggcttcc aactcacggt atgaagcaag
    18781 gtcgatacga agtgtaccag caaccttctt catggctttg atttgtgcag aaccacctac
    18841 acgagataca gatgaacccg catcgatggc tggacgaata cctgcattga agaggccatc
    18901 gccaaggaag atttgtccat cagtgataga aatcacgttg gttgcgatat aggctgagat
    18961 atctcctgct tgtgtctcga taaatggtag ggctgtaatt gatccaccac caagttcatc
    19021 agaaacttta gctgagcgct caagcaaacg gctgtggaga tagaaaacat cccctgggaa
    19081 ggcttcacga cctggaggac gacgaagcaa gagcgacagt tcacgataag ctaccgcttg
    19141 ttttgataga tcatcgtata caatcaaaac atgcttacct tgatacataa attcttccgc
    19201 catagcgacc ccagtataag gagctaggaa gagcaatgga gatggttgtg aagcagaggc
    19261 tgtcacaacg attgtgtagt ccaaggcacc gtactgacga agtgtttcta cttgcgtacg
    19321 aactgttgat tctttttgtc caatcgcgac gtagatacag atcatatctt gatctttttg
    19381 gttcaagatt gtatcaatcg caatggttgt tttccctgtc tgacggtcac cgataatcaa
    19441 ctcacgttga ccacgaccaa tcggtacaag ggcgtcaata gctttcaaac cagtttgcaa
    19501 tggttctgaa acagacttac gttgcataac accaggagct ggtgcttcta ctggacgagt
    19561 tttatcagtg tggatttctc caagaccgtc aactggacga ccaagcggat ccacaacacg
    19621 accaatcaga ctttcaccta cagggacttc catgattttc cctgtacggc ggattgtatc
    19681 gccttcacgg atatctgtaa agtcacctag gatgataata ccaacgtctg ttgactccaa
    19741 gttttgagcc ataccataag agccgttttc aaaattcaac aactctccac tcatgacatt
    19801 ttcaaggccg tgagcacgcg cgataccgtc cccgatatag gttacaacac ctgtttcagt
    19861 cacatcaaaa ttgggtttga aattttcaat ttgttgctta attaaagcgc tgatttcttg
    19921 tgcgttaatt gccaaaagaa caccactttc tatttcaaat tttctttaac aactttaagt
    19981 tgttgtttaa tactcacatc aattgtcttg tgattggcaa aaatgacaaa accaccaatg
    20041 agactttcat cgatttgttc ttttacactc cttactttca gagacatttt tttctcaatc
    20101 aaagggagca aacgagtctt ctgttcatca gttagaggat gagcagacgt aatcgtcact
    20161 tcaaatcgat ttgtttcttt ttcaagtcgg ttcaagcaat ctacaagcac atcataaaaa
    20221 agatttgctc tgtgattgta ggccagaacc tggataaagt tttgtaataa aggtgacaca
    20281 gaatcttgga aaaaagcaat tgttttttcc ttatccgact cgtctactgc cacttgtttt
    20341 aaaaaagaag gcagacctgt tttttcaaca acttgcttga tttgagtcaa gtctgaaaag
    20401 atacggtctt cttctccttt ttcaagtacc aattggacaa aaggcatgct gtatttttca
    20461 attaccttta ctgttttctt gtccattaag cttctcctag ctgatcgata tactgatcaa
    20521 tgagtgcttt atgggcatga ctgtcaaggt tttgtgagat gattttacca gctaagctga
    20581 tggtcaaatc tgcgacctca cccttaacac tctgtaaagc ttctacttta ttttgagcaa
    20641 tttcttgatt ggctttttct tttaagtgtc ctgcttctag tttagcatct gctaagatat
    20701 tagccttact ttgctcagct gtttcctttg cattttcaat gattgtctta gcttctttac
    20761 ggctaccagc caattcatct tcgcgttttt gagccaatac ttctgctttt tgacgggctt
    20821 cttcagctct gtcaatatct gaagcaattt tttcagctct ttcttcgaaa atgcctgtaa
    20881 tattagacca tgcaaatttt ttaatcaaga ctagcaaaag aataaaagag ccagtgatta
    20941 aaataaaatt accaattaat tcacctactg ttacgtgcat cagttactcc tttctattcc
    21001 tcttcaatat taatcttatt ccctaaatac acagatgtca aaagagtaaa aacataagct
    21061 tggatgcagg aaataaagac agaaaatgca gtccaagcca aattagctcc aaaggctact
    21121 ggataccaat aaatagcttg gtgggaaaga agaagtaaca aactcgtcat gacctctcct
    21181 gcaaagatat tcccaaaaat ccgcaaagcc aaagataaga agtttgtaaa ttcttccaag
    21241 atattcatcg gtatgacaaa aacaggactc ataaaagatt ttatactttt tttaaatcca
    21301 cgacgacgaa cgctttctat atgtgtcaac aaaatgacaa gaaaagataa ggttaagtca
    21361 tactgtaaat tagcggttgg cgaactccac cagttagtcc catcgatcgt ttgaagcttt
    21421 gtcattaagc caaggttatt ggcaatcacc atgaaaagga ataaacaaag gaaaaagagt
    21481 gagtaatctt tcatgtagcg cgaaccaatg ttaggttctg taaatccaat aacaaagtca
    21541 tagacatact caagtacatt ttgctttcct ttgggtttca aggtcatatt gcggcttgcc
    21601 caataaataa agacaaaaat aactcccaca atcaacaaag tcatggctaa catagtcaga
    21661 ttgaagataa caggaccaat agagatgatt ggattaatac tttcttccat ctaaaatcct
    21721 cccttttctt ctcgttccat gtatttattt gataataaat gagaagacaa gagttacaaa
    21781 gaaagttcct tcaataaagg caacacctaa aaacatcaaa ctacgaaatt cagaaagcat
    21841 atctggttgg cgtgctactg atttaaacag tccattcatc aataaacctt caccgacaga
    21901 tacgcccata caggcaatac ataagcctaa aaatgttaaa ttcataacaa attctccttt
    21961 aaaataaaat ttacttactt agtgtagtcc taaaatttaa atttgtcaac ttttaaccgc
    22021 tattggaagc gtttaataaa aattatttcc attttgctaa atttcaagtt caagttagcc
    22081 atccagaagt cttctctggg tgacttgtag tccaagcatt ttttaggata gttgttaatc
    22141 cacttttcga tgaatgcgac ttctttggga gtcattttct tggttccctt aggtaaccat
    22201 ctacgaatga acctgttgtg attctcatta gttccccttt cccaaaaggc ataggggtgc
    22261 gcataataaa tgtgctcctc agaaaataca tcaaacaagc gattgaattc cgttccatta
    22321 tctgccgtga tggaaagaat cttgcgttgt tttaagatga gttttagagc ctgattgacc
    22381 acctcagcac ttttatttgg aatcaatcgg atgatctgat gtctactctt tcgatccgtc
    22441 aagacaagca agcagtagtt tttcgctctc gtaagtagaa ccgtatcaat ctcataatgc
    22501 ccattctcca agcgaagatt gatagcttca aaccgctgtt cgatggattg accagcaggt
    22561 ttaaagttgg tgctagcctg tttcttaagc gcttttcctt ttctagggta aagcagatcc
    22621 tgtttgctta accccaattt tccatgatga atccaatagt aaatggttga aattcccacg
    22681 ttaacccctt tagccatcac catcatttca ggcgaaaatt tttggttatg atagtggaga
    22741 atcttttcct ttagttcctt ggtcacgctt gatttcttga ccgagcgctt gcgattgttt
    22801 tcataagact gttgagcata gtcggcagaa taaacctctt tgaagcgccc ttttccaaga
    22861 cattgtcgga ctgtccc
//
LOCUS       DAVHBD010000039        22804 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000039 DAVHBD010000000
VERSION     DAVHBD010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22804
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.039"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..90
                     /locus_tag="VVK04_001583"
     CDS             <1..90
                     /locus_tag="VVK04_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU3990218.1"
                     /translation="FSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            240..494
                     /gene="blpM"
                     /locus_tag="VVK04_001584"
     CDS             240..494
                     /gene="blpM"
                     /locus_tag="VVK04_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU3990219.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGVPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            510..713
                     /gene="blpN"
                     /locus_tag="VVK04_001585"
     CDS             510..713
                     /gene="blpN"
                     /locus_tag="VVK04_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU3990220.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            957..1106
                     /gene="blpO"
                     /locus_tag="VVK04_001586"
     CDS             957..1106
                     /gene="blpO"
                     /locus_tag="VVK04_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU3990221.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1210..1329
                     /locus_tag="VVK04_001587"
     CDS             1210..1329
                     /locus_tag="VVK04_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU3990222.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            1797..2168
                     /locus_tag="VVK04_001588"
     CDS             1797..2168
                     /locus_tag="VVK04_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990223.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQIMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            2251..2634
                     /locus_tag="VVK04_001589"
     CDS             2251..2634
                     /locus_tag="VVK04_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU3990224.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2686..3375
                     /locus_tag="VVK04_001590"
     CDS             2686..3375
                     /locus_tag="VVK04_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3990225.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3417..3665
                     /locus_tag="VVK04_001591"
     CDS             3417..3665
                     /locus_tag="VVK04_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990226.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKNDV"
     gene            3695..4306
                     /locus_tag="VVK04_001592"
     CDS             3695..4306
                     /locus_tag="VVK04_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3990227.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            4467..5261
                     /locus_tag="VVK04_001593"
     CDS             4467..5261
                     /locus_tag="VVK04_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU3990228.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5258..5893
                     /gene="trmB"
                     /locus_tag="VVK04_001594"
     CDS             5258..5893
                     /gene="trmB"
                     /locus_tag="VVK04_001594"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU3990229.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6019..6498
                     /gene="rimP"
                     /locus_tag="VVK04_001595"
     CDS             6019..6498
                     /gene="rimP"
                     /locus_tag="VVK04_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU3990230.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6542..7678
                     /gene="nusA"
                     /locus_tag="VVK04_001596"
     CDS             6542..7678
                     /gene="nusA"
                     /locus_tag="VVK04_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU3990231.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7700..7993
                     /locus_tag="VVK04_001597"
     CDS             7700..7993
                     /locus_tag="VVK04_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU3990232.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7986..8285
                     /locus_tag="VVK04_001598"
     CDS             7986..8285
                     /locus_tag="VVK04_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU3990233.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8302..11094
                     /gene="infB"
                     /locus_tag="VVK04_001599"
     CDS             8302..11094
                     /gene="infB"
                     /locus_tag="VVK04_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU3990234.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11345..11695
                     /gene="rbfA"
                     /locus_tag="VVK04_001600"
     CDS             11345..11695
                     /gene="rbfA"
                     /locus_tag="VVK04_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU3990235.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            11974..12753
                     /locus_tag="VVK04_001601"
     CDS             11974..12753
                     /locus_tag="VVK04_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990236.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            12755..12937
                     /locus_tag="VVK04_001602"
     CDS             12755..12937
                     /locus_tag="VVK04_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990237.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            12934..13074
                     /locus_tag="VVK04_001603"
     CDS             12934..13074
                     /locus_tag="VVK04_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990238.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(13325..13402)
                     /locus_tag="VVK04_001604"
                     /pseudo
     CDS             complement(13325..13402)
                     /locus_tag="VVK04_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            13433..13666
                     /locus_tag="VVK04_001605"
     CDS             13433..13666
                     /locus_tag="VVK04_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU3990239.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            13666..15000
                     /locus_tag="VVK04_001606"
     CDS             13666..15000
                     /locus_tag="VVK04_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU3990240.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWIQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEESVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYSDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            15010..15264
                     /locus_tag="VVK04_001607"
     CDS             15010..15264
                     /locus_tag="VVK04_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU3990241.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            15360..15755
                     /locus_tag="VVK04_001608"
     CDS             15360..15755
                     /locus_tag="VVK04_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU3990242.1"
                     /translation="MSKKLNRKKQLRNGLRRSGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            16167..16616
                     /locus_tag="VVK04_001609"
     CDS             16167..16616
                     /locus_tag="VVK04_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEU3990243.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            16603..17160
                     /locus_tag="VVK04_001610"
     CDS             16603..17160
                     /locus_tag="VVK04_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3990244.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKVTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            17162..18124
                     /locus_tag="VVK04_001611"
     CDS             17162..18124
                     /locus_tag="VVK04_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEU3990245.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDINFTYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            18136..20787
                     /locus_tag="VVK04_001612"
     CDS             18136..20787
                     /locus_tag="VVK04_001612"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU3990246.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAIAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNIMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGCQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            20857..21612
                     /locus_tag="VVK04_001613"
     CDS             20857..21612
                     /locus_tag="VVK04_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU3990247.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            21891..22694
                     /locus_tag="VVK04_001614"
     CDS             21891..22694
                     /locus_tag="VVK04_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU3990248.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
BASE COUNT         6950 a         4071 c         5105 g         6678 t
ORIGIN      
        1 ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tgcgaatgaa tttgattgct
       61 ggcattatca atcatgaact aggattctag ttttgcagga agtctaatgt aatttttgca
      121 attcaagacg tttcgatgac tattcaagat ctggatgaaa aattttaaaa aacgatgata
      181 tactaaactt gtcaaagtta caacaagaca aaaattaaaa ataaaaaaga gtatttgtca
      241 tggatacaaa aattatggaa caatttcatg aaatggatat aactatgtta tctagtattg
      301 aaggaggcaa gaataattgg caaactaatg tcttagaagg tggtggtgct gcttttggtg
      361 gctgggggct aggaacagct atttgtgctg cgagtggtgt tggagtacca tttatgggag
      421 catgtggata cataggagct aaatttggtg tggatctttg ggcaggagta acaggggcaa
      481 cgggtggatt ttaataaaag gagacttgta tgaatactta ttgtaatata aatgaaacaa
      541 tgctgagtga ggtttatgga ggtaattccg gaggagcagc tgtagttgct gctttaggtt
      601 gtgcagcggg tggagtgaaa tatgggagac ttctaggacc atggggcgct gcaataggag
      661 gaattggagg agcagtggtt tgtggatatt tagcctatac cgctacatca taaaaatgaa
      721 agctaaattt tatgaaggct atattcttta ttattctctt cgcttttcaa acctatctta
      781 tttatctatc cataagtatc tccgataaaa aacaaaagac tattgaatta acatcattga
      841 attgttttgt catattattt ctaatctatg ataaattaat ttttctcttt attgcctatg
      901 tttttttgat aatttttata ttaaacttgt tccgtaactg aaaagtgaca tactatatga
      961 atacaaaaat gatgtcacaa ttttctgtta tggataatga aatgcttgct tgcgttgaag
     1021 gtggagatat tgattgggga agaaaaatta gttgtgcagc aggggttgca tatggcgcaa
     1081 ttgatgggtg tgcaacaacg gtttgacatt tctattggga ccatttgcta taggaatggg
     1141 tgtaactggt gctgcgggtg gagctatact tggaggtgta gcctatgcag caacatgttg
     1201 gtggtaatta tggattttaa aagttttatt attggtttag tagttggtat atttggtcct
     1261 tatatggata atttaattag aaaaatattt tcaaaatttc ccaaaaagga tacagatagt
     1321 accccctaaa aaataaattg ctcccctgta tttgctagct taatttacag gggagtttct
     1381 ttaatattgt ttcgcctgtc aaaatgatat gtgatagcag gatgaaaagt ctacaaacaa
     1441 gttggtatca atacaatata aagaggaaag tatgtttttc atgcttgctt ttttaatttt
     1501 tacaattcaa gaggttttga tgaccattta tgatttgagt gatccaaggt caaaataagt
     1561 gctatactag cagtgtaaat gttcttgctc aactaagata aatcgcacat ttaggaggaa
     1621 aacttatgaa gaaaaaaata ctgattattt tcgttctgta tctgatcatg tccatctttc
     1681 tttatccgct tagggagagt atatggtata atctatttta taccatagcc tatatgattg
     1741 cggttatgat ctatttttct ttaattaaaa agaaagaaaa gaaatgaaag attttcttga
     1801 ttaaaaagaa tcatattctt tgtgagattg ttcctgggtc agttgccttt gcttgtttct
     1861 acttatctat ttctatttcg tcagttttcc aatttctttt agtggttatt aacttggctt
     1921 ctattttggt cactgtttac ctcactaggg aaatgcggat aaaagagttt gaagacgatg
     1981 atttggttag tcctagaact aatcaaatca tgttcatcgg cttgacaggt tttatgtcta
     2041 ttatttgttt gtatagaggg atcacagcag gagaatccta ccaacaaata attgcctaca
     2101 ttggtgctat tctctgcttg accatcatgc ttctgctcat ttggggattg aagtattata
     2161 aaaagtagct ttctatcctt ttctgacagg atatttgagt agaaggctct attaaattgt
     2221 tagtgaaata aatgaatgga ggtatttaat atgaaataca gattattttt tgttattttc
     2281 ttgagtagtg tgttggatat tcttttaggg acatttttac aaatctctat cgtatctatt
     2341 gggtggcttg ttctttacag tggtttgttt gaagcaggag ttttccttct tgctaataaa
     2401 ggggtggcgg taaaaatcaa ggaagtagat attcgaaatc gctttaaatt tatttttgga
     2461 aaaaccttat ggtttcaaat tcttttgctc atctttttga taatcaaact ttatcttggt
     2521 ttggatgcga ggttgatttt attctatgga catattttca ttgtctttaa tgccttaatg
     2581 tatctattat ctagtagtca ggttagcctt aaaaaaaaca aactgtcttc ttaatcttac
     2641 agcagtagag cctgacaagg tgaggtcata gtagggagga tttctatgaa aaagtatcaa
     2701 cttctattca aaataagtgc agtcttctct tacttatttt tcgtatttgg tctttctcag
     2761 ctgacgctta tcgtccaaaa ttattggcaa ttttcttccc agattggtaa tttcgtctgg
     2821 attcaaaata tcttgagttt actttttatt ggagtcatga ttgtggttct tgttaagaca
     2881 ggccatggtt atctcttccg cattccaaga aaaaaatggc tttggtattc gattttgaca
     2941 gtattagtgg tagtgttcca gatctctttt aacgttcaga cagctaaaca tgttcagtca
     3001 actgcggaag gttgggctgt attgattggt tatagtggga ctaactttgc agagctaggt
     3061 atttatatag ccctgttctt tctggttcca ctgatggaag agttaatcta tagaggatta
     3121 ctgcaacatg ctttctttaa gcattcgcga tttggtcttg atttgcttct tccttctatt
     3181 ttatttgctc tccctcattt ttcaagcctg cctagtctgt tagatatctt cgtctttgca
     3241 acagttggaa tcatctttgc tggtttgacc cgctatacca agagcattta tccatcctat
     3301 gcggtgcatg tgatcaataa tattgtagcg accttcccgt ttttgctcac ttttctacat
     3361 agggtcttgg ggtaaaaaaa caaaaggctt gcttttcagc catagaggag gtcatcatgt
     3421 ataaacactt atttttccta gattccaaaa ctttagatcg gttgacaccc tatattctag
     3481 tcttggcttc tgacaccatt gcttttaatg tttttgtgct aacctttgta tctgcggtgg
     3541 tttttaattt cctaaattcc atgctagctt taatggctat attcataggg gctggctatg
     3601 tggtcggatt ttggttgcta aaatggtttg ttttggaaag gctagaacta aagaatgacg
     3661 tgtaggaagt ctgtttgttg aggaggataa ttttatggag ttttttgata aatttcatgc
     3721 cttgtgtttt ggatttttag tactaataat tgtcattaca gttccttata cgattaacca
     3781 tggggatttt tttcaaaatg aatctgcatt gattattgta agtcttcttg taacctcgct
     3841 gagtgttgct tatgctagaa agtttgaaat gatttctttt gggatgttaa gcaagaaaca
     3901 acttttgctt ttcattgcaa tctttcttct aagtgtactt gagacgctgg tttatattca
     3961 tttcttcgct gtttcttctg gctcaggggt ccaacacttg gcggaagtca gcagaggaat
     4021 ttccctgtct ttgattttga ctacctcagt ttttggcccc atccaggagg aactcatttt
     4081 cagaggactt cttcaaggtg cggtttttga caattcttgg ttagggcttg tgctaacttc
     4141 ctctctcttt tctttcatgc atggaccttc taatgtccct tcgtttattt tttatctact
     4201 tgggggcttg ttgctgggcc ttgcttataa aaagagccaa aacctatggg tttctactct
     4261 agtccacatg ttttacaaca gttggccact cctatattat ttataaaaat tatgaaaagg
     4321 taagcagaag acggtgctta cctttttcaa gctataatga tacccaagcc aatccagagg
     4381 cttttctttg agaatcgggt tagagtggtt gacgaatagg ccaaaaacta gtagaatagt
     4441 aaggaaactt tatacggagg aaagaaatgg atttgggtga taatgagcta acactgactc
     4501 ccatacctgg gaaaagtggc aaggcttata tgggtagcta tcctgatggg aagcgcatct
     4561 ttgtaaaaat gaacacctct ccaatcctac ctggtctagc tagagaacaa attgctccac
     4621 aattattatg gagtcgtcgt ttggcagatg ggcgtgatat gtgtgctcaa gaatggttga
     4681 caggcaagat attgaccccc tatgatatga atcgtaagca aatcgtcaat attttaaccc
     4741 gtcttcatcg ctcacgtccg ttgatgacac aattgagtcg tttgggctat gccatggaaa
     4801 cacctgtaga tttactacag tcttggcaag aaacggctcc agatgctttg cgtaaaaatc
     4861 attttatcag tgaagtgatg gctgatttgc gtcagactat tccaggattt agagaggacc
     4921 atgcgaccat tgtccatgga gatgtacgac atagtaattg gattgagaca gatagtggct
     4981 tgatttattt agtagattgg gattcggttc gcttgaccga tcgcatgttt gatgtggccc
     5041 atatgctctg ccattatatt tcagaacatc agtggaagga atggttgacc tactacggtt
     5101 acaagtacaa tcaaacggta ttaagtaaat tgtattggta tggtcaattg tcttatttga
     5161 gtcagatttc caagtattat atgaaccaag atttagaaaa tgtcaatcgg gagattcatg
     5221 gtttgcgtca tttccgagac aagtatggaa agagaagatg agagttagaa atcgtaaagg
     5281 ggcaacagaa ttactagagg caaatcccca gtatgtggtc ctcaatccct tggaagccaa
     5341 ggcaaaatgg cgggacttgt ttggcaatga taatcccatt catgtggaag ttggaagtgg
     5401 aaagggtgcc tttgtttcag gtatggccaa gcaaaaccct gacatcaact atatcgggat
     5461 tgatattcaa aagtctgttt tgagctacgc tttggacaag gtgcttgaag ctggagtgtc
     5521 taacatcaag ctcttgtggg tagatggttc tgacttgact gactactttg aagacggtga
     5581 gattgatcgc ttgtatctga acttttcaga tccatggccg aaaaaacgcc atgaaaagcg
     5641 tcgtttgacc tacaagacct ttttggatac cttcaaacgt atcttgcctg aaaatggaga
     5701 aattcatttc aagacggata accgtggctt gtttgagtac agtttagtga gcttttctca
     5761 atatggcatg aaactcaatg gtgtctggct agatttgcat gccagtgatt ttgaaggcaa
     5821 tgttatgaca gaatacgagc aaaaattctc aaacaagggg caagttatct accgagttga
     5881 ggcagaattt taagagatag cctaaaatta ggctgtacaa gtgcttttgc tttacataag
     5941 ttggcaaacg tgctatactg atagtaagaa tatgaaaagt gaggcgggga aatatcttcg
     6001 cctcttgctt atgaggaggt ggacgcaatc gcaacaatcg tagaattagt cagagaagtt
     6061 gtagaacctg tcatagaagc tccttttgaa ctcgtggata tcgagtatgg aaagattggc
     6121 agtgacatga ttctcagtat ttttgtagat aaacccgaag gaattacctt gaacgacacg
     6181 gcagacttga cagaaatgat cagtcctgtc ctagacacca tcaagccaga tcccttccca
     6241 gaacaatatt tcctagaaat taccagtcca ggtttggaac gtcctttgaa aaccaaggat
     6301 gccgtcgctg gagcggttgg aaaatacatc catgtcgggc tctaccaagc catcgataag
     6361 caaaaggtct ttgaaggaac cttgttggcc ttcgaagagg acgagttgac tatggaatat
     6421 atggacaaga cgcgtaagaa aaccgtccaa attccataca gtttagtatc aaaagcacgt
     6481 ttagcagtta aattatagaa aaagaaagga tagcttttga ggattcaaaa gtgaagaaaa
     6541 catgagtaaa gaaatgctag aggccttccg cattttggaa gaagacaagg gaatcaaaaa
     6601 agaagatatc atcgacgcag tagtagagtc gcttcgttcc gcttatcgca gacgctatgg
     6661 tcagtcagac agcgtagcta ttgacttcaa cgaaaaaaca ggtgacttta cagtttatac
     6721 tgtccgtgaa gttgttgatg aagtatttga tagccgtttg gaaatcagct tgaaagatgc
     6781 tcttgccatt aattcagctt atgaacttgg agacaaaatc aagtttgaag aagcaccagc
     6841 tgagtttggt cgtgtagcag cccagtctgc caaacaaacc atcatggaaa aaatgcgcaa
     6901 gcaaacacgt gccatcactt acaatactta caaagaacat gagcaagaaa tcatgtctgg
     6961 tacagtagaa cgctttgaca accgctttat ctatgtcaac cttggtagca tcgaagccca
     7021 attgtcaaaa caagaccaaa ttcctggaga agtttttgct tctcatgatc gtatcgaagt
     7081 ttatgtttac aaggttgaag acaaccctcg tggtgtgaac gtctttgtta gccgtagcca
     7141 tccagaaatg atcaaacgtt tgatggagca agaaattcca gaagtttatg atggaactgt
     7201 tgaaatcatg agcgtggctc gtgaagcagg tgaccgtacg aaggttgctg ttcgtagcca
     7261 caatccaaac gtggatgcta tcggtacaat cgttggacgt ggtggtgcta atatcaagaa
     7321 gattactagc aaattccacc cagctcgtta cgatgctaaa aatgaccgca tggtaccaat
     7381 cgaagaaaat atcgatgtta tcgagtgggt agcagatcca gctgaattta tctacaatgc
     7441 catcgctcct gctgaggttg accaagttat ctttgatgaa aacgacagca aacgtgcctt
     7501 ggtggttgtt ccagataaca agctttctct tgccattggt cgtcgtggac aaaacgtgcg
     7561 cttggcggct cacttgactg gttaccgtat cgatatcaag tctgctagcg aatttgaagc
     7621 catggaagac gctgcttcag tagagttgga agtagaaaac gatactgtag aagaataaaa
     7681 gctgctagag gagggaaaga tgaaaacaag aaaaatccct ttgcgcaagt ctgttgtgtc
     7741 taacgaagtg attgataagc gtgatttgct ccgcattgtc aagaacaagg aaggacaagt
     7801 ctttattgat cctacgggca aggccaatgg ccgcggcgct tatatcaaac tagacaatgc
     7861 agaagcccta gaggcgaaaa agaagaaggt ctttaaccgc agctttagca tggaagtgga
     7921 agaaagcttt tatgacgagt tgatcgctta tgtggatcac aaagtgaaaa gaagagagtt
     7981 gggacttgaa taagcaaaag ataagtaatc tcttggggct tgctcagcga gcagggcgca
     8041 tcatatcggg tgaagaattg gtggtcaagg ccattcaaga cggcaaggcc aagttggtct
     8101 ttctagctca tgatgctgga cccaatctga ccaagaagat tcaagataaa agtcattatt
     8161 atcaagtaga aattgtaacc gtgttttcaa cactggaatt aagcatagca gtcgggaaat
     8221 cgagaaaggt tttggctgta acagatgctg gatttacaaa gaaaatgagg tctcttatgg
     8281 aatagaagag gaggacatga tttgtctaag aaaagattgt acgaaatcgc aaaagaactt
     8341 ggaaaagaaa gtaaagaagt tgtagcgcgt gcaaaagagt tgggcttgga tgtgaaaagc
     8401 cactcatcaa gtgtggaaga agctgtcgct gcaaaaattg ctgccagctt taagcctgca
     8461 gctgctccga aagtagaagc aaaacctgca gcaccaaaag taagtgcaga aaagaaaacc
     8521 gaaaaatctg agccagctaa accagctgta gctaaggaag aggcaaaacc ggctgagcca
     8581 gttgctccga aaacagaaaa agtagcagcg aaaccgcaaa gccgtaattt caaggctgag
     8641 cgtgaagccc gtgctaaaga gcaggcagaa cgacgcaagc aaaataaggg caataaccgt
     8701 gaccaacaac aaaacggaaa ccgtcagaaa aacgatggcc gtaatggtgg aaaacaaggt
     8761 caaagcaacc gcgacaatcg tcgctttaat gaccaagcta agaagcagca aggtcagcaa
     8821 aaacgtagaa atgagcgccg tcagcaagag gacaaacgtt caaatcaagc ggctccacgt
     8881 attgacttta aagcccgtgc agcagcccta aaagcagagc aaaatgcaga gtacgctcgt
     8941 tcaagtgagg aacgcttcaa gcagtatcag gctgctaaag aagccttggc tcaagctaac
     9001 aaacgcaagg aaccagagga aatctttgaa gaagcggcta agttagctga acaagcacag
     9061 caagttcaag cagtggttga agtcgtccct gagaaaaaag aacctgcagt ggatacacgt
     9121 cgtaaaaaac aagctcgacc agacaaaaat cgtgacgatt atgatcatga agaagatggt
     9181 cctagaaaac aacaaaagaa tcgaagtagt caaaatcaag tgagaaatca aaagaatagt
     9241 aactggaata acaacaaaaa gaacaaaaaa ggcaataaca agaacaaccg taatcagact
     9301 ccaaaacctg ttacggagcg taaattccat gaattgccaa cagaatttga atatacagat
     9361 ggtatgaccg ttgcggaaat cgcaaaacgt atcaaacgtg aaccagctga aatcgttaag
     9421 aaacttttca tgatgggtgt catggccaca caaaaccaat ccttggatgg ggaaacaatt
     9481 gaactcctca tggtggatta cggtatcgaa gccaaacaaa aggttgaagt ggataatgct
     9541 gacatcgaac gtttctttgt cgaagatggt tatctcaatg aagatgaatt ggttgagcgt
     9601 ccaccagttg ttactatcat gggacacgtt gaccacggta aaacaaccct tttggatact
     9661 cttcgtaact cacgtgttgc gacaggtgaa gcaggtggta ttactcagca tatcggtgcc
     9721 taccaaatcg tggaaaatgg taagaagatt accttccttg atacaccagg acacgcggcc
     9781 tttacatcaa tgcgtgcgcg tggtgcttct gttaccgata ttacgatctt ggtcgtagcg
     9841 gcagatgacg gggttatgcc tcagactatt gaagccatca accactcaaa agcagctaac
     9901 gttccaatca tcgtagccat taacaagatt gataaaccag gtgctaaccc agaacgcgtt
     9961 atcggtgaat tggcagagca tggtgtgatg tcaaccgctt ggggtggaga ttctgaattt
    10021 gttgaaatct cagctaaatt caaccaaaat atcgaagaat tgttggaaac agtccttctt
    10081 gtagctgaaa tccaagaact caaggcagac ccaacagtgc gtgcaatcgg tacggttatc
    10141 gaagcgcgct tggataaagg aaaaggtgcg gtcgcaaccc ttcttgtaca acaaggtacc
    10201 ttgaatgttc aagacccaat cgttgtcgga aataccttcg gtcgtgtccg tgctatgacc
    10261 aacgaccttg gtcgtcgtgt taaagttgct ggaccatcaa caccagtctc tatcacaggt
    10321 ttgaacgaag caccgatggc gggtgaccac tttgccgttt acgaggatga aaaatctgcg
    10381 cgtgcagcag gtgaagagcg tgccaaacgt gccctcatga aacaacgtca agctacccaa
    10441 cgtgttagcc ttgaaaacct ctttgatacc cttaaagctg gggaactcaa atctgttaat
    10501 gttatcatca aggctgatgt acaaggttct gttgaagccc tttctgcctc acttcaaaag
    10561 attgacgtgg aaggtgtcaa agtgactatc gtccactcag cggtcggtgc tatcaacgaa
    10621 tcagacgtga cccttgccga agcttcaaat gcctttatcg ttggtttcaa cgtacgccct
    10681 acaccacaag ctcgtcaaca agcagaagct gacgatgtgg aaatccgtct tcacagcatt
    10741 atctacaagg ttatcgaaga gatggaagaa gctatgaaag ggatgcttga tccagaattt
    10801 gaagaaaaag ttattggtga agcggttatc cgtgaaacct tcaaggtgtc taaagtggga
    10861 actatcggtg gatttatggt tatcaacggt aaggttgccc gtgactctaa agtccgtgtt
    10921 atccgtgatg gtgtcgttat ctatgatggt gaactcgcaa gcttgaaaca ctataaagat
    10981 gacgttaagg aagttacaaa cggccgtgaa ggtggattga tgatcgacgg ctacaatgat
    11041 attaagatgg atgatgtgat tgaggcgtat gtcatggaag aaatcaagag ataagatttt
    11101 ttgctccttt cttaggtggt gagggacgca agcaaaccga tggtttcatt gcttattttt
    11161 gagcctaggg tctcaaaaat cccctgtgat gggactgata aatcagttcc atcactttca
    11221 ccacggcgaa agaagcagat gacttcaaat tgaacttcgt ttcaatttaa actgaaaatc
    11281 aagaagttta aaatagctag gtctgctggc ctagcttttg gttcaaagta gagaaaggaa
    11341 tatcatggca aatcatttcc gtacagatcg tgtgggcatg gaaatcaagc gtgaagtcaa
    11401 tgagattttg caaaagaaag ttcgtgatcc acgtgtccaa ggtgtgacca tcacagatgt
    11461 tcagatgttg ggtgacttgt ctgttgccaa ggtttattac accattttga gtaaccttgc
    11521 ttcggataac caaaaagccc aaatcgggct tgaaaaagca actggtacca tcaaacgtga
    11581 acttggtcgc aatttgaaat tgtacaaaat cccagatttg accttcgtca aagacgagtc
    11641 catcgagtat ggaaacaaga ttgacgagat gctacgcaat ctggataaga actaaagaag
    11701 aggggttgcc cctctttttt ggtggaggaa aataggttga atttgaaatg gaaaaatatt
    11761 cttttaaaat atattgaaac tagaatagta cgcctctact tctaaaacat tgttagaaat
    11821 cgatttgact gtcctgatcg atttgtcctg ttcttgtttc attttactat aaaaaagggg
    11881 ttctgtattt tttaatgtta tctaattaga aaatgctttt tttgtaggaa atataatatg
    11941 ataaggtgta aaaaagaaat aaggagtttg tatatggctg aacaagactt agctatgcaa
    12001 gtattacaac aagtggtaaa actaccagtt gttaaggttg atcgttcgaa atttttagtg
    12061 gataagtttt ccaaagaatt gggtccacag gacattccta ccttattgga acaaggtcca
    12121 acgtctctct tatctcaaga aatcttagat cgagtggcta atgcctgtat tagggataat
    12181 gttttattag cgagtgggac ttctgttttg gcaggattac ctggagggct tgctatggca
    12241 attaccattc cagctgatgt ggctcaattt tatggtttct ctctgaaatt ggcccaagaa
    12301 ttaggttata tttatggtta tgaggatctt tgggcttcac gcgatgagtt gagtgaagat
    12361 gctcaaaata cccttttgct ttatctaggc gtcatgttgg gggtgaatgg aactgctgct
    12421 ttgctacgtg ctggtggtat aacaattgcc aaacaggtaa tgaaaacagt acctaataaa
    12481 gctttaacaa agacgctttg gtatcctatt ttgaaaaaag tcttaagaat atttggtgtg
    12541 aatcttacca agggagggct ggccaaagga atggggaaat ttattcctat cttgggtggt
    12601 atcatttcag gtggtttaac ctttgcaact atgaaaccga tgggtgaaag cttgcagaaa
    12661 gaattgtcca agctagttaa ctatagtgaa gttcaatatc aagaagatgt tgaaacaatc
    12721 cgaaaagagg ctgaaatcat cgaaggagag taatatggga ctcataaaaa ctctagctaa
    12781 aatttatggt aattactttt tgaccgtgca aggtgtaaaa gtaatgaaaa cgataaagaa
    12841 agatgataat gccgttgtcg gtctggggaa actttttatt gccgacaagt taatggatac
    12901 ggctcggtgg ctcattaagc cagaggagag agaatgaaat ttttctgggg acttcttgcc
    12961 attattttta tcaaaccgat tattgggatt gtgaaattct tttggatgat catttctttt
    13021 gcagttcaat tgctgtttta caagatattg gattggttct ttaaacttat ctagatggta
    13081 atccaagtcg cagaaaacta gcaggaactc cactgctagt tttttaatct ctctccatat
    13141 ggtataatat aagcagtaaa atcattttat actcttcgaa aatctcttca aaccacgtca
    13201 gcttcacctt gcagtaggta tggttactga cttcgtcagt tctatccaca acctcaaaac
    13261 ggtgttttga gctgacttcg tcagttctat ccgcaacctc aaaacggtgt tttgagctga
    13321 cttcgtcagt tctatctaca acctcaaaac actgttttga gcaacctgcg gctagcttcc
    13381 tagtttgctc tttgattttc attgagtatt agaagataca atggaggtcg tcatggacaa
    13441 tatcatcgat gtgtcaattc ctgttgcaga agtggtggac aagcatccag aagtcttgga
    13501 aattctagtg gagttgggtt ttaaacccct tgccaatccc ttaatgcgca atacagttgg
    13561 tcgtaaagta tcacttaaac agggttctaa gctagcagga actcctatgg acaagattgt
    13621 acgcacactg gaagcgaatg gctacgaagt gattggatta gactaatgac agatgaacgg
    13681 attcatatcc tacgggatat tttgttagaa ttgcacaatg gcgcctctcc tgagtcggtt
    13741 caagatcgct ttgatgcgac ctttacgggc gtgtcagcca tcgagatttc ccttatggag
    13801 cacgagctga tgaactcgga ttcgggcgtc acttttgaag atgttatgga actctgtgat
    13861 gtccatgcca atctttttaa aaatgctatc aaaggtgtcg aagttttaga taccgaacac
    13921 cctgggcacc cagttcgtgt ctttaaggaa gaaaatttgg ccctccgtgc agctttgatt
    13981 cgcattcgta gattgttaga tacctatgag ttgatggaag acgaggaaat gctggcggag
    14041 atgcgcaagg gcttggtgcg tcagatggga cttgtggggc aatttgacat ccattaccaa
    14101 cgtaaagaag aactcttctt tcctatcatg gagcgctatg gacacgattc acctcccaaa
    14161 gttatgtggg gagtggatga tcagattagg gaactctttc aaacagctct aacgacagcc
    14221 aagtcactac cagaagtgtc aattagcagt gtaaaggaag cttttgaagc ttttgcgaca
    14281 gagtttgaaa gtatgatttt caaggaagag tccatcctcc tcatgattct ccttgagtct
    14341 tttactcagg atgactggat tcagattgcg gaggagagcg atgcctatgg ctatgccatc
    14401 atccgtccgt cagagaaatg ggtgccagaa cgacagagct ttattgagga aaagattgca
    14461 gaggagtctg tacagctaga tacggcagaa ggtcaagttc aacaagtcat agatacgcca
    14521 gaaggccatt ttaccattac ctttacccct aaggaaaagg aagctgtgct ggaccgccat
    14581 agtcaacagg cttttggtaa tggctatctt tcagtcgagc aggccaatct catcctcaat
    14641 catctcccta tggagattac ctttgtcaat aaagaagata ttttccagta ttacagtgac
    14701 aatacgccag ctgatgagat gattttcaaa cgaacgccgt cccaagtcgg gcgcaatgtc
    14761 gaactctgtc atccgcctaa gtatttggac aaggtcaagg ctatcatgaa gggacttcgt
    14821 gaggggacca aggacaagta tgaaatgtgg ttcaagtctg agtcgcgagg caagtttgtc
    14881 cacatcacct atgctgcagt acacgatgaa gacggagaat tccaaggagt gttggagtat
    14941 gttcaggata tccagcccta ccgtgagatt gatacggact atttccgtgg attagaataa
    15001 ggagaaaaaa tgagttacga acaagaattt atgaaggaat ttgaagcttg ggtcaatacc
    15061 caaatcatga ttaacgatat ggcgcacaag gaaagtcaaa aagtttacga agaagaccag
    15121 gacgagcgtg ccaaagatgc catgattcgc tacgagagtc gcttggatgc ttatcagttc
    15181 ttgcttggta agtttgaaaa cttcaaagca ggcaagggat tccatgattt gccagaaggc
    15241 ttgtttggtg agcgaaatta ttaaacgaga aagattcttg atttttcact aaaatcttga
    15301 tagaatgttt atgttaaatc cttgtcagag cagggatttt ttattgaaag gattttatca
    15361 tgtcaaagaa actcaatcgt aaaaaacaat tacgaaatgg cctccgtcgc tcaggtgcct
    15421 tttcaagtac tgtgactaag gttgtagatg agacaaaaaa agtcgtgaag cgtgcagaac
    15481 agtcagcaag cgcagctggt aaggctgttt ctaaaaaagt tgaacaagca gtagaagcta
    15541 ccaaagagca agctcaaaaa gtagctaatt ctgtagaaga ttttgcagca aacttgggtg
    15601 gacttccact tgatcgtgcc aagactttct atgatgaagg aatcaagtct gcttcagatt
    15661 tcaaaaactg gactgaaaaa gaactccttg acttgaaagg aatcggccca gctaccatca
    15721 agaaattgaa agaaaatggc atcaagttca agtaattttt cttgagcctt gcatttccga
    15781 gaaaaacttg ctacaataga gccattagag gtgttttgaa tcccacattt tacagaaagt
    15841 ggcggcgctg agaagtccac aaatgtgtca aaactggttg ctaatgactg aaaaaatgaa
    15901 atatttctgt ctttttattt taaagactaa agatgcgggc ttggcccgaa attgggtggt
    15961 accgcggata aacacattcg tccctgtcat gtagatggca gggcttttct tttgtgtctt
    16021 agtcaaagga ggttgttata aaacaatcat ttaaaactaa taaactatat tatggttttc
    16081 ctgtttttat tttaggatat caagattaga attttggcta taacatcacg acctgtaatt
    16141 cctcttatag tctaggagat tgggttgtga ttggagtcgt tgcgagagag aatgccgcag
    16201 agcagatcaa acagtatcaa aaatttactg tgaatatttc tgatgaaact tctatgcttg
    16261 cgatggagca ggctggtttt atcagtcatc aggagaaatt ggaacgtttg ggagtgcatt
    16321 atgaaatttc tgaacgaact cagattccta ttttagacgc ctgtccactt gttttagatt
    16381 gtcgggtaga taggattgtt gaggaagacg gtatttgcca catctttgcc aagattcttg
    16441 agcgacttgt tgccccagaa ctcctggatg aaaagggaca ttttaaaaat caactgtttg
    16501 ccccaaccta tttcatggga gatggatatc agcgcgttta tcgctatctg gataagcgtg
    16561 tagatatgaa gggcagtttc atcaaaaaag cgaggaagaa ggatggcaag aactgagctg
    16621 ccagataaaa tcgaaacaga acgtctcgtt ttacgagtcc gtactgtggc ggatgctgag
    16681 gatatctttg actatgctag tttgccagag gtcgcctatc cagcaggttt tcctccagtc
    16741 aagaccttgg aagatgagat ttattatctg gagcacattc ttccggagcg taatcaaaag
    16801 gaaaatcttc cagcaggcta cgggattgtc gtcaaagtaa cggataagat cgttggctct
    16861 gtcgatttca accatcgcca tgaagatgat gtgctggaaa tcggctatac cttacaccca
    16921 gactattggg ggcgaggtta tgtgccagaa gctgcgcgtg ccttgattga cttagccttt
    16981 aaagatttgg gtcttcacaa gattgaacta acttgctttg gatataacct tcaaagtaaa
    17041 cgagtcgcgg aaaagcttgg ctttaccctc gaagctcgca taagagaccg aaaggatgtt
    17101 caaggaaacc gctgtgacag tctgatatat ggcttgctga agagcgagtg ggaggaataa
    17161 gatgagcgat gtaaaagagg aagtaagctc tctatctgag aagcagttac gccaaattga
    17221 tgttgagtat gctgaattaa atgatagtga tattatcgag cgattagctt atttagaaat
    17281 taacaacaat gaaaaacgta ttgtcatctc tgatattgaa ccaaccaagg aaataatgtc
    17341 agtctcggac caaatttttg agattcaaaa gaattttcaa aaaatcaaga atatgttcga
    17401 attgtttatt tcagatgtct cggatttttt aagtattaaa aataaacttg agtcaaagga
    17461 attagaaatt gaagaggcag atgtaaatcg tttcatgatt catttattat ccagtggaaa
    17521 attgtttgtc gattttaacg aaaaccaaat taaacaaaaa tattccaaag atagtgagga
    17581 gtttgattgt atacatggtt ttgcaagcta tcagtatgat atcaatttta cttatcgatt
    17641 ttgccattct ttgagaaatt attcgcaaca tactgactta ccaataaatg aggtaaaagc
    17701 tgttagccca gatgatgaga ctgttataat agatttctat attgatttag attatctttt
    17761 aaattccaac tttaaatgga aaaaattgaa aggggagttg ataaaactaa accaagaaac
    17821 atctaagatt gacgctatag ctctagtgaa agaatacttt aatgctctta cagagctcta
    17881 tggtaattat aataagttgt ttttaaagtt aaaccataat acattagtag atattaaatc
    17941 aaagttggaa tcattaaaat tgaaacactc taggtattat atttcaaaga taagcaagta
    18001 tgatcttaaa tataatcctg gaaattatac tatgtcacca cttgcagcat ttgctgaaat
    18061 tgaagagatt tatattgaac tttcaaaaat tggtttggtt aaaattgtca ataaaagtaa
    18121 ttaaggagaa cacacatgtc taaagaactt tcatctaaat acaatccagc cgaggttgag
    18181 gctggtcgtt accaaaaatg gcttgatgct gatgttttca agccttcagg cgatcaaaag
    18241 gctaagcctt attcaatcgt tattccacca ccaaacgtta caggtaaact tcaccttggt
    18301 cacgcttggg atacaacttt gcaagatatt atcatccgtc aaaaacgcat gcaaggtttt
    18361 gatacccttt ggcttcctgg gatggaccac gcagggattg ccactcaggc taaggttgag
    18421 gagcgcttgc gtggtgaggg catttcccgc tatgaccttg gtcgtgagtc tttcttgacg
    18481 aaagtctggg aatggaaaga cgaatatgcc actaccatca aggaacaatg gggcaagatg
    18541 gggctctctg tagactattc tcgtgagcgt ttcactcttg acgaaggttt gtcaaaagct
    18601 gttcgtaagg tctttgtgga cctttacaag aaaggctgga tctaccgtgg tgagtttatc
    18661 atcaactggg acccagcagc tcgcacagcc ctttctgata ttgaggtgat tcacaaggat
    18721 gtggaaggtg ccttctacca catgaattac atgctggaag atggttcacg cgcccttgaa
    18781 gttgctacaa ctcgtcctga gactatgttt ggggacgttg cgattgcggt taatccagaa
    18841 gacccgcgct acaaggactt gattggtaaa aacgtcatcc ttccaatcgc taataaactc
    18901 atcccaatcg ttggagatga gcacgcagat cctgagtttg gtactggtgt cgtgaaaatc
    18961 acacctgccc acgatccaaa tgacttcttg gttggccaac gtcataactt gccacaagtc
    19021 aacatcatga acgacgacgg aactatgaac gagcttgcct ttgaattttc aggcatggat
    19081 cgttttgaag ctcgtaaggc agtcgttgct aagttggaag aaatcggtgc ccttgtcaaa
    19141 atcgaaaaac gtgtccacag tgttggtcac tcagaacgta caggtgtcgt agttgagcca
    19201 cgcttgtcta ctcaatggtt cgtcaagatg gaccaattgg ctaagaacgc cattgccaac
    19261 caagacacag aggacaaggt cgaattctac ccacctcgtt tcaacgatac cttccttcaa
    19321 tggatggaaa atgtccacga ctgggttatc tctcgtcagc tctggtgggg tcaccaaatc
    19381 cctgcttggt acaatgctga tggtgaaatg tatgtcggcg aagaagctcc agaaggtgac
    19441 ggatggactc aggacgaaga cgtcttggat acttggttca gttctgccct ctggccattt
    19501 tcaaccatgg gctggcctga agtcgactca gaagacttta aacgttattt cccaacttca
    19561 accttggtaa caggttacga catcatcttc ttctgggtgt ctcgtatgat cttccagtca
    19621 ttggaattca caggctgtca accattccaa aacgtcctta tccacggtct cattcgtgac
    19681 gagcaaggac gcaagatgtc taagtctctc ggtaacggga ttgacccaat ggatgttatc
    19741 gagaaatacg gtgccgatgc ccttcgatgg ttcctttcaa acggttctgc gccaggacaa
    19801 gacgtgcgtt tctcttatga gaaaatggat gcttcatgga actttattaa caagatttgg
    19861 aacatttctc gctatatcct catgaacaat ggaggtttga cgctggatgt ggcgcatgac
    19921 aatgtcacaa aagttgcaac aggtgaggct ggtaatgtga cggaccgctg gattctccac
    19981 aatctcaacg aaaccattgc aaaagttact gaaaactttg ataagttcga gtttggtgtg
    20041 gctggtcata tcctttacaa cttcatttgg gaagaatttg ccaactggta tgttgagttg
    20101 accaaggaag ttctttacag cgacaatgaa gacgataagg taattactcg atctgttctc
    20161 ctctatacgc tggataaaat ccttcgtctc cttcactcaa taatgccgtt cgtgacagaa
    20221 gaaatctttg gtcagtacgc tgaaggctct atcgtgacag cagcataccc aactgtcaac
    20281 ccagcctttg aggaccttgc tgcccacact ggtgtggaaa gtctcaaaga cttgatccgt
    20341 gccgttcgta atgcgcgtgc ggaagtaaat gtagcaccaa gcaaacctat caccatcctt
    20401 gttaagacta gcgatagtga cttggaagcc ttctttaaca gcaatgtcaa ctacatcaaa
    20461 cgctttacaa atccagaaca cttggaaatc gcatcaacca tccctgcacc tgaactggct
    20521 atgtcaagcg ttattacagg agccgaaatc ttcttgccac tggtagacct cttgaatgtc
    20581 gaagaagaat tggcacgtct ggaaaaagaa cttgccaaat ggcagaaaga actcgacatg
    20641 gttggcaaaa aactcagcaa cgaacgcttc gtcgccaacg ctaaaccaga agttgtccaa
    20701 aaagaaaaag acaaacaagc cgactaccaa gccaagtatg atgtgaccgt agcacgtatt
    20761 gatgagatga agaagttggt gaaataaaca cagaaacacg gtgatgagcc gtgttttttg
    20821 gtataatgaa atcaatatct attgatggag aaagtgatgt ccaaacaccc tcattatgaa
    20881 ttgttaaatt taattggcta cggtcttgcc aagtttgaca agctttttat aaaagaattt
    20941 caatgctcta gcaagtcgga gttttatcgc tatgtggttt ctctgggaat tgctgaaaca
    21001 actggagttg taaaaaatag aatggattta tttgatcctt attttgacaa taatcgaaaa
    21061 ggttggtggc agaaagctga agtttatcgt tttcgtaaag atttaattga tatgatgttt
    21121 ggaaatgaag atgttcatag ttatgctgaa atagttaaaa tgttacttgc cagtgaaggg
    21181 aagaaaacag gcataaccat cgttgaaaaa ccaatagttc gaactaaatt caaacgtcta
    21241 caggaaacgg gaatggaggc tgagaattat tttatccttc attttgataa agaagaaaaa
    21301 ttccaaggtg gacagttaac cgatgcccgt ctttatggtg atggatatga ctttcaggta
    21361 gatgtccaag agtattctta ccttgccgaa gtaaaaggta tccgaaaatc taaggggcgt
    21421 gtgcgtttaa ctgcaaaaga atttgaaaaa gtcaaggagt ttcaatcgga ttttatttta
    21481 tccttggtca caaatctaga tgatattcca aagttagtgt taatcgataa tcctttaaaa
    21541 cattttgagt ttaaaaagaa tattatcaaa aatgaaatca ttgaatatag aagcgtagag
    21601 gatttgtatt agttccccct taacttttcc agttgaagga acgagaagtc ttgacaggtc
    21661 aacgacttaa tgaactggaa atcaacggta ttcgtttgac taagttttaa gatggcgaaa
    21721 tcggtattga atttatcagt agtgctgatt ataactcttt tattatttac atgaagtata
    21781 tatatatata tcatagaacc tattgtgagg actttttata gtttaagcca gtttccaacc
    21841 aatttcgtga tttactggta atgaagaaaa acaattgaaa ggatatttct atgcaaccaa
    21901 cttacaacat tgacaatcca aacttgtctt atgaagcgaa gcgtgattta tggcggatag
    21961 gttttggtct gcagaaagtt gacaatctag tgccatcagc gtatatggaa tctttggctg
    22021 agaaacagtc ccggggagaa ctgacttatg agcaggttta tgaggatgca acggcttatc
    22081 accatactat tgatgcaagt acggaagagg cagacttggt ttctctacgt attgtagaac
    22141 tattgtctcg aagaggcttt agctttagtc ctgcgacctt acttgctatt cataaggagt
    22201 tgtttcaaga tatatttgaa ccctctattc cggtggggca atttcgtcag accaatatca
    22261 caaagaatga acctgttttg aatggtgaaa gtgttgtgta ctctgattac tccatgattc
    22321 aaatgacctt agattatgat tttaatcagg aaaaacaagt tgcatatgcg acactaactc
    22381 aggcggatgt ggttaaacaa atccagcatt ttatttcagg aatctggcag attcatccat
    22441 ttcgcgaagg aaacactcgg acagtaacgg tctttttgat tcagtatctt cgtgagtttg
    22501 gttttgatat tgataataca ccatttcagc aacattccaa atattttcgt gatgccttgg
    22561 tattagataa tgcaaagatt ttacagcgac gttctgagtt tttaacagct ttttttgaaa
    22621 atctcttgct cggtggtcaa aatgatttgt cttcagaaaa aatgtatcta gatttagacc
    22681 tcgatttttc ataatccaaa tactgagtaa acattgaatt ttaggcaaaa atgaagtaaa
    22741 tattctcaca agaaaacgta tatcatcaaa gttttaggtg tactgacccc aaaaagttag
    22801 acaa
//
LOCUS       DAVHBD010000040        21736 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000040 DAVHBD010000000
VERSION     DAVHBD010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21736
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.040"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            512..1243
                     /locus_tag="VVK04_001615"
     CDS             512..1243
                     /locus_tag="VVK04_001615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990249.1"
                     /translation="MKILNININDFGGPENHRENFKNKFGNGKYIQEWDKLDKKETIN
                     SFISKIDEYKPDIIIIQEYDINSTECQDIFVPLMRKKGYILESVLESVLEPVQQRKRP
                     SMTVFFVKNDLKYKPISTGHDRNARAYAIQVNDLVIYGTHVPPSDNVESFWKEINNFV
                     QEFKNNKLLLIGDFNTVNFKNNKALDNLLENPIHKIHKIWSHEGCNIPGDYVLANFDI
                     NQDGIDYFATKTITDHEFGVIITTD"
     gene            1309..1722
                     /locus_tag="VVK04_001616"
     CDS             1309..1722
                     /locus_tag="VVK04_001616"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990250.1"
                     /translation="MTSILFSNSPNVLVYQIHKEKVIAKNITLDYSNSDFIFPVIDTY
                     IDSGNGFDYIFSHDVLVIPDPRSKQSIKTYSLYFNSDMIPISTQGEWIACFGIIKKEN
                     GMIVAGNIQLDQTLHLIKHFTITDSNNNRLPIQYT"
     gene            1988..2500
                     /locus_tag="VVK04_001617"
     CDS             1988..2500
                     /locus_tag="VVK04_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990251.1"
                     /translation="MEFQVRVSSEAIFYFEKLKKMYSNNSKFELTRSQILTRAFEETK
                     IITNWTSIINDTETISLEYLEYQKGYGTNVKVQISDEVEKGIRELKILLPNFTTTRSV
                     TIGVAVKFMLKGAIILNKTGKINTNKNLSTMEAIEELKQNLQDIVAPINYNVLENIMD
                     NFKNNISLIQ"
     gene            2946..3341
                     /locus_tag="VVK04_001618"
     CDS             2946..3341
                     /locus_tag="VVK04_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000409324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990252.1"
                     /translation="MEIYTYSDFLQEKTALTFEDAHKIYNELISSFDIKDPIFLDDWT
                     MLIELASEYTEIRVKSATVSKERQDKHGTLRTSAHDAFMVQLNALKNEIESTGGNTSW
                     FDKITDDRQRQGDFANYLAYIYAVSTRSS"
     gene            3415..4308
                     /locus_tag="VVK04_001619"
     CDS             3415..4308
                     /locus_tag="VVK04_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990253.1"
                     /translation="MEHQEVIDWLKYCDENNIKPWEWDFKNCYSDTLTPDSITNFLKY
                     KNAELTNPTTFRVTKLIGKYADSDKEAFYLYKLLGWQESQDSIIRGETINSYLTTFKK
                     AMELSYNYNFLYNELKLDEIKTIGKKDFPQYYINLYKNKNYEKFDIIAKNADNFKKFA
                     ELTHTIGNFIVLPHWMNTGRYNFSKDYWDLTLLSLYEWFNAFLTEDESWKKFIKNYYL
                     QPYVNSNYQPEIFWENHSFRNKELEGTEEFSIFLKKVNERIEERGKFIIKQICDKLDQ
                     KDFNFYKEIKNMETIRFSNEF"
     gene            4321..4791
                     /locus_tag="VVK04_001620"
     CDS             4321..4791
                     /locus_tag="VVK04_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990254.1"
                     /translation="MVRVYKSVRLAYEAKVWIDELIQKKERKIKELNQDNFLNTLEQT
                     LLSNHYDELNGVSFNIVLKASIGSIIEEAYRNTKHYSIAKWQNLRQKMEKDIKTVNPS
                     LETSVTPRLYLDENVLNGLDEFRYHLMKEDGATRLPRLSYIIKLVVYSYWKTQQ"
     gene            4864..6183
                     /locus_tag="VVK04_001621"
     CDS             4864..6183
                     /locus_tag="VVK04_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="otitis media-associated H10"
                     /protein_id="HEU3990255.1"
                     /translation="MFKLKKEANLKRNYFITSSRLKLLHLIIITFSILVLLGLIVSIR
                     APAFIQILCIVFGILAIYKINNKLKDFRYELDFDLIIRESLLFVLYTNHLYTSEKDNS
                     GYEEIIRSAILKYELDNQNSRIIIKALIRGDEFSKKVQTLDDVLAGVLELELEEKITH
                     PNIVEYHFYYKKPDRLILSPHNHKKEIDSLDIDLGYDITYNPIKCPHILVSGGTGSGK
                     SIFISFLIIELLKRNSTLYIADPKNSDLGSLSHYLSDKYIATTPNNIARIVRLVVEQM
                     QERYQAMRDNFHYGSNFADHGFKPVWLIFDEMGAFQASATDKKSKEVITEAMDGIKQI
                     ILLGRQAGVFILISAQQMRAETLNTDLRDNLGLRIALGANSIEGYRMVFGTATPDKFK
                     SIEEKGAGYLYMQGSGKEKAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            6279..6593
                     /locus_tag="VVK04_001622"
     CDS             6279..6593
                     /locus_tag="VVK04_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990256.1"
                     /translation="MKINDFLKPELLGNKFVAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQIKVNTLSPTATPQLLSDKKTCPVKLSNLTVGQFNGNLWFSCNDVVPI
                     SK"
     gene            6610..7338
                     /locus_tag="VVK04_001623"
     CDS             6610..7338
                     /locus_tag="VVK04_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU3990257.1"
                     /translation="MAKLFAISDIHGHLDEFISALSKVDLSDKNNRLILIGDYIDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETETQIFVHAGVDEEA
                     GKLWKDLTSSEMFTNKFPTTTGGFFKDIISGHIASWEVAKDKTYQGKIYFDGKNHYFI
                     DGDVYHSKTIPVICYDTVTKSYQY"
     gene            7413..8186
                     /locus_tag="VVK04_001624"
     CDS             7413..8186
                     /locus_tag="VVK04_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU3990258.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDRIIQTHNIKRVIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIEVINLIGNHDAYYLLGDQAPFSIQNLEVFFAV
                     QGLLQDLKLQVTYQLDDYLVSHAGFNQIFDPQKWHFSPYTKEHEEELDILAYTIGPMR
                     GGEALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNIIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGRLEIISTDWATDQTLKQLPKPQI"
     gene            8358..9152
                     /locus_tag="VVK04_001625"
                     /pseudo
     CDS             8358..9152
                     /locus_tag="VVK04_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269869.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
     gene            9160..9429
                     /locus_tag="VVK04_001626"
     CDS             9160..9429
                     /locus_tag="VVK04_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU3990259.1"
                     /translation="MQVILPTEQVQEIQSMITNLLQNEISHFKEDLGLDSPYLNKGQT
                     CKYLGISNNTLDGWIQKGLPVIKIGKTVRFNKNEIDKWLCRKAML"
     gene            9471..10637
                     /locus_tag="VVK04_001627"
     CDS             9471..10637
                     /locus_tag="VVK04_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014619928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU3990260.1"
                     /translation="MTVTKTNSNTYNLKVYIPKEIRPKMGIKGNHFVKRYKTRKEAKE
                     AELEILTKIHQLENGEDILLSKTNDILFSEFFNNIWWDSYKAGQTTSTTKPPTQVTID
                     NTKTVFRKHILPMFGNYSINFLNQNKQVVLNLMTAKAEEYANFKVIRSYVNSIFDWAE
                     ELEYIESNRLSKSIKRIKASKKIKLEEAKDEEDLENDKLSLKDYVLFFTAFILSDRKS
                     ESYALHWKNIDLANAQIDLRHALDKYKNVKSTKGNKKTIFSIPSYLVSLLSEWKKQQK
                     YELAKFGIMQTSDQLVFTYIDTKGNVNSPLHVDYLNNKMNSVKRRHPKLKHATPHKLR
                     HTGATLAKKAGMSLEAISEALTHSDTVTTKTYVNTSNIVPLSAGQVAYQHLKNK"
     gene            complement(11028..12935)
                     /locus_tag="VVK04_001628"
     CDS             complement(11028..12935)
                     /locus_tag="VVK04_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU3990261.1"
                     /translation="MTNESYVVGTVREIKGTNVVIRLFDNSSQMTYFFNGKRYSGIMI
                     GSYIGIKRGHYTIVVKIEKEYAQDVLRDTTVQEFSKDRFFRELEAKVIGSFVREKYIS
                     GMVAFPQIFNDVILLPNEQITSIISGESLGDNRLPSNPNSYFTIGEIWPEGIPYKVNW
                     TTIFNTHIAIFGNTGSGKSNTLARLYSNLFDLNKKNILTFGKSKFVVLDFNGEYVGHR
                     VLTDNKKVYNLNTQNSGGDKIIVPANKFWDKEMLSILFGATAQTQQPFLNRLLKYYFS
                     KNNFEENVLEYFYRAFKTVYTSTSKESLDLLKYALDVLEINHESFSTWIDFSAFNPYN
                     SNGYYSMQELSGWKANNNRWYWNADENMEALEQEIGNIKQRISIFMTLESKEKIKNPI
                     IQLRLAAYFQMIFDLSRHTIQYDHISPLIHRIEARSSDFDKVLQIEMLPENDSQELFV
                     DGNVNIVSLKNINKDIKMLLPMLIAKISYDIHRARFEQDTIFNLIIDEAHNILSENST
                     IESEKWKDYRLDVFEEIVKEGRKFGYYLTIASQRPSDISPTIVSQIHNYFIHRLVNDN
                     DLKLLDRTMTSLDYISKSSIPNLSAGQTIITGVSFDLPVIVKITQLPREESPNSSNSE
                     LLKIWKVKNYK"
     gene            complement(12932..14107)
                     /locus_tag="VVK04_001629"
     CDS             complement(12932..14107)
                     /locus_tag="VVK04_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEU3990262.1"
                     /translation="MNSDQFLKDIQGKNVNFLIGSGASSGLIPTLWIKPIEKSFEELL
                     TSKNYDENQRKVLYFIWFELWIRKTKIFDFNASNKVHNQYKRFVQNLIDFLNNEGFDK
                     PKRVNIFTSNYDTLFEMIFDKLSKENRLTYFNDGSRGFFKKFVSTENYHLKISHSGMS
                     DSFQREIPTINLLKIHGSVTWINSNNEIEVNLENKIFEKLCNSSDKIINLITKFNDNN
                     VSTEDNLLDPKKYEETLLFGSLTEEKLSEELFRIFEKFSDEVESFYLLYKTFPVVNPT
                     KEKFSDTVFQQHYYQLLRMLSFELEKNDSVLIVFGFSFSDEHILEIVRRSIVNPKLKI
                     YVIAFNEGAKKQIKEKLGNLGGNIIEYLPSISSPDGNEVQGNFSYLNSLFDAKGSDK"
     gene            complement(14122..15342)
                     /locus_tag="VVK04_001630"
     CDS             complement(14122..15342)
                     /locus_tag="VVK04_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU3990263.1"
                     /translation="MQFIPYDDELEVINTIHKYNSNDYTVIRLTQTMLNKNIIDANGF
                     LRKLLLDNDLLDFKNLTSKVYLTANLVLADQKHEVKISFYKANKRGDERFWIYGLGEF
                     IRSSQINVNDMIYITVDNQKILTLFNVTRSIPRSRTIIQIFGQDKVEASLNRLIPQMK
                     AIAKQGFHRNSKGAGEIAPKDAGDTLESLLGIKVNNSQEADFEGIIELKSKSSKTLDT
                     LFTLRPNFEGTPVADFEPNDRSRVSAFARLYGYDSDKHLGYKSLYITIGAEENPQNNQ
                     GFYLEVNDRDNIVELRKQENKKSILVAFWKFEALEEELHKKHPATLWVEVESKMDGEL
                     GYFKYVEAELTRSPQFMTFLSLIKSGAITYDWRGYTTPLGKYAGKNHGNAWRIKKKKR
                     SLLFGSTEKIKLED"
     gene            complement(15342..15803)
                     /locus_tag="VVK04_001631"
     CDS             complement(15342..15803)
                     /locus_tag="VVK04_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU3990264.1"
                     /translation="MERYVKENIERLLYSSEISQSELAKQTGLSRQTINKLLSPNTNY
                     SPKLSTLVLIANALSINFPELLIRTDKISASKEFFSNSVEEYQNILIQNVKLYLRRWN
                     QFSLSTSDGVRESTISNLVNGKYSDIYFSTIESLADEMEVSLADLFKRGEN"
     gene            15988..17538
                     /locus_tag="VVK04_001632"
     CDS             15988..17538
                     /locus_tag="VVK04_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEU3990265.1"
                     /translation="MPYAIDLFCGAGGFSEGIIQAGFDIIFSSDKSTMVKETYTNRHQ
                     QLGLIDGVDTHFELADIKELTSDKIFQSINSLKYGNIFEKGTVDVIFGGPPCQGFSRL
                     GKRDSKDPRNMLFHEYLRIIKDIMPRYVVMENVTGILDMQMLDFPSVLDNRVYKGQNL
                     VQSILRYELDELGYTLLDVQVLNAANFGIPQQRNRVVFLAYRNDVAPIKYPESDNDIP
                     NVTVYDALGNLYDGEFSYETNYSIQSRLGRTPNTDEQPIAADNPLNMEISKHDDIVTQ
                     RFSLYQQGENRAKAVNRIQLEKVELKRDYPNLFIDSLFQLNGKANQPIILKQLKNQDL
                     LQESFKSEKWLQFTNRQLGLLSMNDKNDSTKKNILKSLALRLKTSFEEAELFWNEVKN
                     HLNLEITENKFLKMLKDGDLTPAATEAIFTKKSIRVRLNQDTVSPTMVTLPDDYIHPF
                     FNRVLTVREMARLQSFDDSFEFLGKRTTGGDKRAKEIPQFTQVGNAVPPLLAKAIAEQ
                     VMIAINQQ"
     gene            complement(17787..17981)
                     /locus_tag="VVK04_001633"
     CDS             complement(17787..17981)
                     /locus_tag="VVK04_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990266.1"
                     /translation="MFIFKSSMDKDFDQICEYILKLKRAELFLHGIKQQDKTKARLYH
                     AMLEYYDANHKKVRHMRILK"
     gene            complement(17962..18294)
                     /locus_tag="VVK04_001634"
     CDS             complement(17962..18294)
                     /locus_tag="VVK04_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990267.1"
                     /translation="MRIKSVLKQVFLTEEENKKLNDCMRKENIRNFSEFARQKLIRTD
                     LNIQKVSFEGLVPLTEELEQVGKNINSIARLATVVGRISYENKMDMSILMQKIVDVME
                     KKDVYFQK"
     gene            complement(18654..19493)
                     /locus_tag="VVK04_001635"
     CDS             complement(18654..19493)
                     /locus_tag="VVK04_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001014724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU3990268.1"
                     /translation="MNGVQWIKITTDIFDDEKIQLIESMPEGDTLIVIWFKILVLAGK
                     QNNSGILSLGNKVYYTEEMLSTVFRRKATSVKLALSMFEEFGMIEIIDGAITIPKWEK
                     HQNIDGLEKIRKQTRERVARHRQKQKVLITGEPQLVLDCNVTVTAENDNVTQEIKNKS
                     KNKKEIENILDNSSRKPETYIPPKYYSLLESISYKYNDRFLYPNNYTLTHAQKMKIGE
                     YLASGYVTSDEVISMIERIPEDATSPLAYLFKSMENLKQERMLECKAIAHENARKKYM
                     INE"
     gene            complement(19502..19783)
                     /locus_tag="VVK04_001636"
     CDS             complement(19502..19783)
                     /locus_tag="VVK04_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU3990269.1"
                     /translation="MSETTLVVQLPKELEKQLRAHYDEMISNAVARVFEDKELYKPMV
                     RMSGLSRWLDVSTTTIQKWTKEGMPTMVIDGVTLYDKRVVTRWLKQYER"
     gene            19913..20431
                     /locus_tag="VVK04_001637"
     CDS             19913..20431
                     /locus_tag="VVK04_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3990270.1"
                     /translation="MTNHITKLIENSGKKLTEISEATNIAYPTLSGYNQGIRKPKKDN
                     AEKLAKYFNVSVAYIMGLDSNPHAPSNLKIVTDSFKTSKIGSVTPFKSDMEKLKKSIE
                     FGERALTLPLDDSFSDEFRHIFSEYLAEKNKRLMSEFIDYMNHQNKDSKVWQSWIKTD
                     EYAIRQEDRKNR"
     gene            20483..21637
                     /locus_tag="VVK04_001638"
     CDS             20483..21637
                     /locus_tag="VVK04_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU3990271.1"
                     /translation="MSIHKYKTKKGILYYVSFYIGLDAYGKKKRHLKRGFKTKKEAKL
                     YEARLEAGVVAPTVNTDKPNPKVTYKELYQEWFKAYVGTVEETTSSQTKNIYRIHILP
                     IFGGKFIDQISSLDCQNFITQKSQTFKNIKQIKSYTSKIFDFAINMNYIDRNPMKNVI
                     MPKIKKTRSDNFWSLEELHHFLDIVKETEPFKHFALFRLLAFSGLRKGELYALKWDDI
                     NFDSNLLNIDKSLGRIDGKAIEKSTKNESSVRTIYLDDETIDIIKQWRNFYLKEQSQF
                     PLTKLNISNEYMFYYISSNDKIEPLHADYINNVLNRIIKKHKLKPIIPHGFRHTHATL
                     MSEIGIDPSNTSKRLGHASSQMTLDVYTHTTKTGEKNSIDKFADYLNKAK"
BASE COUNT         7846 a         3552 c         3155 g         7183 t
ORIGIN      
        1 gctaacctaa caactaagct ctttcgaaca cgtttaatta agctattttt aactactaaa
       61 atctcagaaa ttttcaacta attttaaata attttatcta aatagggcaa attattctac
      121 aaaataaaca aatatgagtc aggtatatca acaatttggc ctatagcaca aaaaatcaat
      181 gactaaatca ataaaccaag cgtaccatct ctactttcaa aaaagtaaag atggtacgtt
      241 ttatataagt agtaaattaa acaccaaaat gctaactacc ttctactaca ttgttggaat
      301 agaaagatta aaatattcct tttattttcc ccaataatta ggttgacaaa tatctagttt
      361 cttggtaaaa ttgaattaca taatgtattt tttagattac atgtgtatca ttacctaaca
      421 aatcattatt tacttaagaa gttcgtgttt attatgcctc cttaacacat tcaactattg
      481 aaaaagctaa aattaaaaag gaaatcagaa tatgaaaata ctaaatatta atattaatga
      541 ctttggtggc cccgaaaacc atcgtgaaaa ttttaaaaac aaatttggaa atggcaaata
      601 tattcaagaa tgggacaagc tggataaaaa ggaaacaata aattctttta tcagtaaaat
      661 tgatgaatac aaacctgata ttattatcat acaagaatat gatataaatt ctacagaatg
      721 tcaagatatt tttgtacccc tgatgcgtaa gaaaggttat attctagaat cagtactaga
      781 atcagtacta gaaccagtac aacaaagaaa acgtccatct atgacagttt tctttgttaa
      841 aaatgatcta aaatataaac ctatttcaac aggccatgat cgtaatgcca gagcatatgc
      901 aatacaagta aatgatttag taatttacgg tacacatgtt ccaccaagtg acaatgttga
      961 gagtttctgg aaggaaatca ataattttgt acaagaattc aagaacaaca agttgttgct
     1021 cattggagat tttaataccg tgaacttcaa gaataataaa gcactagata atttattaga
     1081 aaatcctatc cataaaatcc ataaaatttg gtctcatgaa ggatgtaata ttccaggaga
     1141 ttatgtattg gctaattttg atatcaatca agatgggatt gattattttg ctaccaaaac
     1201 tattactgat catgaattcg gtgtgattat tacaacagac taggctaatt tcttattaca
     1261 attaagtaaa taagctgaat gatattctag aattaaaaag gagaacttat gacatcaata
     1321 ttattttcta actcccctaa tgttttggtc taccaaattc acaaagagaa ggtaatcgcg
     1381 aaaaatataa ctttagatta ttcaaattcc gattttatct tcccagtcat agatacttat
     1441 attgattcag gaaatggttt tgattatatt tttagccacg atgttttagt tatacctgat
     1501 cctcgctcaa aacaaagcat taagacatac tcgctctatt ttaacagtga tatgattcca
     1561 atttctacac aaggagaatg gatagcttgt tttggcatta taaaaaaaga aaatggcatg
     1621 attgttgctg gaaatattca actcgatcaa acgttacatt taataaaaca ttttacaata
     1681 acagattcta acaataatcg tttacctata caatacacat agagaaaagc aaaagttaac
     1741 catattactt gaggtctttg ataaacattt aactttttta ggtacttgta gaataaaata
     1801 aaatctggaa aagtcaaatc aatttctagc aatattttag aagtcacagt gtactattct
     1861 agaactaatc cactatagaa actgatttgt ttatcgataa tattcattat cttttgtact
     1921 ttttcctaaa ataaatccat ttttaattat aataaactat acaattacta taaaggagaa
     1981 ttcagaagtg gaatttcaag ttagagtatc aagtgaagct attttttatt ttgaaaaatt
     2041 gaaaaaaatg tattcaaata attctaaatt tgaactcacg cgtagtcaaa tactcactag
     2101 agctttcgaa gaaactaaaa ttattacaaa ttggacatct atcattaatg atacagaaac
     2161 aatatcacta gaatatttag aatatcaaaa aggttacgga acaaatgtta aagtacaaat
     2221 aagtgatgag gttgagaagg gaattagaga attaaaaata ctattaccaa attttacaac
     2281 tacgagaagt gtaaccatcg gcgttgctgt taaatttatg ttaaaaggag ctattatatt
     2341 aaataaaact ggaaagataa atacaaataa aaatttgtct accatggaag caattgagga
     2401 attaaaacaa aacttgcaag atatagttgc tcccataaat tataatgtac tagaaaacat
     2461 aatggacaat tttaaaaata acatctcatt gatacaatag aggagacttc tcctccttta
     2521 ttattttatt tcaatatgat tttggattat ttttttataa aatagttgac atttactttc
     2581 ggattatata taatatattt agattacaaa atataaagga gttatgaata tgttcgacca
     2641 agaaactttg gatctcttct atgaggaatt agaagactat tatgacgaag atgaacaagg
     2701 agagattttt gacggattag atgactatta ggattgtttc cttctactac aaaattacgc
     2761 ttactcggta tcttgtatgc tatattatat agctttatga attgttttaa ctgattaaaa
     2821 ggtgcaaaaa aataaaaact atggctaagt tggaatatta aaaatccttg attttatttt
     2881 tatataggat tataatcaaa atatagttgt ggttatacaa aaataattat ttacggaggc
     2941 cctttatgga aatttacact tattctgatt ttcttcaaga aaaaactgct ttgacttttg
     3001 aagatgcaca taaaatctat aatgaactaa ttagttcatt tgacataaaa gatccaattt
     3061 tcctcgatga ctggacaatg ttgattgagt tagcttcaga gtatactgaa attcgtgtca
     3121 aatctgcaac agtgtcaaaa gaaagacaag acaagcatgg gactcttaga acctctgctc
     3181 atgatgcttt catggtacaa ttgaatgcac taaaaaacga aatcgaatct acaggaggaa
     3241 atactagctg gtttgacaaa attacggatg accgacaacg gcaaggagat tttgcaaact
     3301 atttagccta catttacgct gtaagcacta gatcatcata aaataaaaat actcttcaaa
     3361 cagttgctta agattatcaa aacttaactt taataagacc gaaaggaaaa gcttatggaa
     3421 catcaagaag ttattgattg gttgaaatat tgtgatgaaa ataatatcaa accatgggaa
     3481 tgggatttta aaaattgtta ttctgatacg ctaacaccag atagtattac aaatttttta
     3541 aaatataaaa acgctgaact tacaaatcca actacttttc gagttactaa actaattgga
     3601 aagtatgctg acagtgataa ggaagcattc tatctatata aacttttggg atggcaagag
     3661 tcacaagata gtatcattag aggagaaact ataaattctt atttaacgac gttcaagaaa
     3721 gctatggaac ttagttataa ctataatttt ttgtataacg aattaaaatt agacgaaatc
     3781 aaaacaatag gaaagaaaga tttccctcaa tattacataa atctatataa aaataaaaat
     3841 tatgaaaaat ttgatattat cgctaaaaat gcagataatt ttaaaaaatt tgctgaacta
     3901 actcacacaa ttgggaactt tattgtatta cctcattgga tgaatactgg tcgatataat
     3961 ttttcaaaag attactggga tcttacttta ctttctttat atgaatggtt taatgctttc
     4021 ttaactgaag atgaatcttg gaaaaaattt attaaaaact attacttaca accatatgta
     4081 aatagtaatt atcagcctga aattttttgg gaaaatcatt cctttagaaa caaagagcta
     4141 gaaggtacgg aggaattctc aattttcctc aaaaaagtca atgagcgaat tgaagaacgt
     4201 ggtaaattta tcattaaaca aatctgtgat aagttagatc aaaaagattt caatttctat
     4261 aaggaaatta aaaatatgga gacaataaga ttttctaatg aattttaaaa aggaggattt
     4321 gtggtcagag tatataaaag tgttcgtctt gcatacgaag ccaaagtatg gatagatgag
     4381 cttattcaaa aaaaagagcg taaaatcaaa gaactaaatc aggataattt tctaaatacc
     4441 ctagaacaaa cacttctatc aaatcattac gatgaattaa atggtgtttc ttttaatatc
     4501 gttttaaaag cttctatcgg aagtattatt gaagaagcat atagaaatac aaaacattac
     4561 tccattgcta aatggcagaa tttgcgtcaa aaaatggaaa aagatatcaa aactgtcaat
     4621 cctagtctag aaacatcggt aacccctaga ctctatttag atgaaaatgt tctaaatggt
     4681 cttgatgaat ttcgatatca tttaatgaaa gaagatggtg ctactagatt accaaggctt
     4741 agttacatca ttaaacttgt tgtttattcc tattggaaga cacaacaata acctaagcaa
     4801 aacctgctta ggtcccttat aaaaacaaat gtatatgtgt tatactacat aagaggactt
     4861 tttatgttta aattaaaaaa agaagctaac ttaaaaagaa attattttat tacaagttca
     4921 cgtttaaaat tattacatct gataataatt accttttcta tccttgtttt attaggttta
     4981 atagtaagta ttagagctcc tgcttttatt caaatcttat gtattgtctt tggtattcta
     5041 gcaatctata aaataaataa taaattaaaa gattttagat acgaactaga ttttgattta
     5101 attatcaggg aaagcttact atttgtttta tatacaaatc atctctacac ttcggaaaag
     5161 gataattcag gttacgaaga aattattaga agtgcgattt taaaatatga attagataat
     5221 caaaacagtc gtattatcat taaagcgctt atcagaggtg acgaatttag taaaaaggtt
     5281 cagacacttg atgatgtatt agctggagtt ctagaacttg aactagaaga aaaaattact
     5341 catcctaata ttgttgaata tcacttttat tacaagaaac ctgatagact aatattatca
     5401 ccccataatc ataaaaaaga gatagatagt cttgatatag acttaggata tgatataact
     5461 tataatccta taaaatgtcc tcatatttta gtttcaggtg gtacaggtag tggaaaatct
     5521 atatttatat ctttcttaat tattgaactt cttaaaagaa attcaacact atatattgca
     5581 gatcctaaga acagtgattt aggtagttta tctcattatt taagtgataa atatatagct
     5641 acaactccca ataatattgc tcgtattgta cgtttggtag ttgaacaaat gcaggaacga
     5701 tatcaagcca tgcgtgataa ctttcattac ggttcaaatt ttgccgatca tggatttaaa
     5761 ccagtatggc ttatatttga tgaaatggga gcatttcaag cttcggcaac agataaaaaa
     5821 tctaaagaag ttatcactga agcaatggac ggtattaaac aaattattct actagggcga
     5881 caagcaggag tatttatcct tatatctgct caacaaatga gagctgaaac tctcaacact
     5941 gatcttagag ataatttagg actaagaata gctttaggag caaactcaat agagggatac
     6001 cgcatggtat ttggcacggc tacacctgat aagtttaaat ctattgaaga aaagggagca
     6061 ggatatcttt atatgcaggg ctcaggaaaa gaaaaagctc aatattggga aagcccctat
     6121 cttgatacaa cacaattcga ttttataaaa gaactacaat tatacgtaac aaagtcaaaa
     6181 taatttcaat agatattttt gcttaaattc aatagatttt cagcaaaaat atctattcct
     6241 catcgcttaa gcgatgacaa aaagaaacga ggtattatat gaaaattaac gattttctta
     6301 aaccagaatt attaggaaat aaattcgtgg cagtaaaagg atatacagaa gttttggaca
     6361 gagaaacaaa taaacctgta gcactacgtc ttaatgtttc aattcaagat gaggattctg
     6421 atttctttat ggaaatgatc cagataaaag ttaatacgtt atctcctacg gctactcctc
     6481 aattattatc agataaaaaa acatgccccg ttaaattatc taatttaaca gttggacaat
     6541 ttaacggaaa tttatggttt tcttgtaacg atgtagtccc tatttctaaa taattcggtg
     6601 atactattta tggctaaact ttttgcaata tctgatatac acggtcacct agatgagttc
     6661 ataagtgctc tcagtaaagt agacctatct gataaaaaca atcgtcttat tctaatcgga
     6721 gactatattg acaatggact tcaatctttt caagtcattt ccaaaataat cgaacttgag
     6781 gaggtttatc ctaatcaaat tattactctt ctaggaaacc atgaagaatg gttttatgat
     6841 tggttgattt tagataaacc tactgcttca gcatttccag aaacaataaa aagcttcttc
     6901 tctccagagg aattgaacta tatttttaaa tcgaatgcta acaactttga aacaggtgtt
     6961 agaaatgaaa ttaaaaataa tatcaaattc aacccattta taaactggtt taaaaaacga
     7021 tatagggata aacgctatta tgaaactgaa acccaaattt ttgttcatgc tggtgttgat
     7081 gaagaagcgg gcaagctttg gaaagaccta acgagttcag agatgtttac aaataaattt
     7141 cctactacca ctggtggatt ttttaaagat attatttctg gtcatattgc ttcttgggaa
     7201 gtagctaaag ataaaactta tcaaggtaag atttactttg atggtaaaaa ccattacttc
     7261 attgacggcg atgtgtatca tagtaaaaca atacctgtta tctgctatga tacagttaca
     7321 aaatcctatc aatattaaat aacatcctaa aaaaattggt ataatttaat tctattctta
     7381 gactaatatc aaaaataaag aggggaatct atatgaagac attattaatt ggcgacttac
     7441 atttaaaatc tcaactaatt ttacctattg tggacaggat tatccaaaca cataatatta
     7501 aaagagtcat ttttcttggt gattatgttg atttacatgg acaaactaac aatatccaac
     7561 tatatgccaa agatctcact tttttatact cttggaaaat agataaagag caaaacggaa
     7621 tagaggtaat taatcttata ggtaatcatg atgcttatta tttactggga gatcaagctc
     7681 ctttctcaat tcaaaattta gaagtgtttt tcgcagttca aggattgttg caggatttaa
     7741 aattacaagt gacttatcaa ctagatgatt atttagtcag tcacgctggt ttcaatcaaa
     7801 tatttgatcc tcaaaaatgg catttttccc cctataccaa agagcatgaa gaagaattag
     7861 atattctagc ttatacaata ggaccaatgc gtggtgggga agctcttggg ggttctcctt
     7921 tatgggcaca ttttagagaa ttagaactgc ttcccaacca agactttcct aaacaaattg
     7981 ttggacatac tccaaaagaa tctattgata tttctaaaaa tattattggt atagatactt
     8041 tttcattata tattgacaaa gataataaat atcaatttat tggtaacgga gatttgctag
     8101 tttatgatca aggacgtctt gaaatcattt caactgactg ggctacagac caaacattaa
     8161 aacaattacc taaacctcaa atttaactac tacttctcat catgtgacta agcgaaactg
     8221 ccgactagaa gtcggcaagc tggaagcgtg tttagcagag cgatgcttag aaacacatga
     8281 tagaagtgtg gagaagcttt gcttctccta gtttatttat tatataagca aacattacga
     8341 gaaaaggaga tgattttgtg agttacaatc gcaaaattat ccgaacttct tcgtaccttg
     8401 aaatatggga atacgaatct ccaatttttt caaatgatac tactcaaatt gatgaagacc
     8461 acatttcact aaaagaaaag aagaaacgta gaacttttga agaactcaca actgctgaac
     8521 aagatgaacg aataaaaaga atttctaaca ctcgtaaaaa ttctaaatgg aaacttcaac
     8581 gcctaataga tacaaatttt gatgacagaa ctagtttcct tacccttaca actaaagaaa
     8641 atatacaaaa cagatatgag tttaatttaa tttttgataa atttattaaa cgtttaaact
     8701 attacatata ccattccaaa aaaagactta ttaaatatat cgcagtatta gaacgacaaa
     8761 aaaggggagc gtggcatgca cacattctcc ttttttcatt tccttttatc cctcataaag
     8821 aattactgac aatttggggg ttaggtgcag ttcggataaa caaactaaat aagttagatg
     8881 attcttctaa tgctggtcgt tatgttgcaa aatatatgga aaaaggcata ggataggaat
     8941 tattagagag tctaggaaag aaggcttttt attcttctcg taatttacaa aagcctaaag
     9001 aaataaaatt atttacaagc gaatccttag ataaccttgt taagaatgaa gatatcctat
     9061 atgaaagcaa ctatattagc aaagtatttc gaaaaggaca cttaattgac aataaagtaa
     9121 aatacaaaaa aataaagtta agtaaggagt aaggaaaaaa tgcaagttat tctaccaaca
     9181 gaacaagttc aagaaataca gtcgatgatt actaatctct tgcaaaatga aatttctcat
     9241 ttcaaagaag atttaggttt agatagtcct taccttaaca aggggcaaac ttgcaaatat
     9301 ctagggatat ctaacaatac attagatggc tggatacaaa aggggctacc cgttattaaa
     9361 attggtaaga ctgtccgttt caataaaaat gagattgata aatggctttg tagaaaagct
     9421 atgctataat atctctaatg atatatcctg actcgtaaaa ggagaacatc atgacagtta
     9481 caaaaacaaa tagtaacact tacaatctta aagtgtatat acctaaagaa atccgaccta
     9541 aaatggggat taaaggaaat cactttgtta aacgctataa aacaagaaag gaggccaaag
     9601 aagctgaact agaaatttta actaagatac atcaacttga aaatggtgag gatatcctac
     9661 tttctaaaac taacgatatt ctattctctg agttctttaa taatatttgg tgggattcat
     9721 acaaagctgg tcaaacaact tcaacaacta aacccccaac acaagttact attgataata
     9781 ctaaaactgt tttcagaaag catatcttac caatgttcgg taattattca atcaattttc
     9841 tgaatcagaa taagcaagtc gtactaaact taatgactgc taaagctgaa gagtatgcta
     9901 atttcaaggt tattcgaagc tatgtaaact caattttcga ttgggctgag gaattagagt
     9961 acatagaatc aaatcgatta tcaaaaagca taaaacgtat taaagcaagt aaaaaaataa
    10021 agctagaaga agctaaggat gaggaagatt tggagaacga caaattatca ctaaaagatt
    10081 atgtcctatt ctttacagcc tttattttga gcgatagaaa atcagaatcc tatgctctac
    10141 attggaaaaa catagacttg gcaaacgctc aaattgactt aaggcatgca cttgacaaat
    10201 ataaaaatgt gaagtcaaca aaaggaaata agaaaacgat tttttcaatt cctagttacc
    10261 ttgtatcact tctttcagaa tggaaaaaac aacagaaata tgagttagcg aaatttggta
    10321 taatgcaaac atccgatcaa ctagtcttta cctatataga tacgaaaggt aatgtaaata
    10381 gccctctaca cgttgattat ctcaataaca aaatgaactc cgtaaaaaga agacacccaa
    10441 agttaaaaca tgctacacct cataaattac gacatacagg agcgacactt gctaaaaagg
    10501 ctggaatgag cttagaagcc atttctgaag cattaactca tagcgatacc gttacaacta
    10561 aaacttatgt taatacctca aacatagttc ctttatctgc tggacaagtt gcctaccaac
    10621 atcttaaaaa caagtagggt aattttaggg caaattttag ggcaaatttt tgtagaaagt
    10681 acagaaaaaa cacccatagg gcaaaccttt gagtgctttg aaacgttgat ataatcggat
    10741 tgattaacgt ttactaaatt gtgatgcttt acgagctttc ttaagacctg gttttttcta
    10801 cattatgata tttatggtaa attatcactg aaatcaagtt cttttaagag ataaatcctc
    10861 aatttttaca tatataaccc ttttaaaaat caggaggtta tcaaagggtt atcacttttt
    10921 agttttcgga gcttatgcaa ttgagaaata acctactttt aagctattaa ctcccaaaag
    10981 taactcagtt aatttgattt taaaaccata aactatacca ccttatttta tttatagttt
    11041 ttgaccttcc atattttcag tagctcacta tttgaactat ttggagattc ttcccttgga
    11101 agttgagtaa tcttaacaat tactggtaaa tcaaaagaga cacctgtgat tattgtttgt
    11161 ccagcagata gattaggaat acttgacttt gaaatatagt ctaaagatgt cattgttcta
    11221 tctagtaatt ttaaatcatt atcatttacc aatcgatgga taaaatagtt atgaatctgt
    11281 gaaacaattg tcggagagat atcagaaggt ctttggctgg ctattgtaag ataatatcca
    11341 aatttccgcc cttcttttac aatctcttcg aaaacatcca atctatagtc tttccatttt
    11401 tcagattcaa ttgtagaatt ttccgaaaga atattgtgcg cttcgtcaat aataagatta
    11461 aatatagtat cttgctcaaa tctagctcta tgtatatcat aactaatttt agcaattagc
    11521 attggcaaca acatttttat gtctttatta atatttttta acgaaacaat atttacattc
    11581 ccatcaacaa ataactcttg agaatcattt tctggtaaca tttcaatctg aagaacttta
    11641 tcaaaatcac tggaacgtgc ctcgattcta tgaataagag gtgaaatatg gtcatactgt
    11701 atagtatgac gagacaaatc aaaaatcatc tgaaagtaag ctgccaatcg cagttgaata
    11761 ataggatttt tgattttttc ctttgactcc aacgtcataa atattgaaat ccgttgtttt
    11821 atatttccaa tttcttgttc taatgcttcc atattttcat cagcattcca ataccaccta
    11881 ttattatttg ctttccaacc agacaattct tgcatgctgt aataaccatt tgaattatac
    11941 ggattaaaag cactgaaatc aatccatgta gaaaaacttt catgatttat ttctaaaaca
    12001 tccagtgcat attttagtaa atctaaagat tcttttgatg tagaagtata aactgtttta
    12061 aaagctctat aaaaatattc taacacattc tcttcaaaat tattttttga aaagtaatac
    12121 tttaataatc tatttaaaaa aggctgttga gtttgtgcgg tcgcgccaaa taaaatggat
    12181 aacatttctt tatcccaaaa tttattagca ggcactataa ttttatcacc ccccgaattt
    12241 tgagtgttta gattatacac tttcttatta tcagtcaata ctctatgccc tacatactca
    12301 ccattaaaat caagaactac aaacttagat ttaccaaacg ttaagatatt cttcttattt
    12361 aaatcaaata gattactata aagtctagca agagtattag atttaccact tccagtatta
    12421 ccaaaaatcg caatgtgagt attaaaaatc gttgtccaat taaccttata gggaatacct
    12481 tccggccata tttctcctat agtaaaatat gaattcggat tcgaaggcaa tctattatct
    12541 cccaaacttt caccacttat tatagaggtt atttgctcat ttggtaatag aataacgtca
    12601 ttaaatattt gcggaaaagc caccattcct gatatatatt tttcacgaac aaagcttcca
    12661 attacttttg cttccaattc tctaaagaac ctgtctttag aaaactcctg aactgttgtg
    12721 tctcttagaa catcctgtgc atactctttt tcaattttta ctactatcgt ataatgacca
    12781 cgtttaattc caatatatga tccaatcata atacccgagt aacgtttccc attaaagaaa
    12841 taggtcattt gtgatgagtt atcaaataat cgaataacca catttgttcc cttaatttct
    12901 cttacagtcc ctactacata actttcattc gtcatttgtc actccccttt gcatcaaata
    12961 atgaattaag atatgaaaaa tttccttgaa cttcattgcc atctggagat gagatagacg
    13021 gaagatactc tataatattt cctcctaaat ttcccaattt ttcctttatt tgcttcttcg
    13081 caccttcatt aaaagcaata acataaatct tgagtttggg attaactatt gaacgacgta
    13141 caatctctaa gatatgttca tcagaaaacg aaaaaccaaa aacaattaaa acactatcgt
    13201 ttttttccaa ttcaaaactt agcatccgca ataactgata gtaatgttgt tgaaaaacag
    13261 tgtctgaaaa tttttccttt gtagggttta caactggaaa tgttttatat aatagataga
    13321 acgactccac ttcatcggag aatttttcaa atattctaaa taattcctca cttaatttct
    13381 cctcagtcaa gcttccaaaa agaagagttt cttcatattt ttttggatcc aataagttat
    13441 cttcagtgct cacattatta tcattaaatt tagttattaa attgataatt ttatcgctcg
    13501 aattacacag tttttcgaat attttgtttt ctaaatttac ttcaatctca ttgtttgaat
    13561 taatccaagt tacagatcca tgaattttca acaaattaat agttggaatc tcccgttgaa
    13621 aggagtcact cattccagaa tgagatatct tcaagtgata gttttccgtc gaaacaaact
    13681 ttttgaagaa cccccgacta ccatcattga agtaagttaa tctattttcc ttacttagtt
    13741 tatcaaatat catttcaaat aacgtatcat aattcgacgt aaatatatta actcttttgg
    13801 gtttatcaaa accctcatta ttaagaaaat caattaaatt ttgaacaaat cgtttatatt
    13861 gattatgaac tttattactt gcattaaaat caaaaatctt tgttttacgt atccaaagct
    13921 caaaccaaat gaaataaagg acttttcgtt gattttcgtc ataatttttt gaagtcaata
    13981 attcttcaaa agacttttct attggcttaa tccacaatgt aggaattaat cctgaagaag
    14041 ctcctgaacc tatcaaaaaa ttgacatttt ttccttgaat atcttttaaa aattggtcag
    14101 aattcatctt attactcacc ttcaatcttc aagtttaatt ttttctgtac taccaaataa
    14161 caaacttctt ttctttttct taatcctcca agcattacca tgattcttac cagcatactt
    14221 acccaacggg gtcgtatagc cacgccagtc ataggtaata gctcctgatt ttatcagaga
    14281 aagaaaagtc ataaattgcg gtgaacgtgt taattctgct tcaacgtatt tgaaataacc
    14341 taattcgcca tccattttgg attcaacttc cacccataaa gttgctgggt gttttttatg
    14401 taattcttcc tctaatgctt cgaatttcca aaaagcaacc aaaatactct tcttgttttc
    14461 ttgttttcgt agttcaacaa tattgtctct atcattaact tccagataga atccttgatt
    14521 attttgagga ttttcttctg cacctattgt aatatacaag ctcttatatc ctaaatgttt
    14581 atctgaatca taaccatata ggcgagcaaa tgctgatact ctacttctat cattcggttc
    14641 aaaatctgca acaggtgttc cttcaaaatt aggacgtaga gtaaataagg tatccaatgt
    14701 tttagaagat tttgacttta attcaataat tccttcaaaa tcagcttctt gactattatt
    14761 aactttaatt cccaaaagcg actccagagt gtccccagca tccttcggtg caatttcacc
    14821 agcacctttt gagtttctat gaaatccttg ttttgctatg gctttcatct gcggaatcaa
    14881 cctatttaat gaagcctcta ctttatcttg tccaaatatc tgtataattg tacgacttct
    14941 aggaatacta cgtgtgacat taaataaagt taatattttt tgattgtcta cagtaatgta
    15001 aatcatgtcg ttgacattga tttgagatga cctaatgaac tctcctaacc cgtatatcca
    15061 gaatctctcg tctcctcttt tattggcttt atagaaactt atttttactt cgtgtttctg
    15121 atcagccaac accagattag ctgtcaggta aacttttgaa gttaagtttt taaaatccaa
    15181 taaatcatta tctaacagca attttcttaa aaaaccgttt gcatcaataa tatttttatt
    15241 tagcatggtt tgtgtcaatc ttataacagt atagtcatta gaattgtact tgtgtattgt
    15301 attaataacc tctaactcat catcatacgg aataaattgc attagttttc tcctctctta
    15361 aataaatcag ccagtgaaac ttccatttca tctgcaagac tttctattgt tgaaaaataa
    15421 atatctgaat atttaccatt tacaagatta cttatagtag actctctaac tccatctgaa
    15481 gtactcaatg aaaattgatt ccatcttctc aaatatagct tgacattttg tataagaata
    15541 ttttgatatt cctccacaga attagaaaaa aattctttgg aagcactgat cttgtcggtt
    15601 ctaatcaaaa gttctggaaa attgattgat aaagcattag caatcaatac caatgttgaa
    15661 agtttaggac tataattagt atttggagat aataatttgt taatcgtttg cctactaagt
    15721 cctgtctgtt tagctaactc actttgcgat atttcactcg aataaagcaa tcgttcaata
    15781 ttttctttta catatcgctc cataacaact ctccaattct cattttcttt atattacaac
    15841 tttaagcaac ctaataattc attttagttt acattttgac tgttttttaa ttcttttacg
    15901 aatatacaag tagaaagtaa tccctggact tttcaaaaaa attctgatat actactaagg
    15961 tagtaaatac aaaattcgag gtaaattatg ccctatgcaa tagacttatt ctgcggtgct
    16021 ggaggattta gcgaaggaat catccaagct ggttttgata ttatcttttc tagcgataaa
    16081 agcactatgg taaaagaaac atatacaaac cgacatcaac aattaggttt aatcgatggt
    16141 gtcgacaccc actttgaact cgctgatata aaagaactga cttctgacaa aatttttcaa
    16201 tcaatcaact cattgaaata tggaaatatc tttgaaaaag gaactgtaga tgttatcttc
    16261 ggaggtcctc cctgccaagg cttcagccgt ctaggaaaac gagatagcaa agatcctaga
    16321 aatatgctct tccacgaata tttgcgtatt attaaagata tcatgccacg ttatgttgtt
    16381 atggaaaatg taactggtat tttggatatg caaatgttag atttcccaag cgtactcgat
    16441 aatagggttt acaaaggaca gaatttggtt caatctattc ttagatatga gttggacgag
    16501 ctaggataca ctttacttga tgttcaagtt ctaaatgctg caaattttgg tataccacaa
    16561 caaagaaatc gagttgtatt tttagcatac cgaaacgatg tagcccctat taaatatcca
    16621 gagagtgaca atgatatccc aaatgttact gtttatgatg ctttaggtaa tctttatgat
    16681 ggggaattta gttatgaaac aaattattcg atacaaagtc gattaggaag aactcctaac
    16741 acagatgaac aacctattgc agctgataat ccattgaata tggaaatatc gaagcatgat
    16801 gacattgtta cacaacgttt ttcattatac caacaaggtg agaacagagc caaagcagtt
    16861 aatagaatcc aattagaaaa agtagaatta aaaagggatt atccaaacct atttattgat
    16921 agtttgttcc aactaaatgg caaagctaat caacctatta ttttaaagca acttaaaaac
    16981 caagatttac tccaagaaag tttcaagtct gaaaaatggt tgcaattcac taatcgtcag
    17041 ctgggattgt tgtctatgaa tgataaaaac gattcaacta aaaaaaatat cctaaaatca
    17101 ttagcactta ggttaaaaac ctcatttgag gaagccgaac tattttggaa tgaagttaag
    17161 aatcatttaa acttagaaat aacagaaaat aagtttttaa aaatgttaaa agatggtgat
    17221 ttaactcctg ctgcaaccga agctatcttt accaaaaaga gtattcgagt tcgtcttaat
    17281 caagataccg tctcaccaac tatggtaaca ttaccggatg actatatcca cccatttttt
    17341 aatcgagttt taactgtaag agaaatggct cgtctacaat catttgatga tagttttgaa
    17401 tttcttggta agcgtacaac aggaggtgat aaacgagcaa aagaaatacc ccagtttact
    17461 caggtaggta atgctgttcc accgttactg gctaaagcaa ttgctgaaca agtaatgatc
    17521 gcaataaatc aacaataata tcattaaggg tttggggact tccccaaaat gcaaatcacc
    17581 tcaaaagtac atacactttg tgtatacaaa ctttggaggt gattttagga gtgtgtgtat
    17641 acagactctg agctcgcaaa gtcatattat gataaatctt tccttctcga taaaataatc
    17701 ccaaaaatca atttgactgt catttgtgtg tacaaatatt ttaagaagat atataaaaaa
    17761 cgctgcaaat ttttaacagc gtttccttat tttaaaattc tcatatgtct tactttttta
    17821 tggttagcat cgtagtattc cagcatcgca tgatacaaac gagccttcgt tttatcttgt
    17881 tgtttaatcc catgaagaaa taattctgct cgctttaatt tcaatatgta ttcgcatatc
    17941 tgatcaaaat ccttatccat actacttttg aaaataaaca tcttttttct ccatcacatc
    18001 aactattttt tgcatcaaaa tagacatatc cattttgttt tcatagctta ttctcccaac
    18061 tacagttgca agacgggcta tagaattgat attctttccg acttgttcca actcttctgt
    18121 taaaggaact aaaccttcaa aagaaacttt ttggatgttc aaatctgttc gtattaattt
    18181 ttgtctagca aactcagaaa aattacgaat attttccttc ctcatacaat catttaattt
    18241 tttattttct tcttccgtca aaaacacctg tttcaacaca gattttattc tcatggtcct
    18301 atcacctcgt tttcttattt agtcgtttta caagttcttt cacttgttta cttgtcttct
    18361 tttcatattc tatcatcagc tcaacgcagt agtgaaatat ccttacatta tccaaatctt
    18421 cactttgttc tgctattctt tctaactgac gtaagttatt gataattctt ctaacttgaa
    18481 atataaagtc atgataagat tcaaaatcaa attgaagata aataggcgaa ctcttaaaca
    18541 acattttcct agcataagag gaaaaattta gatggtttgt catttcaatc aagttattca
    18601 ctatttcatt ctgctcttca gtgatataac atttctttag aacagtccta tatctactca
    18661 tttatcatat acttctttcg ggcattttca tgggcaatag ctttgcactc cagcatacgt
    18721 tcctgcttta aattctccat agacttaaat aaatacgcta aaggagaagt cgcatcctca
    18781 ggaatccgtt caatcatgct aataacttca tcactagtta catacccact agccaaatac
    18841 tcgcctatct tcatcttctg agcatgtgtt aaagtgtaat tgttaggata caaaaatcta
    18901 tcattgtact tataagaaat ggattctaac aaagaataat atttgggtgg aatataagtt
    18961 tcaggctttc tagaactatt atccagtata ttctcaatct ctttcttatt cttactcttg
    19021 tttttaatct cttgcgttac attatcattt tcagccgtta ctgtaacgtt acagtctaaa
    19081 acgagttgtg gctcgcctgt aattagtact ttttgttttt gtctatgacg agcaacacgt
    19141 tccctagttt gtttcctaat cttttctagt ccatctatat tctgatgttt ctcccatttt
    19201 ggaatggtaa tagcgccatc tatgatttct atcatgccaa attcttcaaa catactgaga
    19261 gctaatttta cagatgtagc ctttcgtcta aacactgttg aaagcatctc ttctgtgtaa
    19321 taaaccttgt tccctagact taatatgcca ctattatttt gctttcctgc aagcaccaga
    19381 attttaaacc atattacaat aagagtatct ccttctggca ttgattctat tagctgaatt
    19441 ttttcatcat caaatatatc tgttgttatc ttgatccact gaacaccatt catactagta
    19501 cctatctttc atattgcttc aaccatcgtg ttactactct tttatcgtat aaagtcactc
    19561 catcaatcac catggttggc attccttctt tcgtccattt ttggattgtt gtcgtagata
    19621 catctaacca cctagacaaa cctgacatac gaaccatggg tttataaagt tctttatctt
    19681 caaatactct tgctacagca tttgaaatca tctcatcata atgggcacgt aattgcttct
    19741 ctaattcttt aggaagctgg acaactaaag tagtttccga cataaattaa cacctcattt
    19801 ctaaattaaa taagctccga aaccatttaa tttgttattc attttgaatt tttgtcgagc
    19861 ttttttattc aaaaagaata aaatgtgtta taatgataaa aaggaggttc ttatgaccaa
    19921 tcatattact aaactgatag aaaatagcgg aaaaaaattg acagaaatta gcgaagctac
    19981 aaatatagcc tatcctacac tttctggata caatcaagga atccgcaaac ctaaaaaaga
    20041 taatgctgaa aaattggcaa aatactttaa tgtttccgtc gcttacatta tgggacttga
    20101 tagcaaccca cacgctccat caaatcttaa aattgttaca gatagtttca aaacatctaa
    20161 aattggttct gtgacacctt ttaaaagcga tatggagaag ttaaagaaaa gtatcgaatt
    20221 tggcgaaagg gcattaacac taccacttga tgatagtttt tcagatgaat ttcgtcatat
    20281 attctcagaa tacctagctg agaaaaacaa acgtcttatg tctgagttta tagactatat
    20341 gaatcaccaa aataaagatt ctaaagtttg gcagagctgg attaaaacag acgaatacgc
    20401 tatccgccaa gaagatagaa aaaatagata gacactcatt tctcaattac ataagctccg
    20461 aaaacttaga tacggagaaa aaatgtctat acacaaatac aaaacaaaaa aaggaatcct
    20521 atactatgtc agcttttaca ttggcttaga tgcttatgga aagaaaaaaa ggcacttaaa
    20581 gagagggttc aaaaccaaaa aagaggcaaa attgtacgaa gctcgtttag aagctggtgt
    20641 cgttgccccc acagtaaata ccgacaaacc taaccccaaa gtcacttata aagaacttta
    20701 tcaagaatgg tttaaggcct atgttggtac cgttgaagaa acaacttctt cccaaactaa
    20761 gaatatctat cgaatacata ttctaccaat atttggcggt aaatttattg accaaatcag
    20821 ttctttagac tgtcaaaact ttattacaca aaaatctcag actttcaaaa atatcaaaca
    20881 gataaaatcc tatacctcaa aaatttttga ttttgcaatc aatatgaact acattgatcg
    20941 aaatccaatg aagaatgtta tcatgcctaa aatcaaaaaa actagatcag ataatttttg
    21001 gtctctggag gaattacatc atttccttga tatagtgaaa gaaactgagc catttaaaca
    21061 ttttgcttta tttagactgc ttgcatttag tggactacga aaaggggagt tatacgcttt
    21121 aaaatgggat gatattaact ttgacagcaa cctattgaac atagataaaa gtctaggaag
    21181 aattgacggt aaagcgattg aaaagagcac aaagaatgaa tcttcagttc gtacaatcta
    21241 tcttgatgat gagacaatcg atattattaa gcaatggaga aatttctatc tgaaagaaca
    21301 atctcagttt cctcttacaa agctgaatat tagtaacgaa tatatgttct attacatatc
    21361 aagtaatgac aaaattgaac ctttgcatgc tgattacatt aataacgtac tgaatcgaat
    21421 tattaaaaag cataaattaa aaccaattat cccacatggg tttagacata cacatgcaac
    21481 acttatgtct gaaattggaa tcgatccttc taatacatca aaacgtctcg gtcatgcaag
    21541 cagtcagatg acattagatg tctatactca caccacaaaa actggtgaga aaaactctat
    21601 tgacaaattt gcagattatc tcaataaagc aaaatagaat tatgattttt aaaattttga
    21661 agaggttatc agaaggttat cacaaagcta ttctagctca aaaatcgaca aaaaagcact
    21721 ttgcaaaatc tttgca
//
LOCUS       DAVHBD010000041        20986 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000041 DAVHBD010000000
VERSION     DAVHBD010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20986
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.041"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..551)
                     /locus_tag="VVK04_001639"
     CDS             complement(<1..551)
                     /locus_tag="VVK04_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU3990272.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTA"
     gene            793..1464
                     /gene="sdaAB"
                     /locus_tag="VVK04_001640"
     CDS             793..1464
                     /gene="sdaAB"
                     /locus_tag="VVK04_001640"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU3990273.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            1473..2345
                     /gene="sdaAA"
                     /locus_tag="VVK04_001641"
     CDS             1473..2345
                     /gene="sdaAA"
                     /locus_tag="VVK04_001641"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU3990274.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            2367..2999
                     /locus_tag="VVK04_001642"
     CDS             2367..2999
                     /locus_tag="VVK04_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU3990275.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKTKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(3260..5110)
                     /locus_tag="VVK04_001643"
     CDS             complement(3260..5110)
                     /locus_tag="VVK04_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU3990276.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(5152..6309)
                     /locus_tag="VVK04_001644"
     CDS             complement(5152..6309)
                     /locus_tag="VVK04_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU3990277.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVKSLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            6367..7533
                     /locus_tag="VVK04_001645"
     CDS             6367..7533
                     /locus_tag="VVK04_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU3990278.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLIWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            7672..7998
                     /locus_tag="VVK04_001646"
     CDS             7672..7998
                     /locus_tag="VVK04_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU3990279.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            7985..8578
                     /locus_tag="VVK04_001647"
     CDS             7985..8578
                     /locus_tag="VVK04_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU3990280.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            8571..9482
                     /locus_tag="VVK04_001648"
     CDS             8571..9482
                     /locus_tag="VVK04_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU3990281.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            9545..10609
                     /locus_tag="VVK04_001649"
     CDS             9545..10609
                     /locus_tag="VVK04_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990282.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIETPEDSEARTKIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(10681..11541)
                     /locus_tag="VVK04_001650"
     CDS             complement(10681..11541)
                     /locus_tag="VVK04_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU3990283.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEMQPILD
                     KDFKTLAQEK"
     gene            complement(11816..12802)
                     /locus_tag="VVK04_001651"
     CDS             complement(11816..12802)
                     /locus_tag="VVK04_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU3990284.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(13074..14549)
                     /locus_tag="VVK04_001652"
     CDS             complement(13074..14549)
                     /locus_tag="VVK04_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU3990285.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(14633..15556)
                     /locus_tag="VVK04_001653"
     CDS             complement(14633..15556)
                     /locus_tag="VVK04_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU3990286.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(15570..16499)
                     /locus_tag="VVK04_001654"
     CDS             complement(15570..16499)
                     /locus_tag="VVK04_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU3990287.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(16818..17168)
                     /locus_tag="VVK04_001655"
     CDS             complement(16818..17168)
                     /locus_tag="VVK04_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990288.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
     gene            complement(17594..17749)
                     /locus_tag="VVK04_001656"
                     /pseudo
     CDS             complement(17594..17749)
                     /locus_tag="VVK04_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(17934..18545)
                     /gene="rpsD"
                     /locus_tag="VVK04_001657"
     CDS             complement(17934..18545)
                     /gene="rpsD"
                     /locus_tag="VVK04_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU3990289.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(18740..19792)
                     /locus_tag="VVK04_001658"
     CDS             complement(18740..19792)
                     /locus_tag="VVK04_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU3990290.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(19789..20487)
                     /locus_tag="VVK04_001659"
     CDS             complement(19789..20487)
                     /locus_tag="VVK04_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3990291.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(20654..>20986)
                     /locus_tag="VVK04_001660"
     CDS             complement(20654..>20986)
                     /locus_tag="VVK04_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU3990292.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT         6184 a         4550 c         3938 g         6314 t
ORIGIN      
        1 gctgtccatg aaccgtaacg tcctgcaacg taggcatctg ctacacgttc ttggttttca
       61 gctgagtagt caccgttcag gtatgaatct gttaattggt aacgtccgat ataacgtcca
      121 tttgtagctg tatagctacc acctgattct ttttgagcga tccattcttt ggcttctgct
      181 tcagatccgc ttacagttga aacaactgtt tcacttacta ctggagtttc tgccactgga
      241 gctgaaacag tttcatcttg agcggctggt gccgcataag tagctggcgc tggtgttgca
      301 acaggcgcta cagggccatc gataaccaac tcttgatcaa cataaatcaa atgaatgtta
      361 tcaatgtggt tgttttctgc caatttttca actgttgtgt tgtgagtttc agcgatttct
      421 gaaagtgtat caccttcttt aacagtgtaa gttgatgatt cttgagcaga tacaaatgat
      481 ggagcaaata ctgcaaacaa ggcagctact cctgcaagag ttgctttaat ctttttagtt
      541 attgatttca tattcgaaaa ttctccttct ttctatagtt ctatcatacc ctttaaatat
      601 taccgtttct tgacactttt atgtagaaat attacaaaat tattttttat ttccctaaat
      661 aaggtgtttt ttgtcataaa agatactatt tttatgctat ttgaggtatt agaaaggttt
      721 tcatccacaa ttaaagccaa gcccctcatt ctttgatata atagagataa gaatttttat
      781 aaggggaaac tgatgaaatc acttcgtttt caatctgtct ttgatatcat cggaccagtt
      841 atgattggcc catctagtag ccataccgct ggtgctgttc gtattgggaa gattgtctct
      901 tccatttttg atgatactcc gacagaagtt gaattccaac tttttaactc atttgccaag
      961 acctatcgtg gtcacggaac agacctagcc cttgttgcag gtattttagg aatggataca
     1021 gatgatcctg aaattccaaa tagtctggaa attgcccaca agcgtggtat caagattgtc
     1081 tggaccattc agaaagacag caatgcccct caccctaaca ccactaaaat tactgttaaa
     1141 aatgcccaca agaccatcag cgtgactggt atttctatcg gtggaggaaa tattcaggta
     1201 accgaactca atggttttgc cgtctctctc aatatgaata caccgactat catcatcgtt
     1261 catcaagata ttccaggtat gattgccctt gttacagagg cgctttcccg ctatggtatc
     1321 aatatcgccc agatgaatgt cactcgtgaa aaagctggtg aaaaagccat tatgattatc
     1381 gaagttgaca gtcgcaactg tgatgaggct atcgaagaaa ttcgaaaaat ccctcatctc
     1441 cacaatgtca atttctttaa ataggaggaa gcatgtttta ttctatcaaa gaattggtcg
     1501 agcaagcaga tctggacttt caaggaaatg tcgcagaact catgattaca acagagtttg
     1561 aattgaccgg tcgcgaacgt gaagaagtct tccttctcat ggaacgcaat ctggaagtta
     1621 tgaaagcctc tgtccaactt ggcctcaatg aaaataaatc tcgtagtggc ctgacaggtg
     1681 gagatgctgc caaattggat cactacatcg aaaacggaaa aactctgtca gattatacga
     1741 ttctctcggc tgcccgaaat gccatcgcag tcaatgaaca caatgccaaa atgggcttgg
     1801 tctgtgccac tccaaccgct ggaagtgctg gctgtctgcc atccgttctc actgctgcta
     1861 ttgaaaaatt agacctcagc cacgagcaac aattggattt cctctttgct gctggtgcct
     1921 ttggactagt catcgcaaac aatgcctcca tctcaggtgc tgagggtggg tgtcaagctg
     1981 aagttggttc agcctctgct atgagtgctg ccgccttgac tctggctgca ggtggaacac
     2041 cttatcaggc cagtcaagct attgcctttg tcattaaaaa tatgctaggc ctcatctgtg
     2101 accctgttgc aggtttggtc gaagttccct gtgtcaaacg taatgccatg ggagctagct
     2161 ttgctttcat cgcagcagac atggccttgg caggtatcga atctaaaatc cctgtggatg
     2221 aagtgatcga tgccatgtac caagtaggag caagcatgcc aactgccttt cgtgaaacag
     2281 ctgaaggtgg actcgctacc acccctactg gtcgtcgcct ccaaaaagaa attttcggag
     2341 aataagctta tcaaatagga gaaaccatga cctctatcac agcgattttt ttcgatttgg
     2401 atggaaccct cgttgatagt tctatcggga ttcacaatgc ctttacctat acctttaaag
     2461 agctgggggt gcctagccct gatgccaaaa ctattcgtgg ttttatggga ccacctctcg
     2521 aaagtagttt tgcgacctgc ctgtccaaag accaaatttc tgaagccgtg cagatatatc
     2581 gttcttacta taagacaaaa ggcatctatg aagctcaact ctttcctcag attatagact
     2641 tgcttgagga gttatcgagc agttatccac tctacatcac cacgacaaag aatacatcta
     2701 ctgctcaaga catggcaaaa aacttggaaa tccatcattt ctttgatggc atttatggtt
     2761 ctagccctga agcaccccat aaggcagatg tcattcacca agccttgcag acacatcaac
     2821 tagcaccaga acaagccatc atcatcggag ataccaagtt tgatatgctg ggagctcgag
     2881 aaacaggtat tcagaaattg gccatcactt ggggatttgg agagcaagca gatctactaa
     2941 actatcaacc tgattatatc gctcacaaac ccttagaagt tttggcgtat tttcaatagc
     3001 atagactggg taacaattcc atttcagaag aaaatgaagt aatactcaat gaaaatcaaa
     3061 gagcaaacta ggaaactagc tgcgggctgc tcaaaacact gttttgaggt tgcagataga
     3121 actgacgaag tcagtaacat atacatacgg caaggcgacg ttgacgtgat ttgaagagat
     3181 tttcgaagag tataagtctc tacataataa aacgcatatt accaaggttg tttaacttga
     3241 taatatgcgt ttttcttttt tattcaatgt gggttgtttg attagcaaag gcgataatag
     3301 cttgcttcaa ctcatctcca ctgagagtgc ggaactctcc aatcttttga ttgatggatt
     3361 ctaaaggcat gacattaacc ttaccaacga aaatcttatc cataacttga ttgtcaacga
     3421 gttcggttga taccaagagt tcttcgtaga gtttttcacc tgggcggatt ccaacttcaa
     3481 cgattggaat ttcactttca gtatggccac ttagaagcac catcttcttg gccaagtcat
     3541 aaatcttgac tggtttgccc atatcaagga taaagacttc cccatctttg gcataagcac
     3601 cagcatggat aaccagacgg ctagcttctg gaatggtcat aaagtaacgg gtcatgcgga
     3661 agtctgtcac cgttacaggc ccaccttcag caatctgacg ttcaaagact ggaatgacac
     3721 taccacggct accaagaaca ttcccaaaac gaactgcaca gtaggttgat tggctacgtt
     3781 ggttaaagcc agtgacaatc aactccgcca cgcgcttggt tgctcccata acatttggtg
     3841 gattaactgc cttatctgtc gaaatcataa ccatcttaga cactttagct tcatcaacag
     3901 ccttagcaac attgtaagtt ccacggatat tgtttttgaa ggcttctttt ggattgcgct
     3961 ccatcatagg aacatgcttg tgggctgccg catgataaac aatagcaggt ttgtactgct
     4021 caaagacttg caacaaacga tcatagtctt gaatgtccgc aatcacaggt acataatcaa
     4081 tcccttggaa cttacgaatc aattcatgat aaacaaggta gattgagttt tccccatgac
     4141 cgagcaagac aatgcgttca ggattgaagc gactaacttg acgacagatt tcagaaccga
     4201 ttgaacctcc agctcctgtg actaagatgg tcttacctgt cagttctgca cccagacgcg
     4261 attcgtcaag acggatttcc tgacgaccca aaaggtccgt aatatcaatt ttttggaagc
     4321 cagtacctgc ttggtgaagg ccctgaacaa cagtttcaac cttaggcatc ttgtaacatt
     4381 tgacacccag cttattacac atctgcaaga tacgctcata ttctgacgga tccagcgacg
     4441 gaatcgcaac gatgacacgc tcgatttgat ggcgtttggc taattcaggc agattgtcat
     4501 aagagcccaa aacaggaata ccaccaagtt tttgaccctt tttcttagaa tccttatcca
     4561 aaataccgac cagttctaat tcactggttg gatgttggta actatccata aagagagccc
     4621 caccatcacc ggcaccaatc aagaaggtcc gacggtgttc tccatcacca ctaccttttt
     4681 tgcgtctgga gtagattaac tgccaagtaa tccgtggcaa taaaatcaag aaggtactca
     4741 acaagataaa gagaatgata aaacggatgg agaagagtgg caaaaaggca taacagatac
     4801 tatatgacaa gacactgcta gcagtcacac caaaaaagat tttcatgaaa tccgtaatct
     4861 tgctgtaacg actaatgctc gcgttcaacc cccaaaaacc aatcatcaat tgatagaaca
     4921 agaaggccaa actcgtatag ataatgtagt caacaggtgc tggattaatc agcccataaa
     4981 ataaaatata agatacaatg atggaaacca ccatactgaa aatatcaaat attccccaga
     5041 aaacctgctt ttgttgttta tttaaaattt ccaccagatc aatcacataa tctgttagtt
     5101 ttttattcat agaaatctac tcctccttaa aagagtttta ctatattgtt attatagcat
     5161 attttgattt atttggctta ttttatccaa ataaattatt gttctcttgt actccttctt
     5221 ccatttaaat cctctaatta aacctacaat cgtcccaagg ccataagcaa agtgaatgga
     5281 aaataaaaga aagggcatca caattagaaa tccattttta tgttttaata aagtcagcaa
     5341 agtgagtagt gacaaaagta gaaaataggc acctaatagt aaagttatga atacgaatgt
     5401 gatcggtaac aatgctagac taaacacaag actcaaaaca aataaacaag gaacatagtg
     5461 aaataatgat aaacacttaa actgaacatg acttgtcaag ccaatccaca aaccatttga
     5521 atacttttga tgcagcattt tcttgaatgt tggtcgaata tactgataag atagaatact
     5581 tgggctatag cggattttat aaccatgttc tcgaattcta taatgaatat cattatcttc
     5641 agttcggcca agttgctcat ttactaaacc aaccttctgg aaaacctctc gtttatacat
     5701 cccatgaaaa atagaagaaa catatctatc ctcggaacta tttcgataat tggcaatact
     5761 actgccaaac atattttcct caacaagatg caaggtctct gcccattttc cttttccttc
     5821 gacaatcgtc ggtctaggcc ccccacagac aaattcacct tgttgaataa tagccacatt
     5881 gttcattaca aaactctcag taacttttga atgagcatca atttttaaaa taaggtcccc
     5941 tacagaatgt ttaactccca ggttaaaacc actagcttga tttttcttag gattgttata
     6001 caatctaatt gagttaaact ctgtatcttc ctttataaat tgctgaatga tagctgtggt
     6061 cccatctgtg gacatagcat ttataaatag aatttcaata ttctctttag gataagtttg
     6121 attttttaag tcttcaatta gaccaggcag atatttttct tcattgtatg cactgattac
     6181 aatggatacg agaagacttt taacattttg agtcactact actctcctga atttttcctt
     6241 ccaccattct atcataattt tcaagacttt cccattttta tcttgaaagc cagaaacctt
     6301 acttgacatt atagtgaaaa agccttaaaa taagctgtta ttaaaatcag ctagaagagg
     6361 tattatatga aaaagcaatc actctttttt gttccaggta ttatcctgat tggtgtttcc
     6421 ttgcgaactc cttttactgt tttacccatt attttgggaa atatttcgca aggtctggag
     6481 gtagaagtta gttcgcttgg tgtcttgacc agcctacctc tccttatgtt taccctcttt
     6541 tcaccatttt ctacccgact ggctcagaaa atcggcttgg agcatctctt cacctacagc
     6601 ctcttcttct tgaccatcgg ctcactcatt cgactaatca atctgcccct gctctatcta
     6661 ggaaccttga tggttggggc aagtgtcgca gtcatcaatg tcctgcttcc tagtcttatc
     6721 caagccaatc aaccaaagaa aattggtttt ctgaccacct tatatgtaac gtctatgggg
     6781 attgcaacgg ctctggcttc ctatctagct gtgcccatta cacaagccag ttcttggaaa
     6841 ggacttatcc tcctcctcac gttactctgt ctagcaactt ttttgatctg gctcccaaat
     6901 caccgctata atcatagact agctccacaa accaaacaaa aaagtcaaat aaaggtcatg
     6961 cgtaataaac aggtttgggc aattattatc ttttcaggtt ttcaatcctt gatcttttac
     7021 accgtcatga cctggttacc taccatgtct atccatgcag gtctatccag tcacgaagct
     7081 ggcttgctga cttctatctt atctctgatt agcattcctt tttcaatgac catcccaagc
     7141 ctgacaacca gtttatctac tcgcaaccgt cagctcatgc tcactctggt ttcactagct
     7201 ggtgtggtcg gcatttccat gctctttttc ccaatcaata atttcattta ctggcttgcc
     7261 atccatctcc tcatcggaac cgcaaccagc gccctcttcc cttatctcat ggtcaacttt
     7321 tcactcaaga caagcgcccc tgaaaagaca gcccaattgt ccggcctatc tcaaacagga
     7381 ggctatatcc tagcagcctt tgggccaacc ctctttggtt acagttttga cctgttccac
     7441 tcttgggtac catctgtagc tgccctcttg ctcatcgata tcctgatgac tgtggccctc
     7501 tttacagtgg acagagcgga taagatcctt taaacttcta gttttagcta gaagtttttt
     7561 atatataaaa attttacaca tttctcttga cagggctttc ttttagatgt acaatgtatg
     7621 tgtagaaaaa ttatatataa aaatcttaca cattagaaaa ggaggtttcc catgtacttt
     7681 ccaacatcct ctgccttgat tgaatttctc atcttggccg tactggagca gggtgattct
     7741 tatggttatg agattagcca aaccattaag ctaatcgcta atatcaaaga atccacactc
     7801 tatcccattc tcaaaaaatt ggaaggcaat agctttctga caacctattc tagagagttc
     7861 caaggtcgca tgcgcaaata ctactccttg acaaacggtg gtatagagca gctcttgacc
     7921 ctaaaagatg aatgggcact ctatacagac accatcaatg gcatcataga agggagtatc
     7981 cgccatgaca agaactgaat acctgactca gctagaactc tatctcaaga aactacctga
     8041 agctgaccgt atcgaagcca tggactattt cagagagctc tttgacgatg ctggagtcga
     8101 aggagaagaa gaactcatcg ctagtttggg aactcccaaa gaagcggccc acgaagttct
     8161 atccaatctt ctcgataaaa aaatcaatga agcacccgct caaaaaaata accgacaaat
     8221 tttacatatc gccttgttag ccctccttgc agcacctatc ggcattcctc tgggaatcgc
     8281 catcctcgtg accctgttcg caatccttgt agccgctttg actgtcattc tggctttctt
     8341 tgcagtttcc atactgggta tcatcggcgg attcctattt ttagttgaaa gtttcactat
     8401 cctcgcccaa gccaaatcag cctttatctt gatttttggt tctggtttac tggctatcgg
     8461 tgcttcttcg ctagttttac ttggcatttc ctatgtagct cgcttcttcg gtctactcat
     8521 tgttcgtctg gtacaatttg ttcttaaaaa aggaaagaga ggtaatcagc atgcgtaaat
     8581 ggacaaaagg atttctcatc tttggtgtgg tgactaccgt tatcggcttt atcctgcttt
     8641 ttgtaggtat ccaatctgac gggattaaga gcctactttc catgtccaaa gaacctgtct
     8701 atgatagccg tacggaaaag ctaacctttg gcaaggaagt cgaaaaccta gaaattactc
     8761 tccaccaaca cacgctcacc atcacagact ctttcgatga tcaaatccac atttcttacc
     8821 atccatctct ttctgctcac catgatttta tcaccaatca gaacgataga actctgagtc
     8881 tcactgataa gaaactgtct gaaactccgt ttctctcttc tggaattggt gggattcttc
     8941 atatcgcaag tagctactct agtcgttttg aagaagttat tctccgacta ccaaaaggga
     9001 gaactctaaa agggatcaac atctcagcca atcgcggaca aaccaccatc ataaatgcta
     9061 gccttgaaaa tgcgaccctc aatacaaaca gctatatcct ccgaattgaa ggaagtcgta
     9121 tcaaaaacag taaactcaca acgcccaata tcgttaatat ctttgataca gttcttacag
     9181 atagtcagct agagtcaaca gagaatcact tccacgctga aaatatccaa gtccatggca
     9241 aggttgaact gactgccaaa gattatctca gaatcatcct agaccagaaa gaaagccaac
     9301 gaattaactg ggacatctca agcaactatg gttctatctt ccaattcaca agagaaaagc
     9361 ctgaatcaag aggtacggaa ttaagcaacc cttacaaaac tgaaaaaacc gatgtcaagg
     9421 atcaactcat tgcgagatct gatgataata ttgatctaat atccacacca agcagacgtt
     9481 gacaaaaacg cttacatctg ctactatgga agcatattta tctaactaaa aaggaggttc
     9541 taccatgaaa caagaatggt ttgaaagtaa tgattttgta aaaacaacaa gcaagaacaa
     9601 gcctgaagag caagctcaag aggttgcaga caaggctgaa gaaacgatag ccgatctcga
     9661 tacaccaatt gaaaaaaata ctcagttaga ggaggaagtc tctcaagctg aagtcgaatt
     9721 ggaaagccag caagaagaga aaattgaaac tcctgaagac agtgaagcga gaacaaaaat
     9781 agaagaaaag aaggcatcta attctactga agaagagcca gacctttcta aagaaacaga
     9841 aaaagtcact atagctgaag agagccaaga agctcttcct cagcaaaaag caaccacgaa
     9901 agagccactt cttatcagta aatctttaga aagtccttat atccccgacc aagctccaaa
     9961 atctagggat aaatggaaag agcaagtgct tgatttttgg tcttggctag tggaagcgat
    10021 caaatctcct acaagtaagt tggaaacaag tatcacacac agttacacag cctttctctt
    10081 gctcattctg ttttctgcat cttccttttt ctttagtatc tatcacatca aacatgctta
    10141 ctatggacat atagcaagca ttaacagtcg cttccctgag cagctagctc ctttaactct
    10201 tttttctatc gtctctatcc tagtagcgac aacactcttc ttcttttcat tcctcttggg
    10261 tagtttcgtt gtgagacgat ttatccacca ggaaaaggac tggacgctag acaaggttct
    10321 ccaacaatat agtcaactct tggcaattcc aatcttcctc actgctattg ctagtttctt
    10381 tgctttcttt gatagcctac gatttacagc cctcttgtgt gtgattagca ttggaatcat
    10441 tctgcttgcc agtctccata tcattacaag accaagtcaa gcaagtgaaa ccgactcctt
    10501 ctatcaatta ttcttgtctg tccttgtgaa cggagttatt atcctcctct tctttgtagc
    10561 tgaagtggca ctgattggag attatcttcg tatcttggcc tttctttaaa attcaatcct
    10621 gtcatccttg gcaggatttt ttctatgtca aaaaagcaag tcgattgacc tgcttctgct
    10681 ttacttttct tgtgctaatg ttttaaaatc tttgtctaat atgggttgca tttctatttg
    10741 attggcgtct agctggtggt aaaaagatgg gggtaatacc tctaagaatt ttgcatagtc
    10801 caagcgggca atggcttcat agtcttctgg tttagagccg tctcctgtga tttgaaccaa
    10861 gtcaatctcc cactggactt ccttatccac caattgctca atataggctg caggaacaaa
    10921 cggttctctc ggtaaaactg tcttgactcc ttgagctaga tggtaaacgc catgcacttt
    10981 tccttctcca tcctgataga aggaaactct cgcaaagtag gcatctgtct cttgaaccgc
    11041 acgcacacgc gcttcaaact gagccaagcc atctgcctct aaaaagcttt tcaagttctc
    11101 acgactaaag aaaataggat taaaaattcc ttggcaaatc gtaaaacgag ctacagggtc
    11161 tgctagatag gcttgaatac ttgcttggaa ataagcttca aaatcaaaac catctagccc
    11221 ttcaatatca gtccctgtat aagcaagcaa agcatctaaa aatgacttga taatctgcca
    11281 gtctgtcttt gttagtaggt caggaagatc gacacggtaa gccttttgac catcagcata
    11341 actgacctta aaaagaaatt gtgattgccc cactatcgca cactcaatat actcgagacg
    11401 attaagaggc tgacggagat agactacatc atagctatgt gactccaaac cgtctagcaa
    11461 ggccaagatc gacttggcat tcaaaatctc ttgttctcct aaaatgctct gtttatttgg
    11521 aataaaaaat gttttcgcca taactggact cctttgaaat cgtttacata cagtatacct
    11581 tatttttctg aaagatacaa aaacaaactt tatattcttc gaaaatctct tcaaaccgcg
    11641 tcagcttcgc cttgccgtag atatatgtaa ctgacttcgt cagtcttatc tacaacctca
    11701 aagcagtgct ttgagcagcc tgcagctagc ttcctagttt gctctttgat tttcattgag
    11761 tattagattt ttgagtacaa agcatagaaa aacagcccct gaggactgtt tgatcttata
    11821 cagtagctgc ctgatccaag ctttcaccga tagcggctag gcgctcaatc acttcagctt
    11881 gtgtcaattc attttttgaa acatagcggt tacgtgggtg aacacggcac tcgtgtgagc
    11941 atccacgaag gtacttgtct tcattttctt ctgatgtcaa gatacgacgg ttacagaagg
    12001 gatttccaca gttgacataa cgttcacatg gtgttccatc aaaccagtct ttccctacga
    12061 tggttgggtt gacatggttg acatcaacgg caatacgctc gtcaaagacg tacattttcc
    12121 catcccaaag ctcaccttga acttctgggt ctttaccgta agttgcgatt cctccgtgca
    12181 attggccaac atctttgtaa ccttcacgaa ccatccagcc tgagaatttc tcacagcgaa
    12241 caccacctgt acagtaaacc acgacacgct tgtccatgaa tttttctttg ttgtcacgga
    12301 cccattgtgg taactcacgg aagttgcgaa tatctgggcg aatagcccca cggaaatgtc
    12361 ctaggtcgta ctcataatcg ttacgtgtgt caaggacaac ggtatcttta tcaagaagcg
    12421 cttctttgaa ctcttttgga gacaagtaag cacctgttgt ttcaagtggg ttgatgtcat
    12481 tgtcaaagtc gttgtcttcc aaaccaaggt ggacaatttc tttcttgtag cgaacaaaca
    12541 tcttcttgaa ggcttgttca ctttcttcgt caatcttgaa ccagagatct tccattcctg
    12601 gaaggctgtg aacgtagtcc atgtattttt gagttgtttc atagtcacct gaaactgttc
    12661 cgttaattcc ctcgtcagcg actaggatac ggcctttaag gccgattgat ttacagaaag
    12721 ccaagtggtc tgcagcaaat tgctctgcat tttcaattgg agtataaagg tagtaaagta
    12781 agacacgaat atcttttgcc ataagatttg ttctcttttc tattcttaaa ttttctaaat
    12841 tttttattta tccatactag tatacctgct tgagaaaacg aatgcaattt atttgactgg
    12901 aaattgtaga ggattctcga aatttcctga atggttaaaa taaggacaag agaaaacagg
    12961 gatatctata tccttgtgcc caaaaaacca ctgccctccc cagaccaacc tgaggaaagc
    13021 agtgattctt attttaggag ttaggaatga atacacgaaa tcaatttagc tgattatttt
    13081 ttgtttttca agaattcatc gtattgtttt tgcatttcgt tcaatacttt ttcgtaggca
    13141 ccttcagatt tcaatttttc catcaattct ggaatcgctt tatctgggtc tacagtacca
    13201 gtgttgatag ctgtatcaaa ttgttgcatt gtgttagcaa tagctgagat ttcagatttc
    13261 acattgtcag tattgaagat aaatccaagc gctggagatt ctttagcttc tgccaattct
    13321 ttcttagaat tttcgatttg ttggtctgta acgttttcgt tgatgtaaag gatccagttg
    13381 ttaccagtgt tccatccacc catgtgagtg tttcctttgt agccatcaag aacgcgaaca
    13441 cggttttctt taccttcaat tttttcccag ttcttgcctt ctggaccgta aacaagaccg
    13501 ttcaagagtt ctgggttcgt attcaagagg ttcaagattt ccattgattt ttctttgttc
    13561 ttagagttgt ttgagatgac aaagttagca acttgtgttg tttggttttt cttgatgaag
    13621 ttagtaattg gtttgatttg gatatctttg ttggcaacac gtgaaagcaa gctgttaccg
    13681 tagtcagctg gtcctactgt ttcttcacga acgaaccaag tatcttgttg aaggtcaaag
    13741 gaagtatcgc ttgttgcgac gtcttttgga atgtagccag cttcatagaa tttgtgaaga
    13801 gtcttcaagt gttctttgaa acgaggtact tcgtaacggt ttacaacttt agtagtatcg
    13861 ccttcaaggt caataacgaa tggaagaccg tttgctactg ggtagtcaaa gttatcagat
    13921 gggatgaaaa ctttaccaat agcaaatggt actacgtctg gagctttttc tttgatttgt
    13981 ttcaagactg gctcaagagt ttcgtaagaa gtaacacctg aaatatcgat accatatttg
    14041 gcaaggagag ttccgttgaa ggcaaagttt tgagatgatg ctacgttggc tgcaactggt
    14101 acagcgtaaa tcttaccatt tacagtatta cccttgatat aagctggatc aagtgccttg
    14161 taaaggtctt taccttcttt tttgtacaat tctgtcaagt cagcataagc acctttttga
    14221 gcatttacaa tatagttatc tgcaaaggcg atatcatagt tttcaccaga tgatgtgata
    14281 actgacattt tcttaccata gtcaccccag ccaaggtatt ggatatccaa tttagcacca
    14341 actttttctt cgatgatttt gttggcattt gctaacaatt catccaagtt atctggtttg
    14401 tcaccgattt ggtacatttt gataacaggt ttgtcacctg aatcagcagc ttttttgctg
    14461 ttacctgtca agttgccaca agcagcaaga cctgcagcca aagcaactac actagcagat
    14521 gcaaaagcat attttttcca gtttttcatg ataaaaactc ctttttttat ttttaaactt
    14581 ataaacaatg taatgatctt aacttcacgc aagggaagtt tggaaacaag tgctattctt
    14641 tcacaccacc gatagtcaaa ccttttacaa agtagcgttg gaagaatgga tacaaaatcg
    14701 cgattggaag ggttgctacc acaaccatgg ccatacgacc tgtttctttc ggtagagcaa
    14761 ctcccagttg accagtcaag ccgaccgctt tggcaatgta gtccatattt tgttggattt
    14821 gcatgagcaa atattgcaat ggatacaagt tatcactctt gatgtaaaga agggcgttga
    14881 accagtcatt ccagaaacca agagctgtca aaagcgtgat ggttgcgata cctggtagtg
    14941 acaatggcaa acagatttgg aagaaaatcc gggcctcact ggcaccatcg atacgagccg
    15001 attcgagaat ggcttctgga atggtcttct tgaagaagga acgcatcaag atgatattga
    15061 atggtgagag aagcattgga acaatcaagg cccaaacagt gtcaccaagc tgaagtacac
    15121 gggtcaccat gatataacct ggtaccaaac cagcgttgaa caacatactg agaaggacga
    15181 agatggtaaa aaatctgcga tacttaaagg ttgtccgtga aatagcgtag gcataggttg
    15241 ttgtgataaa gacatttgtc aatgtcccaa ctacggttac aaagacagag atgaagaggg
    15301 cttgtaggat tttatcctta aactgtgcca aaaactcaaa accgtctaag ccaaattggg
    15361 atgggaagaa gctatagccg tattggagga ggcttttctc gtctgtcact gaaataatga
    15421 taacgaatac aaaaggtagg atacaagaga gggcaatcaa acccgaaatg atactgaaga
    15481 agatatctgc tttcttactg aaggagtgaa tgccgacatt atcaattttt tcttttttaa
    15541 ttttcttttt tgccatattc tcctcctttc tagaacaaag ctgagtttgg atcgactcgt
    15601 cttgcaagca agtttgatag gataaccaga atcaaaccaa caacggattg gtaaagaccg
    15661 gctgctgcag ccataccgat atctgctgtc tgagtcaaac cattaaagac atatacgtcc
    15721 aaaacgttgg ttacattgta aagctgacca gcattgtgtg ggatttgata gaagagaccg
    15781 aagtctgcgc ggaagatatt tccgactgca aggatggtca atacagttac aagcggagtc
    15841 aactgaggaa tggttacgtt gcgaatacgt tgccacttgc tagctccgtc cactgtcgct
    15901 gcttcgtagt aggttggatc aattcccatg atcgtcgcat agtacatgac actgctatat
    15961 ccaaagcctt tccaaatacc taggaaaagt aggagatagg gccagatgcc caggtcagcg
    16021 tagaaattga cttctttgag accaagactt tccaatagat gattgaacac ccctttatca
    16081 atatttagga aggcatctgt aaagaaacta atgataaccc aagacaagaa gtaagggaac
    16141 aacatagaag tttgaaaaat cttcaccatt ctcttagaac ggagctcgct gaggataatg
    16201 gcaatcccta cagatacaac taaacctaga aagataaagc caagattgta gaggacagta
    16261 tttcgtgtga taataaaggc gtctcttgaa ctaaataaga atctgaaatt atcgagtccg
    16321 acccatttac tatttatgat actatctatg aaaccattac tggtcatgtg gtagtctttg
    16381 aaggcaacca cgttcccaaa tactggaatg taaaagaata gaatcaacca gagtgcccct
    16441 ggcaaaacca tcaagagaaa gatccagttg tctctcaatg tttttgaaaa ctttttcata
    16501 atttcctccc tttttatttt gatatccatc taaaaattct tttttagact tttgataacg
    16561 attacattat tagtatactc ctatttgcag gttaggttaa actcctaatt atagaaaaaa
    16621 ctccacaaat tatgtagcag atttaaaact ttatcaccac tatcaaacaa atgtcctaaa
    16681 tcaattgttt attttatctc tattagccca gtgatggcgt cactctgtta taagcatcca
    16741 acaacggggt atactgaaaa atctccagac tagggaactc agcgatagtt cctaatctgg
    16801 agatttttaa tatgttatta ggcgtttgct ttcaacttag caataacctc tttaagatta
    16861 tcaatcaact ctgcttcagt atgctcagag cctttttcat ctgccaagaa caaaactgct
    16921 ttttgaagtt cttcttgaga gttttcaagg acatccttat ctgctgtttc tttgcccgct
    16981 gtttgtcctc catccttagt tgctgactgg ctttccttaa tggactctag ggaagcaatg
    17041 gcatctttga ctgtttgcaa gatatcacgt aaaccttgct ctgtcaaact atcatctgca
    17101 aaagctttct tagcctctgc caaaaccaga cgtgctgaat ctgtggtagg attcgataca
    17161 cctgtcaatg atctcaaaag attttctaag gtttgagtct gcttactaat actagactaa
    17221 aatcaaaaag cattatataa cagtgatatg aaatcaacta aagaagaaat ccaaaccatc
    17281 aaaacacttt taaaagactc tcgtacagct aaatatcata aacgccttca aatcgttcta
    17341 tagtaaaatg aaacaagaac aggacaaatc gatcaggaca gtcaaatcga tttctaacaa
    17401 tgttttagaa gcagatgtgt actattctag tttcaatcca ttatatttcg tctgatgggc
    17461 aaatcttata aagagattat agagctttta tagtagtttg aaataagatg tgaacaactc
    17521 tatcaggaaa gtcaaattaa tttatagaaa tattttagca gccaaggtgt actgttataa
    17581 attcaataca ctatacttgg tggtttagct ctcctgtttt ctcttttagc tttaaccagc
    17641 cataaatggt attacgtgag atttgaaaaa cgtgtgatgc ttctgttata ctacctgttc
    17701 gctcacaata agagagaact tttttacgaa aatctattga atatgccata aaagattata
    17761 ccacattgtg tactattttt ggttcatttt actatatcac tttggactat atcggtctag
    17821 ttatgtctaa acgattatag ctggatacta agagaaatca aaaaagcact aagggagaac
    17881 gtcccaaagt gcttaatatc aaggcctcaa agcctatctt atttaataaa atattacaac
    17941 attttgttgt agaattcaac gacaagtgct tcgttgattt ctgggttgat ttcgtcgcgt
    18001 tctggcaagc gagtcaatga accttccaac ttttcagcgt cgaatgatac gaatgctgga
    18061 cgtccaagag tagcttctac tgcttcaagg attgctggaa ctttcaatga tttttcacga
    18121 actgagatca cttgacctgg agttacgcgg tatgatggga tatcaacgcg tttcccgtca
    18181 acaaggatgt gaccgtggtt tacgaattga cgagcttgac gacgagtagt cgcgagacca
    18241 agacggtaaa caacgttatc caaacgacgt tccaaaagaa gcataaagtt gaaacctagg
    18301 attccgcctt tgatttttgt agcttgtacg aacaagttac ggaattgttt ttcacctaca
    18361 ccgtaagtga aacgaagttt ttgtttttca gccaattgca aaccgtattc tgacaattta
    18421 gaacggttgt ttggtccgtg ttgtcctggt acgtagttac gacgtgccaa ttctttacct
    18481 gtacctgtaa gtgaaaggcc aaggcgacga gcttgtttcc aagatggtcc tgtataacgt
    18541 gacatatgaa tgtcctcctg atataaataa tatttcggtg gaaatagtca cttagaaagc
    18601 cctgattcgt gcagatgccc ttcgcctaaa cagccaaggt tacttgtcat aagacacctg
    18661 ttgacgagct tcatgctttc ctgctgatat ttcacacaaa atctattcta ccatgaatag
    18721 ctggatttgt aaaggggttt taggctttat tttcactacc agagaggttg agaacgaggg
    18781 taaaggtact tcctagaccg tactggctgc tgactgtgat ttccccaccc aattgatggg
    18841 ccaattcacg cgcaatcgca agtcctaatc catgaccacc tgtcttcatg ttacgcgaag
    18901 tttcgacacg ataaagacgt ttgaaaatat tttccaaatc ctctggggca ataccctgcc
    18961 cttcatcggt cacactgatt gaaagctggt ccttctccag cttagccacc acttccagct
    19021 tggttcctgg agcagaatat ttaaaagcgt tatcgaccag attcaccaag atacgagaaa
    19081 gcttagcata atctccctca atccgggcag actctgggat tacctgcaag tggacatctc
    19141 ttctctcctg ctcaatcaaa aactgaaatt cactcatgca ctcaattaag agcttgtcca
    19201 gaaaaatact gtctttactg gtagtttcca cctgatttct agctgtgttt agggtcaaaa
    19261 aattcaactc ctcaaccagt ttattgagcc tctccgtctg gcgtccaatg gttgctagat
    19321 aatgagcttg ctccgactcc ttgataatcc catccaaaat cccttctacc gtcgcttgaa
    19381 tcgaagtgat aggggtctta atatcatgcg acaactgggc aatcatcaag cccttttctc
    19441 gttcgctttc ttccaaggaa tcaaagctta cctgcaaatc atgggacatc tcattaaaag
    19501 tttgccctaa ttgctgaaat tctacaggac cttgaacctc caaatttgaa ggaaaatcct
    19561 tggccgctac ccgcttggca tgctccttga gtttgcccaa cgacgtaaag actggcaata
    19621 ggagaaagag actaatccca gcaccgacaa ggctggcaac gatggtcatc ccaagcaaaa
    19681 agtaaatctc gcctttcgca atcagcattt tttgaacagc ccaaaaaaca accaaaatgg
    19741 ttaagagggt tgaaataata tatccaacca aaatataact ttttagtttc atgtttgtcc
    19801 tctcggtttc tctatcttat atcccaaccc ccaaactgtc ttaatagtgg gcgtttggtc
    19861 actactatat tttgccagct cctgtcgaag agcatggata tgcacattca aggtattggt
    19921 gtcatccacg tagtcttctt tccagatctt ttcatagagg tctgtcttgg agaaaactcg
    19981 ctctggattg ctagctaaaa tccacagcaa ttcaaatgat ttaacagtta aatccagcat
    20041 ttcttctcct atttgaactt catgactact atgattcatt tttagattgc caagggaaat
    20101 cagctctgtt tcgcccccac gatgaaggcg gcgcaaaata ttgtggacac gcaaaactag
    20161 ctcacgtggg ctaaaaggct tagcaataaa atcatctgct cccaagctca ggccgtaaat
    20221 cttgtcctgt tcactggtct tagcagtaat aaataggaaa ggctgctctg gtgataagta
    20281 ttgaacctca ctgattaaat cataaccatc catccgaggc atcatgacat ctgtgataat
    20341 caaatcaatc ggttttttct tgaacagctc tagcgcttcc agtccatcat gggctaccaa
    20401 gacctgataa cctgcctgaa ttaagtatct ctgatgaata tctgtgattt ctacctcgtc
    20461 gtcaacgagt aaaattgtct ttcccatctg tctctccttt gataaaaaca gtgctatact
    20521 gctttaagta taacactatt tttattgttt tacgatgatt ttaatctgct attgaaagaa
    20581 agtcctgatt gctgattgag ttgttaaact aatcttagtc agcccactat ccatcattta
    20641 tttccttagc tgattagttt tcttcttttt tgtttttcaa acctagacca ccgagtaaac
    20701 ctgcaagcgc aagcccaagg aaaccaatac ttgccattga tgtttgagtc tcaccagtat
    20761 ttggtagcat agctttatcc tctgacatca tcgtatcaga catcttgtta gcagaagcag
    20821 ccatgttttc acctgccatc gtgttggtag aacttgtcat ggtgtcagca ggcatgctat
    20881 ctgtagtacc tgtagcatga ttgtgattca tcggagtcac gccagaacca gagttagaag
    20941 gtgataatga accatttgct gtgtctgatg tttctttaac atttat
//
LOCUS       DAVHBD010000042        20895 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000042 DAVHBD010000000
VERSION     DAVHBD010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.042"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            142..279
                     /locus_tag="VVK04_001661"
     CDS             142..279
                     /locus_tag="VVK04_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEU3990293.1"
                     /translation="MPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKI
                     F"
     gene            complement(417..1721)
                     /gene="eno"
                     /locus_tag="VVK04_001662"
     CDS             complement(417..1721)
                     /gene="eno"
                     /locus_tag="VVK04_001662"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU3990294.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            1885..2331
                     /locus_tag="VVK04_001663"
     CDS             1885..2331
                     /locus_tag="VVK04_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU3990295.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2328..3443)
                     /locus_tag="VVK04_001664"
     CDS             complement(2328..3443)
                     /locus_tag="VVK04_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU3990296.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3452..3781)
                     /locus_tag="VVK04_001665"
     CDS             complement(3452..3781)
                     /locus_tag="VVK04_001665"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU3990297.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(3726..4097)
                     /locus_tag="VVK04_001666"
     CDS             complement(3726..4097)
                     /locus_tag="VVK04_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU3990298.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4156..5589)
                     /gene="glgA"
                     /locus_tag="VVK04_001667"
     CDS             complement(4156..5589)
                     /gene="glgA"
                     /locus_tag="VVK04_001667"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU3990299.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5586..6725)
                     /gene="glgD"
                     /locus_tag="VVK04_001668"
     CDS             complement(5586..6725)
                     /gene="glgD"
                     /locus_tag="VVK04_001668"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU3990300.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6715..7857)
                     /locus_tag="VVK04_001669"
     CDS             complement(6715..7857)
                     /locus_tag="VVK04_001669"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU3990301.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(7847..9775)
                     /gene="glgB"
                     /locus_tag="VVK04_001670"
     CDS             complement(7847..9775)
                     /gene="glgB"
                     /locus_tag="VVK04_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU3990302.1"
                     /translation="MDNREALKTFMTGENFHLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            complement(10255..11679)
                     /locus_tag="VVK04_001671"
     CDS             complement(10255..11679)
                     /locus_tag="VVK04_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU3990303.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVCREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     SLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(12223..14502)
                     /gene="pulA"
                     /locus_tag="VVK04_001672"
     CDS             complement(12223..14502)
                     /gene="pulA"
                     /locus_tag="VVK04_001672"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU3990304.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGVIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(14614..16572)
                     /gene="ligA"
                     /locus_tag="VVK04_001673"
     CDS             complement(14614..16572)
                     /gene="ligA"
                     /locus_tag="VVK04_001673"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU3990305.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDTMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLNYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(16665..17843)
                     /locus_tag="VVK04_001674"
     CDS             complement(16665..17843)
                     /locus_tag="VVK04_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU3990306.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(17923..18786)
                     /locus_tag="VVK04_001675"
     CDS             complement(17923..18786)
                     /locus_tag="VVK04_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU3990307.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(18789..20690)
                     /locus_tag="VVK04_001676"
     CDS             complement(18789..20690)
                     /locus_tag="VVK04_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU3990308.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQVISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         6320 a         4586 c         3701 g         6288 t
ORIGIN      
        1 aacgcctttg gatttcggaa ctttgaaaac ttcaaaaaaa ggatttttat cgctctgaac
       61 atcaaaaaag aaaggacgaa ttttgtcctt tctcgagctt agctgacttc aacccactac
      121 agttgacaaa gagccaataa aattccttta aaaacaatca cggacagggt gggtcattcc
      181 gactctgaag tcactacttc catctacacc cacgtcacaa agaacatgaa agatgaagca
      241 atcaatgtac tggataaagt tatgaaaaag attttttaaa aagttttgcc ccttttttgt
      301 cctctaaata caaaaatagc ccttcggata aaatccgagg ggctagaaac gttgttaaat
      361 caacggccga acttttgaat ttcatggttc gggataaaat agttcactga actattttat
      421 tttttaaggt tgtagaatga tttcaatcca cgatattctg ctacttcacc aagttggtct
      481 tcgatacgaa gcaattggtt gtatttagcg atgcggtctg tacgtgaaag tgaaccagtc
      541 ttgatttgtc ctgcgttagt tgcaactgca atatcagcga ttgttgaatc ttcagtttca
      601 cctgaacggt gtgatacaac agcagtgtaa ccagcttctt tagccatttc gatagcttca
      661 aaagtttcag taagagtacc gatttggtta actttgataa ggattgagtt agcagcacct
      721 tcttggatac cacgtgcaag gtagtcagtg tttgttacga agaagtcgtc accaacaagt
      781 tgtactttct taccaagacg ttcagtaaga gctttccaac catcccagtc gttttcatcc
      841 ataccatctt caatagtgat gattgggtat ttgttaacca attcttcaag gtagtcgatt
      901 tgttctgcag atgtacgaac agcagcacct tcaccttcaa atttagtgta gtcgtaaact
      961 ttacgttctt tatcgtagaa ttctgatgaa gcacagtcaa atccaataaa tacgtcttta
     1021 cctggtacat atccagcagc ttcaatcgca gcaaggatag tttcaacacc atcttcagtt
     1081 ccttcgaaac gaggagcgaa tccaccttcg tcacctacgg cagtttccaa accacgtgat
     1141 ttaaggattt tcttaagagc gtggaagatt tcagcaccgt aacgaagggc ttctttaaat
     1201 gttggcgcac caactggcaa gatcatgaac tcttggaaag cgattggagc gtcagagtga
     1261 gaaccaccgt tgatgatgtt catcattgga gttggaagaa ctttagtgtt gaatccacca
     1321 aggtagctgt aaagtgggat ttcaaggtag tcagcagcag cacgagctac agcgatagac
     1381 acaccgagga ttgcattcgc acccaattta cctttgttag gagtaccgtc aagtgcgatc
     1441 atagcacggt caatagcttg ttgatcacgt acatcgtagc caatgatagc ttcagcaatg
     1501 atgttgttta cgttgtcaac agctttttgt gtaccaagac caccgtaacg agatttgtca
     1561 ccgtcgcgaa gttcaactgc ttcgtgttca ccagtagaag ctcctgatgg aaccatacca
     1621 cgtccgaaag cacctgattc agtgtaaact tctacttcaa gtgttgggtt accgcgtgag
     1681 tctaggactt cgcgagcgta aacatcagta ataattgaca ttttttactc tccttatgag
     1741 ttaaattttt tacacctcta taatacctta aaacccctcc tttttcaaga aaaaacgtta
     1801 tctttgtgca acttttcctt aactttataa agtaatcgct ttcttttgtc tgttttattc
     1861 taacttttat gatatactgt tttcatgaca gatttatcaa aacaattact tgaaaaagct
     1921 catggtgggt taaaaataaa tccggatgag caaagacgct atcttggtac ttttgaggaa
     1981 agagttcttg gatatgtaga tattgacaca gcaaatagcc ctcagttaga aaaaggcttt
     2041 ttatttattt tagaaaacct tcaggaaaaa gcagagccac tatttgtgaa gatttcacca
     2101 actatcgaat ttgataagca agttttctac ttaaaagaag caaaagaaac tgatagtcaa
     2161 gccaccatag tatctgaaga gcatattact tctccttttg gcctggttat tcatagcaat
     2221 gcaccagttc aagtagaaga aaaagacctt cgacttgctt ttccaaaact ttgggaagtt
     2281 aaaaaggaag aaccagccaa aacatcctta tggaagaaat ggtttagcta aatcttgcac
     2341 atatttaata agtgcccaat attggcagcc gtgcgctcca gatagagact ggcatttttc
     2401 aaactatctt ctaaaggttc acttttctcc aaaatagaaa agacagcttg gatattttca
     2461 aatggtaggg gaggtaaatc ttcagcaaga ctaccgcaaa tagcaataac aggaactcca
     2521 acaggggttc tttttgcaac acctataggc gctttcccag caaagctttg actatcaagt
     2581 cttccttctc caacaacaac caagtcagca tctgaaactt tcttatcaaa gttgattaag
     2641 tccaagcagg tatcaattcc agacacgata cttgcctgag caaaggcaca caaaccacca
     2701 gcaaggcctc cacctgctcc tgctccttta atttctaatg ttgcaggtga gaatttttca
     2761 taaaaatctt ggatcgcctg atctacgact gcaaacatag tcggatgtag acctttttga
     2821 ttgccaaaag tgtaagtcgc accttgatga ccacataagg gactcacgac atctgctaaa
     2881 atatgaattt gaacaccttc aggaatttta tagcaatttt ctgttgaaac agaagctaag
     2941 tttaataagg attgaccgga agcaggcaag acatttccat ccctatcata aaattgataa
     3001 cctaaaccag cagcaatccc cagtcctcca tcattactgg ccgtgccacc aacaccgata
     3061 taaatatctt taatcccttt agaaatgaga tggagaatca actctccaat accacaagtt
     3121 tggatttgaa gtggatttcg tttctctagc ggaatttttc caagaccaac caagtcagct
     3181 acttcaaata gtgccagttc ccctttttga aaatagcgca tggcttcttt ttgtccaaaa
     3241 gggtctgtca cttggatcca tttttctttt aggtcaagag aatgtcggat agcatctaca
     3301 gtaccttctc ccccatcacc aacagggcag aggagacatt ctacatctgc tatcgattgt
     3361 tggaagcctc tttttattgc ttcagctacc tgttgagctg tcaagctttc cttaaacgaa
     3421 tccggtgcaa ttacaatctt catattttcc ctcattctaa acagtcaatc aaaggaagaa
     3481 cttctaaaaa atccctcttg tcaacatgat gtggtatttc ttttttgagc atttctttgg
     3541 aacaaaaggc gattcctaac tccgccgact tcaacattaa tagattattg accccatcac
     3601 cgattgccac cgttctttct ttagaaagtt ttagtttctt tctccatttt tccagagttt
     3661 cttttttgac ctggggactt ataatttgtc caactaattt tcctgttaaa agaccttctt
     3721 tgacttcaag ctggttggca gtgaaatagg caataccaag ggattttgct aatctctcca
     3781 actattggtg taaatccacc agacaccaga ccaactagga tgccattctt ttggagaata
     3841 gagatgaact ctgggacatt tagcgataga tgaattgagt tgaagacgtt atcaaagacc
     3901 aaaataggaa gaccttccaa caaggacact ctttttctta aactgctttc aaagaccaac
     3961 tctcctcgca ttgctcgact tgtaatctgc gaaatttccg cctcatgacc tgcctctctc
     4021 cctaaaagat caatcacttc ttctaggatt aaggttccat ctacatccaa aacacacaag
     4081 ccttttactt gagacatcag ttctcctctc taaacagcct aaaaatcgta tgaagtcatc
     4141 atacgatttt atctattaat taactaaact atggtacaag tcaaggtatg acttgcaggc
     4201 tgtatcccat gagaagtcac tctccatagc ttgtttttgt aggtttctcc aaatgtctgg
     4261 atggtttcta tacaagtcca atgctgtttg gaaagtccaa tttaaccaat aaggagatag
     4321 attgtcaaag ctaaagccag taccgcttcc ttcgattgga ttgaaagcgc gaactgtatc
     4381 tcgcaagcct ccaacttcat ggaccaatgg caaggttcca taacgcatag ccatcatttg
     4441 agacaagcca cacggttcaa aacgacttgg catgaggaag aggtcacaag cagcgtagat
     4501 ttcctgagca agtttgacat caaaagtgat atttgttgat agcttgtctg ggtaaatctg
     4561 agcaaaccat gagaaagctc cttcaaaggc tggatcgcca gttcccaaaa gaacaatctg
     4621 aacatcttct tgcaagatat ggtgaagact ttcgaccacc acatcaaaac ctttttgacg
     4681 tgtcaaacga gaaacaattc ccaccagtgg aacgtctgct ctaacaggca agccaactct
     4741 ttcttgcaat tttgccttat ttttggcttt cccagacaaa tcttcctgat tgaaatgata
     4801 gtctaaaaga gcatccgtct gaggattata aagatcagca tcaatcccat tcacgatacc
     4861 agatacttta ccagactcca ttttaagaat ctgatccaaa ttacatccaa actgactagt
     4921 cataatttca tgagcatagc taggtgaaac ggttgaaaca cggttcgcat agagaatacc
     4981 tgccttcatc cagttcagac agttgttcca tcgaagggtg ccatcagcgt aacgttcaaa
     5041 gccaactcca aacaaatcac ccaacattcc ttctgaaaat tgtccttgga attctaaatt
     5101 atgaatggtt aaaactgttt caatgtcctc ataggcttga atccaacggt atttttcctt
     5161 caacaagaaa ggaatcatag ctgtatggta gtcatgaaca tggagaagat caggaataaa
     5221 gtcaatcctt tccatagcct caatggcagc cagttggaaa aaggcaaagc gttctccgtc
     5281 atcaaaatca ccgtaaacat gaccacggaa gaaataatat tgattgtcaa taaagtagaa
     5341 ggttacacca tttaatactg ttttcttaat tccacaatac tgtctgcgcc aaccaacgct
     5401 cacctcaaaa tgaagtacat cttcaatctg atttccaaat ttagcctcta ccatatcata
     5461 gtagggtaaa atcactgcaa cttcgtgccc agcttttacc agtgattttg gaagagcgcc
     5521 aatgacgtct cccaaaccac ctgtttttga aaagggtgca ccctctgctg ctacaaataa
     5581 aattttcatg aatgaatatc ctctgttact ttagcacctt tcttaaccac aactggatgt
     5641 tctgcagttc ctcgaatcac aacaccaggc tcaacttcaa cccctttgtc caagatagca
     5701 tattcgacct gagccccttc tccaataaca acacgaggga agagcaggct atctttaacc
     5761 aagctatcct tatggacatg aatattacgt gatagaacag aattagctac ttgaccttca
     5821 ataatactac cagaggcaaa ctgagaagtg cttaccttag atgtattagc atagtaagtt
     5881 ggctcttcgt ttttgacctt tgtataaatc ttttggtttg gtgagaaaag agaatagaat
     5941 ttttgtgatt caagcatatc gatattcgct tgataataag atttaacaga gtgaatattg
     6001 gctagatagc ctgtgtactc gtaggcgaaa gctccctctt ttacagccaa atcccgtaaa
     6061 acatagcgca atttctctgg atgttctttt ttagcttctt cttccaagtg ttcaatcaac
     6121 caaggtgtat caacgacaaa gatatctgta gacatattga acgtttcagc tgttgacttg
     6181 ctatcaaaga gtttatgaga aagaacatgg tctgtttcat ctacatccaa gattgcattt
     6241 acttctgaaa tatctttctt agctagtttt ttataaacta cagtgatagg ctcttttgtt
     6301 gtactatgta ggtggaaaac ttggttcaaa tcaatgttaa taagaacatc gcagttgagg
     6361 gcaaccgttt ggtttgagcc agaacgtttc aaataagtaa gaagctgttg gtagtattct
     6421 tttccaactg tactactttc tacacgggta ttgtaaattc ctagatagta atggctaaga
     6481 agggttgata agccccactc gcgtcctgaa cgaatatggt caaatactga gctgatatta
     6541 tcctgctgga aaataccaaa gacactacga acacctgcat tagcaaggct tgaaagtggg
     6601 aagtcaatca aacgatattt cccaccaaat ggcaaacttg ctactggacg gtggtccgtc
     6661 aatgtcgaca tattgtgaaa accaactgta tttcctaaaa tggcagaata tttatcaatc
     6721 ttcatctgtt gctaccccca ctacttcatt atatcctaca acttgtactt catctgttcc
     6781 atcaatttcg acaccgtcag aaataatcgc accttcacca ataatggcac gtttaatctt
     6841 agctccttga ccaatgatag ctccactcat gataactgaa tcaaggactt ccgctccttc
     6901 gcgaacttgc gcgcctgttg aaaggataga atgtttaaca gttccatcaa cgaaacatcc
     6961 gtctacaact aatgagtctt ccacatgagc atttgccccg aggaagtttg gtggtgaaat
     7021 caagtttctt gagtaaatct tccattgacg gttacgacta tccaaggcat tttctggaga
     7081 aatatactcc atgttcgctt cccaaagtga ctcaatagta ccaacatctt tccaataacc
     7141 actaaattcg taagcataaa cactttcacc tgactcaagg taatttggaa tgacattttt
     7201 accaaagtct gacatgccaa ccttgctctt ttcagcagcg actaacatat tacgaaggcg
     7261 ttgccaatca aaaatgtaga ttcccataga agcttttgta gatttaggtt gagctggttt
     7321 ttcttcaaat tcaacaatac gattgttagc atctgtgttc atgataccaa aacggcttgc
     7381 ttctttaaga gggacgtcta aaactgctac tgtcaagctg gcattattat ccttatgaga
     7441 ctggagcata tcatcatagt ccattttgta gatgtgatcc ccagacaaaa tcaagacata
     7501 ctcaggattg acactgtcga tatagtcgat attttggtaa atagcgtgac tagtcccctc
     7561 aaaccaacga tttccttcac ttgcagaata aggttgaaga atagagacac ctgaattaat
     7621 accgtctagt ccccagcttg aaccattccc aatatggttg ttgagagcaa gtggttgata
     7681 ctgtgtaacg accccaacat tgtgaatccc tgagttggca cagtttgata gggcaaagtc
     7741 aatgatacgg tagcgcccac caaattgcac agctggtttt gcgatgcttt gagtgagttt
     7801 accgagacga gttccttgcc caccagcaag aatcaaagct aacatctcat ttttcatttt
     7861 ctactccttt ttggttttta tttgtgacgg ttttagtaga tttcaagcga cgtttgattt
     7921 tccatacact tgctcccata gccggtaggg taaaggttaa ggtctgctca taatctttcc
     7981 atagtccttc ttgcgtttga acagtttgat tatgttcttt ccaaacgcct ccccactctt
     8041 ccaactcagt attccatact tcttcgtaaa ttcctgcaac gggtagtccg attgtaaaat
     8101 ctttccgctc aacaggtacc atattaaaga tacagactaa catttctccc tttttaccct
     8161 tacgaataaa ggaaagaaca ctctggtctc gattatccgc atcaatgatt tcaataccat
     8221 catagctggt atcaatttcc cacagacagc gatgatcttt gtaaaactgg tttagctgag
     8281 aagcgaaata cttcatctta gcattcattg ggtcttctag gttagaccat tccaactgtt
     8341 cttcagattt ccattctagg aattgaccgt attcgctacc catgaagagc aatttcttac
     8401 cagggtgaca aatttggtac gtatagagat tgcgcaagcc tgcaaattga ttgtaacgat
     8461 ctccccacat cttatgcatc atactcttct tgccatgaac cacttcatcg tgcgagaatg
     8521 gcaagagata attctccttg aaaacataca taaagctgaa agtcaccagg ttaaagtcat
     8581 atttacgata gatcggatct tcttcgtaga aacggaggat atcattcatc cagcccatgt
     8641 tccatttgta gtcaaatcct agaccaccaa tctctttcat tcccgtaatc ttggtcgcag
     8701 acgaactttc ttctgcaatc atcatcacat ctggatattc taacttaata acctcattca
     8761 agcgctgaag gaaataataa ccttcatagt tgagatttcc gccatcttta ttaggtgtcc
     8821 atggagcatc atcatagtcc aaatagagca tgttgctaac agcatccaca cgaataccat
     8881 ccaaatgata gacatcaatc caatgcttaa tgcaagaaat taagaaggac tggacttcat
     8941 tttttccaag gtcaaaatta agggcacccc aaccatggtt atgagcctta ttatggtctt
     9001 ggtattcaaa agtcggtgtc ccatcataat aggctaaggc atcatcgttg atggtaaagt
     9061 gacctggtac ccagtccaca ataaccccaa tattatgggt atgacactcc tcgacaaaat
     9121 cttgaaactc ctctggtcgg ccataagcat gctctaaagc gaagtaaccc ataagctgat
     9181 acccccaact caagcccaaa ggatgggaca tcaagggcat aaactcaata tgagtatagt
     9241 tcatttcaac gagataagga atgagttcat ccttgagctg ggcaaaacta taaggactgc
     9301 catcagaatt tcttttccat gatccagcgt gaacttcata aatattgaca ggacgctctt
     9361 caaagcccca acgttttctt cgtgccagcc aaagtccatc cttccatttc ttctcaggaa
     9421 gctctgttaa gattgcccct gttcctggac gagcctcata cctgacagca aaagggtcaa
     9481 tcttcatcag ttgatgacca ttttgacgtg tgacatgata tttgtaaata tgcccttctt
     9541 gagccatatt ggtaaagact tcccagaccc caaaatcatt tcttaccatt ggaatctgat
     9601 tttcaatcca attggtaaaa tcaccaacca agtgaacagc ctgagcatta ggtgcccaaa
     9661 cacggaaggt atagccatgc tctccattta gttcttccct atgtgctcct agataatgtt
     9721 ggagatgaaa attttcaccc gtcataaagg tttttaatgc ttctctatta tccatatact
     9781 ccccttcttc tgtaagcgtt ttctatgttt ttattatact acctttttag agaagattca
     9841 agtaaattac tatacttctt taattatttt gaaaatctac aacaagttca cttactcgtt
     9901 caattgtaaa tcaatatttt ttcaaaaaat tgcgaaaacg cctttctttt tctactatag
     9961 tgaaatgaaa taaaacatgc gcaaatcgat taaggaattt aatctaattt ctaacaatgt
    10021 cttagaaatc aaagtgtact attttaactc caatgtatta tatatagtaa aatgaaataa
    10081 taacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag
    10141 gtgtactatt cttgtttcaa tctattataa taccaaaaag ttcgtatttt ttctataatt
    10201 attattttat agcaaaaaaa taaaaccagg aaaacaattt cctggtttta cacgttattt
    10261 cacatcaaaa acaatggatt tgacatttgt catcgcttca atgctatatt taattccttg
    10321 cactccagct ccagaacctt tgacaccaag gaatgggaaa ttatctggac cacgctgggt
    10381 tttattatta atgtggactg tacctacttc aagtttttca gcaatttcaa aggctttttt
    10441 gaaatcattt gtaaagactg atgattgaag gccgaattca gattcgttgg caaaggcaat
    10501 agcttcctct acactagcca cacgaatgat tggtaaaaca ggaccaaatg gctcttccca
    10561 tgccactttc atatcttttg taacttggtc aaaaagcact ggccagagaa gattgccctc
    10621 acgtttgatt ggtgtaagag cctgagcttc tttttcttgt gcatcctcaa tcaagctcca
    10681 aatgaagtcg gctgaagcat tgtcaataac aggtgtaata tcagcattgt caaatggatc
    10741 accaactgtt aatttagaaa cttcttcctg aagcaaagta gctaatttat ctgctacact
    10801 ttcgagaaca atgacacgtt taatggccgt gcaacgttgt cctgagtagc taaaggctcc
    10861 cgcaacaatt tgcttggcag catgttccaa atctgcatct tctagtacaa gagctgcatc
    10921 tttcccacca agttccaaca tgataggacg cataccagct aaacgaccaa tacgttctcc
    10981 aataggagtt gaacctgtaa agttgatgaa gttgacttct ttgtgctcaa tgatataatc
    11041 cccaatttct gaaccacgac ctgtaatggt gttgaaaaca cctgccggaa tccctgcttc
    11101 ttcaaatgct ttagccaaca agagtccaga aatggaacct tgtgttggtg gcttaaacat
    11161 gaccacattc cctgcaatca aggcaggtgc aattttagaa gcagataaat taactggata
    11221 attaaaggga gcaatcgcta gcacgatacc aactggttca cgacagacaa cagccagttt
    11281 gtttttactt gctgcctcaa aaccaccacc ttccattgct tgtccagtga tacggagacc
    11341 ttcctcagca gcataacgaa tcaagtctgc tgtacgcact acttctccaa ttgctgcttt
    11401 aatccctttt gctacttctt tggcaaggat agtaccaatt tcttccttat cgcgttctaa
    11461 aatagctgct gttttatgta aataagccgc acgttcaact gctgataaag ctcgccatgc
    11521 tggcagggct gcacgcgcag cttgcatagc ctcatcagct tcagtctgag tcatggctgg
    11581 aactgtaccc aattcttctt gattgattgg tgaataaatc gtaatttctt gttcagatga
    11641 tttccatttt ccatttacta aattctgata tcttgtcaaa ttcttgtcct cctgaaaatg
    11701 attaagatat attttaccaa attttcagaa aataacaacc ctttttgcaa aatttttgag
    11761 attgttttca caagcttgat ttttcaaagt atactcaata aaaataaaaa aatccactac
    11821 gtcaaggcga ggctaatgtg gtttgaagaa attttcgaag agcgtgaatg agtatcatct
    11881 atagtaaaat aaaaaaactg aacaatttgg ttggggacag ccaaaccaat ttctcacaat
    11941 gttttagaaa caagggtgtg ctattccaat ttcagcctac tataactgtc atagattgct
    12001 gaaacaaagt ctaggtaaaa gtcttcataa taaaaagacc tcctatcaaa tgttcaaaaa
    12061 ctttgatagg aggtcttgtt tcgtgaaaat atttatcaaa ttttctatac aagtgagctg
    12121 ttagccaggt tctttctatt ctttcaattt caatgaatgg attttttacc aatactcata
    12181 actgggaatt tttctgtcta aaaatagcga gatagatggt atttataaaa cactcaagac
    12241 agctagacta atatcattta aaacattatc ttcttttgag cgactgttgg ttaccaacat
    12301 agctaaattt cctgcatttt caaattgata gggttctgat ttagcattca caactaccaa
    12361 gaggtgttct ttgccgtgaa cttcatagat aaggcagccg ctatgttcaa tcgcagaatg
    12421 cacaaagaca tgatggtaaa tttcatcata gctagagtaa gaaaaggcac cagtttttgt
    12481 cttcaatcgg atgacttgac ggataaactc aatactgtct tgacgctcat taatcaagtt
    12541 ccagttcact tggttcacac tgtcaggagc attatagcta ttcatcgcac gctctctatc
    12601 atcatgggtc aactcaccat tttcaccagt cgcaaccagt ttggtacgac caaattcttg
    12661 accgatttcc ataaaggcca tcccctgcat gagcagattc atggctgtgg cagtttcgac
    12721 cttgcgcatg atttgctctg aactttggtc tggatgaagg gttgccaata aatcgtgaag
    12781 attgtaattg tcatgggctt ctacatagtt aagcacctga tttggatgtg tatagcttcc
    12841 taattcacga cttcctagga ttgctttagc tagaattggc tctgtcgcag caccactgac
    12901 aaaacctgac ttgataacac cataaacttc tcctcctttg acagcatcgc gctgattgtc
    12961 attaaagaaa ccaatatttg gcatctggta ggcattgtcc ttcttggcct tatcataagg
    13021 ggcaagacct gttcccatat cccatccttc tccatagagg ataatgttgg agtcgatttc
    13081 atccaagctt tgacgaatca tctgcatggt cttgacatca tgaatcccca tcaagtcaaa
    13141 acggaagccg tcaatattat attcctgcac ccagtataga agagaatcaa tcatatactt
    13201 gcgaaacatt tcgtgttcac tggctgtttc atttccaaca cccgttccat tctggaaggt
    13261 accatctgga ttcatacgat aatagtaatc agggactgtt gtttggaatg gtgcatcaac
    13321 aactgagaag gtatggttat agactacatc cataatgact ccaatacccg catcgtgata
    13381 agcttgaacc atcaccttca aatcacgaat gacctgagct ggatcatctg gattagttga
    13441 aaaactagtt tctggcgcgt tatagttttg tggatcataa ccccagttgt aggttacatt
    13501 tccatcctca tcgtattctt tatgacggtc tgcaattggt tgcaattgaa cataattgta
    13561 gcccagcttc ttgatgtaat caaaagcagt tgactggccg tattggttaa ctgttccagc
    13621 ctgagcagca cccaagaaag ttcctcgaag atgttcatct acacccgatg taggtgattt
    13681 agtcaaatca cgaatatgca tttcacagat aactgcctta catggatttt ccaagcgcca
    13741 agtagcctcc gaaccgtgct taacctcgaa gttttcaact tgcttttcta catggctcag
    13801 aatagctgaa cgtttgccat cagggctggt cgcgattgta taaggatcac gtgtcagtgt
    13861 ttggtgatga gggaattgga cttgatactg ataagtctta cctaccaaat cttcttcaac
    13921 atccaaactc cagacaccga ttgtattgtc cttatgatta taagagtagc tattgcctct
    13981 tttcatctca aaagtcttcc aaacgggtgc atcattagca gctgattcat aaacgacaac
    14041 ttgcacttct gtcgctgtag gtgaccagag ggaaaaatga gcctgattgt cctctacacg
    14101 gcaacccaat tctccttggt aaccccaatg atgatcaaaa ctagcactgt taatggcctt
    14161 atcaaaggca aaaggatttt gatttttata gaaaggactg gcaatagcag gattttcaga
    14221 gtaataaatc ctatcatcgc cttccaaaat ccagacttct gttaataggg gatagtgatt
    14281 aaaacggata gaatattctt tactagtttg acctgtatga accacaaaat tcaagctttc
    14341 tataacatgt gaacttgggt gttcaaagct aaataaagct ccaaaataat cttctttgta
    14401 ggttagcaaa tcaattcgtt gatcctgact ttttacaaag gagcaagtgt catattctcc
    14461 attcttacga tggtaatgaa tgcgcatagg gtagttatac attttttatt tttccttttt
    14521 actttgtttc tatttcacta ataaattttt gtcaatctcg tctcaattaa cagacatagt
    14581 catattctct aaactctgtt tttaaacgat ccattacaaa ctttctagcc atgcctcatc
    14641 tctgacctgg ataccaagtt cttgtgcttt ttgcagttta cttccagcgt ctgcacctac
    14701 cacgacgagg tcggtctttt tagaaacact acctgtcact ttggcaccca gactttcgag
    14761 tttactttta gcttctgagc gcttgagtcg ttccaatttt cctgtcaata ccacggtcaa
    14821 acctgacaag gccgcatccg ctactaccgt ctgtccttta tagttcagat tgaccccagt
    14881 ttctttcaat tctctgagca gaatttcaga gccttctgtc gcaaaataag tctgaagact
    14941 tttggcaatc acgccaccta gactttcaat actagccact tcctctgaat ctgcctgaga
    15001 cagattttca attgaatgga aatattgaag taaaagctga ctagccttgc ttccgacatg
    15061 acgaattccc aaaccaaata agagcttctc ggcagaattt tcctttgatg cttggatagc
    15121 ctgatacagt ttagcagcgg acttttcctt aaccccctct aaaaggagga aatcctcttc
    15181 ttgcaaacga taaatatccg ccacatcctt gactaaatta gcagcaaaaa gcttctcaac
    15241 aatagatgga ccaaggcctg taatattcat agtatcacga gaagcaaagt gaatcaagcc
    15301 ttccatgatt tgagcagggc aacgcggatt gatacaacgt agggccactt catcttcaaa
    15361 gtgcaacaag tcagagttac aacttggaca gtttgtaggg atatctagtt tttcttcaga
    15421 aacccgtttg gactctacca cacgtaaaac ggcagggatg atgtcaccag ccttatatac
    15481 aatgaccgta tcgtcttttc ggatatcttt ttcagcaata taatctacat tgtgcagggt
    15541 cgcacggcta acagtcgtac cggcaagttg tactggtgtt agattagcag ttggagttac
    15601 aacaccggta cggccaactg tccagtcaac tgataagagt tgagcttctt tttcttcagc
    15661 agggaacttg taggctactg cccactttgg agccttaacg gtaaaaccaa gttcttcttg
    15721 acttgctagg tcgttgacct tgattaccac tccatcaata tcgtaaggta gattttcccg
    15781 ttcctgtcct acttcttgga taaaattcca gatttcatct atgttttcag ccaagattcg
    15841 cttaggattg accacaaaac ctagttgttc taggtacttc aaaccctttt cttggctatc
    15901 acgagttgaa gggctggctt cttgatagag aaacgttgca agattacgct tggcaactac
    15961 tgctgtatcc aactgacgca gagttcctgc tgccgcatta cgaggattag caaattcagg
    16021 ctctccattt tcttggcgca cttggttaac ttggtcaaag gaagcgcgtg gcatgtaaca
    16081 ttccccacga actgtgatat ctagttcttc tggcaaagtc aaagggatgt ccttaacacg
    16141 cttgaggttt tctgtgatat tttcaccaat tgaaccatct ccacgtgtta ccccagcaac
    16201 caaaatcccc ttttcataag tcagcgagat agataagcca tcgattttca gctcacaaat
    16261 ataggtcgga tgagccactt ccttacgaac acgcgcatca aaagcatcta gctcctcacg
    16321 tgaaaaagca tcctgcaaac tataaagagg atactgatga ctgtattttt caaaaccatc
    16381 taaaaccttg ccaccaacac gatgagtcgg actgtctgct agcacttgct ctggataagc
    16441 agtttctaac tcgaccaact cacggtaaag gcggtcatac tcactgtctg aaaccgaggg
    16501 attatcgctg gtatagtact cagtcgcata gcgattgagc aaagcgacta actcattcat
    16561 tcttttattc ataagaccat tttaccataa aacaagccct cctcacaaac gagaagggcg
    16621 gaaaaaacac ttagtttgaa attatttttg aaactcaagc aaccttatat caatttttca
    16681 aaatgagttc gaacataaat aaacgatata caagacaaga tgataacacc acttccaatt
    16741 atcaggaaag aagagagatg tacacttggc aagactgtca taaatccttt tgcaataggc
    16801 ataaatagaa tagctaaggt aaaaattgta ctcagtactc tcccaagaaa ttcgctctca
    16861 accttggttt gtacttgagt aaaaaagtga atattaaaaa tcgtcataaa caattcacaa
    16921 actaaatttc cagaaaagga aagaaaagtt ggaagtggta atcccatcat aaaaactccg
    16981 acacctgtca aagccagtaa aatcaaaaga ttataaatat tagctttaat tttactagct
    17041 agaagagccc caatgatgga accaatagcc cccatagtta aaatacttgc ataggctcct
    17101 tctgacccgt aaagctgatt cgaaaaggga agtagaaatt caaaagctgc aaaaaagaaa
    17161 ttaacgctgg aagctaccag caaaaggaag aaaatttctt gctgatgcca gatatagtgt
    17221 aacccatcct tgatatctac aaaaatatct ctcccagtaa aagccttttt ctcttgaact
    17281 tttgcttcct cttttggaag gaaagccact agaacaaaag caatgaaaaa agtcagcgag
    17341 tctagcagta gcgtcatatg gagacttgca aactgtaaaa caaggaagga aagaacagga
    17401 gagctaacac ctacaacctg caaaaccagc tctaggcgag aattatagat cacaatctca
    17461 tctttctcca ccacttcagt tatgatagct ttattggctg tgcgagaaaa ggcaaaagca
    17521 atagcctgca caatgttagc aacaatcaaa gcgccaatca tccagctatc attccttatg
    17581 aaagaaatag ccagacaaag aatcccacaa acaagatctg ccgtcattaa aatcttacga
    17641 cgagaaaaac ggtctgaaat aactccgcca aagggattga cgagaataga tgtgacgagc
    17701 tcagaaatct gatacattcc taaaactgtc tgtcctatag tccccataga agccaaccag
    17761 acactatttc cataatcata gagcatattt cccattttat tgatagcccc acggctaatc
    17821 aactgcactg catagcgatt catattaaag ctcctctcaa attttgaaac tattgtatca
    17881 aaaccgaaag gagcttttta ttttttccct tatttgggaa aattaacttt tgacaaattt
    17941 ttcgtagtgt tcctgataat aggctacttg ctctggaaga cctaacacat caaaaatatg
    18001 tatggcctct tgcatctgct tacagccttc tttacactgt cctttttgat ataaggcaaa
    18061 accttttaaa taatggaaaa cattacgctc ataaagctta atacctttgt caataatctt
    18121 ctctgtataa gcctcaaaat agttggcatt ataaaaagaa gaatgctcta aacaatgctg
    18181 gtaacaattg agggccaaaa tcaacactaa tctcttatgg cgactaatct cttggtaaaa
    18241 ttcctccctc tccataactt ctctaccaat ccgagtgaca taatccacat cgtagaaact
    18301 atagaggtta ccgaaaagaa tcaactcata catggtccat tcttctgttt tgaagagata
    18361 atctgctacc ttatccaaat catcctgctt catatcataa ctcgcatctc tttgacaaat
    18421 cagaccctgt agcaaaatcc agttcagctc aaaataaagg ggagtcgtcg aactcttaga
    18481 cttttcaagt tgttctcttt gaagcttttg aaaacctgca atatcgtttg aatagtaaag
    18541 tgggataatc tgtgccatca tagacacatg ttcatgatta tgaaaattcc ttgccttatc
    18601 catgaaattt tcgattgtta catgaatgtt atccaaaatc tcaaagaaac gggagactgc
    18661 caggtcagac tccccaagct caaagcgaga taactgagag gtagagcagg attcgcctgc
    18721 tgcttccttt aaagaataat ttccacttgt tcgaaattca cgaaatactt ttccaagatg
    18781 ttccatcttt acacctgctc tgataattct tcccactcaa gcatagcttc ttcctgacga
    18841 tggctgattt tgtccagctc agcctgtaat tccatgagtt tgtcggcatc gtttgtttcc
    18901 aacatttgtt cagaaatgac ttggctttga ctttctagct cttcaatttc agcttctaga
    18961 ctttcgattt gtcgcatgag tttgcgaact tctttttgac tttctttctg ggcctgatag
    19021 tcattgactg gacttgcttc ctttgcttga ttgctagttg aagcttcctc agtctgactc
    19081 atttctgctg ttgctttctt ctcaacatag tagtcgtaat ctccaaggta gagagttgaa
    19141 ccattctcag acaattccaa aacatgagtt gccacacgat tgataaagta acgatcatga
    19201 ctgacaaaaa gcaaggtacc atcaaagtca atcaaggcat tttctagcac ttccttacta
    19261 tcaatatcca agtggttggt cggctcatcc agaatcaaaa agttattgtt ttccatagac
    19321 aatttagcta aaagcaaacg agctttttcg ccaccagata gcatgccgac tgatttttta
    19381 acatcatctc ctgagaaaag gaaggctcca agacggttgc ggatttcaac ttctggtgtc
    19441 agtttgaaat cattccagag ttcatccagc accgtattac ttggtgtcag cttgctttgg
    19501 gtttggtcat agtaaccaac ctcaacatta gcgccaaagc gcttttctcc cttgataaaa
    19561 ggaatctggt ccacaataga cttgataaag gttgacttgc cgataccatt tggaccaacg
    19621 atagcgacag cattcatctt acgaagatct aggttgatag gttgtgacaa aacttccccg
    19681 tcataaccaa tagcagtatt ttcaacagtc aaaacaacat tgcccgacgt tttttcagac
    19741 tggaaggtca tgttggctgc tttcttgcca gcttcaggct tgtccaaacg ctccattttt
    19801 tctagttgtt tacggcgaga ttgagcacgt ttggtcgttg aagcacgaac tagattgcga
    19861 ttgacaaagt cttccagagc agcgatttcc ttctgttgct tttcatagtt ttttgcctca
    19921 gtagctagct tttgctcctt caactcaaca aaacgagagt aattccccac atagcgatcc
    19981 aaggaatgct tggtcaaatc tagcgtaatt gtcgcaacct tgtccaagaa ataacggtcg
    20041 tggctgacga taatgagggc accgctatag tttactaagt aattctctag ccaggagatg
    20101 gtttcaatat ccaagtggtt agttggctcg tccaagacca agagattggg cttttcaagg
    20161 agcattttag ctagagccaa acgagtattt tgaccaccag aaagctcagc aattttcatc
    20221 tgccacatag actcgtcaaa cttgaatcca ttcaaaatcg ctcgaatatc agcttcatag
    20281 gtaaagccac ctgcttggcg aaaattttca gataagcggt cataatctga catcagttta
    20341 tccaaatcct caccagactt ttcacccatc tccagctcca tctgacgcag ttgtttatct
    20401 gtccgacgta agtcatcaaa gacatgaagc atctcatcat agatggtatt ttcagactca
    20461 aaacggctat cttgagctag gtaagacaga gaaatatctt ttttcttatt gatttctcca
    20521 ctagttggct cctcttctcc aactaaaatc ttcaaaagag tagacttacc tgcaccattt
    20581 ttcccaacaa gggcaatccg atctcgttca tcaacctgca ggttgatatt atcgaaaaga
    20641 acctctcctg caaaagaacg ttcaatttta ttagcttgta aaataatcat acaagtagta
    20701 tagcatgttt ccctaaggca ttcaagataa tcgtaagtct tttagtacaa cttttataac
    20761 ataaaataaa ctaaattatg tatattttat attagattcc ttcactatct tgttggattt
    20821 tctaaccagc taatcttgtt tcaaatagtt atcgcacaag cctattattt aattcttttc
    20881 attatttacg tacgc
//
LOCUS       DAVHBD010000043        20276 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000043 DAVHBD010000000
VERSION     DAVHBD010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.043"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            21..419
                     /locus_tag="VVK04_001677"
     CDS             21..419
                     /locus_tag="VVK04_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990309.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(616..1536)
                     /gene="cysK"
                     /locus_tag="VVK04_001678"
     CDS             complement(616..1536)
                     /gene="cysK"
                     /locus_tag="VVK04_001678"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU3990310.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEDAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVIIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1821..2456)
                     /locus_tag="VVK04_001679"
     CDS             complement(1821..2456)
                     /locus_tag="VVK04_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU3990311.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2512..3810
                     /locus_tag="VVK04_001680"
     CDS             2512..3810
                     /locus_tag="VVK04_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU3990312.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3807..4469
                     /locus_tag="VVK04_001681"
     CDS             3807..4469
                     /locus_tag="VVK04_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU3990313.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4549..5097
                     /gene="raiA"
                     /locus_tag="VVK04_001682"
     CDS             4549..5097
                     /gene="raiA"
                     /locus_tag="VVK04_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU3990314.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5233..7206
                     /locus_tag="VVK04_001683"
     CDS             5233..7206
                     /locus_tag="VVK04_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU3990315.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAIGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7203..7655
                     /gene="rplI"
                     /locus_tag="VVK04_001684"
     CDS             7203..7655
                     /gene="rplI"
                     /locus_tag="VVK04_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU3990316.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7699..9051
                     /gene="dnaB"
                     /locus_tag="VVK04_001685"
     CDS             7699..9051
                     /gene="dnaB"
                     /locus_tag="VVK04_001685"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU3990317.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            9053..9319
                     /locus_tag="VVK04_001686"
     CDS             9053..9319
                     /locus_tag="VVK04_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990318.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9408..10754
                     /gene="cbpD"
                     /locus_tag="VVK04_001687"
     CDS             9408..10754
                     /gene="cbpD"
                     /locus_tag="VVK04_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU3990319.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10837..10939
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11010..11300
                     /locus_tag="VVK04_001688"
     CDS             11010..11300
                     /locus_tag="VVK04_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU3990320.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11263..12021
                     /locus_tag="VVK04_001689"
     CDS             11263..12021
                     /locus_tag="VVK04_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990321.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            12060..13067
                     /locus_tag="VVK04_001690"
     CDS             12060..13067
                     /locus_tag="VVK04_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU3990322.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            13067..13795
                     /locus_tag="VVK04_001691"
     CDS             13067..13795
                     /locus_tag="VVK04_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990323.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13914..14372
                     /locus_tag="VVK04_001692"
     CDS             13914..14372
                     /locus_tag="VVK04_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU3990324.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            14374..16806
                     /locus_tag="VVK04_001693"
     CDS             14374..16806
                     /locus_tag="VVK04_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU3990325.1"
                     /translation="MNYSKALNECIESAYMVAEHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIATLRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDVKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENIEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            17127..17780
                     /gene="rr06"
                     /locus_tag="VVK04_001694"
     CDS             17127..17780
                     /gene="rr06"
                     /locus_tag="VVK04_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU3990326.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDEITQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17777..19117
                     /gene="hk06"
                     /locus_tag="VVK04_001695"
     CDS             17777..19117
                     /gene="hk06"
                     /locus_tag="VVK04_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU3990327.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINNIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            19212..19739
                     /locus_tag="VVK04_001696"
     CDS             19212..19739
                     /locus_tag="VVK04_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU3990328.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19818..>20276
                     /locus_tag="VVK04_001697"
     CDS             19818..>20276
                     /locus_tag="VVK04_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEU3990329.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEEVGGRN
                     TPTVTSSGQDISKKYADEVESHLKKILSEIQTQLDRKRHTKTVALINELQNIKKTYLY
                     NLNVLKEKSELPSKIKAKLEVAFDQFKKDTLKPGEKVAEAEKKVAEAKKKA"
BASE COUNT         6282 a         3327 c         4598 g         6069 t
ORIGIN      
        1 ataatcatct ggataagctt gtgaaatctc ctattcctaa agccccttta gcgcataact
       61 ttggctcagc ttctattatc gctcacacca tccatcagaa gtttaatctg aaggtaccca
      121 attatcgcca agaagaagat tgggctagga tgggtttacc aatcacacgt aaggaaatct
      181 ctaatcggca tatcaagacg agtcaatact atttggagcc cctttataac ctcttgcgag
      241 agagactatt gactcagccc ttacttcatg cggatgaaac ttcttatagg gtgctagaga
      301 gtgatagtca gctgacttac tattggactt ttttgtctgg gaaagctgag aaacaaggga
      361 ttacgcttta ccatcatgtc ctaatcgatt tgttcatatc ttatttcaat ccattataaa
      421 tagtgagaaa tatctatcct atcttctaga atgtcttcca aacgtggaaa ctctcgtaaa
      481 caaagaggtt ttagaggcct atttaccatg gactaaagtt gtacaagaaa agtgcaaata
      541 agaaatctcc agattaggaa ctatccgtga gttctctagt ctggagattt ttcaatagac
      601 ttcgttattg gacggttaca attcataaag tgctgtagag agataacgtt caccgttatc
      661 tggtgctagg gcaaggactt ttttacctgt acctaatttt ttggcaacct cgatggctcc
      721 gtagatagct gcagctgagg aaatccctac aaggaagcct tcttttccac caatttcacg
      781 tccgagtgca agagcgtcat ctgatgttac acgaacgata ccatcatagg ctttagtatc
      841 aagtgtatca ggaataaatc cagctgagat accttgaatt ttgtgaggac caggtttttc
      901 accagataga atagcagatt catctgcttc tactgcaaaa acttgaatgt tagaattttc
      961 tgatttgagt gcatgagaaa caccagaaat cgttccacca gtacctactc cagcaacaaa
     1021 ggcatctaat ccatctttac cgaaagcagc tagtatctca gctcctgttg ttctttcgtg
     1081 tacttctgga ttagctggat tgtcaaattg aagaggaagg aaaccatcac gttcagcagc
     1141 gatttcttga gccttagcaa tagcaccttt cattccctcg ctaccaggag ttaggacgag
     1201 ttcagcacca taagcttgga taattttacg tcgttctaca ctcatagttt caggcataac
     1261 gatgatgact ttataccctt tagcagcacc tacccatgaa agtccaatac cggtgtttcc
     1321 acttgttgct tcaacaatag tagaaccaag tttcagaata ccatcttgtt cagctttttc
     1381 aatcatgcta agggcaatac ggtcttttac agatgaacca ggattaaatg cttcaagctt
     1441 tatatagacg tctgcagcat cttctggcac gatgttgtta agtttaacaa tcggtgtttg
     1501 accgattaat tcagtaatgt tgttataaat agacatatga atacctcttt gtataagata
     1561 tctttagtat aacgctatcc ataccatttg taaaatatag aaatcctatc gaagcgatag
     1621 gatttctata tatcatagat caaagtcatt aattttcaag tgattgcgtt cagttaattc
     1681 tagtaaatag gtgtgaagga aaacgatatc aggtttcgtt tgaattgctt cattttctag
     1741 tatattttgg tacgcatctt tttattttgc tcgctaaagt agttgtgaga atgtcaacga
     1801 aacgctgtat tattcattgt ttacactaag tttacaggaa cttcaacctc tcgtaaacct
     1861 tggtcagtta aagtgacttt tccattaaaa aactccacaa gtgcagcttt aatagtttct
     1921 ttttcttctt tatcaacata aatcatcgta tcgacttgat ctgtaaagtt tgtatccagc
     1981 tccatgagat catgttcttt aaggaagtta ctgtactctt ggtactgagc ataagacatt
     2041 tgaatagcaa tgccagcctg ttcttttatt tcaataatac caatttcttt gacagctaag
     2101 gcgacactgc cggcgtaagc acgaattagt cctccagcgc ctagtttaat accaccaaag
     2161 tagcgtgtca cgaccacaca gacattggtg agattgtgat tttctagtac cccaagcatg
     2221 ggaacaccag cagtaccact aggctcacca tcatcacttg tacgtttaat ttcactacgt
     2281 tctccaataa taaaggcaga gcagttatgt gtcgctttgt agtgttcttt tttgatggca
     2341 gtaatgaagt cacgagcctc ttcttcgcta taaacacgct tggcatggca gataaagcga
     2401 gattttttga tttcttcttg gacttggccg tcctctttaa ttgtcctaaa ttccatgatt
     2461 taattgtact aaaaaatcat ctaaagtgct agtttttacg aataaagaag tatgaaagta
     2521 aatttagatt atctcggtcg tttatttact gagaatgaat taacagaaga agaacgtcag
     2581 ttggcggaga aacttccagc aatgagaaag gagaagggga aacttttctg tcaacgttgt
     2641 aatagcacta ttctagaaga atggtatttg cccatcggtg cttactattg tcgagagtgc
     2701 ttgctgatga agcgagtcag aagtgatcaa actttatact attttccgca ggaggatttt
     2761 ccgaagcaag atgttctcaa atggcgcggc caattaactc cttttcaaga gaaggtgtca
     2821 gagggactgc ttcaagcagt agacaagcaa aagccaacct tagttcatgc ggtaacagga
     2881 gctggaaaga cagaaatgat ttatcaagta gtggctaaag tgatcaatgc gggtggtgca
     2941 gtgtgtttgg ctagtcctcg catagatgtt tgtttggagc tgtacaagcg cctgcaacag
     3001 gatttttctt gcgggatagc tttgctacat ggagaatcgg aaccttattt tcgaacacca
     3061 ctagttgttg caacaaccca tcagttattg aagttttatc aagcttttga tttgctgata
     3121 gtggatgaag tagatgcttt tccttatgtt gataatccca cgctttacca tgctgtcaag
     3181 aatagtgtaa aggagaatgg attgagaatc tttttaacag cgacttcgac caatgagtta
     3241 gataaaaagg tccgtttagg agaactaaaa agactgaatt taccgagacg gtttcatgga
     3301 aatccgttga ttattccaaa accaatttgg ttatcggatt ttaatcgcta cttagacaag
     3361 aatcgtttgt caccaaagtt aaagtcctat attgagaagc agagaaagac agcttatccg
     3421 ttactcattt ttgcttcaga aattaagaaa ggggagcagt tagaagaaat cttacaggag
     3481 caatttccaa atgagaaaat tggctttgta tcttctgtaa cagaggatcg attagagcaa
     3541 gtacaagctt ttcgagatgg agaactgaca atacttatca gtacgacaat cttggagcgt
     3601 ggagttacct tcccttgtgt ggatgttttc gtagtagagg ccaatcatcg tttgtttacc
     3661 aagtctagtt tgattcagat tggtggacga gttggacgaa gcatggatag accgacagga
     3721 gatttgcttt tcttccatga tgggttaaat gcttcaatca agaaggcgat taaggaaatt
     3781 cagatgatga ataaggaggc tggtctatga agtgcttgtt atgtgggcag actatgaaga
     3841 ctgttttaac ttttagtagt ctcttacttc tgaggaatga tgactcttgt ctttgttcag
     3901 actgtgattc tacttttgaa agaattgggg aagagaactg tccaaattgt atgaaaacag
     3961 agttgtcaac aaagtgtcaa gattgtcaac tttggtgtaa agaaggagtt gaagtcagtc
     4021 atagagcgat ttttacttac aatcaagcta tgaaggattt tttcagtcgg tataagtttg
     4081 atggagactt cctgttaaga aaagttttcg cttcattttt aagtgaggag ttgaaaaagt
     4141 acaaagagta tcaatttgtt gtaattcccc taagtcctga tagatatgct aatagaggat
     4201 ttaatcaggt tgagggcttg gtagaggcag caggctttga gtatctggat ttattagaga
     4261 aaagagaaga gagagccagt tcttctaaaa atcgttcaga gcgcttgggg acagaacttc
     4321 ctttctttat taaaagtgga gttactattc ctaaaaaaat cctacttata gatgatatct
     4381 atactacagg agcaactata aatcgtgtta agaaactgtt ggaagaagct ggtgctaagg
     4441 atgtaaaaac attttccctt gtaagatgag gaaaaaattt gcaaaaatag aatgaaagcg
     4501 ttataataaa atcataaaaa caaaaatgtt tagaaagaag gtactcatat gattaaatat
     4561 agtatccgtg gtgaaaacct agaagtaaca gaagcaattc gtgattatgt agtttctaaa
     4621 ctcgaaaaga tcgaaaagta cttccaacca gaacaagagt tggatgcccg aattaactta
     4681 aaagtttatc gtgaaaaaac ggctaaagtg gaagtaacga ttccgcttgg atctattact
     4741 ctccgcgcag aagatgtatc tcaagatatg tatggttcaa ttgaccttgt aactgataaa
     4801 attgaacgtc agattcgtaa aaataaaaca aaaatagagc gtaaaaataa aaataaggta
     4861 gcaactggtc aattatttac agatgctttg gtggaagatt caaatattgt ccagtctaaa
     4921 gttgttcgtt caaaacaaat tgatttaaaa ccaatggatt tggaagaagc aattctacaa
     4981 atggatttat tggggcatga tttctttatc tatgtggatg ttgaagatca gacaaccaat
     5041 gtgatttatc gtcgtgagga tggcgaaatt ggtttgttag aggttaaaga atcttaattt
     5101 caatatgtgt aaaggtaggt ttactgaatt gtaaactacc tttttcttat aattgataga
     5161 attactgatt acacttttaa aaagtcgctt tttgaggggt attatggtat aatgggtgcc
     5221 aagaggtttt gaatgaaaaa attttatgta agtccaattt ttcctattct agtaggattg
     5281 attgcgtttg gagtcttatc cactttcatt atttttgtta ataataatct gttgacggtt
     5341 ttaattttgt ttctttttgt aggaggctat gtttttttat ttaagaaact gagagtgcat
     5401 tatacaagga gtgatgtaga acagatacag tatgtaaacc accaagcgga agaaagtttg
     5461 acagctctat tggaacagat gcctgtaggt gttatgaaat tgaatttatc ttctggagag
     5521 gttgagtggt ttaatcccta tgctgaattg attttgacca aggaagatgg tgattttgat
     5581 ttagaagctg ttcaaacgat tatcaaggct tcagtaggaa atccgtctac ttatgccaag
     5641 cttggtgaga agcgttatgc tgttcatatg gatgcttctt ccggtgtttt gtattttgta
     5701 gatgtatcca gggaacaagc cataacagat gaattggtaa caagtagacc agtgattggg
     5761 attgtctctg tggataatta tgatgatttg gaggatgcaa cttctgagtc agatattagt
     5821 caaatcaata gttttgtagc taattttata tcagagtttt cagaaaaata catgatgttt
     5881 tctcgtcggg taagtatgga tcgattttat ctatttactg actacacggt gcttgagggc
     5941 ttgatgaatg ataaattttc tgttattgat gctttcagag aagagtcgaa acagagacag
     6001 ttgcccttga ccttaagtat gggattttct tatggcgatg gaaatcatga tgagataggg
     6061 aaagttgctt tgctcaattt gaacttggct gaagtacgtg gtggcgacca ggtggttgtt
     6121 aaggaaaacg acgaaacgaa aaatccagtt tattttggtg gtgggtctgc tgcttcaatc
     6181 aagcgtacac ggactcgtac gcgcgctatg atgacagcta tttcagataa gattcggagt
     6241 gtagatcagg tttttgtagt cggtcacaaa aatttagaca tggatgcttt gggctctgct
     6301 gtaggtatgc agttgttcgc cagcaatgtg attgaaaata gctatgctct ttatgatgaa
     6361 gaacaaatgt ctccagatat tgaacgagct gtttcattca tagaaaaaga aggagttacg
     6421 aagttgttgt ctgttaagga tgcaattggg atggtgacca atcgttcttt gttgattctt
     6481 gtagaccatt caaagacagc cttaacatta tcaaaagaat tttatgattt atttacccaa
     6541 accattgtta ttgaccacca tagaagggat caggattttc cagataatgc agtcattact
     6601 tatatcgaaa gtggtgcaag tagtgccagt gagttggtaa cggaattgat tcagttccag
     6661 aattctaaga aaaatcgttt gagtcgtatg caagcaagtg ttttgatggc tggtatgatg
     6721 ttggatacta aaaatttcac ctcgcgagta actagtcgga catttgatgt tgctagctat
     6781 ctcagaacgc gcggaagtga tagtattgct atccaggaaa ttgctgcgac agattttgaa
     6841 gaatatcgtg aggttaatga acttatttta caggggtgta aattaggttc agatgtacta
     6901 atagcagagg ctaaggacac gaaatgctat gatacagttg ttattagtaa ggcagcagat
     6961 gccatgttag ccatgtcagg tattgaagcg agttttgttc ttgcgaagaa tacacaagga
     7021 tttatctcta tctcagctcg aagtcgtagt aaactgaatg tacaacggat tatggaagag
     7081 ttaggcggtg gaggccactt taatttggca gcagctcaaa ttaaagatgt aaccttgtca
     7141 gaagcaggtg aaaaactgac agaaattgta ttaaatgaaa taaaggaaaa ggagaaagaa
     7201 gaatgaaagt aatcttttta gcagatgtta aaggaaaagg taaaaaaggc gaaattaagg
     7261 aagtaccaac agggtatgcg caaaactttc ttatcaaaaa gaatctagcc aaagaagcga
     7321 ctgctcaagc tgtaggtgaa cttcgtggta aacaaaaatc ggaagaaaaa gctcacgctg
     7381 agatgattgc agaaggaaaa gcaattaaag cacaacttga agcagaagaa actgttgtag
     7441 aatttgttga aaaagttggt ccagatggtc gtacctttgg ttctattacc aataagaaga
     7501 ttgcagaaga attgcaaaag caatttggaa ttaagattga taaacgtcat attcaagtac
     7561 aagctccgat tcgagcggtt ggtttgattg atgtgccagt gaaaatctat caagatatca
     7621 caagtgtaat caatcttcgt gtgaaagaag gataagttta caccttcttg acaagattgt
     7681 aaaaggaagg gaagtctgat ggcagaagta gaagagttac gagtacaacc tcaagatatc
     7741 ttagctgagc aatccgtttt aggggctatc tttattgatg agagtaaact tgtttttgtg
     7801 cgagaataca ttgagtctcg ggactttttt aagtatgccc atcgtttgat tttccaagcc
     7861 atggtcgatt tatccgatcg tggtgatgcc atagatgcaa caacggttcg tactatcctt
     7921 gataatcaag gtgatttaca gaatattggt ggcttgtctt acttggttga gattgtcaat
     7981 tctgtgccaa cttctgctaa tgcggagtat tatgctaaga ttgttgcaga aaaagcaatg
     8041 ctacgtcgtt taattgccaa gttgacagag tctgtcaacc aagcttacga agcgtcacaa
     8101 ccagctgatg aaattattgc tcaggcagaa aaagggctga ttgatgtcag tgaaaatgca
     8161 aatcgaagcg ggtttaagaa cattcgagat gtgttgaatc tcaactttgg aaatctggaa
     8221 gctcgctcgc aacaaacgac cgatattaca ggtattgcga caggttatcg tgatttggat
     8281 catatgacaa caggacttca tgaggaggag ttgattatct tagcagctcg tccagcagtt
     8341 ggtaagacag catttgcctt gaatatcgct cagaatattg ggactaagtt ggacaaaacg
     8401 gttgctattt tttcactcga aatgggtgcg gaaagcttgg tagaccgtat gttagctgca
     8461 gaaggcttgg tggagtcaca ttctatccgt acagggcaat tgacagatga ggagtggcaa
     8521 aaatatacta ttgctcaggg taatctagct aacgccagta tctatatcga tgatacgcca
     8581 ggtattcgga ttacagagat tcgttctcgt tctcgtaaat tggctcaaga aactggaaat
     8641 cttggtttga ttttgataga ctatttgcaa cttatcacgg gaactggtcg agaaaatcgt
     8701 caacaagaag tttctgaaat ttctcgtcag ttgaaaatac tagccaagga attgaaggtt
     8761 ccagtaatcg ctctgagtca gctttctcgt ggtgtagaac aacgtcagga caagagaccg
     8821 gtcttgtctg atattcgtga atctgggtct attgagcagg acgctgatat cgtagctttt
     8881 ctctatcgcg atgactacta tgaacgtggt ggtgaagaag aggagggtat cccaaataat
     8941 aaggtggaag ttattatcga gaaaaaccgt agtggagctc gtggaacagt ggaattgatt
     9001 ttccaaaaag aatacaataa attttcaagt atctcaaaga gggaggcata agatgtcaga
     9061 tgcatttaca gatgtagcca agatgaaaaa aatcaaagaa gaaatcaagg cacatgaggg
     9121 acaagtcgta gaaatgactt tggagaatgg tcgtaagcgc caaaaaaata gattgggtaa
     9181 gctaattgaa gtttatccat ccctatttat tgtggagttt ggggatgtgg aaggagataa
     9241 acaagttaat gtttacgttg aatcctttac ttactcagat attcttacag aaaagaattt
     9301 gattcattat cttgactaaa gtgagaaatt ttctcacttt ttcttttttc tccgaataat
     9361 ttaggtgaag gcaatcatcg ctttatatta ttttttaagg aggaagaatg aaaattttac
     9421 cgtttatagc aagaggaaca agttattact tgaagatgtc agttaaaaag cttgttcctt
     9481 ttttagtagt aggattgatg ctagcagctg gtgatagtgt ctatgcctat tccagaggaa
     9541 atggatcgat tgcgcgtggg gatgattatc ctgcttatta taaaaatggg agccaggaga
     9601 ttgatcagtg gcgcatgtat tctcgtcaat gtacttcttt tgtagccttt cgtttgagta
     9661 atgtcaatgg ttttgaaatt ccggcagctt atggaaatgc gaatgaatgg ggacatcgtg
     9721 ctcgtcggga aggttatcgt gtagataata caccgacgat tggttccatt acttggtcta
     9781 ctgcaggaac ttatggtcat gttgcctggg tgtcaaatgt aatgggagat cagattgaga
     9841 ttgaggaata taactatggt tatacagaat cctataataa acgaattata aaagcaaaca
     9901 cgatgacagg atttattcat tttaaagatt tggatggtgg cagtgttggg aatagtcaat
     9961 cctcaacttc aacaggcgga actcattatt ttaagaccaa gtctgctatt aaaactgaac
    10021 ccctagttag tgcaactgtg attgattact attatcctgg agagaaggtt cattatgatc
    10081 aaattctcga aaaagacggc tacaagtggt tgagttatac tgcctataat ggaagctatc
    10141 gttatgttca attggaggct gtgaataaaa atcctctagg tcattctgtt ctttcttcaa
    10201 caggtggaac tcattatttt aagaccaagt ctgctatcaa aactgaaccc ctagttagtg
    10261 caactgtgat tgattactat tatcctgggg agaaggttca ttatgatcag atacttgaaa
    10321 aagacggcta caagtggttg agttatacgg cttataacgg aagtcgtcgc tatatacagc
    10381 tagagggagt gacttcttca caaaattatc agaatcaatc aggaaatatc tctagctatg
    10441 gatccaataa tagttcaact gtcggttgga agaaaataaa tggtagttgg tatcatttca
    10501 aatcaaatgg ttctaaatca acaggatggc tgaaagatgg ttctagctgg tattatttga
    10561 aattatctgg tgaaatgcag acaggatggt taaaggagaa tggctcgtgg tattatctgg
    10621 gtagttcagg ggcaatgaaa acaggctggt atcaggtctc tggtaagtgg tattattctt
    10681 actcttcagg cgccttagct gttaatacga cggtggatgg ctacagagta aacagtgatg
    10741 gagaacgagt atagaaaatt ggagtaggag aaatttcctg ctcttttctg taagcagttt
    10801 ccttgacatt tttcttattt tgcgctatca tatatacata taatatatgg gagtctgtgt
    10861 acagtctgag aggaagtgtt aaacttcgac cgcacctgat ctgggtaatg ccagcggagg
    10921 gaacgatact tagtctaatt ttgcaccttt tccatgtatg gtaaaggttt ttcttttttt
    10981 taaaaggaaa acgagaagag gaggttctta tgaaagcaag cattgccttg caagttttac
    11041 ccctagtaca ggggattgat cggatagctg ttattgatca ggtcattgct tatctgcaaa
    11101 ctcaagaagt gccgatggta gtgacaccat ttgaaacggt cttggaaggg gagtttgatg
    11161 agcttatgcg cattctaaaa gaagcgctgg aagtggcagg gcaggaggca gacaatgtct
    11221 ttgccaatgt caaaataaat gtaggagaga ttttaagtat tgatgagaaa cttgagaagt
    11281 atactgagac gacacattag tctattgggc tttctcggag tcttgtcaat ctggcagtta
    11341 gcaggttttc ttaaactgct ccccaagttt atcctgccga cacctcttga aattctccag
    11401 ccctttgttc gtgacagaga atttctctgg caccatagct gggcgacctt gagagtggct
    11461 ttactggggc tgattttggg agttttgatt gcctgtctta tggctgtact catggatagt
    11521 ttgacttggc tcaatgacct gatttaccct atgatggtgg tcattcagac cattccgacc
    11581 attgccatag ctcctatcct ggtcttgtgg ctaggttatg ggattttgcc caagattgtc
    11641 ttgattatct taacgacaac ctttcccatc atcgtcagca ttttggacgg ttttaggcat
    11701 tgcgacaagg atatgctgac tttgtttagt ctgatgcggg ccaagccttg gcaaatcctg
    11761 tggcatttta aaattccagt cagcctgccc tacttttatg ctggtctgag ggtcagtgtc
    11821 tcctacgctt ttatcacaac agtggtatct gagtggttgg gaggctttga ggggcttggt
    11881 gtttatatga ttcagtccaa gaaattgttt cagtatgata ccatgttcgc tattattatt
    11941 ctggtatcga ttatcagcct tttgggtatg aagttggtcg atattagtga aaaatatgtt
    12001 attaaatgga aacgttcgta gaattagaat gtttctgaaa aagaaaagag gaaatcaaaa
    12061 tgaagaaaac atggaaagtg tttttaacgc ttgtaacagc tcttgtagct gttgtgcttg
    12121 tggcctgtgg tcaaggaact gcttctaaag acaacaaaga ggcagaactt aagaaggttg
    12181 actttatcct agactggaca ccaaatacca accacacagg gctttatgtt gccaaggaaa
    12241 aaggttattt caaagaagct ggagtggatg ttgatttgaa attgccacca gaagaaagtt
    12301 cttctgactt ggttatcaac ggaaaggcac catttgcagt gtatttccaa gactacatgg
    12361 ctaagaaatt ggaaaaagga gcaggaatca ctgccgttgc agctattgtt gaacacaata
    12421 catcaggaat catctctcgt aaatctgata atgtaagcag tccaaaagac ttggttggta
    12481 agaaatatgg gacatggaat gacccaactg aacttgctat gttgaaaacc ttggtagaat
    12541 ctcaaggtgg agactttgag aaggttgaaa aagtaccaaa taacgactca aactcaatca
    12601 caccgattgc caatggcgtc tttgatactg cttggattta ctacggttgg gatggtatcc
    12661 ttgctaaatc tcaaggtgta gatgctaact tcatgtactt gaaagactat gtcaaggagt
    12721 ttgactacta ttcaccagtt atcatcgcaa acaacgacta tctgaaagat aacaaagaag
    12781 aagctcgcaa agtcatccaa gccatcaaaa aaggctacca atatgccatg gaacatccag
    12841 aagaagctgc agatattctc atcaagaatg cacctgaact caaggaaaaa cgtgactttg
    12901 tcatcgaatc tcaaaaatac ttgtcaaaag aatacgcaag cgacaaggaa aaatggggtc
    12961 aatttgacgc agctcgctgg aatgctttct acaaatggga taaagaaaat ggtatcctta
    13021 aagaagactt gacagacaaa ggcttcacca acgaatttgt gaaataatga cagaaattag
    13081 actagagcac gtcagttatg cctatggtca ggagaggatt ttagaggata tcaacctaca
    13141 ggtgacttca ggcgaagtgg tttccatcct aggcccaagt ggtgttggaa agaccaccct
    13201 ctttaatcta atcgctggga ttttagaagt tcagtcaggg agaattgtcc ttgatggtga
    13261 agaaaatccc aaggggcgcg tgagttatat gttgcaaaag gatctgctct tggagcacaa
    13321 gacggtgctt ggaaatatca ttctgcccct cttgattcaa aaggtggata aggcagaagc
    13381 tatttcccga gcggataaaa ttcttgcgac cttccagctg acagctgtaa gagacaagta
    13441 tcctcatgaa cttagcggtg ggatgcgcca gcgtgtagcc ttactccgga cctacctttt
    13501 tgggcacaag ctctttctct tagatgaggc ctttagcgcc ttggatgaga tgacaaagat
    13561 ggaactccac gcttggtatc ttgagattca caagcagttg cagctaacaa ccctgatcat
    13621 cacgcatagt attgaggagg ccctcaatct cagcgaccgc atctatatct tgaaaaatcg
    13681 ccctgggcag attgtttcag aaattaaact agattggtct gaagatgagg acaaggaagt
    13741 ccaaaagatt gcctacaaac gtcaaatctt ggcagaatta ggcttagata agtagaaaaa
    13801 tagggagttg gtgaagatta tcctttacca gcgccctttt tcttttaaaa atgagaaaat
    13861 ttcggtataa tagtcaaaca aggtcaaggt ttaaagagag aggtgggttt gttatgagat
    13921 ttaaaaatac atcggatcat attgaggcct acatcaaggc gattttagat caatctggta
    13981 tcgtggagtt gcaacggagt cagttggcag atacctttca ggttgttcct agtcagatta
    14041 actacgtgat caagacacgc tttacggaaa gtagaggcta cttggttgaa agtaagcgtg
    14101 gtggcggagg ctacattcgt ataggacgga ttgagttttc tagtcatcat gaaatgctcc
    14161 gggagctgct ttactcgatt ggtgagcgag tcagtcaaga aatttatgag gatattctcc
    14221 agcttttggt tgagcaggaa ttgatgacca agcaggagat gaatttgcta gaatcagtag
    14281 ctttggatcg cgttttagga gaagaagctc cagttgttcg agcaaacatg ctacgtcaga
    14341 tcatacaaga ggtagataga aaagggaagt aagatgaact attcaaaagc attgaatgaa
    14401 tgtatcgaaa gtgcctacat ggttgctgaa cattttggag ctcgttatct agagtcttgg
    14461 cacttgttga ttgccatgtc taatcacagt tatagtgtag caggggcaac tttaaatgat
    14521 tatccgtatg agatggaccg tttagaagag gtggctttgg aactgactga aacggactat
    14581 agccaggatg aaacctttac ggaattgccg ttctcccgtc gtttgcaggt tctttttgac
    14641 gaagcagagt atgtagcgtc agtggtccat gctaaggtgc tagggacaga gcacgtcctc
    14701 tatgcgattt tgcatgatgg caatgccttg gcaactcgta tcttggagag ggctggtttt
    14761 tcttatgaag acaagaaaga tcaggtcaag attgctaccc ttcgtcgaaa tttagaagaa
    14821 cgggcaggat ggactcgtga agatctcaag gctttacgcc aacgccatcg tacagtagct
    14881 gacaagcaaa attctatggc caatatgatg ggcatgccgc agactcctag tggtggtctc
    14941 gaggattata cgcatgattt gacagagcaa gcgcgttctg gcaagttaga accagtcatc
    15001 ggtcgggaca aggaaatctc acgtatgatt caaatcttga gccggaagac taagaacaac
    15061 cctgtcttgg ttggggatgc tggtgtcggg aaaacagctc tggcccttgg tcttgcccag
    15121 cgtattgcta gtggtgacgt gcctgcggaa atggctaaga tgcgcgtgtt agaacttgat
    15181 ttgatgaatg tcgttgcagg gacacgcttc cgtggtgact ttgaagaacg catgaataat
    15241 atcatcaagg atattgaaga agatggccaa gtcatcctct ttatcgatga actccacacc
    15301 atcatgggtt ctggtagcgg gattgattcg actctggatg cggccaatat cttgaaacca
    15361 gccttggcgc gtggaacttt gagaacggtt ggtgccacta ctcaggaaga atatcaaaaa
    15421 catatcgaaa aagatgcggc actttctcgt cgtttcgcta aagtgacgat tgaagaacca
    15481 agtgtggcag atagtatgac tattttacaa ggtttgaagg cgacttatga gaaacatcac
    15541 cgtgtacaaa tcacagatga agcggttgaa acagcggtta agatggctca tcgttattta
    15601 accagtcgtc acttgccaga ctctgctatc gacctcttgg acgaagcagc agcaacagtg
    15661 caaaataagg caaagcatgt aaaagcagac gattcagatt tgagtccagc tgacaaggcc
    15721 ctgatggatg gcaagtggaa acaggcagcc cagctaatcg caaaagaaga ggaagtacct
    15781 gtctacaaag acttggtgac agagtctgat attttgacca ccttgagtcg cttgtcagga
    15841 atcccagttc aaaaactgac tcaaacggat gttaagaagt atttaaatct tgaagcagaa
    15901 ctccataaac gggtcatcgg tcaagatcaa gctgtttcaa gcattagtcg tgccattcgc
    15961 cgtaatcagt caggaattcg cagtcacaag cgtccgatcg gttcctttat gttcctagga
    16021 cccacaggtg tcggtaagac cgagttggcc aaggctttgg cagaagttct ctttgatgac
    16081 gaatcagccc ttatccgctt tgatatgagt gagtatatgg agaaatttgc agctagtcgt
    16141 ctcaacggag ctcctccagg ctatgtagga tatgaagaag gtggggagtt gacagagaag
    16201 gttcgcaata aaccctattc cgttctcctc tttgatgagg tagagaaggc ccacccagat
    16261 atctttaatg ttctcttgca ggttctggat gacggtgtct tgacagatag caagggacgc
    16321 aaggtcgatt tttcaaatac cattatcatt atgacatcga atctaggtgc gactgccctt
    16381 cgtgatgata agactgttgg ttttggggct aaggatattc gttttgacca ggaaaatata
    16441 gaaaaacgca tgtttgaaga actgaaaaaa gcttatagac cggaattcat caaccgtatt
    16501 gatgagaagg tggtcttcca tagcctatct agtgaccata tgcaggaagt ggtgaagatt
    16561 atggtcaagc ctttagtggc aagtttggct gaaaaaggca ttgacttgaa attacaagct
    16621 tcagctctga aattgttagc aaatcaagga tatgacccag agatgggagc tcgcccactt
    16681 cgcagaaccc tgcaaacaga agtggaggac aagttggcag aacttcttct caagggagat
    16741 ttagtggcag gcagcacact taagattggt gtcaaagcag gccagttaaa atttgatatt
    16801 gcataaaaga ataaaagtat cagcatctga ccataagtca cagtggagtg aaactcaatg
    16861 aaaatcaaag aacaaactag gaagctagcc gcaggttgct caaaacactg ttttgaggtt
    16921 gtagatagag ctgacgtggt ttgaagagat tttcgaagag tataagctgc aagatgaatg
    16981 attttcttgt attgacgttg ttgttgacaa aaagtagcgg ataaatgaaa tccattccat
    17041 tatcatagat gataggctgg taggaaattt tcaaatagca tacaggaaat agatgtatgg
    17101 agttctggta gtagaaaggg agagagatga acattttagt tgcagatgac gaggaaatga
    17161 ttagagaagg aattgcagca tttctgacag aagagggtta tcatgtcatt atggctaagg
    17221 atggacaaga ggtcttggaa aaatttcaag atctccctat ccatctcatg gtattggatt
    17281 taatgatgcc taggaagagt ggttttgaag tgttaaaaga aatcaatcaa aagcacgata
    17341 ttcctgtcat cgtcttgagt gctctgggag atgaaattac tcagtcacag gtatttgatc
    17401 tctatgctga tgatcatgtg acaaaacctt tttctttggt actgcttgtc aagcgtatta
    17461 aggcgcttat cagacgttac tacgtcatag aggatatttg gcgatatcag gatgtaacag
    17521 tggattttac ctcttacaaa gcacattata aaaatgaaga aattgatctc aaaccaaagg
    17581 aattactggt actaaagtgt ttgattcagc ataaaaatca agttttaagt agagagcaga
    17641 tattggaaga aatttcaaaa gatgtagctg atttaccttg tgatagggtc gttgatgtct
    17701 atattcgtac tcttcgcaaa aaattagctt tagattgtat cgtgactgtg aaaaatgttg
    17761 ggtataagat tagcttatga taaaaaatcc taaattatta accaagtctt ttttaagaag
    17821 ttttgcaatt ctaggtggtg ttggtctagt cattcatata gctatttatt tgacttttcc
    17881 tttttattat attcaactgg agggggaaaa gtttaatgag agcgcaagag tgtttacgga
    17941 gtatttaaag actaagacat ctgatgaaat tccaagctta ctccagtctt attcaaagtc
    18001 cttgaccata tctgctcacc ttaaaagaga tattgtagat aagcgactcc ctcttgtgca
    18061 tgacttggat attaaagatg gaaagctatc aaattatatc gtgatgttag atatgtctgt
    18121 tagtacagca gatggtaaac aggtaaccgt gcaatttgtt cacggggtgg atgtctacaa
    18181 agaagcaaag aatattttgc ttttgtatct tccatataca tttttggtta caattgcttt
    18241 ttcctttgtt ttttcttatt tttatactaa acgcttgctc aatcctcttt tttacatttc
    18301 agaagtgact agtaaaatgc aagatttgga tgacaatatt cgttttgatg aaagtaggaa
    18361 agatgaagtt ggtgaagttg gtgaagttgg aaaacagatt aatggtatgt atgagcactt
    18421 gttgaaggtt attcatgagt tggaaagtcg taatgagcaa attgtaaaat tgcaaaatca
    18481 aaaggtttcc tttgtccgcg gagcatcaca tgagttgaaa acccctttag ccagtcttag
    18541 aattatccta gagaatatgc agcataatat tggagattac aaagatcatc caaaatatat
    18601 tgcaaagagt ataaataata ttgaccagat gagccactta ttggaagaag tactggagtc
    18661 ttctaaattc caagagtgga cagagtgtcg tgagaccttg actgttaagc cagttttagt
    18721 agatatttta tcacgttatc aagaattagc tcattcaata ggtgttacaa ttgaaaatca
    18781 attgacagat gctaccaggg tcgtcatgag tcttagggca ttggataagg ttttgacaaa
    18841 cctgattagt aatgcaatta aatattcaga taaaaatggg cgcgtaatca tatccgagca
    18901 agatggctat ctctctatca aaaatacatg tgcgcctcta agtgaccaag aactagaaca
    18961 tttatttgat atattctatc attctcaaat cgtgacagat aaggatgaaa gttccggttt
    19021 gggtctttac attgtgagta atattttaga aagctatcaa atggactata gttttctccc
    19081 ttatgaacac ggtatggaat ttaagattag cttgtagaca gattagtttt ttattaaagt
    19141 tcacataggg ttaacataag tgtattattc tttatataga taaaaatata gataaaagaa
    19201 aggatactaa tatggtatta gcgattattt tagtaacatt ccttattcga ttgatttttt
    19261 taaagcgttc gatagagaat gagaaacgaa tccttagcaa tggcgggaaa gaatttggag
    19321 ttgagaatac aaaacgatta acgttggctc atattgtttt ttatctctct tgcctcgttg
    19381 aagcaatggt gcataagaca atgtttgatg gcatgggcat ggttggttta gtcttgctta
    19441 ttttttctat gctgatgttg atgttggtga ttcacttgtt gggagatatt tggacagtga
    19501 agcttatgct tgtcaataat cacaaatatg tagatcatat cttgtttagg acagtaaaac
    19561 atcctaatta ctttttaaat attcttcctg agttgattgg cttgaccttg ttgagtcatg
    19621 cttatgtgac ttttgtttta gtttttccag tttatgcagt tattttgtat cgacgaatag
    19681 ctgaagagga aaagctatta catgaagtta taatcccaaa tggaagcata aagagataaa
    19741 tacaaaattc gatttatata cagttcatat tgaagtgata tagtaaggtt aaagaaaaaa
    19801 tatagaagga aataaacatg tttgcatcaa aaagcgaaag aaaagtacat tattcaattc
    19861 gtaaatttag tattggagta gctagtgtag tagttgctag cttgttctta ggaggagtag
    19921 ttcatgcaga agaggttggt ggtaggaata cccccacggt tacatctagt gggcaagata
    19981 tatcgaagaa gtatgctgat gaagtcgagt cgcatctaaa aaaaatattg agtgagatcc
    20041 aaacacaatt agatagaaaa cgacatacca aaactgtagc gctaattaac gagttgcaaa
    20101 acattaagaa aacgtatttg tataatttaa atgttttaaa agagaagtct gagttgccgt
    20161 caaaaataaa agcaaagtta gaagtagctt ttgatcagtt taaaaaagat acattgaaac
    20221 caggagaaaa ggtagcagaa gctgagaaga aagttgcaga agctaagaaa aaagcc
//
LOCUS       DAVHBD010000044        19651 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000044 DAVHBD010000000
VERSION     DAVHBD010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.044"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..199
                     /locus_tag="VVK04_001698"
     CDS             <1..199
                     /locus_tag="VVK04_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU3990330.1"
                     /translation="SKLKPLIAEDKAYNHALSKERSKVENIFAKVKTFKMISTIYRNH
                     HKRFGLRMNLIAGIINHELGF"
     gene            complement(188..835)
                     /locus_tag="VVK04_001699"
     CDS             complement(188..835)
                     /locus_tag="VVK04_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU3990331.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(944..1462)
                     /locus_tag="VVK04_001700"
     CDS             complement(944..1462)
                     /locus_tag="VVK04_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU3990332.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1689..2558)
                     /gene="rsmI"
                     /locus_tag="VVK04_001701"
     CDS             complement(1689..2558)
                     /gene="rsmI"
                     /locus_tag="VVK04_001701"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU3990333.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQILKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2561..2878)
                     /gene="yabA"
                     /locus_tag="VVK04_001702"
     CDS             complement(2561..2878)
                     /gene="yabA"
                     /locus_tag="VVK04_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU3990334.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2918..3808)
                     /locus_tag="VVK04_001703"
     CDS             complement(2918..3808)
                     /locus_tag="VVK04_001703"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU3990335.1"
                     /translation="MKQDQLKAWQLAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTGKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3805..4443)
                     /locus_tag="VVK04_001704"
     CDS             complement(3805..4443)
                     /locus_tag="VVK04_001704"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU3990336.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTNAVLFDGMGLAK"
     gene            complement(4559..5356)
                     /gene="proC"
                     /locus_tag="VVK04_001705"
     CDS             complement(4559..5356)
                     /gene="proC"
                     /locus_tag="VVK04_001705"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU3990337.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(5360..6622)
                     /locus_tag="VVK04_001706"
     CDS             complement(5360..6622)
                     /locus_tag="VVK04_001706"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU3990338.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(6632..7762)
                     /locus_tag="VVK04_001707"
     CDS             complement(6632..7762)
                     /locus_tag="VVK04_001707"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU3990339.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7842..9725)
                     /gene="cbpE"
                     /locus_tag="VVK04_001708"
                     /gene_synonym="pce"
     CDS             complement(7842..9725)
                     /gene="cbpE"
                     /locus_tag="VVK04_001708"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU3990340.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELSVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(9728..10615)
                     /locus_tag="VVK04_001709"
     CDS             complement(9728..10615)
                     /locus_tag="VVK04_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU3990341.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10605..11066)
                     /locus_tag="VVK04_001710"
     CDS             complement(10605..11066)
                     /locus_tag="VVK04_001710"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU3990342.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(11063..11971)
                     /locus_tag="VVK04_001711"
     CDS             complement(11063..11971)
                     /locus_tag="VVK04_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU3990343.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11964..12161
                     /locus_tag="VVK04_001712"
     CDS             11964..12161
                     /locus_tag="VVK04_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3990344.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12213..12884)
                     /locus_tag="VVK04_001713"
     CDS             complement(12213..12884)
                     /locus_tag="VVK04_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3990345.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12938..13159)
                     /locus_tag="VVK04_001714"
     CDS             complement(12938..13159)
                     /locus_tag="VVK04_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU3990346.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13431..14240
                     /locus_tag="VVK04_001715"
     CDS             13431..14240
                     /locus_tag="VVK04_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU3990347.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIKKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14421..15296)
                     /gene="aguB"
                     /locus_tag="VVK04_001716"
     CDS             complement(14421..15296)
                     /gene="aguB"
                     /locus_tag="VVK04_001716"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU3990348.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15306..16391)
                     /gene="aguA"
                     /locus_tag="VVK04_001717"
     CDS             complement(15306..16391)
                     /gene="aguA"
                     /locus_tag="VVK04_001717"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU3990349.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRSF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALEKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16388..17515)
                     /gene="nspC"
                     /locus_tag="VVK04_001718"
     CDS             complement(16388..17515)
                     /gene="nspC"
                     /locus_tag="VVK04_001718"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU3990350.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17515..18774)
                     /locus_tag="VVK04_001719"
     CDS             complement(17515..18774)
                     /locus_tag="VVK04_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU3990351.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18771..19631)
                     /gene="speE"
                     /locus_tag="VVK04_001720"
     CDS             complement(18771..19631)
                     /gene="speE"
                     /locus_tag="VVK04_001720"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU3990352.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
BASE COUNT         5697 a         4534 c         3490 g         5930 t
ORIGIN      
        1 cagcaaactc aagccactaa tagctgaaga taaagcttat aaccatgcgc tatctaagga
       61 gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatga tttcaacaat
      121 ctatcgaaat catcataaac gcttcggatt acgaatgaat ttgattgctg gtattatcaa
      181 tcatgaacta ggattctagt tttgcaggaa gtctaatgta attctcaagc tgtgagttca
      241 ttatgatttg taaatccgat atatcttcag cagctaaaaa cacattttga aatgttccaa
      301 gtccgttttc accaaaacta tattctctct tactatactt actcttatta ttctctatat
      361 agttagagtc aaggttctta acctcttgaa gttcattttc tttacttctg aggttaaaat
      421 cttttacttc tgaagttaag ttttttgact tctgtaagtc attttctttt acctgaaata
      481 tactcataaa gtctttaaca taaatgatgt tcggcttacc aagtccaagc cttactcttt
      541 cgatcagtcc tattcctttt tttacatcaa gctcatctaa tgtttttatg gcagttggct
      601 ttgagatatt tcttcttttc ataatttctt cgacagtaaa atagataaat actctgcctt
      661 ccttgtctat ccagttattc ttaaatgaca ttcctgtctg tttaagaagt atggaataaa
      721 ggataattgc ttctgctgat aagccccgaa attcttctct atcaactaat atctccggta
      781 cttttaagaa gttaaatctt tccgcttctc tgttataaaa atattcaaag tccatgcaag
      841 atcacctccc ttcttaaaaa tttgcaaaga aaaagacgat agtttttctt ctatcgcctt
      901 tggtaaccat ttttatgaaa ttttttaaag ttaaaaatat aatttataat actatcttct
      961 tccattttct gattttagtt ctgaaagttc caaaaggtgc aaccgtattt acatgaataa
     1021 acttatacac ttcccaagtc gctgttttag tcgcttcatc agcccacttt ctcatatgcg
     1081 gttcaaataa ttcttcctca ctcaacgaat caatcattgc agagatagaa ttaatatttt
     1141 catttaattt tgctttcaac tcttgcagag ataaatgagc gtaggtatct gtgaaccact
     1201 gatataattc accaagttga ttccatttaa atttatccga tggtgttttt acttgaagcc
     1261 cctttctttc atcttcttcc catttaagaa ccaagttggt ccaaccaacc tgataagcaa
     1321 ggttttctgc tggagttctg tcaacttcat cagctctctt atcttttaaa ttttctggaa
     1381 tattatcaaa ttctaaaata tatttctcaa atgttttctc tatctcagct tttagttctt
     1441 ctttattttc gtatgttcgc aaaaaatcac cttctttctg atttatcaat cctttgattt
     1501 aaaatgacct tatttttcta tttatacctt ctaagaacgc tataactgct gctccaacca
     1561 tcggtattcc gtatgggctt aataaaaaac ttaataccaa agcttctata ccaagtgata
     1621 catctttata ttatcatcac taattaagtt aaacagaaac agacagaatt attacatcct
     1681 gtctcccttt attgtttttc ttcccagtcg tggtaggcag cgtagagctg acttttattc
     1741 cactggtaaa tcttagcgac ttccttgata gcttggtttt tcttcacacc ttgctggatg
     1801 cgggtttgaa tttctacgaa caagtcttcc tcgtcctttt cctccacacc ctgactggca
     1861 ccctcaacaa tgagaagaca ttcgcccttg agtggcgttt cagcaatgct ttctaataac
     1921 tcagagatag tacctcgttg gtattcttca tagattttgg tcaattccct gaccaagaca
     1981 acggagcggt caccgtagac ttctaacata ttttccaacg tgtctgctac acgatgaggt
     2041 gattcataaa aaatctgagt ttcaggatag tcttttttcg agtcgaaaaa ttgcttttgc
     2101 tggcctgatt ttctcggcaa aaagccgtaa aagatatgtg gctgcggcgc taaaccactg
     2161 gcaatcaagg cagaaattcc tgcagaggca cctggaactg tcacaactgc aatttcttcc
     2221 tcaatagctg ccttaaccaa atcatgacca gggtctgaaa tgctaggcaa accggcatca
     2281 gagacctgag caatactttg ccctgctttc aagaaaccaa tcaaatcagg aattttttcc
     2341 ttggcattgt gctcatgaaa actgatctgc ttggtggaaa tgtcaaaatg cttgagcaaa
     2401 agacctgtat tgcgcgtatc ctcagcagca atccagtcca cttctttcaa gatctggata
     2461 gcacgaaaag tcatatcatc tagattgcca atcggcgttg ccactagata cagcttgcca
     2521 tagggagact gccccttaaa acttttttga atttgcatgc ttactccctg tataacaact
     2581 catcacagaa catacattct tcgtcctgct ctcgacgttg tccataaaaa tcattacata
     2641 cgtgaaatcc atcacggtaa atacgacgga cactttcgcg aacatgcttg gccttgacgg
     2701 gagcgtctgc ttccacctca cccaagcgtt ctcgcaactt actattttcc aagcgaagag
     2761 ctgtattttc ttctaccaag ctcttgagat ttttcttgat ggcttccaca tcggctaagg
     2821 ttaccaataa ttgttgggaa aaatcatcca gcgcgtcaaa taattctttt ttgtccataa
     2881 aacagccctt tcctttcttt atcattcatt tttgagttta tatttctttc aagaccagat
     2941 attccatggc attttgaaag ctgacattag cttgccacat ttttctagct tctagtaaat
     3001 cttgtagaat cactcttact cttacctgca agaggtcctg cccgcagaga acttcaagaa
     3061 tccgtaaaac ctgatcctgt ttttccttat catctgccaa gttggctaat ttggcaacct
     3121 gtagataact ttcttttttc ttagctacta accaagtcag caggcgttca ctttcatcga
     3181 ccaaggtcca aaaacttgcc tgattagcca acttttctgc ttcagctcgc gattgactaa
     3241 acttagctaa aagagtcgct tttttcttaa caagtcccat ttgttctaag agtaagataa
     3301 gtttttcttc ttgcttttta aagtggaaga tctgagtccg acttcggatt gtcggtaaca
     3361 tcttttcctc atcgctagtc aagaagaaaa tataaacttc actctggggt tcttcgatga
     3421 ccttgagcag agaattggct gcgttgggat gcattttatc cgcttgctcg ataataaaga
     3481 cctgttgctg gctttcaatc cctgcttgag aaaactgtcc caccaattcc ctaatgcgtt
     3541 ctgtcttgat gacctgattg actggcttaa tcaaggtgac atcgggaaat tctccctgtt
     3601 caatcagctt gcaacttcgg catttctcac atggtaagac gccaacttta cccgtacaaa
     3661 agaggctctt agctaaaaat tgcgctattt ccaagcttcc aaagaaacct gaaaagagat
     3721 aggcgtgatt gagctggtct tgttctaaga tacggacaaa acggtcaaac tgagctagtt
     3781 gccaagcctt tagttgatct tgtttcattt ggccaagccc attccgtcaa acaagacagc
     3841 attggtagtt tccacaactt gctccaaagg gagactagca tcaatcttga caatgcgatt
     3901 tccctcttta tccagaagag aaaggtagcc ttgacgaact tttttatgca agtccaaccc
     3961 ttccaaatcc aaacgattaa cctcgcggtc actattagca gcaatacgag ccagcccttc
     4021 ttccacctcg atgtcaaaat agagtgtcaa atcgggtttg aggccatctg tcgcaaactg
     4081 attgagccag tcaatggctt caatatctaa gccacgacca aatccctgat aggcaacaga
     4141 actatcgata aaacgatcca tgatgaccaa cttgccagct tcaagggctg gaagaacttt
     4201 ttccaccaaa tgctgtctgc gactggcaat atagagaagt agctctgttt tagcatccat
     4261 ctgagtatga cttggatcca aaatcacttc ccgaatcttc tccccaatca agactccgcc
     4321 aggttcacgg gtcgtcagca cctctactcc tttttcctct aaaattggta gcagagcctc
     4381 taaaacactg gtcttgcctg ctccctctgg tccctcaaga gagactaaaa atccttttga
     4441 catgtctaac tcatttcttt tttactactt ctattctatc aaaaaaatag gagtttgtga
     4501 caatcttttt gtgtcttctc atttcagcca ccataaaaga ggcagtcaaa gctacctctt
     4561 atttacctag ttcttgtgtt cgtttatagg cttgatgaac tgcctccatg actatgcctc
     4621 gaaaagcatg cgcttctaag cttgctacgc cagcaatagt cgaaccgcct ggactacaaa
     4681 cttgatcttt caaaactcca ggatgttgct ggctttctag gaccaattgc ccagctccta
     4741 ccacagtttg ggctgccatt ttcaaggctg tttctcgtgg taatcccgtc tgaacacctg
     4801 catctgccaa agcctcaata aagagataga caaaggctgg tccacagcct gcaagacctg
     4861 tcgctgcatt gattaagctt tctcctaatt caaccaagag accagccttg gataaaagct
     4921 gacaaaagag ctcactgtcc tcagccctgc aattaggaga caaggcataa ctaatcactc
     4981 cttgcccgat agaagcaggg gtattaggca tcatacgaat aattcggtgt tgacttggga
     5041 taagacttgc tagtttttct aaggtcaatc cagctgccat cgaaatcaaa agaagacttt
     5101 ctcttttttc aaggatggtc tggtattgag aaagcagttc agaaaactga gcaggcttaa
     5161 ctcctagaaa aatcacatct gcttctgcaa acatttcttc attgctggaa gcctgaccac
     5221 caaagtctgc aatgaaagca tctaccttag cttgactacg attggcaagg agaatctcat
     5281 ctgacgtcct agtctgcaag acagattttg ccaagctagc acccatattc cccaaaccga
     5341 taaatccaat cttcatctct tactccctta tctgcccatc accagcaacc acatacttgt
     5401 agctggtcaa ctctttcaag cccattggac cacgcgcgtg caatttctga gtagaaatcc
     5461 ccatttcaca accaagacca aattgtcctc catctgtgaa acgagttgag gcattaacat
     5521 acaccgctgc agagtccact tgatctgtaa agtatgctgc agcttcagca ttttccgtca
     5581 caatagcatc cgaatgatgg gtgctgtggg attcaatgtg cgcaaccgct tcttctaaac
     5641 tgctcacaac cttaacagca aggacatagt ctaaaaactc ggtgtcaaag tcttgggtct
     5701 cagctgcttg acctgaaaca aactggcttg ctttgctatc caagcggaat tgaattggtt
     5761 ccagtccagc ttccttacgc tctgcaacca gcatttgatc caagcgagga aggatgcttg
     5821 ctgccttgtt ttcatgaacc agcagaacct ccatggcatt acaaacagaa ggacgactgg
     5881 ttttagcatt gttgatgata gacagcgcct tgtcttcgtc tgcatcctta tccacataga
     5941 catggacaat cccagtccct gtctcgataa caggtacaat cgcattctca accactgcat
     6001 tgatcaagcc agctcctcca cgaggaatga gaaggtctag atagcccttg gccttcatca
     6061 tagcataact actttcacgg ctagtatcct ccaccagttg aatcacattt ggatgaatag
     6121 tagtcgtctc caagcccttc ttcaaggctg tgacaatggc atgggttgtt tgataggcat
     6181 ccttaccact acgaagaaca accgcatttc cactcttaag agtcaaagca gccgcatcag
     6241 acgtcacatt tggacggctt tcatagataa taccgatgac acccatagct acacgttttt
     6301 ttgtgataac caaaccattt tcaagctgac ttgtttctaa aacttcaccg attggatctg
     6361 gtaaggcaac cacttcacga attcctcttg ccatcgcttc tatacgatct gcatccaaat
     6421 aaagacgatc caacatcaca tctgagattt tccccttagc cgctgccata tcgagggcat
     6481 tagccgctaa aatttcctca gtagcagcca ctaagtgatc agccatggct agcaaggctt
     6541 ggtttttcac ttcttcacta gctgtgttaa tcgatttttt aacagcctgt acctgttcaa
     6601 attgttcttg tctactcacc atagtttacc tctaaaattc tgtaaaaagt agttggattt
     6661 caggagtaat ggaaatccag tcgtcacggt aaatcaagac acccttggct ttttgagaac
     6721 gcaacatatc ctccaaagca gatgctccaa attgcacgcg tccttttcca agtgattttc
     6781 cactttcctt atcaaatact gtcacgatat caccgtaaga aaagactcct tctgcttcaa
     6841 cgataccaga taagagaaga ctctttccat gttgagagag agcttccgca gcccctttat
     6901 caacccaaat agaaccttga ctctgagcat agaaggcaag ccattgtttc tgggtacgaa
     6961 gccccttctc ttgagcaaca aagtaagaac catcctcggt ctcctctgcc gcctcaatca
     7021 tggaatctga tttcaaggat gagcagatat aaacaggaac tcctgattcc gtcgcgatag
     7081 ttgcagcctt gattttggtt aacatacccc cagttccgtt tgacgaacca gctccaccag
     7141 ccatatcaat aatctcacga ttgatggtct cgattctctc caagcgtttg gctcttggat
     7201 ctgaattagg atttccagta tagagaccgt ccacatctgt caagaaaact aaaaggtctg
     7261 cttggaccat cgccgctact tgagcactta gagtgtcatt gtccccaacc ttgagctcat
     7321 caataacgac actatcattc tcattgatga taggaattgc cccacggttg agcaaaaccg
     7381 acaaagcctg atgggcattt ttataacgac gcttatccac aaagtcatct tgggtcagca
     7441 agatttgtgc agaaacgatt tgacgcaaga gaagattggt cgtatattct tccaacaaaa
     7501 gtccctgccc taccgctgct gaagcctgtt tatcagcaat tttagtcgga cgctttttaa
     7561 atcctaaggc tccaaaacca gccgcaatgg cacctgaaga caccaaaatc aactcatgac
     7621 cagcctcgtg cagcatagcc aactgctggg taatatcctt taccttacta cgtgataaac
     7681 ttccatcctc atttgtcaga gaagaagtac ccaccttaaa gacaatccgt ttgtatttca
     7741 tagtctcact ccgattattc atatttatcc attataacat gaataacagg aaatagaaaa
     7801 gagttgatag gaaaaagaag gccctaaaac cttcttttct actactgttc tgattccgat
     7861 ttgtttacac tcgtttcaga gctttgtgaa gttgaggatg tcaaatcttg actagttgaa
     7921 aaatttgtaa cactttcatg ttgactcgtt tctttatttt caagatcctt tttcactact
     7981 tctttggatt cttttatttc tgaatgactt gtagttttaa ttgtagcaga tttctcgatc
     8041 gaaacatcca ctaaccaggc accacttgaa tccacagtat aaccttctgg tgtcttaccg
     8101 ttcacaagta attgaccatt ttctttcaag aagtaccatt tatccttgtc cttgatccaa
     8161 cccacagctc gtgaaccgtc tgtcttgtag aaataccaat catttgcctt tttatgccag
     8221 ccttgcttca tagctcctga atcttccaga taataatgtt gaccagcaac ttctatctca
     8281 cctgtcttca tgacaccagt agaatccata tagtaccagg tttctttatc ttttacccag
     8341 cccattttca tttcccctga tggagcaaag taataccatt gccccatata ttgaagccat
     8401 cctgtcttca tagaaccatc aacatccaaa taataccact gctctttatc ttgaacccaa
     8461 ccaatttcca tctgattttc tttgttaaaa taataccaga ttccatcaat tttcttccaa
     8521 tttttagcag aagcaccaga gtctgtcaaa tagaaccaat gattgttcca ttttttccat
     8581 tgattctgta acaagatacc cgtttggtta aagtaatacc attcaccttc gatttcattc
     8641 caaccgacag catactctcc tgtagaatca ggcgcttgat accaccagtt cccatatgca
     8701 ctcttatgcc aaccagcttg aaaacttgga atcggcttgt aggatgttga aatattgaca
     8761 aaaccgtctt ttcgaatatc aaaaactgtt gcatcatagt ctttgctggc tgcgttgatt
     8821 ctctcaattc ctcgttcttt gagccaatta acatactcac tatcaacacc atttttccaa
     8881 ggtagactat ccgaagtttg aacaatcaaa ctcggactca aatttttaat gaaatccttg
     8941 gtatttgatt tgttggtatc atggtgatga ttaaacttca tcaaatcaac ttttccaatg
     9001 agaggaccat acttgtcttc tgctccatga acattatcta aatcgccccc aaggtaaatt
     9061 ttcttgccat tgactttcac cacgctaatc aaggaattgg aattgtcatc ccaaattttc
     9121 tttaattcac ccgatgaatc agtttcattt tcataattat agagctgaat atccatgtcc
     9181 ccaaactgaa aatgagcatc cccttgtgtg atattttgaa taactgaaac acctttttct
     9241 gcagcagtct gtaaaacctt atcatagcca tacagattat cccatagacg ttcagaatta
     9301 gtaatacgac tatcactata tttcttaaga tagactcggt caactggata ggtagacagt
     9361 aattcatcaa catttccaat atgatcactg tgggtatggg tcaccaaaat aaaatcaagt
     9421 ttttggacac tcaattcctt caaacgacga aagacacggt ctgttagaac atgcttataa
     9481 gacgtttcaa ttccttctct ccatggataa cgagaatcac ttccatctgg gaaatcataa
     9541 tcttctcctg tatccaccat ggcaaaatgt ccattgcttt caagaataat cgcatcactg
     9601 ccaccttctt gaacattgat aaagtggatt ttatttcctg aactttcttg agcctgaaca
     9661 ttcccatacc atgacaaacc taaaaaagcg cctacaagtg ctaaactagt taatttcttt
     9721 ttcattctta ctttctcaat ctctccaagg tttccttaaa aatctctggg atatctgctt
     9781 taaattccaa ggtcttacct gttctcggat gagtaaaacc taaagtcttg gcatgaagaa
     9841 attgtccatg tcctttcaaa gtcttgcgag gaccatagac ctcatcacca gcgactggat
     9901 ggccgatata agccatgtgg acacggattt gatgagtgcg ccctgtctcc agttgcaact
     9961 ctactaagct ataatcgcca aagcgttcca agacgtgaaa acgcgtcact gcaggcttcc
    10021 ctttagcagt tacagcctgt ttcttacggt ctttttcact ccggccaatc ggcgcttcaa
    10081 ttacaccacg atcattaggc agatttccat gaacaatcgc ccaatatttg cggagagact
    10141 ttttatcttt gagttcttgg gcaagtacta gatgcgcatc atcgttttta gcaatcatga
    10201 gaagacctga cgtatcctta tcaatacggt gaacaatccc tggacgcaga accccattga
    10261 tacccgacaa gtccttaata tgatacatga gggcatttac tagggttcca ctggtatgac
    10321 cagcactcgg gtgcacaacc attccctgag gtttgttaac gacagccaca tcctcatctt
    10381 ggtagactat ttctagcgga agatcctcag ccacatactc taatacctct ggttctggca
    10441 catggtaagt gacgacatca ccctcttgga ctgtgtattt agctttcttg acttgaccat
    10501 tgaccaagac ctggcctgat ttaatttgtt cattcgcgag actacgtgat aattctgaca
    10561 aatctgacaa agccttatcc aaacgcagac caccagtttc aattttaatt tccatttatt
    10621 tcctctttta gcattgcaat caataaaata atcactccaa ccgtcagata gctatctgcc
    10681 acattgaaaa ttgcaaagtt gataaagtca aggtggaaca tatccacaac aaagccctga
    10741 ctgaccctgt caataaagtt tccaagacca cccgcgatta ttagagtcaa acccaagacc
    10801 atccagaatg agtcctccat gtgtttatgt aaataccaaa tggcacctat cacgacaacc
    10861 agagtaatga cagcgaataa cagctgctga tcttgtaaga tagaaaaggc tgcacctcga
    10921 ttttgcaggt aggtcaagct aacgaaattg ggaatccagg agcgcacttc acccagtgga
    10981 atctgctgga cgatatagga tttgaccaac tgatccagcc caattaaaag cagtacaatg
    11041 actgccacta ttgctctttt tttcatgatt tcctcttttg atcaaaatat tcttgcatga
    11101 cttctacgaa gagagtccca gcttgactaa gctccacttc ttcacgttta acatagacca
    11161 tgcggttatc taggttatcc ttgagacgaa taactgtaat gccattaaca ctgtcactat
    11221 ctaaaaatcc agaacctgtc gcataggcgt ccgtccgctc caaaatacca ttcaaggtgg
    11281 cacggtctgt cacattaaac atctgtgagc tagcgctggt atcgacaaag ttctctgaat
    11341 aataaaggta ctcgtctttc tcttgagtga aacgaaccgt tggtaaatcc gctaaatcct
    11401 ccatgactaa ttcctctttc tgggctaaag gatgaccctc acagagataa atatgggtat
    11461 ggaaaggaat caattcgatg acctccagac ctaacttttc aacccgttgc ataatcccct
    11521 ttttattttg attgttgagg tagataatcc caatctcact atgcccttgc gccacttcat
    11581 ctaatatttg aacagtagtt gattcaaaaa tacggaagtt cttatagtca ggatagcgct
    11641 ctgaaaaggc cgtaatagtt ggtggtaaga agtcatagtg ctggctagca acggaaaatt
    11701 catctttttc ttcttcagga ttggcatact gattttgaaa aatatcaaat cctttaacca
    11761 attcttgcgc tttttcataa aattccatcc cacgacgggt caagaaagtc cctgagctgg
    11821 tccgacggaa aatcttaaag cccaactctt tttccaaatc acgaacagaa atagacagac
    11881 tcggctgact aacatacatc ttttcagcag cttcacgaaa agtaccacta ttggcaatag
    11941 ccacaacata gcgtaattgt tgaatgttca tcttctaccc ccaacttctt tatcttttca
    12001 ttataccata ttttagaagt tttccaaaaa ggaaaaaaga acatcctatt cttcttaact
    12061 atcttcacta tctgcctttc tcacgccaat cttattttca aaatcaattc aaaaaaataa
    12121 gtggctacac accacttcag tatcggaaag aaaaacgttg actatttgtg aaaaaagaaa
    12181 atgccggaaa attccgacat ttttttagta agctaacttc ctgaaaatag gagtaaccaa
    12241 acatcccaga aggcagtgat attgatgaga atatgaacta gtattggata gtagagattt
    12301 ttagtcatgc gatacaatag agctaaaatc agacctccac tagcataaat gaaaaaagca
    12361 agaggagtta aagcaaaatt gatatgaata taaccgaaaa taatagcaga aagcaaaaca
    12421 tctccgtacc aaggtgagtt tttgaaaaag gttgtcataa gcacacctcg ataaatcaat
    12481 tcctcagcaa taggggcgat gaagcaaacg atgagcaaga aataagggaa ctcctgtctc
    12541 cccatcattt ctaccgtttc attcaaagaa atctgatttg aagacaggga tatgaaatac
    12601 gaaaagagga agtcagacat atatgaaatg atgtagccca gtaaaaggta gatgaagtac
    12661 ctcagctgcc acttgaaatg aaaaattttc tttcctgcaa aaaccagtag atagatgacc
    12721 gctaagaaaa gaactccgct ctccatcaaa agcagaatct gaaaaaattc acgacttgct
    12781 ggtagatagg gctttgcgag gtgattgaaa actctccaaa accaagttga tttgtaaaaa
    12841 attaaggaca atgctagtaa aatttgaata gcccgttttt tcatattaaa ttctctgctt
    12901 tctccactta tttcttcata ttactaataa attttactta aaatctcgca gcacttcctt
    12961 tgcaaagatg attgcctcct ccaatatatc ctaaatcata ggtgcctctg ggacaaaatc
    13021 catgaaccgg cagagttaat actggttcta tttcccaatc gtacctacca ttaggatttt
    13081 taccatatga atctgctcca ccttgtatca gctctaattc ttcatttgtt agatttatat
    13141 tttttgtcat taaaatcatg atatatttcc tccattattc ttcagattag ttgagtaatc
    13201 tgatactcat acctacttac aaaaaaacta ttatattaag ttggtttttt aatttgtcta
    13261 gttgcaacat tgacaaacat agtatagcat atctttgcga aatatcctct tcaaatcatg
    13321 aattgtcatc aaaacatctt aaactataaa atcaattagt ctcaagcttt ctatcaattt
    13381 cttctccaaa atatgctata ataatagcaa aagataaaga aggaagacct atgattaaac
    13441 tactagcctt ggatatggac ggcaccctcc tcaatgaagc caaggaaatc ccacaagctc
    13501 acattactgc tattcacaaa gccattaaaa aaggtgtcaa actggttctc tgtacgggtc
    13561 gccccctttt cggtgtcctc ccctactaca aaaaactggg actcgacctc cagaatgagt
    13621 atgtgattgt taacaacggt tgttcaactc accagactag cgactggggc ttggttgact
    13681 ggcaagaact gagtccagct gacatcgaat acctctatga ccttgctgaa aagagtgatg
    13741 ttcagttgac actttttgac gagtcacatt attttgttct cggtggaaag cccaatcaag
    13801 ttattgaaaa tgatgctaaa ctagtatttt cagacctgac tgaaatttct cttgaggaag
    13861 cgactagtgg aaagttccgg atgttccaag gtatgttttt aggaacaaaa gaacaaacag
    13921 acgattttga gcagcgtttt gctgaagagc tttgccaacg attcagtgga gttcgttcgc
    13981 agcctgtcat ttatgaagca atgccacttg gaacgacaaa ggctactgct ctttcacgac
    14041 tagctgagat tttgaagatt gattcctcag agattatggc catgggcgat gctaataacg
    14101 atatcgaaat gctccagttt gcagggcttg ggattgcaat gggaaatgcc agcgattatg
    14161 tcaaatctct tgcggatgcc gttacctcaa gcaacgaaga agacggcgtt gcgcgtgcta
    14221 ttgagaaata tattctataa aaaagaaaag caaatagaca gaagttactg ctatttgctt
    14281 ttttgctaat attttaaaat acggactaat caatagagaa gaatagcgaa tcataaaaat
    14341 cgatttacta gatgccatag tatcttatag ttgctaataa gaagttagtc tagcagaatg
    14401 aatctctcat ttctcccaca ctaatctgta atttgtctat acatttctgg tcttctatct
    14461 cgaaacaagc cccagtttag gcgttcactt gctcccttgt ctaggttata agtagctaac
    14521 agaacagctt cttcttgtct ttcagctcgt tctagaatag ctcctgtttc atccgtcata
    14581 aaggaggaac cgtagaagtc aagactggaa ctctgtccgc cattttcctc actaggagta
    14641 acctcctcta aaccataacg attggctgcg atgactggaa caatattcgc tgctgcgtgc
    14701 ccttgcatag tacgttgcca gtgaccacaa ctatctgtat ccaaaattgg ctctgaaccg
    14761 atagctgtag gataaaagag caattcagca ccattcaatg caagacagcg cgctgtttca
    14821 gggaaccatt gatcccaaca gataccgata ccaatcttag catagcgagt attccagacc
    14881 ttgaaaccag tgttaccagg cgtgaaatag aatttttctt gataataatg gtcatctggt
    14941 atatgggtct ttcgataaac gcccagcact tccccatctg catcaatgac ggcaatagag
    15001 ttatacaaga cattaccatc tttttcatag aaactgattg gtaaaacaac ttgtagttcc
    15061 ttagcaatca ccttaaaatg ctgaatggca gtattttccg ctacagattg ggcatactgg
    15121 tagtagtcat actgacgttc ctgacagaaa tagggatgtt caaacaactc gggcaagaga
    15181 ataatttggg ctccttgctc agcagcctga cgtactaaac gctctgcggt ttggatattt
    15241 gttgccacat ccttagcgca ttgcatctga atggttgcaa ctcttacatt tctcatcttt
    15301 ttctcctatt ctggaatttg ttgggtgata cagtggatat tgccaccacc taagagaata
    15361 tctctggctg gtattccgac aactttacgg tctgggaaac acttgctgag gatatctaag
    15421 gccacttggt cgtttacatc ctcaaactgt ggaaccaaga cagccttgtt ggcgatataa
    15481 aagtttacgt aggaagctgc tagtcgttca cctgcgtatc gcttttcttc tccttcttca
    15541 tagatgtagc ctggcaaatc ttcttctgtc acaacttgtc gaactgcagg gataggcaat
    15601 ttatgaatgg tgaagtgaca accttttgca tctgtttcct gttctaagag ttcgagatct
    15661 gcttttgaca tggcatactg gggatcattt tcgtcatctg tccaagctaa aacaacctca
    15721 gcaggaccaa caaaggcagc aacattatcg acgtgttcat tggtttcatc ctgataaata
    15781 ccataaggaa gccaaataac tttttcagca ccaagacttt ctaataatgt gttttcaatc
    15841 tcctctttag tcaggttagg attgcgacca ggactaagca agcaactttc agttacgaga
    15901 atagttcctt gaccatcgct atggattgcg cctccttcca gtacaaaagg tttagcatca
    15961 tagacaggct tttccaaggc ctcagcaaaa cgactggcta cttggtcatc ctcttcataa
    16021 tcttgataaa gaccatcata ggtgcctccc caagcattga aggcccaatc cacggctaat
    16081 ttcttacctt tatcattgac gagaatggtt gggccagtat cacgcgccca ggcatcattg
    16141 gtgggaatgt ctaaataaac aaccttgtct ccaagatagg attgggcttc agatagatag
    16201 gcctgctcca ccaaaagata gactctttcc ccttctgcta tggtctcgat gatctgagta
    16261 aatgatcttt tagcagcctt tccttgaaaa ggccatgatc ctggtcgagt cggccatatc
    16321 atgagggtac catgatgggg ttcgtactct gctggcatgt gatagcctaa tttttttgga
    16381 ctgtccatca tgataatctc cctttaaagt cttgatagcc aaaagctttg agtaagctac
    16441 agtctccctg ttcgtccatg agatagagac ttggcaatcc aataccatta aaggtattat
    16501 ttttgacaaa agaataaatg gccatgtctt gaaaataaag tctgtctccg atttggactg
    16561 gattttcaaa actataatca ccaatcacat ctcccgtcag acaggtatta gaagaaagtc
    16621 tgtaggtatg ggctttttcc tgtgcctcaa agccatttct caaaggtgga cgatagggca
    16681 tctcaagtac atcaggcata tggcaggtcg cagaggcgtc taaaaccaag atttccatac
    16741 cattttctac aatatctaat acctcagttg ctaaataacc cgcattaagc gcaatggctt
    16801 caccaggctc gatatagatt tcaagattgt aagtttttcg gatacgcttg atttctgaaa
    16861 tcagcaaatc cacatcgtaa ccttctcttg taatatgatg accaccaccc atattgagcc
    16921 attttacctc atgtaagtag ggaccaaact gttcttctac tgctttcaaa gttgtttgta
    16981 aatcatctgc tccctgctcg caaagggtat gaaaatgaag tccgtcaacc aaatctagca
    17041 aatcactcgg aatcttgtct atagtaactc caaagcgaga acctggtgca caagggtcat
    17101 agagcgcatg atctccttga gttgaacact gagggttgag gcgcaaacca acactgacac
    17161 cagcctctcg acaacgcgga ccgtgtttac gcaactgtct ctctgagtta aagacgatat
    17221 ggtccattat ctctagcaat tcctccaagt ctgcatcctt gaaagcaggc gcaaatacat
    17281 ggacttcacc aggaaattct tcccttgcca atttggcctc atagagtcca ctagctgtcg
    17341 tacctgatag atactggcta atcaagggat aagttttgta gagggaatat gccttctggg
    17401 caagcaagac cttgcaaccg gcctcttctt gtacatattg tagaatgcgg caattagctt
    17461 ctaacttggc caagtcaata acataggctg gtgttggtac ttgttctaac ttcattagtc
    17521 caccatttgt ggattttcaa ccacaaccca tggcaaacca tactcattca aagcttccat
    17581 gaatggatct ggatctaact cctcaaggtt atacactcca gcttgtttcc aagttccgtt
    17641 catgactaat tttgtcccaa tcatggctgg aacgcctgtc gtgtatgaaa ttgcttgtga
    17701 cccgacttct gcatagcact cttgatggtc gcaaacattg tagatgtaga tagtcttttc
    17761 aacgccatct ttgacacctg taaagataca tccaatattg gtttttccga ctgtacgtgg
    17821 cccaagactg gcaggatctg gaagcaaggc tttcaaaaat tgaattggaa caatttcttg
    17881 gccgttaaag ttaatggtat ccgtacgaag gagtccaaca ttttcaagac atttcatgtg
    17941 cgtcaagtaa gattgaccaa aagtcataaa gaaacgaatg cgtttgacac ctggaatgtt
    18001 cttggccaat gattcgattt cttcatggtg aaggagatac atatcttttt gtccaacttg
    18061 agggaaatca tactcacgct tgatagacat agcttcgact tcgacccatt tcccatcttc
    18121 ccagtaagaa cctggcgcag aaacctcacg gagattaatt tctggattaa agttggttgc
    18181 aaatggataa ccgtggtcac cgccattaca gtctaaaatg tcgatataat ggatttcatc
    18241 aaaatagtgt ttgagggcat aagctgaaaa gacactagtt acacctgggt caaaaccaga
    18301 accaagaaga gcagtcaagc ctgcttcttt gaatttctct tgataagccc actgccatga
    18361 gtagtcaaag taggctgtaa aaccaagttc cttacaacgt ttttcgtaga tagcacgcca
    18421 ctcagggtct tctgtgtctt ctgcttcgta gttggctgta tcgatatagt gaacacctgt
    18481 tgccaaacaa gcatccataa tggttaaatc ttgataaggc agagctacat tcaaaacagc
    18541 ttctggtttg tagctttcaa tcaaggtaat gacctcttca accttgtcag catcaagtgc
    18601 tgcagtttca attttagtac ttgttttgcc ttctagcttc gctttcaagt catcgcattt
    18661 tgacttggta cggctagcaa tcataatctc tgtaaatgtt tcgctatctt gacaaatctt
    18721 tgaaatagca acttgggcaa cgcccccaca accaataact agtaaacgac tcattttttt
    18781 ccttcctctt cttctaaaat gtcctcaaca tacttgggca acataaagga tcccacgtgt
    18841 aagtttgcag tgtagtattc tgtgaaaagc tggcgttttt tccaaccttc cttgtcaaaa
    18901 tctttgacag ggtggtattt tttcgatgca aatccaaata accaatagcc agctgggcta
    18961 gttggaatat gggcctgata aacccgacta attggaaagg cttgattgac ctttcggtgc
    19021 atgcttcggc aagccgactc atcctcatca aagaagggac tcccatgctg gtaaatcatg
    19081 atgccgtctt ccttcagagc tcgataacta ttgccgtaga attccttggt aaagagtcct
    19141 tccgtatggc caaatggatc tgtcgcatcg ttgatgataa tatcgtaatc atcttcgcag
    19201 tttcgcaaaa agcgtagccc attttggtag taaatggtaa cacgaggatc atctagccct
    19261 gcagcaaagt ctgggaaata ctcacgacag acctcgacca acatctcatc cggttccacg
    19321 atatcgattt gttccagttc aggatagagt gttagtactt gggcaacacc gccgtcacca
    19381 cccccaataa ccaatacttt ctttggattt gggtggacag ccatgggaac gtgaacggtc
    19441 atttcattgt agacgaaatc atccgcatct gagaacaaga catggccatt taaaatcagt
    19501 attttcccaa aagctggcgt atccaagact tcgatatcct gccattcact ttttccagcg
    19561 taaagttgct tggctgttct cagagacaat ttgacatctg gagtatgaac ttcagaaaac
    19621 cataaatcca tctatttctc cttatattat a
//
LOCUS       DAVHBD010000045        18602 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000045 DAVHBD010000000
VERSION     DAVHBD010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.045"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..661
                     /locus_tag="VVK04_001721"
     CDS             <1..661
                     /locus_tag="VVK04_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3990353.1"
                     /translation="FYLNKGKVYGFVGPNGAGKTTIIKMILGILKPDSGKITIFNQTV
                     EQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANMKGLSLDTERLNEYLSMVGLKDVK
                     KKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPINGLDPQGVIEIRSLIRFLQEKKGI
                     TFLISSHILSELDKVISDIIIINYGKVEFFGSCHYLLQKYNCRNLEEAYLACLAGGEY
                     D"
     gene            654..1391
                     /locus_tag="VVK04_001722"
     CDS             654..1391
                     /locus_tag="VVK04_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990354.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILAISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            1404..2114
                     /locus_tag="VVK04_001723"
     CDS             1404..2114
                     /locus_tag="VVK04_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990355.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHTLIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIMSFLLFLPIAIFMQICCI
                     RFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVCIWIMG
                     FEFSLLPKLIKLKEQNLV"
     gene            2663..2884
                     /locus_tag="VVK04_001724"
     CDS             2663..2884
                     /locus_tag="VVK04_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3990356.1"
                     /translation="MYRCLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            3330..3632
                     /locus_tag="VVK04_001725"
                     /pseudo
     CDS             3330..3632
                     /locus_tag="VVK04_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3788..5017
                     /locus_tag="VVK04_001726"
     CDS             3788..5017
                     /locus_tag="VVK04_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU3990357.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGLSVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            5037..7733
                     /gene="ppc"
                     /locus_tag="VVK04_001727"
     CDS             5037..7733
                     /gene="ppc"
                     /locus_tag="VVK04_001727"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU3990358.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSSGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    7816..8033
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8146..9150
                     /locus_tag="VVK04_001728"
     CDS             8146..9150
                     /locus_tag="VVK04_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU3990359.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVITSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            9219..10085
                     /locus_tag="VVK04_001729"
     CDS             9219..10085
                     /locus_tag="VVK04_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990360.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            10082..10840
                     /locus_tag="VVK04_001730"
     CDS             10082..10840
                     /locus_tag="VVK04_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990361.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRELFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLNQEEKAKMKISDYYQLFE"
     gene            10930..12690
                     /gene="dnaG"
                     /locus_tag="VVK04_001731"
     CDS             10930..12690
                     /gene="dnaG"
                     /locus_tag="VVK04_001731"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU3990362.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSRTSKYKNSRSTVIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENGENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            12693..13802
                     /gene="rpoD"
                     /locus_tag="VVK04_001732"
     CDS             12693..13802
                     /gene="rpoD"
                     /locus_tag="VVK04_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU3990363.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            13816..14145
                     /locus_tag="VVK04_001733"
     CDS             13816..14145
                     /locus_tag="VVK04_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU3990364.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            14179..15303
                     /gene="cpoA"
                     /locus_tag="VVK04_001734"
     CDS             14179..15303
                     /gene="cpoA"
                     /locus_tag="VVK04_001734"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU3990365.1"
                     /translation="MRKFPLFSSSLSFLLLILFKENDIIVVMEKKKLRINMLSSSEKV
                     AGQGVSGAYRELVRLLHRAAKDQLIVTENLPIEADVTHFHTIDFPYYLSTFQKKRSGR
                     KIGYVHFLPATLEGSLKIPFFLKGIVKRYVFSFYNRMEHLVVVNPMFIEDLVAAGIPR
                     EKVTYIPNFVNKEKWHPLPQEEVVRLRTDLGLSDNQFIVVGAGQVQKRKGIDDFIRLA
                     EELPQITFIWAGGFSFGGMTDGYEHYKKIMENPPKNLIFPGIVSPERMRELYALADLF
                     LLPSYNELFPMTILEAASCEAPIMLRDLDLYKVILEGNYRATAGREEMKEAILEYQAN
                     PAVLKDLKEKAKNISREYSEEHLLQIWLDFYEKQAALGRK"
     gene            15319..16644
                     /locus_tag="VVK04_001735"
     CDS             15319..16644
                     /locus_tag="VVK04_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU3990366.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            16675..16851
                     /locus_tag="VVK04_001736"
     CDS             16675..16851
                     /locus_tag="VVK04_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU3990367.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVRVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            16910..17044
                     /locus_tag="VVK04_001737"
     CDS             16910..17044
                     /locus_tag="VVK04_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU3990368.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            17108..18418
                     /gene="obgE"
                     /locus_tag="VVK04_001738"
     CDS             17108..18418
                     /gene="obgE"
                     /locus_tag="VVK04_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU3990369.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVTNKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEVYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            18428..18586
                     /locus_tag="VVK04_001739"
     CDS             18428..18586
                     /locus_tag="VVK04_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990370.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TTKENPSQ"
BASE COUNT         5797 a         3102 c         3978 g         5725 t
ORIGIN      
        1 attttattta aataagggaa aagtatatgg ttttgttgga ccaaatgggg ctggaaaaac
       61 tacaattatc aaaatgattc tagggatttt aaaaccagat tctgggaaaa taactatttt
      121 taatcaaacc gtagaacaga attccgaaaa tatattatct aggataggat tagttttggg
      181 accttcattt tatggtcatc ttgatgctta taaaaatttg aagttaatag caaatatgaa
      241 agggcttagt ttagatactg aaagacttaa tgaatatcta tcaatggtag gattaaaaga
      301 tgttaaaaag aaaaaagtga aaaatttttc aatgggcatg aaacaacgtc taagtatagc
      361 tgcatcattg ttaggtagtc cagaaatatt aatttgggat gaaccaatca atggacttga
      421 tccacagggt gtaattgaaa ttagaagttt aatccgtttt ctacaggaga aaaaaggtat
      481 tacattttta atatcaagtc atattcttag tgaactggat aaagtgatat ctgatattat
      541 aattataaat tatgggaaag ttgaattttt tggttcttgc cactaccttt tacaaaagta
      601 taattgtcga aatctggaag aagcctactt agcttgttta gctggaggtg aatatgatta
      661 aattagagtt tctaaagcag aaaaaaagca tcttatggtt tgttcttatt tttccaataa
      721 ttctgaatgc tttgttatat atagacttaa cttttaggta tcgaggttat ttattggtgc
      781 atcaaaatga acttgcttta tctaattggc agttaatttt taaagaacaa acaatatttt
      841 atttttctga actattttat ttagttctat ctttaataat ttacgaagtg tttgcagtag
      901 aatttaaaaa tgatgcatgg ttaaccgtaa tttcattgcc atttagaaac aagtacacaa
      961 taaattctaa attactcatt acagtggttt acacatttac tttttggttg tctgattata
     1021 ttagcttata cgttattggg aaggctattg ataacagttt agagattggt ttgattttct
     1081 ttttaaaaac atttaccatt caattaattt cctcgttgat gataatgtta ttatattttc
     1141 taactttagt acttataagg aaaatttctg gaataatacc aattggtatt ataatgatga
     1201 ttttagcaat tagcatatac tacaacgatt ataattttaa gatttactta ccatttactt
     1261 atctttctca tgcttttaga gtgactgaaa gtcaatttta tatgatttta ctatctaata
     1321 taataatcat cgtacttttt tatatattaa ttcgtaaatt gaacgaaaga agttttgaga
     1381 tgaaacttta ataggtaata aaaatgaagt tacttaaaaa tgaattgatt aagagtaaaa
     1441 tatttttatt tattattgtt gacatctgta ttcagattct agtcattcta gctataaaaa
     1501 catatatttt agatatttcg gcaccatact cagagcttga ttataataag tattggtatg
     1561 ttttacacac tttaatatat atgccaatga tttttcctat acaaattttg tatcaaaatc
     1621 taagagaggc attgattgaa gataataata atggttggaa tatcatggtg attaacacta
     1681 ataatctcgt gaaaatcatc tatataaaag taacgataaa tatcgtgaga tgttttattt
     1741 gttattttgt ttatacaatt ttttctttaa ttcaattagg tggtatggga actgatatgt
     1801 tattaaccaa tataatattt cccaatataa tgtcatttct tttattttta cctatagcta
     1861 tctttatgca aatttgctgt ataagatttg attccatttt agcaaaggcc ttacctaata
     1921 ttttgctgat acttattgtt ttaatcacgt ttcagagtga ttggaatata tttatacctg
     1981 caacttatta ttatacagaa attcagtcaa ctacaaactt aggtattaaa ttattagttt
     2041 gtatctggat tatgggattt gaattttccc ttcttccaaa actaataaaa ttgaaagaac
     2101 aaaatctagt ttaaatgttg ctcgaaaatt aaataattga atacgattaa caatgaaaca
     2161 atacaacgtg agtcatgact tcaaagtaat tgattttatg attctggttt cttacgctta
     2221 attaagcaag ttgtattcac tttatcaaat tgttattact ctaaaaagcg tctaacagct
     2281 acagctatag agtgtctgtt tgcttctctt tacttttatt ttaaataatt cattaacctt
     2341 ccgtaagtgc ccaataataa ggtgtgttga agaagtctga gataaaatag ttctcagtca
     2401 caaaaaaagc tatagattcc cattggtgaa cagctccctg tcaagtagac agtaaaataa
     2461 tataaaatct taagcgacct gattcctgaa ttccagtgga gtcaggttgt tttttaaccg
     2521 tctttcttaa tattgtctta cctataatag atatgcttat gagaagtgtt taataaatta
     2581 attttagttc aaaatgtcca atttggacac tttgaatgat ttcttagttt tatatattat
     2641 acttttctca ggagaaagct agatgtacag atgtttgaga gatttgaggg aagatcacga
     2701 tttgactcaa aaacaaatag ctaaaatact ttcgtttaca aactcagctt atgctaaaat
     2761 tgaacggggt gagcatacgt taacagcaga tgtattggta actctctcaa acttttacga
     2821 tgtcagtaca gactacctat tgggattgac agattttcct gataaaattc gctttagaaa
     2881 ataatcacct caatttcata gagtgtgaaa atgaggtgat tttttatttg ttctttgaaa
     2941 attaaatagt ccaaaatggt actttcctca tttgtggagc aaatttgaat ggctcgccat
     3001 gataagagcg attttaaaac catcaataaa atagagcgat actttatatg ccatgataca
     3061 aatgatatac aatgatactt ctgaccgttc agcctgccaa cgtaaaagag cagcaagtga
     3121 aattcttatg atgacttcat cagtcatgcc acgttgaatg tgtgagtttg ttagataaac
     3181 gcaattaatc ctcaaaaggt tccccgaacc ttttgagttc tacagacgca tcacgtggag
     3241 tgtgtaagct tgttgctaaa agcgtaaaaa ccttggaacg aaaggaataa tagacttcct
     3301 gcgaaacaaa aatataatac aataaaacta tgaatgatga agcaagtaaa caattaagcg
     3361 atagccgttt caagagcctt gcaggtgttc agcgcacgac ttttgaagag atgttagccg
     3421 tgctaaaaac aacttatcaa cgtaaacgcg caaaaggtgg acgaaaaacc aaattaagcc
     3481 tagacgatct cctcatggta actattcaat acatgcgaga atagcgcact tatgaacaaa
     3541 ttgcggctga ttttggcatt cacgaaagca acataattag tcggagtcaa tggattgaag
     3601 caactcttat tcaaaatggt tttacgattt caaattctgc cttaattctg taaaaacagt
     3661 aaaattcgaa ggattgtaag gtaagagttt ttttctttct gaaaaaatgg tataatagca
     3721 atcaaaacta gaaaataaaa cggaatttgg aacagatttg tctgtatcct agtagagtgg
     3781 tgatgctatg aagattagta agaggcactt attaaattat tccatcttga ttccctactt
     3841 gcttttatct attttgggct tgattgtggt ctattcgacc accagtgcta ttttaattga
     3901 agaaggcaag agcgctttgc agttggttcg aaaccaagga atcttttgga ttgttagttt
     3961 gatactgatt gccttaattt ataaattgag actagatttt ttgagaaatg agcgactaat
     4021 cattttagtt atattaatag aaatgctttt attgttcttg gctcgtttta ttggtctttc
     4081 cgtaaacggg gcatacggtt ggatttcggt tgcaggagta actattcagc cagctgagta
     4141 cttaaaaatc attattattt ggtatttagc tcaccgattc tccaaacagc aagaagaaat
     4201 agctacttat gattttcaag ttttgactca aaatcaatgg cttccccgtg cttttaatga
     4261 ttggcgattc gttctcctag ttctgattgg aagtttggga attttccctg atttaggaaa
     4321 tgcgactatt ttagtcttgg tttccttgat tatgtataca gttagtggaa tcgcttatcg
     4381 ctggttttca accattctgg cgctcgtatc tgccgcttct gtctttgtct tgaccactat
     4441 cagcctaatc ggtgttgaga ccttttcaaa aattccagta tttggctatg tagccaagcg
     4501 ctttagtgcc ttttttaatc cttttgccga tcgtgctgat gcgggtcatc agttagctaa
     4561 ttcttatttt gccatggtca atggcggttg gtttggtcta ggtcttggga actcgattga
     4621 aaaacgaggt tatttgccag aagctcatac agactttgtc ttttctatcg tgattgaaga
     4681 atttggcttt gttggtgcca gtcttatttt agctctcttg tttttcatga ttttgcggat
     4741 tatcttggtc ggtattcgag cggagaatcc tttcaatgcc atggttgcac tcggtgtcgg
     4801 agggatgatg ttggttcagg tatttgtcaa tatcggaggg atttcgggct tgattccatc
     4861 tacaggagta accttcccct tcttatccca gggtggaaat agtcttctag tcttatcagt
     4921 ggcagtagcc tttgtcttaa atattgatgc cagtgaaaaa cgcgctaagt tgtaccgaga
     4981 attggaaaat caaccaatga accttctgtt gaagtaggat aaagaaagga tagtttatgt
     5041 ctcttcaaaa attagaaaat tctagtaata aaagtgttgt gcaagaagaa gtcttgattc
     5101 taacagaatt actggaagat attactaaaa atatgcttgc cccagagacc tttgaaaaaa
     5161 taatacagtt gaaagaatta tcaacgcagg aagattatca aggtctaaac cgtctagtga
     5221 ctagcttatc aaatgatgaa atggtctata tttcacgcta tttctctatc ttgcctcttt
     5281 tgattaatat ttcagaggat gtggatttag cttatgaaat caatcatcaa aataatattg
     5341 atcaggacta tttaggtaaa ttatctacaa cgattaaatt ggtagcagaa aaggaaaatg
     5401 ccgttgagat cctagaacac ttgaatgttg ttccggtttt gacagcccat ccaacacaag
     5461 tgcaacgcaa aagtatgttg gatttaacaa atcatattca tagtcttttg cgtaaatacc
     5521 gtgatgttaa gttggggttg atcaataaag ataaatggta caatgatttg cgtcgttaca
     5581 tcgaaattat catgcagaca gacatgattc gtgagaaaaa attaaaagtg actaacgaaa
     5641 tcacgaatgc tatggaatat tataacagct cctttttgaa agctgtacct catttgacga
     5701 cggagtataa gcgcttagcg caagcgcatg gtctgaattt aaaacaggct aaaccaatca
     5761 ccatgggtat gtggataggt ggtgaccgtg atggaaatcc atttgttaca gcaaagacct
     5821 tgaagcagtc tgcactcact cagtgtgaag tcatcatgaa ctactatgat aaaaagattt
     5881 accaacttta tcgtgaattt tctctttcaa ctagcattgt caatgtcagc aagcaagtca
     5941 gagaaatggc tcgtcaatcc aaggataact cgatttaccg cgaaaaagag ctttaccgtc
     6001 gtgccttgtt tgatattcaa tcaaaaattc aggcaactaa aacctatctg attgaggatg
     6061 aagaagttgg gactcgttat gaaaccgcca atgatttcta caaggatttg attgccattc
     6121 gagattctct actagaaaat aagggcgagt ccttgatttc aggtgatttt gtggaattat
     6181 tgcaggcagt agagatattt ggtttttact tagcatcaat tgatatgcga caagactcta
     6241 gcgtctatga agcctgtgtg gcagaactct tgaaatcatc aggaattcat tctcgttata
     6301 gcgagttgag cgaagaagaa aagtgtgacc ttctcttgaa agaattagaa gaagatcccc
     6361 gaattctttc tgcgactcac gcagaaaaat cagaattatt agcaaaagaa ttagctattt
     6421 ttaagacggc tcgtgttttg aaagataagt tgggagatga tgtcatccgt cagaccatca
     6481 tttcacatgc aaccagcctt tctgatatgc tagaattagc tattctgtta aaagaagtag
     6541 gactggtgga tacggaaagg gcgcgtgttc agattgttcc cctttttgaa acaattgaag
     6601 acttggatca ttcagaggaa acaatgagaa aatatctttc tcttagcctt gccaaaaaat
     6661 ggattgactc acgaaataac taccaagaaa tcatgcttgg ctactctgac agtaataaag
     6721 atggcggtta cttgtcatca tgttggaccc tctacaaggc tcaacaacaa ttgactgcta
     6781 ttggagatga atttggcgtt aaggttacct tcttccatgg tcgtggtggt actgttggtc
     6841 gtggtggtgg gccaacctat gaagccatta catctcaacc gctcaagtct atcaaggatc
     6901 gtatccgctt gacggagcag ggtgaagtaa ttgggaataa atacggtaac aaagacgccg
     6961 cttactataa ccttgaaatg ctagtatcgg cagctattaa ccgtatgatt actcagaaga
     7021 agagcgatac caatacccca aatcgttatg aagccattat ggatcaagta gtggaccgta
     7081 gttacgatat ctaccgtgat ttggtctttg gtaatgagca tttctatgat tatttcttcg
     7141 agtcaagtcc aatcaaggct atttcaagtt ttaatattgg ttctcgtcca gccgctcgta
     7201 agactattac tgaaatcggt ggattgcgtg ccatcccttg ggtattctca tggtcacaga
     7261 gtcgtgttat gttccctgga tggtacgggg ttggttcaag cttcaaggaa tttatcaata
     7321 aaaatccaga gaatattgct atcttacgag atatgtacca aaattggcct ttcttccaat
     7381 cgcttctttc aaatgttgat atggttttgt caaaatcaaa tatgaatatt gcttttgaat
     7441 atgctaaact ttgtgaagac gagcaagtta aggccatcta tgagactatt ttaaatgaat
     7501 ggcaagttac taagaacgtt atcttggcta ttgaaggaca tgacgaactc ttagctgaca
     7561 atccatatct aaaagctagt ctggattacc gtatgcctta ctttaatatt ctcaactata
     7621 ttcagttgga gttgattaaa cgccaacgtc gtggagaatt gtccagtgat caagaacgat
     7681 tgattcatat caccatcaac ggaattgcga caggattgcg taattcaggt tgataatttt
     7741 caagagtgaa tgctaaaagt gaatatcaaa aaaattctaa tagactattg acaagtagtt
     7801 taaaaatgat ataatttaac cattcagaaa agtaatcata caaacttttt agagagtctg
     7861 tggtagctga aaacagataa gtggcgatga tgaaaattgg gctgaatgct atttagaatt
     7921 tgaaattata aaaattcggt aagcacacct tacagtgcat ctcgttattg cgagactgag
     7981 cgatagggaa attccctata attgaggtgg taccgcgcat cgacgtcctc acacaagttt
     8041 tttgtgtgag gatttttttg atggaggtta gtatggaaag aaaacgatgg cgtcgcttgt
     8101 ttagataagt gaaatatgtt aaaggaaata aaaaggagaa acagaatgaa aaataaacgt
     8161 ttaattggaa ttattgctgc attagcagtc ttagtagcag gaagcttgat ttattcttca
     8221 atgaataaat cagaagctca gaataataag gatgagaaga aaataactaa gattggtgtg
     8281 cttcaatttg tgagccatcc atcccttgat ttgatttata aagggatcca agatggactt
     8341 gcagaagaag gatataaaga tgatcaagtt aaaattgatt ttatgaactc agaaggtgac
     8401 caaagtaagg ttgcgacaat gagtaaacaa ttggttgcaa atgggaatga ccttgtggtt
     8461 ggtatcgcaa caccagcagc ccaagggttg gctagtgcaa caaaagatct accggttatc
     8521 atggccgcta ttacagaccc aattggtgct aacttggtta aagatttgaa aaaaccaggt
     8581 ggcaacgtta caggggtatc tgaccacaat ccagctcaac aacaagttga actcatcaag
     8641 gctctgacac cgaatgtgaa aacaatcgga gctctttact caagtagcga agacaattca
     8701 aaaacacagg ttgaagaatt taaggcttat gctgaaaaag caggtctgac agtggaaaca
     8761 tttgcagttc cttcaacaaa tgaaattgcc tcaactgtca ctgttataac tagcaaggta
     8821 gatgctattt gggttccaat tgataacacc attgcatcag gatttccaac ggttgtctct
     8881 agcaatcaaa gttctaagaa accaatttat cccagtgcga cagctatggt agaagtaggt
     8941 ggtttggcat cagttgtaat tgaccaacat gaccttggtg tggcaacagg taaaatgatt
     9001 gtgcaagtct tgaaaggtgc aaaaccagcc gataccccag tcaatgtctt ttcaactggt
     9061 aagtcagtca tcaataaaaa aatagcacaa gaactaggta ttactattcc tgagtctgtt
     9121 ctcaaagaag caggacaagt catcgaataa ataaggtagg gaggaggaga ctcttcccat
     9181 tttttaaaaa gatgaatata gaaaggatta aataaaatat gattgtttcc attatttctc
     9241 aaggatttgt ctgggctatt ctaggtctgg gaatctttat gacatttagg attttaaact
     9301 ttccagatat gacgacagaa ggttccttcc ctcttggggg agctgttgct gtcactttga
     9361 taaccaaagg cgtgaaccca tttttagcga cacttgttgc tgtaggagca ggttgtttgg
     9421 ctggaatggc agcaggcctt ctttatacaa aagggaagat cccaaccttg ctctcaggga
     9481 ttttggtgat gacttcttgt cactcaatca tgctcttgat tatgggacgt gcgaatttag
     9541 gcctgcttgg aaccaagcaa attcaggatg ttttgccttt tgattcggat ttgaatcaac
     9601 tcttgacagg tctcatcttt gtgagtattg ttattgctct catgctcttt ttcttggaca
     9661 ctaaactcgg acaagcctat attgctacag gggataatcc tgatatggct agaagtttcg
     9721 ggattcatac tggacgcatg gagctcatgg gcttggtctt atcaaatggt gtgattgccc
     9781 ttgcaggtgc cctcattgct cagcaagaag gttatgccga tgtgtctcga gggatcgggg
     9841 ttatcgttgt ggggcttgca agtttgatta ttggagaagt tattttcaag agtttgagct
     9901 tggcagagcg tttggttact atcgttgtag gttctatcgc ttatcaattt ttagtgtggg
     9961 cagttatcgc acttggcttt aatacaagtt accttcgttt atacagtgcc ttgattttag
    10021 cagtctgcct catgattcca acatttaagc aaacaatctt gaaaggagcc aagttaagca
    10081 aatgacagca attgtagaat taaaaaatgc aaccaaaatc gttaaaaatg gctttgatga
    10141 agaaaagatt attttaaatg atgtttcctt agaaattttt gaacaggact ttatcacgat
    10201 tttgggtgga aatggtgctg gtaaatcaac cctctttaac actattgcag gaaccatatc
    10261 actaaccagt ggaactatcc gtattttagg tgaggatgtt accaagtttt caccagagaa
    10321 gcgcgctaag tatctgtctc gagtcttcca agatccaaag atggggacag ctcctcgtat
    10381 gacagtggca gagaatctcc tgattgccaa gtttcgtggt gaaaagcgtg aactatttcc
    10441 gagacgtctg gctagctata aggataagtt tcaggcgacc attgaaaaag tgggaaacgg
    10501 tcttgagaaa cacttgaata caccgattga gttcttatca ggtggacaaa gacaggcttt
    10561 gagtctcttg atggcaacct tgaagcgacc tgaattactc ttgttagacg agcatactgc
    10621 tgccctggat ccaaagacta gtgttgcttt gatggaattg acagatgaat ttgttaagaa
    10681 agatcaattg acagccctta tgattaccca tcatatggaa gatgctctca aatatggcaa
    10741 tcgcttgatt gtcatgaaag aaggacgggt tattcaagat ttaaaccaag aagaaaaagc
    10801 aaaaatgaaa atctctgatt attatcaact ctttgaataa agtagggaaa atgagtgaaa
    10861 tggtttactt tttttctgaa ataaagtata ctatataaag taaactatga taacatggag
    10921 gtattgtgta tggttgacaa acaagtcatt gaagaaatca aaaacaatgc caacattgtg
    10981 gaagtcatag gagatgtgat ttctttacaa aaggcaggac ggaactatct agggctctgt
    11041 ccttttcatg gtgaaaaaac accttctttc aacgttgtag aggataagca gttttatcac
    11101 tgtttcggtt gtggtcgctc aggtgatgtt tttaagttca tcgaggagta ccaaggggtt
    11161 ccctttatag aggcagtcca aatcttaggt cagcgtgttg gaattgaggt tgaaaaaccg
    11221 ctttatagtg agcagaagcc agcctcacct caccaagctc tttatgatat gcacgaagat
    11281 gcagccaaat tttaccatgc gattctcatg acaacgacta tgggcgaaga ggccagaaat
    11341 tacctttatc agcgggggtt gacagatgaa gtgcttaaac atttttggat tggtttagca
    11401 cctccagaac gaaactatct ctatcaacgt ttgtctgatc agtatcgtga agaggattta
    11461 ctggattcag gcctgtttta tctctcggat gccaatcaat ttgtagacac ctttcacaat
    11521 cgcattatgt ttcccctgac aaatgaccaa ggaaaggtca ttgccttctc aggtcgtatc
    11581 tggcaaaaaa cggattcacg aacttctaag tataaaaaca gccgatcgac tgtaattttt
    11641 aacaaaagtt acgaattata tcatatggat agggcaaaaa gatcttctgg aaaagctagt
    11701 gagatttacc tgatggaagg attcatggat gttattgcag cctatcgggc tggaatcgaa
    11761 aatgctgtgg cgtcgatggg aacggccttg agtcgagagc atgttgagca tctgaaaagg
    11821 ttaaccaaga aattggttct tgtttacgat ggagataagg ctgggcaagc cgcgacattg
    11881 aaagcattgg atgaaattgg tgatatgcct gtgcaaatcg tcagcatgcc tgataacttg
    11941 gatcctgatg aatatctaca aaaaaatggt ccagaagact tggcctatct attaacgaaa
    12001 actcgtatta gtccgattga gttctacatt catcagtaca aacctgaaaa cggtgaaaat
    12061 ctgcaggctc agattgagtt tcttgaaaaa atagctccct tgattgttca agaaaagtcc
    12121 atcgctgctc aaaacagcta tattcatatt ttagctgaca gtctggcgtc ctttgattat
    12181 acccagattg agcagattgt taatgagagt cgtcaggtgc aaaggcagaa tcgcatggaa
    12241 agaatttcca gaccgacgcc aatcaccatg cctgtcacca agcagttatc ggctattatg
    12301 agggcagaag cccatctact ctatcggatg atggaatccc ctcttgtttt gaacgattac
    12361 cgtttgcgag aagactttgc atttgctaca cctgaatttc aggtcttata tgacttgctt
    12421 ggccagtatg gaaatcttcc tccagaagtt ttagcagagc agacagagga agttgaaaga
    12481 gcttggtacc aagttttagc tcaggatttg cctgctgaga tatcgccgca ggaacttagt
    12541 gaagtagaga tgactcgaaa caaggctctc ttgaatcagg acaatatgag aatcaaaaag
    12601 aaggtgcagg aagctagcca tgtaggagat acagatacag ccctagaaga attggaacgt
    12661 ttaatttccc aaaagagaag aatggagtaa taatggcaac aaaacaaaaa gaagtaacaa
    12721 catttgacgt acaggtagca gaatttatcc gtaatcataa gcaaaaaggg acagcaacag
    12781 atgatgaaat caatgcaagt ctggttattc cttttacctt ggacgctgat gggattgaag
    12841 atctcttgca acggattcag gatgcaggga tttctatcac agataacgaa ggaaatccaa
    12901 gtgcgcgtgt tcttagcaat gaagaagaac cagaactcag cgatgaggac ttgattgggt
    12961 caacttctgc taaggtcaat gaccctgtcc gtatgtactt gaaagaaata ggggtcgttc
    13021 ctctcttgac caatgaagag gagaaagagt tggcactggc tgttgaagct ggtgatatcg
    13081 aagccaaaca acgtcttgcg gaagccaatc ttcgtttggt tgtttccatt gccaaacgct
    13141 atgtcggtcg tggtatgcag ttccttgact tgattcaaga aggaaatatg ggcttgatga
    13201 aggcggttga caagtttgac tattctaaag ggttcaagtt ttcaacttat gcaacttggt
    13261 ggattcgtca ggctatcact cgtgctattg cggaccaagc tcgtaccatc cgtatcccag
    13321 ttcacatggt tgaaactatc aataaattgg ttcgtgaaca gcggaatctc cttcaagaat
    13381 tggggcaaga tccgacacca gaacagattg ctgaacgaat ggatatgaca cctgataagg
    13441 ttcgtgaaat cttgaagatt gcccaagaac cagtatctct tgaaactcct atcggtgaag
    13501 aggacgatag ccaccttgga gactttatcg aagatgaagt gattgaaaat ccagtggatt
    13561 atacgactcg tatcgtcttg cgtgagcaat tggatgaaat cttagatact cttacagacc
    13621 gtgaagaaaa tgttctgcgt ctacgttttg gactagatga tggaaaaatg cgcacacttg
    13681 aagatgtggg gaaagtcttt aacgtaactc gtgagcgtat ccgtcagatt gaagcaaagg
    13741 ctttgagaaa actacgccaa ccaagtcgta gcaaaccgct tcgtgatttt attgaagact
    13801 aagagtgagg aaaatatggc ttatacagaa gagcaaattg aaaacatcaa aacacggatt
    13861 ttaacagcct tggaagaagt catcgaccct gagttgggaa tcgatattgt caatcttggt
    13921 ttgatctatg agattcgttt tgacggtgac acagggcaaa cagagattga catgactttg
    13981 acaactatgg gttgtccctt agcagacctt ttgacagacc agatttatga tgctatgata
    14041 gaggttccag aagtaacgga tactgaggtt aaattagtct ggtatccagc ctggacagtt
    14101 gaaaaaatga gtcgctatgc ccgcattgcc ctaggcatta agtaaacata taaaagcatg
    14161 tgagagacta gaggaaaagt gaggaaattt cccctctttt cctctagtct ctcctttctt
    14221 ttgctgattt tattcaaaga aaatgatata atagtagtta tggagaaaaa gaaattacgc
    14281 atcaatatgt tgagttcaag tgagaaagta gcaggacagg gagtttcagg tgcttaccgt
    14341 gaattagttc gtcttcttca ccgtgctgcc aaggaccaat tgattgttac agaaaatctt
    14401 ccaatcgagg cagatgtgac tcactttcat acgattgatt ttccctatta tttatcaacc
    14461 ttccaaaaga aacgctcagg gagaaagatt ggctatgtgc atttcttgcc agctacactt
    14521 gagggaagtt tgaaaattcc atttttctta aagggaattg tgaaacgcta tgtattttct
    14581 ttttacaacc ggatggagca cttggttgtg gtcaatccta tgtttattga ggatttggta
    14641 gcagctggta ttccacgtga aaaagtgacc tatattccta actttgtcaa caaggaaaaa
    14701 tggcatcctc taccacaaga agaggtagtt agactgcgca cagatcttgg tcttagtgac
    14761 aatcagttta tcgtagtagg tgctgggcaa gttcagaaac gtaaagggat tgatgacttt
    14821 atccgtctgg ctgaggaatt gcctcagatt acctttatct gggctggtgg cttctctttt
    14881 ggtggtatga cagatggtta tgaacactat aagaaaatta tggaaaatcc ccctaaaaat
    14941 ttgatttttc caggcattgt atcgccagag cggatgcgcg aattgtatgc tctagcggat
    15001 cttttcttgt tgcctagtta caatgagctc tttcctatga ctattttaga agctgcgagt
    15061 tgtgaggctc ctattatgtt gcgtgattta gatctctata aggtgatttt ggagggaaat
    15121 tatcgggcga cagcgggtag agaagagatg aaagaggcta ttttggaata tcaagcaaat
    15181 cctgctgtct taaaagatct caaagaaaag gctaagaata tttccagaga gtattctgaa
    15241 gagcatctgt tacaaatctg gttggacttt tatgagaaac aagccgcttt agggagaaag
    15301 taaaaagtga ggtaatctat gcgaattggt ttatttacag atacctattt tcctcaggtt
    15361 tctggtgttg cgaccagtat tcgaaccttg aaaacagaac ttgaaaagca gggacatgct
    15421 gtttttatct ttacgacgac agataaggat gtcaatcgct acgaagattg gcaaattatc
    15481 cgcattccaa gtgttccttt ctttgctttt aaggatcgtc gctttgccta ccgaggtttt
    15541 agcaaggcac ttgaaattgc taaacagtat cagctagata ttatccatac tcagacagaa
    15601 ttttctcttg gcctgttggg gatttggatt gcgcgtgaat tgaaaattcc agtcatccat
    15661 acctatcaca cccagtatga agactatgtc cattatattg ctaaggggat gttgatccgg
    15721 ccgagtatgg tcaagtatct ggttagaggt ttcctgcatg atgtggatgg ggttatttgc
    15781 cctagtgaga ttgtccgtga cttgctatct gattataagg tcaaggttga aaaacgggtc
    15841 attcctactg ggattgaatt agccaagttt gagcgtccgg aaatcaagca ggaaaatttg
    15901 aaagaactgc gtagtaaact agggattcaa gatggtgaaa agacgttgct tagtctttcg
    15961 agaatctcct atgaaaaaaa tattcaagca gttttagtag cctttgctga tgttctgaaa
    16021 gaggaagaca aggttaaact ggtagtagct ggggatggcc cttatctgaa tgacctcaaa
    16081 gagcaagccc agaacctaga gattcaagac tcagtcatct ttacagggat gattgctcct
    16141 agtgagacgg ctctttacta taaagcggcg gatttcttca tttcggcatc gacaagcgaa
    16201 acgcaaggtt tgacctactt ggaaagctta gccagtggaa cacctgtcat tgctcacgga
    16261 aatccttatt tgaacaacct catcagtgat aaaatgtttg gagccttgta ctatggagaa
    16321 catgatttgg ctggtgctat tttggaagcc ctgattgcaa caccagacat gaatgagcat
    16381 accttatcag agaaattgta tgagatttca gctgagaact ttgggaaacg agtgcatgag
    16441 ttttatctgg atgccattat ttcaaataac ttccagaaag atttggctaa agatgatacg
    16501 gtcagtcagc gtatctttaa gacagttttg tatcttccgc aacaggtggt tgctgtacct
    16561 gtaaaaggat ctagacgcat gttgaaggct tcaaaaacac agttgatcag tatgagagac
    16621 tattggaaag accatgaaga atagaaagag gaacagctat gaaaaaaaca attaatgaga
    16681 agcggtcgtg ataaaaagat tgcgggtgtt tgtgctgggg tggcccatta tctggatatg
    16741 gatccgacta tcgttcgagt catttggggt gttcttactt gctgttacgg agctggaatt
    16801 gtagcttaca ttattttatg gattatcgca ccagtagcaa ctgactattg aaaactagct
    16861 caattcatgc taagataata gaaaatagaa tgtaacgaag gagagaaaaa tggcatttgg
    16921 agataatgga aatcgtaaaa aaactatgtt tgagaaaata accttgttta tcgtgattat
    16981 catgctagta gcaagtttat tgggaatttt tgcaactgca attggtgccc tcagtaatct
    17041 ataaaataga ttcaagaaaa tttagtgact gggatttccc agcccttttt taaagtgaga
    17101 agaaataatg agtatgtttt tagatacagc taagattaag gtcaaggctg gtaatggtgg
    17161 cgatggtatg gttgcctttc gtcgtgaaaa atatgtccct aatggaggcc cttggggtgg
    17221 tgatggtggt cgtggaggca atgtggtctt cgttgtagac gaaggactac gtaccttgat
    17281 ggatttccgc tacaatcgtc atttcaaggc tgattctggt gaaaaaggga tgaccaaagg
    17341 gatgcatggt cgtggtgctg aggaccttag agttcgagta ccacaaggta cgactgttcg
    17401 tgatgcggag actggcaagg ttttaacaga tttgattgaa catgggcaag aatttatcgt
    17461 tgcccacggt ggtcgtggtg gacgtggaaa tattcgtttc gcgacaccaa aaaatcctgc
    17521 accggaaatc tctgaaaatg gagaaccagg tcaggaacgt gagttacaat tggaactaaa
    17581 aatcttggca gatgtcggtt tagtaggatt cccatctgta gggaagtcaa cacttttaag
    17641 tgttattacc tcagctaagc ctaaaattgg tgcctaccac tttaccacta ttgtaccaaa
    17701 tttaggtatg gttcgcaccc aatcaggtga atcctttgca gtagccgact tgccaggttt
    17761 gattgaaggg gctagtcaag gtgttggttt gggaactcag ttcctccgtc acatcgagcg
    17821 tacacgtgtt atccttcaca tcattgatat gtcagctagc gaaggccgtg atccatatga
    17881 ggattaccta gctatcaata aagagctgga gtcttacaat cttcgcctca tggagcgtcc
    17941 acagattatt gtaactaata agatggacat gcctgagagt caggaaaatc ttgaagaatt
    18001 taagaaaaaa ttggctgaaa attatgatga atttgaagag ttaccagcta tcttcccaat
    18061 ttctggattg accaagcaag gtctggcaac acttttagat gctacagctg aattgttaga
    18121 caagacacca gaatttttgc tctacgacga gtccgatatg gaagaagaag tttactatgg
    18181 atttgacgaa gaagaaaaag cctttgaaat tagtcgtgat gacgatgcga catgggtact
    18241 ttctggtgaa aaactcatga aactctttaa tatgaccaac tttgatcgtg atgaatctgt
    18301 catgaaattt gcccgtcagc ttcgtggtat gggggttgat gaagcccttc gtgcgcgtgg
    18361 agctaaagat ggggatttgg tccgcattgg taaatttgag tttgaatttg tagactagga
    18421 gactggtatg ggagataaac cgatatcttt ccgagatgcg gatggtaatt ttgtttccgc
    18481 cgcagacgtt tggaatgaaa agaaattgga agaactattt aatcgtctca atccaaatcg
    18541 tgccttgaga ttggcacgaa ctacaaagga aaatccatct cagtaaagaa gctaaaaaat
    18601 cc
//
LOCUS       DAVHBD010000046        14261 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000046 DAVHBD010000000
VERSION     DAVHBD010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14261
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.046"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            1..138
                     /locus_tag="VVK04_001740"
                     /pseudo
     CDS             1..138
                     /locus_tag="VVK04_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(330..1676)
                     /locus_tag="VVK04_001741"
     CDS             complement(330..1676)
                     /locus_tag="VVK04_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU3990371.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISFVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            complement(2016..3218)
                     /gene="rpsA"
                     /locus_tag="VVK04_001742"
     CDS             complement(2016..3218)
                     /gene="rpsA"
                     /locus_tag="VVK04_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU3990372.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(3380..3451)
                     /locus_tag="VVK04_001743"
     tRNA            complement(3380..3451)
                     /locus_tag="VVK04_001743"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3417..3419),aa:Gln,seq:ttg)
     gene            complement(3461..3541)
                     /locus_tag="VVK04_001744"
     tRNA            complement(3461..3541)
                     /locus_tag="VVK04_001744"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3505..3507),aa:Tyr,seq:gta)
     gene            complement(3591..3821)
                     /locus_tag="VVK04_001745"
     CDS             complement(3591..3821)
                     /locus_tag="VVK04_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU3990373.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3989..4633)
                     /gene="pcp"
                     /locus_tag="VVK04_001746"
     CDS             complement(3989..4633)
                     /gene="pcp"
                     /locus_tag="VVK04_001746"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU3990374.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(4648..5571)
                     /locus_tag="VVK04_001747"
     CDS             complement(4648..5571)
                     /locus_tag="VVK04_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU3990375.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(5568..6257)
                     /locus_tag="VVK04_001748"
     CDS             complement(5568..6257)
                     /locus_tag="VVK04_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU3990376.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(6322..7026)
                     /locus_tag="VVK04_001749"
     CDS             complement(6322..7026)
                     /locus_tag="VVK04_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3990377.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(7082..8104)
                     /locus_tag="VVK04_001750"
     CDS             complement(7082..8104)
                     /locus_tag="VVK04_001750"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU3990378.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(8234..10705)
                     /gene="parC"
                     /locus_tag="VVK04_001751"
     CDS             complement(8234..10705)
                     /gene="parC"
                     /locus_tag="VVK04_001751"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU3990379.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(11125..13068)
                     /gene="parE"
                     /locus_tag="VVK04_001752"
     CDS             complement(11125..13068)
                     /gene="parE"
                     /locus_tag="VVK04_001752"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU3990380.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            13204..13845
                     /gene="plsY"
                     /locus_tag="VVK04_001753"
     CDS             13204..13845
                     /gene="plsY"
                     /locus_tag="VVK04_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU3990381.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(13890..>14261)
                     /locus_tag="VVK04_001754"
     CDS             complement(13890..>14261)
                     /locus_tag="VVK04_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU3990382.1"
                     /translation="CSPNLEQVQTMLEQAFKEKHYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSFKQLEQAIIDYIDYYNN
                     KRIKVKLKGLIPVQYRTKSFG"
BASE COUNT         4113 a         3176 c         2576 g         4396 t
ORIGIN      
        1 aataaagaga ttttaaacaa gcttttgagc tattcacaag acttgaaaca ccactatcag
       61 ctctatcaac tcttgctgtt tcacttccag aataaggaac cagagaaatt tttcggactt
      121 attgaggaca atcttaagcc caaatcattc atacctctct caactagatg taacttacaa
      181 aacccctgac ctcatgagcc actttcttcc tcctcatgag gtcagtttta ctttctgctg
      241 ttccagtatc gtttttcctc gctagatttc ctcaaaaggg cagactcctc ccttggtgcg
      301 tcacacgatt ttttcatctc gactgttctt taatgcatca ttaacgacgc ttttcttcta
      361 ggtggttcat aaggaacagg aagattcagg ttgacttttc taatcctaga ataaagtgct
      421 gaaaacaatt cggaataggc atagagacta gacaatttga ggagctgctt gcgtcctgtt
      481 cgaacacatt ttcctaccac gtgaagaaaa agatggcgga agcgtttgat tgttaaagtt
      541 tggaagtcac ctccagctag atgtttgaga aaaagataga gattgtaggc gatacagctc
      601 atcatcatac gaacttcgtt tttgattaag gttgaactat ccgttttatc gccaaaaaat
      661 ccctccttca tctccttgat gaaattctcg gcttgaccac gtccacgata aagctgaaac
      721 tggtcttggc ttgttccact cgtcatattt gtaacgaaag aaataacatc gtagaacaag
      781 tttccttctt ttcgttcaga gaactggcag acacgacgct tgtgcgacca agatcctgct
      841 tgatagagag tttctgagta ggcggagtgg ggcaagatgg ttaagtcctc atcctgtggg
      901 caagggaggg aaaggtctcc aagacggctc agaacagtat ttttcttgag ttttatgagg
      961 tagtattgcc ctgttttttc aattaaatcg tataattttg gggtcgcaaa gccactatcc
     1021 attcgaaaga gaagttgatt aaaccgttct aaaacaggtg tgataaagct gtctgcctct
     1081 tcagaacaat aacgattacc aggacgaagc tgggcattga aacaataacc tgtcttcccc
     1141 tcgaaagcat aaagaggatg atagccatga gcacgatagt gggcgttata agcaacacct
     1201 tcttgcttgc cataagttgt gaaatgggta gaatcgatat ctacaatgag ttggtttagc
     1261 tggtgaaact gtaaaaagaa ttcgaccaat tcaaggttga ggcatcgcaa actatggact
     1321 gtttcctcgt cagttctgga aagaaaacgg gataaggttg gctgtgaagc aagctgccct
     1381 ccttccaaca attttggaaa gtaggcatca gctgacaatt ctttacaagc atagtccgtt
     1441 ccatagcctg ttaacagttg aaagaggaac tggacaagga tatctgaatc cgaataacga
     1501 cagtagcggc gttggtcatt cgttactaaa tacttagaaa tccgctcttt tagtttcaac
     1561 tgggaaaaaa gttcctgaaa aaagataaga ccaccatact gggttaaatg acctccatcg
     1621 aaagatagtt ggtaaaaaga cttgttttgg aagtgatgat ttggtaaact gttcatgtga
     1681 gtttcctttc tttttgtgtt tttttctaca cttataccat aaaggggaaa ctcttttttg
     1741 tctagtaaaa aacacccatt gggtgaaaaa agaaaccatc caggatctaa gctaaggcaa
     1801 ggattctgga tggtttttag attaggggtg aataattggg gttaagcagg ttcatcctat
     1861 ttttcagact gtctttaaaa ccttcctcaa agataaagaa aggacgaaat ttgtcctttc
     1921 tcgagcttag ctttttttca acccactaca gttgacaaag agccagaaaa atcccttgtt
     1981 tagtaaacaa aggattttgt gaattttcaa tttgattaaa gttcgatatc accaaacaaa
     2041 tcagccattg aaaatcctgt ttgtgtttct ggaagttcga aatcacgctt ttcttgacgt
     2101 cttggacgac gtggacgagc agcacgtttt tcttcttttt gtccttcttc ttgggctgga
     2161 cgttcttcaa gagctttaat agaaagtgac acgcgttctg catctgcgtt aacttcaaga
     2221 actttaactt gaacttcttg accaacttta agagcttctt ttggattttc aatccgtttg
     2281 tgtgaaattt gtgatacgtg aacaagtcca tcgatacctg gcaatacttc aacaaatgca
     2341 ccgaagtcag tcaaacgttt aactgttcct tctactacat cacctttagc caatttttgc
     2401 tcaacgccat cccatggtcc tggtactgtt gctttaagtg aaagtgatac acgtccttct
     2461 tcttcgttaa gatcaaggat tttcacttca atttcttcac caacagttac aactgatttt
     2521 ggtgatacgt tacgttcatg tgacaattca gtcaagtgaa ccaatccgtc aacaccacca
     2581 aggtcgacga aagcgccgaa gcttgtgata cgagcaactt taccagttac aacatcacca
     2641 acagccaatt taccgaatac ttcagcgcga gctgctgcag tagctgcttc aacaacttca
     2701 cgacgtgaaa ggatgaagcg gttttcttta gcgttaactt ctttgatttt agtatcaaat
     2761 tcttgaccta caaaacgctc agcattacgt acgaaacgag tatccaacat tgaagctggg
     2821 ataaatccac gaacaccttc aaattctact gaaagtccac ctttaacggc acgcgttcct
     2881 ttaacagtaa caacttcttc ttcgcgacca acaagtttgt cccatgcttt gcgagcttca
     2941 aggcgttttt tagatacaag gtatgtaact gtatcagtat ctttaccaac tacttgacga
     3001 agtacaagaa catccaatac ttctcctact ttaacaaagt cattgatatc tgcatcacga
     3061 tcgtttgtca attcgcgaag agtcaagaca ccttcaacac cagttccaga gattgcaacg
     3121 ttagcttgag tcgcatcaac tgtcaatact tcagcactaa caacatcacc agtctcaact
     3181 tgactaacgc tatttagcaa atcttcaaat tcgttcatct aaaaaatcct ccaacaatca
     3241 agtttttctt aaacttgaca tacttataat ttttttccta agcacccgca aggacatgtt
     3301 catatcattc acgtctttca attataaaaa taaaataccc taagatattt tgctttttat
     3361 cttgattatt acctaagaac tggggtagct ggattcgaac caacgcatga gggagtcaaa
     3421 gtcccttgcc ttaccgcttg gctatacccc attaatgaaa tggagagaga gggattcgaa
     3481 cccccgaacc cgaaggagcg gatttacagt ccgccgcgtt tagcctcttc gctatctctc
     3541 ctacaatcaa catggactat tatatcatga aaatttcaaa aaaacaagac ttattttgct
     3601 aaattataat tttcaatcaa aatttccaca gctttttcca attttttata aaaactatcg
     3661 acattcccat tctttataat ggcaaattgt ccgtctaatt cggcaatttc tccgataact
     3721 tttttaccga tagtcaatgt ataaccttca aaactgtctt taccaacatt aactttggca
     3781 tccgctactt gaatttcgat ttttttatct ttcttgctca tttcatacct ctcttcactt
     3841 tttctatttt acaagaaaat tctaaaacta gcaagaaaaa actctatatc aggcttctct
     3901 gatatagagt tttatgtaaa caacctcaat tgatttagca tagttaatag ttagtaaaca
     3961 agcataattg actatccttt ttaggttatc agtgagtctc accgcctact aactgcaaat
     4021 ccttatcttt gtagtctaca atagcttcaa tagctacctc tatgcctctt acaatatcac
     4081 atagactcat tcctgcagta ttcggcttat ttactacttg ttccatcata tatggaatat
     4141 gcatgaaacc tgctctcata ttagggaatt ttttatccac taaataaaga gcttggtaca
     4201 tcaaatgatt gcaaacaaag gttcctgcac tattggatac aactgccgga agtccctgtt
     4261 ttttgatagc ttgtaccatc gctttgatag gtaaactact aaaataggcc gatgctccat
     4321 caatacgaat cggtgtatca attggttgat tgccttcgtt atcaggtatg cgagcatcat
     4381 cttgattaat agccactcgt tcaggtgtta agccggtcct gccgcctgct tgtccaatac
     4441 aaagtacagc atctggttga tatcgtaata tttctgcctc taaaacttct gacgacttat
     4501 aaaaaaccgt tggaatttct acccagcgaa cttcagcccc attaatctca gatggtaata
     4561 attttacagc ctccaaagct ggattaatct tttcacctcc aaaaggatta aaacctgtaa
     4621 ccaatatttt cattttattt tcctttacta aaatgcgaga aagtacatta agaatatgtg
     4681 aataacaatc attactagag caacacctgc ttgagccttt ataacgccat tctgatcttt
     4741 catatccatc aatgctgctg gtagagcgtt aaaattagca gccattgggg tcaataaggt
     4801 cccacaataa cctgctgtca tggcaagagc accagccaca attggattag ctcccagagc
     4861 aaatacaaag ggaactccaa cacctgctgt aataacggtg aatgctgcaa aagcatttcc
     4921 cataatcatt gtgaatagaa ccattccaag aacataggcc aaaactccta taaagcgact
     4981 atctgaagga acaataccgc taatcagatg agagataaca tcaccaacac ctgctacagt
     5041 aaaaatagcc cccaaagccc ctaataattg aggaacaata ccacttgttg aaacttgctg
     5101 agtcattcga ttattttctg ataacagact cttagggtga ctattggtaa tcacaagaac
     5161 agaaattgta gcaaacaagg cggcaaggct aatcgaaatc ttgctaaatt ctggaatcat
     5221 ttgcgctaag accaacgcaa gtattgccat cagcataact ggaataaaaa ttttattttt
     5281 caacctgtta gattcaatat tggctttcat ttcatctaag gatggcaagg ttccgatacg
     5341 gacttgctta aacaatgtta acagcgataa taggattaca ataataccaa tactcatatt
     5401 tggcatatag gaaccaccta taaacgtaat agacaataga gtccaaaatg cagatgtccc
     5461 aagtcgaact gggtttgttt tatctttata actacaatag gctgtatgga gaaattgaca
     5521 accaatcaca atataggtca actctaatag ttgctttgcc aactctgtca tttttgttct
     5581 cctcccctag tcttttttga tatcaatttt ttatcaaata aataattgta aatccccact
     5641 acaataagtg ttataacagc aacaataata gatgtagaag caatccctgc ataattgctt
     5701 tcatagccta actgatctaa tgttccccct atcaagagga ctcccccagc acctacaaac
     5761 gtattttgag caaagaaatt tccaaaattt tcattcgctg ccgcacgcgc ttttattgtc
     5821 tcatcttcaa cctctgttaa ctttctacct aattgagact ctgcagctgc ttctcccata
     5881 ggctgaacca aaggtctgac aaactgaggg tgtcctccta gacgaattga aaagaaacca
     5941 gctaactctc gaataaagaa ataaactgta tagaagtttc caactgtcag acctttaatc
     6001 tttcgaatca aatcgattga tcgttgcttg agtccaaagg tttctgacag ccccacaaga
     6061 ggcaaggtaa ccataaaaat cgtgagcact cgctgattgc taaattcttt tcccaaaatc
     6121 tccaaaaatt caacgagaga aacacctgaa actaaagctg taaccaaacc agctaagact
     6181 actgttgcaa ttgtatcaaa ttttaaaata aaacccacaa caatgattgc tattcctatt
     6241 aatctaatcc actccatatc aaactccttt atattcaaaa tgacagtatt ttaaaaattt
     6301 tatcaagatc aataccattc cttatttaat gtatttttct agttcttttt ggtatttgct
     6361 attggattcc aatttttctt tttgccattt tttaaaaacc tcgttatatt cttttgttgt
     6421 aacaatatct ttttgcaatt tcattccttt aaagatatat ggttccccct taataccaac
     6481 ttgtgagtat ggttttgaga atggtactac gttacttaca actggaaaac caccagatga
     6541 agctgttggc atcaataatg aactatctgt cgaccaagct tgagctttgg catatttttc
     6601 atatctcttc tctaggtcag tggtctcaga aacagcatct tctaacaatt tcttatattt
     6661 atccaaacca ggtttagcta caacatcctt atcttttcct ttcgtaatgc caaggtgttt
     6721 catggcagaa ccagattttg gatccataat attcaagtaa gacgctggat cttgatagct
     6781 tggagcccat cctgtactgt tcaaatcata gtctttttga gaaggagcaa cattgccgta
     6841 tttatcattt tccatcaaac catcaataac atttccaata acgtctgtcc tcgatgttcg
     6901 agtcgctata ctgtagccca atgatgctgg atctactgca tagacataag aaaatgttgt
     6961 cggtgcatct gcttctttat cagtttttcc acaagccact aaaatagctg acgtgctcag
     7021 gaccactcct gctgttaaga gccacttttt ctatttcata aaaaatctcc tttggtttat
     7081 tttaatctac ttttacaatc caaccttctg gcgcttcaat atcgccaaac tgaatacccg
     7141 tcaattcatt atataattta cgcgtcacag gacctacttc tgtttcacta tagaatacat
     7201 ggaaatcatc accatgttga atacctccaa ttggagaaat aaccgctgct gtaccacagg
     7261 cacctgcctc tacaaaacgg tcaagattat caattggaac atcaccctca ataggagtta
     7321 atcccaagcg atgttctgcc aaataaagca aggaatactt ggtaatagat ggcaagatag
     7381 atggactcaa tggtgttaca aattcattat cagctgtaat tccaaagaaa ttagctgatc
     7441 cgacttcttc aatctttgta tgagttgatg ggtccagata gataacatct gagaaatggc
     7501 gtgacttggc catttttcct ggtaagagac ttgcagcata gtttccacca accttagccg
     7561 cacctgtacc atttggtgct gcacggtcgt actcatcctg aatcaagaag ttggttggga
     7621 ccaaaccacc tttaaagtaa tttccaactg gcatagcaaa gatggtgaaa atgtactctt
     7681 ctgccggttt taccccgata atatctccga caccaatcaa aagagggcga agatataagg
     7741 ttccacctat tccgtatggt ggtacgtatt cttcattcgc acggacaact gctttacaag
     7801 cttctacaaa catgtctgtc ggaacttgtg gcatcaagag acggtcacat gtacgttgca
     7861 ggcgtttagc attttcatca ggacggaaca gttgaacact gccatcctta gtacgataag
     7921 ctttcaaacc ttcaaatgct tgttgtccat agtgaagact tggagaagac tctgaaatat
     7981 gcaaagttgc atcctctgta agctctcctt gatcccattg tccatttttg aaatgagcaa
     8041 gatagcgata aggtaatttc atataggaaa aaccgaggtt ttcccaatca atcgttactg
     8101 tcatattcca ctccttattc taaaaaccta tttcttatat tctacactat ttttctaaaa
     8161 tagcaagtat attttgtaat tttcagaaaa ttcctccaat aaaaaccatc ttagaactga
     8221 ttcttcattt cacttattta tcttcagtaa ctacttcctg aagataagcg tcaaaaactt
     8281 cttcatctga aatcgtgtca gaaatgaagc ttccattgct agtgcgttct gacaagttca
     8341 agtcttgcaa tcggctttca tagattgttc ctttattgga ttggacaagc agagtttggt
     8401 cgttcacatc cacttccgta ctgaagaaat cgccaacaaa tccttgctct gcaactgctc
     8461 ctgccaagaa gacacgatgc ggtttgtttt tcaactcacg caagacttgt aatcctcgtt
     8521 tggcacggct ggttgctaga atttcctcaa tggaaacacg tttcaagctt ccacgctggg
     8581 tcaagaggta gaaggacgaa gtattacaga taaagccaga ttggaggaca tcatcttctt
     8641 tcaaattcat agccttgaca cctgctgcct tagcaccgac aaccggaacc tcttcgatat
     8701 tgaaacgcag ggcataacca ttttgactaa ccaagacaac atcatctagt ttaatcggag
     8761 ccactgctac aatctgatct gtatcgtctt tgagcttagc atacttgaca gacttagatc
     8821 tataggtccg ccatggagtg aattcttttc gctctacccg tttgatttga ccaaggcgag
     8881 tcgctgcaaa gtaggttgtc gcatcgtcaa actgatccag tacttccaca taaaggattg
     8941 cttcattcgt ttcaaagttt gtgatggttt ggctcagatg ctctccgatg tccttccaac
     9001 gaatatctgc caactcatgg attggtctgt agatgacatt tccaagactt gtgaacatca
     9061 agaggtgctg ggttgtcttg gcagattgaa caaaaatcaa acggtcatca tcacgcttgc
     9121 caatttcttc caaggtggaa gccgcaaagg aacgtggact ggtacgcttg atgtaacctg
     9181 ccttggtcac gctgacgtag gtatcttcct cagcgataag actagctgta tcaatctcaa
     9241 ttgctttcgc agtgtcttct aaagaactca aacgaggagt tgcaaatttc ttcttgacct
     9301 cacgaagttc tttcttcatg agattgtaca tagtcctttc atcaccgata atagccgcca
     9361 gcatagcaat cttctcacga agctctgctt cttcttcctg caagacaacc acatcggtat
     9421 tggtcaaacg gtacagttgc aaagttacga tagcctcagc ctgttcttcc gtaaaatcat
     9481 agctaacttt gaggttttcc ttggcgtccg ccttattctc agaagcacgg ataagagcaa
     9541 tgacttcatc caaaatcgaa atcacacgaa tcaaaccttc gacgatacgg agacgtttct
     9601 cagccttttc tttgtcaaag cgtgaacgcg ccaaaatcac ttctcgacgg tgagcgatgt
     9661 agctagacag gattggaaca atcccaacct gacgaggtgt gaaattgtca atcgccacca
     9721 tattaaagtt gtagttgatt tgtaggtcgg tgtacttaaa taagtagttg agaacaagct
     9781 cagtattagc gtctttctta agttcgatag cgatacgaag accatcacgg tcagactcat
     9841 cacgaacctc agcaatccca gctaccttgt tattaacacg aacatcatcg attttcttga
     9901 ctagattggc cttattgatt tcataaggaa tctcagtaat aacgatttgt tccttaccac
     9961 cttttagctt ttcaatttca gtcttggaac gaacaaccac gcgccctttc ccagtctcat
    10021 aagctttctt gatttcatca cgaccctgaa taatagcccc tgtagggaag tctggtccag
    10081 gtaagaattc catgagttta tcaatctttg cagttgggtg gtcaatcatg taaactgcag
    10141 catctatgac ctcagctaaa ttatggggag gaatgtctgt ggcataacca gccgaaatcc
    10201 cagtcgaacc attgaccaag aggtttggaa aggctgctgg caagaccgtt ggttctttct
    10261 ccgtatcgtc aaagttccat gcaaaaggaa ctgtcttttt ctcgatatcc tgaagaaggt
    10321 agcctgcaat ttcagacaaa cgtgcctcag tataacgcat agccgcagga ggatctccgt
    10381 ccatagaacc gttattaccg tgcatttcaa ctagaatctc acgatttttc cagttctgtg
    10441 acatacgaac catggcatca tagatagaag aatccccgtg tgggtggaaa ttccccatga
    10501 tgttcccgac tgacttggcc gacttacggt agctcttgtc aaaagtattg ctatccttat
    10561 tcatagaata aagaatacgg cgctgaaccg gcttcaaccc atcacgaata tctggcaaag
    10621 cccggtcttg aataatgtac ttggagtagc gaccaaagcg ctctcccatg atgtcctcca
    10681 gggacatgtt ttgaatgtta gacataagat acaaagccca taaaatacca agtgaaaata
    10741 gaaaattctt gaagtaagca aactcacaag agaatttatc tttttcacac agtatctagg
    10801 gcgtgttcaa ctcctttcaa agaatgtaga gtaggttttt atgcagtaaa agatatttta
    10861 cgggaattcg tcccgtgttc agttacgata agtaaccaaa ctatcctgtt tgtatttttc
    10921 aatatgaaaa tctggttttc caaaattagt cttagtttgt gtcttaaccg ctcccttaag
    10981 cgcctcttta agataagcac tcatagcaga ttcttcatta ataatcctgc aattttttca
    11041 aaccaagatt ttcaaactgc tttttcacat agtcattcac atccgactct aatttccagt
    11101 ttactaacat attattttct ttcattaaaa cactgtcgct tcttctagcg taaacttgac
    11161 attatcttca atccatttac ggcgtggttc taccttatct cccatgagaa cattgacgcg
    11221 gcgttcggcg cgcgctaaat cttcaattgt gacacggatg agggtacgtg tttctgggtt
    11281 catggttgtt tcccagagct ggtccgcatt catctcacca agtcctttgt atcgttggag
    11341 ggtagcgcct ttaccgaact gtttacggag ttcttctagt tctccgtccg tccaagcgta
    11401 ggccacttct tctttcttgc ctttaccttt ggacatcttg taaagaggtg ggagggcaat
    11461 atagacatga cctgcctcga ctagcggacg catgtaacgg tagaaaaatg tcaagagcaa
    11521 ggtctggata tgggcaccgt cggtatccgc atcggtcatg ataatgatct tatcatagtt
    11581 ggcatcttca atagagaagt ctgctccaac acccgcacca atggtataaa tcatggtatt
    11641 gatctcttca tttttgagga tatccgccat cttggccttg gctgtattga caaccttacc
    11701 acgaagaggt agaatagcct ggaacttgcg gtcacgacct tgtttggcag aaccaccggc
    11761 agagtccccc tcaactagat agagttcatt cttagcagga ttcttagatt gggctggggt
    11821 caatttccca gacaacaagc ccttatcttt cttgtttttc ttcccatttc ggctctcatc
    11881 acgcgcctta cgtgctgctt cacgagcatc acgggccttg atagccttgc ggatgaggtt
    11941 agaagctaat tccccatttt ccataaggaa aaaggtcaac ttatcagcca ctattccatc
    12001 cacaactggg cgagctaggg ggcttcctag tttatccttg gtctgtcctt caaactgcaa
    12061 gtgttcttca ggaactaaga tagaaagaac ggccgctagt ccctcacgat agtctgaacc
    12121 ttcaaggttt ttatcttttt ccttgagaag acctgtttta cgtgcatagt cattcatgac
    12181 cttggtaatg gcagacttga gtcctgtctc gtgcgttcca ccgtccttgg tgcgaacgtt
    12241 attgacaaag gatagaatgt tatctgagaa tccgtcattg tactggaggg ctacttccac
    12301 ttgaaaacca ttgtcttccc cttcaaagta aagaactggc gtcaagattt ccttatcttc
    12361 gttgagataa gaaacaaaat cttgtactcc attctcatag tggaactcaa tcgcttcatc
    12421 tgttcgcttg tccgttaaag acaaggtcac atttttcaag agaaaggctg attcattaag
    12481 gcgctctgaa atggtattgt acttgaaatc tgtcgtagaa aagatagtcg cgtcaggcat
    12541 aaaagtaact ttggtgcctg ttttagactt gggtgctgta ccgattttct tcaaagtcgt
    12601 gacaggtttt ccaccatttt cgaaacgttg cttgtaaact gcgccatcac gggtaatttc
    12661 aacttctaac cagctagaaa gggcgttaac aacggaagaa cccactccgt gaagtccacc
    12721 tgatgtctta tagccacctt gaccgaattt ccctccggca tgaagaatgg taaagataac
    12781 ctcaacagtt ggaattccca tagcgtgcat acctgtcggc atcccacgtc catggtcttg
    12841 aaccgttaga ctaccgtctt tattgatagt tacatcgata cgatcaccaa acccagacaa
    12901 ggcttcatcg actgcattat caacgatttc ccaaactagg tgatgaagac cagcgccatc
    12961 ggtcgatcca atatacatcc ccggacgttt tcggaccgca tccaaccctt ctagcacctg
    13021 aatagcatca tcattataat tgttaatatt gatttccttt tttgacacaa ggaacctcct
    13081 attcgttcgt ctttactatt ctacaggttt tccaaggatt ttgcaaaatt tttctttctc
    13141 cgatgtgaca atttcagcag agattctctg cttttctttc ccaattcatg atataatagg
    13201 agtatgatta caatagtttt attaatccta gcctatctgc tgggttcgat tccatctggt
    13261 ctctggattg gacaagtatt ctttcaaatc aatctacgcg agcatggttc tggtaacact
    13321 ggaacgacca ataccttccg cattttaggt aagaaagctg gtatggcaac ctttgtgatt
    13381 gactttttca aaggaaccct agcaacgctg cttccgatta tttttcatct acaaggcgtt
    13441 tctcctctca tctttggact tttggctgtt atcggccata ccttccctat ctttgcagga
    13501 tttaaaggtg gtaaggctgt cgcaaccagt gctggagtaa ttttcggatt tgcgcctatc
    13561 ttctgtctct accttgcgat tatcttcttt ggagctctct atcttggcag tatgatttca
    13621 ctgtctagtg tcacagcatc gatcgcggct gttatcgggg ttctgctctt tccacttttt
    13681 ggttttatcc tgagtaacta tgactctctc ttcatcgcta ttatcttagc acttgctagt
    13741 ttgattatca ttcgtcataa ggacaatata gctcgtatca aaaataaaac tgaaaatttg
    13801 gtcccttggg gattgaacct aacccatcaa gatcctaaaa aataaaatgc cagttctgtg
    13861 aactgcaccc caaaagttag acaattaatt tatccgaagg atttagttct gtattgcaca
    13921 gggataagtc cttttagttt taccttaatt cgtttattgt tgtagtaatc aatatagtct
    13981 ataatagctt gttccaattg cttaaacgac tgaaacgact tctcataacc gtaaaacatt
    14041 tccgatttca gaatcccaaa gaaggactcc atcataccat tgtctgggct gttaccctta
    14101 cgtgacatgg atgcttgaat tcccttactc tctaggaacc gatgataaga atcgtgttga
    14161 tattgccagc cttggtcact atggagaatc gtattctcgt agtgcttctc tttgaatgcc
    14221 tgttccaaca ttgtttgtac ttgttctaaa ttaggcgaac a
//
LOCUS       DAVHBD010000047        12956 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000047 DAVHBD010000000
VERSION     DAVHBD010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.047"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..341)
                     /gene="rpsI"
                     /locus_tag="VVK04_001755"
     CDS             complement(<1..341)
                     /gene="rpsI"
                     /locus_tag="VVK04_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU3990383.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVER"
     gene            complement(360..806)
                     /gene="rplM"
                     /locus_tag="VVK04_001756"
     CDS             complement(360..806)
                     /gene="rplM"
                     /locus_tag="VVK04_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU3990384.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
     gene            1163..1480
                     /locus_tag="VVK04_001757"
     CDS             1163..1480
                     /locus_tag="VVK04_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU3990385.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(1631..2443)
                     /gene="folK"
                     /locus_tag="VVK04_001758"
     CDS             complement(1631..2443)
                     /gene="folK"
                     /locus_tag="VVK04_001758"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU3990386.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(2486..3040)
                     /gene="folE"
                     /locus_tag="VVK04_001759"
     CDS             complement(2486..3040)
                     /gene="folE"
                     /locus_tag="VVK04_001759"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU3990387.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3021..4343)
                     /locus_tag="VVK04_001760"
     CDS             complement(3021..4343)
                     /locus_tag="VVK04_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU3990388.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(4345..5319)
                     /gene="folP"
                     /locus_tag="VVK04_001761"
     CDS             complement(4345..5319)
                     /gene="folP"
                     /locus_tag="VVK04_001761"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU3990389.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5414..6121)
                     /locus_tag="VVK04_001762"
     CDS             complement(5414..6121)
                     /locus_tag="VVK04_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3990390.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6174..7592)
                     /locus_tag="VVK04_001763"
     CDS             complement(6174..7592)
                     /locus_tag="VVK04_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU3990391.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            7782..8594
                     /locus_tag="VVK04_001764"
     CDS             7782..8594
                     /locus_tag="VVK04_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU3990392.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            8933..9952
                     /gene="adhP"
                     /locus_tag="VVK04_001765"
     CDS             8933..9952
                     /gene="adhP"
                     /locus_tag="VVK04_001765"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU3990393.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            10186..11175
                     /gene="manX"
                     /locus_tag="VVK04_001766"
     CDS             10186..11175
                     /gene="manX"
                     /locus_tag="VVK04_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU3990394.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGTMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            11203..12006
                     /locus_tag="VVK04_001767"
     CDS             11203..12006
                     /locus_tag="VVK04_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU3990395.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            12030..12941
                     /locus_tag="VVK04_001768"
     CDS             12030..12941
                     /locus_tag="VVK04_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU3990396.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
BASE COUNT         3754 a         2889 c         2590 g         3723 t
ORIGIN      
        1 ttacgttcaa ctttacgtga gtcacgtgta agaagtcctg cgcgtttcaa tgaatcgcgg
       61 aagtctgggt ctacttgaag aagggcacga gcgataccgt gacggatagc tcctgattga
      121 ccagcgtatc caccacctac aacgttaacg aaaacgtcgt atgaacctac agttgaagta
      181 actgcgaatg gttggttgat gacaagacga aggtcagcgt gtgggatgta ctcttcaaca
      241 tcttttttgt taacagtgat tttaccagtt cctggaacaa ggcgaacgcg tgcaacagcg
      301 tttttacgac gtccagtacc tgcatattgt gcttgtgaca tactttattg ttcctttcct
      361 tagataagtt ctgaaatgtc aagaacttct ggttgttgtg cagcgtgagt gtgctcagct
      421 ccaacaaata ctttcaactt cataccttga gcgcgtccaa gtgtattgtg tggaagcata
      481 cctttaactg atttctcaat caaacgtact gcatttttag aacgaagttc acctgcagag
      541 atttgtttca atccacctgg gtggtttgag tgagtgtagt agattttatc agttgctttt
      601 ttaccagtca atttaacttt ttcagcattg ataacaatca cgaagtcacc tgtatcagtg
      661 tgtggtgtaa atgttggttt gttttttccg cgaagtacgc tagcaactac tgcagaaaga
      721 cgtccaagtg gtacatcagt tgcgtcaact acgtaccatt tacgttcaac ttggcctggt
      781 ttagccataa atgttgtttt gttcatgatt tctcctatat atagttcgat ttttgtttac
      841 ggtgatgggt gttccttccc atcgaaaagt atttggaagg ttccggggcc tttcaaatgg
      901 ggtaaacaat accgcctact atcataccaa attttacccc taaaagtcaa tagatatgaa
      961 aaatattttt cggtaacttc tcaaagtaac tgaaagttat ataatcaagt taatttggga
     1021 atttacctat taacttcggt agatttttgg gaattttttt ccttcttttt ccctgtagtt
     1081 aaaatccttt tcaaaaaatc accttttctt gatttttaat cctatttgct gtatgataag
     1141 ggaaaagaaa ggggacagag atatggcttt taccaatacc cacatgcggt ctgctagttt
     1201 tggcattgtt accagcttgc ccgatgacat cattgactct ttttggtata tcatcgatca
     1261 tttcttaaaa aatgtctttg aattggaaga agaactcgag tttcaattgc ttaataacca
     1321 aggaaagatt accttccact tttcaagtca acacctccct acagccattg attttgactt
     1381 taaccatcct ttcgaccctc gttatccccc aagagtactg gttttagaca tggacggtag
     1441 agaaactatc ctcctcccag aagaaaatga cctattttaa tactcaatga aaatcaaaga
     1501 gcaaactagg aagctaaccg caagctgtac ttgagtacgg taaggcgacg ctgacgtggt
     1561 ttgaatttga ttttcgaaga gtataaaaac tctagccttc agttgcaagt gactgaaaac
     1621 tagagttttt ctattttttc aaagcatcat acaagttgcg gatcggttgt tttaatatcg
     1681 gatggataaa atgaggcgca atttcctgta aggactcaag gacaaaaagg cgttccgcta
     1741 tgtaaggatg aggcaatatg aggtcgtctg tataaaggat ctggtcctcc acaaagagca
     1801 agtccaaatc aatcaaacga ggtccccaat gcacttctct cacccgtccc agctctgact
     1861 caatggctaa caaggtttct aacaagtctt gtgctggtag ccaggtttcc acctcaacca
     1921 cttgattggc aaagctatcc tgctccactc caccccaagg ctccgtcgct aagacactgg
     1981 actctttgag aatatggatg ccacgagctc gcagtttgtc aatggcttgc ttcaagtttg
     2041 cttgtttatc tcccatattg cttcctaggg cgataaaggc tcgttgcttg cggcgatgaa
     2101 tggttaccga gcaagtatct agtgacaaat gcaccggtgc ccaaggtttt ttcagttcca
     2161 acttcatttc ttggacaaga ggataagact caaaggtacg ttccaccagt ttataggcta
     2221 ccgtttcaat caaatcttca ctcgtttcct gaaaccaagt cgtccactgc tgacacaatt
     2281 ctccgtaatg gacagaggct gttaaatcca agtctgtagc tgccttggtc atatcatagg
     2341 ataggatggc tgaaacgaca aatttctgcc ccaattcttt ctcactagga aaaagaccat
     2401 gataggcaaa catttccaaa tccttaatct gcagttgatc cataatgatt cctttctaga
     2461 aaaatccgct tgaaacggat tctttttata gccccattaa acgataagct tggtcgcgga
     2521 ggtccttatc tgtttcaaat agaccacgag ctactgtcgt caaggttgca gtgcctggtt
     2581 ttctaacacc acgcatactc atacacatat gttccgcctc aatgacaaca aaggctcctt
     2641 tagcacctag atagtccatc aaggcatcgg ccacttcgat attcaaacgt tcttgaattt
     2701 gtggtttttt cgaataaact tcaaccgtac gggctagctt agacaagcct gccacacgac
     2761 catctggaat gtaggcaatg tgcgctctac cataaaatgg caagaagtgg tgttcacaca
     2821 tggtatggaa aaagatatcc ttttctacca ccatattatc gtcaataatt tcaaaggatt
     2881 ttgacaaatg ttcctctgct gtttgaccaa gacctgaaaa aatctcttga tacatacggg
     2941 ctacacgagc aggtgtttcc tgcaagccct cgcgattagc gttctctcct acagcctcga
     3001 taatcatttt tacagctgct tcaatctttt gtgtatccat tctcgttctt cctctccatc
     3061 agataggccc tcacttggct caagaaatac aaggaacctg tgacaatcct aactgtttgt
     3121 ttctcttctt ttttatctgt caaattctga tctagaaaat catgccaatc ttggtagctg
     3181 agatttctag acttagctgc ctctttcagc acgctttcat ccgtcgcccg actatccgca
     3241 aaatgtgtta gagtaagctc ggtatctggc atggctccca acaagtccaa catatcctcc
     3301 aaggccttgg ttttgataca agtgaagagg atttccttat gataatctgc aaaacgttct
     3361 tgcaaggtta ccaacaaggc cttgatagca tggggattgt gggctccatc caaaatcatc
     3421 aagggatctc ttgacacgat ttccaaacgc cccggccaac ttgtttcttc caaggcttga
     3481 ccaagaaagt cattgcttgc tagctctcga ccatcttctt gacaaaaagt atcaagtaaa
     3541 gctatggcca tcccagcatt ctctatttgg tacaaaccaa gcaggctagt ctggaagcga
     3601 ccttgtctga cagcgcttgt atagtcaaag acttcccctg tcaccacact ttcttgatga
     3661 cgaacctgat aatctgtccc gtaggcaagt ctcggcgcat ctttcccttc cgcaatgcgg
     3721 tcaatcacag ccaaggcttc tggagcaata cgccctgtta ccaagggcat cccttgtttg
     3781 ataatacctg ccttctgctc tgctatggcc tccaaggtgt caccaagtag ggccacatga
     3841 tccaagccaa tagttgtaat tcctgtcaaa atgggctgac agacattggt actatccaaa
     3901 agtccaccca tgccaacttc catgatggcc acatctactt gctctgaggc aaagtagtca
     3961 taggccaggg ctgtgataat ctcaaactcg gttgtgccct gtaaattggc gaccgcttct
     4021 ccctccagca aagactgata gtctgccatg agagcttcta gcctcgcttc tgagatcgat
     4081 tccccattga tgctaatctg gtctgtgtaa tgaatgagat agggcgagct aaacacgcca
     4141 actctcagcc ctagcttttc tagcatcttt ttcaaaaaag caatagtcga gcccttgccg
     4201 ttagtccctc cgatatggag gaccttgagt ttgagatggg gattgccacg caaagctaac
     4261 agttccacca ttcgttccaa gccaaaatgc ggttgatccg tccggtagtt agcaatccac
     4321 tgattgtttt caatttcttt catcttattt atattgtttt aaatctaaat tttccgcttc
     4381 atcagccaga cgaatggcag aggcaatttc aactgccatc ctgtgactag ctacgtcatg
     4441 cacgcgcacc acttctacac cctgtctcgc agcgatactg gttacatgag ccgaagccgt
     4501 gtcccgattt cggaaaccaa gctctgtctc aggattgact tcaaacccac tttcttcaag
     4561 gatattgatg acaaatcgct tgcgcgacac tccgagaaag attggatagc ccttctgatg
     4621 tagtttatcc aggtcccgta aaaggaggag attttctttc ttggtcagac caaagccaat
     4681 tcctggatcc aacaggatat tttctggtgc aataccagct tctgccgctc tcgctagtgc
     4741 tcgttcaaag aaagccacca tcaagtcttc gattggcaat gtttcaaagt cagctaactc
     4801 tttttctgta aaggtttgac caaaaccaaa atgagggaag ataagcgaac taggatgctg
     4861 aggtcgagcc ataactgggt taaacatgat gaccactttc gctctcgctt cagctaccac
     4921 atgagccatt ttctcatcac ccataagacc agtgatatca ttgactagat cggcaccagc
     4981 agccaaagca gcctctgcta cttgactctt ccaagtatca atagagatga ggacatcact
     5041 ttccttgcga atcgctttga tcactggaac aacacgctgg atttcctctt ctatctcaac
     5101 atagctactt cccggccgag tcgattctcc gccgatatct agcatactgg ctccttctgc
     5161 tatcaattta cgagcctgct ggagcgcctg ctcaagagca aaaaattgac caccgtccga
     5221 aaaggagtct ggggttacat tgataattcc gcaaataact gtctttgcat gattggcttt
     5281 acttgacata tcggtcactc cctcaaggat tttcatcata ttatttttct attttaccat
     5341 aaaaagaaaa agatggacac gattgcattc atctttccct agtagaaaga ggtcggttcc
     5401 tacataaaaa cttttaaaca gaaattccta atgtccgact cataatcacc acaagagcca
     5461 acaaacagaa agcaatccca ttaacaatca tgtgaagcaa gatcgacatt tccaaacgtt
     5521 gggtcttgta ggctgtccaa gatagaactg tcgacatacc tccataaatc aataaagaag
     5581 gtaaattact tggttgatgc aataaagcaa acacaatcgt accgactaca aatcccaagt
     5641 tctccttgcc tcggaaaatc tttttaggaa caatcccacg acacaagatt tcctcacaaa
     5701 tcggagcaag caaggctagc aagaagaaac tggaaatcaa cgaactattt tgaaccatat
     5761 cattaatctg agactggtta gctgttgtcg tctcatttga cagttgcaat aaaatggaac
     5821 caagtatatt tgacccgaca ataactagat aactcaagcc caaacgtgcc aaatctttag
     5881 ctctaaaaaa agaaaaatta aaactagcta acttggtttt acgagctccc ataataaata
     5941 gagccagaac cacaattgaa aggccagcaa ctatcagccc tgactgtagc agggctactt
     6001 cttttaaagt caaaatagag gtaaccacta ggggaacctg atataaaagg acggcaagta
     6061 aaaagaccaa aatccagcct gcacgattca acaattcttt ccacatattt ttctctttca
     6121 tcacctatct cctttgtatt aaaaaagggg ggaaatcccc ctgggtcatt ctattataag
     6181 gccatgctga tgtagttaag gataaacaag gcatccaaaa tccaaatcat gacatgaaca
     6241 tctttaactt gacctttaac aagcttagtc aaagtgtaag tcaagaaacc aactgcaatc
     6301 ccttgagtga tagagtagct gaatcccata aagatagatg tgaagaaggc aggaactgct
     6361 tcagacatat catcccaatg gatatttttc aagctaccaa gcatcataat cccaacgata
     6421 atcaagattg gagctgtagc cgctgttggt acgatcgcta gaagtgggct aaagaagctt
     6481 gaaatcgcaa aacagatagc tacaaccaag gctgtcaaac cagtacgtcc acctgcaccg
     6541 ataccagcag cagactcaac ataagtcgtt acgtttgaag tacctgcaat ggcaccgact
     6601 gtcgttccaa tcaaatcaga gtaaagagcc ttatccaatt tggctgattg gtgattttca
     6661 ccatttgtcg ctacgatacc aactttttca cctgtaccga tcaaggtacc aattgtgtca
     6721 aaaatatctg tcaatgagaa ggcaagaatg gccatcagag tttcaggcaa gcgagctgta
     6781 tctgaaacca aagctcccaa tccttctgaa ccaagagctg caccaaagat tgtcttcaaa
     6841 tcttcaaaag ctgcaccaac atggttatta gcaaaatcga tactagacaa atcaaccaaa
     6901 ccaactgcaa tagcaagaac agttgttgtc aagatagaga gaataattcc ccctttaatc
     6961 cctttgatga caaagaagat agtaatggca agtcctgcaa gagccactaa aacagctgga
     7021 ttattaaagc tgaccaatcc tggaactgct gaagagtttg ctgcaatcgt tgcttgagct
     7081 ttgtcagccc cttctcctac aacagtatag ttgcctggat caatcgtgaa tttcaaaagt
     7141 ccagcattct taatccctac ataggcaagg aagacaccga taccagctga aatagctgag
     7201 cgaagagcat tgggaatcga ttcaatgatc attttacgaa catttgtcaa ggtaataatc
     7261 aatgaaataa tcccacagat gaagaccata gctagggctt cttgccaaga ataaccaagc
     7321 ccgaatacaa ctgtaaaggt aaagaaggca ttgagtccca tacctggcgc ttgggcataa
     7381 ggtaagttag cataaaaagc catcatcaag gtacccgcta ctgcaccaat aatcgtcgct
     7441 aggaagacgc cctgagcagg cattcctgtt tgtgaaagta tttgtgggtt tacaaagaga
     7501 atatagctca ttgcaaagaa agttgttaaa ccagcgagaa cctctgtacg aacgtctgta
     7561 ccgttctctt ttagtttaaa taatttgtcc atcatcaatc tccttttaat ttttacgaac
     7621 aataatagaa ttatatcatt tatcattcac tttttcaatg tctttgtttg atttgtttaa
     7681 gaaattaatc caatttcatt ttttgtttgg aatctgcttt tctgcctgct ttctgttata
     7741 atagaagaca tcttatctga aaacacacta gaaaggtcca tatgacgaaa aaaattattg
     7801 cagttgacct ggatggaacc ctgctcaact cagacagtca aatttctgac tttaccaaaa
     7861 gaaccatcaa aaaagttgct gaaaaaggcc atcaggttat tattacgaca ggtcgccctt
     7921 accgtatgtc aaaagatttt taccgtgaac tgggcttaga cactcctatg attaacttca
     7981 acggatccct tactcattta ccagaccaag tttgggattt tgaaaagtgt ttgactgtag
     8041 acaaaaaata tctgctagat atggttcaac gttcagagga cattcaagcc gattttatcg
     8101 ctggagaata tcgtaaaaaa ttctacatta caaatcccaa tgaagaaatt gccaatccca
     8161 aactatttgg tgtagaagct ttccagcctg aagatcaatt ccagcctgaa ttggtgacca
     8221 aggaccctaa ctgtatcctc ttgcagacca gagccagtga caaatatgcc ttggcaaaag
     8281 acatgaacgc cttctaccag catcaacttt ctatcaatac ctggggaggt ccgctcaata
     8341 tccttgaatg taccccaaaa ggtgtcaaca aggcctttgc tttggactac ttgctcaaga
     8401 taatgaatcg tgacaaaaaa gatttgattg cctttggaga tgaacacaat gataccgaaa
     8461 tgctcgcttt tgctgggaag ggttatgcca tgaaaaatgc caatccagag ctactccctt
     8521 atgcagatga gcaaatttcc cttaccaacg accaagatgg ggttgccaaa accctacaag
     8581 acttattctt ataacctata ctgatactca atgagaatca aagagcaaac taggaagcta
     8641 gccgtaggtt gctcaaagca ctgctttgag gttgtagatg aagctgacgt ggtttgaaga
     8701 gattttcgaa gagtatgacc agcttgcaag ctggtctttg tgctcttttc acagtctcat
     8761 caaccagtta atcgattgtt ctactttttg tctccaaaac cttggaaaag gctttctttt
     8821 gtgatatact tcacatataa atacaagaga gctcgtcaca ctcgactctg ttgacaaaaa
     8881 atcaatccag tcccgttgtc cctgttctcg gtcaatatca aggaggatag ctatgaaagc
     8941 tgttgttgta aatccagaaa gcactggtgt tgctattgaa gaaaaagtac tccgtccact
     9001 tgaaactggg gaagcacttg tagaagttga atactgtggc gtttgccaca ccgacctcca
     9061 cgttgctcat ggtgactttg gtcaagtccc aggacgtgtt cttgggcacg aaggtatcgg
     9121 tatcgttaaa gagattgctc cagatgtgaa aagccttaaa gtcggtgacc gcgtcagcgt
     9181 tgcttggttc tttgaaggat gtggcacttg cgaatactgt acaactggtc gcgaaaccct
     9241 ttgccgtaca gtgaaaaatg ctggctactc agtagacggt ggtatggctg aacaatgtat
     9301 cgtaactgct gactatgctg tcaaggttcc tgacggactt gatccagccc aagcttcttc
     9361 tatcacatgt gctggagtaa caacctataa agctatcaaa gaagcaaaag ttgaaccagg
     9421 ccaatgggtt gttctttacg gtgctggtgg acttggtaac ctcgctgttc aatacgctaa
     9481 aaaagtattc aatgctcatg ttatcgcagt cgatatcaac aatgacaaac ttgcccttgc
     9541 aaaagaagta ggcgctgaca ttgtgattaa cggcctcgaa gttgaagatg tagctggact
     9601 catcaaagaa aaaactgatg gaggagctca ttcagctgtc gtaactgctg tgtctaaagt
     9661 tgccttcaac caggctgttg actccgttcg tgctggtggt cgcgtcgtcg ctgttggtct
     9721 tccttctgaa atgatggaac tcagcatcgt taaaacagtc ctcgatggaa tccaagtcat
     9781 cggttctctt gtcggaactc gtaaagactt agaagaagcc ttccaatttg gtgcagaagg
     9841 tctggtagcc ccagttgttc aaaaacgtcc agtagaagat gctgttgcca ttttcgacga
     9901 aatggaaaaa ggtcaaatcc aaggacgtat ggtactcgac ttcacccact aatctaatag
     9961 aaacctattt tcaaagttgg aagcttcttc caactttttt atattaaatt tttaaataag
    10021 aattcaagat tactcctcaa aaactcaaca tatcaacata caaaaataaa aattttttaa
    10081 ttttttatga taaatagttg ctttttttat gaaaacggtt tatacttaaa cagtcttaaa
    10141 gttttcttaa atgaaaacta aaacaaaaaa ggaggaatga caataatgag tatcggaatc
    10201 attattgcga gccacggcga atttgctgcg ggtattcatc agtcaggaac tatgatcttt
    10261 ggtgaacaag aaaaggttca agttgtgacc tttatgccaa atgaaggtcc tgatgatcta
    10321 tacgctaagt ttaataacgc tgttgctgca tttgacgcag aagatgaggt tctagttttg
    10381 gctgaccttt ggagtggttc tccatttaac caagctagtc gcgtgatggg agaaaatcct
    10441 gagcgtaagt ttgccatcat cacaggactt aacttaccga tgttgattca agcctacaca
    10501 gagcgcctca tggacgctgc tgcaggtgta gaaaaagtcg ctgctaatat cattaaagaa
    10561 gccaaagatg gcatcaaagc tcttccagaa gagctaaatc cagttgaaga agttgcaagc
    10621 gctgcagctg ctccagttgc ccaaactgct atcccagaag gaactgttat cggagacggt
    10681 aaattgaaaa tcaatcttgc ccgtcttgac acacgtctac ttcacggtca ggttgcaact
    10741 gcttggactc cagattcaaa agcaaatcgt atcatcgttg cttcagataa cgtggctaaa
    10801 gacgaccttc gtaaagaatt gattaaacaa gcagctccag gtaatgtcaa ggctaacgtg
    10861 gttccaattc aaaaactgat tgagatttca aaagacccac gttttggaga aacacatgcc
    10921 cttatcttgt ttgaaacacc tcaagatgcc cttcgtgcca tcgaaggcgg cgtgccaatc
    10981 aagactctta atgttggttc tatggctcac tcaacaggta aaacattggt caataccgtt
    11041 ttgtctatgg acaaagaaga cgttgctaca tttgaaaaaa tgcgtgactt gggtgttgaa
    11101 tttgatgtcc gtaaagtacc aaatgattct aaaaaagatt tgtttgactt gattaacaaa
    11161 gccaatgtca aataagccat tatttatgaa aggattttaa acatgtctat tatttctatg
    11221 gttttagtag tcgttgtagc cttctttgca ggtcttgaag gcatcctcga ccagttccaa
    11281 tttcaccaac cacttgtagc ctgtaccctt attgggcttg taacaggtca cttggaagca
    11341 gggattatcc tcggtggatc gcttcaaatg attgcccttg gttggtcaaa tatcggtgct
    11401 gctatcgctc ctgatgctgc acttgcttct gtcgctgctg ccattatcat ggttcttggt
    11461 ggtgacttta ccaagactgg tatcggtgtt gcccaagcgg ttgctatccc tcttgctgta
    11521 gctggacttt tcttgacaat gattgttcgt acaatttcag ttggtttggt tcatactgca
    11581 gatgctgccg ctaaaaaagg tgacttcggc gctgtggagc gtgcgcattt catcgcgcta
    11641 cttttccaag gacttcgtat cgcgcttcct gcagctcttc tccttatggt accaactgaa
    11701 actgtacaaa gtatccttag tgccatgcca gactggctca aagatggtat ggctatcggt
    11761 ggtggtatgg tcgttgccgt tggttacgcc atggttatca acatgatggc aactcgtgaa
    11821 gtatggccat tcttcgctct tggtttcgtt ctcgctgctg tgtcagatat tactctaatc
    11881 ggattcggtg ctatcggcgt tgctatcgct cttatctacc ttcacctttc taaaactggt
    11941 ggaaatggtg gcggaggagc cgcaacttct aacgacccaa tcggcgatat cctagaagac
    12001 tactaagata agaaaggact gaaaacatca tgactgaaaa acttcaatta actaaatcag
    12061 atcgtaaaaa agtttggtgg cgttcaacct tcttacaagg gtcttggaac tttgaacgga
    12121 tgcaaaactt gggctgggct tatacactca ttccagctat caaaaaactc tatactaaaa
    12181 aagaagatca aatcgctgct cttgagcgtc accttgagtt cttcaacact catccatacg
    12241 tagctgctcc agtcatgggg gttactcttg cgcttgaaga agaacgtgct aacggtgtgg
    12301 aaatcgatga cgctgctatc caaggggtta aaatcggtat gatgggacct cttgctggta
    12361 tcggtgaccc agtattctgg tttacagtac gcccaatcct tggatctctc ggtgcttcac
    12421 ttgcccttac tggcaatatc ttgggtccac tcctcttctt tgttgcatgg aacttgattc
    12481 gtatgtcatt cttgtggtat gttcaagaga ttggatataa ggctggatca gaaatcacta
    12541 aagatatgtc tggtggtatc cttcaagata tcactaaagg agcttctatc cttgggatgt
    12601 tcattcttgc tgtccttgtt caacgctggg taaatattaa atttgctttc gatgtttcta
    12661 aagttcaact agatgaaaag gcttatatcc attgggataa attgccagaa gggtctaaag
    12721 gtatccaaga agcattcgca caagtaggac aaggattgtc tcaaactcct gaaaaagtta
    12781 ctactttcca acaaaacttg gatatgttga ttcctggatt atcaggacta ctccttactt
    12841 tactttgcat gtacttactt aagaaaaaag tatctccaat cactattatc cttgccctct
    12901 tcgcagtggg tattgtggca catgttcttc acatcatgta atcaagcaac taaaaa
//
LOCUS       DAVHBD010000048        12857 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000048 DAVHBD010000000
VERSION     DAVHBD010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.048"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(112..1782)
                     /locus_tag="VVK04_001769"
     CDS             complement(112..1782)
                     /locus_tag="VVK04_001769"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU3990397.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            2012..2701
                     /gene="coaB"
                     /locus_tag="VVK04_001770"
     CDS             2012..2701
                     /gene="coaB"
                     /locus_tag="VVK04_001770"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU3990398.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2713..3264
                     /gene="coaC"
                     /locus_tag="VVK04_001771"
     CDS             2713..3264
                     /gene="coaC"
                     /locus_tag="VVK04_001771"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU3990399.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            3248..3811
                     /locus_tag="VVK04_001772"
     CDS             3248..3811
                     /locus_tag="VVK04_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU3990400.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            4093..4620
                     /locus_tag="VVK04_001773"
     CDS             4093..4620
                     /locus_tag="VVK04_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU3990401.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            4632..5147
                     /locus_tag="VVK04_001774"
     CDS             4632..5147
                     /locus_tag="VVK04_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU3990402.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALEQLGYLVKD"
     gene            complement(5144..5611)
                     /locus_tag="VVK04_001775"
     CDS             complement(5144..5611)
                     /locus_tag="VVK04_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU3990403.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRSPDTNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLRS
                     SEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYRHRTEDDWEKKIF"
     gene            complement(5664..6173)
                     /locus_tag="VVK04_001776"
     CDS             complement(5664..6173)
                     /locus_tag="VVK04_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3990404.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            complement(6139..6702)
                     /locus_tag="VVK04_001777"
     CDS             complement(6139..6702)
                     /locus_tag="VVK04_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3990405.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKMNDGYYQINGNS"
     gene            complement(6712..8700)
                     /gene="uvrB"
                     /locus_tag="VVK04_001778"
     CDS             complement(6712..8700)
                     /gene="uvrB"
                     /locus_tag="VVK04_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU3990406.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(8777..9730)
                     /locus_tag="VVK04_001779"
     CDS             complement(8777..9730)
                     /locus_tag="VVK04_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3990407.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            9903..12068
                     /locus_tag="VVK04_001780"
     CDS             9903..12068
                     /locus_tag="VVK04_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU3990408.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            12068..12808
                     /locus_tag="VVK04_001781"
     CDS             12068..12808
                     /locus_tag="VVK04_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU3990409.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
BASE COUNT         3866 a         2827 c         2344 g         3820 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaatc ttattgatga actgcttgca gtctgagaaa
       61 aaatgagctt ggatattatt tccaaactca cttaaagtca atttcaatcc actagaacaa
      121 gcctagtaca gttccatcgc tttcaacatc catgttgaga gctgctggac gttttggaag
      181 acctggcatg gtcataacat caccagttaa ggcaacgatg aagcctgcac ctaattttgg
      241 taccaattca cgaatggtaa tttcaaagtt ttctggtgct ccaagcgcat ttggattgtc
      301 tgagaaactg tattgagttt tagccataca gattggcaat ttgtcccaac cgttttgaac
      361 gatttgagca atttgtgttt gagctttctt ctcaaagttc actttgctac cacgatagat
      421 ttcagtgaca attttttcaa tcttttcttg gacagaaagg gcattatcgt acaaacgttt
      481 atagttagct ggattttcag caattgtctt aacaactgtt tcggcaagtg ctactccacc
      541 ttctgctcca tcagcccaga cactagccaa ttcaactggt acatcgattg aggcacagag
      601 ttcttttaag actgcaattt cagcttctgt atcagataca aattcgttaa tagctacaac
      661 tgctggaata ccgaacttac ggatattttc aacgtggcgt ttcaagttag caaaacctgc
      721 acgaactgcc tctacatttt cttcagtcag agcgtcttta gccacaccac cattcatctt
      781 aagggcacga agggttgcga caatgacaac tgcatctgga gatgttggca agtttggtgt
      841 cttgatatca aggaatttct cagcaccaag gtccgcacca aaaccagctt cagtaacagt
      901 gtaatcagcc aagtgaaggg ctgttgtcgt cgccaaaaca gagttacagc catgagcgat
      961 attggcaaat ggaccaccgt gtacaaaggc aggtgtaccg taaattgtct gaaccaagtt
     1021 tggcttaata gcatccttca aaatcaaagc caaggcaccc tcaacctgca aatcacctac
     1081 agaaacaggc gtacggtcat agcgataacc aataacgata ttcgccaaac gacgtttcaa
     1141 gtcctcgatg tccgttgcca agcaaagaat tgccatgatt tctgaagcaa ctgtaatatc
     1201 aaaaccatcc tcacgtggaa taccgtttag aggaccacca agaccaacag tcacatggcg
     1261 gagcgcacgg tcgttcaagt ccacaacgcg tttccagagg atacgacgtt gatcaatttc
     1321 cagctcattc ccttggtgca agtggttgtc aatcaaggca gaaagggcat tgttggcagt
     1381 tgtaatagca tgcatatctc cagtaaagtg gaggttgatg tcttccattg gcagaacttg
     1441 tgcataccca ccaccagcag caccaccctt gatccccatg actggaccaa gagacggttc
     1501 gcggatagca atcatggttt tcttgccaat cttgttcaag gcatccgcaa gaccaatggt
     1561 aagcgtcgac tttccttcac ctgcaggtgt tgggttgatg gcagtaacca agatcaattt
     1621 accgactgga ttgctctcaa ctgcacgaat tttatcaaag ctgagtttag ccttgtactt
     1681 tccgtacaac tccaaatcgt cataagaaat accaagtttc tctacaacat caacaattgg
     1741 cttcaactca atactctgtg cgatttcaat atctgttttc attcaaaatt cctctaacct
     1801 cttatatgat aattcattat atcacaaaac aagattttta acatcctaaa actctctaaa
     1861 cgttcgtaaa tatctctgtt tttaagactt ttagagtcct ttcttaaatt ttatatggct
     1921 ttatagtttg aaactatagt aaatcttcgt ttttaccaaa aatttatcac tttcatttta
     1981 cttaccgctt atttttgtgt acaatagtgc tatgaaaatt ttagttacat cgggcggtac
     2041 cagtgaagct atcgatagcg tccgctctat cactaaccat tctacaggtc acttggggaa
     2101 aattatcaca gagactttgc tttctgcagg gcatgaagtt tgtttaatta cgacaaaacg
     2161 agctctgaag ccagagcctc atcctaacct aagtattcga gaaattacca ataccaagga
     2221 ccttctaata gaaatgcaag aacgtgttca ggattatcag gtcttgatcc actcaatggc
     2281 tgtttctgac tacactcctg tttatatgac agggcttgag gaagttcagg ctagctccaa
     2341 tctaaaagaa tttttaagca agcagaatca tcaggccaag atttcttcaa ctgatgaggt
     2401 tcaggttttg ttccttaaaa agacacccaa aatcatatcc ctagtcaagg aatggaatcc
     2461 tactattcat ctgattggtt tcaaactgct ggttgatgtt accgaagatc atctggttga
     2521 cattgcacga aaaagtctta tcaagaatca agcagattta atcatcgcga atgacctgac
     2581 tcaaatttca gcaggtcagc accgagctat atttgttgag aaaaatcagc ttcaaacagt
     2641 ccagactaaa gaagaaattg cagaactcct ccttgaaaaa attcaagcct atcattctta
     2701 gaaaggaaaa ctatggcaaa cattctcttg gctgtaacgg gttcaatcgc ctcttataag
     2761 tcggcagatt tagtcagttc tctaaaaaaa caaggccatc aagtcactgt cttaatgact
     2821 caggctgcta cagagtttat ccaacctttg acactacagg tactctcaca gaatcctgtc
     2881 cacttggatg tcatgaaaga accctatcct gatcaggtca atcatatcga acttggaaaa
     2941 aaagcagatt tatttatcgt ggtacctgca actgctaaca ctattgcaaa actagctcac
     3001 ggatttgcgg acaacatggt aaccagtaca gctctagccc taccaagtca tattcccaaa
     3061 ctaatagctc ctgctatgaa tacaaaaatg tatgaccatc cagtaactca gaataatctg
     3121 aaaacattag aaacctacgg ctatcagctg attgctccta aggaatccct actagcttgt
     3181 ggagaccacg gacgaggagc tttagctgac ctcacaatta ttttagaaag aataaaggaa
     3241 actatcgatg aaaaaacgct ctaatattgc acccattgct atcttttttg ctaccatgct
     3301 cgtgatacac tttctgagct cacttatctt taaccttttt ccatttccaa tcaaaccgac
     3361 cattgttcat attcctgtca ttattgccag cattatttat ggtccacgag ttggggttac
     3421 acttggattt ttgatgggat tacttagctt gacggttaac acgattacga ttctaccgac
     3481 aagctacctc ttctctccct tcgtaccaaa cggaaacatc tactcagcta tcattgccat
     3541 tgtcccacgt attttgattg gtttaactcc ttacttagtc tataaactga tgaaaaacaa
     3601 gactggtctg attttagctg gggctcttgg ttccttgaca aatactatct ttgtccttgg
     3661 aggaatcttc ttcctatttg gaaatgttta taatggaaat atccaacttc ttctggcaac
     3721 cgttatctca acaaattcaa ttgctgaatt ggtcatttct gcaattctaa ccctagccat
     3781 tgttccacga ctacaaacct tgaaaaaata aaaacaatct ccgctttcaa acctgaaggt
     3841 ggagattttg ctctatacag tttcttttta atgaaatctt tactatagta aaacgaaata
     3901 agaacaggat aaatcgatca ggacagccaa atcgatttct aacaatgttt tagaagtaga
     3961 ggtggactat tctagtttca atctactata acttttaact aaaaaatgat ctataaaccc
     4021 aagtaaattc ttgctttatt gtctggttta ttgtaccata ctagtgtata tgcagttaaa
     4081 aaggagattc ttgtgaatac acggaaaaag acacaattta tgacaatgac agccctttta
     4141 acggctattg cgattttgat tccaattgtt atgcctttca agattgtcat tccacctgct
     4201 tcctatactt tggggagcca catcgctatt tttatagcca tgttcttgtc gcccttgatg
     4261 gcagtttttg tcatcctagc ctctagtttt ggatttttga tggctggcta tcccatggtt
     4321 atcgtttttc gggctttttc ccatatatct tttggtgctt taggagctct ttacctacaa
     4381 aaattccccg ataccctaga taaaccaaaa tcttcctggg ttttcaactt tgttttggct
     4441 gttgttcatg cccttgctga agtattagcc tgtgtccttt tttacgcaac ttcgggtacc
     4501 aatgtagaaa acatgttcta tgttctattt gtgctagttg gatttggcac aattatccat
     4561 agtatggtag actatacatt agcactagct gtctataaag tgcttcgaaa acgccgttaa
     4621 aaggaaaagc tatgacaaaa gatcgcaaac aagccctgct ccaactcttg aaagaagctc
     4681 ctaaagccct taatggccaa agtttggcgg aacattttca tgtcacacgt caggtcattg
     4741 tgcaggacat tgcaattttg agagccgatg gcgctcctat cctatccacc aatcgtggct
     4801 acatctataa gcaaattgat accaatcctt atgttcacaa acttttcaaa gtgaaacatg
     4861 aagttgaaga aatcggtcag gaactccttg ctattgtcga taatggtggg catgtccaga
     4921 ataccttgat tgaccatccc gtttatggag aaattgaaac cttgcttaaa ctgtcttgtc
     4981 gcagagatgt gcaacatttt ctagaacaag tcgagcattc tgactttaga cctctatctg
     5041 aattgacaga tggcatccat taccacctag tcgaagccga aacacaacaa gacctccact
     5101 atatcgagga ggccttggag cagctcggtt atttagtaaa ggattagaaa attttctttt
     5161 cccaatcgtc ttctgtacga tgacggtaga aaaactctga tttgtccgga gcttccatca
     5221 tctccatcag aggtagcata tcataggcca gatccaagtt tggaatctgg tctttttgca
     5281 cccaagaaac ttctccctct tctgaagagc gaagggtacc agagaactca gtcgccttat
     5341 aacaaataac aatgtagcgc ccacctgtat ctagtggcca atttttaatg ccgacaagtt
     5401 gaggattttg gatagtcaac cctgtttctt cgtagatttc acgaatgaca gactccgcaa
     5461 aagcctcatc attttctaca tgacctccag gaaaggcata acctgaccag cgattggtgt
     5521 caggagagcg atactgcatg actacgcgct gagtttctaa gtcttcaatc agacaaatat
     5581 tggttaaaat cgttaattgg gaacgggaca taaatttact cgctttctaa tttattaaat
     5641 tttcagactt ggtaccagtg ccattagctt ctacttttta aaattatttt agaatagaat
     5701 accattcgtt tttcctttat aggctttcca agttcaagta tcttttcttg tccatcaaaa
     5761 gtaaaaccca ttttttgata gaaagcaatg gctcgcttgt tatctttcaa tacccataag
     5821 aaaatttcag aaaaatgatt cagagcagtc aaagctgctt tcattaactt ttgtgctatg
     5881 ccttttccgt aatagtcttt taaaacatat aaagcaataa tttcaccagc ttgaatagtc
     5941 tcatcacgaa agttaccata actgataaaa ccaactacct tcagatcacc tatcgcaatc
     6001 aatgtatttt ctggatactt ttgactaaag aatcgacatc tttctaatgt cattgtctcc
     6061 tgaaattctg caggcaaaag gtcatcataa gcctctctcc acgtttgcca gtgaacaagg
     6121 gatttacctt ctatctcttc aggagtttcc attgatttga taataaccgt cattcatttt
     6181 ctcccagtct tctctcaaaa taccatattt aatactatca aaatatttac cttgataata
     6241 acgaactttt ggaatatgag cttctttttt cattcttaat ttttcagcaa gtttcatcat
     6301 accaagattt cctgaccaag ttgtcaaacc cagatgctcc aactccaagt aatcctgaaa
     6361 cgtcctatct atccactgca acatagcaac tttcccaata ccagtgttcc agaatttttt
     6421 atcataaata ccaattccca attccatcca tcttgtttgt ttacataccc aataacgcga
     6481 aacagtccca actagtttat catcaacaaa aataccaagg cgatttgagt tgcttaaaat
     6541 ggattctgat ttttgtagtt cgaattcttt aaaatttgaa aaatactgat aatcatcata
     6601 atagggagca tcatactgtt tccaaactgg attaagttgt gaataagcca tttcccataa
     6661 agacatcaaa tcttctctct ttaactttct taaataaatc atactattcc cctaatccaa
     6721 ggccttgact tccaacatca tatcacggat ctgagccgcc agttcaaagt caagcacttc
     6781 gacggcttct tgcatttgtt tttctagttt cttgacgagt tctttgcgct cttgtttgtt
     6841 gaggctattg atgtcgactt ccttgtcctc ttccttagca actgccttgg tcacggcaat
     6901 caggtcacgg atttctttct tgattgtctg tggtacgata ccatgctctt cattataggc
     6961 catctgaatt ttccgacggc gggcagtttc atcgatagca cgttgcatag actgggtaac
     7021 cgtgtctgca tacatgatga catggccttc actgttacga gcagcacgtc caatagtctg
     7081 gatgagtcca cgttcgttgc gaaggaaacc ttccttgtca gcatcgagaa tagctacgag
     7141 gctcacttca ggaacgtcaa ttccttcacg gagcaggtta attccgacca agacatcaaa
     7201 gacacccaag cgcaggtcac ggataatctc cgtccgttcc aaggtcttga tatccgagtg
     7261 catgtacttg accttgatac ccatttcctt gaagtagtcg gtcaagtcct ctgccatttt
     7321 cttggtcaaa gttgtgataa aggtacgctc atttttttca acgcgggcat tgatttcacc
     7381 caagaggtca tcaatctgtc ccatagtcgg acggacttcc acctctggat ccaagagtcc
     7441 cgttggacga atgatttgct caatcactgt ctcggtctgt tcattttcat agtcaccagg
     7501 tgtcgctgaa acgtaaacaa tctgatgaac gtgactctca aactcctccc gacgtagagg
     7561 acgattgtcc aaagcagacg gcaaacggaa accataatta accagcattt ctttacgcga
     7621 acggtctcca ttgtacatgc ccttgatttg ccctatggtc atatgactct cgtcaatcat
     7681 aatcaagaaa tcatctggga agaagtcgag aagcgtataa ggaggctctc cttcgctccg
     7741 tccatccatg tggcgagaat aattttcaac cccattggta tagcccatct cacgcaacat
     7801 ttcgatatca tactctgtcc gctgtttcaa acgctgggct tcaagcagtt taccttcctt
     7861 ttcaaagaca gctaattgtt cttccaactc ggcctgaatc tttgcaatgg caacttccat
     7921 gtggtcgtca ttggtcacaa agtgtgtcgc tgggaaaatc gctaaatgat ccacttctcc
     7981 caacacctga cctgtcagag cctcaacttc acgaatacgg tcaatttcgt ctccaaaaaa
     8041 ttctactcga aaggcatgtt catctcggga agctgggaaa atctctacca catccccacg
     8101 aacgcgaaat cttccgcgtt ggaaatcaat atcattgcgt tcaaactgaa tatcgaccaa
     8161 gtcattcaag agtttatcac gagaaatctc tagaccagga cggagactaa cgacactatc
     8221 agcgtattcc ttgggcgaac ccaaaccata gatacaagag actgaggcca cgacaataac
     8281 atcattacgc tccaaaaggg ctgaggtagc tgagtggcga agcttgtcaa tctcgtcatt
     8341 gacagaacta tccttctcaa tataggtatc gctagaaggg acataggcct ctggctggta
     8401 ataatcatag taggatacga aatactcaac tgcattttca gggaaaaatt ccttaaactc
     8461 cccatagagc tgaccagcca gagttttatt gtgggcaata accagagttg gtttattgac
     8521 tttagaaatg acctgactca tagtataggt cttccctgtt ccagtcgccc ccatcagaat
     8581 ctgagctttt tctcccccct caatgttatc caccaactgc tcgatagctt ggggttgatc
     8641 tcctgatggt tgatattttg atactagttt aaattgatta tctgtaatgt gattgatcat
     8701 aagaatcctc tctccatgtg ctattcctat tttagcatac ttatagtatt ttcacgaaga
     8761 aaaggacgga ccgaagtcac atcctttcat tttctttctt taatttatta gcaagataga
     8821 caatcagcag tagtaatacc agacttgtca taatggaacc ttctatgcca aaagaaccac
     8881 ctgatagcca atcttgattg ccttgtggta aaaaggtcat cagagacgtt cctgacggtt
     8941 gaccactaac taaaatccca aagagattac cctgagcaaa attccaagca ccatgaatac
     9001 ctgcaacacc ccaaactgta tcagttttga gaagataaag agccatggca actccgaata
     9061 aaaagagatt tactagagat agaggggtga ggccagaatt gcccatatga agcagggtaa
     9121 agaacaggct agatataaga atagctagtt ttagattggt tcttgaggcc aattgaggaa
     9181 gtagccaagc acgggccacc acttcttctg ctgtcccctg taaaatccaa aatgggatag
     9241 taaagacgac aaaggcaaga gaataaggat tcaagtgaat ggattccaaa cgatattgac
     9301 ctaagaccac taaacctaac aaggtcagaa gaaaaagtgc caagcctaga ctaaatcctt
     9361 tcagaagatt gctgaggaaa ttctctctat aaaatcccaa ggttcgaata ggtcttttct
     9421 caacttttct tgtccatctg aacacagtgt taagaataaa accaaaggcc agtaatccta
     9481 aaattaaacg aaagtcactt gttttatccg tcaagctctg atgcaaggtc tgcaagtagg
     9541 ttgcaagatt ttgaccagcc tctccaaaat ttctagcaag tccgatgaga gctaacaagc
     9601 caataccata caaagtaaaa gccacaaact ctcctatgaa gacaaaaaca aaggctaaca
     9661 aggggcttgt gtaaatgttt aaactcattt ttgaagcttg gaagtcttta aatattcttt
     9721 tgttcttcat atccccgtcc tcttttcttc tatatatact attattatag cactttttaa
     9781 tagcaattca agaaagaaaa ggaaaaatca atgttatatt ttctgacacg aaaaatataa
     9841 caatttgcct ttttttactt tttctgatat aatgagagaa tattcggaaa aggagactaa
     9901 aaatgaagaa aaaatttcta gcatttttgc taattttatt cccaattttc tcattaggta
     9961 ttgccaaagc agaaacgatt aagattgttt ctgataccgc ctatgcacct tttgagttta
    10021 aagattcaga tcaaacttat aaaggaattg atgttgacat tattaacaaa gtcgctgaga
    10081 ttaaaggctg gaacattcag atgtcctatc ctggatttga cgcagcagtc aatgcggttc
    10141 aagctgggca agccgacgct atcatggcag ggatgacaaa gactaaagaa cgtgaaaaag
    10201 tcttcaccat gtctgatact tactatgata caaaagttgt cattgctact acaaagtcac
    10261 acaaaattag caagtacgac caattaactg gcaaaaccgt tggtgttaaa aacggaactg
    10321 ccgctcaacg tttccttgaa acaatcaaag ataaatatgg ctttactatt aaaacatttg
    10381 acactggtga tttaatgaac aacagcttga gtgctggtgc catcgatgcc atgatggatg
    10441 acaaacctgt tatcgaatat gccattaacc aaggtcaaga cctccatatt gaaatggatg
    10501 gtgaagctgt aggaagtttt gctttcggtg tgaaaaaagg aagtaaatac gagcacctgg
    10561 ttactgaatt taaccaagcc ttgtctgaaa tgaaaaaaga tggtagtctt gataaaatta
    10621 tcaagaaatg gactgcttca tcatcttcag cagtgccaac tacaactact ctcgcaggat
    10681 taaaagctat tcctgttaag gctaaatata tcattgccag cgattcttct tttgcccctt
    10741 ttgttttcca aaattcaagc aaccaataca ctggtattga tatggaattg attaaggcaa
    10801 tcgctaaaga ccaaggtttt gaaattgaaa tcaccaaccc tggttttgat gctgctatca
    10861 gtgctgtcca agctggtcaa gccgatggta tcatcgctgg tatgtctgtc acagatgctc
    10921 gtaaggcaac ttttgacttc tcagaatcat actacactgc taataccatt cttggtgtca
    10981 aagaatcaag taatattgct tcttatgaag atctaaaagg aaagacagtc ggtgttaaaa
    11041 acggaactgc ttctcaaacc ttcctaacag aaaatcaaag caaatacggc tacaaaatca
    11101 aaacctttgc tgatggttct tcaatgtatg acagtttaaa cactggtgcc attgatgccg
    11161 ttatggatga tgaacctgtt ctcaaatatt ctatcagcca aggtcaaaaa ttgaaaactc
    11221 caatctctgg aactccaatc ggtgaaacag cctttgccgt taaaaaagga gcaaatccag
    11281 aactgattga aatgttcaac aacggacttg caaaccttaa agcaaacggt gaattccaaa
    11341 agattcttga caaataccta gctagcgaat cttcaactgc ttcaacaagt actgttgacg
    11401 aaacaacgct ctggggcttg cttcaaaaca actacaaaca actccttagc ggtcttggta
    11461 tcactcttgc tctagctctt atctcatttg ctattgccat tgtcatcgga attatcttcg
    11521 gtatgtttag cgttagccca tacaaatctc ttcgcgtcat ctctgagatt ttcgttgacg
    11581 ttattcgtgg tattccattg atgattcttg cagccttcat cttctgggga attccaaact
    11641 tcatcgagtc tatcacaggc caacaaagcc caattaacga ctttgtagct ggaaccattg
    11701 ccctctcact caatgcggct gcttatatcg ctgaaatcgt tcgtggtggt attcaggccg
    11761 ttccagttgg ccaaatggaa gccagccgaa gcttgggtat ctcttatgga aaaaccatgc
    11821 gtaagattat cttgccacaa gcaactaaat tgatgttgcc aaactttgtc aaccaattcg
    11881 ttatcgctct taaagataca actatcgtat ctgctatcgg tttggttgaa ctcttccaaa
    11941 ctggtaagat tatcattgct cgtaactacc aaagtttcaa gatgtatgca atccttgcta
    12001 tcttctatct tgtaattatc acacttttga ctagactagc gaaacgctta gaaaagagga
    12061 ttcgttaatg gcaaaattaa aaattgatgt aaatgattta cacaagcact atggaaaaaa
    12121 tgaagtccta aaaggaatta cgactaagtt ctatgaagga gatgttgttt gtatcatcgg
    12181 tccttcaggt tctggtaagt caactttcct ccgtagcctc aatcttttag aagaagtcac
    12241 tagcggtcac atcactgtga acggctatga tttaactgaa aaaacaacca atgttgacca
    12301 cgtccgtgaa aatatcggca tggtattcca acacttcaac ctcttccctc atatgtctgt
    12361 attggacaac atcacctttg ctcctattga gcacaagttg atgactaagg aagaagctga
    12421 gaaattggga atggagttgc ttgaaaaggt tggactagca gataaagcta atgccaatcc
    12481 agatagccta tcaggtggtc aaaaacaacg tgtggccatc gctcgtggcc tagcaatgaa
    12541 tccagacatc atgctcttcg atgaaccaac ttctgccctt gaccctgaga tggttggaga
    12601 cgtacttaac gttatgaagg aattggctga gcaaggcatg accatgatta tcgtaaccca
    12661 tgagatggga tttgctcgtc aggttgccaa ccgcgttatc tttactgcag atggcgagtt
    12721 ccttgaagac ggaacacctg accaaatctt tgataaccca caacaccctc gtctgaaaga
    12781 gttcttagat aaggtcttaa acgtctaaac tcaaactgta aggatttcct tgcagttttt
    12841 cggctctttg tcaactg
//
LOCUS       DAVHBD010000049        11764 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000049 DAVHBD010000000
VERSION     DAVHBD010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.049"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            226..2517
                     /gene="pcrA"
                     /locus_tag="VVK04_001782"
     CDS             226..2517
                     /gene="pcrA"
                     /locus_tag="VVK04_001782"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU3990410.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNTQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2560..3240
                     /gene="radC"
                     /locus_tag="VVK04_001783"
     CDS             2560..3240
                     /gene="radC"
                     /locus_tag="VVK04_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU3990411.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3237..3926)
                     /locus_tag="VVK04_001784"
     CDS             complement(3237..3926)
                     /locus_tag="VVK04_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU3990412.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYASKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3944..4585)
                     /locus_tag="VVK04_001785"
     CDS             complement(3944..4585)
                     /locus_tag="VVK04_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU3990413.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4668..4883)
                     /locus_tag="VVK04_001786"
     CDS             complement(4668..4883)
                     /locus_tag="VVK04_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU3990414.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4891..5238)
                     /locus_tag="VVK04_001787"
     CDS             complement(4891..5238)
                     /locus_tag="VVK04_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU3990415.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5243..6358)
                     /locus_tag="VVK04_001788"
     CDS             complement(5243..6358)
                     /locus_tag="VVK04_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU3990416.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6368..7327)
                     /locus_tag="VVK04_001789"
     CDS             complement(6368..7327)
                     /locus_tag="VVK04_001789"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU3990417.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7440..8009)
                     /locus_tag="VVK04_001790"
     CDS             complement(7440..8009)
                     /locus_tag="VVK04_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU3990418.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8137..8808
                     /locus_tag="VVK04_001791"
     CDS             8137..8808
                     /locus_tag="VVK04_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU3990419.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8792..9610
                     /locus_tag="VVK04_001792"
     CDS             8792..9610
                     /locus_tag="VVK04_001792"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU3990420.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9607..10503
                     /locus_tag="VVK04_001793"
     CDS             9607..10503
                     /locus_tag="VVK04_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU3990421.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHLLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10547..11521
                     /gene="pta"
                     /locus_tag="VVK04_001794"
     CDS             10547..11521
                     /gene="pta"
                     /locus_tag="VVK04_001794"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU3990422.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3423 a         2258 c         2535 g         3548 t
ORIGIN      
        1 tgctggcatt atcaatcatg aactaggatt ctagttttgc aggaagtcta ttgaggtatt
       61 gagctagttt atgaaaaaat tgggtgaaaa agtcgagtgt tttagaaacc cacagtgtag
      121 tattctagtt tcaatccact atattttgct actccccgta aagtttctat tttccctgat
      181 ttctgatata atagaaatat tgacttcaag agtaaggaag agaagatgaa cgcattatta
      241 aatggaatga atgaccgtca ggctgaggcg gtgcaaacga cagaaggtcc cttgctaatc
      301 atggcagggg ctggttctgg aaagactcgt gttttgaccc accgtatcgc ttatttgatt
      361 gatgaaaagc tggtcaatcc ttggaatatc ttggccatta cctttaccaa caaggctgcg
      421 cgtgagatga aagagcgtgc ttatagcctc aatccagcta ctcaggactg tctgattgcg
      481 accttccact ccatgtgtgt gcgtattttg cgtcgagatg cggaccatat tggctacaat
      541 cgtaatttta caattgtgga tcctggtgaa cagcgaacgc tcatgaaacg tattctcaaa
      601 cagttgaact tggatcctaa aaaatggaat gaacgaacta ttttggggac catttccaat
      661 gctaagaatg atttgattga tgatgttgct tatgctgccc aagctggcga tatgtatacg
      721 caaattgtgg cccagtgtta tacaacctat caaaaagaac ttcgtcagtc tgaatccgtt
      781 gactttgatg atttgattat gctgaccttg cgtctctttg atcaaaatcc tgatgttttg
      841 acctactacc agcaaaaatt ccaatacatc cacgttgatg agtaccaaga taccaaccac
      901 gctcagtacc aattggtcaa actcttggct tcccgtttta aaaatatctg tgtggttggg
      961 gatgcggacc agtctatcta cggttggcgt ggtgctgata tgcagaatat cttggacttt
     1021 gaaaaggatt accccaaagc caaggttgtt ttgttggagg aaaattaccg ctcaaccaaa
     1081 accattctcc aagcggccaa cgaggttatt aaaaataata aaaatcgccg tcctaaaaat
     1141 ctctggactc aaaatgctga tggggagcaa atcgtttact atcgtgccga tgatgagctg
     1201 gatgaggctg tatttgtagc cagaaccatc gatgaactta gtcgcagtca aaacttcctt
     1261 cataaggatt ttgcagttct ctatcggact aatgcccagt cccgtacaat tgaggaagcc
     1321 ctgctcaagt ctaacattcc ttataccatg gttggcggaa ccaaattcta cagccgtaag
     1381 gaaattcgcg atattattgc ttatctcaac cttattgcta atttgagtga caatattagt
     1441 tttgagcgta ttatcaacga gcctaaacgt ggaattggtc caggtacagt tgagaaaatc
     1501 cgtgattttg caaatttgca aaatatgtct atgctggatg cttctgctaa tattatgttg
     1561 tctggtatca agggtaaggc agcccaatct atctgggatt ttgccaatat gatgcttgat
     1621 ttgcgggagc agctagacca cttaagcatt acagagttgg ttgagtccgt cctagaaaaa
     1681 acaggttatg tcgatattct taacacccaa gcgactctag aaagcaaggc aagggttgaa
     1741 aatatcgaag agtttctttc tgttacgaag aactttgatg acaccactga tgtgacagaa
     1801 gaggaaactg gtctggacaa actgagtcgt ttcttaaatg acttggcttt gattgccgac
     1861 acagattcag gtagtcagga gacatcagaa gtgaccttga tgaccctgca tgctgccaaa
     1921 ggtctcgaat ttccagttgt ctttttgatt gggatggaag aaaatgtctt tccacttagt
     1981 cgtgcgactg aagatccaga tgaattagaa gaagagcgcc gtctagccta tgtaggtatc
     2041 acgcgtgcag agaaaattct ctatctgacc aatgccaact cacgcttgct ttttggtcgt
     2101 accaattata accgtccgac tcgttttatt aacgaaatca gttcagactt gcttgagtat
     2161 caaggtctgg ctcgtcctgc aaatacaagc tttaaggcat catatagcag tggtagtatt
     2221 tcctttggtc aaggtatgag tttggctcag gctcttcaag accgtaaacg cggtgctgcc
     2281 ccaaaatcaa tccagtcaag cggtcttcca tttggtcaat ttacagctgg cgcaaaacca
     2341 gcatctagcg aggcaaattg gtccattggt gacattgctc tccacaagaa atggggagag
     2401 ggaactgttc tggaagtttc aggtagcggt gctaggcagg aattgaaaat caatttccca
     2461 gaagtaggtt tgaaaaaact tttagccagt gtggctccaa ttgagaaaaa aatctaattt
     2521 tccatccttc tcacgaataa taaagtgagg aggattttta tgtacagtat ttcattccaa
     2581 gaagattcac tattaccaag agaaaggctg gccaaggaag gagttgaagc gcttagtaac
     2641 caagagttgc tagctatttt actcaggaca ggaacacgtc aagctagcgt ttttgaaatt
     2701 gcccaaaaag tcttgaacaa tctttcaagc ctaacggatt tgaaaaaaat gaccctgcag
     2761 gaattgcaga gtttgtctgg tattgggcgt gttaaggcca tagaattaca agctatgatt
     2821 gaactggggc atcgtattca caaacacgag actcttgaaa tggaaagtat tctcagcagt
     2881 caaaagttgg ccaagaagat gcagcaggaa ttaggggata aaaaacaaga gcacctggtg
     2941 gcactctatc tcaatactca aaatcaaatc atccatcagc agaccatttt tatcggttct
     3001 gtaactcgta gtatcgctga accgcgagag attcttcact atgcaatcaa gcatatggcg
     3061 acttctctta tcttggtcca caatcatcct tcaggagcgg tagcgcctag ccaaaatgat
     3121 gatcatgtca ctaaacttgt taaagaagcc tgcgaactga tggggattgt tctcttggac
     3181 catttgattg tctctcattc taattacttt agttatcgtg aaaagacaga tttaatctaa
     3241 agttcattaa cgacatagtc aaagagtttt ttatctttgg gacgattttc aaaaagaagt
     3301 tctggatgcc attggacacc gagaaaggcg acatcatccg tactcatgac agcctcaatg
     3361 ataccatctt taggatcatg agccacaact tttaaatttg gtgctaagtc cttgatgctc
     3421 tggtggtgga aggagttgat atgagagatt tctccataga tttcttggag aacggtatct
     3481 ggttctgtta ccaagcgttg agttgtgtac tcaacagaag aatcctgcca atggtcttcg
     3541 atatcttggt acaaagttcc acccatggca acgttaaaga gttgggtacc acggcagaca
     3601 gagaaaatgg gctttttctg tttaatagct tccttgatga gggccagttc gaagatatct
     3661 ctttgaaggt gatagtcatc gctatcaatg gttttgggtt cgccatagaa ttttggatcg
     3721 acattttgcc cacctgtcaa gatgagcttg tcaatcaaac tgatatagtg gcaggccatt
     3781 tcttgatcac caatcggtag gatgatggga atccctccag catctttaac gccttcaaca
     3841 aagccttttg atgcgtagct catcatgatg tcatcatctg gatgagcttt ttcgtttcct
     3901 gtaatcccaa taactggttt tttcataaaa tgattttcgc tttctaatcc tcttttcgca
     3961 tgaagtagag gagggtttgg agttcacttg tcaaatcgac atactgaacg accacgtctt
     4021 ttggtaaatg cagatggact ggtgaaaaac tgagaattcc tttcacacca gcatcaacca
     4081 agagattagc aacctcttgt gacttgacgc tgggaacagt taggatagca gtcttcacat
     4141 cagcatcctt gattttatcc ttgatctgag aaatcccgta aatgggaatc ccgtcaggag
     4201 tttgggtacc gacttcagga tggtcgtcta ggtcaaaggc catgataatc ttcatcttgt
     4261 tacgttcgtg gaagcggtag tggagaaggg catggcccat atttccaata ccaaccagca
     4321 tgacattggt aatagagttg tcattgagca aatcggcaaa aaatgtcatt agttttttga
     4381 catcatagcc aaaaccacga cgaccaagtt caccaaaata ggaaaaatca cgacgtacgg
     4441 tcgctgaatc aataccgata gcctctgcaa tttgcttaga gttggcacgt tcaatctttt
     4501 ctgcatgaaa tctcttaaaa attcgatagt agagagagag tctttttgct gtagcttttg
     4561 gaatagcaaa ctgtttatct ttcacaaaat cacaaccttt ctattcttct attttataga
     4621 aacattgtga aaaaatcaac aaaaataaga aaaaactaag aaaaatctta gttttgatgt
     4681 aaaaaatctg catgagatag aaaacggtag aggtctccga ccagaccctg ataaactttt
     4741 tggcccctaa aagtcagaga agtcacataa agtgtatctg gtaaggttac acatcctgac
     4801 aaagtcaaca tgagagcctc atgatcctca tacttgagag tacgctctac atgatagcag
     4861 tccttatagg tcagttcaaa cattttggct ctatctttcc gattttgtaa agacaccacg
     4921 ttctaccaag ctatccatga ggaagtagaa tttttcctga tgaatatggt ggtcttctga
     4981 tttgaaaata tcaactagac gaaggccaaa cttgtcagtg atattgattt tagcccctgt
     5041 aagttccttg ttaatgatga ttttgagttg gaagccttca ccgctgtttg gcactttttc
     5101 caaaaggcga gtcagttcat agttaccaac cttagtttca aaaaaggtgt tatctttgag
     5161 ggtgaatttt ttaacagaag ggctaagagt gtaatcgtaa cgacaatttt ttaactgaat
     5221 gattttttca aatgccatat ggctaacctc cgataatttc ttttaaggtt tttgcgaggg
     5281 tttgtaggtc ttcaacggta ttttgtggcg acaaactgat gcgaagggat tccttcaagc
     5341 gttctgaatt tgcgccatac atggcttcaa gaacatggct ggattggaca acgcctgcag
     5401 tacaggctga gccagtagag attgaaattc cagctaaatc tagccgaagg agtaagaggt
     5461 catttttctg accaggaaat ccaatattga gaacataagg gagatgatgt tttcctctat
     5521 tcaagtaata ctgaatgccc tccagctctg ccagaaaggc agtttctaga ttttgtacat
     5581 gttgaaaatg ttcttcttgt ttttctaggt cttcttttag ggctgcaacc atgcctacga
     5641 tagcaggcag attttcagtt cctgcacgtt ttttctgttc ctggtctccg ccatgtagat
     5701 aggaatcaaa gtccatgcta gatgcgtaga gaaaaccgat tcccttagga ccatggaatt
     5761 tgtgggcaga agcagtgaga aaatcaatgc ccaattcttc tgaatgaatt gggattttac
     5821 caatagcctg aactgcatca acatgatagg cagcagggtg ttgcttgagt atttggccaa
     5881 tttcagcgat gggcagtagg tttcctgtct cattattggc aaacatggta gaaaccaaaa
     5941 tcgtatcgtc acgtaaagcc ttttgaattt gctgggctgt gatttcttga ttttctggct
     6001 ggataatggt tgcttcaaac ccaaagtgtt gaaccaagta atcaattgtt tcaaggacag
     6061 catggtgctc gatggcagtt gtgatgatat gttttccttg ttcttggtga cgaagacagt
     6121 agccaatgat ggtagtatta ttgccttcag tcccaccaga agtgaaaaag atatgttgag
     6181 gttttgtcct tagtaactgg gctagttcct gacgggcttc tcgcaagagt ttgccagctt
     6241 gacgaccatg accatgaata ctagaaggat ttccgtgggt ttcttgcata accttggtca
     6301 tagctgaaat agcaactgct gacataggag tcgttgcagc attgtccaaa taaatcaaag
     6361 aatcacctta tttcttttta ttgtaggcaa agagtgggct gactggtttt ctttcgtgaa
     6421 tacggacgat agcatcacca attaactcac tagcagtgat gtagcataca tttttaggag
     6481 ttttttcttt tgttgctact gaatcagtca caagaatttc tttaatatta gtattgtcaa
     6541 gaagctcagc agctccctcg acgaagagac cgtggctaga aacagcataa atttctgtag
     6601 ctccttcacg ttcaacgatt ttagaagctt cagagaaggt acgtcctgta tttaaaatat
     6661 catcaatcaa gatagctttc ttaccttcaa catcaccaat aatataacct tcgttacgag
     6721 ttgcatcgtc ttgagggtag tcgataatgg cgataggagc atcaagatat tcagccaggc
     6781 tacgcgcacg tttgacacct gaatttttag ggctaacgac aacaacatct gaaccaagca
     6841 atcctttatc gcagtaatgt tttgcgaata ggggaacagt gaaaagatta tccactggaa
     6901 tatcaaagaa accttgaacc tgaacggcat gcaaatcaag agtcaggata cgatcaactc
     6961 cagccttaac cagcatattg gcaactagtt ttgctgtaag tggctcacga ggacaagcaa
     7021 tgcggtcttg acgtgcatag ccaaaatatg gaaggacaac gttgatactg tgggcacttg
     7081 cacgcacaca agcatcgacc atgattaaca attccattag gtggttgttg acagggaaac
     7141 ttgttgattg gatgatgtaa acatcataac cacggacact ttcttcgata tttacttgga
     7201 tttctccgtc tgaaaattga cgtgatgata gttttccaag tgggacacca acagcttggg
     7261 caattttttg tgcaatctct tggttagagt tgagtgcgaa aagtttcatg ttttttctat
     7321 ctgacattat agaccgtcct ctgtaaactt tataaatcct agttatattt accttacata
     7381 tatgaactgg gatttgtgta tttttatctt ttctatttta ccaaaaaatg gagattattt
     7441 cagctatttt tcatactttt gacaaatcga accaattttg aaggagcttt ttggtaggaa
     7501 atctgatttt tctctaaaaa ttgtcggaaa tcctgtttgc cttgctcatg attttccact
     7561 tcaagctcca attcgtaatc tgttatatca aagtatcggc tctgatccag tgccatgaga
     7621 ccaatagctg ttttcatttc atagcgaagc gttgttagac aaccaagaac ctgccagttc
     7681 ttactttgga taccatgttt cgccaattca tccagtacta gcccttgagg aagttcttcc
     7741 ttactcagat agttctcagc atcttttagt tgcaattttt ggttgtattc catgtttcca
     7801 acactctgcg ggactttgag tgtcaactca gcccagtctt caaaggttcg aatgcgcata
     7861 gcgactttct tttctcgcag ttcaaaatca ggcgtgtcga tgtagtaatt tgtttgaaga
     7921 acaggagtga cacctgtgaa ctggtctttt agacgattgt attcatcttt tttcaatagt
     7981 gttttcaatt caatttctaa atgtttcatt tttcttacct ttttttatcg ttgaaagcgg
     8041 atttatggta taataagcat tgtatttatt gtatatgaat ctggagaaaa aatcaaagat
     8101 atttttgacg gataatatga gaacaaggga gaatatatga ccttagaatg ggaagaattt
     8161 ctagatcctt acattcaagc tgttggtgag ttaaagatta aacttcgtgg tattcgtaag
     8221 caatatcgta agcaaaataa gcattctcca attgagtttg tgaccggtcg agtcaagcca
     8281 attgagagca tcaaagaaaa aatggctcgt cgtggcatta cttatgcgac cttggaacac
     8341 gatttgcagg atattgctgg cttacgtgtg atggttcagt ttgtagatga cgtcaaggaa
     8401 gtagtggata ttttgcacaa gcgtcaggat atgcgaatca tacaggagcg agattacatt
     8461 actcatagaa aagcatcagg ctatcgttcc tatcatgtgg tagtagaata tacggttgat
     8521 accatcaatg gagctaagac tattttggca gaaattcaaa ttcgtacttt ggccatgaat
     8581 ttctgggcaa cgatagaaca ttctctcaac tacaagtacc aaggggattt cccagatgag
     8641 attaagaagc gactggaaat tacagctaga atcgcccatc agttggatga agaaatgggt
     8701 gaaattcgtg atgatatcca agaagcccag gcactttttg atcctttgag tagaaaatta
     8761 aatgacggtg taggaaacag tgacgataca gatgaagaat acaggtaaac gaattgatct
     8821 gatagccaat agaaaaccgc agagtcaaag ggttttgtat gaattgcgag atcgtttgaa
     8881 gagaaatcag tttatactca atgataccaa tccggatatt gtcatttcca ttggcgggga
     8941 tggtatgctc ttgtcggcct ttcataagta cgaaaatcag cttgacaagg tccgctttat
     9001 cggtcttcat actggacatt tgggcttcta tacagattat cgtgattttg agttggacaa
     9061 gctagtgact aatttgcagc tagatactgg ggcaagggtt tcttaccctg ttctgaatgt
     9121 gaaggtcttt ctcgaaaatg gtgaagttaa gattttcaga gcactcaacg aagccagcat
     9181 ccgcaggtct gatcgaacca tggtggcaga tattgtaata aatggtgttc cctttgaacg
     9241 ttttcgtgga gacgggctaa cagtttcgac accgactggt agtactgcct ataacaagtc
     9301 tcttggcggt gctgttttac accctaccat tgaagctttg caattaacgg agattgccag
     9361 ccttaataat cgtgtctatc gaacactggg ctcttccatt attgtgccta agaaggataa
     9421 gattgaactt attccaacaa gaaacgatta tcatactatt tcggttgaca atagcgttta
     9481 ttctttccgt aatattgagc gtattgagta tcaaatcgac catcataaga ttcactttgt
     9541 cgcgactcct agccatacca gtttttggaa ccgtgttaag gatgccttta tcggtgaggt
     9601 ggatgaatga ggtttgaatt tatcgcagat gaacatgtca aggttaagac ctttttaaaa
     9661 aagcacgagg tttctaaggg attgctggcc aagattaagt ttcgaggtgg agctattctg
     9721 gtcaataatc aaccgcaaaa tgcaacgtat ctattggacg ttggagacta cgttaccatt
     9781 gacattcccg ctgaggaagg ctttgaaacc ttggaggcta ttgagcatct attagatatt
     9841 ctctatgagg atgatcactt tctagtcttg aataaaccct atggagtggc ttctattcct
     9901 agtgtcaatc actctaatac cattgccaat tttatcaagg gttactatgt caagcaaaat
     9961 tatgaaaatc agcaggttca cattgttacc agactagata gggacacttc tggcttgatg
    10021 ctctttgcca agcacggtta tgcccatgca cgattagaca agcagttgca gaagaaatct
    10081 atcgagaaac gctactttgc tttggttaag ggagatggac atttggagcc agaaggggaa
    10141 attattgctc cgattgcgcg tgatgaagat tccattatta ccagacgagt ggctaaaggc
    10201 ggaaagtatg cccatacttc atacaagatt gtagcttctt atggaaatat tcacttggtc
    10261 tatattcacc tgcacactgg tcgaacccat caaatccgag tccatttttc tcatatcggt
    10321 tttcctttgc tgggagatga tttgtatggt ggtagtctgg aagatggtat tcaacgtcag
    10381 gctctgcatt gccattacct atccttttat catccatttt tagagcaaga cttgcagtta
    10441 gaaagtccct tgccggatga tttcagtaac cttattaccc agttatcaac taatactcta
    10501 taaaaactgt ctcagagtat aattattatc ttaaaggaga aaactcatgg aagtttttga
    10561 aagtctcaaa gccaaccttg ttggtaaaaa tgctcgtatc gttctccctg aaggggaaga
    10621 gcctcgtatt cttcaagcaa caaaacgctt agtaaaagaa acagaagtga ttcctgtttt
    10681 gcttggaaat cctgaaaaaa ttaaaattta tcttgaaatt gaaggaatca tggatggtta
    10741 tgaggtcatc gaccctcaac attatcctca atttgaagaa atggtttctg ccttggtgga
    10801 gcgtcgcaag ggcaaaatga ctgaagaaga tgtacgcaag gttttggttg aagatgtcaa
    10861 ctactttggt gtgatgttgg tttacttggg cttggttgat ggaatggtgt caggagcgat
    10921 tcactcaaca gcttcaacag ttcgtccagc tctacaaatc atcaaaactc gtccaaatgt
    10981 aactcgtact tcaggagcct tcctcatggt tcgtggtacg gaacgttacc tatttggaga
    11041 ctgtgccatt aacatcaatc cagatgcaga agccttggct gaaattgcca tcaactcagc
    11101 aatcacagct aagatgtttg gcatcgaacc taaaattgcc atgttgagct attctactaa
    11161 aggttcaggg tttggtgaaa gcgttgataa ggtcgttgaa gcaactaaaa ttgctcacga
    11221 cttgcgtcct gaccttgaaa tcgatggtga gttgcaattt gatgcagcct ttgttcctga
    11281 aactgcagct ctgaaagctc ctggaagtac ggtagctggt caagcaaatg tcttcatctt
    11341 cccaggtatc gaggcaggaa atatcggtta caagatggct gaacgcctgg gtggctttgc
    11401 ggctgtagga cctgttttgc aaggtttaaa caagccagtt aatgatcttt ctcgtggatg
    11461 taatgcagat gatgtttaca agttgaccct catcacagca gctcaagcag ttcatcaata
    11521 gtgaaaacta taaagcgata tactatgcta tactgtagtt atgaaactat gtacgaaaag
    11581 cactgccatt aattcctgag aactaaatta ctgattggtg tcaaaaagga aaacttccaa
    11641 gcgataatat cctgtctata cacgacctat agaaatctgt aatatacatg tccgtaaaac
    11701 gataaattcc ctttttgatt ttaaatgagt atgaaaagag aattttttga ctctttgtca
    11761 actg
//
LOCUS       DAVHBD010000050        11706 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000050 DAVHBD010000000
VERSION     DAVHBD010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11706
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.050"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            720..1712
                     /locus_tag="VVK04_001795"
     CDS             720..1712
                     /locus_tag="VVK04_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3990423.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VVK04_001796"
     CDS             1714..2532
                     /locus_tag="VVK04_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU3990424.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VVK04_001797"
     CDS             2534..3319
                     /locus_tag="VVK04_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990425.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLILISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VVK04_001798"
     CDS             3417..3635
                     /locus_tag="VVK04_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU3990426.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3817
                     /locus_tag="VVK04_001799"
     CDS             3620..3817
                     /locus_tag="VVK04_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3990427.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4247..4324)
                     /locus_tag="VVK04_001800"
                     /pseudo
     CDS             complement(4247..4324)
                     /locus_tag="VVK04_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4557..10991
                     /locus_tag="VVK04_001801"
     CDS             4557..10991
                     /locus_tag="VVK04_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU3990428.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            11618..>11706
                     /locus_tag="VVK04_001802"
     CDS             11618..>11706
                     /locus_tag="VVK04_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HEU3990429.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVAT"
BASE COUNT         4098 a         1749 c         2337 g         3522 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta caaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tatttcatga
      541 gagaaatcct aatttcacaa ttcataggta aacgcttgca ttctgttttt tattggacta
      601 taataggttg gtataaagcc ttctgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aacattttgt gaagattgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agattaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaaa tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccgttttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggggagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatatt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgct gagattttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca aacctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaagcttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagc ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt cctcaactat ggaatccgca
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctatttttta
     3841 ttctcagagt gctatactgt aagtgtaatc gccgatttag cttagttggt agagcaaggc
     3901 actcgtaaag cctaggttat aggtagataa acgactgagg atttgaaaaa atagataggt
     3961 agaagataac cgttaagcct tactcttagc ggttatttat attgtttaat agcgctgata
     4021 tttcatcaat tatgcctgtt ttcgtgtttc tagtagttgt tcaagtttat tgctactatt
     4081 tttgatggta tgaatgtgct tataatgtat cccggttaac gaaagttttg gacttatact
     4141 cttagaaaat ctcttcaaac cacgtcaacg tcgccttgcc gtgcgtatgg ttactgactt
     4201 cgtcagttct atccacaacc tcaaaacagt gttttgagct gacttcgtca gttctatcta
     4261 caacctcaaa acagtgtttt gagcaacctg cggctagttt cctagtttgc tctttgattt
     4321 tcattgagta ctaatcttat tttttaacgt gtgctaaaaa ataaattaat gcaggttaat
     4381 ttttcttgaa ttaaattttt ttaaatgata tactgttttt atggagagat aacaattata
     4441 tataaatgta ctactctatt tcctagataa tacttagtaa aactttttat aacaaaggct
     4501 agcaaagtta aagtttatta tctattggaa gttaaataaa tatgtaagga attaaaatga
     4561 aaaaaagtac agtattgtca ttaaccacag ctgcagttat tttagcagcc tatgccccta
     4621 atgaggtagt cttagcagac acatctagct ctgaagatgc tttaaacatc tctgataaag
     4681 aaaaagtagt agtagataag gaaacagaaa ataaagagaa acatgaagat attcataatg
     4741 ctatagaaac ttcacaggat tttaaagaga agaaaacagc agtcattgag ggaaaagaag
     4801 ttgttagtaa aaatcctgtg acagacaata acactagcaa tgaagaagca agaatcaaag
     4861 aagattccaa tcaatcccaa ggagatcata cggactcatt tgtgaataaa aacacagaaa
     4921 atcccaaaaa agaagataaa gttgtctata ttgctgaatt taaagataaa gaatctggag
     4981 aaaaagcaat caagcaacta tccaatctta agaatacaaa agttttatat acttatgata
     5041 gaatttttaa cggtagtgcc atagaaacaa ctccagataa cttggacaaa attaaacaaa
     5101 tagaaggtat ttcatcggtt gaaagggcac aaaaagtcca acccatgatg aatcatgcca
     5161 gaaaggaaat tggagttgag gaagctattg attacctaaa gtctatcaat gctccgtttg
     5221 ggaaaaattt tgatggtaga ggtatggtca tttcaaatat cgatactgga acagattata
     5281 gacataaggc tatgagaatc gatgatgatg ccaaagcctc aatgagattt aaaaaagaag
     5341 acttaaaagg aactgataaa aattattggt tgagtgataa aatccctcat gcgttcaatt
     5401 attataatgg tggcaaaatc actgtagaaa aatatgatga tggaagggat tattttgacc
     5461 cacatgggat gcatattgca gggattcttg ctggaaatga tactgaacaa gatatcaaaa
     5521 actttaacgg catagatgga attgcaccta atgcacaaat tttctcttac aaaatgtatt
     5581 ctgacgcagg atctgggttt gcgggtgatg aaacaatgtt tcatgctatt gaagattcta
     5641 tcaaacacaa cgttgatgtt gtttcggtat catctggttt tacaggaaca ggtcttgtag
     5701 gtgagaaata ttggcaagct attcgggcat taagaaaagc aggcattcca atggttgtcg
     5761 ctacgggtaa ctatgcgact tctgcttcaa gttcttcatg ggatttagta gcaaataatc
     5821 atctgaaaat gaccgacact ggaaatgtaa cacgaactgc agcacatgaa gatgcgatag
     5881 cggtcgcttc tgctaaaaat caaacagttg agtttgataa agttaacata ggtggagaaa
     5941 gttttaaata cagaaatata ggggcctttt tcgataagaa taaaatcaca acaaatgaag
     6001 atggaacaaa agctcctagt aaattaaaat ttgtatatat aggcaagggg caagaccaag
     6061 atttgatagg tttggatctt aggggcaaaa ttgcagtaat ggatagaatt tatacaaagg
     6121 atttaaaaaa tgcttttaaa aaagctatgg ataagggtgc acgcgccatt atggttgtaa
     6181 atactgtaaa ttactacaat agagataatt ggacagagct tccagctatg ggatatgaag
     6241 cggatgaagg tactaaaagt caagtgtttt caatttcagg agatgatggt gtaaagctat
     6301 ggaacatgat taatcctaat aaaaaaactg aagtcaaaag aaataataaa gaagatttta
     6361 aagataaatt ggagcaatac tatccaattg atatggaaag ttttaattcc aacaaaccga
     6421 atgtaggtga cgaaaaagag attgacttta agtttgcacc tgacacagac aaagaactct
     6481 ataaagaaga tatcatcgtt ccagcaggat ccacatcttg ggggccaaga atagatttac
     6541 ttttaaaacc cgatgtttca gcacctggta aaaatattaa atccacgctt aatgttatta
     6601 atggcaaatc aacttatggc tatatgtccg gaactagtat ggcgactcca atcgtagcag
     6661 cttctactgt tttgattcga ccaaaattga aggaaatgct tgaaaaaccc gtattaaaaa
     6721 atcttaaagg tgatgataaa atagacctta caagtcttac aaaaatagcc ctacaaaata
     6781 ctgcaagacc tatgatggat gcaacttctt ggaaagaaaa aagtcaatac tttgcatcac
     6841 ctagacagca gggggcgggg ctaattaatg tggccaacgc tttgagaaat gaagttgtag
     6901 cgactttcaa aaacacggat tctaaaggtt tggtaaattc atatggttcc atttctctta
     6961 aagaaataaa aggtgataaa aaatacttta caattaagct tcacaataca tccaacaggc
     7021 ctttaacctt taaagtttca gcatcagcgg taactacaga ttctctaact gacagattaa
     7081 aacttgatga aacatataaa gatgaaaaat ctccagatgg taagcaaatt gttccagaaa
     7141 ttcacccaga aaaagtcaaa ggagcaaata tcacatttga gcatgatact ttcactatag
     7201 gcgcaaattc tagctttgat ttgaatgcgg ttataaatgt tggagaggcc aaaaacaaaa
     7261 ataaatttgt agaatcattt attcattttg agtcagtgga agaaatggaa gctctaaact
     7321 ccaacgggaa gaaaataaac ttccaacctt ctttgtcgat gcctctaatg ggatttgctg
     7381 ggaattggaa ccacgaacca atccttgata aatgggcttg ggaagaaggg tcaagatcaa
     7441 aaacactggg aggttatgat gatgatggta aaccgaaaat tccaggaacc ttaaataagg
     7501 gaattggtgg agaacatggt atagataaat ttaatccagc aggagttata caaaatagaa
     7561 aagataaaaa tacaacatcc ctggatcaaa atccagaatt atttgctttc aataaccaag
     7621 ggatcaacgc tccatcatca agtggttcta agattgctaa catttatcct ttagattcaa
     7681 atggaaatcc tcaagatgct caacttgaaa gaggattaac accttctcca cttgtattaa
     7741 gaagtgcaga agaaggattg atttcaatag taaatacaaa taaagaggga gaaaatcaaa
     7801 gagacttaaa agtcatttcg agagaacact ttattagagg aattttaaat tctaaaagca
     7861 atgatgcaaa gggaatcaaa tcatctaaac taaaagtttg gggtgacttg aagtgggatg
     7921 gactcatcta taatcctaga ggtagagaag aaaatgcacc agaaagtaag gataatcaag
     7981 atcctgctac taagataaga ggtcaatttg aaccgattgc agaaggtcaa tatttctata
     8041 aatttaaata tagattaact aaagattacc catggcaggt ttcctatatt cctgtaaaaa
     8101 ttgataacac cgcccctaag attgtttcgg ttgatttttc aaatcctgaa aaaattaagt
     8161 tgattacaaa ggatacttat cataaggtaa aagatcagta taagaatgaa acgctatttg
     8221 cgagagatca aaaagaacat cctgaaaaat ttgacgagat tgcgaacgaa gtttggtatg
     8281 ctggcgccgc tcttgttaat gaagatggag aggttgaaaa aaatcttgaa gtaacttacg
     8341 caggtgaggg tcaaggaaga aatagaaaac ttgacaaaga cggaaatacc atttatgaaa
     8401 ttaaaggtgc gggagattta aggggaaaaa tcattgaagt cattgcatta gatggttcta
     8461 gcaatttcac aaagattcat agaattaaat ttgctaatca ggctgatgaa aaggggatga
     8521 tttcctatta tctagtagat cctgatcaag attcatctaa atatcaaaag cttggcgaga
     8581 ttgcagaatc taaatttaaa aatttaggaa atggaaaaga gggtagtcta aaaaaagata
     8641 caactggggt agaacatcat catcaagaaa atgaagagtc tattaaagaa aaatctagtt
     8701 ttactattga tagaaatatt tcaacaatta gagactttga aaataaagac ttaaagaaac
     8761 tcattaaaaa gaaatttaga gaagttgatg attttacaag tgaaactggt aagagaatag
     8821 aggaatacga ttataaatac gatgataagg gaaatattat tgcttatgac gatggtagtg
     8881 ccttacaata tgaaactgaa aaacttgacg aaataaaatc aaaaatttat ggtgttctaa
     8941 gcccatctaa agatggacac tttgaaattc ttggaaagat aagcaatgtt tctaaaaatg
     9001 ccaaggtata ttatggaaat agctataaat cgatagaaat caaagcgact aagtatgatt
     9061 cacattcaaa aacgatgata tttgatttat acgctaatat taatgatatt gtagatggat
     9121 tagcttttgc tggagatatg agattatttg ttaaagatga caatcaaata aaagctgaaa
     9181 ctaagattag aatgcctgaa aaaaataagg aaactaaagc agaatatccc tatgtatcaa
     9241 gttatgggaa tgtaatcgaa ttaggagaag gagatctttc aaagaacaaa ccagacaatt
     9301 taactaaaat ggaatctggt aaaatctatt ctgattcaga aaaacaacaa tatctgttaa
     9361 aggataacat cattctaaga aaaggctatg cactaaaagt gactacctat aatcctggaa
     9421 aaacggatat gttagaagga aatggagtct atagcaagga agatatagca aaaatacaaa
     9481 aggccaatcc taatctaaga gtcctttcag aaacaacaat ttatgctgat agtagaaatg
     9541 ttgaagatgg aagaagtacc caagctgtat taatgtcggc tttggacggc tttaacatta
     9601 taaggtatca agtgtttaca tttaaaatga acgataaagg ggaagctatc gataaagacg
     9661 gaaatcttgt gacagattct tctaaacttg tattatttgg taaggatgat aaagaataca
     9721 ctggagagga taagtccaat gtagaagcta taaaagaaga tggctccatg ttatttattg
     9781 ataccaaacc agtaaacctt tcaatggata agaactactt taatccatct aaatctaata
     9841 aaatttatgt acgaaatcca gaattttatt taagaggtaa gatttctgat aagggtggtt
     9901 ttaactggga attgagagtt aatgaatcgg ttgtagataa ttatttaatc tacggagatt
     9961 tacacattga taacactaga gattttaata ttaagctgaa tgttaaagac ggtgacatca
    10021 tggactgggg aatgaaagac tataaagcaa acggatttcc agataaggta acagatatgg
    10081 atggaaatgt ttatcttcaa actggctata gcgatttgaa tgctaaagca gttggagtcc
    10141 actatcagtt tttatatgat aatgttaaac ccgaagtaaa cattgatcct aagggaaata
    10201 ctagtatcga atatgctgat ggaaaatctg tagtctttaa catcaatgat aaaagaaata
    10261 atggattcga tggtgagatt caagaacaac atatttatgt aaatggaaaa gaatatacat
    10321 catttgatga tattaaacaa ataacagaca agacactaaa cattaagatt gttgtaaaag
    10381 attttgcaag aaatacaacc gtaaaagaat tcattttaaa taaagatacg ggagaggtaa
    10441 gtgaattaaa acctcatagg gtaactgtga ccattcaaaa tggaaaagaa atgagttcaa
    10501 cgatagtgtc ggaagaagat tttattttac ctgtttataa gggtgaatta gaaaaaggat
    10561 accaatttga tggttgggaa atttctggtt tcgaaggtaa aaaagacgct ggctatgtta
    10621 ttaatctatc aaaagatacc tttataaaac ctgtattcaa gaaaatagag gagaaaaagg
    10681 aggaagaaaa taaacctact tttgatgtat cgaaaaagaa agataaccca caagtaaacc
    10741 atagtcaatt aaatgaaagt cacagaaaag aggatttaca aagagaagat cattcacaaa
    10801 aatctgattc aactaaggat gttacagcta cagttcttga taaaaacaat atcagtagta
    10861 aatcaactac taacaatcct aataagttgc caaaaactgg aacagcaagc ggagcccaga
    10921 cactattagc tgccggaata atgtttatag taggaatttt tcttggattg aagaaaaaaa
    10981 atcaagatta agacaaaagc tatagaaaaa aatggtttat gtactgagat tagatagtga
    11041 ggtgatgaca tagttttgtg aaaacagcca tttataactc aattatttag tttacttcac
    11101 tattgatact atttggagtt attaatggac ttagtttaga taactaatga attgattgca
    11161 agggttagta ttgacaatat tggtcatatt gattagaaaa tagagtctat caaaatttaa
    11221 aggctaatag aggtgatgag acaatttcaa ggaattaagt agcgtttggt tgcttaattc
    11281 ctttttattt ggaaggaagt ttttcgtaac cgcccaataa cgaagtctat tggacggtta
    11341 cgatatgatc actgacttcg tcagttctat ctacaaccta aaaacagtgt tttgaacaac
    11401 ctgcggctag cttcctagtt tgctctttga ttttcattga atattagaac agcaaaaatg
    11461 cttgaagtat ttgtttgtgt ttttattttt atataacaaa ctataaacaa aacaaaaata
    11521 taaaaaaaga gacaaaaaag aacagaaagt aattgacaac ggtttcatat agtgttatac
    11581 ttatggcata aagttaatgg aaagaaggga aaaacttatg gtattagatt atttctttga
    11641 caaaaacctt gtgttttgct tagaagcgga taatcaagaa caactctttg atcaggttgc
    11701 aacttt
//
LOCUS       DAVHBD010000051        11261 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000051 DAVHBD010000000
VERSION     DAVHBD010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11261
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.051"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(48..1937)
                     /locus_tag="VVK04_001803"
     CDS             complement(48..1937)
                     /locus_tag="VVK04_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU3990430.1"
                     /translation="MKKTFFLLMFGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQR
                     LKGNRLEEFNKIEDSIVREKEQSKQLLTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2075..3640
                     /locus_tag="VVK04_001804"
     CDS             2075..3640
                     /locus_tag="VVK04_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU3990431.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3640..4380
                     /locus_tag="VVK04_001805"
     CDS             3640..4380
                     /locus_tag="VVK04_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU3990432.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDISHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(4489..4704)
                     /locus_tag="VVK04_001806"
     CDS             complement(4489..4704)
                     /locus_tag="VVK04_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990433.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(5576..6826)
                     /gene="ilvA"
                     /locus_tag="VVK04_001807"
     CDS             complement(5576..6826)
                     /gene="ilvA"
                     /locus_tag="VVK04_001807"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU3990434.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(6876..7232)
                     /locus_tag="VVK04_001808"
     CDS             complement(6876..7232)
                     /locus_tag="VVK04_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU3990435.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7470..7706)
                     /locus_tag="VVK04_001809"
     CDS             complement(7470..7706)
                     /locus_tag="VVK04_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990436.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7813..8835)
                     /gene="ilvC"
                     /locus_tag="VVK04_001810"
     CDS             complement(7813..8835)
                     /gene="ilvC"
                     /locus_tag="VVK04_001810"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU3990437.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPSLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(8901..9377)
                     /gene="ilvN"
                     /locus_tag="VVK04_001811"
     CDS             complement(8901..9377)
                     /gene="ilvN"
                     /locus_tag="VVK04_001811"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU3990438.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9370..11070)
                     /locus_tag="VVK04_001812"
     CDS             complement(9370..11070)
                     /locus_tag="VVK04_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU3990439.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
BASE COUNT         3399 a         2556 c         1939 g         3367 t
ORIGIN      
        1 ttctatcttc cattatatca tactttttca gtctatggta gctctcttta aaaggcaccg
       61 atactgccgc ctcctccgcc tccagagaag ccaccaccag aacttccact tccagaagat
      121 acagagtagg tgcttgctgt atttgcgaca ctagcataat ggctcatttg tgctgttgaa
      181 tgataaaaca tactgtgcca gccataagct acatagagat tgatatctgg attttccact
      241 tgaatctgat gaaccttcat caaatgacta accttgtccg catagccaaa taaggtcgca
      301 tagaccaaga ggcgattcca gaccacaata ctttccagtt cagcctgatc caatcgtgca
      361 atctcacgca acatattttc aaaactggtc cagagatagt agacctcagc tcccgcttca
      421 tttagaacac catcacgatt atctagtcga agcttccaat aatagaaaac agacaaaact
      481 aaccctagaa aaccaagtat tggcaaaggg aggtaaagat agccatgaac gtctaaactg
      541 tacaagaaca aaccaaatcc gataaatagg ggcaggatag tcaaggcacc catacccact
      601 tgcaaggcct tttccccacc agttaaagga cgataataat ctgggagccc ccagaaggaa
      661 actcgttttc tcactccttc ttgcatctgg ttcaatacct cttcaaaaga agatttgagt
      721 tgaagccctc ttgcttgaat ccgtttttca tcagaaactt tggctctacg ataaagacta
      781 tcagatacct tgtaatccgc aaacaaattg gaaagagttt cttctttttt acctgaaaaa
      841 gctagattta ggcagtcttt ctcaaagctt gacaaaccat cttcttttac tagcctcaaa
      901 ccaactgcat ctccttctga aatgatagag acattcccac ggtctatcac atctagcaag
      961 gtagcttgaa taagttgatc aaaggtgaat tttccagctc ccttgaccaa gggactcact
     1021 tcctccaagg aggtcgagta gactgcttct gataaaacca taggctctaa ttccattggt
     1081 ggttcataga gacgatgatt tttggcatat ttgactgaag gagtggtctt tcttctataa
     1141 ataaaataga agcagacact caataacaag gagatggaaa ggatcgaagg gaggacccaa
     1201 gtaagtagtt gtttactttg ctctttttct ctaacaatcg agtcttctat cttattaaac
     1261 tcttctaatc gattcccttt caatctctga tccctagcgc tagcaaaatc ggtccgaggc
     1321 caataggcat gcaactcaac tccacgctta gccggaagat tgtctaaacg gatagtataa
     1381 tcaaggttac tcttttcaat cgttccctct ctaaaaagtt tccctgtatg gaaaaagagt
     1441 ttttcagccc ccttgtctcc ccttacatga aattcaaact tttcaataga ctctgaacta
     1501 tctgtcagag gttgccaatt taattcagcg atatcatcat aaaggaaaag taaatttttt
     1561 aagttccaga cgaggtcaac ttcaactatg tcgccctcct gacctggatt atagactctc
     1621 acagtataac catccgcttc ttctgttact tcgctagtca catctgctag ttctgcaccg
     1681 tttttcgcgg cctgaacctt tggatgaggg tcaatgtcaa acccgctagg catcttacca
     1741 gcacgtccaa gtcccacgat ttgtccctta aagtcctcct caaactgata aactatcttt
     1801 tgtctaaatt ctgccgtatt gtctgcatga atatacaaat caccttgata agagtttatc
     1861 ttaaaatcaa tggcgaaaac agaaagtggc agaaggcaaa acaagccaaa catcagtaag
     1921 aaaaaagttt ttttcatcaa ttaagccccc tttttatctt tcttatcatt atagcatttt
     1981 ttcgtaagta aaggcttact tatgttgaaa aattacgcat ttttcgataa aataggagac
     2041 agttattttt taatagatca gaataggaga aatcatgaga aaaatatact tatctatttt
     2101 cacaagtctc ttgctgatgc taggacttgt caatgttgct caagccgatg aatatttacg
     2161 catcgggatg gaagcagcat atgctccctt taactggacc caggatgatg atagcaacgg
     2221 agctgtcaaa atcgatggta ccaatcagta tgccaacgga tacgatgttc aaatcgccaa
     2281 aaaaatcgct aaggacttag gtaaagaacc tttggttgtt aaaaccaagt gggaaggtct
     2341 agtccctgcc cttacttctg gtaagattga catgattatc gcaggtatga gtccaactgc
     2401 agaacgcaaa caagaaattg ccttttcgag cagttactac actagcgaac cagttttgct
     2461 tgtcaaaaaa gattctgcct acgcaagtgc taaatctttg gatgacttta atggtgcgaa
     2521 aatcacttct caacaaggtg tctacctcta cgacttgatt gcacaaatcc caggtgctaa
     2581 aaaagaaaca gccatgggag acttcgctca aatgcgacaa gctcttgagg ctggtgtcat
     2641 tgatgcttat gtttctgaac gtccagaagc actgactgct gaagctgcga actctaagtt
     2701 caagatgatt caagtagaac ctggtttcaa aactggggaa gaagatacag ctatcgctat
     2761 cgggcttcgt aaaaatgaca atcgtattag ccaaatcaat gccagcattg aaaccatttc
     2821 aaaagatgac caagttgcct tgatggatcg tatgatcaag gaacaacctg ccgaagctac
     2881 aacaactgaa gagactagca gtagtttctt tagccaagtc gctaaaattc tttctgaaaa
     2941 ctggcaacaa ctcttgcgtg gtgctggtat cactctttta atctctatcg tcggaaccat
     3001 cataggtctc attattggac ttgccattgg tgtcttccgt actgctcctc tctctgaaaa
     3061 caaagccatt tatggccttc aaaaactagt cggctgggtt ctcaatgtct acattgaaat
     3121 tttccgtggt acgccaatga ttgttcaatc gatggttatc tactatggaa ctgcccaagc
     3181 tttcgggatc aaccttgacc gtacactggc tgctatcttc atcgtttcaa tcaataccgg
     3241 tgcctacatg actgaaatcg tccgtggtgg tatcctagca gttgacaagg gacaatttga
     3301 agctgcgact gctcttggta tgacccataa ccagaccatg cgtaagattg tcctacctca
     3361 ggtagtccgt aacatcctac ctgcaactgg taatgaattt gtcatcaata tcaaagatac
     3421 atctgtattg aacgttatct ctgttgtcga actttatttc tcaggaaata ccgtggcaac
     3481 acaaacctat caatacttcc agacatttac aatcatcgcc gtgatttact ttgtcctcac
     3541 cttcaccgta acacgtatcc tacgatttat cgagcgccga atggacatgg atacctatac
     3601 tacaggtgct aaccaaatgc aaacggagga tttgaaataa tgacacaagc aatccttgaa
     3661 attaaacacc tcaaaaaatc ctatggacaa aacgaagtgc taaaagacat ttcactcact
     3721 gtccacaagg gagaggtcat ctctatcatc ggaagctctg gaagcggaaa atcgaccttc
     3781 ctacgctcca ttaacctact tgaaacacca actgatggac aaatccttta tcatggacaa
     3841 aacgtcctcg aaaaaggcta tgacctcacg caataccgtg aaaagttggg gatggttttc
     3901 caatccttta acctctttga aaatctcaat gttcttgaaa acacaatcgt cgctcagaca
     3961 actgtcctaa aacgcgaacg cacagaagct gaaaagattg ccaaagaaaa cctggaaaag
     4021 gtcggcatgg gagaacgcta ctggcaagcc aaaccaaaac aactctcagg tggtcaaaaa
     4081 caacgtgtgg ccatcgctcg tgccctctcc atgaatccgg acgctattct ctttgatgaa
     4141 ccaacatcag ctctcgatcc agaaatggtt ggagaagtcc tcaaaatcat gcaggacctg
     4201 gctcaggaag gcttgaccat gattgtcgta acccatgaaa tggaatttgc ccgtgatatc
     4261 tctcaccgtg ttatctttat ggataagggc gtgatcgctg aagaaggtaa accagaagac
     4321 ctcttcacca atcctaaaga agaccgaaca aaagagttcc ttcaacgcta tctcaaataa
     4381 aaagaaaagg ctgcatcaac cgtgcagtct ttttgctgtc ctcaaaatga aaaggcagat
     4441 tctctatctc tactacttga aggtcaagaa tccgccgtta tccaaagatt aatcttcaaa
     4501 tttttcataa tttttttcat agaaatcaat taagcctagg gctgtttcaa atgaaatatt
     4561 ttttactttt gcacgaccct gcgccagagc aatgatagac atttcacgcg cattcgtttc
     4621 tttagagata cggtagcctg tgattttctt atcacgaacc cagccaacaa ctgattctac
     4681 tttttcaaag tttgacttag ccatgttttt ctcctatttt cttctttata atatttaatt
     4741 gtatacgttt ttgctacttt tgtcaataaa aaaacatata ttcaacgaaa ataattagtt
     4801 cagaattttc ttacttcctt tttaaatccg ataatatata taggttttgc tagcctctac
     4861 accataaata tttgctaata aaaatgctgt attattaccc tcttaaggtg caaaattatt
     4921 caagttctta aaaaatgctt ctctatttcc gtaagatagc ttatttcttc gatttaagaa
     4981 ttgaagatga tagttctaac ctttagaaat ccaagccttc actagctcaa aaactcctat
     5041 ctttcttcct caataaatca tctgagagat aggtattcct tatgtccttc aaattcatca
     5101 ctcctttgga tattgaggtg ctagcctaga agcagacacc cgattatcta aaccatcctt
     5161 aataaagatg acaagacaga taagctcagt taattactta tatatctttt taatatggta
     5221 tatttgtcaa caaaaagaaa tcaaatcata ccttatactc aatgaaaatc aaagagcaaa
     5281 ctaggaagct agccgcaagt tgctcaaaac actgttttga ggttgcagat agagctaacg
     5341 tggtttgaag agattttcga agagtattaa agacagtgtg actatgcttg tcaatagata
     5401 ggaaatcaaa atgaaggatg gaaatctgag ccaaacatca taagtgctat aatgaacaga
     5461 agtaagaatt gcacgataag ttttctaaaa ccataggaat cgtccccttt cttcatcttc
     5521 attatagcac atatacatca gttgtacaaa taatatgata tttttttatt agtcctcaga
     5581 caagcatatt ataaagcgtt tcattaccat ttaagttaat ataagctgga tcaaaacctt
     5641 ccattctacg gatcaaacct gcataatcat gcttatctgc caaagcgatc ccaatcaata
     5701 ctgggcctgt tcccttgcta gctcgtttga tatactcaaa acgtgtgata tcatcatttg
     5761 gccccaggat atcatttaca aactcacgca aagctcctgg acgctgtggg aaattgacca
     5821 caaagtaatg tttgatacca tcataaatca aggcacgctc ttccatttct ggcatacggt
     5881 tgatatcatt atttcctcca gaaatgatac aacaaatggt tttcccctta atatattcag
     5941 ctaaaacctc taaagaggcg atactagccg ctccagcagg ctctgcgact atcccttgct
     6001 tagagtaaag gtcaatcaag gtttcagaaa tcaatccctc atcgacacct accaaagttt
     6061 gaatatgttg acgagttgct tcataggtca actgacctac cttttgcaca gcaatcccat
     6121 ccgcaaattt atcaatttcc ttgagtttga ctggacctcc agcctcaaag gcagctttca
     6181 tggaacgcgc tccattcgcc tctactccga taacctcaat ctctggactt gtttccttga
     6241 tataggtaga aaccccggca atgagaccgc caccaccaac aggaaccaag acagcatcaa
     6301 aatcaatcga ttcttttcga gcttcttcta aaatctcata agcaactgtt ccttgacctg
     6361 cttgaacatg agcatcatca aaaggatcaa taaaggtacg attttcagag actgtaaatt
     6421 cttgagctgc tttggctgag gcatcaaagg tatctccaac tagtttaata gttacaaaat
     6481 ccccaccaaa aaagcgaacc tgaccaatct tttgttgtgg cgtagtaata ggcataaaga
     6541 tagtagcagg aattttcatt tcattacaag tataggctac tccctgcgca tgatttcccg
     6601 cagaagcgca gactacccca cgttcacgtt cttccttgct gagctgggaa atggcataat
     6661 aggcaccacg aattttaaag gagcgaacac gctgggcatt ttcttttttc aaataaatct
     6721 tagcaccata cttctccgat aaataatgat cgtaatccag tggagtattc acaaccacac
     6781 cgttcaagac cttgtgagcc ttgattatat cttttgaact taacatataa aacctctttt
     6841 tctataaaaa acagtcacta atgactgttt tttagttatt catctccgaa aacttcagta
     6901 acactttcat ggtatttatg agccatacga atcgaaaact ctttaggaag ttcataacga
     6961 tttgtggaaa tccaatcata taaccattct accaaacttt cttcactatc attacgatgg
     7021 aagataaaat agtttaaaat ttctttatat tctacatcat tcaaatccaa cgtgtctaca
     7081 aattgactac gaggaacaaa attagaatct aattttctta gttgatctgt caattctccc
     7141 aattgtaaat ccaactgaaa aaatagtttt tgcagttgcc tatcagtttc atcacatcct
     7201 gtcttgatag aaaacaaatt ggtaatattc atatgatttc aacccctaaa taagtacatc
     7261 taatatccca cgaatagctg aagctaaagt tttcgcagtc cagtcattta aacccgattc
     7321 tttcaatcca gatgcaataa tttgctctat ttgatataaa ccgccatcta tcgtctcatt
     7381 tattctgcga agaggacctt caatatagga taaagcttct ccgaatctaa cagctgattt
     7441 aggtcctaat gatttaccaa ctatatttgt taatgttttt tatttctcaa aatccatttc
     7501 gctatataac gagcagattt agtcgcacca gctctctcaa acggagaatg aatttcaaga
     7561 ccttcttctc tagctatttg tgccaatttg aagaattgtt caaaggtcat atgcaaccta
     7621 ccatcttcaa aattagcatc atcataaatg ttaattacag cattttcatc atacgaccaa
     7681 tctgctttat tttggtctgc tagcactatt accgacggtg taattacatt atacaactag
     7741 aaccaataat aacgatgcag tttttctcat aatctttttc ataaaatcat ctccagcgct
     7801 atatatttct aattagttat agattttgaa tgcatcatcg tcgtttttac caacgaatgg
     7861 cattgcttta cgcaattctg caccaacttt ttcaatttca aggttagctg cttgttcacg
     7921 gtaagcagtc aattttggac gtccagcttt atagtcattt acaaagtcat ttgcaaattt
     7981 accattttgg atgtctgcca agacagcctt catattttct ttaacttgtt cagtgattac
     8041 acgtggacct gatacatagt caccgtattc agcagtgttt gaaatagatt gacgcatttt
     8101 cttgaatcca ccttcgtaga tcaagtcaac gatcaatttc atttcgtgaa gaacttcaaa
     8161 gtaagccaat tctggagcgt aacctgcttc tgtcaagact tcgaaacctg cttcgataag
     8221 ggcagtcaaa ccaccacaaa gtacagcttg ttcaccaaac aaatcttctt cagtttcttc
     8281 tttgtaagtt gtttcaagaa gacctacacg agccgctcca acacctttac accagtccat
     8341 agcaatgttt ttagcatttc ctgttgcatc ttggtatact gcataaagag ctggaacacc
     8401 aaatccttct tcgtaagtac gacgtaccaa gtgtcctggt cctttaggag cacacatgaa
     8461 gacatctaca tccgcaggaa ctttgataaa ttcaaagtgg atgttgaaac catgggcaaa
     8521 tccaactgcg tttccagctt ccaagcttgg agcgatttct gcttcgtaca attcttgttg
     8581 aatttcgtct ggcgccaaga tcatgataac atcagccaac ttagtagctt ctgctactgt
     8641 gtaagtatca aatccatctt cttttgcttt atcaaaagat ttacctggac gtacaccgat
     8701 aataacgtca cgacctgaat cacgcaagtt ttgagcatgc gcatgccctt gtgaaccata
     8761 accgataacg gcgatttttt taccgtcaag tgctgctact ttaacatctt tttcatattc
     8821 catttgaact gtcatagctt ttctctcttt tctattattt attgcctttt aggctggttt
     8881 aataaattta agttggattt ttaatcgcgg gtaaatccag ttgcacccgt tcgagcaata
     8941 ttgcgaatac cgtatgggcg aatgactcgc aatagggctt cgctcttttc tgcatttccc
     9001 gtcatctgaa tggtaatcga gctcggcgct acgtctacca ctgttgcacg gaaaggttga
     9061 ataatcgcta aaatctcagc tctcttctca gctggcgctg acatcttaac caaaatcacc
     9121 tcgcgctcca aatgaggctt gtctgtaata tctcgaatgc gaatcacatc aatctgacga
     9181 ttgagctgtt tgatgatttg ctccacttca tcatgagaag caacatcaat aataatagtg
     9241 atacgcgata cattcggatc ttctgttgct ccaacagaga tgctttcaat attaacctga
     9301 cgacgagata ggacacctgt aaagcgattg aggactcctg aacgattttg tagttttgct
     9361 gttaacattc tacgcatgga actgcacccc caacatctca tgattactct taccagccgg
     9421 taccattggt aacacctgtt ccttacgaga aatatctacc tcaattagca taggaacatc
     9481 ctcagtgatg acttcaaggt cttgagccaa ggtctcagga ttgtcaaact tatagttttt
     9541 aataccataa gcctgcgcca tcaattggaa atcaggaagg gtatcaaaga ccgactctga
     9601 tgttctgcct tcatagaagg attcctgcca ctggcgaacc attccgagtg aatgattgtt
     9661 cagcataacc accttgattg gcaccttgta aatattcaaa atagccaact cctggttggt
     9721 catttggaaa ccaccatccc caacaaacaa gactacttcc ttatctgggt tagcaatttt
     9781 agcaccgatt gctgctggaa ttccaaagcc cattgttccc aaaccacctg aagtcactaa
     9841 ctgacgttca ttttggtagg gataatactg agctgtccac atttggtgtt gaccaacgtc
     9901 tgttaccaca atggcatctc cattcgtcaa ttcaccaatt cgttcaataa ctgcttgcgg
     9961 ttgaaccaca cgctctttct tgtcataaga acgaacacga ttcttgtctt tagtgacttt
    10021 ctcaatccac ttttcagtat tgttgtgaac tgttggttct gctagcaaca tttgcaaggc
    10081 cttcttagca tctccaacta caggaatgtc tgcactgata atcttgccaa tctcagctgg
    10141 gtcaatatca atgtgggcaa ccttagcatt cttagcgaaa gtcttaggat tccccgtcaa
    10201 acggtcatcg aaacgagaac caatactaat cataaagtcc gcttccgtca tggcaatatt
    10261 tgctgcgaat gacccgtgca tgcctcccat tccaagaaag agtgggtgac tcgttgcaat
    10321 cgttccttgt cccaaaagac tggttaccac tggaatttga tagcgttctg caaattcatt
    10381 tagttccgta gcagcctcag cataactaat tccaccacca gctaacaaga ctggcttttt
    10441 agccttggac aattgcttca agatcttctt gatttgcata tcattcggct caagagtcgg
    10501 ctgataactt ggtaaattca cttctggtga ataaatgaag tctgtttcta aagcagatat
    10561 gtcttttggt aggtcaatta caactggccc tggacggcct gtagttgcga tatggacagc
    10621 ttccgtaatg atacgcggaa tatcagctgt ctcacgaact tggtaattgt acttagtgat
    10681 tggcatggta attcccacga tgtctgcctc ctgaaaggca tccttcccaa tccctgctcg
    10741 cgccacctga cctgtaaaga ccaaaagggg aacgctatcg ctcatggcat ccgcaatccc
    10801 tgtaatggca tttgttgctc ctggtccact agtgacgacg gcaacaccca actttccagt
    10861 tgatttggca taaccttcag cttcatgcaa acaaccttgc tcatggcgcc ctagaatgtg
    10921 gcgaatgcct ttaaaattat atatcgcatc ataaaaaggc aaaaccgcac caccaggata
    10981 accaaagatg gtatcaactc ctaaatcacg aagtgtttcc aaaactaggt ccgaccccgt
    11041 cttaggagat tctaaactga ttttctccat tgttcccctt tctttcctct taaaaataac
    11101 ttgttactat cataccattt tttcaaaatt tttcaagata aaagaagaaa ttttctgaat
    11161 tttctatttt aacgtttatt tatgaatgtt atttttgttt ttattaaaaa gataccgttt
    11221 tcatttacta aaaaagaaaa aagaactgat ttctcagtcc t
//
LOCUS       DAVHBD010000052        10859 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000052 DAVHBD010000000
VERSION     DAVHBD010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10859
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.052"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            95..1297
                     /gene="pspC"
                     /locus_tag="VVK04_001813"
     CDS             95..1297
                     /gene="pspC"
                     /locus_tag="VVK04_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HEU3990440.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATEKEGST
                     QAATSFNRGNGSQAEQRGELDLERDKAMKAVSEYVGKMVRDAYVKSDRKRHKNTVALV
                     NQLGNIKNRYLNEIVHSTSKSQLQELMMKSQSEVDEAVSKFEKDSFSSSSSGSSTKPE
                     TPQPENPEHQKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQ
                     KHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFK
                     KGLTQDTPKEPGNKKPSAPKPGMQPSPQPEVKPQLEKPKPEVKPQPEKPKPDNSKPQA
                     DDKKPSTTNNLSKDKQPSNQASTNEKATNKPKKSLPSTGSISNLALEIAGLLTLAGAT
                     ILAKKRMK"
     gene            complement(1516..2496)
                     /gene="dusB"
                     /locus_tag="VVK04_001814"
     CDS             complement(1516..2496)
                     /gene="dusB"
                     /locus_tag="VVK04_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU3990441.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKV"
     gene            complement(2483..3355)
                     /gene="hslO"
                     /locus_tag="VVK04_001815"
     CDS             complement(2483..3355)
                     /gene="hslO"
                     /locus_tag="VVK04_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU3990442.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            3520..4947
                     /locus_tag="VVK04_001816"
     CDS             3520..4947
                     /locus_tag="VVK04_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU3990443.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            5106..6614
                     /gene="glpK"
                     /locus_tag="VVK04_001817"
     CDS             5106..6614
                     /gene="glpK"
                     /locus_tag="VVK04_001817"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU3990444.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            6656..8482
                     /gene="glpO"
                     /locus_tag="VVK04_001818"
     CDS             6656..8482
                     /gene="glpO"
                     /locus_tag="VVK04_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU3990445.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKRTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDNKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            8552..9256
                     /locus_tag="VVK04_001819"
     CDS             8552..9256
                     /locus_tag="VVK04_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU3990446.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVFVFSLF"
     gene            9553..9756
                     /locus_tag="VVK04_001820"
     CDS             9553..9756
                     /locus_tag="VVK04_001820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990447.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(9843..10430)
                     /locus_tag="VVK04_001821"
     CDS             complement(9843..10430)
                     /locus_tag="VVK04_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990448.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         3284 a         2129 c         2407 g         3039 t
ORIGIN      
        1 aaatattata gagccaaata atgtagcaaa tttcatatac aattcatatt agcaggatat
       61 actgtagtta attaaaatta tggagaatat agacatgttt aaatcaaatc atgagcgaag
      121 aatgcgttat tccattcgta aatttagtgt aggagtagct agcgtagctg ttgccagtct
      181 ttttatggga agtgttgtac atgcgacaga gaaagaggga agtacccaag cagccacttc
      241 ttttaatagg ggaaatggaa gtcaggcaga acaacgtgga gaactcgatt tagaacgaga
      301 taaggcaatg aaagcggtca gtgaatatgt aggaaaaatg gtgagagatg cctatgtaaa
      361 atcagataga aaacgacata aaaatactgt agctctagtt aaccagttgg gaaacattaa
      421 gaacaggtat ttgaatgaaa tagttcattc aacctcaaaa agccaactac aggaactgat
      481 gatgaagagt caatcagaag tagatgaagc tgtgtctaaa tttgaaaagg actcattttc
      541 ttcgtcaagt tcaggatcct ccactaaacc agaaactccg cagccggaaa atccagagca
      601 tcaaaaacca acaactccag ctccggatac caaaccaagc cctcaaccag aaggcaagaa
      661 accaagcgta ccagacatta atcaggaaaa agaaaaagct aagcttgctg tagcaaccta
      721 catgagcaag attttagatg atatacaaaa acatcatctg cagaaagaaa aacatcgtca
      781 gattgttgct cttattaagg agcttgatga gcttaaaaag caagctcttt ctgaaattga
      841 taatgtaaat accaaagtag aaattgaaaa tacagtccac aagatatttg cagacatgga
      901 tgcagttgtg actaaattca aaaaaggctt aactcaggac acaccaaaag aaccaggtaa
      961 caaaaaacca tctgctccaa aaccaggtat gcaaccaagt cctcaaccag aggttaaacc
     1021 gcagctagaa aaaccaaaac cagaggttaa accgcagccg gaaaaaccaa aaccagataa
     1081 tagcaagcca caagcagatg ataagaagcc atcaactaca aataatttaa gcaaggacaa
     1141 gcaaccttct aaccaagctt caacaaacga aaaagcaaca aataaaccga agaagtcatt
     1201 gccatcaact ggatctattt caaatctagc acttgaaatt gcaggtcttc ttaccttggc
     1261 gggggcaacc attcttgcta agaaaagaat gaaatagtga ttgattcatt caaaaatgtt
     1321 tgtaaaaagt attcgactta aaagaaaaga gtctgggata aaaagatttt gattttagga
     1381 attctttatt ataaattttt aaaatcgata gattagacaa aaaagcgaac aagacagaat
     1441 tctgagtgtc agataactga ttttgttcgc tttttatatt taatattata cttttgtcct
     1501 aggctctttt ttgcattata ctttttccaa ttgcaagaga gcttcaatct ctgctagggt
     1561 gctagcttgc gaaatggctc cacggagttt ggcagcgcca gatgttccac ggagatagtg
     1621 aggagcgagg ccgcggaatt cacgaactgc gacgttttct cctttgaggt taatcaatcg
     1681 tttcaagtgt tcgtaggcga tcttcatctt gtcttcaaat gtcaaatcag gtaggatttc
     1741 tcctgtttca aagtaatggt tgatttggtt gaagaggtaa ggatttccca tggcagctcg
     1801 gccaatcatg actgcgtcag caccaacttc ttcgatgcgt tgcttggctt cttggacagt
     1861 acggatatca ccgttggcga tgaatggaat cttggttaga gcttgggcaa ccttgtaaag
     1921 ggtctcaagg tccgcgtggc cagtatacat ttgttcacgg gtacggccat gcatggcgag
     1981 ggcagaaaca cctgcagcct cagcagcgag ggcattttct actgcaagag atgggtccgc
     2041 ccagccggta cgcattttga cagtaagtgg gatatcaagg acagactgga ccttgttgat
     2101 gatagagtag atcttgtcag gatccttgag ccacatagca ccagcttcgt tcttcacgat
     2161 tttgttgaca gggcagccca tgttgatatc gacgatatcg gtcttggtgt tttcttggat
     2221 gaattctgct gcgcgtgcta ggctgtcttc atcgctacca aaaagttgga tagagacagg
     2281 gttttcgccc tcatcgatat gaagcatgtg cagggttttt tcgttgttgt attggattcc
     2341 cttgtcagag accatttcca ttacaacgag tccagctccg agctcttttg ctatggtacg
     2401 aaaggctgag ttggtcacgc cagccatagg cgctaaaacg gtacgattgg gaatctcaat
     2461 attgccaatc ataaaaggtg tattaagatt tgtcacgaat gagttcctcc aggtcctttt
     2521 catcaaagtt gtaagtagtt tggcagaatt gacaagtgat ttctgcaccg tggtcttcct
     2581 ctttcatttc ctgtaagtct gagcttggaa ggctggcaag agcgttcata aagcgttcat
     2641 ggctacagtc acattggaaa cggatttctt cttcagaaag acgcttgtag gcttcgtccc
     2701 cgtagatagc cttgaggagg gcttcgatat ggtcgtcgct ttcgagaaga gtagagatag
     2761 ctggcatttc ttggatgcgt ttttcaaagc gagcaatctc ttctttcttg gctcctggca
     2821 agacttgaac taggaaacca cctgcaacct tgaccttgtc ttcctcgtcc aaaaggacat
     2881 tgaggccgac cgctgaaggc gtttgttggc tttcagtaag gtaaaaggca aggtcttcac
     2941 cgatttctcc agagatgagg ggagttatag agttgtaagg atttccagta ccgtagtctg
     3001 tgataacgag gaattgacca tttccaacaa aaggtccgac taggacttca ccagtcgcag
     3061 tctttttgat gtcaacacca ggattttgaa catagccttt gacgttcccc ttggtatcag
     3121 cgacggtgat aatagcacct agagagctag atcccaacac cttaactgta agtttggtat
     3181 ttcctttttc attggctgcg agaatctggc tagcgataag agttcgacca agcgctacag
     3241 ttgagctagc ttgggtttga tgtttttctt gagcagtgcg gacggtttca gtgctatcaa
     3301 ggacaaaagc acgaaaggct ccgctttctg atatagtttt aataatttta tccatagcta
     3361 ctattttagc ataaaaatgc ccaaaggggg agccgtgtgt ttactgattt tcaggataat
     3421 ggaccaggaa atcagcatga aaataaaaag agaaacagat tattttagca tttgtcagat
     3481 ttatgctatg cttaaggtag aaaatgaaag gggtaacaaa tgtatttagg agatttgatg
     3541 gagaaagccg agtgtggtca attttcaatc ctttcctttc tattacaaga gtctcagacg
     3601 accgtcaagg ctgtaatgga agaaacagga ttttcaaaag caaccctaac caaatatgtc
     3661 accctgctca atgacaaggc tttggatagt ggcttagagc tgactattca ctcagaagat
     3721 gaaaatctgc gtctgtctat cggtgcagct accaagggga gagatattcg gagcttgttt
     3781 ttggagagtg ctgttaaata ccagattttg gtttatcttc tctaccacca acagttttta
     3841 gcccatcagc tggctcaaga attggtgatt agcgaggcta cgcttggtcg tcacttggct
     3901 ggtttaaatc agattttgtc agaatttgat ttatccatcc aaaatggacg ttggcgaggt
     3961 ccagagcatc agattcgcta tttctatttc tgtcttttcc gaaaggtctg gtcgagtcag
     4021 gaatgggaag gtcacatgca gaaaccagag agaaaacagg agattgccaa tttagaggaa
     4081 atctgcggtg caagtttgtc tgcggggcag aaattggact tggttctctg ggctcacatc
     4141 agtcaacaac gtcttcgggt caatgcttgt cagtttcaag tcatagaaga gaaaatgcga
     4201 gggtattttg acaatatctt ttatcttcgt ttgctgagaa aggttccgtc cttttttgct
     4261 gggcaacata ttccactagg agttgaggat ggtgagatga tgatattctt ctcttttctc
     4321 ctatctcatc gcattcttcc tcttcatact atggagtata ttcttggttt tggagggcag
     4381 ttggcagatt tactgacgca attgattcaa gaaatgaaga aggaggaact attgggggat
     4441 tatacagagg accatgtcac ctatgaactc agtcagcttt gtgctcaagt ctatctctat
     4501 aagggctata ttttacagga tcgctacaag taccagttag agaatcgtca tccatattta
     4561 ctgatggaac atgattttaa agagacagca gaggagattt ttcatgctct gcctgctttt
     4621 caacagggga cagatttaga taagaagatt ctctgggaat ggctccagtt aatcgaatat
     4681 atggctgaaa acggtggcca gcatatgcgg attggtctgg atttgacatc tggttttctt
     4741 gtcttttcaa ggatggcagc cattttgaaa cggtatttgg aatacaatcg ttttattacc
     4801 attgaagctt atgaccctag tcggcattat gatttgctgg ttaccaataa cccgattcat
     4861 aagaaggaac agacaccagt ctattattta aaaaacgact tggatatgga agatttggca
     4921 gggattcgtc agttattatt cacttaaaag gcttggttaa tccaggtctt ttttgtgaaa
     4981 ttcacacaat ctcctcacat ttttttaaaa attaaaaaaa gttgataaac aagaaagcgc
     5041 tttattttgt atactagtaa gtgtaaagag gaaacacctc aagatcttta tcaggaggac
     5101 agtatatgtc acaagaaaaa tacatcatgg ccattgacca gggaactaca agttctcgtg
     5161 ccatcatttt caacaaaaaa ggggaaaagg ttagctcgag tcaaaaagag tttacccaga
     5221 ttttccctca ggcaggttgg gttgagcaca atgccaatga aatttggaac tctgttcagt
     5281 cagttattgc gggtgctttc atcgaaagtg gtgtcaagcc aaatcaaatc gaggcaatcg
     5341 ggattaccaa ccaacgtgaa acaacggttg tctgggataa gaaaacagga cttcctatct
     5401 acaatgctat cgtttggcag tcacgccaga cagcaccttt ggctgagcaa ctaaaaagcc
     5461 aaggttatgt ggaaaaattc catgaaaaga ctggtttgat tattgatgct tacttctctg
     5521 ctaccaaggt tcgttggatt ttggatcatg tagaaggtgc tcaagagcga gcagaaaaag
     5581 gggaattgct ctttggtact atcgatactt ggttggtttg gaaattgact gacggtgcgg
     5641 ctcacgtgac tgactactca aatgcagctc gtaccatgct ttataacatt aaagaactca
     5701 aatgggatga tgagattttg gaaatcctta acattccgaa ggctatactt ccagaagttc
     5761 gttctaactc cgaaatctac ggcaagacag ctccattcca tttctacggt ggagaggtgc
     5821 caatctcagg tatggctggg gaccaacaag cagccctctt tggacagttg gcttttgagc
     5881 caggtatggt taagaatact tatggaacag gctctttcat catcatgaat actggggaag
     5941 agatgcagtt gtctgaaaac aacctcttga caaccattgg ttacggaatc aacggtaagg
     6001 tttattatgc cttggaaggt tctatcttca tcgcaggaag tgctattcag tggcttcgtg
     6061 acggtcttcg catggttgaa aattcaccag aatctgaaaa atacgctcgt gattctcaca
     6121 acaacgatga agtttatgtc gttccagcct ttacaggtct aggcgctcca tactggaacc
     6181 aaaatgctcg tggttccgtc tttggtttga ctcgtggaac aagcaaagaa gactttatca
     6241 aggcgacttt gcaatctatt gcttatcaag tgcgtgatat catcgacacc atgcaagtgg
     6301 atactcagac cgccattcaa gtactgaagg tggatggtgg tgcagccatg aacaacttcc
     6361 tcatgcagtt ccaggcggat attttaggca ttgacattgc acgtgctaaa aacctggaaa
     6421 caacagctct aggagcggcc ttcctagcag gtttgtcagt agggtactgg aaagacttgg
     6481 acgagttgaa actcttgaac gagacaggag aactctttga gccatctatg aacgaatctc
     6541 gcaaggaaca actctacaag ggctggaaga aggctgtgaa agcaactcaa gtctttgcgg
     6601 aagtagacga ctaatactgg cagaataaag cgatttattt agaaagtgtg taaatatgga
     6661 attttcaaag aaaacacgtg aattgtcaat taaaaaaatg caggaacgca ccctggacct
     6721 cttgattatc ggtggaggaa tcacaggagc tggtgtagcc ttgcaggcgg cagctagcgg
     6781 tcttgagact ggtttgattg aaatgcaaga ctttgcagaa ggaacatcta gtcgttcaac
     6841 aaaattggtt cacggaggtc ttcgctacct caaacaattc gacgtagaag tggtctcaga
     6901 tacggtttct gaacgtgcag tggttcaaca aatcgctcca cacattccaa aaccagatcc
     6961 aatgctctta ccagtttacg atgaagatgg agcaaccttt agcctcttcc gtcttaaagt
     7021 agccatggac ttgtacgacc tcttggcagg tgttagcaac acaccaactg cgaacaaggt
     7081 tttgagcaag gatcaagtct tggaacgcca gccaaacttg aagaaggaag gcttggtagg
     7141 aggtggagtg tatcttgact tccgtaacaa cgatgcgcgt ctcgtgattg aaaacatcaa
     7201 acgtgccaac caagacggtg ccctcattgc caaccacgtg aaggcagaag gcttcctctt
     7261 tgacgaaagt ggcaagatta caggtgttgt agctcgtgat ctcttgacag accaagtatt
     7321 tgaaatcaag gcccgtctgg ttattaatac aacaggtcct tggagtgata aagtacgtaa
     7381 tttgtctaat aagagaacgc aattctcaca aatgcgccca actaagggag ttcacttggt
     7441 agtggattca agcaaaatca aggtttcaca gccagtttac tttgacacag gtttgggtga
     7501 cggtcgtatg gtctttgttc tcccacgtga aaacaagact tactttggta caactgatac
     7561 agactacaca ggtgatttgg agcatccaaa agtaactcaa gaagatgtag attatctact
     7621 tggcattgtc aataaccgct ttccagaatc caacatcacc attgatgata tcgaaagcag
     7681 ctgggcaggt cttcgtccat tgattgcagg gaacagtgcc tctgactata atggtggaaa
     7741 taacggtacc atcagtgatg aaagctttga caacttgatt gcgactgttg aatcttatct
     7801 ctccaaagaa aaaacacgtg aagatgttga gtctgctgtc agcaagcttg aaagtagcac
     7861 atctgagaaa tatttggatc catctgcagt ttctcgtggg tctagcttgg accgtgatga
     7921 caatggtctt ttgactcttg ctggcggtaa aatcacagac taccgtaaga tggctgaagg
     7981 agctatggag cgcgtggttg acatcctcaa agcagaattt gaccgtagct ttaaattgat
     8041 caattctaaa acttaccctg tttcaggtgg agaattgaac ccagcaaatg tggattcaga
     8101 aatcgaagcc tttgcgcaac ttggagtatc acgtggtttg gataacaagg aagctcacta
     8161 tctggcaaat ctttacggtt caaatgcacc gaaagtcttt gcacttgctc acagcttgga
     8221 acaagcgcca ggactcagct tggcagatac tttgtccctt cactatgcaa tgcgcaacga
     8281 gttggctctt agcccagttg acttccttct tcgtcgtacc aaccatatgc tctttatgcg
     8341 tgatagcttg gatagcatcg ttgagccagt tttggatgaa atgggacgat tctatgactg
     8401 gacagaagaa gaaaaagcaa cttaccgtgc tgatgtcgaa gcagctctcg ctaacaacga
     8461 tttagcagaa ttaaaaaatt aagaaaaaat aaaagaggtg gagggcagca ttccttgtcg
     8521 cccgtccctt ctttttaatg gagacagaaa gatgatgaat gaattatttg gagaatttct
     8581 agggacttta atcctgattc ttctaggaaa tggtgttgtt gcaggtgtgg ttcttcctaa
     8641 aaccaagagc aatagctcag gttggattgt gattactatg ggttggggga ttgcagttgc
     8701 ggttgcagtc tttgtatctg gcaagctcag tccagctcat ttaaacccag ctgtgaccat
     8761 cggtgtggcc ttaaaaggtg gtttgccttg ggcttccgtt ttgccttata tcttagccca
     8821 gttcgcaggg gccatgctgg gtcagatttt ggtttggttg caattcaaac ctcactatga
     8881 ggcagaagaa aatgcaggca atatcctggc aaccttcagt actggaccag ccatcaagga
     8941 tactgtatca aacttgatta gcgaaatcct tggaaccttt gttttggtgt tgacaatctt
     9001 tgctttgggt ctttacgatt ttcaggcagg tatcggaacc tttgcagtgg gaactttgat
     9061 tgtcggtata ggtctatcac taggtgggac aacaggttat gccttgaacc cagctcgtga
     9121 ccttggacct cgtatcatgc acagcatctt gccaattcca aacaagggag acggagactg
     9181 gtcttacgct tggattcctg ttgtaggccc tgttatcgga gcagccttgg cagtgtttgt
     9241 attctcactt ttctagttta tactcttcga aaatcaaatt caaaccacgt cagcgtcgcc
     9301 ttaccgtact caagtacagc ttgcggctag cttcctagtt tgctctttga ttttcattga
     9361 gtattagaaa acaattatgt tgatagagct tgggcaagag cccaatttca gcaaaaaatg
     9421 aagtaaatct tctcataata aaacgcatca tatcaagcac gaaaattcca cgaggtcaac
     9481 tacagtcaga aagctgaaca acaagccaaa acgcccaaaa aaggcggcaa aaagcaagca
     9541 cctgcaagca acgtgccgaa atggtcaaat cctgattatg tcaacgaatt agacccaaaa
     9601 atcgttgata tgctagtaga atttcacaag tcacaaggca ctttggaaac tcccgaggcg
     9661 caagcagaaa tcgcccaaaa acgtgaagaa atcgagcaaa ggagagctga gcttgagggt
     9721 aaaaaacaag agcttttgaa ccgcttgaac aaatagagtt tcgcaagtat tatgcttaca
     9781 aattacttga gcaattaact aaaatataaa ccctgccttt atatctaggc agggtttata
     9841 ttttagaaat tcacgtaggt tgttacggtt tttacatacc cagtatagtt tgagtttcta
     9901 tagtattcag tgataaactt ccattttctt tgagcaacat ggatataagt acttgttatg
     9961 tagtatggat atgggctttg tgaatccaag taagactgat aagcttgtat accaaaatat
    10021 gctccaccaa ttattgcacc ccatggaccc cccaataaag cacctatcct accaatcata
    10081 taactgattc cagcaccagt catgaagtta gcgaatgtgt tagcttgttt attcccatgt
    10141 attgtgttga cgtaattcca aacattagga tcgtatgatc taaaagatat atttaggtcg
    10201 atttcattct tttgataagc catataaaat gccccattga tatagacgcc gtcagcacgt
    10261 cgttcaatag tgtctacact tccatctgga ttgacaacct caagaacttc atcgcttaaa
    10321 atatttactt gcgtatctcc gaaccgcact gatgagccat tctcaaactg agcctcacca
    10381 gatacaactt tagagtttgc cgataagcta tcatcagcaa aaacaaacaa gcgacgggga
    10441 aatgctagac atacagaaaa cagacataac tagcaaacac atgcatttaa acatcttaga
    10501 cataacggaa actcctttgt atttttgatt tttttcaact tttattatac aataaaacca
    10561 aataaaaaga aagcggtaac aatatgctta atgcgaaaat tttttatata tttttatgtt
    10621 tgatcgttat cgaaactaca ggcttgttgt tgttgaaaag aggtctcgaa atgggttatt
    10681 tagacacaga agctattatc ctcgcagttt tttcatttgc tttttacaac ctatgttcat
    10741 tcgcttgggt ctgctctaca ataaaaaaca ataaaaaata aatagacgta ttttcaaaaa
    10801 aaaaaaaaaa atgcatattt atcttagcaa aacgacgatt taaatcgtcg tttttttgt
//
LOCUS       DAVHBD010000053         9825 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000053 DAVHBD010000000
VERSION     DAVHBD010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9825
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.053"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            88..1026
                     /gene="msrB"
                     /locus_tag="VVK04_001822"
     CDS             88..1026
                     /gene="msrB"
                     /locus_tag="VVK04_001822"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU3990449.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1084..2808
                     /locus_tag="VVK04_001823"
     CDS             1084..2808
                     /locus_tag="VVK04_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990450.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2810..4561
                     /locus_tag="VVK04_001824"
     CDS             2810..4561
                     /locus_tag="VVK04_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990451.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            4908..6167
                     /locus_tag="VVK04_001825"
     CDS             4908..6167
                     /locus_tag="VVK04_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU3990452.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6243..6378
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6417..6917
                     /locus_tag="VVK04_001826"
     CDS             6417..6917
                     /locus_tag="VVK04_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU3990453.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6993..7361
                     /gene="rplL"
                     /locus_tag="VVK04_001827"
     CDS             6993..7361
                     /gene="rplL"
                     /locus_tag="VVK04_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU3990454.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7548..7718
                     /locus_tag="VVK04_001828"
     CDS             7548..7718
                     /locus_tag="VVK04_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990455.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            7718..7966
                     /locus_tag="VVK04_001829"
                     /pseudo
     CDS             7718..7966
                     /locus_tag="VVK04_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            7980..8320
                     /locus_tag="VVK04_001830"
                     /pseudo
     CDS             7980..8320
                     /locus_tag="VVK04_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8313..8693
                     /locus_tag="VVK04_001831"
     CDS             8313..8693
                     /locus_tag="VVK04_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU3990456.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            8706..8849
                     /locus_tag="VVK04_001832"
     CDS             8706..8849
                     /locus_tag="VVK04_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990457.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            8942..9529
                     /locus_tag="VVK04_001833"
     CDS             8942..9529
                     /locus_tag="VVK04_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3990458.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            9731..>9825
                     /locus_tag="VVK04_001834"
     CDS             9731..>9825
                     /locus_tag="VVK04_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU3990459.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFST"
BASE COUNT         2924 a         1841 c         2125 g         2935 t
ORIGIN      
        1 aacatatata cggtaaggtg acgctgacgt ggtttgaaga gattttcgaa gagtattagt
       61 taaaaacgtg ataaaggaga aataaaaatg gcagaaattt atctagcagg tggttgtttt
      121 tggggcctag aggaatattt ttcacgcatt tctggagtgc tagaaaccag tgttggctac
      181 gctaatggtc aagtcgaaac gaccaattac cagttgctca aggaaacaga ccatgcagaa
      241 acggtccaag tgatttacga tgagaaggaa gtgtcactca gagagatttt actttattat
      301 ttccgagtta tcgatcctct atctatcaat caacaaggga atgaccgtgg tcgccaatat
      361 cgaactggga tttattatca ggatgaagca gatttgccag ctatctacac agtggtgcag
      421 gagcaggaac gcatgctggg tcgaaagatt gcagtagaag tggagcaatt acgccactac
      481 attctggctg aagactacca ccaagactat ctcaggaaga atccttcagg ttactgtcat
      541 atcgatgtga ccgatgctga taagccattg attgatgcag caaactatga aaagcctagt
      601 caagaggtgt tgaaggccag tctatctgaa gagtcttatc gtgtcacaca agaagctgct
      661 acagaggctc catttaccaa tgcctatgac caaacctttg aagaggggat ttatgtagat
      721 attacgacag gtgagccact cttttttgcc aaggataagt ttgcttcagg ttgtggttgg
      781 ccaagtttta gccgtccgat ttccaaagag ttgattcatt attacaagga tctgagccat
      841 ggaatggagc gaattgaagt tcgttctcgt tcaggcagtg ctcacttggg tcatgttttc
      901 acagatggac cgcgggagtt aggcggcctc cgttactgta tcaattctgc ttctttacgc
      961 tttgtggcca aggatgagat ggaaaaagca ggatatggct atctattgcc ttacttaaac
     1021 aaataaaaca gagagtgggg cttcccactt tcttcatttc tagaatatga atagaaggga
     1081 tttatgaaac acctattatc ttacttcaaa ccctacatca aggaatcaat tttagccccc
     1141 ttgttcaagc tgttagaagc tgtttttgag ctcttggttc ccatggtgat tgctgggatt
     1201 gttgaccaat ctttacctca gggagatcaa ggtcatctct ggatgcagat tggcctgctc
     1261 cttatctttg cagtaattgg cgttttagtg gccttgatag ctcaatttta ctcagcaaag
     1321 gcagcagtag gttttgctaa ggaattgaca aacgatcttt atcgtcatat tctttccttg
     1381 ccaaaggaca gcagagaccg tctgacaact tctagtttgg ttactcgctt gacttcggat
     1441 acctaccaga ttcagactgg tatcaatcaa ttcctgcgtc tctttttacg agcgcccatt
     1501 atcgtttttg gtgccatttt tatggcttat cgaatctcag ctgagttgac tttctggttc
     1561 ttagtcatgg ttgccatttt gaccattgtc attgtagggt tatctcgatt ggtcaatcct
     1621 ctctacagta gtctcagaaa gaaaacggac caactggttc aggaaacgcg ccagcaattg
     1681 caagggatgc gggttattcg tgcttttggt caagaaaaac gagagttaca gatttttcaa
     1741 acccttaacc aagtttatgc tagattacaa gaaaagacag gtttctggtc tagtttatta
     1801 acacctctga cctatctgat tgtcaatgga actcttctcg ttattatctg gcaaggctat
     1861 atttcaattc aaggaggagt gctcagtcaa ggtgctctca ttgctcttat caattacctc
     1921 ttacagattt tggtggaatt ggtcaagcta gccatgttga tcaattccct caaccagtcc
     1981 tatatctcag ccaagcgaat cgaggaagtc tttgttgagg ctccagagga tatccattca
     2041 gagttagaac aaaagcaagc taccagagat aaggttttac aagtccaaga attgaccttt
     2101 acctatcctg atgcggccca gccttctctg agagacattt cctttgatat gactcaagga
     2161 caaatccttg gtatcattgg ggggactggt tctggtaaat caagcttggt gcaactctta
     2221 cttggacttt atccagtaga caaggggaac attgaccttt atcaaaatgg acgtagtcct
     2281 cttaatttgg agcagtggcg gtcttggatt gcctatgtac ctcaaaaggt cgaactcttt
     2341 aaaggaacca ttcgttccaa cttgactcta ggtttcaatc aagaagtatc tgaccagaaa
     2401 ctctggcagg ccttggagat tgcgcaagct aaggattttg tcagtgaaaa ggaaggactc
     2461 ttggatgccc tagttgaggc aggggggcga aatttctcag gtggacaaaa acaaaggttg
     2521 tctatcgccc gagcagtctt gcgccaagct ccgtttctca tcctagatga tgcaacctcg
     2581 gcactggata ccattacaga gtccaagctc ttgaaagcta ttagagaaaa ttttccaaac
     2641 acgagcttaa ttttgatctc tcaacgaacc tcaactttac agatggcgga ccagattctc
     2701 ctcttggaaa aaggtgagtt gctagctgtt ggcaagcacg atgacttgat gaaatccagc
     2761 caagtctatc gtgaaatcaa tgcatcccaa catggaaagg aggactagaa tgaaacgaca
     2821 aactgtaaac cagacgctca aacgtttagc cgtagattta gcaaaccatc ccttcctcct
     2881 tttcctagct tttctaggaa ctattgccca agttggctta tcaatttacc tacctattct
     2941 gattgggcag gtcattgacc aagtcctagt ggctggttca tcaccagttt tttggcagat
     3001 ttttctccag atgctcttgg tggtaatagg aaatactctg gtacaatggg ccaatcctct
     3061 cctctataat cgtctaatct tctcttatac cagagattta cgagagcgaa tcatccataa
     3121 gctccatcgt ttaccgattg cctttgtaga taggcaaggt agtggagaga tggttagtcg
     3181 tgtaaccacg gacatcgaac agttggcagc tggcttgacc atgattttta accaattttt
     3241 cattggtgtt ttgatgattt tggtcagtat tctagccatg ctccaaattc atctcctcat
     3301 gactctctta gtcttgctgt tgacgccact gtccatggtg atttcacgct ttattgccaa
     3361 gaaatcctat catctcttcc agaagcaaac agagacgagg ggaattcaga ctcagttgat
     3421 tgaagaatcg cttagtcagc agactataat ccagtccttc aatgctcaaa cagaatttat
     3481 ccaaagattg cgtgaggctc atgacaacta ctcaggctat tctcagtcag ccatctttta
     3541 ttcttcaacg gtcaatcctt cgactcgctt tgtaaatgca ctcatttatg cccttttagc
     3601 tggagtagga gcttatcgta tcatgatggg ttcagccttg accgtcggtc gtttagtgac
     3661 ttttttgaac tatgttcagc aatacaccaa gccctttaac gatatttctt cagtgctagc
     3721 tgagttgcaa agtgctctgg cttgcgtaga gcgtatctat ggagtcttag atagccctga
     3781 agtggctgaa acaggtaagg aagtcttgac gaccagtgac caagttaagg gagctatttc
     3841 ctttaaacat gtctcttttg gctaccatcc tgaaaaaatt ttgattaagg acttgtctat
     3901 cgatattcca gctggtagta aggtagccat cgttggtccg acaggtgctg gaaaatcaac
     3961 tcttatcaat ctccttatgc gtttttatcc cattagctcg ggagatatct tgctggatgg
     4021 gcaatccatt tatgattata cacgagtatc attgagacag cagtttggta tggtgcttca
     4081 agaaacctgg ctcacacaag ggaccattca tgataatatt gcctttggca atcctgaagc
     4141 cagtcgagag caagtaattg ctgctgccaa agcagctaat gcagactttt tcatccaaca
     4201 gttgccacag ggatacgata ccaagttgga aaatgctgga gaatctctct ctgtcggcca
     4261 agctcagctc ttgaccatag cccgagtctt tctggctatt ccaaagattc ttatcttaga
     4321 cgaggcaact tcttccattg atacacggac agaagtgctg gtacaggatg cctttgcaaa
     4381 actcatgaag ggccgcacaa gtttcatcat tgctcaccgt ttgtcaacca ttcaggatgc
     4441 ggatttaatt cttgtcttag tagatggtga tattgttgaa tatggtaacc atcaagaact
     4501 catggataga aagggtaagt attaccaaat gcaaaaagct gcggctttta gttctgaata
     4561 agccattctc ttttgaaagt ttatggacga aaaaagttgc cttcgagtga cttttttgtt
     4621 acaatagcta gaaaaattgt tcactgtaat actcaatgaa aatcaaagag caaactagga
     4681 agctagccgt aggttgctca aagcacagct ttgaggttgt agataagact gacgaagtca
     4741 gttcaaaaca ctgttttgag gttgcagata gaactgacga agtcagctca aaacactgtt
     4801 ttgaggttac agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga
     4861 agtggtttga agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc
     4921 agcatgtaaa tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag
     4981 cagtcaagga ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag
     5041 ctgagcagat tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca
     5101 cccattctgc aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc
     5161 tcaatgacta tatttggcca gcagaatctg agtttactcc cgacatgact accaatgcgg
     5221 tcaaagaagc cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata
     5281 atcccaatgg tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt
     5341 gttatttttc tccgactctc ttttcttcag agacagaaac aactgctgag actataagta
     5401 gaactcgatc catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg
     5461 tagcacctca ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg
     5521 caaaagagct aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa
     5581 ttatcctcaa acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag
     5641 atcatccgtc cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg
     5701 catcttctca agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa
     5761 ttgctccaat tatccagctc caaaaagcgg gagtagcagt cggaattgcg actgactcgg
     5821 ttgcttccaa taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga
     5881 agatgaaaag tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa
     5941 tcgaaggggc taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc
     6001 aagcagattt tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata
     6061 tgctgtctca cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg
     6121 gagaacaggt tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaattacg
     6181 aaaaatttta aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta
     6241 tatacggttt aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc
     6301 gaggacaaaa cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg
     6361 cgtttttctt tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga
     6421 gtgaagcaat tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag
     6481 ctgctgcatc tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc
     6541 ttcgtcgtga gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc
     6601 gtcgtgcagc tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg
     6661 cagtagcatt ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta
     6721 aaaacgctga agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag
     6781 aagagattct tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt
     6841 ctgtacttca agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca
     6901 aagaagacgc ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta
     6961 taaaatttaa aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg
     7021 ctgaaattaa agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag
     7081 aatttggtgt aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg
     7141 gtgctgctaa agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg
     7201 ttatcaaagt tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg
     7261 acggtgcacc agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaag
     7321 ctaaattgga agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat
     7381 tgcggaatcc ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat
     7441 tgatttggtt tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg
     7501 gtagacacta gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag
     7561 gacagtcatc acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg
     7621 taaaagcaac tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat
     7681 ttggaaatgt tggaatttta gtcttggagg gacaataatg aagcgtatta ccgctaatca
     7741 atatcagaca tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta
     7801 taagaatatg aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt
     7861 gtctttgagc aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc
     7921 aaatttgatg gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag
     7981 tgacattttt agatgattac cataaaaaac ataactaccc actattttac gaatcctatc
     8041 ttcaaaacgt tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg
     8101 tagatgatca tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa
     8161 aagagggaat acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga
     8221 ttaacttcgc aaatttatta gattccttaa tttattagat tccttaatcg tctcagaata
     8281 tcaaatggaa ccgaatcttt gggaggtctc ccatgattga tctctatcta agtaaaaata
     8341 gacaaagaaa tcaacttctt ttagatttct tccaaaacta tggcatagag gtatcttgtc
     8401 attcagtttc tgaaatgaca aaggacaaat taattgagat gatgagctat tcttcagatt
     8461 gttttgagtt tttatctccc aatttattac gatttaagaa ccgtgacaat ctaagattaa
     8521 cggatttcgt tgagataatt ttaaaaaatc ctgaactaac catcagactt cctcttgcgg
     8581 tttcaaataa gcgagtttat ccaagtctga atttggaaga ggctagagct ctattgccaa
     8641 gagatacgaa acaattgatt tacatggcgc aaacacatta tttatctaac taaaggagaa
     8701 gcaatatggc tgaacgattt tgggagaact tgtccattat tttggctgaa agaaatatca
     8761 gctggattga gttaaccaga aaaatgtttg cgggagagtt tcactatcca agtgaattga
     8821 atcgtttgta tcaaaagatt cgccactaga agatggaaca atgaatgcct caaagtccat
     8881 gggtagaaag gattgtgcag gtattagatt tagattatga agatttattt cggaggtaac
     8941 tatgaaaaga ataattccag tttatatatt ccaacaagta aatgtcctat tggtatctct
     9001 atacttattg aaatttcttt gtatcggtga gttaactata ctacagattc tctatggttc
     9061 gtcactcatt tcttttttat ggatgtatgg ccaacgcaaa caagcgcata aggtcaatat
     9121 gaaatctagg atgaaatggc ttggtgttga atttgttagc ctactgatta taagtctatg
     9181 ttttagtctg attcatgctc aaggaagcac gaatcaagca aacttaattg gccttcaaca
     9241 tcaaattcct tggttttcat ttttattgtt cttaatcaat gcgagtatgg ttgaagaatt
     9301 tctgtatcga gaaattttat ggaatttggt cagaaaatta gatatcagag ttgctttgac
     9361 aagtgtttta tttgccttag cacatcatac aggaaccatt ctagcttggt gtttgtatgt
     9421 ttcacttggg atgtttttag gtatggtgcg ctataaatct gacttatggg gcagtatggg
     9481 actacatttg gtgtggaacc tactagttta tagtttgctg cttttttaaa ataggtgacc
     9541 tgatttttag gtaacttcta aaactaactt ccagttttgg gagagagatg gaagttactt
     9601 tgaaaagtta cggaaacatt attttctatg tgacaacatt gtataattgc ttgcatttta
     9661 ctggtggaga gagtataatg agggtggata aagtacttaa tcccaaaaat ttaaatagga
     9721 ggagctagct atggcagaag aagtattaaa tcttcaatta gtatctgttc aagttgacga
     9781 aacagatgaa gttgatggaa tgcgatttag tacattcagt acaaa
//
LOCUS       DAVHBD010000054         9698 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000054 DAVHBD010000000
VERSION     DAVHBD010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.054"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            198..293
                     /locus_tag="VVK04_001835"
                     /pseudo
     CDS             198..293
                     /locus_tag="VVK04_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VVK04_001836"
     CDS             complement(546..1166)
                     /locus_tag="VVK04_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU3990460.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTPNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VVK04_001837"
     CDS             complement(1166..1648)
                     /locus_tag="VVK04_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU3990461.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VVK04_001838"
     CDS             complement(1648..2490)
                     /locus_tag="VVK04_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU3990462.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3373)
                     /locus_tag="VVK04_001839"
     CDS             complement(2585..3373)
                     /locus_tag="VVK04_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU3990463.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQALK
                     HLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDKAYKS
                     HITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTMSNMN
                     EGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLESSPKT
                     DLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3517..4896
                     /gene="glmU"
                     /locus_tag="VVK04_001840"
     CDS             3517..4896
                     /gene="glmU"
                     /locus_tag="VVK04_001840"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU3990464.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4906..5451
                     /locus_tag="VVK04_001841"
     CDS             4906..5451
                     /locus_tag="VVK04_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU3990465.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5463..5777
                     /locus_tag="VVK04_001842"
     CDS             5463..5777
                     /locus_tag="VVK04_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU3990466.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHDFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5794..6486
                     /locus_tag="VVK04_001843"
     CDS             5794..6486
                     /locus_tag="VVK04_001843"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU3990467.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANILFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6563..7054
                     /gene="rocS"
                     /locus_tag="VVK04_001844"
     CDS             6563..7054
                     /gene="rocS"
                     /locus_tag="VVK04_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU3990468.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7152..7742
                     /locus_tag="VVK04_001845"
     CDS             7152..7742
                     /locus_tag="VVK04_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU3990469.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7751..9514
                     /locus_tag="VVK04_001846"
     CDS             7751..9514
                     /locus_tag="VVK04_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU3990470.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMDRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3003 a         1681 c         2072 g         2942 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgcaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgtagataa
      121 aacttgtgag gtcaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatcttagt
      301 atagaaaagt gaatctgaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atctcatttt gttctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgcaa taccttttta cgaggctctg
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctaaggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattgg gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgtt cagctggact atcttttaat gatttgataa attggatggt ccgttgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccaaggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactgacca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccact agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaagtctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat catttgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagaaatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaatttgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atatagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaggtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga acccctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agttttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 ttgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgctata ttggattttg ttttaaacga ttggctgtca ttaagtgggc
     3301 gattgatgat taaaatgaac atcataatcc caaaaaaact aaataaaata agtggatgaa
     3361 tttgttttct catatcttat aagtctaccc taaaaatcaa aaaaaatcaa aaaaatgggt
     3421 taaggaagag actttagagc attttttcat tcaagagtgc ggaatgattt gaaatatggt
     3481 ataataaaag ggaatttcta cagaaaagag aagattatgt caaattttgc cattatttta
     3541 gcagcgggta aagggactcg catgaaatct gatttgccaa aagttttgca caaggttgcg
     3601 ggtatttcta tgttggaaca tgttttccgt agtgtgggag ctatccaacc tgaaaagaca
     3661 gtaacagttg taggacacaa ggcagaattg gttgaggagg tcttggctgg acagacagaa
     3721 tttgtgactc aatctgaaca gttgggaact ggtcatgcag ttatgatgac agaacctatc
     3781 ttagaaggtt tgtcaggaca caccttggtc attgcaggag atactccttt aatcactggt
     3841 gaaagcttga aaaacttgat tgatttccat atcaatcata aaaatgtggc cactatcttg
     3901 actgctgaaa cggataatcc ttttggctat ggacgaattg ttcgtaatga caatgctgag
     3961 gttcttcgta ttgttgagca gaaggatgct acagattttg aaaagcaaat caaggaaatc
     4021 aacactggaa catacgtctt tgacaacgag cgtttgtttg aggctttgaa aaatatcaat
     4081 accaataacg ctcaaggcga atactatatt acagacgtca ttggtatttt ccgtgaaact
     4141 ggtgaaaaag ttggcgctta tactttgaaa gattttgatg aaagtcttgg ggtaaatgac
     4201 cgtgtggcgc ttgcgacagc tgagtcagtt atgcgtcgtc gcatcaatca taaacacatg
     4261 gtcaacggtg ttagctttgt caatccagaa gcaacttata tcgatattga tgttgagatt
     4321 gcttcggaag ttcaaatcga agccaatgtt accttgaaag ggcaaacgaa aattggtgct
     4381 gagactgttt tgacaaacgg tacttatgta gtggacagca ctatcggagc aggagcggtc
     4441 attaccaatt ctatgattga ggaaagtagt gttgcagacg gtgtgacagt cggtccttat
     4501 gctcacattc gtccaaattc aagtctgggt gcccaagttc atattggtaa ctttgttgag
     4561 gtgaaaggat cttcaatcgg tgagaatacc aaggctggtc atttgactta tatcggaaac
     4621 tgtgaagtgg gaagcaacgt taatttcggt gctggaacta ttacagtcaa ctatgacggc
     4681 aaaaacaaat acaagacagt cattggagac aatgtctttg ttggttcaaa ttcaaccatt
     4741 attgcaccag tagaacttgg tgacaattcc ctcgttggtg ctggttcaac tattactaaa
     4801 gacgtgccag cagatgctat tgctattggt cgcggtcgtc agatcaataa agacgaatat
     4861 gcaacacgtc ttcctcatca tcctaagaac cagtaggagc ctatcatgga gtttgaagaa
     4921 aaaacgctta gccgaaaaga aatctatcaa ggaccaatat ttaaactggt ccaagatcag
     4981 gttgaattac cagaaggcaa gggaactgcc caacgggatt tgattttcca caatggggct
     5041 gtctgtgttt tagcagtaac ggatgaacaa aaacttatct tggtcaagca gtaccgcaaa
     5101 gctatcgagg ctgtctctta cgaaattcca gccggaaaat tggaagtagg agaaaacaca
     5161 gcccctgtgg cagctgccct tcgtgaatta gaggaagaaa cagcctatac agggaaatta
     5221 gaactcttgt acgattttta ttcagctatt ggcttttgta atgagaagtt aaaactatat
     5281 ttagcaagcg atttaacaaa agtggaaaat ccgcgtccgc aggatgagga tgaaaccttg
     5341 gaagtccttg aagtgagctt agaagaagcg aaagaattaa tccaatcagg tcatatttgt
     5401 gatgccaaga caattatggc tgttcagtat tgggagttgc agaaaaaata gaggaggtca
     5461 gtatgggtaa atctttatta acggatgaaa tgattgaaag agctaataga ggcgaaaaaa
     5521 tttcaggtcc tcctttgcta gatgataatg aggaaactaa gattttacca acctcttctt
     5581 cccgttttgg ttatgccaat cctaaggatc atgattttag ccaggaaacc ttgaagattc
     5641 aggtcgaacc atctattcat aaaagccgtc gtattgaaaa taccaagaga aatgtcttca
     5701 attctaagtt gaataaaatc ttattcgcgg tcatctttct cttgattttg cttgttttag
     5761 caatgaaact tttgtaatag aaaaggaatt gaaatgaaaa taggaattat tgctgctatg
     5821 ccagaagaac tggcttatct ggtccagcat ttagacaatg cccaggagca agttgttttg
     5881 gggaatacct atcatacagg aaccattgct tctcatgaag tcgttcttgt agaaagtgga
     5941 attggtaagg tcatgtctgc tatgagtgtg gcgattttgg ctgatcattt ccaggtggat
     6001 gcccttatta atacgggttc agctggggca gtagcagaag gtatcgctgt tggggatgtc
     6061 gtgattgctg acaaattagc ctatcatgac gtggatgtca cagcttttgg ctatgcttat
     6121 ggacaaatgg cgcaacaacc gctttatttc gaatcagaca aaacctttgt tgctcaaatc
     6181 caagagagtt tatctcaatt ggaccaaaac tggcatcttg gtttgattgc tacaggagat
     6241 agttttgttg caggaaatga caagatagaa gcgattaagt cccatttccc agaagtttta
     6301 gccgtggaga tggagggggc agctattgct caagcagcgc atgccctcaa tctcccagtc
     6361 ttagtcatca gagctatgag tgacaatgcc aaccatgaag caaacatctt gtttgatgag
     6421 tttattatcg aagctggacg tcgctctgcc caagtcttgt tgaccttttt gaaggcttta
     6481 gattaagcgg aaatttgaca gtttttctag cttatgataa gatttaagta aagaaaagct
     6541 agaaaacgtt tcagaggata ttatgagtat tgaaatgacc gtcagtgaga ttgcagaggt
     6601 cttaggatta tctcgccaag caatcaataa ccgtgtcaaa gaattaccag aagaagacac
     6661 agataaaaat gacaaagggg taacagttgt taccagaagt ggcttgatta agctagaaga
     6721 aatctataaa aaaacgattt ttgaagatga gcctgtcagt gaagatgtca aacaacgtga
     6781 actgatggag attctagtgg atgagaagaa tgcagaaatt cttcgtcttt atgaacaatt
     6841 aaaagccaag gatcgtcagt tatcagaaaa agacgagcag atgcgtatca aagaccgtca
     6901 gattgctgag aaagacaaac aattagatca gcaacaacaa ttgacccttc aagccatgaa
     6961 ggatcaagaa aatcttaagc tagagctgga ccaagcaaaa gaagaagtcc aatccactaa
     7021 gaaaggcttt tttgctcgtt tatttggagg ataatcaagg agctgtttag gttaaatgct
     7081 aacctgatgg cttcttttgt ttgtgaatag tatagttgat tagaacagag acagtagagg
     7141 agaggtacag aatggaacga ttagaagatt acattgcttt tgacttagaa tttaatcagc
     7201 acgaaggaca aacacacttg attcaagtat cggcagtgcg ttttagagat ggtcgggaaa
     7261 tcgatgccta tgattcctat gttcatacca gcgtccctct aaaaagcttt atcaatggtt
     7321 tgaccgggat tacagctgag accttaaaag atgctcctcc agttgagaaa gtcttagaag
     7381 aattccaaga gtttgtgggt tctttgctga tgataggcta caatgctgct aaaagtgatt
     7441 tacctatttt agcagagcat ggtttagact atagccaaca gtacaaggtg gatttgtatg
     7501 atgaagcttt tgaacgtcgg agttcagatt tacatggtat tgccaatctc aaattgcaaa
     7561 ctgttgcctc atttcttgga tttcaaggtc agtctcataa tagtttagag gatgctcgga
     7621 tgacggcgcg tgtttacgaa tccttcttag agtcggatca agctagggaa ttgttagaga
     7681 cagaaagtag cttatcaaac aatccttttg gtggcttgga cttgtctcaa ttatttgact
     7741 aggagtgcct atgaaacctg aaaaacctaa aaaattgggt cttaaacaga tttacctcaa
     7801 tcttgataaa atcctctttc tatttttctt gatttttatg atagtggagt atttgtgggt
     7861 accattcaat tcatggttgg ctagcttctt attagatcag acaggttatc tttttatttc
     7921 ctataacaat gtcttagcca tccttactca ttctccattg attagtctag cttttttagc
     7981 cttgattgta attaaccttc tggttgctta ttttcaaata ggactcctct ttattggtgc
     8041 tcgtcatctc ctatataatg aaaagcgaag gctaattgag tatatccgca aggttttcca
     8101 tgaaagtttt ggatttatga aaaagctaac tggcgctaaa gccttgttta tctttttcta
     8161 tatagctatg ctttttcctt ttatacggaa aatgctgaag atttattatc ttaataaaat
     8221 cgtcattcca gagtttatcc aagcttattt agaagataaa tattggatgt ggtggctgag
     8281 catcctactt ctatctctta tctttctcta tgtctctgtc agattgatgt ttgcccttcc
     8341 gaagattgta tatgatcagc tgactgttcg agaagcagtg atgtttagct tggagaaaac
     8401 caagaagaga gttacttttt atgcttggaa tttattttac atcttgctca aagcacattt
     8461 attattttat cttcctttga ttcctttatt attggctcaa actttggtag atgatatcac
     8521 tcagagagag tctctgattc ttggtatttt gaattttgtc gtgattaaaa atctctatta
     8581 tatggctctg acttattttt tggttaaatt tgtttcattt ttgacaggaa aggagctgga
     8641 tatgcttcct aggagagaaa aagatcacat cgtgcgatgg ggtgtcatga cttgtgccag
     8701 tcttttcttt gccttagaag gttatattta tctggaggct cccatggttc atctacctca
     8761 acttatttct caccgagggg tttccaatgc aaatgggatt caaaatacag tagagtcctt
     8821 ggaaactaca gcacaactca aaccagactt ggtggagacg gacgtgcagg aaacaaaaga
     8881 tgggcagttt gtcatgatgc atgatgctaa cttgaaaaat ctagcaggta tcaataaaag
     8941 tcctcaagac ttaaacttgg aggagcttaa agggattgat atttttgaaa atggctacca
     9001 gactaaaatt tcaagctttg aagattatct cagtcgagcc aacgaacttg gtcaaaaatt
     9061 actaattgaa attaaaacca gtaaaaaaga tagtccagac atgatggacc gctttttagc
     9121 ccgttatgct gcaaagctca agatttatgg acatcaaatc cagtctttag actaccatgt
     9181 tgtcgaaaaa gtaagacagt atgatgccga actgccagtt tatttcatca tgccctacaa
     9241 ttctgtcttt cctaaaacaa gagcgacagg atatactatg gagtactcaa ccttggatga
     9301 atattttgta agcaaactat ggacaacgga tcagaaactt tatgtctgga ctgtcaatga
     9361 ttcagaagct atcagcaaat ctcttcactt aggagtagat ggagtgatta cagatgattt
     9421 ggaaaaagtt cagcgggaaa tagaagtagc ccaagaagat ccagaatata cggatttgct
     9481 cttgaaaaaa gcattggaat tctttgaatt ttagtaataa aaaagaggaa cggttgttcc
     9541 tcccatgata ggtaagtatt cttgtgaatg cttgcttttt tgtggttgca atccgtttac
     9601 gagaattgtt tgtattgttc ttgtttcaat ttactttata gtgctttgaa gttggaatgc
     9661 tacactataa cttctaaaat atagtaaaat gaaccaaa
//
LOCUS       DAVHBD010000055         9675 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000055 DAVHBD010000000
VERSION     DAVHBD010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9675
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.055"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            32..496
                     /locus_tag="VVK04_001847"
     CDS             32..496
                     /locus_tag="VVK04_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU3990471.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            652..1077
                     /gene="lacA"
                     /locus_tag="VVK04_001848"
     CDS             652..1077
                     /gene="lacA"
                     /locus_tag="VVK04_001848"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU3990472.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            1108..1623
                     /gene="lacB"
                     /locus_tag="VVK04_001849"
     CDS             1108..1623
                     /gene="lacB"
                     /locus_tag="VVK04_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU3990473.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1634..2563
                     /locus_tag="VVK04_001850"
     CDS             1634..2563
                     /locus_tag="VVK04_001850"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU3990474.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLNKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2565..3545
                     /gene="lacD"
                     /locus_tag="VVK04_001851"
     CDS             2565..3545
                     /gene="lacD"
                     /locus_tag="VVK04_001851"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU3990475.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            3779..4615
                     /locus_tag="VVK04_001852"
     CDS             3779..4615
                     /locus_tag="VVK04_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU3990476.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4651..4968
                     /locus_tag="VVK04_001853"
     CDS             4651..4968
                     /locus_tag="VVK04_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU3990477.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            4968..6659
                     /locus_tag="VVK04_001854"
     CDS             4968..6659
                     /locus_tag="VVK04_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU3990478.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWVFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            6874..8280
                     /gene="lacG"
                     /locus_tag="VVK04_001855"
     CDS             6874..8280
                     /gene="lacG"
                     /locus_tag="VVK04_001855"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU3990479.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNSKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAVADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8370..8510
                     /locus_tag="VVK04_001856"
     CDS             8370..8510
                     /locus_tag="VVK04_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU3990480.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWDTISFDSDFMPFQ
                     QS"
     gene            complement(8789..9550)
                     /locus_tag="VVK04_001857"
     CDS             complement(8789..9550)
                     /locus_tag="VVK04_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU3990481.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
BASE COUNT         3051 a         1726 c         1952 g         2946 t
ORIGIN      
        1 taaagaaact agcaaggtca ggccttactt tattggtgga catccaggat ttaattgtct
       61 tctacttgat gatgaagtct atgaagatta ttatctagag tttgagaaag aagagacttg
      121 ctctgttcca cgtcctttcc cagaaacagg tatgttggat ttccaagata gaagtccatg
      181 gctagaggga caaaaagaaa tagatcttag ttatgatctt ttcagcacag atgcagtgac
      241 tttggatgaa ttgcaatctc gaacaattgc ccttcgttct cttaaacatg ataagggatt
      301 gaaagtgcat tttgcagaat ttccaaacct catcatctgg tcaactttga acaagggacc
      361 tttcattacc tttgaaccat ggtctggctt gtcaacattc cttgaagaag gagatcattt
      421 agaagataag aagaatgttt gtctcttaga agccaatcag gttgaagaat tagggtttga
      481 gatagaagtt ttataaaaaa gtaaaaaata aataacaaaa acaaacacaa actattgact
      541 tcttcaaaca atagtagtat attatgtttg tgaggactaa ttgactgttt tttaaagaca
      601 gccaatacac tgctggaatc cagcatagaa aaataaaaag gagtatacaa tatgtctatt
      661 gttatcggtg cagatgctgc aggtttgaga ttgaaagaag ttgtgaaaga cttcttagaa
      721 aaagaaaact tccaccttgt ggatgttaca gctgaaggtc aagactttgt tgatgtgact
      781 ctcgctgttg ctgcagaagt aaacaaagaa gaacaaaacc ttggtatcgt gattgatgct
      841 tacggtgctg gtccatttat ggtcgcaaca aaaatcaaag gaatggttgc tgcagaagta
      901 tctgacgaac gttcagctta tatgactcgt ggccacaaca actcacgtat gatcactatg
      961 ggggcacaac ttgttggtga tgaattggct aaaaacatcg ctaaaggatt tgttaatggt
     1021 aaatacgacg gtggacgtca ccaaattcgt gtcgacatgt tgaacaaaat gtgctaatta
     1081 gattacagta agaaaggtaa gttaaaaatg agaattgcaa ttggatgtga ccacatcgta
     1141 acagatgaaa aaatggcggt ttcagaattt ttgaaatcaa aaggatatga agtcattgac
     1201 tttggtacat atgaccatac acgtactcac tacccaatct ttggtaaaaa agtaggggaa
     1261 gctgtaacta gcggtcaagc tgatcttgga gtatgtatct gtggtactgg tgttggtatc
     1321 aacaacgctg taaataaagt tccaggtgtt cgttctgcct tggttcgtga tatgacaaca
     1381 gccctttatg ctaaagaaca attgaacgct aacgttattg gttttggtgg taaaattact
     1441 ggtgaattgc ttatgtgtga tatcatcgaa gctttcatcc atgctgaata caaaccaact
     1501 gaagaaaaca aaaaattgat tgcgaaaatt gaacatgttg aaagtcacaa tgctcaacaa
     1561 acagacgcaa acttctttac agaattcctt gagaaatggg atcgtggaga ataccacgac
     1621 taagaggtga cctatgattt taacagtcac aatgaaccca tccatcgata tttcctatcc
     1681 cttggatgag ttgaagattg atactgtcaa tcgtgtggtg gatgtaacca aaacggctgg
     1741 tggtaaggga ctcaatgtta cccgagtact ttcagaattt ggcgattctg ttcttgctac
     1801 tggtttagtg ggtggcaaac ttggtgagtt tttggttgaa catatcgata atcaagtaaa
     1861 gaaagatttc ttctcaatta agggagaaac tcgtaactgt atcgctattc tccacggaga
     1921 caaccaaaca gaagttcttg aaaaaggtcc tgaagtattg gaacaggaag gtcaagactt
     1981 tttggaacat ttcaaaaaac tcttggagtc agttgaagta gtagccatct caggtagtct
     2041 gccagctggc cttccagttg attactatgc gagcttggta gaacttgcta atcaagctgg
     2101 caagcctgta gtcttggact gctcaggtgc agcacttcag gctgttcttg aatcacccca
     2161 taaaccaaca gtcatcaaac caaataatga agaattgtct cagcttcttg gaagagaagt
     2221 ttctgaggat ttggatgaat taaaagaagt acttcaagaa cctttgtttg cagggattga
     2281 atggattatc gtttcacttg gtgccaacgg tacttttgcc aaacatggtg acactttcta
     2341 caaggtagat attcctagaa ttcaggtggt aaatcctgtt ggatctggag actctactgt
     2401 ggcaggaatt tcttcaggac ttcttaacaa agaatcggat gcagaattac tcatcaaggc
     2461 aaatgtcctt ggtatgctca atgctcaaga aaaaatgact ggtcatgtca acatggccaa
     2521 ctatcaagct ctatatgatc aattaatagt aaaagaggta taaaatggct ttaacagaac
     2581 aaaaacgtgt acgcttagaa aaactttctg atgaaaatgg tatcatctca gctcttgcat
     2641 ttgaccaacg tggtgctttg aaacgcctca tggctcaaca ccaaacagaa gaaccaactg
     2701 tggcccaaat ggaagaactt aaagtcttgg tagcagatga attgactaaa tatgcttcat
     2761 ctatgcttct tgaccctgag tatggacttc cagcaactaa agctcttgat gaaaaagctg
     2821 gtcttctcct tgcttatgaa aaaacaggtt atgacacaac aagcacaaaa cgcttgccag
     2881 actgcttgga tgtttggtct gcaaaacgta ttaaagaaga aggtgcagat gcagttaaat
     2941 tcttgcttta ctatgatgta gatagctcag acgaactcaa tcaagaaaaa caagcctaca
     3001 tcgaacgcat cggttctgag tgtgtggctg aagatatccc attcttcctt gaaatccttg
     3061 cttacgatga aaaaattgcg gatgcaggtt ctgtagaata cgctaaagta aaaccacaca
     3121 aagttatcgg cgctatgaaa gtcttttcag acccacgctt taacattgat gttttgaaag
     3181 ttgaagttcc tgttaacatt aaatatgttg aaggcttcgc tgaaggtgaa gtagtttata
     3241 cacgtgaaga agcagcagcc ttcttcaaag cgcaagatga agcaacgaac ttgccataca
     3301 tctacttgag tgctggtgta tcagctaaac tcttccaaga tactcttgta tttgctcatg
     3361 aatcaggtgc aaactttaac ggagttcttt gtggccgtgc tacatgggca ggatcagttg
     3421 aagcttacat caaagatggt gaagcagcag ctcgcgaatg gcttcgcaca actggatttg
     3481 aaaacattga cgaactcaac aaagttcttc aaagaacagc aacttcatgg aaagaacgcg
     3541 tgtaagaaag tcctcctagt ttaggaacat gaatctaaaa aaatttaaaa aaagttgtat
     3601 gtaaaggttt acaaaacaac cgacttgtgc tatacttaaa tcacaagtta atacaaggtg
     3661 agtgttacta agtaatatta ggcatgatca caggtgaatt agaaatcagc tgattttcta
     3721 gttcatttgt ggtcattttt tgtactcata tacctttaag atataaaagg aggttgacat
     3781 gtatcgaatt ctaaatccaa tgaatcacaa tgtctcgctt gtcagaaatg ataagggaga
     3841 agaggtgatt ataattggta aggggattgc attcggaaaa aggaaggggg atttgattgc
     3901 tgaaaatcag gttgagaaaa tctttcggat gaagaccgaa gagtccagag aaaactttat
     3961 ggctcttctc aaagatgttc cgcttgattt tatcacagtg acctatgaaa tcattgataa
     4021 gctatcaaag aaatatcatt atccgattca agagtatctc tatgtaacct tgacagatca
     4081 tatttactgt tcttatcaag ctctaactca aggaaggtac aaggatagta atctgccgga
     4141 tatttccgct aagtatcctg tcgcttttca aatcgcaaat gaagcttttg aaatttaccg
     4201 tcagaagcta gcagatcatt ttcctgagga cgagattatt cggattgctt atcatttcat
     4261 caatgccgaa ggtgaaaatg aagtggaact tgtggagtcg attgataaga ggaaagaaat
     4321 tctcaggaat gttgaagaag tgctaaaggg ttatgcaatt caacgaacca aaaaaaataa
     4381 tcatttctat gatcgcttta tgattcattt gaattatttc ttggattatt tagacagatc
     4441 tagagatgat aaccaatcac ttctggatat ggaagatcat attaaacaat cctatccaaa
     4501 agccttcgag attggttcca agatctatga tgtgattacg caacatacgg gtcttgattt
     4561 gtataaaagt gaacgagttt atctagttct acatatccaa cgtttattgt cataaaaatt
     4621 tatttaaaac tatataagga gaattctatt atgaatagag aagaagtaac attgttaggt
     4681 tttgaaatcg tagcctatgc tggcgatgct cgttcaaaac tattggaagc cttgaaggct
     4741 gctgaagctg gtgattttga aaaagcggac gctctggtag aggaagctgg ttcttgcatt
     4801 gctgaagctc atcatgccca aacaagtcta ttgactaagg aagcttcagg tgaggacttg
     4861 gcttatagtg taaccatgat gcatggccaa gaccacttaa tgacaactat cttgttaaaa
     4921 gatttgatgc atcatttaat tgaactctac aagagaggag ttaaataatg aataaactaa
     4981 ttgcatttat cgagaaagga aagcctttct ttgaaaaact atctcgtaat atctatcttc
     5041 gtgctattcg tgatggtttc attgcaggta tgcctgttat tctcttctca agtatcttta
     5101 tcttgattgc ctttgtacca aactcatggg gctttaaatg gtctgatgaa gttgtagcct
     5161 ttctgatgaa accttatagc tattctatgg gtattctggc tctcttggta gctggtacaa
     5221 cagctaagtc attgaccgac tcagtaaacc ggagcatgga gaaaaccaat caaatcaact
     5281 atatgtcaac gctgttagca gcgattgttg gtttgttgat gttggcagct gatcctatcg
     5341 aaaatggtct agctactgga ttcttgggga caaaaggttt gctttcagcc ttccttgctg
     5401 cctttgttac tgtagccatc tataaggttt gtgttaagaa caacgtcact attcgtatgc
     5461 ctgacgaagt tccaccaaat atctcacaag tctttaaaga tgtgattcca ttcactctct
     5521 cagttgtttc actttatgct cttgatttac tagctcgtca ttttgttggt gcaagcgtag
     5581 ctgaatcaat cggtaaattc tttgcaccac tcttctctgc agctgatggc tatcttggta
     5641 ttaccattat ctttggtgcc tttgccttct tctggtttgt tgggattcat ggtccatcta
     5701 tcgttgaacc tgctatcgca gcgattacct atgcaaatgc tgaagtcaac ttgaaccttc
     5761 tccaacaagg tatgcacgct gacaagattc ttacttctgg tacacaaatg tttatcgtta
     5821 ccatgggtgg tactggtgcg acactggttg ttccattcat gtttatgtgg ttaacaaaat
     5881 caaaacgtaa ccgtgcaatc ggacgtgctt cagtagttcc taccttcttc ggtgtaaatg
     5941 aaccaatctt gtttggtgca ccacttgtat taaatccaat cttcttcatt ccatttattt
     6001 ttgctcctat cgcaaacgta tgggttttca aattctttat tgaaacactt ggaatgaatt
     6061 catttactgc taatctacca tggacaaccc cagctccact aggtctagtt cttggaacta
     6121 acttccaagt tctatcattc attcttgctg ctcttctaat cgtggttgac gttgtcattt
     6181 actatccatt ccttaaggtc tatgatgaac aaattcttga agaagaacgt tcaggtaagt
     6241 ctaatgatga attgaaagaa aaagttgctg caaacttcaa cactgcaaaa gcggatgcta
     6301 ttcttgaaaa agcaggtgtc gatgcagcac aaaataccat cactgaagaa acaaatgtcc
     6361 tcgttctctg tgctggtgga ggtacaagtg gactccttgc aaatgctttg aataaggcag
     6421 cagcagaata caatgtccct gtgaaagcag cagcaggcgg ctatggtgct caccgtgaaa
     6481 tgttaccaga gtttgatttg gttatccttg ctcctcaagt tgcttcaaac tttgaagata
     6541 tgaaggcaga aacagataag ctcggtatta aactagcgaa aacagaaggc gctcaataca
     6601 tcaaattaac tcgtgatgga aaaggtgccc tagcattcgt acaagaacaa ttcgattaag
     6661 gctaggaact gtgaaacagt ctcctatcgt tacggaaatc gctatggcga atttcctaat
     6721 cgccttatta attcgtcggt aaaaagatat cgtttttacc tcctcatgtc acaattcggt
     6781 gacttggtac aagaagtgag atggagaagg atggctcact gactcctctc ctctcacttt
     6841 tactttattt aaatcaagaa ataggtgaaa aaaatgacaa aaacacttcc aaaagacttt
     6901 atttttggtg gcgcaacagc tgcctatcaa gcagaaggtg ctacacatac tgatggtaaa
     6961 ggaccagtag cgtgggataa atatcttgaa gataactact ggtacactgc agaaccagcc
     7021 agtgattttt acaatcgata tccagttgat ctcaagctag cagaagagta tggtgtcaat
     7081 ggcattcgaa tttctattgc ctggtcacgt attttcccga ctggttatgg tcaagtaaat
     7141 tctaaaggtg ttgagtttta tcataattta tttgcagagt gtcacaaacg tcatgttgaa
     7201 ccctttgtaa ctcttcatca ctttgacacg ccagaagctc tccactcaaa tggagacttc
     7261 ttaaaccgtg aaaatatcga acattttgta gactacgctg ccttctgttt tgaagaattt
     7321 ccagaagtaa actattggac aaccttcaat gaaattggac caatcggtga tggtcaatat
     7381 ttggttggga aattccctcc aggtatccag tacgaccttg ccaaagtctt tcaatcacac
     7441 cacaatatga tggtgtctca tgcatgcgcg gtaaaattgt acaaagagaa aggctataaa
     7501 ggggaaattg gtgttgttca cgccctgcct actaaatatc ctctagatcc tgaaaatcca
     7561 gcagatgttc gtgcagcaga gttggaagat atcatccaca ataaattcat cttagacgca
     7621 acttatctag gtcgctattc agctgaaacc atggaaggtg tcaaccatat cttatcagtc
     7681 aatggtggta gtttggatct tcgtgaagaa gattttacag cattagaagc tgcaaaagac
     7741 ttgaatgatt tcctaggaat caactactat atgagtgact ggatggaagc ctttgatgga
     7801 gaaactgaaa ttatccataa tggtaaaggt gaaaaaggaa gctctaagta tcaaatcaaa
     7861 ggtattggtc gtcgtgtagc tcctgactat gtatcacgca cggattggga ttggattatc
     7921 taccctcaag gtttgtatga ccaaatcatg cgtgtgaaga aagattatcc taactacaag
     7981 aaaatttaca tcactgaaaa tggtctcggc tataaagatg agttcgttga taacactgtt
     8041 tacgatgatg gtcgtattga ttacgtgaaa caacacttgg agatcttgtc tgatgcggtt
     8101 gcagatggag ctaatgtaaa aggttacttc atttggtcat taatggatgt cttctcatgg
     8161 tcaaacggtt atgagaaacg ttatggtctc ttctacgtag attttgaaac tcaagaacgt
     8221 tatcctaaga aatcagctca ctggtacaag aaagtagcgg aaactcagat tatagactag
     8281 tagaattagt cattagatat agaattttag tgagtcaaaa agatgttcaa agattttatc
     8341 caatctattt atgaaaaaaa gtttatatta taaatttcga aaaatgctct caaataccgt
     8401 gtttgacgag tgaagaattg aaaagtcttg gaaaatggta tgtctcgact ggtaaagaat
     8461 gggatactat ctcctttgat tcagatttta tgccgtttca acaatcgtaa ccaatttctc
     8521 aaaaaagtta aatcttatat ttagtactct gtaaaactct tatctaatca cgttgcttat
     8581 actcaatgaa aatcaaagag caactttaaa ctaggaagcg agtcgcagat ttctcaatgc
     8641 atagctttga ggaattgggc aaaaagtctt tgatatagaa aaaagcatag tatcaggtgt
     8701 tgaaacacct gatactatgc tttttattgt gggaagattt actttttttc ttctgaaatt
     8761 gagttgttac ccaggctctt tcagtttatt aaggcttgat gactttaatg tgtttagata
     8821 gcttaaaaag gattgaatca cttagtttag aatctgaaac aatagtatca agatttgata
     8881 tattataaaa agtataaaaa tcaaacttat tgaacttgct atgatctgcg agtaaatatt
     8941 ttttattaga attatttaaa gcgatgcgtt gagcctctcc ctcttcctcg ctaaaagtag
     9001 ctagagctcc attttgaata ccattacagc taacgaaagc tttagaaaat tggagattag
     9061 agagattttg tagggtcaat gtgccaacaa aagcacctgt aatatcgcga taatttccac
     9121 ctatcaaaat caaatctgtt aattttcgtt cgcttaaaat cagaaaaaca ggtagactgt
     9181 tggttacgac gcggatattg tcaataggca attcgcgcgc aaaaaattct aatgttgttc
     9241 ctggtccaat gaaaatagtt tctctttctt ctactagact gcctgcaaaa tgggctattt
     9301 cttgtttttc tgccgtttgg agggcttgtt tttcaatatt tgatcgctca ttagtcaaaa
     9361 gggagttggt tcgaagtttt tcagctccac catgcacacg aatcagcaaa tctttatcag
     9421 ctaattcctg taaatagcgc cttgcagtca tatctgaaac ggctatttcg tccataatct
     9481 gtttaaccgt tatggttcct ttgctattta ctatctctaa aattttggtt aatttttctt
     9541 gtttgagcat attatcacct cgtttcctac tactatctta ccataaataa actcatcatt
     9601 caaatacaaa aacaacaaaa tgaaacaaaa acaaaaatat cgaagtttgt tttcaaaact
     9661 ttcgatattt ttggg
//
LOCUS       DAVHBD010000056         9428 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000056 DAVHBD010000000
VERSION     DAVHBD010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.056"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..116
                     /locus_tag="VVK04_001858"
     CDS             <1..116
                     /locus_tag="VVK04_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU3990482.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="VVK04_001859"
     CDS             140..1063
                     /locus_tag="VVK04_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HEU3990483.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDEKFNLLYEQDGKISPDKGITIEVENEIYYILGSSIYRITIGESVEETC
                     IGNFDFQLESGYGCYFDGHLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYSLKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNE
                     IVYNKAVIDLATPGYREEYFSKGRDFFNWNRSMRILDLETGKVKIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="VVK04_001860"
     CDS             1145..2773
                     /locus_tag="VVK04_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU3990484.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDFSESGKEKVFYL
                     SGFLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGDFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLSKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2883..3833
                     /locus_tag="VVK04_001861"
     CDS             2883..3833
                     /locus_tag="VVK04_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990485.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFASGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3850..4701
                     /locus_tag="VVK04_001862"
     CDS             3850..4701
                     /locus_tag="VVK04_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990486.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4714..6696
                     /locus_tag="VVK04_001863"
     CDS             4714..6696
                     /locus_tag="VVK04_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990487.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDNVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHDITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKEALKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            6706..8115
                     /locus_tag="VVK04_001864"
     CDS             6706..8115
                     /locus_tag="VVK04_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990488.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDTKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            8120..8608
                     /locus_tag="VVK04_001865"
     CDS             8120..8608
                     /locus_tag="VVK04_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEU3990489.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            8896..9303
                     /locus_tag="VVK04_001866"
     CDS             8896..9303
                     /locus_tag="VVK04_001866"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU3990490.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGASQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
     gene            9335..>9428
                     /locus_tag="VVK04_001867"
     CDS             9335..>9428
                     /locus_tag="VVK04_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEU3990491.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRA"
BASE COUNT         3222 a         1338 c         1783 g         3085 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 tgagaaattt aatcttctat atgaacaaga tggaaaaatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tggtgaaagt gtagaagaaa cctgtatcgg gaattttgat ttccaactag agagtggtta
      481 tggttgttat tttgatggcc acttattctt tggatttcag gaaagttatt tgttcaatat
      541 tgagactcaa gagcttttta aaaaatctga cttcccagtt tctggtagag gccaaggttt
      601 gtcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatagtt taaaaaaaga taagtgggaa aaacttgagt tcgaattacc
      721 aagctcagtt ctaggagcat caagtataca aataaatgaa agtggtttat taatacttgg
      781 tggctttaat gaaattgttt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatat ttttctaaag ggagagattt ctttaattgg aatcgtagca tgcgaatact
      901 agatttagag acaggtaagg tcaagattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat ttttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gttttcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatggatt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 tgactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa gtaaaaaacc aattgatatc ctattctatc gctactttat
     2041 cgctaactta gcaggtgtcg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tggtttattg aatcatgtat ctctcactct tgttttttca ggagaaatta
     2881 aaatgaaaaa atatattcta aaaaaagtat tattcatgat tcctatgttg ttgattatta
     2941 gctttttagt attcattgca ctagatttaa caccagcaga tccattgaca tatatggtat
     3001 ctccagatat ggctagtagt gcagaacaaa tcgaaaagct aagacagcaa ttaggtttaa
     3061 atgatccagt attagttcgc tatggaagat ggctttggca attactccat ggtgattttg
     3121 gatacagtat tgtaaatggt aacccaattt ccaaaattgt aggacaagca ttgcctgcaa
     3181 cttttgaatt agcttttgtg tcattaatta tttcaacaat tgttggtatt gtaattgggg
     3241 ttatatcagc cgttaaacaa aatggtatta tcgataatgt tgctcgtttt ctagctgtta
     3301 tcggaactgc gattccacaa tttttctttg gtattttaat tttaaacttc tttgcaattc
     3361 agttaagaat tttacctatt ggtggtagat ttgccagtgg agattttaca tttattaata
     3421 gagttgaaca cttaattcta ccagtaatgg ctatgtcaat tgcattggta gctgctttaa
     3481 tgagatacac acgtaattct atgttggatg tttttaatgc agattatgtt aaaacagctc
     3541 gtgcaaaagg tgttcctgaa tggaaagttt attttaaaca catatttaga aatgctatgc
     3601 gaccaatttt agtgttattg attttccgtc taccaatgtt aattggtgga tcagtaatta
     3661 tcgagagtgt cttttcttgg cctggaattg gttctatcat cctatctagt gtaacagcag
     3721 gtgactatcc tgtaattatg attaccacat taatgatttc tgtcgtagtg ttatttgcta
     3781 gtctacttgt agatattatg gctgcaatat tagacccacg tattcgttat taggaaggag
     3841 gtcaatgtta tgaaacctat gcctttatgg aaaagaaatt tgaaaaaatt ctataataac
     3901 aaattggcct ttatcggctt tatatgcttc atgctaattc tattagcatg tattctagca
     3961 cctttattga caacctattc tccagatgtt gttgatttag gatctatgaa ccgtcctcct
     4021 tcagcaaaac acattctggg aacagataaa ctaggtcgtg acgtatttgc tcgaatccta
     4081 tatggtggtc gagtttcaat tcaagtcggg atgtatggag cgatttgtgg agcggttatt
     4141 ggtactgtac ttggtggtat tgctggatat tttggtggga aaattgatgc tcttctagtt
     4201 cgtctagcag aattattctt aacattcccg aatatgattg tcattctctt gctttcaagt
     4261 atttttggac aaggtgtatt caatcttatc ttcgtattct cagtaatggg ttggatgaca
     4321 acgttccgaa tggttcgtaa tgagttcatg tctttgaaac aagaaacata tgtggatgta
     4381 tgtagagctt ttggtttttc tgacagtcga attatcttta ataatatttt aagaaatgct
     4441 atctcaccag taattgtatc gttgtcttta aacgttgctg gtttcattct cagtgaggca
     4501 ggtcttagtt tcttaggagt aggtgttcct tctgatattc ctacttgggg aaatatcata
     4561 aatgctgcca aaacagccga tgttattaaa aatagttggt ggttgtggtt agttccaggg
     4621 tcaatcatta ctcttttcgt tctgtctatc aactttattg gtgatggatt acgagatata
     4681 atggatccga aacaacagta ggaggttgac aaaatgaatc aaacagtttt agatgtaaaa
     4741 aacttaaaaa ctgaattcat cactgataaa aaagcatttc cgattattaa agatgtaaac
     4801 ttcactttgg aaagagggaa agttttaggg attgttggtg aatctggatg cggtaagagt
     4861 gtaacagtga atacagtgtt aaacttatta cctaaaaatg gacgcattgc tgaaggtgaa
     4921 atcacatatt tcgatgaaga taagccgata gagcttcaaa aattaaagca atatggtaaa
     4981 gaatttcgaa agttacgtgg tgaaaacata tcaatgattt tccaagatcc aatgtctgca
     5041 ttgaatccag tatatacaat tggtaatcaa attactgaag tccttcatga acattatgac
     5101 atttctaaag aggaggcaaa taaacgtgct atagaaatgt tagaaaaact tggaattcat
     5161 aatgctgcag aacgcatgaa tgactatcca caccaattta gtggagggca gcgtcaaaga
     5221 atagtcatag cgattgcaat ggtatgtaat ccagatattc taattgcaga tgaaccaaca
     5281 actgcccttg atgtaacaat ccaagcacaa atacttgatt tacttgatga tttacgtaaa
     5341 gagcatggaa cttctattat cttaattact cacgatttag gcgttattgc tcaaattgcg
     5401 gatgaagttg cagtgatgta tgctggtgaa gtcgttgaag ttggaactgt agctcagatc
     5461 tttgatcaac ctaaacaccc gtatactcgt tctctattaa gatctattcc taatcctgaa
     5521 aatatggata aaaagctaca tgttatccag gggagcgtac cttcaatttc tgaaatatct
     5581 gaaaaaggat gcagattcgc aaatcgtatt ccatggttag aaaaagaaca tcatgaagaa
     5641 gaacctcaat tgcatgattt aggtgacgga cattttgtaa ggtgttcttg ctataaacat
     5701 ttctttttcg aagataagga agaagaaaca ttagcggaaa aacatgtagg taatgttgtt
     5761 ttagaagtaa aaaatattaa aaagtactac tatcctaaga agcaactatt caagccacta
     5821 ggttctccgt tgaaagcact tgataacgta tctctagagt taagaaaagg aactactatt
     5881 ggtatcgtag gagagtctgg aagcggtaag agtacgattg cgaaatcatt aatgaaactc
     5941 catgatatta cagatggtga aatcaatatt gatttgaatg ggaaaactca aaatatttat
     6001 ggaattaaac gtaaggaaga tttggatttc cgtaagaaag ttcaaatggt attccaagat
     6061 ccttatgcat cattgaaccc aactaagaaa atttataatt catttgatga accgatgatt
     6121 gtccataata ttggaaacaa agaggaacgc tttgaacgta tgaaagaagc cttgaagatg
     6181 gtaaacgtgc cagttgagta cttggagcgt tatcctcatg aattttcagg cggacaacgt
     6241 caacgtttat gtattgctcg tgccctttgt atgaaaccag aaattttaat tttagatgaa
     6301 cctgtttcag cattagatct atctgtacaa gcgcaagttt tgaattatct tgttgaaatc
     6361 caaaataaag aagatttgac ttatgtattt atttctcatg acctaggtgt tgtgaaatac
     6421 atgtgtgact atctatatgt tattcataaa ggacgtattg tagaagctgg ttctcgagaa
     6481 gatatctaca ataacccaat gcatatttac actaaaaaac tattagctgc tattccagaa
     6541 gttgattatc acttcaaaga ggcattggca acaaaacgta aagaaaatga agttgaattt
     6601 aaagcacagt accatgaatt ttatgatgaa gatggtcgtg cttatgatct taagcaggtt
     6661 tcaccaacac attttgtagc gttaaaacca gaataggtgg taaatatgaa attaaataaa
     6721 aaaatatatt tctttgataa aggaattttt aatccttatc gaatgagtaa tgtaaaatta
     6781 aaagttaatc aggcagtaaa ggataaagaa attttcttca ctgaggaaaa accatgggaa
     6841 attcgttttg ataacagtta tccaaatgtt ttctttgatg atttagcagg tgtttatcgt
     6901 tgctactatt ctacatttac tgatgatgag gagtctgaaa aatactcttt agaggagcgt
     6961 aaggaacgtc aatatctacc tcgtgcgaag cgtattgttt cactttgtta tgctgaaagt
     7021 aaagatggtg ttaactgggt gaaaccaaat ctaggtatta cagaatttcg aggatcaact
     7081 gaaaataata ttatcggaca ttttttacat ggtacatctg tttttctaga taaacatgac
     7141 gcagatgaaa atcgtcgtta taaaatgttt acaaagattg attacggtaa cggtgttcat
     7201 ttcattgctg tagcattttc aaaagatggt ctacactttg atgaatacat taaagtacca
     7261 aacttcaatc cacgtgcaga cactcataac catatcatat atgatgaagc attaaatcgc
     7321 tatgtgctaa ttactcgtac ttggagagat tcattgcgct tgccgtgtgt atctacgagt
     7381 gctgatttca ttaactggac tccaattcaa gaaattttga atgtctgtga ttatgaaaat
     7441 caaatttatt ctatgcctat ttttaaacgt ggcgattata tactaggttt agcttcagtt
     7501 ttccatgaag gagatcaact gaacaagaat tacgatacag tggaccttca attgacttat
     7561 agttatcgtc atgttggttg gcattatcta aacactgata ctccacttat tcctcgtggt
     7621 aaaggtcaat atggtgatgg agaatttgac tgtggatgta tctattcttc tgcaccagtt
     7681 actatcggtg accgtactta tttctactac atgggaggaa atggacaaca tacaaacttc
     7741 cgtgaaacaa gcttgtctcg tgcttatatt gagaaagatc actttgcata ttgggatact
     7801 aaacgtccag aatatccagg tgttttgtat accaatggat ttattttcct caatgatcaa
     7861 gtttaccttg atgcagatat tgcagctgga ggctttgtaa caattgaatt gttcgagaat
     7921 aatcacactc caatggaaat tacagcttcc cttgaaaaaa tagaagatgg tcgctatcaa
     7981 gtgttattca gcgaaccttt acctcgaact caaactcgac tgaaaattag ctttaaaaat
     8041 gctaaaatct acgcaatcga aggaaattta gatattttca gaattgaatc agacaatgct
     8101 ctattgaggg ggtaagatta tgaaatatga tttatatgat aattgtattg aacttctaaa
     8161 agaacgcgaa gttacaattg aagatatggc agcgttagta atattttcac aacaaaaata
     8221 ttaccctgaa ttaactcttg acgacgcttc atatgcaatt caacgtgtac taaaaaaacg
     8281 tgaagttcag aatgtaatta tgacaggaat tgagttagat aagttagctg aagcacaaaa
     8341 actatctcca gaatttcaaa agattatgga gaaagataat ccattgtatg ggattgatga
     8401 agtaatcgtc ttatcgatat tgaatttata tggttctatt gcctttacaa attatggcta
     8461 tttagataaa ttaaaaccac tgattttaga aagattgaat gagaatcacg aaggtgtttg
     8521 taatgtattt ctagatgata ttgttggtgc aatagccgca gcagcatgta gtaaaattgc
     8581 acacaatcat gctagtgatg aaatataact attgaattta gtatcgtaaa taataaagcg
     8641 tttggtttct agattattgt cattcaaatt ggataatgat aaatctagaa accaaatata
     8701 ttttccgcat aaaatgaggg attatatatc tcactttttt acaattgtat agtggattaa
     8761 aactagaata gtgcatctct acttctaaaa cattgttaga aatcgatttg actgtcctga
     8821 ttgatttgta ctgttcttat ttcattttac tataatttag tgtgagtaaa atataataat
     8881 aaaggagtta aaacaatgac agtaattaat aaatttgttt taatggagca agcaaaaaaa
     8941 gttttaaaaa atgcttactg tccgtattcc aaatttcctg taggtgcagc aattttattt
     9001 aaagatggta aagtaattac aggagcaaat atagaaaatg tatcgtttgg tgtaactaac
     9061 tgtgcagaac gtagtgctat tttttatggg gcttctcaag gatatagaaa aggagatatt
     9121 cttgcgattg ctgttgcagg tgaaactgaa gactacttac caccatgcaa catttgtcgt
     9181 caagttatgg tagaattttg tgagcctgat accttagtct ttctattaaa tggtaaggga
     9241 aacatacttg aattgcgatt agaggaatta gtcccatatt cgttctcaag tctagaaatg
     9301 taattacgta gtatgaaata aggagaaaaa aacaatgtca gatttgaaaa aatacgaagg
     9361 tgtcattcca gccttctacg catgttatga tgatcaagga gaagtaagcc cagaacgtac
     9421 gcgtgcct
//
LOCUS       DAVHBD010000057         9260 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000057 DAVHBD010000000
VERSION     DAVHBD010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9260
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.057"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..71
                     /locus_tag="VVK04_001868"
     CDS             <1..71
                     /locus_tag="VVK04_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU3990492.1"
                     /translation="IPAMSTPVFDNIEAAIKEHGLS"
     gene            119..1594
                     /locus_tag="VVK04_001869"
     CDS             119..1594
                     /locus_tag="VVK04_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU3990493.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1620..1697
                     /locus_tag="VVK04_001870"
                     /pseudo
     CDS             1620..1697
                     /locus_tag="VVK04_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            1899..8600
                     /locus_tag="VVK04_001871"
     CDS             1899..8600
                     /locus_tag="VVK04_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU3990494.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIANTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTTGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDYSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSFPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKIEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(8848..>9260)
                     /locus_tag="VVK04_001872"
     CDS             complement(8848..>9260)
                     /locus_tag="VVK04_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990495.1"
                     /translation="SAKNLANWHYNDKEDSYIHPDGWCYRFHHIKYQKTQTDFQQEIK
                     VYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQDRQIFAQRKIDVKPVFGQIKAC
                     LGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
BASE COUNT         2922 a         1809 c         2029 g         2500 t
ORIGIN      
        1 gtatcccagc aatgagcact ccagtatttg acaatattga agcagctatt aaagaacacg
       61 gattaagcta attctaattt gttaacattc atataacata aaaaagggag gaactgttat
      121 ggatgcaatc tttgacctaa tcggaaaggt tttcaatccc atcttagaaa tgggtggacc
      181 tgtcatcatg ttaatcattt tgacagtatt ggctttactt tttggagtga aattctccaa
      241 agcgcttgaa ggtggtatca aacttgccat cgctcttaca ggtatcggtg ctatcatcgg
      301 tatgctaaat ggtgctttct cagcatcact agcaaaattc gttgaaaaca ctggtatcca
      361 attgagtatt accgacgttg gttgggcacc acttgctaca atcacttggg gttctgcttg
      421 gacactatac ttcttgctca tcatgttgat tgtcaacata gtgatgctag ctatgaagaa
      481 aacagataca cttgacgttg atatctttga tatctggcac ttgtctatca caggtctctt
      541 gattaaatgg tatgctgata acaatggtgt gagccaagga gtttcactct ttattgctac
      601 agcagctatc gtccttgtcg gtgtgttgaa aattatcaac tctgacttga tgaaacctac
      661 atttgatgac cttcttaacg ccccaagttc atcaccaatg acatcaactc acatgaacta
      721 catgatgaac ccagttatca tggttttgga taagattttt gaaaaattct tcccaggcct
      781 tgataaatat gactttgatg ctgctaaatt gaacaagaaa atcggtttct ggggatctaa
      841 attcttcatc ggtttcatcc ttggtatcgt tatcggtatt atgggaactc cacatccaat
      901 tgcaggtgtt gcagatgcag ataaatggcg tcttgttatc aaaggatggt tgtctcttgg
      961 tttgactgcc ggtgtatctt tggaactctt ctcacttatc ggttcatggt tcatcgcagc
     1021 cgtagaacca ctatcacaag gtattacaaa cgttgctact aaacgtcttc aaggacgtaa
     1081 attcaatatc ggtcttgact ggccattcat cgctggtcgt gctgaaatct gggcttgtgc
     1141 caacgtactt gcaccaatca tgttgattga agcagtgctt ctttcaaaag ttggaaatgg
     1201 tatcttgcca cttgcaggta tcatcgctat gggtgttact ccagctctct tggttgtaac
     1261 tcgtggtaaa ttgctccgta tgattatctt cggaacactc ttgttgccac tcttccttct
     1321 ttcaggtaca cttattgcac catttgcaac agaacttgct aaaggtgtag gtgccttccc
     1381 agaaggtgtg agccaaactc aattgattac tcactctact cttgaaggac caatcgaaaa
     1441 acttcttggt tggacaattg gtaacactac aactggtgat atcaaagcaa tccttggtgc
     1501 agtagccttc cttgtattct atatcggtat ctttgcttgg tacagaaaac aaatgatcaa
     1561 acgtaacgaa gagtacgcag caaaagcaaa ataatgcgct cctataaaat ataaactcaa
     1621 tgaaaatcaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac agttttgagg
     1681 ttgtagataa gactgacgaa gtcggctcaa aacacagttt tgaggttgta gatgaaactg
     1741 acgaagtcag taatcatatc tacggcaagg cgacgctgac gaagtttgaa ttggattttc
     1801 gcagagtgta aattgttgaa actaggttgt cataccatgt ataccacttg ggctttggta
     1861 gtagctaact gcactaaata taatataagg agggttttat ggggaaaggc cattggaatc
     1921 ggaaaagagt ttatagcatt cgtaagtttg ctgtgggagc ttgctcagta atgattggga
     1981 cttgtgcagt tctattagga ggaaatatag ctggagaatc tgtagtttat gcggatgaaa
     2041 cacttattac tcatactgct gagaaaccta aagaggaaaa aatgatagta gaagaaaagg
     2101 ctgataaagc tttggaaact aaaaatgtag ttgaaaggac agaacaaagt gaacctagtt
     2161 caactgaggc tattgcatct gagaagaaag aagatgaagc cgtaactcca aaagaggaaa
     2221 aagtgtctgc taaactggaa gaaaaagctc caaggataga atcacaagct tcaagtcaag
     2281 aaaaaccgct caaggaagat gctaaagctg taacaaatga agaaatgaat caaatgattg
     2341 aagacaggaa agtggatttt aatcaaaatt ggtactttaa actcaatgca aattctaagg
     2401 aagccattaa acctgatgta gacgtatcta cgtggaaaaa attagattta ccgtatgact
     2461 ggagtatctt taacgatttc gatcatgaat ctcctgcaca aaatgaaggt ggacagctca
     2521 acggtgggga agcttggtat cgcaagactt tcaaactaga tgaaaaagac ctcaagaaaa
     2581 atgttcgcct tacttttgat ggcgtctaca tggattctca agtttatgtc aatggtcagt
     2641 tagtggggca ttatccaaat ggttataacc agttctcata tgatatcacc aaataccttc
     2701 acaaagatgg tcgtgagaat gtgattgctg tccatgcagt caacaaacag ccaagtagcc
     2761 gttggtattc aggaagtggt atctatcgtg atgtgacttt acaagtgaca gataaggtgc
     2821 atgttgagaa aaatgggaca actattttaa caccaaaact tgaagaacaa caacatggca
     2881 aggttgaaac tcatgtgacc agcaaaatcg ccaatacgga cgacaaagac catgaacttg
     2941 tagccgaata tcaaatcgtt gaacgaggtg gtcatgctgt aacaggctta gttcgtacag
     3001 cgagtcgtac cttaaaagca catgaatcaa caagcctaga tgcgatttta gaagttgaaa
     3061 gaccaaaact ctggaccgtt ttaaatgaca aacctgcctt gtacgaattg attacgcgtg
     3121 tttaccgtga cggtcaattg gttgatgcta agaaggattt gtttggttac cgttactatc
     3181 actggactcc aaatgaaggt ttctctttga atggtgaacg tattaaattc catggagtat
     3241 ccttgcacca cgaccatggg gcgcttggag cagaagaaaa ctataaagca gaatatcgcc
     3301 gtctcaaaca aatgaaggag atgggagtta actccatccg tacaacccac aaccctgcta
     3361 gtgagcaaac cttgcaaatc gcagcagaac taggtttact cgttcaggaa gaggcttttg
     3421 atacttggta tggtggcaag aaaccttatg actatggacg tttctttgaa aaagatgcca
     3481 ctcacccaga agctcgaaaa ggtgaaaaat ggtctgattt tgacctacgt accatggtcg
     3541 aaagaggcaa aaacaaccct gctatcttca tgtggtcaat tggtaatgaa ataggtgaag
     3601 ctaatggtga tgcccactct ttagtaactg ttaaacgttt ggtcaaggtt atcaaggatg
     3661 ttgataagac tcgctatgtt accatgggag cagataaatt ccgtttcggt aatggtagcg
     3721 gagggcatga gaaaattgct gatgaactcg atgctgttgg atttaactat tctgaagata
     3781 attacaaagc ccttagagct aagcatccaa aatggttgat ttatggatca gaaacatctt
     3841 cagctacccg tacacgtgga agttactatc gccctgaacg tgaattgaaa catagcaatg
     3901 gacctgagcg taattatgaa cagtctgact atgggaatga tcgtgttggt tgggggaaaa
     3961 cagcaaccgc ttcatggact tttgaccgtg acaacgctgg ctatgctgga cagtttatct
     4021 ggacaggtac ggactatatt ggtgaaccta caccatggca caaccaaaat caaactcctg
     4081 ttaagagctc ttactttggt atcgtagata cagccggcat tccaaaacat gacttctacc
     4141 tctaccaaag ccaatgggtt tctgttaaga agaaaccgat ggtacacctt cttcctcact
     4201 ggaactggga aaacaaagaa ttagcatcca aagtagctga ctcagaaggt aagattccag
     4261 ttcgtgctta ttcgaatgct tctagtgtag aattgttctt gaatggaaaa tctcttggtc
     4321 ttaagacttt caataaaaaa caaaccagcg atgggcggac ttaccaagaa ggtgcaaatg
     4381 ctaatgaact ttatcttgaa tggaaagttg cctatcaacc gggtaccttg gaagcaattg
     4441 ctcgtgatga atctggcaag gaaattgctc gagataagat tacgactact ggtaagccag
     4501 cggcagttcg tcttattaag gaagaccatg cgattgcagc agatggaaaa gacttgactt
     4561 acatctacta tgaaattgtt gacagccagg ggaatgtggt tccaactgct aataatctgg
     4621 ttcgcttcca attgcatggc caaggtcaac tggtcggtgt agataacgga gaacaagcca
     4681 gccgtgaacg ctataaggcg caagcagatg gttcttggat tcgtaaagca tttaatggta
     4741 aaggtgttgc cattgtcaaa tcaactgaac aagcagggaa attcaccctt actgcccact
     4801 ctgatctctt gaaatcgaac caagtcactg tctttactgg taagaaagaa ggacaagaga
     4861 agactgtttt ggggacagaa gtgccaaaag tacagaccat tattggagag gcacctgaaa
     4921 tgcctaccac tgttccgttt gtatacagtg atggtagccg tgcagaacgt cctgtaacct
     4981 ggtcttcagt agatgtgagc aagcctggta ttgtaacggt gaaaggtatg gctgacggac
     5041 gagaagtaga agctcgtgta gaagtgattg ctcttaaatc agagctacca gttgtgaaac
     5101 gtattgctcc aaatactgac ttgaattctg tagacaaatc tgtttcctat gttttgactg
     5161 atggaagtgt acaagagtat gaagtggaca agtgggagat tgccgaagaa gataaagcta
     5221 agttagcaat tccaggttct cgtattcaag cgaccggtta tttagaaggt caaccaattc
     5281 atgcaaccct tgtggtagaa gaaggcaatc ctgcagcacc tgtagtgcca actgttactg
     5341 ttggaggtga agcagtaaca ggtcttacta gtcgacaacc aatgcaatat cgtactctat
     5401 cttatggtgc ccaattgcca gaagtcacag caagtgctaa aaatgcagct gttacagttc
     5461 ttcaagcaag cgcagcaaac ggcatgcgtg cgagcatctt tattcagcct aaagatggtg
     5521 gccctcttca aacctatgca attcaattcc ttgaagaagc gccaaaaatt gctcacttga
     5581 gcttgcaagt ggaaaaagct gacagtctca aagaagacca aactgtcaaa ttgtcggttc
     5641 gagctcacta tcaagatgga acgcaagctg tattaccagc tgataaagta accttctcta
     5701 caagtggtga aggggaagtc gcaattcgta aaggaatgct tgagttgcat aagccaggag
     5761 cagtcactct gaacgctgaa tatgagggag ctaaaggcca agttgaactc actatccaag
     5821 ccaatactga gaagaagatt gcgcaatcca tccgtcctgt aaatgtagtg acagatttgc
     5881 atcaggaacc aagtcttcca gcaacagtaa cagttgagta tgacaaaggt ttccctaaaa
     5941 ctcataaagt cacttggcaa gctattccga aagaaaaact agactcctat caaacatttg
     6001 aagtactagg taaagttgaa ggaattgacc ttgaagcgcg tgcaaaagtc tctgtagaag
     6061 gtatcgtttc agttgaagaa gtcagtgtga caactccaat cgcagaagca ccacaattac
     6121 cagaaagtgt tcggacatat gattcaaatg gtcacgtttc atcagctaag gttgcatggg
     6181 atgcgattcg tccagagcaa tacgctaagg aaggtgtctt tacagttaat ggtcgcttag
     6241 aaggtactca attaacaact aaacttcatg ttcgcgtatc tgctcaaact gagcaaggtg
     6301 caaacatttc tgaccaatgg accggttcag aattgccact tgcctttgct tcagactcaa
     6361 atccaagcga cccagtttca aatgttaatg acaagctcat ttcctacaat aaccaaccag
     6421 ccaatcgttg gacaaactgg aatcgtacta atccagaagc ttcagtcggt gtcctattcg
     6481 gagattcagg tattttgagc aaacgctccg ttgataatct aagtgtcgga ttccatgaag
     6541 accatggagt tggtgcaccg aagtcttatg tgattgagta ttatgttggt aagactgtcc
     6601 caacagctcc taaaaaccct agttttgttg gtaatgagga ccatgtcttt aatgattctg
     6661 ccaactggaa accagttact aatctaaaag cccctgctca actcaaggct ggagaaatga
     6721 accactttag ctttgataaa gttgaaacct atgctgttcg tattcgcatg gttaaagcag
     6781 ataacaagcg tggaacgtct atcacagagg tacaaatctt tgcgaaacaa gttgcggcag
     6841 ccaagcaagg acaaacaaga atccaagttg acggcaaaga cttagcaaac ttcaaccctg
     6901 atttgacaga ctactacctt gagtctgtag atggaaaagt tccggcagtc acagcaagtg
     6961 ttagcaacaa tggtctcgct accgtcgttc caagcgttcg tgaaggtgag ccagttcgtg
     7021 tcatcgcgaa agctgaaaat ggcgacatct taggagaata ccgtctgcac ttcactaagg
     7081 ataagagctt actttctcat aaaccagttg ctgcggttaa acaagctcgc ttgctacaag
     7141 taggtcaagc acttgaattg ccgactaagg ttccagttta cttcacaggt aaagacggct
     7201 acgaaacaaa agacctgaca gttgaatggg aagaagttcc agcggaaaat ctgacaaaag
     7261 caggtcaatt tactgttcga ggccgtgtcc ttggtagtaa ccttgttgct gaggtcactg
     7321 tacgagtgac agacaaactt ggtgagactc tttcagataa ccctaactat gatgaaaaca
     7381 gtaaccaggc ctttgcttca gcaaccaatg atattgacaa aaactctcat gaccgcgttg
     7441 actatctcaa tgacggagat tattcagaaa atcgtcgttg gacaaactgg tcaccaacac
     7501 catcttctaa tccagaagta tcagcgggtg tgattttccg tgaaaatggt aagattgtag
     7561 aacggactgt tgcacaagga aaagttcagt tctttgcaga tagtggtacg gatgcaccat
     7621 ctaaactcgt tttagaacgc tatgtcggtc cagagtttga agtgccaacc tactattcaa
     7681 actaccaagc ctacgacgca gaccatccat tcaacaatcc agaaaattgg gaagctgttc
     7741 cttatcgtgc ggataaagac attgcagctg gtgatgaaat caacgtaaca tttaaagcta
     7801 tcaaagccaa agctatgaga tggcgtatgg agcgtaaagc agataagagc ggtgttgcga
     7861 tgattgagat gaccttcctt gcaccaagtg aattgcctca agaaagcact caatcaaaga
     7921 ttcttgtaga tggaaaagaa cttgctgatt tcgctgaaaa tcgtcaagac tatcaaatta
     7981 cctataaagg tcaacggcca aaagtctcag ttgaagaaaa caatcaagta gcttcaactg
     8041 tggtagatag tggagaagat agctttccag tacttgttcg cctcgtttca gaaagtggaa
     8101 aacaagtcaa ggaataccgt atccacttga ctaaggaaaa accagtttct gagaagacag
     8161 ttgctgctgt acaagaagat cttccaaaaa tcgaatttgt tgaaaaagat ttggcataca
     8221 agacagttga gaaaaaagat tcaacactgt atctaggtga aactcgtgta gaacaagaag
     8281 gaaaagttgg aaaagaacgt atctttacag cgattaatcc tgatggaagt aaggaagaaa
     8341 aactccgtga agtggtagaa gttccgacag accgcatcgt cttggttgga accaaaccag
     8401 tagctcaaga agctaaaaaa ccacaagtgt cagaaaaagc agatacaaaa ccaattgatt
     8461 caagtgaagc tagtcaaact aataaagccc agttaccaaa tacaggtagt gcggcaagcc
     8521 aagcagcagt agcagcaggt ttagctcttc taggtttgag tgcaggatta gtagttacta
     8581 aaggtaaaaa agaagactag aaattttgat accttcttta tcattaaaga ccaaagaaaa
     8641 actcttgtcc taaatagaag ataaagagtc tggaacaaaa tagttctcaa ccacaaaaaa
     8701 gctagatatt tccaattgcg gaactctagc tttttaattt tgagtcgttc tcttattgta
     8761 tagtagattg aaactagagt agtacacttc tacttctaaa acattgttag aaatcgattt
     8821 gactgtcctt atcgatttgt cctgttctta tttcatttca ctatgtttta ggaggttatt
     8881 ggccataagt accaatccca tgtcaattct cacttgacgc ttgcctctca gattacatct
     8941 cttgtaaccc aaacaagcct ttatctgccc aaagacaggt ttcacatcaa tcttgcgttg
     9001 agcgaaaatc tgtctatctt ggggagataa aagcgcctga cattctttag ctttcaagtt
     9061 ttgatagcgt tcgttcatat acaatccctt ttgaggggct gattcaggtt catcagcgta
     9121 gtaaaccttg atttcctgtt gaaagtctgt ctgtgttttc tggtacttga tatggtgaaa
     9181 acgatagcac cagccatcag gatgtatgta gctatcctcc ttgtcattat agtgccaatt
     9241 cgctaagttt ttagctgact
//
LOCUS       DAVHBD010000058         9173 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000058 DAVHBD010000000
VERSION     DAVHBD010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.058"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(1..200)
                     /locus_tag="VVK04_001873"
                     /pseudo
     CDS             complement(1..200)
                     /locus_tag="VVK04_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(246..479)
                     /locus_tag="VVK04_001874"
     CDS             complement(246..479)
                     /locus_tag="VVK04_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU3990496.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(485..1477)
                     /gene="plsX"
                     /locus_tag="VVK04_001875"
     CDS             complement(485..1477)
                     /gene="plsX"
                     /locus_tag="VVK04_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU3990497.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1474..2244)
                     /gene="recO"
                     /locus_tag="VVK04_001876"
     CDS             complement(1474..2244)
                     /gene="recO"
                     /locus_tag="VVK04_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU3990498.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2241..3410)
                     /locus_tag="VVK04_001877"
     CDS             complement(2241..3410)
                     /locus_tag="VVK04_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU3990499.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKVVILNYPANPTGITYSREQLETLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3559..4569
                     /locus_tag="VVK04_001878"
     CDS             3559..4569
                     /locus_tag="VVK04_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU3990500.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILHFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(4727..4807)
                     /locus_tag="VVK04_001879"
                     /pseudo
     CDS             complement(4727..4807)
                     /locus_tag="VVK04_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4842..5279)
                     /locus_tag="VVK04_001880"
     CDS             complement(4842..5279)
                     /locus_tag="VVK04_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU3990501.1"
                     /translation="MSQEFINPSDGVIHQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARDYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5364..7997)
                     /gene="polA"
                     /locus_tag="VVK04_001881"
     CDS             complement(5364..7997)
                     /gene="polA"
                     /locus_tag="VVK04_001881"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU3990502.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYLQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            8248..8598
                     /locus_tag="VVK04_001882"
     CDS             8248..8598
                     /locus_tag="VVK04_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU3990503.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            8813..8929
                     /locus_tag="VVK04_001883"
     CDS             8813..8929
                     /locus_tag="VVK04_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU3990504.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            8922..9155
                     /locus_tag="VVK04_001884"
     CDS             8922..9155
                     /locus_tag="VVK04_001884"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990505.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         2571 a         2285 c         1717 g         2600 t
ORIGIN      
        1 attttaaacg tttttacttt ggcaaagata ttctcaacct tgcttctctc cttagatagc
       61 gcatgattac aggctttatc ttcaactgtt agcggcttga gtttgctgga tttacgtgga
      121 gtttgtgctt gaggatatat cttcatgagc ccttgataac cactgtcagc caagattttt
      181 ccagcttgtc cgatatttct catttctaaa aaccatctac ttccgttgac ttggaactcc
      241 gattgctatt ttccttgaat gattttaacc acatctccta cgttttggag ttggtcaatt
      301 tcttcatcgc tgatttcgat actaaattca tcttccagag tcaagataaa ctccatcaag
      361 tcaacagaat ccgcatccaa atcgtctttc agactcaagg attctgtcac gacaaagtcc
      421 tctccctgtc gctcttggat aatggtcaca atacggtcaa aaatttcttt ttctgtcatc
      481 tcttttattc tcctgaaaat tcacgcgcag tctgggcaac tacgtctgtt tctagcatgg
      541 tacgaatctg gcgaatcgta ctataaacag ccttggcatc gcttgagcca tgagtcttga
      601 caacaggtgc cttaacacca aacaagaccg ctccaccaac atctgaataa ttgagctgtt
      661 ttttcaaacc tctgaggctg tccttgagaa ggagggcacc tagtttcgct cgaagaccac
      721 cacctgtaat agctgtcttg agcaagccca tgattcccat agctgtccct tcgatggatt
      781 tgagcacagc gtttcccgtg aaaccatctg ccacaacaac atctgcaacg ccattcatca
      841 aatcacgcgc ttccacattt ccgataaagt tcaaactttc atcagccact agtaattcat
      901 aagtttcctt acgaagcgga tcgcccttgc tactctctgt tccgttattg agcaagccaa
      961 cacgtggttg cgcaatgcca cgaacatttt tagcatagaa ggatcctaga accgcgtatt
     1021 gatggaggtg ctgggctgta ttttccgcat tggcaccgag gtctagcatg tcaaatccct
     1081 tcccatctac agtcggcaaa gtcgacataa gcccaggacg gtcgatattc ttgatacgac
     1141 ccacgatgaa gaatccagca gccaacaagg cacctgtatt cccagccgaa aggacagcgt
     1201 ctgcttcacc atctttgaca gccttggctg ccaataccat actggcattt ttcttattcc
     1261 taatagctct cgtaggttca tcatccgaat caatcttctc atccgtatgg ataatgctga
     1321 cgcgctctgt cgctgtcaga tattgcttga ttttagcttc atctccgtaa agttgaacct
     1381 cgatatctga aaagtcagat agggcttgat tgacaccctc aacaatggcc tgaggtgcgt
     1441 aatcgccccc catggcatct actgcgattt ttttcatttc ttttcctctt ttagtaattg
     1501 tccccagtct gctagggaat caataaattt ctttgatttt aggtgaatcc caacgtactc
     1561 ttcatataat tgatccataa attggcgtag ctcttgcttg attccaggct tgagcgaaat
     1621 ggtctccaaa gtctcaaaat caatagcttg aaattgattg agcagatagg ggatattggg
     1681 attgagatga caacgtctct tatcctcatg ataatgctct ggacagaggc aggctccata
     1741 tttgaaagaa aagtcaaaag cctgaccaac ccgatggcag aagacacact cattaaaatt
     1801 gaggctgatt ccaaatcgag tcaaaatttg aatttcaaaa atattggtca aaacctgata
     1861 atccaagcct gcttccatca actccaaagt cttttgcaaa aaagcaaaca agggagcatc
     1921 ctgctgattg tcctgcaaac tagcatctgc aagagctgcc acataggtcg cataggccat
     1981 gacaaagagg tcactattaa tcttgggaaa agtcatgacc tcatgatagt cttcgatgta
     2041 actgagtccg tcatcattga ttcgcaagag aaatcgtgcc agcaccaagg gctgaataac
     2101 aggcgccagc ttagactgac cagcgtgttt gacaaaaaac atgcgtttgc caacctgctc
     2161 tgtaaaaatt ttgacgagct tgtcatcctc acgaaaattg cgattgtaaa gcaccaagcc
     2221 ttgactcgtg atagactgaa tcatgcttct ctcatgtact cctcaagtcg tttcatggct
     2281 tctttgatag tctccatgct ggctgcataa gataggcgga cgtagccttc cccgtaacgt
     2341 ccaaaggctg caccagggat aaaggcaacg gccttcttct gagcaaaatc cttcagaaaa
     2401 gcaaaggagt cttgattgta gcccgctgga attttagcaa aaatatagaa ggcaccgtct
     2461 ggtttgataa tctcaaaacc aagagcagtc attttttcga tgatatagtc ccgacgttgg
     2521 atatattcct tcttcatggg ctccgcatcg tttttaccag ccgtcaaggc ttctaccgca
     2581 gcgtgttgcg ccatggtatt tgcggcagtg accaagtact ggtgactctt gattaactgg
     2641 gctgtgaagg tcgcaggagc gaaaatcagc cccaaacgcc aacctgtcat ggcatgcgat
     2701 ttagacaaac cattgataat aatagcctgg tctctcaaca tcgttcctag agacacatgg
     2761 gcttcgcctg tgtaggtcaa ttctgagtaa acctcatcac agacaacaaa aatttcatac
     2821 ttgcgtaaaa cagctgccaa ggtctctaac tgctctcgac tgtaggtaat tcctgtcgga
     2881 ttggctggat agttgagaat aaccaccttg agcttatcac cctgctccaa aatggccttc
     2941 tccaacatct caggagtcaa gacaaaacca ttttcagtcg tatcaatctc aacaatttct
     3001 gccccaacta agttaacaat cggttcatag cctggataag caggagctgg caaaagtacc
     3061 ttgtctccct cttccaaaat agccgtcaaa gtcgcagata aagcctctgt cgccccaatt
     3121 gtaaccaaga tttcattttc aggagcatag tccagttggt acttttcctt aacaaagtca
     3181 ctagctgcct gacgtagagt cagcagacca ctcatccctg tatagtagga ttggttctga
     3241 tcaatcgctc gcttggccgc ctccttgaca tggtctggcg ttgtaaaatc aggttccccc
     3301 aaggtcaaac gcaagacccc aggaatctcc gaaatagcct ggtcaaactg acgaatcaac
     3361 gaaacttgaa ttttatctaa ctgtttatta aagcgcttag ttaagtccat agatacctcc
     3421 tactttcaaa acgtatctct attatactac aaaagcctcc cgaccgcaaa aatacattag
     3481 agaatagctt tccactttct attttacttt tcctctttac aggtctataa tggtaacaga
     3541 ttctatttgg aggtttttat gtcatttcta tcaaaaaatg gagcaggcat cttggtctgc
     3601 cttctcattt ctatcgtatc ttggtactta ggaggattct tccctgtgat tggcgcaccc
     3661 gtttttgcga tttttatggg catgctccta catccctttc tctcgtctta taaacaactg
     3721 gatgctggat tgacctttag ttccaagaaa ttgctccagt atgccgttat cttgcttggt
     3781 tttggtctca atatctctca agtcttcgca gttgggcaat cttcactccc tgtcatcctt
     3841 tccaccattt caatagcctt gattgttgcc tacctcttcc agcgcttctt tgccctggat
     3901 acaaaactgg ctaccttgat tggagtaggt tcttctatct gtgggggttc tgccattgca
     3961 gcgacagcgc ctgttatcca tgctaaggaa aaggaagtag cccaagccat ctccgttatc
     4021 tttttcttca atgtcttggc tgcgctcatc tttccaaccc tcggcacctg gcttcatcta
     4081 tccaatgacg gcttcgccct ctttgcagga actgcggtca atgatacttc ctctgtaacc
     4141 gccacagcta gcgcttggga cagtctctac cagaccaata ccctcgaatc cgcaaccatt
     4201 gtcaaactca cgcgaaccct agctatcatc cccatcactc tctttctctc ctactggcaa
     4261 agtcgcgagc aaaaaaataa gcaaggctta caactgaaaa aagtcttccc actttttatc
     4321 cttcacttca tccttgcatc gctcctaacc acccttctga cctctctcgg tgtgtctagt
     4381 agtttcttta cccctctcaa acaactctct aaattcctca ttatcatggc catgagtgcc
     4441 atcggtctca aaactaatct ggtcgctatg gtcaaatcca gtggaaaatc cattgttctc
     4501 ggagccgtct gctggattgc catcatcctc accagccttg gtatgcagac ccttatcggc
     4561 attttctaat actcttcgaa aatctcttca aaccacgtca acgtcgcctt gccgtatata
     4621 tgttactgac ttcgtcagtt ctatctgcaa cctcaaaacg gtgttttgag ctgacttcgt
     4681 cagttctatc tgcaacctca aaacggtgtt ttgagctgac ttcgtcagtc gtatctacaa
     4741 cctcaaaaca gtgttttgag caacccgcag ctagtttcct agtttgctct ttgattttca
     4801 ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc ctcaatcaag
     4861 cgagtatgtt ctctcttgat acagcgattc atcacgatat catcacatcc accatcacgc
     4921 aaaatctctt tcgcttctaa actttcaagt cctagctgtg cccaaaaaat cttggcatca
     4981 gctttgagaa aatcacgcgc cacatcgggc agaaattcac tgcgacgata aacattgaca
     5041 atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc caagatttcg
     5101 ccacctgccg ccttgggatt gactgggatg attttatagt cccgagcctg catttccttt
     5161 gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc aagggtttta
     5221 ctcgttgcga gatactgatg aatcacgcca tcacttggat tgataaattc ttgactcata
     5281 gaaattctcc tttttcatca gtatagcaca ttttgaaaag gtttgcagaa ttctactaca
     5341 aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc ttcattctca
     5401 tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt caccaatttt
     5461 ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg cacttgtaac
     5521 agcatcttgg tctgataacc acctgcaacc aaggctttat ccagctgaat catggcaatc
     5581 ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg ctccgcaaaa
     5641 ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg cttaaagagg
     5701 gtctctacat agctcttatc acgcgcctcc cgcaccactt catccatgta gtttttaata
     5761 cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg actaattccc
     5821 aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt aactgccttg
     5881 gcattgcgac gatcatttgc agtcacatta tcaggacgct caatgccaaa gacccgcatg
     5941 gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg ctcatcctta
     6001 gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag tagcacacta
     6061 tcctcccact ctggcacaaa agccttccga atcaagcgcc cctgttccaa tcgggcagga
     6121 atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa atcctgcaaa
     6181 tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat tacataagta
     6241 gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg agcaatagga
     6301 gcgagacgct ccaaaacatc cactgctgtc gaataacctg tcttggtttt cttagtgtat
     6361 tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg cgagttgaca
     6421 ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat gacaagctca
     6481 ttttcagcct gcatctcaag caaggtctct ttcttgacca taatcccagc aatttccatc
     6541 ttggcaagga caaaagccag aggttgctcc atatcataaa gaagctctaa ttgcccattt
     6601 tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag tttacaagct
     6661 aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt accgtagaaa
     6721 gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc aatttcattg
     6781 tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg cgcctgcaaa
     6841 tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac tctcagagat
     6901 gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt gtctgtggca
     6961 tagagcttat ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg gtaattctca
     7021 ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact gatttggtca
     7081 acaatagtaa aatccaaact ctcagacaca tcagctgacg acacatttaa agcctgcttg
     7141 agctgtttga agcccatctc atcgtagaat ttcccaagat tttcaacatc tggaccacta
     7201 tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt cgctagtgtt
     7261 ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt agaagtcttc
     7321 attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa gagcttaata
     7381 cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc acccatgagc
     7441 gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag gtaatctggc
     7501 gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt atgctcatcc
     7561 gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc atcctgctct
     7621 gctagcttat ccagcgtccc aatgatgtca tccgcctcat actgagccag ctcatagtga
     7681 cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg aaactcatca
     7741 ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa ggtcgtcttt
     7801 cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa atgactcaac
     7861 atcaactgaa aaccataaat cgcattggta tgcaaaccag ccgcattctt aaaacggtcc
     7921 aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc aatcaataat
     7981 aattttttct tatccataca cccattataa aggaaagaat caaaaaatac cattgggaag
     8041 agctagagca agtatttttc aaactttttc cgaataaata gatagagcca gagaatttag
     8101 taaacctaga tttaaaaatg tgctataata tattgaatct ataatagtac accttgactg
     8161 ctaaaatatt tctataaatt aatttgactt tcctgataga gttattcaca tcttatttca
     8221 actcactata gaaggaggaa taggaggatt ctcagacatc cgggcatcag cccaactaat
     8281 gatttgattg ctaagaaaat attcagcaat ccagaaatca cttgtcaatt tattcgcgat
     8341 atgctggact tgccagcaaa aaatgtgacc attttggagg gaagcgatat tcacgtatta
     8401 ctctccatgc cttactcggt gcaggatttt tataccagta tagacgtctt ggcggagttg
     8461 gataacggta ctcaagtaat tattgagatt caagtccatc atcagaattt tttcatcaat
     8521 cacttgtgga cttacctgtg cagtcaggtt aatcaaaatc ttgaaaaaat tcgtcagcga
     8581 gaaggtgata ctcactagag ctacaaacac atcgctcctg tttacgccat tgctatcgtg
     8641 gatagtaatt atttctcaga tgacctggct tttcatagct ttagtatgcg cgaagacaca
     8701 acaggtgagg tattggcgat taccaacaat ggacaggaaa accatctggt taagatggca
     8761 ttcttggaat taaaaaatac agagaaacca gcaaggacga ggttcgcaag ccatggttgg
     8821 agtttttcgg caacaagccc tttacccagc aaccgcaacg agccattacc caagcaaatc
     8881 aactgctgga ctacaagagc tggtccgagg aggacaggaa aatgtttagt caactacata
     8941 tgcgagaaga acaagtcttg ttagcacagg actatgcctt ggaaactgct agggctgaag
     9001 gtcttgaaca aggactagag cgtgggaaag ttgaaggaag ggcagaaagg aaactttttg
     9061 ccttcctaga catagtacgc caaggtcttc tgacttctga ggttgccagc cagcaattag
     9121 gtatgtcagt atctgaattt gaggcactgt tgtaaaatgg ctccataata tcc
//
LOCUS       DAVHBD010000059         9138 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000059 DAVHBD010000000
VERSION     DAVHBD010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.059"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(135..1103)
                     /locus_tag="VVK04_001885"
     CDS             complement(135..1103)
                     /locus_tag="VVK04_001885"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU3990506.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1248..2063)
                     /locus_tag="VVK04_001886"
     CDS             complement(1248..2063)
                     /locus_tag="VVK04_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU3990507.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPD
                     STFLNAFESAIVPPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2088..2585)
                     /locus_tag="VVK04_001887"
     CDS             complement(2088..2585)
                     /locus_tag="VVK04_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU3990508.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VVK04_001888"
     CDS             complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VVK04_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU3990509.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4033..4548)
                     /locus_tag="VVK04_001889"
     CDS             complement(4033..4548)
                     /locus_tag="VVK04_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU3990510.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4550..4993)
                     /locus_tag="VVK04_001890"
     CDS             complement(4550..4993)
                     /locus_tag="VVK04_001890"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU3990511.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            complement(5050..5147)
                     /gene="ffs"
                     /locus_tag="VVK04_001891"
     ncRNA           complement(5050..5147)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VVK04_001891"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5180..5647)
                     /locus_tag="VVK04_001892"
     CDS             complement(5180..5647)
                     /locus_tag="VVK04_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU3990512.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK"
     gene            complement(5848..7134)
                     /locus_tag="VVK04_001893"
     CDS             complement(5848..7134)
                     /locus_tag="VVK04_001893"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU3990513.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7365..7601)
                     /locus_tag="VVK04_001894"
     CDS             complement(7365..7601)
                     /locus_tag="VVK04_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU3990514.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7867..8664
                     /locus_tag="VVK04_001895"
                     /pseudo
     CDS             7867..8664
                     /locus_tag="VVK04_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8699..8896)
                     /locus_tag="VVK04_001896"
                     /pseudo
     CDS             complement(8699..8896)
                     /locus_tag="VVK04_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9062..9135)
                     /locus_tag="VVK04_001897"
     tRNA            complement(9062..9135)
                     /locus_tag="VVK04_001897"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9099..9101),aa:Asn,seq:gtt)
BASE COUNT         2935 a         2181 c         1462 g         2560 t
ORIGIN      
        1 tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt
       61 actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat
      121 ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt
      181 tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta
      241 tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct
      301 gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag
      361 acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta
      421 tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata
      481 acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt
      541 ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc
      601 acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc
      661 atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg
      721 gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt
      781 ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca
      841 ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga
      901 ttgtcattta caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat
      961 tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac
     1021 tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac
     1081 agctttaaat cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc
     1141 acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa
     1201 gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac
     1261 tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta
     1321 accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag
     1381 aagtgagttc ccaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt
     1441 cctttatagg ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag
     1501 tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc
     1561 tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa
     1621 gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa
     1681 acaagtggca ataatttcaa gggttcttct accaaaggag gcacaatagc actttcaaag
     1741 gcatttaaaa atgtactatc tgggaaaaga acccccagta aatcatggat ataagtatta
     1801 gcaaaactag acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc
     1861 ttctttggca attcccattt tttcccaata cggaaaagaa aataaagagc cggaatcatg
     1921 taaaagagag ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa
     1981 ccgtccgtat agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata
     2041 aataaaatac tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg
     2101 actgtcatac ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt
     2161 attaggggag actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg
     2221 aagggcaaga agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga
     2281 aaaggttcat tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct
     2341 cttgtcccca tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga
     2401 ccacctgcat tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg
     2461 tgcagacgag agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga
     2521 tttaactgcc catgtagggc aacataagcc tgattggctt gcataaactg ttcaaaatac
     2581 gacacgattc cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta
     2641 agagaatttg tcacggatta tgcaaagacc tttttcaaga cttcctgaat cgttgtcacg
     2701 ccaatgacct gaatttcctt aggaagagtg attcctgtca aggaattctt aggtacataa
     2761 atcttagtaa agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc
     2821 cgaatctctc ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg
     2881 tctttgtagc tcgaagcaat agcaactgca acagccaagt caatcgcagg ttcatccaat
     2941 ttaacaccac cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt
     3001 ttttccaaaa cagccataat caagctagca cggttaaaat caagtcctgt cgtagtacgc
     3061 ttggcatttc caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc
     3121 gtcccttcca tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg
     3181 aaaacttgac tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca
     3241 atctcattag tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga
     3301 cgctcccctt caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc
     3361 aaggttcctt ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc
     3421 aactgcatga gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa
     3481 atctcaggag acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc
     3541 tccacttctg cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca
     3601 atatcaccta agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca
     3661 tagagaactg tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc
     3721 ccaatcccag gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc
     3781 acacggttga attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca
     3841 gctagtttca tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg
     3901 gcaacctcaa cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga
     3961 tatttagggg aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg
     4021 acaaacctct ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc
     4081 atttggcaca aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc
     4141 tcgatactta gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg
     4201 aataggacta ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc
     4261 aaagttttct attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa
     4321 aggaagaccc gtagcacaga ccacatacga agccgtttct aaagctcttg tgactgcaga
     4381 agatacgatt atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg
     4441 ccgtcccatc tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc
     4501 taactcacgg taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg
     4561 tcgatccaaa tccaccagtt cgaacgccac cagctgcatc tccatctgca attaagaaag
     4621 tagcaaaaac agcctggaca atacgttccc caacttcaag aacaacctct tggtctgtga
     4681 tattcttcat ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat
     4741 caatgacccc aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat
     4801 catagaggta gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga
     4861 caatctctcc tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat
     4921 gcgctgtctc acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac
     4981 cacgaatttt cataattttc tcttttctat tatcatttat tctagattat tctatcttat
     5041 ttattcggaa aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat
     5101 tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata tcacattcct
     5161 attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaagtcc tgcatgatag
     5221 ctgcacattc atcttccaaa attcccgttt caacctctac acgatggtta agacgctcat
     5281 ctgtcaagat atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga
     5341 ccacatttgg aatacgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg
     5401 tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta
     5461 tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac
     5521 gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa
     5581 gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat
     5641 aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac
     5701 acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt
     5761 taggatattt gttacaacaa gttaggaggt cttcttgtaa ccgtctatag tatacccgac
     5821 ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg
     5881 ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg
     5941 acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgaactc cggtaatatc
     6001 ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact
     6061 agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaga ttttcacagt
     6121 atccaaaccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg
     6181 acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt
     6241 tgtaccatac tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt
     6301 tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc
     6361 aatcttgctt ggaccgacac cagaaccaat tgtcacacca ccagctacag ggtttgatga
     6421 cgtaacaaat ggataagtac cttggtcgat atctagcata acaccttgtg caccttcaaa
     6481 aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta
     6541 tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc
     6601 tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg
     6661 ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt
     6721 gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc
     6781 ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga
     6841 aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag
     6901 agatttagga tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat
     6961 cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc
     7021 attatcacca ccttggtaac gtgcaatcac ttctgcattc gctgaaagga agtctgtaat
     7081 cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag tcataatctt
     7141 gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat
     7201 atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat
     7261 ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt actatcatct
     7321 ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaac
     7381 ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaaca
     7441 ataaaatcct tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa
     7501 tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta
     7561 tcatagaaat tagccatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct
     7621 tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt
     7681 aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc
     7741 tacctaaatt tcaaaaaatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc
     7801 ctattagaac tataatattt ttatataggt attatggttc tgattttcta gtataaaaaa
     7861 attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg
     7921 gagctcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa
     7981 aagattgctc agaagctaat tgaaaagact tctatgaccg acattgatca tcagttgtct
     8041 atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg
     8101 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc
     8161 gggagatgga gatgagcttt attgctcagg actttgataa actcaatatc ataactgttc
     8221 ttgagagcag aacacaagcc atcatccgaa atcccatgaa tacaaggcta tcaagcgcta
     8281 ctggaagctc attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac
     8341 ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct attccgaaga
     8401 cttgaaacac cactataatc tctatcagct cttgcttttc cacctctttt tcagactttg
     8461 tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc
     8521 aacgccaaac tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt
     8581 tttaggaact ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg
     8641 ctttcttcaa cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc
     8701 aattgaaaca agaacaagac aaaagagact cgtaaaaggt attgcaactt ggtaatacct
     8761 ttttgatatg agcccatgtt ttcttaatag gattgtactc aggtgagtag ggaggaagag
     8821 gtaaaagttc atgcccaaac tcctcgcata aaagttctag cttacccatt ctatggaatc
     8881 ttgcattgtc cataatatag tagattgaaa ctagaatagt acacctctac ttctaaaaca
     8941 ttgttagaat tcgattttac tgtcctgatc gatttgtcct attcttattt cattttacta
     9001 taacacgaaa tagattatta ttacataaca aaaaagaggt ctaaacctct taactaaatt
     9061 actccgccag taggactcga acctacgaca tcatgattaa cagtcatgcg ctactaccaa
     9121 ctgagctatg gcggatta
//
LOCUS       DAVHBD010000060         9091 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000060 DAVHBD010000000
VERSION     DAVHBD010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.060"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(83..1045)
                     /gene="nrdF"
                     /locus_tag="VVK04_001898"
     CDS             complement(83..1045)
                     /gene="nrdF"
                     /locus_tag="VVK04_001898"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU3990515.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKTEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSADD
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(1233..3392)
                     /gene="nrdE"
                     /locus_tag="VVK04_001899"
     CDS             complement(1233..3392)
                     /gene="nrdE"
                     /locus_tag="VVK04_001899"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU3990516.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(3473..3691)
                     /gene="nrdH"
                     /locus_tag="VVK04_001900"
     CDS             complement(3473..3691)
                     /gene="nrdH"
                     /locus_tag="VVK04_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU3990517.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            4042..4305
                     /locus_tag="VVK04_001901"
     CDS             4042..4305
                     /locus_tag="VVK04_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU3990518.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            4311..6044
                     /gene="ptsP"
                     /locus_tag="VVK04_001902"
     CDS             4311..6044
                     /gene="ptsP"
                     /locus_tag="VVK04_001902"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU3990519.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            6299..8749
                     /gene="phtA"
                     /locus_tag="VVK04_001903"
     CDS             6299..8749
                     /gene="phtA"
                     /locus_tag="VVK04_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEU3990520.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            8907..>9091
                     /locus_tag="VVK04_001904"
     CDS             8907..>9091
                     /locus_tag="VVK04_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU3990521.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSK"
BASE COUNT         2888 a         1672 c         1925 g         2606 t
ORIGIN      
        1 cagttgacaa agagcctatt tttgttgggt tataactttg atgtttctag tttacttttt
       61 gatgattgag agtgatggag aattagtcta aaccgtagtt atagtcatcg tcttgcatgg
      121 cttcaacttc gccaagaagg taaccatttc cgacttgaga gaagaagtcg tggttggaag
      181 ttcctgttga aataccgttc attacgattg ggttgacatc atcagctgaa tctgggaaga
      241 gtggatcttg tcccatgttc atgagagctt tattggcatt gtagcgaagg aaggttttaa
      301 cctcttcagt ccaaccaaca ccgtcataaa gactctctgt gtagccttct tcattttcat
      361 aaagagtata gagtaggtcg tacatccatt ctttgagttt ttcttgctct tcttcaggta
      421 attcattgaa accaagttgg aatttgtaac caatgtaggt tccgtgaaca gactcgtcac
      481 gaataatcaa tttaatgatt tctgcaacgt tggcaagttt gttgttaccg agatagtaga
      541 ggggagtgaa gaaaccagag tagaagagga aggtttcgag gaagacgctg gcaactttct
      601 tttcaagtgg gctgccgttt aggtagattt cgttgacaat ctcagccttc ttttgtaggt
      661 aaggattggt attggtccat tcgaaaattt cttcaatctc agtcttagta ttcaaggtag
      721 aaaagattga tgagtaagat ttagcgtgga cagattccat aaattggatg ttattgaaaa
      781 cagcttcctc atgtggtgta cggatgtctg cgcgaagggc ttgaacccca gtttcagatt
      841 gcatagtgtc aagaagggtt aaaccaccaa aaacttttcc gaccaagtct ttctctttgt
      901 tagatagctt tctccagtca tccaagtcgt ttgataaggg aatacgtgta tcgagccaaa
      961 attgctccgt cagtttttcc caagttgatt tgtcgatgac atcttcgatg gcattccagt
     1021 taatggcttt gtagtaagtt tccatttaaa atctctttct gtgtttagta ttgcgaactc
     1081 acaattattt ctactttacc ataattctat aggagtatcg cacaaaaagt cggaagcccg
     1141 acttttaaaa tgttacataa attatgttat gacatagtag atttgatttt atcagtgctg
     1201 cttagggaaa aataatgttt ctatgctaga aactaaatca cacagctttc acattggttg
     1261 gcgccgactt ctccaccgtc atctgtaaag gtacggacgt agtagataga cttgattccc
     1321 ttgttaaagg catagttacg aaggatggac aagtcacgtg tcgtttgttt attttccctc
     1381 ttccattcgt aaaggccttt tggaatgtca ctacgcatga agagggtgag tgaaagtcct
     1441 tgatccacgt gttcagtcgc agcagcgtaa acatcgatga ctttacgcat atccatatcg
     1501 taggcagaag tgtagtaagg aatggtttct gtagacaagc cagcagcagg gtagtagatt
     1561 ttaccaattt tcttctcttg gcgttcttcg atacgttgcg taatcgggtg gatagaagca
     1621 gaaacgtcgt tgatatagct gatagaacca tttggcgcta cagcaaggcg attttggtgg
     1681 taaagaccat cttcttgaac cttgtcgcga agttcagccc aatcagcaac accagggata
     1741 aagacatttt tgaagagttc tttaacacgg tctgatgttg gaacaaattc accagttaca
     1801 tacttgtcaa agtaacttcc gttagcatag tctgattttt caaagttgtg gaaggtaata
     1861 ccacgttcac gcgcaatatt gtttgactct accaaggtcc agtagttcat aagcataaag
     1921 tagatgcttg taaattcaac agactcaggt gaaccatatt caatgagttg ttgggcaagg
     1981 tagctgtgca gtcccatggc accgagacca aaggtgtggg cttggctatt tccatggtca
     2041 atcgttggta cagctacgat atgtgaacta tctgtaacga aagtaagggc acgaaccata
     2101 gcacggatag aacgaccaaa atcaggtgaa gtcatcatgt taaccacgtt ggttgaaccc
     2161 aggttacatg aaacatctgt tcccatttga aggaattctt gagcatcgtt gatcaagctt
     2221 ggttcttgaa cttgaagaat ctcagaacac aagttactca tgataatctt tccatcaaca
     2281 ggatttgcac ggttagccgt atcgatgttg actacataag gatagccaga ctcttgttgc
     2341 aatttagaga tttcagtttc caaatcccgc gccttgattt ttgtcttgcg aatatttgga
     2401 tttgcgacca attcatcgta tttttcagta atgtcgatgt aattgaatgg cacaccgtat
     2461 tctttttcta cagagtaagg gctgaagagg tacatttctt catttttacg agccaattcg
     2521 tagaatttat caggtactac aacaccaagt gatagagtct tgacacgtac tttttcatca
     2581 gcgttttctt tcttagttga aaggaaagcg atgatatctg ggtgaaagac gttgaggtag
     2641 acaacaccgg caccttgacg ttgccccaat tggttggagt aagagaagct gtcttcaaaa
     2701 agcttcataa caggaacgac acctgaagca gctccttcat agcctttgat aggtgcacca
     2761 gcttcacgaa ggttgctgag ggtaattccc acaccaccac caatacgtga aagttgaaga
     2821 gctgagttga tagaacgtcc gatagagttc atatcatccg tcacttggat taggaaacaa
     2881 gataccaact ctccacggcg agcacgtcca gcattcaaga aggaaggagt agcaggttgg
     2941 tagcgttggt ggatgatttc attggcaata tcgattgcaa cagcttcatt cccatcagcg
     3001 aaataaaggg cgttgaagaa gacacggtct tccatatttt caagatagta ttcaccgtca
     3061 ttagtcttta aggcatattg attgtaaaat ttataagctg ccatgaatga cttgaattgg
     3121 aagttttggt ctttgataaa ttgagctaat tcttccaaga actctggacg gtatttcttg
     3181 ataaaggctg tttcgatgta gttgtgttca atgaggtaat tgattttgtc tttgattgaa
     3241 tcaaaaacca tagtgtttgg aactacattt tctttaaaga aagcatccaa ggcttccttg
     3301 tctttatgaa gcatgatttg tccattaaca ggacggttaa tttcgttatt aagacggaag
     3361 taagtcacgt cttcaagatg ttttaatccc ataaaatttc ccttatctaa ttacaaaaga
     3421 aaggcttcta agttagccct aaaagcagtt tcttctggat gatgtactaa gattatgcta
     3481 attgtttcag ttttcctggt tggaaacctg aaaagacttc agttggtgtt tggataacag
     3541 gagctgcgct aaaaccgagc tctttaactt gatcgacgta ctcaggttgc tcatcaagat
     3601 tgatttcacg ataagagaca ttattactgt ccaagaaacg cttggtcatt ttacattgga
     3661 cacaattgtt tttagaataa acggttacca ttgtgtaact cctcttcaaa atttaatact
     3721 atcttagtat atcagaaaat aaaattttgt caatgatttg aactaaatat agtggtgttc
     3781 ttttgttgtt tttatatata aacacaatat atagtgtttg tattgtgaaa tagcaatgat
     3841 tatcctataa attgttttta aagaaactat atcctgtgtt ttgttatcta ggatagaaga
     3901 ttttcagcaa gttatctgaa aggaaattga aggaaaatcc agaaaatgct tgaaaaaaat
     3961 cctagaagat ggtataatac taaattgtaa gggttatcac atataactca aaaaaagaaa
     4021 gaacaaaagg agagtcaaac tatggcttct aaagatttcc acgtagtggc agaaacaggt
     4081 attcacgcac gtccagcaac attgttggta caaactgcta gcaaatttgc ttcagatatc
     4141 actcttgagt acaaaggtaa atcagttaac cttaaatcaa ttatgggtgt tatgagtctt
     4201 ggtgttggcc aaggtgctga cgtaactatc tcagctgaag gtgcagatgc agatgacgct
     4261 atcgctgcaa tctcagaaac aatggaaaaa gaaggattgg cataagggaa atgacagaaa
     4321 tgcttaaagg aatcgcagca tctgacggtg ttgcagttgc aaaagcatat ctactcgttc
     4381 agccggattt gtcatttgag actattacag tcgaagatac aaacgcagaa gaagctcgcc
     4441 ttgatgccgc tctacaggca tcacaagacg agctttctgt tattcgcgag aaagcagtag
     4501 gtacgctcgg tgaagaagca gctcaagttt ttgatgctca cttaatggtt cttgctgacc
     4561 cagaaatgat cagccaaatc aaggaaacta tccgtgcgaa gaaagtgaat gcagaagcag
     4621 gtctgaaaga agttacagat atgtttatca ctatctttga aggcatggaa gacaacccat
     4681 acatgcaaga acgcgcagcg gatatccgcg acgtgacaaa acgtgtattg gcaaaccttc
     4741 ttggtaaaaa attgccaaac ccagcttcta tcaatgaaga agtgattgtg attgcgcatg
     4801 acttgactcc ttcagataca gctcaattgg acaaaaactt tgtaaaagct tttgtaacca
     4861 acattggtgg acgtacaagc cactcagcta tcatggcacg tacacttgaa attgctgctg
     4921 tattaggtac aaacaacatc actgaaatcg ttaaagacgg tgacatcctt gctgttaacg
     4981 ggatcactgg agaagtgatt atcaacccaa cagatgaaca agcggcagaa tttaaagcag
     5041 ctggtgaagc ctatgcgaaa caaaaagctg aatgggcact tttgaaagat gctcaaacag
     5101 tgactgctga cggtaaacac ttcgagttgg ctgccaatat tggtactcca aaagacgttg
     5161 aaggtgttaa caacaacggt gcagaagctg ttggacttta ccgtacagag ttcttgtaca
     5221 tggattctca agacttccca actgaagatg agcagtatga agcatacaag gctgttcttg
     5281 aaggaatgaa cggtaaacct gttgtcgttc gtacaatgga tatcggtgga gataaggaac
     5341 ttccttactt cgatatgcct cacgaaatga acccattcct tggattccgt gctcttcgta
     5401 tctctatctc tgagactgga gatgctatgt tccgcacaca aatccgtgct cttcttcgtg
     5461 cgtctgttca cggtcaattg cgtatcatgt tcccaatggt tgcgctcttg aaagaattcc
     5521 gtgcagcgaa agcagtcttt gatgaagaaa aagcaaacct tcttgctgaa ggtgttgcag
     5581 ttgcggataa cattcaagtt ggtatcatga tcgagattcc tgcagcggct atgcttgcag
     5641 accaatttgc taaagaagtt gacttcttct caattggtac aaacgacttg atccaatata
     5701 caatggcagc agaccgtatg aacgaacaag tttcatacct ttaccaacca tacaacccat
     5761 caatcctacg cttgattaac aatgtgatca aagcagctca cgctgaaggt aaatgggctg
     5821 gtatgtgtgg tgagatggct ggtgaccaac aagctgttcc acttcttgtc ggaatgggct
     5881 tggatgagtt ctctatgtca gcaacatctg tacttcgtac acgcagcttg atgaagaaac
     5941 tcgacacagc taagatggaa gagtacgcaa accgtgccct tacagaatgc tcaacaatgg
     6001 aagaagttct tgaacttcaa aaagaatacg ttaattttga ttaatcgaaa agtccctgca
     6061 actcagttac agggactttt tttgatattt taaaaagaat tttcaagaaa atctttctta
     6121 taaaaagtcc aaccttgaaa aagtagtggt cagaacaaaa aatacttaaa tggttcataa
     6181 aattcttgac aagttggaga tttaggagta aactattaac cagttaagta atagagagga
     6241 gtttctgcaa tttagaaatg aattgcaact agaaatatca aatagaaaga gagtttcgat
     6301 gaaaattaat aagaaatacc ttgttggttc tgcggcagct ttgattttaa gtgtttgttc
     6361 ttacgagttg ggactgtatc aagctagaac ggttaaggaa aataatcgtg tttcctatat
     6421 agatggaaaa caagcgacgc aaaaaacgga gaatttgact cctgatgagg ttagcaagcg
     6481 tgaaggaatc aatgctgagc aaatcgtcat caagataaca gaccaaggct atgtcacttc
     6541 acatggcgac cactatcatt attacaatgg taaggttcct tatgatgcga ttttcagtga
     6601 agaattactc atgaaagatc caaactataa gctaaaagat gaggatattg ttaatgaggt
     6661 caagggtgga tatgttatca aggtagatgg aaaatactat gtttacctta aggatgctgc
     6721 ccacgcggat aacgtccgta caaaagagga aatcaatcga caaaaacaag aacatagtca
     6781 acatcgtgaa ggtgggactc caagaaacga tggtgctgtt gccttggcac gttcgcaagg
     6841 acgctatact acagatgatg gttatatctt taatgcttct gatatcatag aggatactgg
     6901 tgatgcttat atcgttcctc atggagatca ttaccattac attcctaaga atgagttatc
     6961 agctagcgag ttggctgctg cagaagcctt cctatctggt cggggaaatc tgtcaaattc
     7021 aagaacctat cgccgacaaa atagcgataa cacttcaaga acaaactggg taccttctgt
     7081 aagcaatcca ggaactacaa atactaacac aagcaacaac agcaacacta acagtcaagc
     7141 aagtcaaagt aatgacattg atagtctctt gaaacagctc tacaaactgc ctttgagtca
     7201 acgacatgta gaatctgatg gccttgtctt tgatccagca caaatcacaa gtcgaacagc
     7261 tagaggtgtt gcagtgccac acggagatca ttaccacttc atcccttact ctcaaatgtc
     7321 tgaattggaa gaacgaatcg ctcgtattat tccccttcgt tatcgttcaa accattgggt
     7381 accagattca aggccagaac aaccaagtcc acaaccgact ccggaaccta gtccaggccc
     7441 gcaacctgca ccaaatctta aaatagactc aaattcttct ttggttagtc agctggtacg
     7501 aaaagttggg gaaggatatg tattcgaaga aaagggcatc tctcgttatg tctttgcgaa
     7561 agatttacca tctgaaactg ttaaaaatct tgaaagcaag ttatcaaaac aagagagtgt
     7621 ttcacacact ttaactgcta aaaaagaaaa tgttgctcct cgtgaccaag aattttatga
     7681 taaagcatat aatctgttaa ctgaggctca taaagccttg tttgaaaata agggtcgtaa
     7741 ttctgatttc caagccttag acaaattatt agaacgcttg aatgatgaat cgactaataa
     7801 agaaaaattg gtagatgatt tattggcatt cctagcacca attacccatc cagagcgact
     7861 tggcaagcca aattctcaaa ttgagtatac tgaagacgaa gttcgtattg ctcaattagc
     7921 tgataagtat acaacgtcag atggttacat ttttgatgaa catgatataa tcagtgatga
     7981 aggagatgca tatgtaacgc ctcatatggg ccatagtcac tggattggaa aagatagcct
     8041 ttctgataag gaaaaagttg cagctcaagc ctatactaaa gaaaaaggta tcctacctcc
     8101 atctccagac gcagatgtta aagcaaatcc aactggagat agtgcagcag ctatttacaa
     8161 tcgtgtgaaa ggggaaaaac gaattccact cgttcgactt ccatatatgg ttgagcatac
     8221 agttgaggtt aaaaacggta atttgattat tcctcataag gatcattacc ataatattaa
     8281 atttgcttgg tttgatgatc acacatacaa agctccaaat ggctatacct tggaagattt
     8341 gtttgcgacg attaagtact acgtagaaca ccctgacgaa cgtccacatt ctaatgatgg
     8401 atggggcaat gccagtgagc atgtgttagg caagaaagac cacagtgaag atccaaataa
     8461 gaacttcaaa gcggatgaag agccagtaga ggaaacacct gctgagccag aagtccctca
     8521 agtagagact gaaaaagtag aagcccaact caaagaagca gaagttttgc ttgcgaaagt
     8581 aacggattct agtctgaaag ccaatgcaac agaaactcta gctggtttac gaaataattt
     8641 gactcttcaa attatggata acaatagtat catggcagaa gcagaaaaat tacttgcgtt
     8701 gttaaaagga agtaatcctt catctgtaag taaggaaaaa ataaactaat gaaaaatgaa
     8761 agtctcgata aagaggcttt catttttatt atgtatatat gtaaaattct tgacaagcaa
     8821 tattaaaaag agtaaactat taactagtta attaaccggt ttattacttt atagtgaatc
     8881 aaatatactt aagaaaagag gaaagaatga aaattaataa aaaatatcta gcaggttcag
     8941 tggcagtcct tgccctaagt gtttgttcct atgagcttgg acgttaccaa gctggtcagg
     9001 ataagaaaga gtctaatcga gttgcttata tagatggtga tcaggctggt caaaaggcag
     9061 aaaacttgac accagatgaa gtcagtaaga g
//
LOCUS       DAVHBD010000061         8623 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000061 DAVHBD010000000
VERSION     DAVHBD010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8623
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.061"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            184..1203
                     /gene="galE"
                     /locus_tag="VVK04_001905"
     CDS             184..1203
                     /gene="galE"
                     /locus_tag="VVK04_001905"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU3990522.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            1205..2158
                     /locus_tag="VVK04_001906"
     CDS             1205..2158
                     /locus_tag="VVK04_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU3990523.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(2220..2426)
                     /locus_tag="VVK04_001907"
     CDS             complement(2220..2426)
                     /locus_tag="VVK04_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU3990524.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            2478..2954
                     /locus_tag="VVK04_001908"
     CDS             2478..2954
                     /locus_tag="VVK04_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU3990525.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            2963..3634
                     /locus_tag="VVK04_001909"
     CDS             2963..3634
                     /locus_tag="VVK04_001909"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU3990526.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            3765..4103
                     /locus_tag="VVK04_001910"
     CDS             3765..4103
                     /locus_tag="VVK04_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU3990527.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            4106..4735
                     /locus_tag="VVK04_001911"
     CDS             4106..4735
                     /locus_tag="VVK04_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU3990528.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            4975..6126
                     /locus_tag="VVK04_001912"
     CDS             4975..6126
                     /locus_tag="VVK04_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU3990529.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            6439..7188
                     /gene="truA"
                     /locus_tag="VVK04_001913"
     CDS             6439..7188
                     /gene="truA"
                     /locus_tag="VVK04_001913"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU3990530.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHTLGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            7178..7951
                     /locus_tag="VVK04_001914"
     CDS             7178..7951
                     /locus_tag="VVK04_001914"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU3990531.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            7929..8390
                     /locus_tag="VVK04_001915"
     CDS             7929..8390
                     /locus_tag="VVK04_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU3990532.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         2436 a         1611 c         1938 g         2638 t
ORIGIN      
        1 gatagaactg acgaagtcag taaccatacc catggcaagg cgacgttgac gtggtttgaa
       61 ttggattttc gaagagtata agcattttac tgaaatttta tcaggtagtt taggatggca
      121 aatgacattc cctgtcaaaa atggtaaaat aagaaaaaat aatctgagaa tcgaggaaaa
      181 aagatgcaag aaaagatttt ggtaactggt ggtgccggtt ttattggaac ccacactgtt
      241 attgaattga tccaagcagg ccatcaagtt gttgtggtgg ataatcttgt caatagcaat
      301 cgtaagagtt tagaagttgt tgaaagaatt acaggagttg agattccttt ctatgaggca
      361 gatattcgtg acacagctac cctcagagat attttcaagc aggaagaacc gactggtgtc
      421 attcactttg ctggtttgaa ggctgttggc gaatcaacac gtatccctct tgcctactat
      481 gacaacaata tcgctggaac tgtcagcctt ttgaaagcca tggaagaaaa caactgtaaa
      541 aacatcatct tcagttcttc tgcgacagtt tacggggatc cgcacacagt gcccatcttg
      601 gaagatttcc cactttcagt gaccaaccca tacggtcgta ccaagctcat gctagaggaa
      661 attttgaccg atatttacaa agcagactca gaatggaatg ttgtcttgct tcgttacttt
      721 aacccaatcg gagcccatga gagtggtgat ttgggagaaa atccaaacgg tattccaaac
      781 aatctcttgc catatgtgac tcaagtagcc gttggaaaat tagagcaagt gcaagtgttt
      841 ggagacgatt acgatacgga agatggaaca ggtgttcgtg actatatcca cgttgtcgat
      901 ttggctaagg gtcacgttgc agctttgaaa aaaatccaaa aaggttcagg actaaacgtt
      961 tataaccttg gaactggtaa aggttactca gttcttgaaa ttatccaaaa catggaaaaa
     1021 gcggtgggac gtcctattcc ttaccgcatc gtagaacgtc gcccaggtga tatcgctgcc
     1081 tgctactcag acccagcaaa agctaaagca gaactcggtt gggaagcaga actcgacatc
     1141 acccaaatgt gtgaagacgc atggcgttgg caaagcaagc atccaaatgg atttgaagac
     1201 taagatgatg atttcaatca tcgtcccttg tttaaacgaa gaggaagtac ttcctctttt
     1261 ttatcaggct ctggaagctt tacttccaga tttggaaaca gaaatcgagt atgtctttgt
     1321 cgatgatgga tcaagtgatg ggaccttgga actcttaaag gcctatcggg agcaaaatcc
     1381 ggcagtccat tatatttctt tctctcgaaa ttttggcaaa gaagcagccc tttatgcagg
     1441 cttgcaatat gcgacaggag atttggtggt ggtgatggat gcagacctcc aagatcctcc
     1501 tagtatgttg tttgagatga aaaatgtact agacaaaaat gtagacttgg actgcgttgg
     1561 gacacggaga actagtcggg agggagaacc cttctttcgc agtttctgtg ctgttctctt
     1621 ttatcgcctc atgcaaaaaa tcagcccagt agctctgccg tcgggtgtcc gtgattttcg
     1681 tatgatgaga aggtctgtag tcgatgccat tttaagcttg accgagtcca atcgtttttc
     1741 aaaggggctc ttcgcctggg tgggtttcaa aacctactat ttggactatc caaatgtcga
     1801 aaggcaggct ggcaagacaa gttggagttt taggcaactc tttttctact ccattgaagg
     1861 gattattaat ttttcagatt ttcccttgat tatagccttt gtagctggtc tcctatcttg
     1921 ttttctttct ctgctgatga ccttttttgt tgtggttcgg accctcattt tgggcaatcc
     1981 gacatctggt tggacctctc tgatggctgt tattctcttt cttggaggca ttcaactctt
     2041 gaccattggg attctcggta agtatatcag taagatttat ttagagacta aaaaaagacc
     2101 actttatctt atcaaagaaa aaagtgacct tcctgatttt acagaaaaaa taaagtgaaa
     2161 agactataat tttacatgga aatgtgctaa actagaggga gtggattatc gccattgatt
     2221 taggcttcct ggtttccaat cagggcgcga gttgggcaat ttttaacagc ctctaagaca
     2281 tcctgactag gagaaatttc tttttccagt tggtcagggt catcgtaaaa acgcacgatt
     2341 ccattatcgt ggtaatcaaa taaatcagaa taagtttggc aaagtccaca ggcgatacat
     2401 cgttcaggta taagtgtgat tttcatgttc atatttatat tgtaataaga aaagtaaaaa
     2461 aaaacaagga gtaaggtatg gcaaaagaac cgtggcaaga agatatttat gatcaagaag
     2521 aatcaagagc agagcgtcgg catcgaaacc acggaggggc tgataggatg gctaatcgta
     2581 ttttgacgat cctagctagt attttctttg taattgtggt ggtgatggtc atcgttctca
     2641 tctatctatc atcggggggg agtaatcgca cagcagcctt aaaagacttt catgattctg
     2701 atgcaagtgt agtacaaatc tcatcttcaa gcagttctca gcctgagcag agttcagagc
     2761 cagaatctac ttctagtagt tcagaagaag ctgctaatcc tgaaggaacg attaaagttc
     2821 tcgcaggaga aggggaagca gctattgccg ctcgtgcagg aatctccatt gctcagttag
     2881 aggccttgaa tcctgggcac atggctacag gatcttggtt tgctaatcca ggtgatgtta
     2941 taaaaataaa ataggagccg atatgaaaac aattcaaatt gctattgatg gtcctgcttc
     3001 cagcggtaag agtacggtcg caaagattat tgctaaggat tttggattca cctaccttga
     3061 tacaggagct atgtatcgtg cagcgaccta tatggctctt aagaaccaat taggagttga
     3121 agaagtcgaa gcccttctag ccttgttgga ccagcatcca atcagctttg gacgttcaga
     3181 aactggagac cagcttgttt ttgtaggaga tgtggatatt acccatccta tccgtgaaaa
     3241 tgaagtgacc aatcatgttt ctgctattgc agcaattcct gaagtgcgtg agaaactggt
     3301 ttctctccaa caagaaattg cccagcaagg cgggattgtc atggatggtc gcgatattgg
     3361 aactgttgta ttgccacaag cagaattgaa aattttccta gtagcttctg ttgatgagag
     3421 agcagagcgt cgttacaagg aaaatattgc caagggaatt gaaacagacc ttgaaaccct
     3481 aaaaaaggaa attgctgcgc gtgactacaa ggatagtcat cgtgagactt ctcctctcaa
     3541 acaagcagag gatgctgtct accttgatac aactggtttg aacattcaag aagtagttga
     3601 aaaaatcaaa gcagaagctg aaaaaagaat gtaaatgtag aaaagccgat agattgatat
     3661 cggttttttt ctaaatttgt caaaatgctg attttagggt ataatagttg ctgttcgaga
     3721 aattttgatt ttcaaagaat agtgaatgat gataaggaga aaccatgaac aatttaccaa
     3781 attgtccaaa atgtaactca gagtatgtct acgaagacgg tgccctactg gtttgcccag
     3841 agtgtgctca tgagtggaat cctgctgaag ttgcagaagt agaagaaggt cttgtcgcta
     3901 tcgatgccaa cggaaataaa ttgactgatg gtgatacagt aactctcatc aaggacttga
     3961 aagtaaaagg tgcgccaaaa gatttgaaac aagggacgcg cgtgaaaaat atccgcatcg
     4021 tagaaggcga ccacaatatc gactgtaaga ttgatggttt tggtgccatg aaacttaaat
     4081 cagagtttgt gaggaagatt taagcatgtc aaaacactat aaacttgtat tttatagccg
     4141 tatcttcttg tttctagcgg cttttacggg agtttatctt gaaattacta ggcatggtgg
     4201 ttttgggatg cttctctatt acacggttct gtccaacctc ttggtaacta tttttaccct
     4261 ttatcttcta aaggttatga gccgtgtagg tgaaaattgg caaaggccaa gtctcttgcg
     4321 cttaaaaggt ggggtcacca tgagtatcat gattacctgt gtgatttacc atttcctctt
     4381 ggcgcccatt gcgactaatt tctataccct agaaaatttc ctttgccact atatcgttcc
     4441 catctggttt ttagcggata ccctcttttt tgacaaacag ggtcaataca agatttggga
     4501 tccagcagtg tggaccattt taccctttct gtatatgatg tttgctcttt ttaatggctt
     4561 ggttctaaaa ctcaatattc caaatgccaa ggataatcct ttcccttact tctttttgaa
     4621 tgtgaacaag ggttggaatg ttgtgtttaa gtggtgtctg attatctttg ttgcctatat
     4681 ggtagcagga tttattttct actttatcaa gcaaatcaag agaaagtcat cctaatactc
     4741 ttcgaaaatc tcttcaaacc acgttagttt ccatctgcaa cctcaaaaca ctgttttgaa
     4801 caacctgcgg ctagctttct agtttgctct ttgattttca ttgagtatga gatacaaggg
     4861 attcattttc gaatttaaga aggagtctac aaaccaatga ggcttcttct tttcttgctt
     4921 atttgataac tatcaaaaaa gtagaagatt aagagaaata tagaaagaga tttcatgaaa
     4981 caatttttag aacgggccag cattttggct ctctccctcg ttttgattac ctccttttcc
     5041 atttcgagtg ccctaccagc catgtttgac tattatcagg gttattctaa ggaacaaatt
     5101 gagctcttgg tgagcttgcc ttcctttgga atcatgatga tgttactgct aaatggtttc
     5161 ttagaaaaaa tatttcctga gcgcttacag attagtttgg gcttgctgat tttatcattg
     5221 agcggtacag ctcccttctg gtaccaagcc tatccctttg tctttggaac acggcttctc
     5281 tttggtttgg gtcttgggat gatcaatgcc aaggccattt ctattatcag tgaacgctac
     5341 caaggaaaaa ggcgaattca gatgttaggg ctacgcgctt ctgcagaggt cgttggagct
     5401 tctctcatta ccttggccgt cggtcagttg ttggcctttg gttggacagc tatctttcta
     5461 gcctatagtg ctggattttt ggtgctgccc ctttatctgc tctttgtccc ttatggaaaa
     5521 tcaaagaaag aagtcaagaa aagagcgaag gaagcaagtc gtttaactcg agaaatgaaa
     5581 ggcttgattt ttaccttagc tatcgaagcg gcagttgtag tttgtaccaa tacagctatt
     5641 accatccgta ttccaagttt gatggtggaa agaggattgg gggatgccca gttatctagt
     5701 tttgttctta gtatcatgca gttgatcggg attgtggctg gggtgagttt ttctttcttg
     5761 atttctatct ttaaagagaa actgctcctc tggtctggta ttacctttgg cttggggcaa
     5821 atcgtgattg ccttgtcttc atccttgtgg gtggtagtag caggaagtgt tctggctgga
     5881 tttgcctata gtgtagtctt gacgacggtc tttcaacttg tctctgaacg aattccagct
     5941 aaactcctca atcaagcaac ttcatttgct gtattaggct gtagtttcgg agcctttacg
     6001 accccatttg ttctaggtgc aattggctta ctaactcaca atgggatgtt ggtctttagt
     6061 atcttaggag gttggttgat tgtaatctct atctttgtca tgtacctact tcagaagaga
     6121 gcttaggatt gattcctaag tttttctttt gatactcaat gaaaatcaaa gagcatagtt
     6181 gattgagttt ggaatagtac gctgtagctg ctaaaatatt tctagaaatt aatttgactt
     6241 ttctaataga gttattcata tcttatttca atctactata gaaagctagc cgcaggttgc
     6301 tcaaaatagt gttttgaggt tgcagatgga aactgacgtg gtttgaagag attttcgaag
     6361 agtatgagat ttttataccc atacaatatt tgttttaggt ccttgtttac agactaattt
     6421 cttgataaaa tagaggttat gacgagatat aaagcaacta tttcctatga tggttatgcc
     6481 tttgctggct ttcagcgcca gtctcatgcg cgtagcgttc aggaagaaat tgaaaaaacc
     6541 ttgaccagat taaataaagg gcaaaccatt actgttcacg gtgctggtag gacagatagt
     6601 ggggttcata ccctgggaca ggtcattcat tttgacctgc cttatcagat ggatgaggag
     6661 aaactccgtt ttgccttgga tacccagtct cctgaagata ttgatgtgat ttcgattgag
     6721 cttgtggcag atgattttca ttgccgttat gccaaacata gcaagaccta tgagtttatt
     6781 gtggatagag gacgtcccaa aaatcctatg cgccgtcact atgccaccca ctttccctac
     6841 ccactcgatg tggaacgaat gcagattgca atcaaaaagc tagagggaac ccatgatttt
     6901 accggtttta cagcctctgg gactagtgta gaggataagg ttcgcaccat cacagaagct
     6961 agtttaatag tcgatgagac aggacaattt ttgaccttta ccttttcagg aaatggtttc
     7021 ttgtataaac agattcgcaa tatggtgggg actcttctca aaatcggtaa caaccgcatg
     7081 ccagtagagc agattgatct catcttggag aagaaggaca ggcaacttgc aggtcccact
     7141 gcagcaccaa atggtttgta tttaaaggag attcgttatg aagaataatc gtattttagc
     7201 actttctgga aatgatattt ttagtggtgg tggactgtca gctgatttgg ctacctatac
     7261 cttgaacggc ttgcatgggt ttgtagcagt gacttgtttg acagccttga cagaaaaagg
     7321 atttgaagtc tttccaactg atgataccat ttttcaacat gaattagata gcttgcgtga
     7381 tgtggaattt gggggaatta agattggtct tctccctact gtcagtgtgg ctgagaaggc
     7441 cttggacttt atcaaacaac gcccaggagt acctgtggtg ttggatcctg tcttggtctg
     7501 caaggaaacg catgatgtag ctgtcagtga gctctgccaa gagttgattc gctttttccc
     7561 ttatgtcagt gtgattacgc ctaatctccc agaagcagaa ttattatccg gtcaggaaat
     7621 taaaaccttg gaagacatga aaactgcagc gcagaaattg catgatttag gagcgccagc
     7681 agtcattatc aagggaggca atcgtcttag tcaggacaag gctgtggatg tcttttatga
     7741 tggacagacc tttactatcc tagaaaatcc agttatccaa ggccaaaatg ctggtgcagg
     7801 ttgtaccttt gcctctagca ttgccagtca cttgattaaa ggtgataaac ttttgccagc
     7861 agtagaaagc tctaaggctt tcgtttatcg tgctattgca caagcagatc agtatggagt
     7921 aagacaatat gaagcaaaca aaaacaacta aaatcgccct tgtatcccta ttaaccgccc
     7981 tttctgtggt tctaggttat ttcttaaaaa tcccaacacc tacaggaatt ctaactcttt
     8041 tagatgctgg tgtcttcttt gcggcctttt actttggtag tcgtgaagga gcggtagtcg
     8101 gaggactagc aagtttcttg attgacctct tatcaggcta ccctcagtgg atgttcttta
     8161 gcttggtcaa ccatggcttg cagggatttt tcgcaggatt taaaggaaaa agtcagtggt
     8221 taggccttat tttagcaact attgccatgg taggaggcta cgccttgggt tctactttga
     8281 tgaatggctg ggcagcagcc ctcccagaaa ttctaccaaa tttcatgcaa aatatggtag
     8341 ggatgattgt aggatttatt cttagtcaaa gtatcaagaa gattaagtaa tactcttcga
     8401 aaatctcttc aaaccacgtc agcttccatc tgcaacctca aaacactgtt ttgagcagcc
     8461 tgaggctagc tttctagttt gcactttgat tttcattgag tataaagagg ttgagtaaaa
     8521 agtatttcaa ataagaaaaa cgcatagtat caggtgttga atgaactgcc ccccaaaagt
     8581 tagacagaaa aaatctaact tttggggtgt ttttattatg aaa
//
LOCUS       DAVHBD010000062         8579 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000062 DAVHBD010000000
VERSION     DAVHBD010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8579
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.062"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            89..2698
                     /locus_tag="VVK04_001916"
     CDS             89..2698
                     /locus_tag="VVK04_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU3990533.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAASGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            2731..4671
                     /locus_tag="VVK04_001917"
     CDS             2731..4671
                     /locus_tag="VVK04_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEU3990534.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRFKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAASHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            4668..6275
                     /locus_tag="VVK04_001918"
     CDS             4668..6275
                     /locus_tag="VVK04_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990535.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFVDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            6290..7030
                     /locus_tag="VVK04_001919"
     CDS             6290..7030
                     /locus_tag="VVK04_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990536.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            7033..8352
                     /locus_tag="VVK04_001920"
     CDS             7033..8352
                     /locus_tag="VVK04_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU3990537.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYCKSY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            8485..>8579
                     /locus_tag="VVK04_001921"
     CDS             8485..>8579
                     /locus_tag="VVK04_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU3990538.1"
                     /translation="MAAEVLNLQLVSVQVDETDEVDGMRFSTFST"
BASE COUNT         2976 a         1059 c         1599 g         2945 t
ORIGIN      
        1 gaatccaaag gattctccct ttttatttaa ataagtctgt ctagctatag atatattaag
       61 tttgataaaa tttcttggag attttgttat ggattataat ttcaatttgg agcatccttt
      121 ctttttcact aataatgatt atagtacaga tactagcata aagtaccaag taagtctgcc
      181 ttttaattgg cacgaagtaa tgaataatga tgagtgggtt tatcaatacc ctattggaaa
      241 atttgttgaa agacaagggt ggaaaataca cattagttca gagtataaca gttcacatga
      301 attgttacaa gatgtagcaa aaatttgcca tgaaatgcga attccattta aacatcttag
      361 tacagaagac aaatttatca tgcgaaacgg gaaattggtt agtcgaggat tttctggtaa
      421 atttattaca tgttatccaa atcaaaatga attagagtcg gttttgcaaa ggttagaaag
      481 tgccttaaag caatataatg ggccatatat tttaagcgat aaacgttggg atgaagcacc
      541 aatatatctg aggtatggtg tgtttaggcc gtcaagggat gatgaaaaga aggttgctat
      601 tgatgaatta attgttggcg atgaagttgt taaagatgaa cgtttaccag tatttaaaat
      661 tccaaaaggt atagtgcccc ctgacttttt gaataaatgg cttgacaaga aagataaaaa
      721 acagggagac tttcccttta ttatagataa tgcaattaga ttttcaaaca gtggtgggat
      781 atataatgct aggctaaaag aagatgggaa aaaaataatt ttaaaagagg ctagaccgta
      841 tacaggtcta ggatttgatg gtacttattc ttcagagaaa ttagcttcgg agtgcaaagc
      901 actaaaaatt ctaaatgaat ggagtgagac gcctaaaata tactggcacg gtaagatctg
      961 ggagcacacc ttcttaggaa ttgaacatat gaagggcgtt ccactaaata gatgggttac
     1021 caataatttt cctttatatg aagttgttga taagaccaaa gattatctat tgagagtttc
     1081 aaagatagta gaaaaactca tcgatttaac gaataagttt cattctgaaa atgtatatca
     1141 tcaagattta catttaggaa atatcttggt taaggatgaa gatgagatta gtataataga
     1201 ctgggaacag gctgtctttt caaatgatga aaaagttgta cataaagttg cagcctctgg
     1261 ttttagagca tggcgagaaa cacttcccag tgagatagat tggtatggta ttagacaaat
     1321 agctcattat ttatacatgc cactagtaac tacatcggat ttgacataca actatgtaag
     1381 tcaaaccagg atagaaggaa aaaaactatt tgagtctttg ggttatacaa gagaacatat
     1441 agattatgta gaaagtttat tgtcatatct agattctaaa tgtccacaga ttgagaatat
     1501 ttccaggaaa aaagttttaa aacccatgca tgagattaga actatcgaga gtgagcaaga
     1561 tatacaagat tttattataa aattattgag agggtttacg ctaacttatg gacagtggcg
     1621 taaagaattt caatcaagat tcttcccagt tcattattat ggtctgaatt ttaatcaagg
     1681 aattgcgttt tcagatttag ctatcctttg gagttatcaa caactagcta agaaagtaaa
     1741 aaatttcaag tttgatgact attatgagat tcgaacacag gttattaatg aggcagtaaa
     1801 taattttaag aaatcgtccc tttctggtct ttttgatggt aaaattggta caatctggct
     1861 catttatgaa tttggggaga tagatcgggc agttgaactt tttacaactc attttataga
     1921 gatatttgag aattcacaaa ataaaaattt atatagtggg caggctggaa ttttactggt
     1981 tggactgtat tttcttagta aaggggaaat tgataataaa ctaggagaag aaatactaat
     2041 taggcttaga gaatatactt taaattatat agaaaatcca gaaacttttt gtaaagttgg
     2101 cgctagtgat gttcagagta atgatcctta tgagaatttt ggtggattac tatatggtca
     2161 cgcaggggta gcttggctct tcggtgaagc ttataaatta actggtgaaa gtatctataa
     2221 aaatggtcta gaattggctg tagataaaga attagttgct tataaagtag atagtaataa
     2281 ttcattgcag tacagccaag gtcatagatt actaccatat ctagcaactg gaagtgctgg
     2341 cctgctttta cttattaata gaaataaaga aatcttgtca agcaaatact taaaatattt
     2401 aacttcttta gagagggcaa ctgatgtagt tttttgtgta ttaccaggtt tatttaacgg
     2461 attttgtggt cttgaagttg ctaataatat atatagtgat atcgatgata acttttcagg
     2521 acaaaagaaa ttaattgaac aactttatag atatttgtgt gtaattgaag aaggatttgt
     2581 tattgcggga gataatggtt taaagataac aacagatatt gcttcgggat ttgcgggtgt
     2641 tgcaattgga ttggtatcaa taatggataa taaattgacg attcttcctc aaatataata
     2701 tttagatacc attattaagg ggtcatactt gtgaatcaga gtaatgaaat atttttaaat
     2761 acaatacagg aaaaaacaca ctataagagg tctatctctt catcatttca ggaattaaaa
     2821 aaatggaatt ctttgatatt taggagaggg cgatattggt accaatttga taattggagt
     2881 atacccaata ctggtgtaat aaaggaatgg tatgtcgaag ataatgactg gattcctaag
     2941 gttagttctt ccagtttaga caattcaaat tcacttaaaa ttgtctttga tgtggaaaaa
     3001 tatactttgc cagatgatag tatcttacag gatgttagga tttcatctga tgagagttat
     3061 atagttttgg ttgtatcctc actgcgtagc actaatttaa ttggaataaa aaaatatact
     3121 atggaagagt tatttatcat tgaagatatt tcagtagaaa gttcgttcta tttgggtaaa
     3181 ttcggtgtta tgtatactcg cttcaaagag tacgggaggc caagtaagtt attctataaa
     3241 tcttttgata gctttacaga agaggaactg tttgaagaaa acgaatgctc ttttcgatta
     3301 aaaatagtcc acattgatag caataattgt tttgtaaagt cagtagactt tcagaaaggc
     3361 aggatttttc tatacagttt cgaccggacg ggttttgtta gacactctta cacagaaacg
     3421 gtagccccaa cacctagaga tatcgctcta tttagtacag aaaaagcaca gtactttctt
     3481 gggctctctt caactgaaga aaagaaagat caactaattc taagggaaac ttcttcggga
     3541 gacagagttt ctattactat accatatcaa gatagggcta gaagagttca ctgtatagga
     3601 cgttatatcc ttttagactg ttcaaacgca gcgaattccg tcttttatct tgctacattt
     3661 aaaaataata gtttgaggga gttgagtgtt aataagataa catttgatga aaagacaaca
     3721 ctttatgaaa attcattttc tgatcgtgtt cttctgtttt tagagaggag aactttttac
     3781 gaaaaaatac ttagttttga tttaatagaa aatacattaa aaactgaatt tgaaagaccc
     3841 atcataaaat cgaataatac taaatatttt tctaaggtga tttggactaa aaaagacagt
     3901 tatgatgtaa gcataccgat ttctttattt tggaaaagtg aagatacgga tgagctccca
     3961 agaagaaaaa aatgtattct aagtgtctat ggggcttatg gtaagaatga taattctgat
     4021 ttagatgaaa ttatgttatc tataatagat gcaggtttta tttatgctat agttcatgta
     4081 agaggtggag gctatttggg tggtgaatgg tatcgctcag gaaaggcgtt aaacaaatgg
     4141 aattctatca gagattttat tgagggagta aattatttaa gggaaaatga tgtaattgac
     4201 agtaagcgat taggtttaat aacttctagt gcaggtggaa taattgctgg tgcggtgttg
     4261 aacgaggaaa aaaatttatt gcaaagcatt ctcttatttt cgccatttat aaatccttat
     4321 gatacacttc agaatccaaa tgatcctctt tctaagaccg aaatagcaga gtggggagat
     4381 attagagacc ctgaagtaaa ggcttatata aagtcatatt cgcctatgca aaatattgaa
     4441 aaggcacgag actcaaatac tgttatagtt aatattttgg gtgagaaaga cccatatatt
     4501 aataataacg aagtgataga gtggtcaaag aaattaaatt ctattggagt taaaagtttg
     4561 ttgtatttaa acaaagcagc tagtcatgga ggttttactc catcagatgt tctcttaatg
     4621 attgatactt taaattattt ctttgaagaa gtgggaagga ataacttatg aattatttaa
     4681 aatttataaa aaagactaaa cttatattaa tggggatttt aatatttcta tcttcgttta
     4741 atggtgtctt gctctcagga attattgtat atgcaggtag tttaaatcag acttcctcat
     4801 tttctgacgt tctaagattt ggtgctataa gtattctggg ttggtcagca atctatatat
     4861 caaattacta tttagaagta acggaagcat caataacgaa agatataaat gtaaaaatta
     4921 aacaaggata ttttagagaa cagtatcttt cttctgaaat ggttaaagat tactcatcta
     4981 ttatttcagt tttgtcaaat gatttgagat taatcgaaga aaactatttt agacaaattt
     5041 ttgaaataat ttcttcaata ttgttgttca tcgtctctct aagttttatg ctttatttaa
     5101 acttcctagt ttcaataata tttattgtat tatcagcatt gccgattata gtacctgtct
     5161 ttatgaagaa gatgttgtct aattcagcta atgagtactc taacagcaat gcagagtata
     5221 ctcacataat aaaagaaatt tttaatggtt ttaagacatt aaaatcttat tctgttacta
     5281 aagaaataat tagtttgtcg gataaaaagt tggataaact agaagattct acttttaatt
     5341 tgaaacgatc agaggttctt tcaaaattgg ttgcagtact aatttcaggt ttttgctttc
     5401 tagttccctt ggttgtagga tgttattttg taatttatca taaaagcctt tcttttagtg
     5461 aactgatagg tattttctta gcaaacgata aagttttagg gccgatacaa tcaattgcct
     5521 attcattaaa taagataaat acaaccaaag atttaaggaa accgttttta aaatacttaa
     5581 gtggagagaa gaattttgta gacgctgaac atgataataa cggactgtat acttcatcaa
     5641 tagatgagat acacatgaaa gatgttgtat attctattac accagaaaat aaattaagta
     5701 ttgacttctc atttaagtca ccatttaggg tattattaac aggaacttct ggcagtggga
     5761 aaacaacgat tttaaattta attaatggtt ctttaaagcc acaaaaaggt tatgtaaatt
     5821 tgttatcaca tgggaaaaag agttcagatt caataccaac agttgatcag acaccatata
     5881 tttttgacac tactattcgt gagaacgtaa ctttatttca aaatgaatat ttttcagatg
     5941 atcagataat tgaggtgtta aaaaaggtaa atctatatga agaattagaa aagatagata
     6001 tactaaatta tcaatgtggt gaaaatggta gtaatttgtc tggaggtcaa aaacaaaaaa
     6061 tagctttagc tagagctctg attagaaata ataaagtgta cttatttgac gaaatatcag
     6121 ctaatttaga taatgataat tcaaattcca tacatgatat tctgttcaat ttaggtattt
     6181 catttattga agtttcacat cattatgact taaatgacaa gagatacact gatatatata
     6241 aattggaaaa tggaacactt ttcaaaatta agtgattgga ggcaagaata tggataaaga
     6301 ttatatatta aaagtgaaag ggctgtatca tcaattttta ctaggaaata ataaaacgtt
     6361 gcaagtgctg aaaaatgttt ctctttctgc ttcgagagga gaatttataa gtattctagg
     6421 aattagtggt tctggaaagt caactttatt aaaatgtatt tctagtttgc ttgaaccaac
     6481 aagtggggaa gtaattttaa atggaatcaa cccctataaa atcagaaatg caaaattgtc
     6541 aagtataaga cgtaacgaag tatcttttat atttcaagca tacaatttaa taccttccct
     6601 gccggtaata gaaaatatag cacttccttt gcgattatca caaaaaaaat taactattaa
     6661 aaatgtagaa aacttactca aaagaatgaa gtttaatgct ggcttaaacg attttgttgg
     6721 aactctgtct ggtggagaac aacagaaggt tgctatagct agagcggtta ttgctgatag
     6781 tgatataata tttgctgatg agccaactgg ggctttagac agcgtttctc gtgaagtaat
     6841 ttttgaatta ttgagagagt tagtaggggc gggtaagtgt gtaattatgg taacgcacga
     6901 tatagaattg gcctcgaaaa ctgatcgtgc attaatattg aaagatggaa aaattttcaa
     6961 agaacttcat agacctagcg gggaagagtt gtataaaatc ttagaggtac aatcaactac
     7021 ggaggaatag agatgctcag attagtttac tatcaatttt tacataataa gaaacaatgg
     7081 ttaggcgttt caccagtaat ttttgtttcg agtttagtta tgggattggc tgttaatggg
     7141 gtaattaatg ttgagaataa ttcgcaagta tttgtcggac ttccagatcc taaaccaatt
     7201 tttatgtttc cgatagtatt cggaggagta acattattct ttgtgctctc taacataata
     7261 aatatgttgg ttgaaatttt tagagatgat tacgaacttt tggaggtgtt gggagcaagt
     7321 cgccttcaac tatcatttct tgtgggggga cagattttta tcatttcctc gattattagt
     7381 tttattgcat atctatgctc tatatttgtt acgtcaaatt attattattt tttacaatac
     7441 tttttcgggg aaaatatatt acctgatatc caatttcaaa cgagtgctgt tggatgtatc
     7501 attacagtag tgttgatttc atttttagcc tttctaagtg gttgctttta tacgttcaag
     7561 aagattagaa ataggaagag ttctaaaata aggcatgttc tttcaatagt aaaaagaata
     7621 ctgctattgg ctggttttag tgttatctgg ttgctttctt tgcaacaaat tttccaagat
     7681 agcacaattt tagcgaaggc ccagataata ttcaatattg taatcttaga tattgtgatt
     7741 atttatcaat tatctccttt tatacagtca tgttttatca aactactttc tataattata
     7801 tttagaaata attttatgtt cattgtttcg aagtggaatt tactatattg taagtcttat
     7861 ataaaatcta tcagtgctgc aattacagga gctatattac taatttctag ttttcaaatg
     7921 atttctcaga atatactatc tcaatttcaa gatgacagtg atttagagct aaaagtagca
     7981 tttattgtct atgtaggagc accaattttg atagtacttg caaatattat ttcaattgca
     8041 tttttgtcat cgcatcaaga aaggattgag attcagcaat ttgaaatttt aggaacttct
     8101 aattaccaga tggttaagat taaagttggt gaggctatat ttttgacatt tgttacttca
     8161 ttaattgcat ttttacttaa cattaaaatt atggctttaa tatactactc tttagaggat
     8221 attttaatag atgatatgaa tcttttgggg ttaatacttc caaattttat agtatctatt
     8281 attttattta ttttaatatt tattactaaa agttcctatt ttatctttaa gaatgcaaaa
     8341 attatttctt aaaaatttgt aagttttcgc tatataaaat agttaaatct attttgtatc
     8401 attgcttgca ttttactggt ggagagagta tatgagggtg gataaagtac ttaatcccaa
     8461 aaatttaaat aggaggagct agctatggca gcagaagtat taaatcttca attagtatct
     8521 gttcaagttg acgaaacaga tgaagttgat ggaatgcgat ttagtacatt cagtacaaa
//
LOCUS       DAVHBD010000063         7437 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000063 DAVHBD010000000
VERSION     DAVHBD010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.063"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..116
                     /locus_tag="VVK04_001922"
     CDS             <1..116
                     /locus_tag="VVK04_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU3990539.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="VVK04_001923"
     CDS             135..1652
                     /locus_tag="VVK04_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU3990540.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="VVK04_001924"
     CDS             1777..3105
                     /locus_tag="VVK04_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU3990541.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3357..4223
                     /locus_tag="VVK04_001925"
     CDS             3357..4223
                     /locus_tag="VVK04_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU3990542.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4239..5078
                     /locus_tag="VVK04_001926"
     CDS             4239..5078
                     /locus_tag="VVK04_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU3990543.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="VVK04_001927"
     CDS             5351..5803
                     /locus_tag="VVK04_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU3990544.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKEEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="VVK04_001928"
     CDS             5900..6244
                     /locus_tag="VVK04_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990545.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            6531..7175
                     /locus_tag="VVK04_001929"
     CDS             6531..7175
                     /locus_tag="VVK04_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU3990546.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7344..>7437
                     /locus_tag="VVK04_001930"
     CDS             7344..>7437
                     /locus_tag="VVK04_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEU3990547.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRA"
BASE COUNT         2283 a         1315 c         1515 g         2324 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgaaac tattgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccat
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaatagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa cccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaatgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgaat atcttgtaaa cgggtttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aggagtgggg acctaaagac gtagttcgta cgggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac actttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cagatgcttt gaaagccttc
     3061 actgaaaaag cgaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 taaaaagtag ttttttaaag aacctaagag tgtatacccc cttttccctc tacacagata
     3181 gtgtaagaaa agggggcttt tgtttaaaat gtaagaaact gtcacgaaat taaaatgaag
     3241 ttcttacata agcgaatcat aaaaaatttc attttgattt taaaacagtt caagaaagtc
     3301 aaaaaattat tctatttgaa agagaggtgc cgactgtgaa agtcaataaa atccgtatgc
     3361 gggaaacagt gatttcctac gctttcctag caccagtatt attcttcttt gtcatctttg
     3421 tgttggctcc gatggtgatg ggcttcatta caagtttctt taactactca atgactaaat
     3481 ttgagtttgt aggcttggat aactatatcc gtatgtttaa agatcctgtc tttacaaaat
     3541 ctctgattaa cacagttatt ttggttattg gatctgtacc agttgttgtt ctattctcac
     3601 tctttgtagc atctcagacc tatcatcaaa atgtcattgc cagatccttc taccgtttcg
     3661 tcttcttcct tcctgttgta acgggtagtg ttgccgtgac agttgtttgg aaatggattt
     3721 atgacccact atcagggatt ctaaactttg tccttaagtc cagccacatc atcagccaaa
     3781 acatttcttg gttgggagat aaaaactggg cattgatggc gattatgatt attctcttga
     3841 ccacttcagt tggtcagccc atcatccttt atatcgctgc catggggaat attgacaatt
     3901 cactggttga agcggcgcgt gttgatggtg caactgagtt tcaagttttc tggaagatta
     3961 aatggccaag ccttcttcca acaactcttt atattgcaat catcacaaca attaactcat
     4021 tccagtgttt cgccttgatt cagcttttga catctggtgg tccaaactac tcaacaagta
     4081 ccttgatgta ctacctttac gaaaaagcct tccaattgac agaatacggc tatgccaaca
     4141 caattggtgt cttcttggca gtcatgattg ctatcgtaag ctttgttcaa tttaaagtac
     4201 ttggaaacga cgtagaatac taaagaaagg agacagctat gcaatctaca gaaaaaaaac
     4261 cattaacagc ctttactgtt atttcaacaa tcattttgct cttgttgact gtgctgttca
     4321 tctttccatt ctactggatt ttgacagggg cattcaaatc acaacctgat acaattgtta
     4381 ttcctcctca gtggttccct aaaatgccaa ccatggaaaa cttccaacaa ctcatggtgc
     4441 agaaccctgc cttgcaatgg atgtggaact cagtatttat ctcattggta accatgttct
     4501 tagtttgtgc aacctcatct ctagcaggtt atgtattggc taaaaaacgt ttctatggtc
     4561 aacgcattct atttgctatc tttatcgctg ctatggcact tccaaaacaa gttgtccttg
     4621 taccattggt acgtatcgtc aacttcatgg gaatccacga tactctctgg gcagttatct
     4681 tgcctttgat tggatggcca ttcggtgtct tcctcatgaa acaatttagt gaaaatattc
     4741 ctacagagtt gcttgaatca gctaaaatcg acggttgtgg tgagattcgt accttctgga
     4801 gtgtagcctt cccgattgtg aaaccagggt ttgcagccct tgcaatcttt accttcatca
     4861 atacttggaa tgactacttc atgcaattgg taatgttgac ttcacgtaac aatttgacca
     4921 tctcacttgg ggttgcgacc atgcaggctg aaatggcaac caactatggt ttgattatgg
     4981 caggagctgc ccttgctgct gttccaatcg tcacagtctt cctagtcttc caaaaatcct
     5041 tcacacaggg tattactatg ggagcggtca aaggataata ctctgcgaaa atcgaatgca
     5101 aactacgtca gcttcacctt gccatactta agtattgcct gtggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagaa gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actatctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctgataga
     5581 agggcatgaa tattcgagct acggttcacg tatcaaagaa gaggcagtag cattcgacga
     5641 agcgagtgac attggctttg ttcattgtta tgaacactac ccactcttat tgggttatca
     5701 caattttgcg attttcttcc caggtgagcc acatcagcca aatggttatg caggcatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat cttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagtatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aggggcattg tgaatggatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatggcgcg
     6061 ctcgatctta agtagggcag ctgcaactgc ggcagcaaga gtaggattat tgactaagat
     6121 ttttggatgg attttacgaa tagctgtgct cgcagctgat gtatatggta attttgccaa
     6181 caatattgct gtagcttggg atgcacatga taaaatccct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
     6301 gcttgcaatg ataattcgtg gagggctaga tggatttaat gagcatactt ggagtactat
     6361 tttaattgct tcgctgtccg ggatatatat agattatatg tccatagata aaagtagaaa
     6421 aaagtccaaa agaaaaaaga aaaaatagat ttgttcatgg tagggactta tgaaagtttt
     6481 actgacaaaa aagaaaacag tttacaaaga aaaatgatgg aggagcaaac atggcacaaa
     6541 aaggagtaag ccttatcaag gcagcatttg atacagataa ctttctcatg cgttttagtg
     6601 agaaagtctt ggacatcgtg acagccaatc ttctttttgt cgtctcttgt ttgcccatcg
     6661 tgacgattgg agtggctaaa atcagcctct acgagaccat gttcgaagtt aagaagagca
     6721 gacgggtgcc tgtttttaaa atctatctaa gatctttcaa gcaaaatctg aaactaggtc
     6781 ttcagctggg tttaatggag ttaggaattg tgtttcttac cctttcagat ctctatcttt
     6841 tctggggtca aacagctctg cccttccaat tgctgaaagc catttgttta ggtattctga
     6901 tttttcttac tatcgtgatg ctggctagtt accctatcgc ggcacgttat gacctatctt
     6961 ggaaagaaat tcttcaaaaa ggattgatgt tggctagttt taactttcct tggttcttcc
     7021 tcatgttagc cattcttgtc ctcattgtga tggttcttta tctgtccgcc ttcagtctac
     7081 tcttaggtgg ctcagtcttc ctactttttg ggtttggact attggtcttt atccagactg
     7141 gattgatgga gaaaattttc gcaaaatacc aataggagcc ttatttctga aactactttc
     7201 aaaggctcca aacgctattc tataagcgag aaactaaaat ctaagtgtct ataagatatt
     7261 gaaagccttt tcggtaaagt gtatactaaa gaagtaaaga aaaatctgct ttagcagaaa
     7321 ataaaaataa taggagaaaa tctatgtcag atttgaaaaa atacgaaggt gtcattccag
     7381 ccttctacgc atgttatgat gagcaaggag aagtaagtcc agagcgtacg cgtgcct
//
LOCUS       DAVHBD010000064         7246 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000064 DAVHBD010000000
VERSION     DAVHBD010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.064"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(201..1592)
                     /gene="argH"
                     /locus_tag="VVK04_001931"
     CDS             complement(201..1592)
                     /gene="argH"
                     /locus_tag="VVK04_001931"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU3990548.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGVLSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAYHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TTGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(1621..2818)
                     /locus_tag="VVK04_001932"
                     /pseudo
     CDS             complement(1621..2818)
                     /locus_tag="VVK04_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(2835..3641)
                     /locus_tag="VVK04_001933"
     CDS             complement(2835..3641)
                     /locus_tag="VVK04_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU3990549.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3848..4489)
                     /locus_tag="VVK04_001934"
     CDS             complement(3848..4489)
                     /locus_tag="VVK04_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990550.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4486..6594)
                     /locus_tag="VVK04_001935"
     CDS             complement(4486..6594)
                     /locus_tag="VVK04_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU3990551.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQSRAILAGFVKTNFYLLLGGSLVIDLGLFLVLDYRPKLLFPSL
                     LLSQFLLLQLYLFISWLTYLMIQKMTVSSMLKGFSSVKLGLIFNYVMKIGTTILLTAL
                     LIGVGKSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIRQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6646..6933)
                     /locus_tag="VVK04_001936"
     CDS             complement(6646..6933)
                     /locus_tag="VVK04_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU3990552.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
BASE COUNT         2181 a         1659 c         1192 g         2214 t
ORIGIN      
        1 ctgccaagcc acatagtgtg tttactacta tgtgtccatg tcaccatgaa tcgccgaacg
       61 atttaacgag aaagtatgac ttttacgttt atcccaactc aattatgaca tttttttcaa
      121 aagtcaatat atctcacttt ttcaacgaca agaaagaggc tgccaatcga ccaacctctt
      181 attctgaacc catcactcca tcacttttta gcttcattcg ctttcttagc gactgcaatc
      241 tggtattcga cttggtcaaa ccctgtgcct cccaaggaat ttcgtctttg aacagcagtt
      301 ttaggttgca agtagacata gatatcctcg gtaatgagag aatgataggt ttgtaattcc
      361 tccaaagtcc aatcttgaag atttttagca gacttgatag agtctagcac taatcttccc
      421 acaacctcat gagcttctct aaatggcaag cctttccctg ccaaataatc tgccaactca
      481 gttgcatttg aaaagtcctt ctctgttgat tcttgcattt tttccttgtt tacctgcaaa
      541 ctagataaca tacctgccaa cacatcgagg gaatttaaaa tcgtttcgac cgtatcaaac
      601 attccttcct tatcttcttg caaatcctta ttataagcta aaggcaagga cttcatgact
      661 gtcaacagtc caaacaaatg cccataaact ctgccagtct ttcctcgaat caactcagcc
      721 atatctggat ttttcttttg gggcataata gaggaacctg ttgtaaacgt atctgacaag
      781 gtaatgaatt ggtactcaaa actacaccaa ttgatcattt cttcgcaaaa acgactcata
      841 tgcatcatga gtatgctggc atttgataga aattctaaga taaaatcgcg gtcactaaca
      901 gcatccaaag aatttgtata aggttgctta aactccagca aatcgctaga caattggcga
      961 tcaatgggga aagtcgttcc tgccaaagct gccgcaccta aagggcatag gtctgtatgc
     1021 ttctggttaa attcaaaacg ttcactgtct ctttgaaaca tattgtagta agccatcagg
     1081 tggtaggcaa aactaatagg ctgggcatgt tgcagatggg tatagcccgg catgatcgtc
     1141 gccacatgat tttccgccaa gtctaataaa acacccttaa gatgagccag tttatctagg
     1201 acatagccta gttgttcctt gagatacaag tgcatatctg tcgcaacttg gtcatttcga
     1261 gaacgagccg tatgtaactt ccctgcaagg ggaccaattt tttctgtcag caacacttcc
     1321 atattcatat gaatatcttc gtttgcgata tcaaagtcaa gttgacctgc ctctagctct
     1381 tctaaaagct ctttcaagcc tacttgaatc ttttctgact cctccaaact caaaacgccc
     1441 gtctgaccca acatctgaac gtgggctaaa gaaccaatca catcaaattt agctaatttc
     1501 tggtcaaaag atatactcgc accaaagcgc tctacccagt cttcgacagt accttcaaag
     1561 cgaccacccc ataattttgt attcttagcc atatcacatc cacctctcta tccaatcgtc
     1621 ctatttggcg cttttttgaa cctcagaatg aaccttggtt ggaagtcccc ataactcaat
     1681 aaagccaaca gccgcatctt ggtcaaaggt atctgcacta gtatacgtcg ccaaattttc
     1741 atcgtaaaga gaatttggtg atttccgagc cacgacctga gcgctccccc ttatacagtt
     1801 tgacttttgc agtcccattg acaacttttt gagtctcttt aatataagca atcaaggctt
     1861 gtgtagccga actaaaccac aaagcattat aaatgagatt tgataattca ttttctatga
     1921 ttggtttaaa atgagccact tctctcacaa gcgtcaagtc ctcaatttcc ttatgagctg
     1981 tcagcagggt cactgcacct ggacactcat agatttctct tgatttaatc ccaaccaagc
     2041 gattttccac gtggtcaatc cgtccaaccc catgttttcc agctatttca ttgagttttt
     2101 gaatcaaatc tgccaatttt aacacttctc cattgaggga aactggaaca ccttcactaa
     2161 actcaatctc aatgtattct ggcatatctg gagcttgctc tggagaagtt gtgatgccaa
     2221 aggcttcttc tggagcctga ttccatggat tttccaaaat accacactca ttggcacgtc
     2281 cccaaagatt ttggtcgaca gagtagggat tgtcaaggtc agcaggaaca ggcaccccat
     2341 tttccttggc ataataaatt tcttcctccc gagaccattt ccattcacga actggagcaa
     2401 tcacttttaa attgagatcc aaggctgcaa tcgatacttc aaaacgtact tggtcattcc
     2461 ccttaccggt acaaccatga gcaattgtag tcgctcctgt ctgatgcgct atttcaacta
     2521 attttttaga aataagaggg cggctcaagg cagataccaa ggggtacttt tgttcataat
     2581 aggcatgtga ctgaagagcc actagcacat aatctgtagc aaattcgtcc ttgacatcaa
     2641 tgacataaga ttcgactgcc ccaaccttaa gagccttatc atggatgaaa tctaagtctt
     2701 tcccttcacc cacatccata caaactgcaa caacatcata gtctttcttc agccaggtaa
     2761 tagcaactga tgtgtctaaa ccgccagaat aggccaaaat tactttttct ttactcatgt
     2821 tcttttcctt ctttctattt ttcaatggac gctttaaagg catcctcaat gagtttgtct
     2881 aattccccag actccttcaa cttttgaatg gttttatcga ctgcctcttt caattccttg
     2941 ctatcttttt tcatggctac cgcgtaggaa tcatcttgct ctttttcaaa attgaggtct
     3001 gcgattgcta aatcaggatt attttccaca aatcccttgg aaacaggttc ttcaaagata
     3061 acggcatcca cttgtcctga ttttaaatct gtgattaaat tcccattttt aggcagagat
     3121 acgagggaag aattttgtag caaatctttc gccatcgtct cttgaatcga acctttctgc
     3181 gctccgacct ttttctgcgc caaatcgttg acagactgat aagtggctaa atcagatttt
     3241 ttgacaatga gtttattttt tgcagtatag tagggagttg aaaaatcaaa caccttgctc
     3301 cgttcatctg tcttagaaac acctgatatg gcaaggtcag cttttcctga ttgaacgcta
     3361 gccagtacat tgtcaaaact cataggagat agttccaatt cgacacctag ttctgttgcg
     3421 atagccttgg ctaattcgat atctgaaccc acaatctgat ttttcccatc aaccactttt
     3481 tgatattcaa atggagcaaa atctggattg agggctacaa ccaattttcc tttggacttg
     3541 atggcttcaa ttccagccga ttgattgtta ctacaagcaa atagtagggg gagcatcact
     3601 aaaccaaaca tcgtcatcaa caccttcttc atcttattca taacaaagcc tcctttatgt
     3661 ttattctttt ttattgtata aataatactc ctatactcat cctttgtcaa gcctaaattg
     3721 aaaaaatttt caatttgaaa caaaaaaaac ctagaaatac tacataaaat gtcattccta
     3781 ggcgtattta tgctattttt ctctggaaaa catgagtatt cagccagtca aaaggagctg
     3841 aatgaactca ttttccctcg cccaattcaa tgacacgatg acattgttgg gctacataag
     3901 catcgtgggt cacaataatg actgttttcc cttctcgatt catctctaag agaaacttca
     3961 agaccaaatc tctattttca ggatccagcg aacctgtagg ttcatcggct aaaatcagct
     4021 ggctgggttt taagatggct ctagcaactg caattcgttg ttgttcgccc ccagacaact
     4081 cggagaccct ttgatgcaaa gtagctgaca aacctactct ctctaaaatc tcttccacct
     4141 ttttgagctt gtctttctta ggcaatttca catatttcag cgccagcatg agattgtact
     4201 cgaccgtttc atcatcaatc agggcaaaat tttgaaacag ataagagata tgttcacgga
     4261 ttattgtttg cgacttagca gaattaaccg ctagatttgt ctgaccaaaa atctcatacc
     4321 gtccgctata atcaccatct atcaaaccca ataaatttaa caaggtcgac ttcccactac
     4381 cactcttacc aacaatagct accaaatccc cctgatcaat cctgagagat aagttatcca
     4441 aaatcacttt tcccccaatg gttttggtaa tatttttcaa ctcaatcata agatgccccc
     4501 tttcaataac tctactagac ttcttttctc catcctagaa gctaagccta gcacaaatag
     4561 tatatccaga catgtaaaac ctgcaaacag tagaagtggt aagaacgcat gggcaaagaa
     4621 aatcaagact agaagaggga aactatagcc cagcaagagc agaacgagga gaggacggta
     4681 gcgatcgacc agtttccacc ccataaactt cttggtaatg atatccctgc gcttcaataa
     4741 gaaagttgtt actagtaaga agtaggaaat catcatgcta aggagaccaa acaaagcaaa
     4801 gagtaggtta aaattccgaa cagcatctct ataagaatcc actttctctt gttgaatggc
     4861 ttgaatagat gaaaatttta aataatttcc atctgacaat ttctcaacta actctgtaat
     4921 ctctttttga tgttgaaccg tattttcaat tttaatcgga ttatttaagc cagttgttga
     4981 cagggaggct ttctcatccc acatcatatc agaatcattg accaagctaa taattggatt
     5041 ggagagattt tcctttcgct tatcactata tgggaaaaat gaccaatctc cttcataata
     5101 ggcaatctcg acatccatct cctctatcgt tcgtttttgc tgctcttcat acttcatcga
     5161 atgaaaggca attaacttcc ccaagagctg atttttatct tcttcacctt tcgtacttgc
     5221 tggcatcaaa ataacttttt taataccggt atctggtagc ttgaatccct tgctctttag
     5281 aaaattgcga ttggcatagt aaacatccac cgtatctgtt aactgatatt gccgaatctg
     5341 ttctgattgg acaaaatttt ttacaggaag actgctactc tgcacatagc ccgcctgcgt
     5401 tttttctacc aaatcctgat aaaatcgata gaaataatct gtagatttcc ctgaccctgc
     5461 tagctcttct tgccacagat tatcattgag tttgaaggtt tctaaggtca ggtaattacc
     5521 ttgacttacc cactgttgct gataagcaag ttctttgttt tcttgttcta gacttttgcc
     5581 taccccaatc agtaaggccg tcagtaaaat agttgtccct attttcatca cataattgaa
     5641 gatgagacca agtttgacag atgaaaaacc tttcaacatg gaactgactg tcattttctg
     5701 aatcatcagg taggtcagcc aactgatgaa caaatacaac tgtaaaagca gaaattggga
     5761 taagagtaaa cttggaaaca aaagttttgg cctgtagtcc agcactaaaa atagtcccaa
     5821 gtcaatgaca agacttccac ccaagagaag ataaaaatta gtctttacaa aaccagctaa
     5881 aatcgccctg ctttgaaaac caagtaactt ttgaaccccc actcgtttca tctccatcat
     5941 cggctgataa actgtcacta acacaagaag caaaatagcc aagacaaaaa caatggcaga
     6001 taaaagcaaa tctcgattta tgacttccac tgcacttttg taggtcggct ctagcaaggt
     6061 agcctggtct atcttgaaaa aatcgctcca tttctgtaca atcctatcct tgtccatctc
     6121 ttgtgtagaa gttatcgtat agcgaccatt taaactacga gatgtatcct tgatataggt
     6181 ttgaaaagtc ataagctgaa taggtttggc ttttagaaag gtcggaatcg taccaagttt
     6241 attggaaatt tctttattac tatagactcc ttcaccatct gtggtaaaat caagagaaga
     6301 aatcccaaac tcttggtagg ggaaggtatc tttatcaaaa acaccagact tgaccacctc
     6361 atcaccactg tctgttttga tgatggagac tttatactcc tttgatacat cctcaaaaaa
     6421 tcgaagaaca gacgctgcag gttcgttaat atctttcaaa tacaaatcca aagaatctac
     6481 agtctttccc atttcttgaa tccgaaccac ttctcgtgta tagtttacat taaaaacaaa
     6541 aaaagtggta cacagaagca ggagtaacat acagaaatta ctgatttttt tcataaaagt
     6601 gcctccacta cagttttccc tctccaaata ggagagggaa gaattttact caaatccata
     6661 gaaatattcc attcctgttg gcggaatctt ggtgagggaa gctctagccc atgcctcagg
     6721 ttttgcataa tccttagagg ttctaccccc atgtctaaca gttgctgtat gatatcgagt
     6781 agaatgtaag taatcagaat atccaaaagt tcctgtccaa cctactccat agttccattg
     6841 accaccctca acccatactg ctaaagcatt tgtagtagca agtataccac ataccattaa
     6901 agatgcaaca ccaattttaa ctaattttct catgatttat ttctcctatt atcgagagct
     6961 gttccgtaaa aacagctata gtaatttatc aacaagtatc gtagtccatt ggactcacct
     7021 tccttctatc tcatttcatt ttttaacaac gaacttactc ttaaccggga gaatggtgcg
     7081 cttctgtatc aggtccttga acaaccagag tagtattaag cacactctaa ctattactca
     7141 agaatcagtc caataaacaa tatggatagc gctttcaaat ttttaaactc ctatcccatc
     7201 cttttatcta tataataagt gaaaatataa taactgtcaa gtaact
//
LOCUS       DAVHBD010000065         7069 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000065 DAVHBD010000000
VERSION     DAVHBD010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7069
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.065"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(373..2064)
                     /locus_tag="VVK04_001937"
     CDS             complement(373..2064)
                     /locus_tag="VVK04_001937"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU3990553.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2200..2646
                     /gene="argR"
                     /locus_tag="VVK04_001938"
     CDS             2200..2646
                     /gene="argR"
                     /locus_tag="VVK04_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU3990554.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2697..5231
                     /gene="mutS"
                     /locus_tag="VVK04_001939"
     CDS             2697..5231
                     /gene="mutS"
                     /locus_tag="VVK04_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU3990555.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIAMVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGSKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5378..>7069
                     /locus_tag="VVK04_001940"
     CDS             5378..>7069
                     /locus_tag="VVK04_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990556.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         1925 a         1382 c         1663 g         2099 t
ORIGIN      
        1 tatttggtta ggtgaattag tgaagcgttt aggcaagtgt ctctggttac gacgtaaaga
       61 agcataaatc gataatattt atgtttcttt actagtgaaa cgcctagcca aattaccata
      121 gttacgacgt catggcctct aaatcgatta tatttagggg tcatgactag tgaagcagtt
      181 agctagttcg catataagcg gttagcgtct aacaattagg aactttagtt ccaataactt
      241 taagattacg acgttttagg acataaatcg atcatattta tgtcctaaaa ctagtgaagc
      301 gcctagccaa agtccgaata ggatttggcg ttagttactt agattgcttt gcaatcaagt
      361 aactttggcg atttacatct tctctggcgc ttctactcca agcaagcgaa gggcttcttt
      421 tagaacgact gcggttgcgt agctgagggc tagacggctg tcgcgttctg ggctttcatc
      481 caagatacgt gtatgtgcat agtatttgtt aaaggattga gctaggctaa ttgcaaattt
      541 agcaatgata gaaggttcaa agttatctgc cgcacggttg ataatacgtg ggaagtcttg
      601 aatgagttta atgatttccc agctttcagt atcattcaag ctatagttgc cagctgtttc
      661 tggtttgaaa tcggctttgc gtaagataga ttggatacga gcgtaggcat attgaacgta
      721 aggtccagtt tcaccctcga aggataccat agcttctagg tcgaagtcgt atccatttgt
      781 acggtcggtt ttgaggtcat agaatttaat ggctccaacc ccaacagcat gtgctacttg
      841 gtctttgttt tctagttcag gatttttagc ctcgatttgg accttggcac ggctaacagc
      901 ctctgcaaca gtaggctcta gcaagatgac attcccttta cgagtagaga gcttcttccc
      961 ttcctttgta accaaaccaa aaggaacgtg agtaatgtcg tcactccagt cgtagcccat
     1021 ctcttgcaag acagctttga gctgtttaaa gtgggcagat tgttcttgac caacgacata
     1081 gatagattta gcaaattggt attcgttttt acggtagagg gctgcagcca agtcacgtgt
     1141 gatatagaga gttgcaccat cagacttctt gatgagggct ggatgttcaa ttccatattt
     1201 ctcaagattc acaacttggg caccttctga ttcaagaagt agtccttttt cagaaagaat
     1261 gtctacaact gcatccatct tatcattgta gaaggcttct ccgttatagc tgtcaaattc
     1321 aaccttcaat tcattgtaaa ggcggttaaa ttccactaaa ctttcatcgc ggaaccattg
     1381 ccaaagagcg agagcttcct catctccatt ttcaagttta cggaaccatt cgcgcgcttc
     1441 ttcatccaag ctagggtcat tttcagcttc agcgttgatg cggacataga gtttaaggag
     1501 ttcatcgatt ggatgagctt ttacagcttc ttcgtcgccc cattttttgt aggcaacaat
     1561 caacatccca aattgtttac cccagtctcc caaatggttg accttgaccg tttgataacc
     1621 gattttttgg aaaatatgtg acaagctatc tccgataaca gttgaacgca ggtggccaat
     1681 agaaaatggt ttagcgatat tcggactaga catgtcgata acaacatttt cttgtttacc
     1741 aatattttgg tcagcatagt gttctttttc agtggtaaca gcttgcaata cttgagcaga
     1801 aatggcagat ttatcaagga aaaagttaac gtaaggtcct gttgcgacaa ctttttcaaa
     1861 ggcttggctg ttcatttttt cagccagttc agccgcaatc atttgtggtg ctttacgttc
     1921 gactttggca agagaaaaag cagggaaagc gatgtcaccc atttctgagt ttttaggggt
     1981 ttccagtaac tttaaaatag cctcttggtc caggctatca atgatgctag ccaattcgct
     2041 agcaatcaat tcttttgtat tcattaagag ctcctttttg gacttttcta ctattttatc
     2101 acaattttaa agaaagaaga aaaaattttt gaaatctcct gtttttttgg tataatatgg
     2161 ttataaatat agttataaat atgcacgcaa gaggatttta tgagaaaaag agatcgtcat
     2221 cagttaataa aaaaaatgat tactgaggag aaattaagta cacaaaaaga aattcaagat
     2281 cggttggagg cgcacaatgt ttgtgtgacg cagacaacct tgtctcgtga tttgcgcgaa
     2341 atcggcttga ccaaggtcaa gaaaaatgat atggtgtatt atgtactagt aaatgagaca
     2401 gaaaagattg atttggtgga atttttgtct catcatttag aaggtgttgc aagagcagag
     2461 tttaccttgg tgcttcatac caaattggga gaagcctctg ttttggcaaa tattgtagat
     2521 gtaaacaagg ataaatggat tttaggaaca gttgctggtg ccaatacctt attggttatt
     2581 tgtcgagatc agcacgttgc caaactcatg gaagatcgtt tgctagattt gatgaaagat
     2641 aagtaaggtc ttgggagtta ctctcaagac ttatttttga aaaggagaga cagaaaatgg
     2701 cgatagaaaa gctatcaccc ggcatgcaac agtatgtgga tattaaaaag caatatccag
     2761 atgctttttt gctctttcgg atgggtgatt tttatgaatt attttatgag gatgcggtca
     2821 atgctgcgca gattctggaa atttccttaa cgagtcgcaa caagaatgcc gacaatccga
     2881 tccctatggc gggtgttccc tatcattctg cccaacagta tatcgatgtc ttgattgagc
     2941 agggttataa ggtggctatc gcagagcaga tggaagatcc taaacaagca gttggggttg
     3001 ttaaacgaga ggttgttcag gtcattacgc cagggacagt ggtcgatagc agtaagccgg
     3061 acagtcagaa taattttttg gtttccatag accgcgaagg caatcaattt ggcctagctt
     3121 atatggattt ggtgacgggt gacttttatg tgacaggtct tttggatttc acgctggttt
     3181 gtggggaaat ccgtaacctc aaggctcgag aagtggtgtt gggttatgac ttgtctgagg
     3241 aagaagaaca aatcctcagc cgccagatga atctggtact ctcttatgaa aaagaaagct
     3301 ttgaagacct tcatttattg gatttgcgat tggcaacggt ggagcaaacg gcatctagta
     3361 agctgctcca gtatgttcat cggactcaga tgagggaatt gaaccacctc aaacctgtta
     3421 tccgctacga aattaaggat ttcttgcaga tggattatgc gaccaaggct agtctggatt
     3481 tggttgagaa tgctcgctca ggtaagaaac aaggcagtct tttctggctt ttggatgaaa
     3541 ccaaaacggc tatggggatg cgtctcttgc gttcttggat tcatcgcccc ttgattgata
     3601 aggaacgaat cgtccaacgt caagaagtag tgcaggtctt tctcgaccat ttctttgagc
     3661 gtagtgactt gacagacagt ctcaagggtg tttatgacat tgagcgcttg gctagtcgtg
     3721 tttcttttgg caaaaccaat ccaaaggatc tcttgcagtt ggcgactacc ttgtctagtg
     3781 tgccacggat tcgtgcgatt ttagaaggga tggagcaacc tgctctagcc tatctcatcg
     3841 cacaactgga tgcaatccct gagttggaga gtttgattag cgcagcgatt gctcctgaag
     3901 ctcctcatgt gattacagat gggggaatta tccggactgg atttgatgag actttagaca
     3961 agtatcgttg cgttctcaga gaagggacta gctggattgc tgagattgag gctaaggagc
     4021 gagaaaactc tggtatcagc acgctcaaga ttgactacaa taaaaaggat ggctactatt
     4081 ttcatgtgac caattcgcaa ctaggaaatg tgccagccca ctttttccgc aaggcgacgc
     4141 tgaaaaactc agaacgcttt ggaaccgaag aattagcccg tatcgaggga gatatgcttg
     4201 aggcgcgtga gaagtcagcc aacctcgaat acgaaatatt tatgcgcatt cgtgaagagg
     4261 tcggcaagta catccagcgt ttacaagctc tagcccaagg aattgcgatg gttgatgtct
     4321 tacagagtct ggcggttgtg gctgaaaccc agcatttgat tcgacctgag tttggtgacg
     4381 attcacaaat tgatattcgg aaagggcgcc atgctgtcgt tgaaaaggtt atgggggctc
     4441 agacctatat tccaaatacg attcagatgg cagaagatac cagtattcaa ctgattacag
     4501 ggccaaacat gagtgggaag tctacctata tgcgtcagtt agccatgacg gcggttatgg
     4561 cccagctggg ttcctatgtt cctgctgaaa gcgcccattt accgattttt gatgcgattt
     4621 ttacccgtat cggagcagca gatgacttgg tttcgggtca gtcgaccttc atggtggaga
     4681 tgatggaggc caataatgcc atttcgcatg cgaccaagaa ctctctcatt ctctttgatg
     4741 aattggggcg tggaactgca acttatgacg ggatggctct tgctcagtcc atcatcgaat
     4801 atatccatga gcacatcgga tctaagaccc tctttgcgac ccactaccat gagttgacta
     4861 gtctggagtc tagtttacaa cacttggtca atgtccacgt ggcaactttg gagcaggatg
     4921 ggcaggtcac cttccttcac aagattgaac cgggaccagc tgataaatcc tacggtatcc
     4981 atgttgccaa gattgctggc ttgccagcag accttttagc aagggcggat aagattttga
     5041 ctcagctaga gaatcaagga acagagagtc ctcctcccat gagacaaact agtgctgtca
     5101 ctgaacagat ttcactcttt gatagggcag aagagcatcc tatcctagca gaattagcta
     5161 aactggatgt gtataatatg acacctatgc aggttatgaa tgtcttagta gagttaaaac
     5221 agaaactata aaaccaagac tcactagtta atctagctgt atcaaggaga cttctttgac
     5281 aattctccac ttttttgcta gaataacatc acacaaacag aatgaaaagg agctgacgca
     5341 ttgtcgctcc cttttgtcta ttttttaagg agaaagtatg ctgattcaga aaataaaaac
     5401 ctacaagtgg caggccctgg cttcgctcct gatgacaggc ttgatggttg ctagttcact
     5461 tctgcaaccg cgttatctgc aggaagtctt aggcgccctc cttactggga aatatgaagc
     5521 tatttatagt atcggggctt ggttgattgg tgtggccgta gtcggtctag ttgctggtgg
     5581 actcaatgtt gtcctcgcag cctatattgc ccaaggagtt tcatccgacc ttcgggagga
     5641 tgccttccgt aaaattcaaa ccttttctta tgctgatatt gaacaattta atgcgggaaa
     5701 tctagtcgtt cgaatgacaa atgatatcaa ccagattcag aacgttgtca tgatgacctt
     5761 ccaaattctt ttcagacttc ccctcttgtt catcggttcg tttatcctag cggttcaaac
     5821 cttaccttct ctgtggtggg tgattgttct catggtagtc ttgatttttg gtttgactgc
     5881 tgtcatgatg ggaatgatgg ggcctcgttt tgctaaattt caaacccttc ttgagcgcat
     5941 caatgccatt gccaaggaaa atttacgtgg cgttcgtgtg gtcaagtcct ttgtccaaga
     6001 aaaagagcaa tttgctaagt ttacagaggt ctcaaacgag cttcttggtc aaaaccttta
     6061 cattggttat gccttttcag tagtggaacc ctttatgatg ttggttggtt acggggcggt
     6121 cttcctctct atttggctgg tcgcgggaat ggttcagtcg gatccgtctg ttgttggttc
     6181 catcgcttct tttgttaatt acctaagcca gattatcttt accattgtta tggttggatt
     6241 tttgggaaat tctgtcagcc gtgccatgat ttccatgcgt cgtattcgag aaattcttga
     6301 cgcagagcca gctatgacct tcaaggatat cccagatgaa gagttggttg gaagtcttag
     6361 ctttgaaaat gtgaccttta cctatccaat ggacaaggaa ccgatgctga aagatgtgag
     6421 ctttactatt gaacctggtc aaatggttgg tgtagttgga gcgactggtg caggaaagtc
     6481 aaccttggct caattgattc cacgtctctt tgatccacag gacggggcca ttaaaatcgg
     6541 tggcaaggat attcgagaag tgagtgaagg aaccctgcgt aaaacagttt ccatcgttct
     6601 ccaacgtgcc attcttttta gtggaacgat tgcagataac ttgagacagg ggaagggaaa
     6661 tgctacctta tttgaaatgg agcgcgcagc caatattgcc caggctagtg aattcattca
     6721 tcgtatggag aaaacctttg aaagtccagt tgaagaacgg ggaaccaatt tctctggtgg
     6781 acaaaaacaa aggatgtcga ttgcgcgtgg gattgtcagc aatccacgta ttctgatttt
     6841 tgacgattcg acctcagcct tggatgccaa atcagagcgc ttggtgcaag aagctttgaa
     6901 taaggatttg aagggtacga caactattat tattgctcaa aaaattagct cggttgtcca
     6961 tgcagacaag atcttggttc taaatcaagg acgattgatt ggtcaaggca cgcatgcaga
     7021 cttggttgcc aacaatgccg tttaccgtga aatctatgaa acacagaaa
//
LOCUS       DAVHBD010000066         7037 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000066 DAVHBD010000000
VERSION     DAVHBD010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7037
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.066"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(116..391)
                     /locus_tag="VVK04_001941"
     CDS             complement(116..391)
                     /locus_tag="VVK04_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU3990557.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(498..1337)
                     /locus_tag="VVK04_001942"
     CDS             complement(498..1337)
                     /locus_tag="VVK04_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU3990558.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1479..2327
                     /locus_tag="VVK04_001943"
     CDS             1479..2327
                     /locus_tag="VVK04_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU3990559.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2420..3337)
                     /locus_tag="VVK04_001944"
     CDS             complement(2420..3337)
                     /locus_tag="VVK04_001944"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU3990560.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3774..3979
                     /locus_tag="VVK04_001945"
                     /pseudo
     CDS             3774..3979
                     /locus_tag="VVK04_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4290..4583)
                     /gene="rpmA"
                     /locus_tag="VVK04_001946"
     CDS             complement(4290..4583)
                     /gene="rpmA"
                     /locus_tag="VVK04_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU3990561.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4600..4944)
                     /locus_tag="VVK04_001947"
     CDS             complement(4600..4944)
                     /locus_tag="VVK04_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU3990562.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4960..5274)
                     /gene="rplU"
                     /locus_tag="VVK04_001948"
     CDS             complement(4960..5274)
                     /gene="rplU"
                     /locus_tag="VVK04_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU3990563.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5310..5397)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5456..6160)
                     /locus_tag="VVK04_001949"
     CDS             complement(5456..6160)
                     /locus_tag="VVK04_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU3990564.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6562..6861
                     /locus_tag="VVK04_001950"
     CDS             6562..6861
                     /locus_tag="VVK04_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU3990565.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2226 a         1422 c         1171 g         2218 t
ORIGIN      
        1 atacaatatt ttcggaacat tcaacttttt aactctattt attactagat ttcataatta
       61 aaaagcctac tgaccaagct agaaagcttg atacaatagg ctttttaaag actgattatt
      121 taacagcgtc tttaagagct ttaccagctt tgaatgctgg cactttagaa gctgcaattg
      181 tcatttcttt accagtttgt gggttgcgac ctttacgttc tgcgcgctca cgaacttcaa
      241 agttaccaaa accgatcaac tgaacttttt caccagctgc aagatagtca gctactgctg
      301 caaatacagc ttcaactgct gctgctgagt ctttcttagt caattctgta gcttctgcta
      361 ctttagcgat caaatcttgt ttgtttgcca tgttaatgat tcctccaaat aatttctaat
      421 taacaaatat aatcatatcc taaaatccct tttaggtcaa gttaaaaacg ctatttcttc
      481 ccattttatt tattttttta ggagtggtaa cgtatcaaaa tagcccaagc gttctcaccc
      541 gtgtgagttt gaataatgga acccgtttcc aaaacagaaa ttggcttttc aacataagct
      601 tgtaagcttt ctttcatctc ttttgcccaa tcatcactac cagaatatga aattccaatc
      661 tctgctacag cacgttcaga aagcgatgtt atcaactcat ctaaccattt tttaaatgtt
      721 ttagttccac gacctttaac cattggctgc aattcatggt ctttcatttg catgacaaca
      781 cggatattga gaagagagct caacaagcca gttacacggc taattcgtcc acctttgaca
      841 agattttcca aagttgaaac accaatataa agctctgtat ggtttttaac ctcttctaca
      901 tgagataaaa ttgcctccat atctttacct tcttgagcta acttcgcagc ctcaacaact
      961 tggaatttca gggcttggtc agtgaaggaa ctatcaacaa cagtcacatc tgcagtagat
     1021 aggctagcac cttggcgtgc tgcttctacc gtacccgaaa gagcatggga catatgaata
     1081 gcaagaatct ggccaccatc tttgcatagg tcttcaaaaa tctcagcaaa gacacctaca
     1141 ggtggctgac ttgttttcgg aagattctta ctttcttgca tcaactgaag aaatttacct
     1201 tcttctttca aatccgcatc agaataaaca acattatcaa tcattacaga taatggaaca
     1261 attgtaatat ctaattgctt tactagttca ggttcaatag taacagatga atcggttaca
     1321 atcttaattt ttgtcatagt atcaatcttt ctattttagg attcagattg gtttccttac
     1381 ttctaattat atcaaaaaaa agattaaaaa tcctaatgga gtcaatcaaa ttttccgtaa
     1441 aatttgatat aatcaactta taagaaaaga ggtgtcctat gattaaaaaa atttacccca
     1501 tttttaccat tttactaggt gctgctattt atgcttttgg actgacttat tttgtagttc
     1561 cccatcatct ctttgaagga ggggcgacag gcattaccct catcaccttt tatcttttta
     1621 aaatccctgt ttccctcatg aacctgctga ttaatattcc ccttttcatc ctagcttgga
     1681 agatctttgg agccaaatcc ctctattcta gtttactagg aaccttagct ttgtccgcct
     1741 ggttagcttt ttttgagcat attccccttc atattgatct tcaaggtgat ttactaatca
     1801 cagcccttat agcgggaatc ctattgggaa ttggccttgg aattattttt aatgctggag
     1861 gtacaactgg cggaactgat attctagctc gtattctcaa caaatacact catatatcca
     1921 taggaaaact gctctttatc ttagattttt gtattctcat gttgattctc ctaatcttca
     1981 aggatttgag attggtttcc tacacgcttt tgtttgattt tattgtttct cgtgttattg
     2041 atttgattgg tgaaggagga tatgccggca aaggctttat gattatcaca aaacgtcctg
     2101 accaacttgc taaggcgatt aatgatgacc tcggaagagg tgttactttt atttctggtc
     2161 aaggctacta tagtaaagaa aatttgaaaa tcatctactg tattgtcgga agaaatgaaa
     2221 ttgtgaaaac gaaggaaatg attcatcgaa tcgatcctca agcctttata actattacag
     2281 aagcccatga aatcctagga gaaggcttca cctttgaaaa agaataaaaa gaggtaatgt
     2341 cgtgacctca aaagttagac taaatcatct atcttttggg ttacagacaa cctctttttt
     2401 gttttattta ctcaagctct taagaccaat tccgagttac ttcttcatca gcctttaact
     2461 gatccactaa ttggtcaact gagtcaaatt tggtcatatc acgaatgcga tcaagccaat
     2521 aaaccatgac ggtttcccca taaatatctt gattaaaatc aaaaatattg acttcaaaac
     2581 gtgcttcttc tccatcaaag gtcacatttt tcccgacact agccatagca cgatacttct
     2641 gtctttgaat ctcaacatca acgacataaa cgccatctgc tggcatataa gtacggtcta
     2701 aaagcactaa attcgctgtc ggataaccaa ttgtacgacc acgagcatta ccatgaacca
     2761 ccatacctct tgatggaagc ggtgccccca aaagttttcc tgcttctttc acatttccat
     2821 ctaaaatagc ttgacggata cgagttgaac taatctttcc tttctcatct tctacaggtg
     2881 gaacaatgat aacttctcca tcaaagtaat cctttaaatc ttctgctgtt tttttgtcag
     2941 aaccaaatgt ataatcaaaa cctgcaacaa taattttggc attcatagcc ttgatataag
     3001 ttgcaaagaa ttcttgtgca gtgagactag cgaattgact actaaaatca aggagatata
     3061 attcttctac accttcgcgc tttaattttc tttcacgttc agcagggttc aaaatatgca
     3121 aaaacaaatc tggatgataa ggctctaaag cgatctttgg agattcatta aaggtcataa
     3181 cgacgatagg caataaatcc tttctcgcag ccttgttggc aacacgaaat aattcttgat
     3241 gccccttatg tatgccatca aaatagccga gaacaacgac tgaatcagat ggtgtgccaa
     3301 tatctttttg gttttttata ggaatagtaa taatcataaa ataattatat catagcgata
     3361 gctatttctg gaacagaaaa tctgaaatgt tgtttttttc acatgaagtg tacctgtttt
     3421 caaaaagcac tttattctat cgttgcttaa ctatgaactt tgcaatattc ttctcaaaaa
     3481 cttgtaggac atcttcaaaa ttttgcaagg agtgattaga cttgttcggt aaccataaag
     3541 tgtcatacta tgttatgtat gaaaaagcaa tgcaactaac tcctgagaac tttaaattac
     3601 taattggtgc cgaaaaggta gaatttagaa tcgaggtaca cctatggctg taaaatttac
     3661 aaaatgagac aacttgggca agatgtttga agaatttcct aaactccctg atttgaagca
     3721 agtcactttc cctgatgaca aagaaaaaag ccaaaacagc aaagaaaaac tagatgactg
     3781 ctttccaaca actcccatct agtgtgcttc agactgggct atttttctct ccatctgtta
     3841 gcttggattc tcagaccgtt tcagctaaag aatatctttt cccttatcag aaggaacggc
     3901 tcaaaccatt cagacaagtg aagggacgac aagccaatat ttgaaaccag atagcagttc
     3961 ttatagtcaa ttgaaataaa atctgaagaa atcgagtagg aaactcatat caatttttaa
     4021 cagtgttcta ttccagattc atactcaatg aaaattaaag tgcaaactag gaagttagcc
     4081 gcaggctgta cttgagtacg gcaaggtgaa attgacgtgg tttgaatttg attttcgaag
     4141 agtatcaatc cactatacat attaaaaagt atgggtatca aaataaaaaa acaggctctc
     4201 cgaaaactcg gaaagcctta ttttaagctg tttctagctt cctcaccttt acatttcaag
     4261 gttcgggata aaaggttcaa tgaacctttt tattttgcga ttgggtaaac agaaacttgt
     4321 tttttatcgc gtcctttacg ttcaaagcgt actacgcctt caactttagc gaacaaagta
     4381 tcgtctccac cacgaccaac gtttacacct ggatagatgt gtgtaccacg ttgacggtaa
     4441 aggattgatc cacctgttac agtttgtccg tcagctgctt tagctccaag acgttttgct
     4501 tgtgaatcac gtccgtttga tgtagaacct ccaccttttt tgtgggcgaa aagttgcaag
     4561 ttgttaagag tcatttttaa cataatgttt tcctccgtgt tagttttctg tgataactct
     4621 ggtttggacg aactcagaat agttctccga taagtttgcc atacctaaga aaaatgattc
     4681 aaagaataac tgggtcattt ctctctggtg tgaaggaaga tcttttggta tttcaaccat
     4741 cagatagcca ccttcatctt cgtttaattc taggattggt tcatagcctg caaatttctc
     4801 aatagaattg ataaagttaa tggcaagcgt agaaaccgat gcacacacga catctaagcc
     4861 gtattcgcca ctctcggcgt gtccagtaat ttccgcactc ctcagctcgc catcttcggc
     4921 tctctcaaag actgcctgta tcatgtgttc tccttaaaat taagcgttga ttgcgttgat
     4981 gacaactttt gtatatggtt gacggtgacc ttgtttacgg tggctacctt ttttaggttt
     5041 gtacttgtaa gtaaccactt tcttttgttt tccttgtttt tcaacagttc caactacagt
     5101 agctccagca acaagtggag ttccgacaac agtgttttca ccaccaacaa gaacaacttc
     5161 gttaaaagta acttcttgac cagcttcaac gttcaatttt tcaacgtaaa ctgcttgacc
     5221 aacttcaact ttaacttgtt ttccgccagt tttgataatt gcgtatgtgc tcattatgca
     5281 cctcctatga tttttatggg tttccccgat tttttgtgaa gactcgccta gcatcgtggg
     5341 acgaaccact taaacttgaa taatcaagca acgatgttcg tgcggttgca caggatcgtg
     5401 catagtcaac tcttcaagta tagcatatct cctattttct tacaagtaat aacacctaaa
     5461 atgaagcttt ttcttttact tttttctgcc aagaggcaaa aagcatgctg aggtaaaaaa
     5521 cgctcatcat aataggaaca ccaagaatgg tcttttcatg atagaaaatc gtcaaatagg
     5581 ctgaaaagac aacgccaagg acaaaactac taagcaggct aacaaatatg aatccttcac
     5641 gcaaaaaagg agtgtgcttg gttcggaaat aatctccaaa agccagcatg gtccgtttga
     5701 tattccctgt cataaaagcg ttattatagg caatacccga cacttctcca aaagcagttg
     5761 tcaccagtcc catacagaag gccaagggcg gcactagata gatattatcc acagtttgcg
     5821 gcacaaaagc aataatgatt gataagattg ccaagggaat caaggacaga ataggttttt
     5881 tcacaattct caatttttcc ttataaatcg ttaataaaaa gactcccatc ataaacgcta
     5941 gcaaggtgag aaccttgtcc ctaacatccg aaacattatt tttaattaat tctactgaaa
     6001 gaaagacaac atttccagtt tgtccagcta caagggtatt cccgcgaaca ataaaagtgt
     6061 aagcatccac atatccagca caaaacgtca aaaaaagtgc taacctttta gactgacgtg
     6121 atatttttct tataggtaat aacctcattt tacctcccat tgtattttct cttagaaata
     6181 ttgtaccatt ttctttctaa aaaatcgtag gctaccattt agattttact attagcataa
     6241 aaataataat agacaactat ttatccaaaa atagatagat gtaacatgtt tgcaaacaaa
     6301 gcatacgaac ctttagtaaa atcatttcca tgaaactaga atagagccct cttagcaaaa
     6361 atcattattt taatttattt ctaatcactc cttgacataa ataactctca ccaataaaag
     6421 actatgtctt aaaaaaatgg tataataaaa tcaatacttg ggcttgatgg ctatgctact
     6481 aataacaatt aggagagaaa atcaggtact tgttaacaac aaggattatc cccttgagat
     6541 gaaaggaact ttagaaatct tatgatgaac atgcaaaaca tgatgcgtca agcacaaaaa
     6601 cttcaaaaac aaatggaaca aagccaagct gaacttgctg ctatgcaatt tgttggcaaa
     6661 tctgctcaag atcttgtcca agcgacctta actggcgata agaaagttgt cagcattgat
     6721 ttcaatccag ctgtcgttga cccagaggac cttgagactc tttctgatat gaccgttcaa
     6781 gccatcaact ctgctcttga acaaatcgat gaaactacca agaaaaaact gggtgctttc
     6841 gctgggaaat tacctttcta aaaacaagga gctagaacaa tgcttgtcga taacaaaggc
     6901 taagaaaggt gcaaaaatga ctctataata tttgtagtgg gtaaatccac tatagatatt
     6961 atggagctta tttttgtgta gaaaaaaagt cccatatgac ctataatgaa aagcgacaaa
     7021 acaactcatt agaaaga
//
LOCUS       DAVHBD010000067         6700 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000067 DAVHBD010000000
VERSION     DAVHBD010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.067"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(56..319)
                     /locus_tag="VVK04_001951"
                     /pseudo
     CDS             complement(56..319)
                     /locus_tag="VVK04_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            517..2283
                     /gene="patB"
                     /locus_tag="VVK04_001952"
     CDS             517..2283
                     /gene="patB"
                     /locus_tag="VVK04_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU3990566.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFK"
     gene            2422..3111
                     /locus_tag="VVK04_001953"
     CDS             2422..3111
                     /locus_tag="VVK04_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU3990567.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            3115..3294
                     /locus_tag="VVK04_001954"
     CDS             3115..3294
                     /locus_tag="VVK04_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990568.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3281..4630
                     /locus_tag="VVK04_001955"
     CDS             3281..4630
                     /locus_tag="VVK04_001955"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU3990569.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4754..6214
                     /locus_tag="VVK04_001956"
     CDS             4754..6214
                     /locus_tag="VVK04_001956"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU3990570.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELVAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6228..6662
                     /locus_tag="VVK04_001957"
     CDS             6228..6662
                     /locus_tag="VVK04_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU3990571.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNEQ"
BASE COUNT         2093 a         1295 c         1445 g         1867 t
ORIGIN      
        1 aggtcttgaa agcaggtgaa aagcgagggc atgctttggc agcttgtatg agtacctacc
       61 gcagatgagg ggaaccccgt ttgaccattc ttcctgctaa atcaatctga cctgactgat
      121 aaatagaaga atccagtcca gcgaaagctt gtaattgagc aggattatca aaggcatgaa
      181 tatttcgaat ctcggctaaa atgaccgccc ctaaacgatc cccaatccca gtaaccgtcg
      241 tgatgaccga gttgaactca gccatcaagt cattgacaca ttttttcgcc ttgtcaatga
      301 gcctcttgta atgtttgatg ttttcattac acgagataaa acgtctatgc gttatcaaac
      361 tcattaccaa ttaaaacaaa aagctgtggt tagatccttt cggaaattgt caagcgattg
      421 gaggaaatga actaatccac agcggcttat tccaagtata ccacttgggc tttggcagta
      481 gctaactgcg ctaaatataa tataaggagg agtaaaatga agacagttca atttttttgg
      541 cattatttta aggtctacaa gttctcattt gtagttgtca tcctgatgat tgttctggcg
      601 acttttgccc aagccctctt tccagtcttt tctggacaag cggtgacgca gctagccaat
      661 ttagttcaag cttatcaaaa tggcaatcca gaacttgtat ggcaaagcct atcaggaatc
      721 atggtcaatc ttggcctgct ggttttggtt ctatttatct ctagtgtaat atacatgtgt
      781 ctcatgacgc gcgtgattgc agaatcgacc aacgagatgc gcaaaggcct ctttggtaag
      841 cttgctcagt tgacggtttc tttctttgac cgtcgacaag atggcgatat cctgtctcat
      901 tttaccagtg atttggataa tatcctccaa gcctttaacg aaagcttgat tcaggtcatg
      961 agcaatattg ttttatacat tggtctgatt cttgtcatgt tttcgagaaa tgtgacgctg
     1021 gctctcatca ccattgccag caccccattg gctttcctta tgctgatttt catcgtgaaa
     1081 atggcacgca aatacaccaa cctccagcag aaagaggtag ggaagctcaa cgcctatatg
     1141 gatgagagca tctcaggcca aaaagccgtg attgtgcaag gaattcaaga ggatatgatg
     1201 gcaggatttc ttgaacaaaa tgagcgcgtg cgcaaggcaa cctttaaagg aagaatgttc
     1261 tcaggaattc ttttccctgt catgaatggg atgagcctga ttaatacagc catcgtcatc
     1321 tttgctggtt cggctgtact tttgaatgat aagtctattg aaacaagtac agccctaggt
     1381 ttgattgtta tgtttgcaca attttcacag cagtactacc agcctattat ccaagttgca
     1441 gcgagttggg gaagccttca gttggccttt actggagctg aacgaattca ggaaatgttt
     1501 gatgcagagg aggaaatccg acctgaaaag gctccaacct tcactaagtt gcaagaaagt
     1561 gttgaaatca gtcatatcga tttttcatac ttgcctgata aacctatttt gaaagatgtc
     1621 agcatttctg cccctaaagg ccagatgaca gcagttgttg ggccgacagg ttcaggaaaa
     1681 acgactatta tgaacctcat caatcgcttt tatgatgttg atgctggtgg tatttatttt
     1741 gatggtaaag acattcgtgg ctatgattta gatagtctta gaagcaaggt gggaattgta
     1801 ttgcaagatt cggtcttgtt tagcggaacg attcgagaca atatccgatt tggtgtgcca
     1861 gatgctagtc aggaaatggt tgaggtagca gcaaaagcaa cccacattca cgactatatc
     1921 gaaagtttgc ctgataagta cgatactctt attgatgatg accagagcat cttttcaaca
     1981 gggcagaagc aattgatttc aatcgctcga accctgatga cagatccaga agttctcatt
     2041 ctcgatgaag caacttcaaa cgtagatacg gtgacagaaa gcaagattca gcatgccatg
     2101 gaggtggttg tagcaggtag aactagtttc gtcattgccc accgcttgaa aaccattctc
     2161 aatgcagatc agattattgt ccttaaagat ggagaagtca ttgaacgtgg taaccaccat
     2221 gaacttttga agctaggtgg cttttattca gaactctatc acaatcaatt tgttttcaaa
     2281 taagaaagaa gttgtcctat gtgggcagct ttttcttgtc cataaaaaat gtttatcaca
     2341 gccttaaaaa aaacatatta gacgaaagtc attttgagtg atatgatagg actatcgtta
     2401 gcattcgaaa ggagaggcat catggctaga acggttgtag gagttgctgc aaatctatgt
     2461 cccgtagacg cagaaggcaa aatcattcat tcatctgtat cttgtagatt cgcagagatc
     2521 attcgtcaag tcggtggtct ccctttagtc attcctgttg gtgatgagtc agttgtacgt
     2581 gattatgtgg aaatgattga caaactcatt ttgacaggag gccaaaatgt tcatcctcag
     2641 ttttatggag agaaaaagac cgtcgaaagc gatgattaca atctggtccg tgacgaattt
     2701 gaattggcac tcttgaagga agcgcttcgt cagaataaac caattatggc aatctgtcgc
     2761 ggtgtccaac ttgtcaatgt tgcctttggt ggaaccctca atcaagaaat cgaaggtcac
     2821 tggcaaggac tacctttcgg gacatctcac tctattgaga cagtagaagg aagcgtggtg
     2881 gctaagctat ttgggaaaga aagtcaggtc aactcagtcc atcgtcaaag cattaaagat
     2941 ttggcaccta atttccgtgt aactgctatt gattcaagag accaaactat tgaagcgatt
     3001 gagtctatcg acgagcaccg cattatcggt ttacagtggc atccagagtt tctggttaat
     3061 gaagaagatg gcaatttaga attatttgag tatttattga atgaactgta acgattggaa
     3121 catctggtcg ttctttcttt tattttttca aaatttttag aatgtggcat tttacgcaaa
     3181 cgtttgaatt ctgataaaaa ttggagaaat tcgacaaaaa aacttgaaaa aaacgaaggt
     3241 aagcgttatg atagaaaaga agaaatattg gaggaagaac atgtcacata ttaaatttga
     3301 ttattcaaaa gttttagaca aatttgttgc accacatgaa gtggaataca tgcaatcaca
     3361 agtaacagca gcagatgaat tgatccgtaa aggaactggt gctggtagcg acttcttggg
     3421 atggttggac cttcctgaaa aatacgatcg cgaagaattt gaccgcatct tgaaagctgc
     3481 tgagcaaatc aagtcagaca gcgatgtttt ggttgtgatc ggtattggtg gatcttacct
     3541 tggtgcaaaa gcagcaatcg acttcttgaa tcaccatttt gctaacttgc aaacaaaaga
     3601 agaacgcaaa gctccacaaa tcctttacgc aggaaactca atctcatcta cttaccttgc
     3661 tgacttggta gagtatgttg cagacaaaga cttctcagta aacgtaattt ctaaatcagg
     3721 tacaacaact gaaccagcga ttgctttccg tgtctttaaa gaactcttgg ttaagaaata
     3781 cggtcaagaa gaagctaaca aacgtatcta tgcaacaact gaccgccaaa agggtgctgt
     3841 taaggttgaa gcagacgcta acggttgggg aacatttgtt gttccagatg atatcggtgg
     3901 acgcttctca gtattgacag ccgttggttt gcttccaatc gcagcatcag gagctgacat
     3961 caaagctctt atggaaggtg cgaatgcagc tcgcaaagac tacacttcag acaaaatctc
     4021 tgaaaacgaa gcttaccaat acgcagctgt tcgtaacatc ctttatcgta aaggctatgc
     4081 aactgagatc ttggtaaact atgagccatc acttcaatac ttctcagaat ggtggaaaca
     4141 attggctggt gaatcagaag gaaaagacca aaaaggtatc tacccaactt cagccaactt
     4201 ctcaactgac ttgcactcac ttggtcaatt tatccaagaa ggaactcgta tcatgtttga
     4261 aacagttgtc cgtgttgaca aacctcgtaa aaacgtgctt attcctactt tggaagaaga
     4321 ccttgacgga cttggttacc ttcaaggaaa agacgttgac tttgtaaaca aaaaagcaac
     4381 tgacggtgtt cttcttgccc acacagatgg tgatgtacca aacatgtatg tgactcttcc
     4441 agagcaagac gctttcactc ttggttacac tatctacttc ttcgaattgg caattgccct
     4501 ttcaggttac ttgaatgcta tcaacccatt tgaccaacca ggtgttgaag cttataaacg
     4561 taacatgttt gcccttcttg gaaaaccagg atttgaagaa ttgagcaaag aacttaacgc
     4621 acgtctataa tagaagaaaa gagtggtttg cccactcttt ttactctctt tatccataga
     4681 aattggactc agccaagact tgtgatataa tatagaaagc aaaaaggcag acgcctagat
     4741 aataggagaa actatgtcaa aagatatccg cgtacgttac gcaccaagtc caacaggact
     4801 actacacatc ggaaatgctc gtacagcatt gtttaattac ttgtatgcgc gccatcatgg
     4861 tggaacattt ctcatccgta tcgaagatac tgaccgtaaa cgccatgtcg aggatggtga
     4921 acgttcacaa cttgaaaacc ttcgctggtt aggcatggat tgggatgaaa gtccagaatc
     4981 acatgagaat tatcgccagt ctgagcgttt ggacttgtat caaaaataca tcgaccaact
     5041 attagctgaa ggaaaagcct acaaatctta cgttacagaa gaagagttgg tagctgaacg
     5101 tgaacgtcaa gaagtagctg gcgaaacacc acgctacatc aatgaatacc ttggtatgag
     5161 tgaagaagaa aaagcagctt acatcgcaga acgtgaagca gcagggatca tcccaactgt
     5221 tcgtttggct gtcaatgagt caggtatcta caagtggcat gatatggtca aaggcgatat
     5281 cgaatttgaa ggtggcaata tcggtggtga ctgggttatc caaaagaaag acggttaccc
     5341 aacttacaac tttgccgttg ttatcgatga ccacgatatg caaatctctc atgttatccg
     5401 tggagatgac catattgcta atacaccaaa acagcttatg gtctatgaag ctcttggttg
     5461 ggaagctcca gagttcggtc acatgacctt gattatcaac tctgagactg gtaagaagtt
     5521 atctaaacgt gatactaata cacttcaatt tatcgaagat taccgaaaga aaggttacct
     5581 tccagaagca gtctttaatt ttattgctct tcttggttgg aacccaggtg gtgaagatga
     5641 gattttctct cgtgaagaac tcattaaact ttttgatgaa aaccgcctca gcaagtcacc
     5701 agcagccttt gatcagaaaa aactagactg gatgagcaat gattatatca agaatgcaga
     5761 ccttgaaacc atctttgaaa tggcaaaacc attcttagag gaagcaggcc gtttgactga
     5821 caaggctgaa aaattagttg agctctataa accacaaatg aaatcagtag atgagattat
     5881 cccattgaca gatcttttct tctcagattt cccagaattg acagaagcag agcgcgaagt
     5941 catgacgggt gaaacagttc caacagttct tgaagcattc aaagcaaaac ttgaagcgat
     6001 gacagatgat aaatttgtga cagaaaatat cttcccacaa attaaagcag ttcaaaaaga
     6061 aacaggtatt aaagggaaaa atcttttcat gcctattcgt atcgcagttt caggcgaaat
     6121 gcatgggcca gaattaccag atacaatttt cttgcttgga cgtgaaaaat caattcagca
     6181 tatcgaaaac atgctaaaag aaatctctaa ataaagagga tacaataatg gacatctggg
     6241 aaaagatgta cgaagaagca cagaaactat acaatccaca tgaagtatca gactttgttt
     6301 atgccaatca tgttgtagct gcagtagaag cagaagatgg acaaatattt acaggattct
     6361 gtatggaggg aacctgtggt gttttccatc tctgcgcaga acgggcggcc ctcttcaata
     6421 tgtaccaatt ttcaggacaa actaaggtta agaaagtatt agcctttcga gataaaccac
     6481 cttatggtgg aagttcagcc atgccttgcg gtgcttgtag agaattcctt ttagagctta
     6541 atgctgaaaa taaagatgca gaattcatga tggactataa tataagaaaa acagttaaag
     6601 tcgcagaact aatcccttat tggtggggag aagaacgtgc ttctaagttt aatgagcaat
     6661 agaagagtca gtataattct ggctcttttt actataagtt
//
LOCUS       DAVHBD010000068         6680 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000068 DAVHBD010000000
VERSION     DAVHBD010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.068"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..258
                     /locus_tag="VVK04_001958"
     CDS             <1..258
                     /locus_tag="VVK04_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990572.1"
                     /translation="WFQKFLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLP
                     PYSPEYNLIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            461..1294
                     /locus_tag="VVK04_001959"
                     /pseudo
     CDS             461..1294
                     /locus_tag="VVK04_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857688.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            1471..2478
                     /gene="gap"
                     /locus_tag="VVK04_001960"
     CDS             1471..2478
                     /gene="gap"
                     /locus_tag="VVK04_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU3990573.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2546..3382)
                     /locus_tag="VVK04_001961"
     CDS             complement(2546..3382)
                     /locus_tag="VVK04_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU3990574.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3508..5703
                     /locus_tag="VVK04_001962"
     CDS             3508..5703
                     /locus_tag="VVK04_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU3990575.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5756..5908
                     /gene="rpmG"
                     /locus_tag="VVK04_001963"
     CDS             5756..5908
                     /gene="rpmG"
                     /locus_tag="VVK04_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU3990576.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5918..6094
                     /gene="secE"
                     /locus_tag="VVK04_001964"
     CDS             5918..6094
                     /gene="secE"
                     /locus_tag="VVK04_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU3990577.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6149..>6680
                     /gene="nusG"
                     /locus_tag="VVK04_001965"
     CDS             6149..>6680
                     /gene="nusG"
                     /locus_tag="VVK04_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU3990578.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2076 a         1166 c         1443 g         1995 t
ORIGIN      
        1 tggtttcaga agtttctctt accaacatta accacaccat cggttattat tatggataat
       61 gcaagattcc atagaatggg taagttagaa cttttatgcg aggagtttgg gcataaactt
      121 ttacctcttc ctccctactc gcctgagtac aatcttattg agaaaacatg ggctcatatc
      181 aaaaagcacc tcaaaaaggt attaccaagt tgcaatacct tttatgaggc tcttttgtcc
      241 tgctcttgtt tcaattgact atagttcacg gatacagttg ggaaagaagc tattaaatat
      301 ttggagagtc cttttgggat gaacatgtca aatattacta tagatgggca agaaaagatg
      361 ggcaagaaat ggatttgagt caaacgatgc ttcttatgct caagtagtga gtctttatga
      421 tgatacaagt atctctgtta gtaataatga gacggacaaa gtgttggctg gatccctcta
      481 tactgataca aatgaacagg gattaacgat tccaagcagt ttactaaaaa attggaatga
      541 acagacagga aaaaatttga cagctaatga tcttattggc aaatcagtct cagtcagcat
      601 tgtagaaagt gctgccgaaa ctagtaagat tgctcaattt caaacgaaga ttgtacgtgt
      661 aatcaatgat gaagatgaca tggaggacag caacagtttc atgctgtctc atcaaatgga
      721 aacgattttg aaagaggctg gatttacgaa agctgtatct tattttatct tggaactcaa
      781 agatccatca cagacaaaag tagtaacaga agaattacag aaaaataaga agtatactgt
      841 gctttcttaa cagagagttc ttgatattgt gattaccttt attcgtgtta ttcagggatt
      901 attgattgtg ctttcatcac aagctattgt ggtagcagcg gttatgattg gtatcattat
      961 ttacatcaat atcatgcaac gttccaagga aataggtgtc atgaaagcag ttggttatca
     1021 gaatcgtgat gtcaaaggaa tttttattta cgaggctatc tggattgtag gcatcgcctt
     1081 gctgctggca tttttggttg cacaaggggt gggaagtttg gcgaatgcga ttgtaagtca
     1141 cttttaccca tccatcacta aggtttttga attaaatctt ttatctgttt taggaactct
     1201 agttttcgct ctattacttg gttatgtctc agcctacttc ccggcgcgta agattagtaa
     1261 aatggatcct gtagaatcgt tacgctatga atagtaaggg attccttgat ttacagtctt
     1321 aaaaagaaac taacatagaa aaacaatggc catacttgca attcaactca aatagttgta
     1381 taataggttt gttgaaaggt gatttgtagt gattcaagtt actcttttca caataaaaat
     1441 ttcatgattt tcataaggag gaaatcacta atggtagtta aagttggtat taacggtttc
     1501 ggacgtatcg gtcgtcttgc tttccgtcgt atccaaaacg tagaaggtgt tgaagttaca
     1561 cgcatcaacg accttacaga tccagttatg cttgcacact tgttgaaata cgacacaact
     1621 caaggtcgtt tcgacggtac tgttgaagtt aaagaaggtg gatttgaagt taacggtaaa
     1681 ttcatcaaag tttctgctga acgtgatcca gaacaaatcg actgggctac tgacggtgta
     1741 gaaatcgttc ttgaagctac tggtttcttt gctaagaaag aagcagctga aaaacacctt
     1801 aaaggtggag ctaaaaaagt tgttatcact gctcctggtg gaaacgacgt taaaacagtt
     1861 gtattcaaca ctaaccacga cgttcttgac ggtactgaaa cagttatctc aggtgcttca
     1921 tgtactacaa actgcttggc tccaatggct aaagctcttc aagacaactt tggtgttgtt
     1981 gaaggattga tgactactat ccacgcttac actggtgacc aaatgatcct tgacggacca
     2041 caccgtggtg gtgaccttcg ccgtgctcgc gctggtgctg caaacatcgt tcctaactca
     2101 actggtgctg caaaagctat cggtcttgta atcccagaat tgaatggtaa acttgatgga
     2161 tctgcacaac gcgttccaac tccaactgga tcagttactg aattggtagc agttcttgaa
     2221 aagaacgtta ctgttgatga agtgaacgca gctatgaaag cagcttcaaa cgaatcatac
     2281 ggttacacag aagatccaat cgtatcttca gatatcgtag gtatgtctta cggttcattg
     2341 tttgacgcaa ctcaaactaa agttcttgac gttgacggta aacaattggt taaagttgta
     2401 tcatggtacg acaacgaaat gtcatacact gcacaacttg ttcgtactct tgaatacttc
     2461 gcaaagattg ctaaataatt cttgagttga tagaaagcaa ggctttgtgg tcttgctttt
     2521 ttatatggaa aaatggatga cacgatcatc cattcttttt taattctttt tcaaatgtat
     2581 ttgaaagggt agtgaaagtt agcttctcta aagtaagtgg gtgggtaaag gaaagtcgga
     2641 aggcatgaag cataagccga cttgtctttg atttactatt atagagaggg tcgcccagga
     2701 taggaagatt atgatgcgaa aggtgcacac gaatctgatg ggttcgccct gtctttagct
     2761 tgcaacgagc caaggaagtc ttgtttgaga attgctttaa tctgcttaca tgcgtttcag
     2821 catattgccc attttttgca tcaactattc tttttctacg atcatggcga tcacgtccaa
     2881 ttttgtctct gaaaacaagt tcttttctgt tgatatttcc atcaactaga gcccaatatt
     2941 ctctagaaat ctcttttttc tccaataagc gattgagaat gggcaggata aaaggatttt
     3001 tggcaaagag aactaagcca ctggtttcca tgtccagacg atgaacgaca tagcaggttt
     3061 ggccaacata ggtactgaca tggttaagaa gggcaatttc gtttggttga ttaccatgcg
     3121 ttttcatccc ctctggtttg tttacaataa tcaagtgttg atcttgataa acttcctgca
     3181 ctaagtctgg gttgccccaa gggatcgtct tttggggata atcttcctcg tcaaaagtca
     3241 actggcaaac atctccagga tttacgattt ccttccagtg gacttcttct tgatttatca
     3301 aaatatgttt cttgattctc aaaaaatgac ggatttttct agggatgagg agttgttcct
     3361 caagtaattg ctttaccgtc atttgaggta gagaggcggg taatgtaaat gtgaattgca
     3421 tacagatatt gtaacaaaaa aagccctatt tggataggaa atagctaaat tcttgtcttc
     3481 ctatgatgaa gatgataaaa taaacgcatg aaattagata aattatttga gaaatttctt
     3541 tctcttttta aaaaagaaac aagtgaacta gaggactctg attctactat cttacgtcgc
     3601 tctcgtagtg atcgaaaaaa attagcccaa gtaggtccga ttcgaaaatt ctggcgtcgt
     3661 tatcatctaa caaagattat ccttatacta ggtttgagtg caggcttgct agttggaatc
     3721 tatttgtttg ctgtagccaa gtcgaccaat gtcaatgatt tgcaaaatgc cttgaaaact
     3781 cggactctta tttttgatcg tgaagaaaaa gaggctggtg ccttgtctgg tcaaaaggga
     3841 acctatgttg agctgactga tatcagtaaa aacttgcaga atgctgttat tgcgacagaa
     3901 gaccgttctt tctataaaaa tgacgggatt aactatggcc gtttcttctt ggctattgtc
     3961 actgctggac gttcaggtgg tggctctacc attacccaac agctggctaa aaacgcctat
     4021 ttatcacaag atcaaactgt tgagagaaaa gcgaaagaat ttttccttgc cttagaatta
     4081 agcaaaaaat atagtaagga gcaaattcta accatgtacc ttaacaacgc ttattttgga
     4141 aatggtgtgt ggggtgtaga agatgcgagt aagaaatact ttggagtttc tgcatcagaa
     4201 gtgagtctgg atcaagctgc gactctggca gggatgctca aggggccgga actgtataat
     4261 cccttgaatt ccgtagaaga ttctactaat cggcgcgata ctgtcttgca gaatatggtt
     4321 gcagcaggat atattgataa aaaccaagaa accgaagctg ctgaagttga tatgacttcg
     4381 caattgcacg ataagtatga aggaaaaatc tcagattacc gttacccctc ttattttgat
     4441 gcggtggtta atgaagctgt ttccaagtat aatctaacag aggaagagat tgtcaataat
     4501 ggctaccgca tttacacaga gctggaccaa aactaccaag caaatatgca gattgtttat
     4561 gaaaacacat cgctatttcc gagggcagag gatggaacgt ttgctcaatc aggaagtgta
     4621 gctctcgaac cgaaaacagg gggagttcgt ggagttgtcg gtcaagttgc tgacaatgat
     4681 aaaactggat tccggaattt caactatgca acccaatcaa agcgtagtcc tggttctaca
     4741 attaagcctt tagttgttta tacgccagca gttgaagcag gctgggcttt gaataagcag
     4801 ttggataacc ataccatgca gtatgacagc tataaggttg ataactatgc agggatcaaa
     4861 acgagtcgag aagttcctat gtatcaagcc ttggcagaat cgcttaatct acctgctgtt
     4921 gccactgtta atgatttggg tgtcgacaag gcttttgagg caggcgaaaa attcggactc
     4981 aacatggaaa aggtcgaccg tgttcttggt gtcgccttgg gaagcggtgt tgaaaccaac
     5041 cctcttcaaa tggctcaagc atacgctgcc tttgcaaatg aaggtttaat gcctgaagct
     5101 cattttatta gtagaattga aaatgctagt ggacaagtta ttgcgagtca taaaaattca
     5161 caaaaacggg tgattgataa gtctgtagct gacaagatga ccagtatgat gttggggact
     5221 ttcaccaacg gtaccggtat tagttcatcg cctgcagact atattatggc agggaaaact
     5281 ggaacaactg aagcagtttt taatccggag tacacaagtg accagtgggt aattggttat
     5341 actccggatg tagtgattag ccactggctt ggctttccga ccactgatga aaatcactat
     5401 ctagctggct ctacttcaaa cggtgcagct catgtcttta gaaacattgc caataccatt
     5461 ttaccctata cgccaggaag tacctttacg gttgaaaatg cttataagca aaatggaatt
     5521 gcaccagcca atacaaaaag acaagtacaa accaatgata atagccagac agatgataat
     5581 ttgtctgata ttcgagggcg tgcgcaaagt ctagtagatg aggctagccg ggctatctca
     5641 gatgcgaaga ttaaggaaaa ggctcaaaca atatgggatt cgatagtcaa tctatttcgc
     5701 taagatgctt gtcaaagcct agctttcttg ttataatgga taagatggag gcgttatggc
     5761 actaaaaaaa gcaagcctag cttgtgcggt ttgtggttcg agaaactatt caatcaagat
     5821 cagcggaaac cccaagccta cacgactaga agtaaataaa ttttgtaagc attgtggcaa
     5881 gtacactaca catagagaaa cgagatagga gagagcgatg cgttttattg gagatatttt
     5941 tagacttctt aaagacacaa cgtggccaac tcgcaaggaa agctggagag attttcgttc
     6001 tatcatggaa tacacagctt tctttgtagt aattatttac atttttgacc agttgattgt
     6061 ttcaggtttg attcgattta ttaacatttt ttagaagatt agtggagtta attacactag
     6121 aaatcttcta tttatgaaag gaaatatcat ggatagtttt gataaaggat ggtttgtttt
     6181 acaaacttat tctggttatg aaaataaggt gaaagaaaat ctattacaac gtgcacaaac
     6241 ctacaatatg ttggataata ttctacgcgt tgaaattcca acacaaacag tgcaagttga
     6301 aaaaaatgga aagagaaaag aagtagaaga aaatcgcttt ccaggttatg ttcttgtaga
     6361 aatggtcatg acagatgaag cttggtttgt tgttcgaaac acaccaaatg ttacaggatt
     6421 tgtcggatca cacgggaaca gatcaaaacc aactccatta ttggaacaag aaattcgtga
     6481 cattttggta tctatgggac aaactgttca agaatttgat ttcgatgttg agattggtca
     6541 aactgtacgt attattgatg gtgcttttgc agactacact ggtaagatta cagaaattga
     6601 taataacaaa gtgaaaatga ttatctctat gtttggtaat gacacagttg cagaagtaaa
     6661 cctaaaccaa atcgcagaat
//
LOCUS       DAVHBD010000069         6360 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000069 DAVHBD010000000
VERSION     DAVHBD010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.069"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(123..406)
                     /locus_tag="VVK04_001966"
                     /pseudo
     CDS             complement(123..406)
                     /locus_tag="VVK04_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(396..557)
                     /locus_tag="VVK04_001967"
     CDS             complement(396..557)
                     /locus_tag="VVK04_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU3990579.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            627..1391
                     /locus_tag="VVK04_001968"
     CDS             627..1391
                     /locus_tag="VVK04_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU3990580.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKAYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1647..1832
                     /locus_tag="VVK04_001969"
     CDS             1647..1832
                     /locus_tag="VVK04_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990581.1"
                     /translation="MLLTSSVLSATSKQCFELTSSVLSTTSKQCFEQPVTSFLSDALV
                     LIAYNQKEKFSPEKHIE"
     gene            2001..3380
                     /locus_tag="VVK04_001970"
     CDS             2001..3380
                     /locus_tag="VVK04_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU3990582.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3394..4059
                     /locus_tag="VVK04_001971"
     CDS             3394..4059
                     /locus_tag="VVK04_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU3990583.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4194..4268
                     /locus_tag="VVK04_001972"
                     /pseudo
     CDS             4194..4268
                     /locus_tag="VVK04_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4414..4953
                     /locus_tag="VVK04_001973"
     CDS             4414..4953
                     /locus_tag="VVK04_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU3990584.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            5020..5430
                     /locus_tag="VVK04_001974"
     CDS             5020..5430
                     /locus_tag="VVK04_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU3990585.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5546..>6360
                     /gene="pavB"
                     /locus_tag="VVK04_001975"
     CDS             5546..>6360
                     /gene="pavB"
                     /locus_tag="VVK04_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU3990586.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYG"
BASE COUNT         1712 a         1211 c         1470 g         1967 t
ORIGIN      
        1 atccacaacc ttaaaacagt gttttgagca gcctgcggct aacttcctag tttgcacttt
       61 gattttcatt gagtattact tcatcttttc ctgaaattga gtttttgccc aactcctctt
      121 gattattcta cttgaccggg ccaagcattt ataccacctt ctacgttggt aacggtgagg
      181 ccttgggagc tgagaaactg gcaggtagat gcagagcgga ctcctccgtg acaaatgaca
      241 tagtattcat ggtcaggttt gagttctttg tagccttgct ctaaggtatt tatggaagat
      301 ttttgggtcc tgcttggaat tcatgtgctt cacggacatc gataagttcc agattttcat
      361 tttgatattt tccataaaag tcagccatgc tgatactagt ttccatattc tactccttct
      421 gggttagcca ttttgtatag tgaataagcg ccgtcaaggt tttggacggt aaatcctgct
      481 tgcttgagga taggctctgc gatatagcta cgcaaaccac tgtggcagct gacgatgtag
      541 gcttgttttt tgtccagttc atcagcttcc tccttgacac tcggtcagat tttgatacaa
      601 tagtacaaaa ttagaggagg tgggctatga ttcagaaaca tgcgattccc attttagagt
      661 ttgatgataa tcctcaggcg gttatcatgc ccaatcacga ggggttggat ttgcagttgc
      721 caaagaagtg tgtctatgct tttttaggtg aggagattga ccgctatgcg agggaagtag
      781 gggcgaactg tgttggcgaa tttgtttctg ccaccaaggc ctatccagtt tatgtcgtga
      841 actacaagga cgaggagatt tgtctggttc aggctcctgt cggttcagct ccagcagccc
      901 agtttatgga ttggttgatt ggctatggtg tggagcagat tatctctact gggacctgtg
      961 gtgtcctagc tgatatagag gaaaatgcct ttctagtccc tgttcgcgct ctgcgagatg
     1021 aaggagccag ttaccactat gtggcacctt ctcgttatat ggaaatgcag ccagaggcta
     1081 ttgctgccat tgagcgagtt ttggatgata gagggattcc ttatgaagaa gtcatgacct
     1141 ggtccacaga tggtttttac cgagaaacgg ctgaaaaggt ggcttatcgc aaggaagaag
     1201 actgtgctgt tgtggagatg gagtgttccg ctcttgcggc agtagctcaa ttgcgtgggg
     1261 ttctctgggg tgaattgttg ttcacagcag attctctagc ggacttggac cagtacgaca
     1321 gtcgtgactg gggctcggaa gcttttaata aggcgctaga actgagttta gcaagtgttc
     1381 accaccttta gttgtactgg caaaggattt gttttatcat aaaatgtcta gctcatactt
     1441 ttcaaaaata tgtttaaacg aggtcacctt cctcttgtcc taggcatgtt gaggttggga
     1501 aaaatcttta aaatcagaaa aacgtatcat atcaggtgat gaaaactttg atactatgcg
     1561 ttttatgttg gtaagattta gagtgagatg aaatgatact cttcgaaaat cttttcaaac
     1621 caggtcagct tcaccttgcc gtagatatgt tactgacttc gtcagttcta tctgcaacct
     1681 caaaacagtg ttttgagctg acttcgtcag ttctatccac aacctcaaaa cagtgttttg
     1741 agcaacctgt gactagcttt ctaagcgatg ccttggttct cattgcctat aatcaaaaag
     1801 agaaattttc tcctgaaaag catatagagt agctggcgtt aaaagctcct gtcttgcttt
     1861 tttgacctat agtcacatct atcaagtatt gttcttgcct aagctatcaa taaaaaggtg
     1921 gcatttttta ggcttggtgt tagtgaattt tgccttatcc tatctaagtc atttcgagct
     1981 ttttatggta caatggaaac atgttattca aattatctaa ggaaaaaata gagctaggct
     2041 tatctcgttt atcgccagcc cgtcgtattt ttttgagttt tgccttggtc attttactag
     2101 gctctcttct tttgagcttg ccctttgtcc aagttgaaag ctcacgagcg acttattttg
     2161 atcatctttt cactgctgtc tctgcagtct gtgtgacagg tctctcaacc cttccagtag
     2221 ctcacaccta taatatctgg ggccaaataa tctgtttgct cttgattcag atcggtggtc
     2281 tagggctcat gacttttatt ggggttttct atatccagag caagcaaaag cttagtcttc
     2341 gtagccgtgc aactattcag gatagtttta gttatggaga aactcgatct ttgagaaagt
     2401 ttgtctattc tatttttctc acgacctttt tggttgagag cttgggagct attttgctta
     2461 gttttcgcct tattcctcaa cttggctggg gacgtggtct ttttagttcc atttttctag
     2521 cgatctcagc cttctgtaat gccggttttg ataatttagg gagcaccagt ttatttgctt
     2581 ttcagaccga tttactggtc aatctggtga ttgcaggctt gattattaca ggcggccttg
     2641 gttttatggt ctggtttgat ttggctggtc atgtaggaag aaagaaaaaa ggacgtctgc
     2701 actttcatac gaagcttgta ttattattga ctataggttt gttgttattt ggaacggcaa
     2761 ctactctctt tcttgagtgg aacaatgctg gaacgattgg caatctccct gttgccgata
     2821 aggttttagt tagctttttt caaacagtga cgatgcgaac agctggcttt tctacgatag
     2881 attatactca ggctcatcct gtgactcttt tgatttatat cttacagatg tttctaggtg
     2941 gggcacctgg aggaacagct gggggactca agattacgac attttttgtc ctcttggtct
     3001 ttgcacgaag tgagcttcta ggcttgcctc atgccaatgt tgcgagacga acgattgcgc
     3061 cgcgaacggt tcaaaaatcc tttagtgtct ttattatctt tttgatgagc ttcttgatag
     3121 gattgattct gctagggata acagccaaag gcaatcctcc ctttatccac ctcatatttg
     3181 aaactatttc agctcttagt acagttggtg taacggcaaa tctgactcct gaccttggga
     3241 aattggctct cagtgttatc atgccactta tgtttatggg acgaattggt cccttgacct
     3301 tgtttgttag cttggcagat taccatccag aaaagaaaga tatgattcac tatatgaaag
     3361 cagatattag tattggttaa gaaaggaaag agcatgtcag atcgtacgat tggaattttg
     3421 ggcttgggaa tttttgggag cagtgtccta gctgccctag ccaagcagga tatgaatatt
     3481 atcgctattg atgaccacgc agagcgcatc aatcagtttg agccagtttt ggcgcgtgga
     3541 gtgattggtg acatcacaga tgaagaatta ttgagatcag cagggattga tacctgcgat
     3601 accgttgtag tcgcgacagg tgaaaatctg gagtcgagtg tgcttgcggt tatgcactgt
     3661 aagagtttgg gggtaccgac tgttattgct aaggtcaaaa gtcagaccgc taagaaagtg
     3721 ctagaaaaga ttggagctga ctcggttatc tcgccagagt atgaaatggg gcagtctcta
     3781 gcacagacca ttcttttcca taatagtgtt gatgtctttc agttggataa aaatgtgtct
     3841 atcgtggaga tgaaaattcc tcagtcttgg gcaggtcaaa gtctgagtaa attagacctc
     3901 cgtggcaaat acaatctgaa tattttgggt ttccgagagc aggaaaattc cccattggat
     3961 gttgaatttg gaccagatga cctcttgaaa gcagatacct atattttggc agtcatcaac
     4021 aaccagtatt tggataccct agtagcattg aattcgtaaa gagggatgac ccctcttttt
     4081 tgatgcccaa gatggcaaat agagacagaa gccccttgtc ttctagtaaa agttcttcaa
     4141 aggctggact ttatggtaaa atagaaggaa gtgacaagag agagtaatac tcaatgaaaa
     4201 tcaaagatca aactaggaaa ctagctgcgg gctgctcaaa acactgtttt gaggttgcag
     4261 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgcagataga actgacgaag
     4321 tcagtaacat ctatacggca aggcgacgtt gacgcggttt gaagagattt tcgaagagta
     4381 taagaaaaaa tcaatcccct aaaggagcag attatgaagt tattgtctat cgccatttct
     4441 agctataatg cagcagccta tcttcattac tgtgtggagt cgctagtgat tggtggtgag
     4501 caagttggga ttttgattat caatgacggg tctcaggatc agactcagga aatcgctgag
     4561 tgtttagcta gcaagtatcc taatatcgtt agagccatct atcaggaaaa taaaggccat
     4621 ggcggtgcgg ttaatcgtgg cttggcagag gcttctgggc gctattttaa agtagttgac
     4681 agtgatgact gggtggatcc tcgtgcctac ttgaaaattc ttgaaacctt gcaggaattt
     4741 gagagcaagg gtcaagaggt ggatgtcttt gtgaccaatt ttgtctatga aaaggaaggt
     4801 cagtcttgta agaagagtat gagttacgat tcagtcttgc ctgttcggca gatttttggc
     4861 tgggaccagg tcggaaattt ctccaaaggc cagtatatca tgatgcactc gctgatttat
     4921 cggacagatt tgttgcgtgc tagccagttc taattgcctg aacatacttt ttatgtcgat
     4981 aatctctttg tctttacgcc ccttcagcag gtcaagacca tgtactatct gcctgtcgat
     5041 ttctatcgtt atttgattgg gcgtgaggac cagtctgtca atgagcaagt gatgattaag
     5101 tgcattgacc agcaactcaa ggtcaatcga ctcttggtag accaacttga tttgtcccaa
     5161 gtgagtcatc ccaaaatgcg agaatatctg ctgaatcata ttgaaatcac gacggtgatt
     5221 tccagtaccc tgctcaaccg atctggaaca gcggagcatc tggcaaaaaa acgccaattg
     5281 tggacctata ttcagcagaa aaatccagaa gtctttcagg ctattcgtaa gaccatgttg
     5341 agccgtttga ccaaacattc tgtcttgcca gatcgcaaac tgtccaatgt cgtctatcaa
     5401 atcaccaaat ctgtttatgg atttaattaa tataagtgtt ttataagagg gatttaagaa
     5461 aaattttaac tttttcttag tcctttttaa tttcaggaga ttatactaga gtcatcaaat
     5521 aaagaaagac tctaaggaga atcctatgaa attcaatcca aatcaaagat atactcgttg
     5581 gtctattcgc cgtctcagtg tcggtgttgc ctcagttgtt gtggctagtg gcttctttgt
     5641 cctagttggt cagccaagtt ctgtacgtgc cgatgtggtc aatccgaccc caggtcaagt
     5701 cttacctgaa gagacatcgg gaacgaaaga gggtgactta tcagaaaaac caggagacac
     5761 cgttctcact caagcgaaac ctgagggcgt tactggaaat acgaattcac ttccgacacc
     5821 tacagaaaga actgaagtga gcgaggaaac aaactcttct agtctggata cactttttga
     5881 aaaagatgaa gaagctcaaa aaaatccaga gctaacagat gtcttaaaag aaactgtaga
     5941 tacagctgat gtggatggga cacaagcaag tccagcagaa actactcctg aacaagtaaa
     6001 aggtggagtg aaagaaaata caaaagacag catcgatgtt cctgctgctt atcttgaaaa
     6061 agctgaaggg aaaggtcctt tcactgccgg tgtaaaccaa gtaattcctt atgaactatt
     6121 cgctggtgat ggtatgttaa ctcgtctatt actaaaagct tcggataatg ctccttggtc
     6181 tgacaatggt actgctaaaa atcctgcttt acctcctctt gaaggattaa caaaagggaa
     6241 atacttctat gaagtagact taaatggcaa tactgttggt aaacaaggtc aagctttaat
     6301 tgatcaactt cgcgctaatg gtactcaaac ttataaagct actgttaaag tttacggaaa
//
LOCUS       DAVHBD010000070         5894 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000070 DAVHBD010000000
VERSION     DAVHBD010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.070"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(173..1183)
                     /gene="ccpA"
                     /locus_tag="VVK04_001976"
     CDS             complement(173..1183)
                     /gene="ccpA"
                     /locus_tag="VVK04_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU3990587.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1608..2207)
                     /locus_tag="VVK04_001977"
     CDS             complement(1608..2207)
                     /locus_tag="VVK04_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU3990588.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLMLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERNIADLMQTLHTVLEGRKEYSPELMEVVMMHPNPLTEQEIAVLKGIAQGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2208..3305)
                     /locus_tag="VVK04_001978"
     CDS             complement(2208..3305)
                     /locus_tag="VVK04_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU3990589.1"
                     /translation="MLERLKRIHYMFWISLIFMIFPILSVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKSSLTQEL
                     ESTASMILLELVTNIIKHAKASKVYLKLERTEKELILTVRDDGCGFASISGDELHTVR
                     NRVFPFSGEVSVISQKHPTEVQVRLLYKERK"
     gene            complement(3305..4042)
                     /locus_tag="VVK04_001979"
     CDS             complement(3305..4042)
                     /locus_tag="VVK04_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU3990590.1"
                     /translation="MKRWLALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTGFSMMSTAIFSFPAVLHTDKMNNWQKILRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLILGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPVSLFPDWMQAIGKRLPSYQLMELIKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(4044..4928)
                     /locus_tag="VVK04_001980"
     CDS             complement(4044..4928)
                     /locus_tag="VVK04_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU3990591.1"
                     /translation="MNMIKVESLNKNIKGKAILKGISFEVAEGECVALIGPNGTGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELIAFFQRIY
                     PNSLSDQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLVQAGCGIQEIEV
                     NNRSLLDTIFEETQKGDN"
     gene            complement(4915..5109)
                     /locus_tag="VVK04_001981"
     CDS             complement(4915..5109)
                     /locus_tag="VVK04_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990592.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(5106..5237)
                     /locus_tag="VVK04_001982"
     CDS             complement(5106..5237)
                     /locus_tag="VVK04_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine aminotransferase"
                     /protein_id="HEU3990593.1"
                     /translation="MFSGLDESFYHFPWELFAGFGMMSWLVREGLKLVGDVKKELEE"
BASE COUNT         1871 a         1321 c          961 g         1741 t
ORIGIN      
        1 caacctcaaa gcagtgcttt gagctgactt cgtcagttct atctacaacc tcaaaacagt
       61 gtgttgcgca gcctttaacc agccgcctag tccgctctat ggtattcatt aagtcaacat
      121 ctcttgttta agagcacaaa atcaggaaat cttctcgatt ccctgatttt ttctatttac
      181 gttttcgtgt tgagctacgt tctgtcaaac catgaggtaa gagaacttca cgttcttcca
      241 actcttcctt atgcataatc ttggtcaaca tacgcatact aatggcacca aggtcataaa
      301 gaggttgggc aatcgttgtc aagtttggac gggtaaagcg tgagatttgt gaatcatcac
      361 tagtaataat ttcaaaatct tctggcacag aaacaccctt atcagccaaa ccgttcaaga
      421 ctcctgctgc caactcatca cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac
      481 gctctgctaa ggcgtaacca tcatcatagc tatatttaga ttcaaatacc aaaccctcac
      541 tataagtgat tcctgctttt ttcaaggttt ccttgtagcc aactaaacga accttaccat
      601 tgatgtcatc cactagcgga ccgctaacga aagcaatacg ctcattttct ttagcaaggt
      661 aactcactgc atcaattgtt gcttgcttat agtcaatatt gacacttggc aactggtgct
      721 caacatcgac agttcctgcg agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa
      781 ttttatctgt caagtgatac cccatataga taatgccatc tacctgcttt gaaaagaggg
      841 tattgacaac agaaacttct ttctcgttat cttcatcgct attagctagg acaatattgt
      901 acttgtacat ttctgcaata tcatcaatcc ccttagccaa actcgaaaaa taaccattgg
      961 taatatttgg aatcacgaca ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa
     1021 ctgcatttgg acgataatcc aaacgatcaa ttacctctag cactttttta cgggtattct
     1081 cttttacatt tttattgcca ttgaccacac ggctgaccgt cgccatggaa acacctgctt
     1141 cacgagcgac atcataaatg gttactgtat catctgcatt cattcctttt cctgtccttt
     1201 ctatctcaca cattctttta caagtagagg tactgattga agctctatat ctacttacaa
     1261 aagtgaagat gtgaaaattt cgttttcata tttctactta ttccattcta tcactaattg
     1321 taaacacttt caagtgtttt ttgaagattg attgaaaaaa tttcatagaa aacctaggtt
     1381 tagctccttg ctaccacctt agactaaaca aaaaggagga aactaagccc tcctaaagtt
     1441 atagtaaaat gaaataagaa caggataaat cgatcaggac agtcaaatcg atttctaaca
     1501 atgttttaga agtagaggtg tactattcta gtttcaatct actataggta ttgttccatt
     1561 cactaccgtc aattttagca catagtcttc atgaaaatat tatatcatca taaccaacca
     1621 gattctttcg cgatattagc tgcctctgtt cgattacctg catctagttt cgaaagaata
     1681 ttggtgacat agtttcggac tgttccgttg gatagataaa gtttgtctgc aatttcttgg
     1741 ttagagaagc cctgagcaat tccctttaaa actgcgattt cttgctccgt taatggattg
     1801 ggatgcatca tcaccacttc catcaattca ggcgaatact ccttgcgtcc ttcgaggacg
     1861 gtgtgcaagg tttgcatgag gtctgcaatg tttctttctt ttaatacata agcatctact
     1921 ccagccttga ccgcacgttc aaaataccca ggacgcttga aggtcgtcac cacaaccacc
     1981 tttgtttcaa gcttttctgc tcgtatccac tccaagactt caagacctgt cttaacaggc
     2041 atttctacgt caaggatggc gatatctaca gactcctttt ctaatagttg gattgcttct
     2101 tgcccattct tggcttgaaa gacagactct acatccggtt gaagcatgag caactggcac
     2161 atggcatctc gcaacatact ttgatcttct gcgactaata ctttcatcta ctttctctcc
     2221 ttataaagta gtcgaacctg cacttcagtt ggatgtttct gactgattac acttacttct
     2281 cctgaaaatg gaaaaacacg atttcggact gtatggagct catccccgct tatagaggca
     2341 aagccacagc catcatctct cactgttaga atgagttctt tctctgtccg ttctaatttc
     2401 aagtagactt tagacgcttt agcatgtttg atgatattgg tcactaattc aagcaaaatc
     2461 atggaagccg ttgactccaa ttcctgagtt aagctagact tgtccaagtg attctcaact
     2521 tgaacctcaa ttccagcaat ttctaacatc tttttcacag tctctagttc ggatgtcaaa
     2581 gttctagact taagattttc cacaatggtt cgcacttcat tcatggaatc cttgctgatc
     2641 tggtgaattt cttttaattc cttttccacc tgtggataag cctccatctg aaataactgc
     2701 aaggctaaat ctgtcttgac actcagcata gcaaaggtat gtcccagact atcatgcaaa
     2761 tcctgaccga tacgactacg ttcattttca gcaagcaata gatttatctg ggcattttgc
     2821 ttgacctgag cttctttcaa atcctcgaca atacgaatcc gaaccaatcc aaaagtcatt
     2881 aaatcgacaa aagtaagaat tacaagtaga tagaatagaa actcaacttc gattctctga
     2941 aaaatcaaca gttgccccac aacaaggact tgagcaagaa gaaaagtcca gacatgtaaa
     3001 gactttaaac tacgtacgct gaaatgataa cttaagagat tggataggaa aaagaaaaac
     3061 cagatataat taacagcaac aaaggcagta ttcccaacta cataagtcag catgaggccc
     3121 caatatagcc aagataggcg ctggctctta gttgttaaaa cacccaaata tgccactaca
     3181 aatagaatat caatcaataa atgccaggca gaaagccacc cagtcactac agacaggatg
     3241 gggaaaatca taaaaattaa actgatccaa aacatataat gtattctttt cagtctttca
     3301 agcattaagc attctcctta tgaccttgaa ggtaaatagt caaaccaaat aaaactgctg
     3361 aaaaaacaag tagataaact gtggctgata gattgattcc accctcattt aagaaggtct
     3421 tgattaattc catcaactga taacttggta aacgcttccc gattgcttgc atccagtctg
     3481 gaaataaaga gacgggcatc cagagtccgc ctaaaacagc caatcctaga taaagaagat
     3541 tgcccacgac agacatcagc tgactagttg gtaatagcgt caaggttaag ccaagtgcta
     3601 caaaagcaat acttcccaaa atcagcaaaa tcgcagctcc aacccatttt actagaggca
     3661 tgtctacacc tcttacaaaa tgtccaactg taaaaacaac cagaattgag accaaataat
     3721 caaccagcat acttgttatc tttgatagat aatattctac catatttact gggctatgac
     3781 gtaatatttt ctgccagttg ttcatcttgt cggtatgtaa gacagctggg aatgaaaaga
     3841 tagcggtcga catcatggaa aagccagtca tggagatgag gtaatcacgc ataaaattcg
     3901 cgggtccacc tggtgtgtcc tggtacatgc cagaaaagaa tagatagaag gctgtcggca
     3961 tccctactga caatagataa tagatcaatt gtcgtttggt caataaaaat tctatcttac
     4021 taagtgctag ccatcgcttc atcttagtta tctcccttct gcgtttcttc aaagattgta
     4081 tccaacaaac tacgattatt aacttcaatt tcttgtatgc cacatcctgc ttgaactaac
     4141 agttcccaaa aagcatctgc ttcgcgtgtg actacttgta gagcatcctg tttttgtgac
     4201 cagttttcaa ccaagttaga ctgctcaatg acttccttgt atgccagagg aaggataaaa
     4261 tgcttttcaa ttccctcact acgcatagct agaggcgtcg tatcacgaat caactctccc
     4321 ttatttaaaa ccaaaatccg gtcagccgta tgctctacct cttcaatata atgagacgaa
     4381 tagagaatcg tgactccttg cgcttttagg tcccgaacga tttcccaaaa gcgttgacga
     4441 gttgaagtat ccatggcagc agttggttca tctaaaaaga caagctttgg tcgcccaatc
     4501 aaggtcaaga caaaagagaa gagacgcttt tgcccgcctg acaatttttc tgcgaattgc
     4561 tctttttgtt gctggtcaaa ctgcaatagt tgatcgattt cctgatcgct caaggaattt
     4621 ggatagatac gttgaaagaa agcaatcaac tctttgacct ttaatttctg aacgatgaca
     4681 ttttcttgag gcagataacc tctaatatag tctaactgag aactcgtcac tgacaagcct
     4741 tggatggata cttgaccgct tgtgaccagt ttatctccaa gcagacagtc caagagtgtg
     4801 gtcttcccag taccattggg cccaatcaag gcgacgcatt caccttcagc tacctcaaag
     4861 gaaataccct tcaaaatagc cttgcccttg atgtttttat ttaggctttc taccttaatc
     4921 atattcatga tattctcctt tcaaccactc cattctcata aggaaaacga cgaaaatcat
     4981 aaatccaaac cccaaagcac cacgaatgaa ttggcgaagc aaggtttggt caaaccaacc
     5041 tgtaaacatt tccactaacc ataccaagag tgacaggccg ataaagaaat agatgatccc
     5101 tctcttcatt cctcaagctc ctttttcaca tctccgacta atttcaaacc ttctctaaca
     5161 agccaagaca tcattccaaa gccagcaaag agctcccaag gaaaatgata gaaactctca
     5221 tccaatcccg aaaacatgag ttaggtcata actcctgcta ctactaaact cactgcgata
     5281 atcattttat ttctcatctc ttcttcctcc atttcatact acaattatag tcttttgaaa
     5341 tcagaggaga cagaagcttc tgtcactaga aaatatgaca aatgtcataa aaaattctgt
     5401 tcaaaacaag caagatacac tatacaataa aacacaatta gaaaaatcta aggcaacttc
     5461 ctcaaaagag atatcaaacc caattcacac cataatgtaa actaatactt atttaaaatc
     5521 aaaaagagta gaaattttta tcagacaaac acatatatag tgtattgaat ctataacagt
     5581 aggccttaaa tactaaaata tttctataaa ttaatttaac tttcctgata gagctgttca
     5641 tatcttattt caattctcta aattatacgt tgaacaaaac ccttctattt ctttcttaaa
     5701 gatttataag agttataaaa tctgttaaat ttcaatgtgt atacctaaac tacggtattt
     5761 attgaaaaga ctggagacaa aaagtatacg ctgccaaaat gaattactga aaatcaaaaa
     5821 agagagaacc aaactgattc cctcttaatg tatataatat ctagttttaa aaatacacac
     5881 tcacatatct ctgt
//
LOCUS       DAVHBD010000071         5688 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000071 DAVHBD010000000
VERSION     DAVHBD010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.071"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(108..599)
                     /locus_tag="VVK04_001983"
     CDS             complement(108..599)
                     /locus_tag="VVK04_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990594.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            complement(580..1176)
                     /locus_tag="VVK04_001984"
     CDS             complement(580..1176)
                     /locus_tag="VVK04_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3990595.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(1173..1655)
                     /locus_tag="VVK04_001985"
     CDS             complement(1173..1655)
                     /locus_tag="VVK04_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEU3990596.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(2799..3095)
                     /locus_tag="VVK04_001986"
     CDS             complement(2799..3095)
                     /locus_tag="VVK04_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEU3990597.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(3626..4519)
                     /locus_tag="VVK04_001987"
     CDS             complement(3626..4519)
                     /locus_tag="VVK04_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3990598.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLRLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(5273..5503)
                     /gene="blpU"
                     /locus_tag="VVK04_001988"
     CDS             complement(5273..5503)
                     /gene="blpU"
                     /locus_tag="VVK04_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU3990599.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
BASE COUNT         2119 a         1004 c          637 g         1928 t
ORIGIN      
        1 ttcaacccac tacagttgac aaagagccga aaatataaga attacaagtt aacaaaaccg
       61 aaatgatttc atatcattat taagtaaaga aaaaaatttt agtatttcta aaaactattt
      121 ataatagaca ttatagcatt aaataaaaat ggtacagaaa acactactgt caatcttaaa
      181 tttttaaatc tcgcataatt tgttatccca attagtaata ctgtcaatac gctgaaatag
      241 gcaaacttta tatccgatgg attaaataaa taacaaagta aaatgctaaa acttaaggtt
      301 atatttttag ataaaagaat atctccaaag ttcctcttat tcttatcaaa aaataatgta
      361 atcagaaaga gagaaaatcc atattcaata agagttgcta taaatgtgaa aacaacagaa
      421 atcactgtca atattgtttc tattttaatt gtaaaaagat tagatagttc agataattta
      481 tcaatttgtt catctaaaat tcccgacttc atcagtaaat caataaacaa atataaaaga
      541 aaaagataaa taatcagatt cattaatttg tataaactat tatttgtttg aaatttcata
      601 aacccgtcct tcctctatta aaatcctttg agatttgcta atcaattctt gattcaataa
      661 attatgagat acatatataa tagtagagct ttctttcatg gaaattaagc gtttagcaat
      721 catatcaata cttcttgcat ccactgttga taaagtctca tcaataaaaa tataatccca
      781 atttttagca aaaattaagg ataagcctaa tttgaatttt gttccagtag atgctgtcat
      841 atagttatct ccgattttat tatcaaaaaa agtattaatt tgttctttat cctcaaatga
      901 tagatggatt tgaaaagaat cacacaacaa ctgcaaattt tcttctatag taaatggaac
      961 aaccccaagc tgattggtat caaggtatag tacatctttg gagacacaat tctttaaacc
     1021 actatcaaaa gtctctagcc cagctaaaag ttgtagaagg gtgctctttc ctgaaccatt
     1081 ctctccttca actctgtaaa ttcccttatc aatctctagt gatatatttt tcaatataca
     1141 tttatcataa cttttagatt cattttcaat tttcataatt taattccctc tatcaacgct
     1201 gctaaaatta ataaaagata agaaatgata taccatttta aattactttt tatataaata
     1261 agtatatttt taattcccct atccttcaat aatcggtata aaagatactg actcatacct
     1321 tgataccaaa taaaattcgg tatttcaata agagcatgag gtaatattcc ttttattgta
     1381 gctactattc caatcatctg accagatata cccaattgta ttcctaaaga tagcaaatca
     1441 aaaagttgca ataagggcga aatcggaaaa cagaatagat atagcaaaaa atttgtagaa
     1501 tttgcctgta aaactgtcaa tgtaaattgt aattccagtt tcggaggtat agtagcaaaa
     1561 gtctcatttt ttaatataaa gcttaaaagt aaacctagta aaaaacagac tatacaaaat
     1621 aacacatagt aaatcagaaa accacttttt ctcatctaat gccccctact aaaattacaa
     1681 atattatcag aaaacaatat aaaaccagaa aactccatct caataaacta actgtacctt
     1741 taattaaaaa tagagctttc ttataataga cataggctat aaaataattg aatggaatca
     1801 ataacaaatt caacaaaata ctttttatat cattactata acttgtcacc ggaatcaaac
     1861 ataacaacaa tgaaaattgt aagaaagaga ttaaatgcgt caacatcatt agttgtgcat
     1921 tcttaaaaaa gaaattcatt ttagaatgat taagagcaga taattgaagt aaagctagat
     1981 ctaccccaat tgaggattta tgattcccta ttattgcctc cattaatgta atatatattg
     2041 aggtataaag aaataatatt ggtatttttg tgtcatcaat tgataacatc gtcatcatat
     2101 accaaaatag ataggaaaga agaatactaa tcaaaataaa agaaaaagtt aaccctttat
     2161 ttaaccaaca aaaacgaagc aatataaata gactgctacg aaatcttttt tgactcattc
     2221 gactgctttt aaaatagaaa ttactcgcat gattatctaa tatccccatg actaaaataa
     2281 aataattgag tagtatgaca taaattacaa cttgtccttg ttctatagac aatagtccta
     2341 tagataaaaa taagaacaat ttacttataa ttgaaaacaa actaggtaga attaaagaaa
     2401 taatttgaat agctatcaaa caaagagtaa tggataaata aaaatatcca ataatatcta
     2461 gaaaatacaa aataaataaa taaataaatg aatgattgta aaatttggaa agaataatat
     2521 ttcttgacaa tggcaagaag atagagaaaa atatagtttt tccttatata gaaagtattt
     2581 atttttttac tttggataga cagtttcata ttataacgat tcaaagtagc gtaatctact
     2641 accaaaaaaa gtaaaaataa tttcccttga aaaggaagat agcttttaaa atagattgac
     2701 aaacttatga taacaaaaaa caaaagggtt atcccaataa aattaagata acctaaaata
     2761 ctttcacatt cttttttaga aagtattttc atctagttct accatagagc tgctttagca
     2821 gcacctttct ttttcaatat ataaagaact gttgctgcaa tacccgaacc aatagaacct
     2881 actcctgtga ttgcacctac aattgaaatt actgctgtaa ctgtactata agcactaatc
     2941 aaattgacta cagtagcagc agcttttgtc gaaattccta atgtcccagc caacatagga
     3001 aaagaaacaa cacctaagct taaccaacta atgactgcta acattgctga aacaataaga
     3061 aatttattat gaaattccat tcttttagat ttcattttag tgtactcctt ttgtatatta
     3121 tgtatgtttt attgagagtt aattcgcaca tgttgtattc ctaactctct tcaaatgttc
     3181 gtctatattt tatactactt ttattaacat atctataata aataaattac tactacattt
     3241 tcctagatta tcaaattact tttatatcac taagactcaa taaaagataa tgtctattta
     3301 acttttatac gattactact tcctttttag tttacacttc ctacatcata aataaacata
     3361 ctcaaccctc acaatctcca aataactctt ctatatcatt gaaaattgag tttcatcctc
     3421 tatactaatg taggacattc ctttaatcca atataagaat accttgttcc attaatctct
     3481 acccgatatt atagatagaa ccaaattcct atacttaaaa ggacaaataa cgttccaccc
     3541 ataataaacc tcctttcttt ttgagaacgt cttctttata ggtttagtat agcaaaaaca
     3601 tgaaaaaaac aacatgactt agaagtcagg ttgttgggaa atctatctgt ttttctgcta
     3661 aaattctctg aactaatacc tgatcgtcta gcaattctgc tagagaaatc gccttttcat
     3721 agaaactttc tgcctctaaa atattcttgt ctacaaataa agcatatttt gcctttagca
     3781 aaaatagatg aggtcggtaa aaaacatgtc ttgttttagc aataattttc tcaaatgttt
     3841 gaatatatat cagactatct tctgtctgaa tttggataaa taggctcaga agaacttttt
     3901 ccatttgaac taggctagcc ttatcttcat attctgaaca tagcaatact ttttgagcta
     3961 actcctcaaa atgttcttta tcttctaatc ccatagcaca acaaaagaaa tacaattcaa
     4021 taatcaacaa atcatttaca gaaaaatatt tcttttttaa taactgctgg aaatattctt
     4081 ccactaacct taaaccgtag gtcacatctg aactaccata aatatcaaaa cgagcttgtg
     4141 tcacatccac aattaactgc tcttcctcag gcaaattctc ataatagttt tcatatattt
     4201 cctcaagtat agcttctttt cgttcgattc ttcccttatc agcgtaggtt tgagaatgaa
     4261 tcagctcatc tttgagtttt aggaatcctt ttggaatctc tataacctta acatccacaa
     4321 tattctgtaa tgatactcca agtttatccg caatcaataa taatttagga agtgttgcta
     4381 aagcttgccc attttcaata cgtgctagct gacgaatcgt caactctgat tcatcaccac
     4441 aaatatctat ctgagttttt ccacaagatc gcctaatagt tttgatttta taaccaattt
     4501 cacgtttcaa ctcatccata gtaatactcc ttaagttgat tacaaagatt tctttttctt
     4561 cctaattctt ttgtcaatca tatataaaac gataagcgaa aacagcggta gaacaatata
     4621 actcttttca ctcattatca gctgaaatcc cagggttgct agtatcttaa agatgaaaat
     4681 attcatcaaa aatagaaaaa caaatactaa aaaatatttt aaaaccttct tcatttcttt
     4741 tcttcaactt tcctaatttc tacacctatt ttatcgaaaa tatatataaa actccaaata
     4801 aacacttcga ctgcactttt tttggcaaaa aatagacaga acaaacatcc tacctactaa
     4861 aaatatgata tgaaaggaaa atgatttttt actgacaccc taggcaagct tgggacaaat
     4921 aaatcattga tagcaacatt tacgacatcc tatttaaagt tccttcaatt tctaatgtcc
     4981 ccgctatttc taagccacct ctggtatgat ctattcctag tcagaataga taacaccgtt
     5041 ctaaattacg attcatagtt actccttttt tgactcgtta ctataagact cctctttaca
     5101 tgcgcaaaat aattttgatt cagattcatc atttatagtt ttgattattt tttaacagat
     5161 ttttctgttt tcttctccga agactttaaa aatttttttc taattaaatc atccatataa
     5221 ggaccaaata taccaactac taaaccaata ataaaacttt taaaatccat aattaccacc
     5281 aacatgtcgc tgcataggcc acacctccaa gtatagctcc tcccacagca ccagttgctg
     5341 caccttgcca tgttcttgtt ttaattccta gctgaagacc tcgtgctgct cctcctccaa
     5401 cacctgcttt ggcaaaatct ccccaattgc atccgccacc ttcaacgcaa gcaagcatct
     5461 cagtatccat aatttcaaat tgtgacatcg tttttgtatt cataacgaat acctcttttt
     5521 tatttttaat atttgtcttg ttacaaactt gacaagttta gtataacagt atctattaat
     5581 ttttttcatc caaatcttga attggcatcg aaacgtcttg aattagcttt tttgtttcaa
     5641 aatcatctct atttttaaaa aagatgtttt ctaatcactt ttttacta
//
LOCUS       DAVHBD010000072         5682 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000072 DAVHBD010000000
VERSION     DAVHBD010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5682
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.072"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            1262..2521
                     /locus_tag="VVK04_001989"
     CDS             1262..2521
                     /locus_tag="VVK04_001989"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU3990600.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2537..3088
                     /locus_tag="VVK04_001990"
     CDS             2537..3088
                     /locus_tag="VVK04_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU3990601.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            3081..4358
                     /locus_tag="VVK04_001991"
     CDS             3081..4358
                     /locus_tag="VVK04_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU3990602.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4374..5234
                     /locus_tag="VVK04_001992"
     CDS             4374..5234
                     /locus_tag="VVK04_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU3990603.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5459..>5682
                     /locus_tag="VVK04_001993"
     CDS             5459..>5682
                     /locus_tag="VVK04_001993"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990604.1"
                     /translation="MSQSIVPVEIPQYCRFDSKKRNGILFNVRIANLKFTFFRLDFLR
                     NKIWYSSSMNDEASKQLTDARFKRLVGVQRT"
BASE COUNT         1732 a          922 c         1283 g         1745 t
ORIGIN      
        1 tttctaatga tggttttgtc gcttttcatt ataggtcata tgggactttt tttctacaca
       61 aaaataggct ccataatatc tatagtggat ttacccacta caaatattat agagccaaaa
      121 atcccgtgcc acatcaaaca cgggattttg tggtacgacg ggcatgtata gcgaactgaa
      181 tctggaatag cacagcatat cttctaaaat atagtaaaat gaaatgagaa cagaacaaat
      241 cgatcaggac agtaaaatcg atttctaaca atgttttaga agcagaggtg tactagtcta
      301 gtttcaatca actatattgt tataaattga tttgaatttc aaaattaaat tgtttgattc
      361 ttatttcaat ttgttatagt atatctgatg tcaaagttct cggcgagtca aatagcgatt
      421 cccaagcctg actatcgtga ggtagtggat taaaacggtc tggggataga ccgttttaag
      481 tctgacgctg gaaataagaa tcgtcagagg aagggatagc gaaatcgtgg ctttacgaac
      541 aggaacgtga tagtaaggcg tatatagcgg ataagggggt ctcaaactct aaagtccaaa
      601 aaggtagtcg taacctatat gcgtaaatca cgagagtaat tgaattcgta ctaagatttt
      661 ctattttcac tgtaaccttt taacgtcctt atatcttgta tacacgagga aagatgtacg
      721 acttatcccg tgaggtctat cactataaag agaaaacgac agatagaagt gatcctgagt
      781 cacggttatc tttaaaatag attgtctgat aggacggtat gtataaaacg cttctgtgaa
      841 ctgagagaag gggagaagtt cttgctaaaa tttagttgaa cagccgtatt ccgatactta
      901 gataagagat ctagtcttag atcctactca gttttagggg ataaaaaagg ggcaatagcg
      961 attcgagaaa gattatactc ttcgaaaatc tcttcaaatc acgtcaatat cgccttgccg
     1021 tatatgtagg atactgacta cgtcagttcc atctacaacc tcaaaacagt gttttgagca
     1081 acctgcggct agtttcctag tttgatcttt gattttcatt gagtattagt aattcagtta
     1141 ctaactcgtc aactctgatt tatccaataa aattgaaaag gatggaaaaa aggataaatt
     1201 tatgatatac tttattttga agaccttatt agaaatcttg aaagagtatt gaaaacttag
     1261 aatgagaaaa attgttatca atggtggatt accactgcaa ggtgaaatca ctattagtgg
     1321 tgctaaaaat agtgtcgttg ccttaattcc agctattatc ttggctgatg atgtggtgac
     1381 tttggattgc gttccagata tttcggatgt agccagtctt gtcgaaatca tggaattgat
     1441 gggagctact gttaagcgtt atgacgatgt attggagatt gacccaagag gtgttcaaaa
     1501 tattccaatg ccttatggta aaattaacag tcttcgtgca tcttactatt tttatgggag
     1561 cctcttaggc cgttttggtg aagcgacagt tggtctaccg ggaggatgtg atcttggtcc
     1621 tcgtccgatt gacttacacc ttaaggcgtt tgaagctatg ggtgccactg ctagctacga
     1681 gggagataac atgaagttat ctgctaaaga tacaggactt catggtgcaa gtatttacat
     1741 ggatacggtt agtgtgggag caacgattaa tacgatgatt gctgcggtta aagcaaatgg
     1801 tcgtactatt attgaaaatg cagcccgtga acctgagatt attgatgtag ctactctctt
     1861 gaataatatg ggtgcccata tccgtggggc aggaactaat atcatcatta ttgatggtgt
     1921 tgaaagatta catgggacac gtcatcaggt gattccagac cgcattgaag ctggaacata
     1981 tatatcttta gctgctgcag ttggtaaagg aattcgtata aataatgttc tttacgaaca
     2041 cctggaaggg tttattgcta agttggaaga aatgggagtg agaatgactg tatctgaaga
     2101 cagcattttt gtcgaggaac agtctaattt gaaagcaatc aatattaaga cagctcctta
     2161 cccaggcttt gcaactgatt tgcaacaacc gcttacccct cttttactaa gagcgaatgg
     2221 tcgtggtaca attgtcgata cgatttacga aaaacgtgta aatcatgttt ttgaactagc
     2281 aaagatggat gcggatattt cgacaacaaa tggtcatatt ttgtacacgg gtggacgtga
     2341 tttacgtggg gccagtgtta aagcgaccga cttaagagct ggggctgcac tagtcattgc
     2401 tgggcttatg gctgaaggta aaactgaaat taccaatatc gagtttatct tacgtggtta
     2461 ttctgatatt atcgaaaaat tacgtaattt aggagcggat attagacttg ttgaggatta
     2521 aaccgtagag gtgtttatga atatttggac caaattagca atgttttctt tttttgaaac
     2581 ggatcgcttg tatttgcgtc ctttcttttt tagtgatagt caggacttcc gcgagatagc
     2641 ttcaaatcca gaaaatcttc aatttatttt cccaacgcag gcaagtctgg aagaaagtca
     2701 atatgcactg gccaattact ttatgaagtc ccctttggga gtgtgggcaa tttgtgacca
     2761 gaaaaatcaa caaatgattg gttctattaa atttgagaag ttagatgaaa tcaaaaaaga
     2821 agctgagctt ggctattttt tgagaaaaga tgcttggtcg caaggattta tgacagaggt
     2881 tgttagaaaa atttgtcagc tttcttttga ggaatttggc ttaaaacaat tatctatcat
     2941 tacccacctt gaaaatgaag ctagccaaag agttgctctt aagtctggat ttagtttgtt
     3001 ccgtcagttt aagggaagtg atcgttacac aagaaaaatg cgggattatc ttgaatttcg
     3061 gtatgtaaaa ggagagttca atgagtaagc atcaggaaat tctaagctat ttggaggaat
     3121 taccagtagg taaaagggtc agtgttcgta gcatttcgaa tcatctagga gttagtgatg
     3181 gaacagccta tcgggctatt aaagaagctg aaaaccgtgg aattgtggag acccgtccta
     3241 gaagtggaac aattcgtgtt aaatcccaga aagttgctat agagagatta acgtttgctg
     3301 aaattgcaga agtgacttct tctgaggttc tggctgggca agaaggttta gagagagagt
     3361 ttagtaagtt ttcaattggt gccatgactg aacaaaatat cttgtcttac cttcatgatg
     3421 gggggctctt gattgtcgga gaccgaaccc gtattcagtt gctagccttg gaaaatgaaa
     3481 atgcagttct ggttacaggg ggatttcagg ttcatgatga tgtgcttaaa ctggccaatc
     3541 aaaaagggat tcctgttcta agaagtaagc atgatacctt taccgtcgcg accatgatca
     3601 ataaagcctt gtcaaatgtc caaatcaaga ctgatattct gacagttgag aaactttatc
     3661 gccctagtca tgagtatggt tttctgagag agacagatac agttaaagat tatttggact
     3721 tggttcgtaa gaatcgtagc agccgtttcc ctgttatcaa tcaacatcag gtcgttgttg
     3781 gcgttgtaac catgagagac gctggtgata aatcaccaag cacgacaatt gataaggtta
     3841 tgtctcgtag tctatttttg gttgggttat cgacaaatat tgccaatgtg agtcaacgga
     3901 tgatcgcaga agactttgaa atggtaccag ttgttcgaag caatcaaact ttgcttggcg
     3961 ttgtgacgcg acgagatgtc atggagaaga tgagccgttc ccaagtttcg gctctaccaa
     4021 ctttttctga gcagattgga caaaagctct cttatcacca tgatgaagta gtcattacag
     4081 tggaaccctt tatgctagaa aaaaatggag ttttggctaa tggtgtattg gcagaaattc
     4141 tgacccacat gacccaagat ttagttgtta atagtggtcg caatctcatt atcgagcaga
     4201 tgctgatcta ctttttgcag gctgttcaga tagatgatat attgcgcatt caggcacgga
     4261 ttattcatca tacgagacgg tcagctataa ttgattacga tatttatcat ggtcaccaga
     4321 ttgtttcaaa agcaaatgtg actgttaaaa ttaattagaa actaggagaa aagatgataa
     4381 cattaaaatc agctcgtgaa atcgaagcta tggacaaggc tggtgatttt ctagcaagta
     4441 ttcatatagg cttacgtgat ttgattaagc caggcgtaga tatgtgggaa gttgaagaat
     4501 atgtccgccg tcgttgtaaa gaagaaaatt tccttccact tcagattggg gttgacggtg
     4561 ccatgatgga ctatccttat gctacctgtt gctctcttaa cgatgaagtg gctcacgctt
     4621 tccctcgtca ttatatcttg aaagatggtg atttgctcaa agttgatatg gttttgggag
     4681 gtcccattgc taaatctgac ctgaatgtct caaaattaaa cttcaacaat gttgaacaaa
     4741 tgaaaaaata cactcagagc tattctggtg gtttagcaga ctcatgttgg gcttatgctg
     4801 ttggtacacc gtccgaagaa gtcaaaaact tgatggatgt aaccaaagaa gctatgtaca
     4861 agggtattga gcaagctgtt gttggaaatc gtatcggtga tatcggtgcg gctattcaag
     4921 aatacgctga aagtcgtggt tacggtgtag tgcgtgattt ggttggtcat ggtgttggcc
     4981 caactatgca cgaagaacca atggttccta actatggtat tgcaggtcgt ggactccgtc
     5041 ttcgtgaagg aatggtctta accattgaac caatgatcaa tacaggcgat tgggaaattg
     5101 atacagatat gaaaactggt tgggcgcata agaccattga cggtggattg tcatgtcagt
     5161 atgaacacca atttgtcatt acgaaagatg gacctgttat cttgactagc caaggtgaag
     5221 aaggaactta ttaataaaaa gtgaaaagac tactggaagt ttattttgat aaaaaatcca
     5281 gtagatcttt tcataataaa acgcattgta tcaagtgtta ggggctgata tcatgcgttt
     5341 ttctgctttt aagatttttt ccaactctgt ttgtaagcgc atcataacaa agggtctagg
     5401 attcagggct ctcctcctat atactattag taaagtaaaa ctaagagagg atattttagt
     5461 gtcgcagtct attgttcctg tagagattcc acaatattgt cgttttgatt ctaaaaagag
     5521 aaatggaatt ctgtttaacg ttcgtattgc caatcttaaa tttacctttt ttagattaga
     5581 cttcctgcga aataaaatat ggtatagtag ttctatgaat gatgaagcaa gtaaacaact
     5641 aactgatgca cgatttaagc gtcttgttgg tgttcagcgc ac
//
LOCUS       DAVHBD010000073         5599 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000073 DAVHBD010000000
VERSION     DAVHBD010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.073"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            1..279
                     /locus_tag="VVK04_001994"
                     /pseudo
     CDS             1..279
                     /locus_tag="VVK04_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            434..634
                     /locus_tag="VVK04_001995"
     CDS             434..634
                     /locus_tag="VVK04_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990605.1"
                     /translation="MVVSASASSTSPQAQEQVDKSELRALSQELDQHLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            659..1075
                     /locus_tag="VVK04_001996"
     CDS             659..1075
                     /locus_tag="VVK04_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990606.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVISFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1306..2013
                     /gene="ccdA2"
                     /locus_tag="VVK04_001997"
     CDS             1306..2013
                     /gene="ccdA2"
                     /locus_tag="VVK04_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU3990607.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2024..2581
                     /gene="sdbB"
                     /locus_tag="VVK04_001998"
     CDS             2024..2581
                     /gene="sdbB"
                     /locus_tag="VVK04_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU3990608.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2956..4347
                     /locus_tag="VVK04_001999"
     CDS             2956..4347
                     /locus_tag="VVK04_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU3990609.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4490..5407
                     /gene="adcAII"
                     /locus_tag="VVK04_002000"
     CDS             4490..5407
                     /gene="adcAII"
                     /locus_tag="VVK04_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU3990610.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5415..>5599
                     /locus_tag="VVK04_002001"
     CDS             5415..>5599
                     /locus_tag="VVK04_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU3990611.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSK"
BASE COUNT         1704 a          988 c         1186 g         1721 t
ORIGIN      
        1 ttaaagcacc tagcacctgt ttagattgac gaaacaggat tcgatactta tttttatcga
       61 gaatatggtc gctcattaaa aggtcagtta agaagaggca aagtatctgg aagaagatat
      121 cagagaattt ctttggttgc aggtctaaca aatggtgagt taatcgctcc aatgacctac
      181 gaagagacga tgacgagcga cttttttgaa gcttggtttc agaaatttct cttaccaaca
      241 ttaaccacac catcggttat tatattaaaa cgaaataaga ataggacaaa tcgatcagga
      301 cagtaaaatc gaattctaac aatgttttag aagtccatat gtactattct agtttcaata
      361 taccataact gctcctagtc aacctgcaag tcctgtccca gctccaagct cagctccgac
      421 tcaagatcct agagtggtag taagcgcttc ggctagctca acgagcccac aagctcaaga
      481 gcaagttgac aagtctgaac ttcgtgcctt gagtcaagag ttagaccaac acttgaaagc
      541 tttggcaaca gtatctgatc cgaaaatcga tgcaaccaag gctgtcctcc tagatgctca
      601 aaaagctccg gaagatagtg ccttgacaga gtaaggtctg catactgcag tagagtctgt
      661 gaaggctgcc ttggactctc tcaaagatgt gaaagcaaat gctagcgaca gcaagcctgc
      721 acaggacaag aaggatgcaa aacaaggaac ggaagatagt aaggattcag ataagatgac
      781 tgaaacaaac tcagttccgg caggagtgat tgtggtcagt ctacttgccc tcctaggcgt
      841 gatttccttc tggctgattc gccgtaagaa agagtcagaa atccagcaat taagcacgga
      901 attaatcaag gttctaggac agctagatgc agaaaaagcg gataaaaaag tccttgccaa
      961 agcccaaaac cttctccaag aaacccttga tttcgtgaaa gaagaaaatg gctcagcaga
     1021 gacagaaact aaactagtag aggagcttaa agcaatcctt gacaaactca agtaaaacat
     1081 gatttatgaa atgtcagact taaaagacat tttcgttcac aaaagcagcg acgagtaatc
     1141 cttgtcgttg ctttttggct attttggggg ataagatccg ccttgactag caaaagaaaa
     1201 gattggtcca atagtgcccg atacgatttt gcgtagcaga aagcttacaa ataaaattga
     1261 atatagtaaa ataggattag aattattaag aaagttggtt ctttattgga aacgatagta
     1321 tttttaatct ctgtttttct agcaggtgtt ttatcctttt tttctccttg tatttttcct
     1381 cttctgccag tctatgctgg gattttattg gatgatcaag aaagtgcaaa aagcttttct
     1441 ttgtttggga gaaaggttct ctggtcaggc ttgattcgaa cactttgctt tatcgctggt
     1501 atctctctca ttttctttat tctaggcttt ggtgctggtt actttggtca tattctctat
     1561 gcaaattggt ttcgatatgg catgggagct attattatca ttttgggtct tcaccagatg
     1621 gaaatttttc atttgaagaa attagaagtt caaaaaagtt ttacctttaa aaaatcagat
     1681 tctaatcgtt attggtcagc ttttttactt ggtattacct ttagctttgg ttggacacct
     1741 tgtattggtc cagttttaag ttctgtttta gcacttgcgg cttctggagg caatggcgct
     1801 tggcaaggag cgatttatac tctcatttac actctgggca tggcccttcc tttcttggta
     1861 ttggcactag cttcaggtct agtcatgcca tattttagta aaatcaagcg tcatatgatg
     1921 ctactaaaga aaattggtgg tttcctcatt gttttaatgg gaattttgtt actattagga
     1981 caagtaaatg ttctagctgg aatttttgaa taaaggagga caaatgaaaa aagtaatgtt
     2041 tgctggctta agtctcttgt cattagttgt attgatggcc tgtggtgagg aagaaactaa
     2101 aaagactcaa gcagcacaac agccaaaaca acaaacgact gtacaacaaa ttgctgttgg
     2161 aaaagatgct ccagacttca cattgcaatc catggatggc aaagaagtta agttatctga
     2221 ttttaagggt aaaaaggttt acttgaagtt ttgggcttca tggtgtggtc catgcaagaa
     2281 aagtatgcca gagttgatgg aactagcggc gaaaccagat cgtgatttcg aaattcttac
     2341 tgtcattgca ccaggaattc aaggtgaaaa aactgttgag caattcccac aatggttcca
     2401 ggaacaagga tataaggata tcccagttct ttatgatacc aaagcaacca ccttccaagc
     2461 ttatcaaatt cgaagcattc ctacagaata tttaattgat agccaaggaa agattggaaa
     2521 gattcaattt ggtgctatca gtaatgcgga tgcagaagca gcatttaaag aaatgaacta
     2581 gaatcgataa aatctgatta caagatgtag tcagattttg gtaacttcta aaactaactt
     2641 ctagtttccc acaacctagc ttttagtatg agaaaaacgt gtgacaccag tggaaatccg
     2701 tcttagacta acttccactg gttttctttt tcttgatata taagggttca aaagcgaaaa
     2761 gactcagaaa aaagtgcacg acaaatagcc ctaaaacaga gtcgttttag agtaacttcc
     2821 agttttggga gagagatgga agttactttg agaagttacg gtagtcagat ttttttagaa
     2881 aaacatttta taaatattca catatctcct atatttatgg taaaatagaa tcatcagttt
     2941 attttggagt caaagatgaa tatatttaga acaaagaatg ttagtttaga taaaacagag
     3001 atgcataggc atttgaagtt atgggatttg attttgctgg gtattggagc catggtaggg
     3061 acaggtgtct ttacaatcac aggtactgca gctgctacac ttgctggtcc agcactagtg
     3121 atttcaatcg ttatttctgc cttgtgtgtg ggattatcag ccctcttttt tgcagaattt
     3181 gcctcgcgag tacccgctac aggaggtgcc tatagttacc tctatgctat cttaggagaa
     3241 ttccctgcct ggttggctgg ttggttaacc atgatggagt tcatgacagc catatcaggc
     3301 gtagcttcgg gttgggcagc ttattttaaa ggcttgctct ctcaatacgg gatagccctt
     3361 cctcaggctt taaatggtac ctttaatcct caagcaggga catttgttga tttattgcct
     3421 attcttgtct tggtcttggt gacttcgctt gttttactaa atgccaaggc agccttacgc
     3481 tttaattcga ttctagttat tttgaaattt tccgctttag ctctctttgt tttagtagga
     3541 atttggaata ttaagtttga taattggagc aattttgctc cttacggttt tggacaaatc
     3601 tatggagcta gtactggtat tatggctggt gcgtccttga tgttcttcgg ttttttggga
     3661 tttgaatcca tctctatggc tgtagatgaa gtcaagactc ctcaaaaaaa tattcctaga
     3721 gggattgtct tatcgctttc tatcgtaacc attctctatg ccttggtgac ccttgttttg
     3781 actggtgtgg ttcactatag tcatttaaat gtcgatgatg ccgttgcctt tgcccttcgt
     3841 agtgttggga ttagttgggc agccaactat gtgtcattag tggctatctt gaccttgatt
     3901 acagtttgta tttcgatgac ctatgcccta tcgcgtatga tttacagttt agcacgtgac
     3961 ggcttagtgc ctgctgcctt taaggaactg acgaagacta gcaagatacc aaagaatgct
     4021 actatcttga caggtctagc ttcagcagta gcagcaggaa tgttcccact agccagtatt
     4081 gcagcctttt taaatatttg taccttagcc tacttgatca tgttggctta tggtctgatt
     4141 cgcttacgga aagaaaaagg aatgcccaaa gctggggaat ttaaaacacc attggtacct
     4201 ctgttaccaa ttttatcgat catcatttgt ttatccttca tgttacagta taatatgaat
     4261 acctggattg ctttcctagt tgcgttgtta gtaggaagta ttatttactt cacttatggc
     4321 tataagcatt ctaccataga agaataaagt gaaagtctat tgagttgttg gcactcagca
     4381 gatttttata tgtgaaagaa atttcaaatt ttttctaaaa atatcttgac agattaaatt
     4441 ttcaggagta gaatatttac tagttaatta aatggttaag gagttgttca tgaagaaaca
     4501 aaatttattt ttagtcctgt taagtgtctt tcttttgtgc ttgggggctt gtggtcaaaa
     4561 ggaaagtcag acaggaaagg ggatgaaaat tgtgaccagt ttttatccta tctacgctat
     4621 ggttaaggaa gtatctggtg acttgaatga tgttcggatg attcagtcaa gtagtgggat
     4681 tcactccttt gaaccttcgg caaatgatat cgcagccatc tatgatgcag atgtctttgt
     4741 ttaccattct catacactcg aatcttgggc aggaagtctg gatccaaatc taaaaaaatc
     4801 caaagtgaag gtcttagagg cttctgaggg aatgaccttg gaacgtgtcc ctggactaga
     4861 ggatgtggaa gcaggggatg gagttgatga aaaaacgctc tatgaccctc acacatggct
     4921 agatcctgaa aaagctggag aagaagccca aattatcgct gataaacttt cagaggtgga
     4981 tagtgagcat aaagagactt atcaaaaaaa tgcgcaagcc tttatcaaaa aagctcagga
     5041 attgactaag aaattccaac caaaatttga aaaagcgact cagaaaacat ttgtaacaca
     5101 acatacagcc ttttcttatc tagcgaagag atttgggctt aatcaacttg gtattgcagg
     5161 tatctctcct gaacaagaac caagtccacg acaactaaca gaaattcagg aatttgttaa
     5221 gacctataag gttaaaacga tttttacaga aagtaacgct tcttcaaaag tagctgaaac
     5281 tcttgtcaaa tcaacaggtg tgggtcttaa aactctgaat cctttagagt cagacccaca
     5341 aaatgacaag acctatttag aaaatcttga agaaaatatg agtattctag cagaagaatt
     5401 aaagtgagga aagaatgaaa atcaataaaa aatatctagc aggttcagtg gcagtccttg
     5461 ccctaagtgt ttgttcctat gaacttggtc gtcaccaagc tggtcaggtt aagaaagagt
     5521 ctaatcgagt ttcttatata gatggtgatc aggctggtca aaaggcagaa aatttgacac
     5581 cagatgaagt cagtaagag
//
LOCUS       DAVHBD010000074         5188 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000074 DAVHBD010000000
VERSION     DAVHBD010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.074"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            321..1866
                     /locus_tag="VVK04_002002"
     rRNA            321..1866
                     /locus_tag="VVK04_002002"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1918..1990
                     /locus_tag="VVK04_002003"
     tRNA            1918..1990
                     /locus_tag="VVK04_002003"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1951..1953,aa:Ala,seq:tgc)
     gene            2115..5016
                     /locus_tag="VVK04_002004"
     rRNA            2115..5016
                     /locus_tag="VVK04_002004"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5093..>5188
                     /gene="rrf"
                     /locus_tag="VVK04_002005"
     rRNA            5093..>5188
                     /gene="rrf"
                     /locus_tag="VVK04_002005"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1466 a         1050 c         1517 g         1155 t
ORIGIN      
        1 cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt cgaatcccgt
       61 acggactatg gtatgttgcg gttggaacac ttgatgaaaa aaagtttaaa aaaacttaaa
      121 aatcttcaaa aaagtgttga caattgaaag tggctgtgat atactaatat agttgtcgct
      181 tgagagaagc aagtgacaaa gacctttgaa aactgaacaa gacgaaccaa tgtgcagggc
      241 gctacaacat aagttgtagt actgaacaat gaaaaaaaca ataaatctgt cagtgacaga
      301 aatgagtgag aactcaaact tttaatgaga gtttgatcct ggctcaggac gaacgctggc
      361 ggcgtgccta atacatgcaa gtagaacgct gaaggaggag cttgcttctc tggatgagtt
      421 gcgaacgggt gagtaacgcg taggtaacct gcctggtagc gggggataac tattggaaac
      481 gatagctaat accgcataag agtagatgtt gcatgacatt tgcttaaaag gtgcacttgc
      541 atcactacca gatggacctg cgttgtatta gctagttggt ggggtaacgg ctcaccaagg
      601 cgacgataca tagccgacct gagagggtga tcggccacac tgggactgag acacggccca
      661 gactcctacg ggaggcagca gtagggaatc ttcggcaatg gacggaagtc tgaccgagca
      721 acgccgcgtg agtgaagaag gttttcggat cgtaaagctc tgttgtaaga gaagaacgag
      781 tgtgagagtg gaaagttcac actgtgacgg tatcttacca gaaagggacg gctaactacg
      841 tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc cggatttatt gggcgtaaag
      901 cgagcgcagg cggttagata agtctgaagt taaaggctgt ggcttaacca tagtaggctt
      961 tggaaactgt ttaacttgag tgcaagaggg gagagtggaa ttccatgtgt agcggtgaaa
     1021 tgcgtagata tatggaggaa caccggtggc gaaagcggct ctctggcttg taactgacgc
     1081 tgaggctcga aagcgtgggg agcaaacagg attagatacc ctggtagtcc acgctgtaaa
     1141 cgatgagtgc taggtgttag accctttccg gggtttagtg ccgtagctaa cgcattaagc
     1201 actccgcctg gggagtacga ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca
     1261 caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac
     1321 atccctctga ccgctctaga gatagagttt tccttcggga cagaggtgac aggtggtgca
     1381 tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaacccc
     1441 tattgttagt tgccatcatt tagttgggca ctctagcgag actgccggta ataaaccgga
     1501 ggaaggtggg gatgacgtca aatcatcatg ccccttatga cctgggctac acacgtgcta
     1561 caatggctgg tacaacgagt cgcaagccgg tgacggcaag ctaatctctt aaagccagtc
     1621 tcagttcgga ttgtaggctg caactcgcct acatgaagtc ggaatcgcta gtaatcgcgg
     1681 atcagcacgc cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacaccacga
     1741 gagtttgtaa cacccgaagt cggtgaggta accgtaagga gccagccgcc taaggtggga
     1801 tagatgattg gggtgaagtc gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc
     1861 tcctttctaa ggataaggaa ctgcgcattg gtcttgttta gtcttgagag gtcttgtggg
     1921 gccttagctc agctgggaga gcgcctgctt tgcacgcagg aggtcagcgg ttcgatcccg
     1981 ctaggctcca ttggtgagag attaccaagt aatgcacatt gaaaattgaa tatctatatc
     2041 aaatagtaac aagaaaataa accgaaaacg ctgtagtatt aataagagtt tatgactgaa
     2101 aggtcagaaa ataaggttaa gttaataagg gcgcacggtg gatgccttgg cactaggagc
     2161 cgacgaagga cgtgacaaac gacgatatgc cttgggtagc tgtaagtaag cgatgatcca
     2221 gggatttccg aatgggggaa cccaacaggt aatacctgtt acccacatct gttaaggatg
     2281 tgaggaggaa gacgcagtga actgaaacat ctaagtagct gcaggaagag aaagcaaaag
     2341 cgattgcctt agtagcggcg agcgaaacgg cagaagggca aaccgaagag tttactcttc
     2401 ggggttgtag gactgcaatg tggactcaaa gattatagaa gaatgatttg ggaagatcag
     2461 ccaaagagag taatagcctc gtatttaaaa tagtctttgt acctagcagt atcctgagta
     2521 cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc atctcccaac cctaaatact
     2581 ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg tgaaaagcac cccgggaggg
     2641 gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt cgagcccgtt aatgggtgag
     2701 agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg atgcgaggtt aagttgaaga
     2761 gacggagccg tagggaaacc gagtctgaat agggcgcctt agtatcatga cgtagacccg
     2821 aaaccatgtg acctacccat gagcaggttg aaggtgcggt aagacgcact ggaggaccga
     2881 accagggcac gttgaaaagt gcttggatga cttgtgggta gcggagaaat tccaaacgaa
     2941 cttggagata gctggttctc tccgaaatag ctttagggct agcgtcgaca ttagagattc
     3001 ttggaggtag agcactgttt gggtgagggg tccatcccgg attaccaatc tcagataaac
     3061 tccgaatgcc aatgaattat ggtcggcagt cagactgcga gtgctaagat ccgtagtcga
     3121 aagggaaaca gcccagacca ccagctaagg tcccaaaata attgttaagt ggaaaaggat
     3181 gtggggttgc acagacaact aggatgttag cttagaagca gctattcatt caaagagtgc
     3241 gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt accggggcta aaacaattta
     3301 ccgaagctgt ggataccttt ataggtatgg taggagagcg ttctatgtgt gatgaaggta
     3361 taccgtgagg agtgctggaa cgcatagaag tgagaatgcc ggtatgagta gcgaaagaca
     3421 ggtgagaatc ctgtccaccg taagactaag gtttccaggg gaaggctcgt ccgccctggg
     3481 ttagtcggga cctaaggaga gaccgaaagg tgtatccgat ggacaacagg ttgatattcc
     3541 tgtactagag tatgtagtga tggagggacg cagtaggcta actaaagcag acgattggaa
     3601 gagtctgtct aagcagtgag gtgtgaattg agtcaaatgc ttaattctat aacattgagc
     3661 tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt cacactgcca agaaaagctt
     3721 ctagcgttta aacatactct acccgtaccg caaaccgaca caggtagtcg aggcgagtag
     3781 cctcaggtga gcgagagaac tctcgttaag gaactcggca aaatgacccc gtaacttcgg
     3841 gagaaggggt gctgacttta agtcagccgc agtgaatagg cccaagcaac tgtttatcaa
     3901 aaacacagct ctctgctaaa tcgtaagatg atgtataggg ggtgacgcct gcccggtgct
     3961 ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga attgaagccc cagtaaacgg
     4021 cggccgtaac tataacggtc ctaaggtagc gaaattcctt gtcgggtaag ttccgacccg
     4081 cacgaaaggc gtaatgattt gggcactgtc tcaacgagag actcggtgaa attttagtac
     4141 ctgtgaagat gcaggttacc cgcgacagga cggaaagacc ccatggagct ttactgcagt
     4201 ttgatattga gtgtctgtac cacatgtaca ggataggtag gagtctaaga gatcgggacg
     4261 ccagtttcga aggagacgct gttgggatac tacccttgtg ttatggccac tctaacccag
     4321 ataggtgatc cctatcggag acagtgtctg acgggcagtt tgactggggc ggtcgcctcc
     4381 taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg ttggaaatca ttcgcagagt
     4441 gtaaaggtat aagggagctt gactgcgaga gctacaactc gagcagggac gaaagtcggg
     4501 cttagtgatc cggtggttcc gtatggaagg gccatcgctc aacggataaa agctaccctg
     4561 gggataacag gcttatctcc cccaagagtt cacatcgacg gggaggtttg gcacctcgat
     4621 gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg gttgggctgt tcgcccatta
     4681 aagcggcacg cgagctgggt tcagaacgtc gtgagacagt tcggtcccta tccgtcgcgg
     4741 gcgtaggaaa tttgagagga tctgctccta gtacgagagg accagagtgg acttaccgct
     4801 ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct atgtagggaa gggataaacg
     4861 ctgaaagcat ctaagtgtga aacccacctc aagatgagat ttcccatgat tatatatcag
     4921 taagagccct gagagatgat caggtagata ggttagaagt ggaagtgtgg cgacacatgt
     4981 agcggactaa tactaatagc tcgaggactt atccaaagta actgagaata tgaaagcgaa
     5041 cggttttctt gatttgaata gatattcaat tttgagtagg tattactcag agttaagtga
     5101 cgatagccta ggagatacac ctgtacccat gccgaacaca gaagttaagc cctagaacgc
     5161 cggaagtagt tgggggttgc cccctgtg
//
LOCUS       DAVHBD010000075         5186 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000075 DAVHBD010000000
VERSION     DAVHBD010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5186
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.075"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..757)
                     /locus_tag="VVK04_002006"
     CDS             complement(<1..757)
                     /locus_tag="VVK04_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU3990612.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIADKWYYFD"
     gene            complement(761..1093)
                     /locus_tag="VVK04_002007"
     CDS             complement(761..1093)
                     /locus_tag="VVK04_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU3990613.1"
                     /translation="MQQITEIIIAFATSFLTVAVGGIVKAVKDYLLRKGGEKAVIIAE
                     ILAKNAVHAVEQVTSETGYKGEEKLEQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            complement(1097..1513)
                     /locus_tag="VVK04_002008"
     CDS             complement(1097..1513)
                     /locus_tag="VVK04_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEU3990614.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLFRKISGVLLLMILIPASVLLPEKTGFAFLYSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            complement(1522..1872)
                     /locus_tag="VVK04_002009"
     CDS             complement(1522..1872)
                     /locus_tag="VVK04_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990615.1"
                     /translation="MAETNQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            complement(1875..2078)
                     /locus_tag="VVK04_002010"
     CDS             complement(1875..2078)
                     /locus_tag="VVK04_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990616.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(2059..3395)
                     /locus_tag="VVK04_002011"
                     /pseudo
     CDS             complement(2059..3395)
                     /locus_tag="VVK04_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
BASE COUNT         1342 a         1201 c          956 g         1687 t
ORIGIN      
        1 catcaaaata gtaccacttg tcagcgattt tcttccagcc tgtggccatt tcgcctgatt
       61 ggtcaaagta gtaccaatta ccgtctgtgt gcttcttcca gcggtctgaa agcatatagc
      121 ctgagccatc gaaataatac caggtaccgt tgattttctc aaacttatct tttggataag
      181 agccgtctga atgtacgtac cagtagccag tgccattttt ctgccagcct gttgcagcgc
      241 tcaagccgtt ttcgatgtct tgcttaaact gttcacggct aatgccccaa cttgcaagat
      301 atggatatgg atccacatgg tctgagtggt tgtttggttg gttattggta cagtattcat
      361 gcgtcttgat acctgccaag tcgtctgtat caagagtctt cggcaagcct gcttcgtccg
      421 ctagattgcg tagcaattcg atatagaggc gatagtcagc cataaactct tccttagttg
      481 aatggctttc aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacat
      541 cccaacttcc gttgttcaca ggacctactt gcatgacacg gccgtttccg acaacatgtg
      601 aaaagaaccc tagttcaggg tcctttctat agtggtaatc agcttcattt tgtgcggttg
      661 agtttcgatt tcctgttgag tgagcatgta cttgtcgata aggctgcacc ccaacctggg
      721 gcaagcctgt acgtagtctg tttctatcga tatccattcc ctatcgtcct ttccatgcgt
      781 cgttcatctg tttcactgct gactctacga aggtgtctaa gtctttgtca gtcatgctaa
      841 tattgtattt tgtaagctca gcacggactt tagcacgagc ctgctccagc ttttcttcgc
      901 ccttatagcc agtctctgag gtaacctgct caacggcatg aactgcattt ttagctagaa
      961 tttcagcgat gatcaccgct ttctctccgc ctttacgcaa aagataatct tttactgctt
     1021 ttacaatacc gcctactgct actgttaaaa agcttgtcgc aaaagcaatg atgatttcag
     1081 taatttgttg catatgttat tctccttttt tcgtgtcatc atctttttca agtaatcgct
     1141 gaaatacttt tacaatcggc tgaaaaagag taacatttcc ttttaatttg cggtaatttt
     1201 caatgagaga ttgaaaagta aatgcgatgt acccgagata gattgagtac aagaatgcaa
     1261 aacctgtctt ttcaggcaac aaaacggacg ccggaatgag gatcatcagt aagagaaccc
     1321 ctgaaatctt acgaaatagc ccattgatgc cgattttgct cttgtactcg atgtcaggat
     1381 tgataatcgc cgcaatcgtc cctgtcacaa aatcaatgat ttccattgag acaatcagtg
     1441 ctagagcgta caaaaccaaa ccatcttcag tctgtacgac acttcttaga aaattgaaaa
     1501 attcaatttg catacaacct cctattcttt aggttctacc gttggaaccg tccagtcagg
     1561 attgccctct gcatcaaatt tcatgatata gaattcatga ttcaacagaa cggctacgtt
     1621 gattgttgcg attgtaccac cccactggtt gaacgcccaa acggtttcaa catccttgaa
     1681 ttggcgacgg ccatttacga tcacaggacg tttttgaacg tcacgataca tatagaagtc
     1741 atcgcttaca ttcttgcaac gaatgaactc tccattttct ttcatgtagc gcaaagcgct
     1801 cgcaagatca aatggttctg tgatttttgt aaggtctagt aagttatctg tgttttgatt
     1861 tgtttctgcc atgtctattc tcctttgtct gctggtttag tttgttcatc aagcagagct
     1921 tccagctcat ccactcgtgc ttgaagtctt tgattctctt ccctttgctc attcaactga
     1981 atactcaaga tattacttgt aatcatcgaa tttgttgaag ttgttgacat ttcactaatt
     2041 gtcatttgta aggcttggtt aagctgttct gtgttcattt tctaagttct ccaatctgtg
     2101 tgttcgtttt ctattttcaa gagcaagctc ctaaattgct ttaagtgcga tattggtcaa
     2161 catgttgtta ttcatgctat tgttttctcc attttttcta ttttttgatt taattcttga
     2221 atagccttga ttaagtaagg aactaaagcg gtatagtcta tatgcagata gccatctgga
     2281 ttctcaggat ctcgtgagac aattcttgga acgatggttt cagcctcttg agctattaga
     2341 ccaatctcct catgtttctt actttcgatg aaatcaaatg caaccattct taatctgttg
     2401 attttgtcca aggctttcac agctgtatct gtgatgttct cttttaagcg tctgtctgat
     2461 ttttgttcca tccaatactt cacgctaccg ctaccgacct gattccacca aacaaccgca
     2521 ttccttccgc ctttgggatt ccaaccatca ccaagcacat ctttacttcc aagttcgata
     2581 ccatttgaaa acacaggaga acgagaaaaa gtagtattcc catagaagtt tgctctcgat
     2641 gaattcgaaa aatccacttg atcataaaaa ccgacttcat tcctacagta cattttccca
     2701 tcagtattga cgttccatgc tttaggtccg gcatagttcc aattatttcc ccagttcgcc
     2761 cagaaggctg tccggactcc atacccggca ccattcccca taccaacaga gaactgattg
     2821 acacctgaaa tccagcgacc gccaccctgg tcaaattgac caagtgtgaa tccaccgatt
     2881 cggccttgat aggcttctag gaaggttgag ctagaaatga cggactcaac cttagtagag
     2941 aagatacgtt tagatatcag ttggtcaata aaagcatcat ttgcagttaa ttttctaata
     3001 agcgcattgt caactttcaa cttctcagca gttaccgctt cagcgtctaa tatcgtagtc
     3061 gtgaccgaac cagcttcaaa attggccgtt ttgagcttat caaccatggc agacttgatg
     3121 actgctctgt caatcagggt ctctccagtg atgtgggtca atttcccaac gaagcggtta
     3181 tgtccattgg cgccaagatt gattccagag atgatatctc cagccgagtt gatgttttga
     3241 actgcccatg agccagttag ttggctttga acagagcgaa tcgcttcgtc cgtgtcttca
     3301 ggagcttctt tgtagtccgt cgcgacagaa cctctttcga gttgaacatc tgtaacatag
     3361 aggttgatgg tcttcccttt ttcaccaaac aacatcaaat tcagattctc tacatcgtct
     3421 gataaagtaa acgtaaatgt gaaacgctta tacttcgatg ttatttgtgg acttgggata
     3481 ttttgccact cttgcccaat aatgtttttg tttttgatgt agtgcaaagc gactttcaag
     3541 ccactgttgc tatcgccacc atctttcgaa acaagcagag atacactaac cttttcccct
     3601 cgaataccat caaatgcaaa agattgctga attccaaaaa aattagcaac atcttgagaa
     3661 tcgtgataga agtgtagtcc tggacgattt cgattattag gattttgaga gtgttgatag
     3721 ttgaaattca aaccaaaatt aacagattga tattcaagcc agtttttcga accgttctta
     3781 aattgaccat ttctgatata atttcgacca cctttggcaa ccttcccaac ctcaacctga
     3841 aatagttgat tagtcagagc catacgagca accttatccg caattccatt ttcagtattg
     3901 cccaaaatcc gctcgtaaag tttactggtt tccttaacac gctggaagtc agtagtctct
     3961 acttttcgcg ctagttgatt ggtcacattc acaaattgac tatcagcatt cgctttgttt
     4021 gcagaaacct gatcagatat tctacccatt tgtcgttcag cattatcctt gtttgtagcg
     4081 acctgagtct ttaaatttga aatctgatta tctgtgcctt gcttattact gtttatccga
     4141 tttgaaatat ttgaaatctg agtagtggtt ccttgctcac tgcttgtaag tctatttgat
     4201 agaccactga tttgaccgcc cacatcttgc ttataagtag ttatctgact tgaaatatcc
     4261 gtgaacttac catctacaga ttgacgatag ctagcgattt gactagcgat gtctttattc
     4321 gcactagttt taacagcttc aatcctctga ttaataccct taacatcttc ttgataagta
     4381 gccttaccaa cgaaatcacg attgaccagc tcacggactg ctgtcgcttg tctcgcgctc
     4441 tcctcacgag tatagcgctg tagggcttcc tgtcgctgac cgtctttatt tacatattcc
     4501 tgaatagctg ataagtcggt tcgcaagccc tgagctgtcc gctcaaaggt agccttagcc
     4561 tcagtgatga gaccatcagc gtcctcaggc gcaggactcc agtccgtcgc cacactaccg
     4621 atttcaacct tgattcctgt tacccaagct gtaccgcttg tagcaccttc aagattgaat
     4681 cgcaatgatg tcttcaattg atcaaaattt gttttttcag agtagtcata agtgaatgta
     4741 atatatttcc aatctgccga acctttatac ataccaagcg tagcataatc tggaccactc
     4801 tgtactccgg tctcactatt ttttctaaaa agataatgtt tgaagcaatt aaatacattc
     4861 caaaaatttc gaccttggac tacattttcg tacttgatcc aagcgctaaa agtaactttt
     4921 tggtacaacc ttgagctgaa atctggttca aggttgaacg ttaaagtaga gttgttctct
     4981 agcctatagc attctttttg acctgtgacg tggttttcag gtaatttttc aattacagct
     5041 ccaaccgtct tggattttat ccatagattc cgtcctccca ccttcatttt tgaaaattct
     5101 tcacgcaatt tcccagcttc agatacaact aaagtcttat ctgctttatc cttggttgcg
     5161 ttcaggattt cctgacggat agagcc
//
LOCUS       DAVHBD010000076         4848 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000076 DAVHBD010000000
VERSION     DAVHBD010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.076"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            21..866
                     /locus_tag="VVK04_002012"
     CDS             21..866
                     /locus_tag="VVK04_002012"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU3990617.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1013..2074)
                     /gene="dinB"
                     /locus_tag="VVK04_002013"
     CDS             complement(1013..2074)
                     /gene="dinB"
                     /locus_tag="VVK04_002013"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU3990618.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            2422..4746
                     /gene="pflB"
                     /locus_tag="VVK04_002014"
     CDS             2422..4746
                     /gene="pflB"
                     /locus_tag="VVK04_002014"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU3990619.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT         1410 a          996 c          962 g         1480 t
ORIGIN      
        1 tataatatag ggagtaatct atgtatctta ttgaaatttt aaaatctatc ttcttcggga
       61 ttgttgaagg aattacggaa tggttgccga tttccagtac aggtcacttg attttagcag
      121 aggaattcat ccaataccaa aatcaaaatg aagcctttat gtccatgttt aatgtcgtga
      181 ttcagcttgg tgctatttta gcagttatgg tgatttattt taacaagctc aatcctttta
      241 aaccgactaa ggacaaacag gaagttcgta agacttggag actatggttg aaggtcttga
      301 ttgctacttt acctttactt ggtgtcttta aatttgatga ttggtttgat acccacttcc
      361 ataacatggt ttcagttgct ctcatgttga ttatctacgg ggttgccttc atctatttgg
      421 aaaagcgcaa taaagcgcgt gctatcgagc caagtgtaac agagttggac aagcttcctt
      481 atacgaccgc tttctatatc ggactcttcc aagttcttgc tcttttacca gggactagcc
      541 gttcaggtgc aacgattgtc ggtggtttgt taaatggaac cagtcgttca gttgtgacag
      601 aatttacctt ctatcttggg attcctgtta tgtttggagc tagtgcctta aagattttca
      661 aatttgtgaa agccggagaa ctcttgagct ttgggcaatt gtttttgctc ttggtcgcga
      721 tgggagtagc ttttgcggtc agcatggtgg ctattcgctt cttgaccagc tatgtgaaaa
      781 aacacgactt cacccttttt ggtaaatacc gtatcgtgct tggtagtgtt ttgctacttt
      841 acagttttgt ccgtttattt gtataagaaa aaccttgaag gggcaactct tcaaggtttt
      901 atactcttcg aaaatctctt caaaccgcgt cagctttatc tgcaacctca aaacagtgtt
      961 ttgagcagcc tgcggctagc ctcctagttt gctctttgat tttcattgag ctttaaaatc
     1021 cagtcatggt aatccccaat aggcggacac ctctttcttt cttgcttaat tcttcataga
     1081 gttgcagggc tatttggctt atctgactag catcttgtgt tttttgagca agactttttc
     1141 gtttggtaag agttgaaaag tcctcgtagc ggattttcaa aatgacaatt tttccagctt
     1201 tttcttgttg atgtagattg agagcgactt tttctgatag aagagtcagc tcttttttga
     1261 tatcttcctc agcaaggaga atcttcccgt aggttttctc cttgccgatt gatttacgga
     1321 tgcgattgga tttgactgga gagttgtgaa tgccacgagc ctttcgatac agatcatagc
     1381 ctagtctacc aaaacggtct attagggtta cctcaggaac ttcaagtaaa tcagcaccag
     1441 taaaaacgcc catttgatga agacgttcta ctgtcttttt tcctactcca tgaaatttgg
     1501 aaatatccat ttgtttgaga aaatcctcag cctgttcagg tagaatcact gtcaaaccat
     1561 gtggtttttg ataatcactc gccattttag ctaagaattt gttgtaagaa acgcctgcgg
     1621 aagcagttag atggagttct tgccagatat ctttttgaat gaggcgagca attttgaccg
     1681 ctgacttgat accgagttta ttttctgtca catccaaata ggcttcgtca atgctcatgg
     1741 gttcaatcaa atctgtatag cgcttaaaaa tagctcgaat ctggagtccc acagacttgt
     1801 atttctcata attccctgag ataaagacag cctggggaca acgttcataa gcttccttgg
     1861 aactcatggc agaatggaca ccaaaagctc ttgcctcata actacaggta gaaacgactc
     1921 cccgtccacc tgtttgccga gggtcgcttc caataatgac aggttttcct ctgagtttag
     1981 gattatccct gatttccact gcagcaaaaa aggcatccat gtcaatatgg atgatttttc
     2041 ttgacaaatc atttaacaaa ggaaaaatca acatgcctag caccttttta tactcttcga
     2101 aaatctcttc aaaccacgtc agctctatct gcaacctcaa aacagtgttt tgagcaatct
     2161 gcggctagct tcctagtttg cttttcgatt tccattgagt gttactgctt attttctttt
     2221 attataccct tttttctgaa aaaaagaaaa aaggacttta ttttttcaaa aatataatac
     2281 agtttgaaat aaaatatata ctgttttaga aaagaaagtg taaaaatagg gaattttcac
     2341 ttgttgaaat cggttactat atggtatact tgtcttatga atgtaacaga tgactgttac
     2401 tagaaaaaag aggacattaa tatggttgtt aagacagttg ttgaagcaca agatattttt
     2461 gacaaagctt gggaaggctt caaaggcgta gattggaaag aaaaagcaag tgtatcacga
     2521 tttgtacaag ctaactacac accttatgat ggagacgaaa gcttccttgc aggaccaaca
     2581 gagcgttcac ttcacatcaa gaaaattgta gaagaaacta aagcacacta cgaagaaact
     2641 cgtttcccaa tggacactcg tccaacatct atcgctgata tccctgctgg atttatcgac
     2701 aaagaaaatg aagttatctt cggtatccaa aacgatgaac tcttcaaatt gaacttcatg
     2761 ccaaaaggtg gtatccgtat ggctgaaact actttgaaag aaaatggata cgaaccagac
     2821 ccagctgttc acgaaatctt cactaaatat gtaacaacag ttaacgacgg tattttccgt
     2881 gcctacactt caaatattcg tcgcgctcgt cacgcacaca ctgtaactgg tcttccagat
     2941 gcatactcac gcggacgtat catcggtgtt tacgcacgtc ttgctcttta cggtgcagac
     3001 tacttgatgc aagaaaaagt aaatgactgg aatgcaatca aagaaatcga tgaagaaaca
     3061 atccgtcttc gtgaagaagt aaaccttcaa taccaagcat tgcaacaagt tgttcgcctg
     3121 ggtgaccttt acggggttga tgttcgcaaa ccagcgatga acgtgaaaga agcaatccaa
     3181 tgggttaaca ttgctttcat ggctgtctgc cgtgtgatta acggtgctgc tacatctcta
     3241 ggtcgtgtac caatcgtatt ggacatcttt gcagaacgtg accttgctcg tggtacattt
     3301 actgaatcag aaatccaaga attcgttgat gatttcgtta tgaaacttcg tacagttaaa
     3361 tttgctcgta caaaagctta tgaccaattg tactcaggtg acccaacctt tatcacaact
     3421 tctatggctg gtatgggtaa cgacggtcgt caccgtgtta ctaagatgga ctaccgtttc
     3481 ttgaacactc ttgacaacat cggtaactca ccagaaccaa acttgacagt tctttggact
     3541 gacaaattgc catacaactt ccgtcgctac tgtatgcaca tgagccacaa acactcttct
     3601 atccaatacg aaggtgtaac aacaatggct aaagacggat atggtgaaat gagctgtatc
     3661 tcatgctgtg tgtctccact tgatccagaa aatgaagaac aacgccacaa catccagtac
     3721 ttcggtgctc gtgtaaacgt tcttaaagcc cttcttactg gtttgaatgg tggttacgac
     3781 gatgttcaca aagactacaa agtatttgat atcgaaccaa tccgtgacga agttcttgaa
     3841 tttgaatcag ttaaagcgaa ctttgaaaaa tctcttgact ggttgactga cacttacgta
     3901 gatgccttga acatcatcca ctacatgact gataggtaca actacgaagc tgttcaaatg
     3961 gccttcttgc caactaaaca acgtgccaac atgggattcg gtatctgtgg atttgctaac
     4021 actgttgata cattgtcagc tatcaaatac gctacagtta aaccaatccg tgacgaagat
     4081 ggctacatct acgattacga aacaatcggt gactacccac gctggggtga agatgaccca
     4141 cgttcaaacg aattggcaga atggttgatc gaagcttaca caactcgtct acgtagccac
     4201 aaactataca aagacgcaga agctacagta tcacttttga caatcacatc taacgttgct
     4261 tactctaaac aaactggtaa ctcaccagtt cacaaaggtg tatacctcaa cgaagatggt
     4321 tctgtgaact tgtctaaact tgaattcttc tcaccaggtg ctaacccatc taacaaagct
     4381 aaaggtggtt ggttgcaaaa cttgaactca ctttctagcc ttgactttag ttatgcagct
     4441 gacggtatct cattgactac acaagtatca cctcgcgctc ttggtaagac tcgtgatgaa
     4501 caagttgata acttggtaac aatccttgat ggttacttcg aaaacggtgg acaacacgtt
     4561 aacttgaacg ttatggactt gaacgatgtt tacgaaaaaa tcatgtcagg cgaagacgtt
     4621 atcgtacgta tctctggata ctgtgtaaac actaaatacc tcactccaga acaaaaaact
     4681 gaattgacac aacgtgtctt ccacgaagtt ctttcaatgg atgacgcctt ggatgcattg
     4741 agctaatcaa gttcttgaat aataaaaagg aaccctcggt caaacgactg agggttttgt
     4801 gcttgggata gtatgagcaa ttccttcggc gcaatatgca atgttttt
//
LOCUS       DAVHBD010000077         4524 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000077 DAVHBD010000000
VERSION     DAVHBD010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4524
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.077"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..379
                     /locus_tag="VVK04_002015"
     CDS             <1..379
                     /locus_tag="VVK04_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990620.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEETMTSDFFEAWFQK
                     FLLPTLNTPSVIIMDNVRFHRMGKLELLCEEFGRKLLPLPPYSPEYNPIEKTWAHIKK
                     HLKKVLPSCNTFYEALLSCSCFN"
     gene            complement(372..545)
                     /locus_tag="VVK04_002016"
     CDS             complement(372..545)
                     /locus_tag="VVK04_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU3990621.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFGGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(704..2311)
                     /locus_tag="VVK04_002017"
     CDS             complement(704..2311)
                     /locus_tag="VVK04_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU3990622.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2464..3948
                     /locus_tag="VVK04_002018"
     CDS             2464..3948
                     /locus_tag="VVK04_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU3990623.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPGGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNFKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4043..>4524
                     /locus_tag="VVK04_002019"
     CDS             4043..>4524
                     /locus_tag="VVK04_002019"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU3990624.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1321 a         1020 c          867 g         1316 t
ORIGIN      
        1 aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
       61 tggtgaatta atcgctccaa tgacttacga agagacgatg acgagcgact tttttgaagc
      121 ttggtttcag aagtttctct taccaacatt aaacacacca tcggttatta ttatggataa
      181 tgtaagattc catagaatgg gtaagttaga acttttatgc gaggagtttg ggcgtaaact
      241 tttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
      301 caaaaagcac ctcaaaaagg tattacccag ttgcaatacc ttttacgagg ctcttttgtc
      361 ctgttcttgt ttcaattgac tatgttatca gcgtaatagt ctaatagata gttaaatgta
      421 gttggatttc caccaaaggt tgatgagtaa gtttttgtat ctgaacctga ttggccgcaa
      481 gcagctaaaa gcaaagcaga tgcaaaagtc aggcctgcac taaggacacg cttctttatg
      541 ttcattttct ttctccttaa tagtgggaat ttgtaaagtt aattgaattt cgagaatgaa
      601 agtttataaa ccttggttat aaaaaacaaa ggatttctgt cttttataca gtcctccctt
      661 gtttttatac gatttcaatt ttaaattttt ctgcaaaaaa tatttatagt aattccacac
      721 agaaagcatc ccatggaact aagatttgtt tttcaaagac ttcttgagct agggtgtttt
      781 caatcaagac agatttgact tttccttcta ctgtcaagtc ttgctcttca ttagacaagt
      841 tagccacaac taggaagcga cggtcgccat ccttacgtat ataagcaaag accttatcag
      901 ccgtatcaag caattcaaag tcagctcgaa ttagccagct attctccttg cgaatttgga
      961 ccagtttctg ataggtatag aaaatagaat ctggatttgc cagcgcttct tggacgttga
     1021 tcatctcgta atttggatta accgccaacc aaggttgacc tgttgagaaa ccagcgtttt
     1081 tgctctcgtc ccattgcata ggggtacggg cattgtcacg tccaataaca cggatactgt
     1141 ccatgatttc ttcaatcgga acaccttttt caagagcctc acgcgcatag ttgagagatt
     1201 caatatcttc tacttgatct agtgtttcaa acggatagtt ggtcatccca atctcctcac
     1261 cttggtagat ataaggagtt cctctcataa gatgaagcaa gattgcaaag gctttggcag
     1321 atttttcgcg gtattcttgg tcatttcccc atattgagac aatacgaggg aggtcatggt
     1381 tgttccagaa gagggaattc cagccgtcct caactcctaa ctctgtctgc catttgttga
     1441 agatttcttt taacttagcg atattcagct ctttttgata gtgccattta ggctgacctt
     1501 cctgatactg aagaccgata tgttcaaact ggaagaccat agacaattct tgcccctttg
     1561 gatcagagta gagcttggca atctctggcg ttgctcccca agtctcccct actgtcaaga
     1621 gatccttatc tccaaaggtc gcctgattca tttccttgag atagggatgg agcataggac
     1681 cattattgac taccttctcg tcaggaattt tgccaatcat gtcaataaca tccatacgga
     1741 aaccaccaat acctttatca atccagaagt tcatcatctc ataaattttc tggcgaagtt
     1801 tttcattttc ccagttgaga tccggctgtt tcttgctgaa aaagtggaga tagtattgac
     1861 ctgacttttc atcgtattcc caagcagacc cactaaagat agaatctagg tcattgggtt
     1921 catcgcgcca gatatagtag tctcgctcag ggctgtcagt attttcacag gcttcgacaa
     1981 accaagcatg ctcatccgag gtatgattga ccaccaagtc catgatgata cggatatcac
     2041 gcttcttagc ttctgcaatc agctgatcca tgtcctccat ggttccaaaa atagccgcaa
     2101 tcgcttgata atcagcaata tcgtagccat tatcatccat agggctgtca taaacgggag
     2161 aaagccaaat cgctgtgatt cctaacttag ctagatagtc caacttactg gtaatacctg
     2221 gcaaatcacc aactccatct ccattactat ccataaaact ctttggatag acttgataga
     2281 ctacggcatt atgccaccat ttttcttgca tctgtttacc tcattatttt aataatctat
     2341 agtatatgat agcacttttt aaaattttgt gcaagcgttt gcttaatctt tttaatttct
     2401 tttttagctc cgtagtttcc taacttccaa ttttttatta taatagagtc cagaggtaaa
     2461 aaaatgaaaa aacaagcttt tagttctgaa cagtatttga atttacaacg cgaccatatt
     2521 ttggagcgca ttaaccaatt tgacggcaag ctctacttag agtttggcgg taaaatgtta
     2581 gaagatttcc acgctgctcg tgtccttcct ggttatgaac ctgacaacaa aatcaagctc
     2641 ttgcaagaat tgaaagagca ggttgaggtt gtgattgcca ttaatgctag caacattgaa
     2701 cattccaaag cacgtggcga cttaggcatt tcttatgacc aagaagttct tcgtttgatt
     2761 gacaaattca atgaattagg gatttttgtt ggttccgttg tcattacaca atacgctggc
     2821 caacccgctg cagatgcctt ccgcaaccaa cttgagaaaa acggaattga ttcttatctt
     2881 cattatccaa tcaaaggata tcctacggat atggatcaca tcatttcccc aggaggcatg
     2941 ggcaaaaacg actacatcaa aaccagtcgc aacttgattg tcgtaaccgc tcctggaccc
     3001 ggttctggaa aattggcaac gtgtatgtcc aatatgtacc acgaccaaat caatggcatc
     3061 aaatctggct acgctaaatt tgaaaccttc cctgtttgga atcttcccct tcatcatcca
     3121 gttaacttgg cttatgaagc tgccacagct gaccttgatg atgtcaacat gattgacccc
     3181 ttccatcttc aaacctatgg agaaaccact gtcaactaca accgtgatat cgaaatcttc
     3241 ccagtgctca aacgcatgtt ggaacgtatt ctcggaaaat caccatacgc ttcaccgaca
     3301 gatatgggtg tcaacatggt tggtttcgct attacagatg acgaggccgc tgtcgaagct
     3361 tctaaacaag aaatcatccg ccgttactat caaacagttc ttgacttcaa agctgaaaaa
     3421 gttggcgaag ctgccgtcaa gaaaattgag ttgctcatga acgacctcgg tatcacacct
     3481 gcagaccgta aggttgctgt cgttgcgcgc caaaaagcag aagaaactgg tggaccagcc
     3541 ctagcctttg aattgccaaa tggggaaatc gtcactggta agaactcaga actctttggt
     3601 cctacagccg ctgccttgat caacgccatc aaaaaatcag ctgacatcgc taaagaagta
     3661 aaactaatcg aacctgaagt tgttaagcca atccaaggtc ttaaaatcga tcatctcggt
     3721 agccgcaatc cacgccttca ttcaaatgaa atcctgattg cacttgctat cacagctaca
     3781 gaaaatcctg atgctgcccg cgctatggaa gaactcggca acttcaaagg aagcgaagcc
     3841 cactcaacca tcatcttgac tgatgaagac aagaatgtcc ttcgtaaact gggtatcaac
     3901 gtaacctttg acccatacta ccaatacgac cgcttatatc gtaagtaaag atttcaacct
     3961 ctccagcctc ggagaggttt tctctctgtc tcaggagcaa cctttatgat ataatgagag
     4021 aagaaaactg aaaggattta ccatgtcaaa agaagttatt gtcgaaagtt ttgaacttga
     4081 ccacaccatt gtcaaagcac cctatgttcg cttgattggg gaagaaacag gaccaaaagg
     4141 agacatcatc tccaattatg atattcgctt ggtgcaacca aacgaagact ctatccctac
     4201 cgccggcctt cacactatcg agcacctctt agccaaactc atccgtaccc gcattgacgg
     4261 catgattgac tgttcaccat ttggttgccg cacaggcttc cacatgatta tgtggggacg
     4321 tcacaccagt gctaaaatcg cagctgttat caaggattcg ctcaaggaaa tcgctgaaac
     4381 tactacttgg gaagatgtcc cagggacaac catcgaatct tgcggaaact acaaggacca
     4441 cagcctcttc tctgctaaag aatgggcaaa actcatcttg gaacaaggga tttcagatga
     4501 tgcctttgaa cgtcatgtga ttta
//
LOCUS       DAVHBD010000078         4303 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000078 DAVHBD010000000
VERSION     DAVHBD010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4303
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.078"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            31..1068
                     /locus_tag="VVK04_002020"
     CDS             31..1068
                     /locus_tag="VVK04_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU3990625.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            1070..1540
                     /locus_tag="VVK04_002021"
     CDS             1070..1540
                     /locus_tag="VVK04_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU3990626.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGHGLKGRGPVWWVPFEEMTAETCQVKPEEIKRLVECLSSEVDKLLEIKE"
     gene            1543..2259
                     /locus_tag="VVK04_002022"
     CDS             1543..2259
                     /locus_tag="VVK04_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU3990627.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGEAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AESGLSLEEYYGFEGGDYVD"
     gene            complement(2373..2453)
                     /locus_tag="VVK04_002023"
                     /pseudo
     CDS             complement(2373..2453)
                     /locus_tag="VVK04_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2579..3004
                     /gene="rplK"
                     /locus_tag="VVK04_002024"
     CDS             2579..3004
                     /gene="rplK"
                     /locus_tag="VVK04_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU3990628.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            3211..3900
                     /gene="rplA"
                     /locus_tag="VVK04_002025"
     CDS             3211..3900
                     /gene="rplA"
                     /locus_tag="VVK04_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU3990629.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT         1363 a          809 c          992 g         1139 t
ORIGIN      
        1 gttataatag gtagcgaaag aggtgaagaa atgaatcaaa cagtagaata tatcaaagaa
       61 ctgacagcca tcgcatcgcc aacgggcttt actcgtgaaa tttcgaatta tttagtcaag
      121 actctagaag gttttggtta ccagccagtt cgcacagcta agggtggtgt caatgtgacc
      181 atcaaaggtc aaaatgatga gcaacatcgc tatgtgactg ctcatgtgga tacgctgggt
      241 gctattgttc gtgctgtcaa accagatggt cgtcttaaat tggaccgtat cggtggtttt
      301 ccttggaaca tgattgaagg tgaaaactgt accgttcatg tggctagcac aggtcaaaag
      361 gtatcaggaa ccatcctcat ccaccaaact tcttgccatg tctacaagga tgcaggaact
      421 gcagagcgca cgcaggacaa tatggaagtg cgtttggatg taaaagtaag caatgaaaaa
      481 gaaactcgtg ctcttgggat tgaggtcggt gattttatca gcttcgatcc acgaactgtt
      541 gtgactgata caggttttat caagtctcgt catttggatg ataaggtcag cgcagcgatt
      601 ttgctcaacc tgcttcgtat ttataagaaa gagaagattg aattgccagt aacaactcat
      661 tttgcttttt cagtttttga agaagtagga catggtgcta attctaacat tcctgctcag
      721 gtagtagaat atctggctgt ggatatggga gctatgggag atgaccagca gacagatgag
      781 tacacagtat ctatctgtgt caaggatgct tcaggtcctt atcactatga cttccgtcaa
      841 cacttggttg ccttggcgaa agagcaagat attcctttta agctggacat ctatccattt
      901 tatggttcgg atgcttcagc ggctatgtct gcaggggcag aggtcaagca tgcccttctt
      961 ggagctggta ttgagtccag tcactcttat gagcgcaccc acatcgattc agtagtagcg
     1021 actgagcgta tggttgatgc ttatcttaag agcgaggcgg tatcatagaa tgtgcttaat
     1081 ctgtcagaga atcgaactca ttaaagctgg gcaaaatccc tactttgtca aagagttgga
     1141 aacaggctat cttgtgattg gagaccacca gtattttgca ggatatagtc tttttctagc
     1201 taaggaacac gttaccgaat tgcaccattt gaaaaaggaa acaagactcc gttttctcga
     1261 agaaatgagt ctagtccaag aggcagttgc caaggcattt gctgctgaga aaatgaatat
     1321 cgaactgcta ggaaatggcg atgcccatct tcattggcat ctgtttccta gacgaagagg
     1381 tgatatgaat ggtcacggtc tcaagggacg tgggccagtt tggtgggttc cctttgaaga
     1441 aatgacagca gaaacttgcc aagtaaaacc ggaagagatt aaaagattag tcgaatgttt
     1501 atcgtcagaa gtagataaac tattagaaat aaaggagtag aaatgaaaaa aagatacctt
     1561 gtcttgacag ctttgctagc cttgagtcta gcagcttgtt cacaagaaaa agcaaaaaat
     1621 gaagacggag aagctaagac agaacagaca gccaaagctg atggaacagt cggaagtaag
     1681 tctcaaggag ctgcccagaa gaaagcagaa gtggtcaata aaggtgatta ctacagcatt
     1741 caaggcaaat acgatgaaat catcgtagcc aacaaacact atccattgtc taaagactat
     1801 aatccagggg aaaatccaac agctaaggca gagttggtca aactcatcaa agcgatgcaa
     1861 gaggcaggtt tccccattag cgaccattac agtggcttta gaagttatga aactcagacc
     1921 aagctctatc aagattatgt caaccaagat gggaaggcag cagctgaccg ctactctgct
     1981 cgacctggtt atagcgaaca ccagacaggc ttggcctttg atgtgattgg gactgatggt
     2041 gatttggtga cagaagaaaa agcagcccaa tggcttttgg accatgcagc tgattatggc
     2101 tttgttgtcc gttatctcaa aggcaaggaa aaggaaacag gctatatggc tgaagaatgg
     2161 cacttgcgtt atgtaggaaa agaagctaaa gaaattgctg agagtggtct cagtttggaa
     2221 gaatactatg gctttgaagg cggagattac gtcgattaat actcttcgaa aatctcttca
     2281 aaccacgtca acgtcgcctt accgtgcgta tggttactga cttcgtcagt tctatccaca
     2341 atctcaaaac agtgttttga gctgacttcg tcagttttat ttgcaacctc aaagctatac
     2401 tttgagtagc ctgcggctag cttcctagtt tgctcattga ttttcattga gtataaaaaa
     2461 taaacttttc tcttgcaatt ctagataaat agtgtataat agatgggtat gtgaaaagca
     2521 tacttgtggg aggtaaaaat ctctaattac cgccaaaacc acaaaggagg atttaaaaat
     2581 ggctaaaaaa gtcgaaaaac ttgtaaaatt gcaaatccct gctggtaaag ctacaccagc
     2641 tccaccggtt ggacctgctc ttggtcaagc tggtatcaac atcatgggat tcacaaaaga
     2701 gttcaacgct cgtacagctg accaagctgg tatgatcatt ccagttgtta tctcagttta
     2761 cgaagataaa tcatttactt tcatcactaa aacaccacca gctgctgttc ttttgaaaaa
     2821 agctgcaggt gttgaaaaag gatcaggtac acctaacaaa actaaagttg ctacagttac
     2881 tcgtgcgcaa gtacaagaaa ttgcagaaac taagatgcca gatttgaacg cagcaaacgt
     2941 agagtctgca atgcgtatga tcgaaggtac tgctcgttct atgggattca ctgttgttga
     3001 ctaatcaata acacagtaga aaatctcaca gcagtctatt agttgctttt catactaggc
     3061 aagtgactga agcttgtact tgggtatagc aagggaactt aaggccgtag gaaaagaata
     3121 taatagactg ataacccgca agacttcatc atttcgagaa gtgacgtggg agatgaaaat
     3181 cgattgaacc acttacaagg agaatagaaa atggctaaaa aaagcaaaca acttcgtgct
     3241 gctcttgaga aaatcgacag cacaaaagca tacagcgtag aagaagctgt agcacttgca
     3301 aaagaaacta actttgcaaa atttgatgca actgtagaag ttgcttacaa cttgaacatc
     3361 gatgttaaaa aagctgacca acaaatccgt ggagcaatgg tattgccaaa cggtactggt
     3421 aaaacttcac gcgttcttgt tttcgcacgt ggtgcaaaag ctgaagaagc aaaagctgct
     3481 ggtgcagact ttgttggtga agatgacctt gttgctaaaa tcaacgacgg ttggttggac
     3541 ttcgacgtag ttatcgctac acctgatatg atggctcttg ttggacgtct tggacgtgtc
     3601 cttggaccac gtaacttgat gccaaaccct aaaactggta ctgtaacaat ggatgttgct
     3661 aaagcagttg aagagtctaa aggtggtaaa atcacttacc gtgctgaccg tgcaggtaac
     3721 gttcaagcaa tcatcggtaa agtatcattt gaagctgaaa aattggttga aaacttcaaa
     3781 gctttcaacg aaacaatcca aaaagcaaaa ccagctacag ctaaaggaac ttacgtaaca
     3841 aacttgacta tcacaactac tcaaggtgtt ggtatcaaag ttgacgtaaa ctcactttaa
     3901 tcagtagtta aactaatgta aaaaagttga agacgctatg tctcaacttt ttttgatgta
     3961 cgacgggcat gttgtatagt agattgaaac tagaatagta cacatctact tctaaaacat
     4021 tgttagaaat tgatttgact gtcctgatcg attcgtcctg ttcttatttc attttattat
     4081 atatttgagg tgtaagtcct cggtgggcac ctgctaccgg tgaacccaat agcgattccc
     4141 aagtctgact atcgtgaggt agcggattaa aacggtctgg ggatagaccg ttttaagtct
     4201 gacgctggaa ataagaatcg tcagaggaag agatagcgaa atcgtggctc tacgaacagg
     4261 aacgtgataa taaggcgtat atagcggata aggtatctgg ctg
//
LOCUS       DAVHBD010000079         3909 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000079 DAVHBD010000000
VERSION     DAVHBD010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.079"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            348..875
                     /locus_tag="VVK04_002026"
     CDS             348..875
                     /locus_tag="VVK04_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU3990630.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            952..1308
                     /gene="glnR"
                     /locus_tag="VVK04_002027"
     CDS             952..1308
                     /gene="glnR"
                     /locus_tag="VVK04_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU3990631.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            1345..2691
                     /gene="glnA"
                     /locus_tag="VVK04_002028"
     CDS             1345..2691
                     /gene="glnA"
                     /locus_tag="VVK04_002028"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU3990632.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2787..2906)
                     /locus_tag="VVK04_002029"
     CDS             complement(2787..2906)
                     /locus_tag="VVK04_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU3990633.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            3394..3909
                     /locus_tag="VVK04_002030"
                     /pseudo
     CDS             3394..3909
                     /locus_tag="VVK04_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         1219 a          668 c          765 g         1257 t
ORIGIN      
        1 gcgtcgtagt ccagtttggc gatgatttct ttgtgtgaat ccctattgac gacatctata
       61 atttggatat ttgtgtcttt gatatcgagt agttttgtga taaaatgtaa ttgtcccata
      121 tgaatctttc taatgagttg tttgatcgct tttcattata gatcttatgg gacttttttt
      181 ctacaataaa ataggctcca taatatctat agtggattta cccactacaa atattataga
      241 gcctgaaagt tcctcttttc ttttgcttaa aataaaaacg cttcctctca actattactc
      301 ataaaaatca ccgatttatg ataaaatgga aatagaaagt tgagattatg agttatttta
      361 aaaaatataa attcgataaa tcccagttca aacttggtat gcgaaccttt aaaacaggta
      421 ttgctgtttt tctagttctc ttgatttttg gcttttttgg ctggaaaggt cttcaaattg
      481 gtgctttgac agccgttttt agcctgaggg agagttttga tgagagtgtt cattttggga
      541 cttcgcgtat tctaggaaat agtatcggtg gactctatgc cttggtcttc ttcttattaa
      601 ataccttttt ccacgaagcc ttttgggtga ccttggtagt tgttccaatc tgcaccatgt
      661 taaccattat gacaaatgta gccatgaata acaaagcagg ggttattggt ggtgtagcag
      721 ctatgttaat cattacccta tcaattccaa gtggtgagac aatttcgtac gtgtttgtgc
      781 gtgtatcaga aacgtttatg ggagtttttg tcgcaattat cgtaaattac gatattgatc
      841 gtattcgtct ctttttagag aaaaaagaaa aataatgtta cattttataa cattatcaat
      901 tgacgtttgt ctttttttag actataatag acagaaagaa ggaaattgta aatgaaggaa
      961 aaagaatttc gccgaaatat ggctgttttt cctattggca gtgttatgaa gttgaccgat
     1021 ctatcggcgc gtcagattcg ttattatgaa gatcaagagt tgatcaagcc cgatcgaaac
     1081 gaaggaaatc gtcgcatgta ttccttgaat gacatggatc gtctgcttga aatcaaagat
     1141 tatatctctg aaggttataa tatcgctgcc attaagaaaa aatatgctga acgtgaagcg
     1201 aaatccaaga aagcggttag tcagactgaa gtacgtcgtg cacttcacaa tgaactcctc
     1261 caacaggggc gttttgcttc agtacagtca ccttttggtc gcggttaggc aaccgcaagt
     1321 agtcatagat taaggagaaa acttatgcca atcacagctg cagatattcg tcgtgaagtc
     1381 aaggaaaaaa atgttacctt tattcgtctt atgttctcag atattttggg aaccatgaaa
     1441 aacgtcgaaa ttcctgctac agatgaacag ttagataagg tcttgtcgaa caaggttatg
     1501 tttgatggat cttctattga aggttttgta cgtatcaatg agtcggatat gtacttgtac
     1561 ccggacttgg atacatggac agtcttccct tggggagatg aaaatggaag tgttgcaggt
     1621 ctgatctgtg atgtctatac aacagaaggt gaaccatttg cgggtgaccc tcgtggtaat
     1681 ttgaaacgag ctcttcgtca catggaagaa gttggattca aatccttcaa ccttggtcca
     1741 gagccagaat tcttcctatt taagttggat gaaaatgggg acccaacact tgaagtgaat
     1801 gacaagggtg gctactttga tttggcacct actgaccttg cggacaacac acgtcgtgag
     1861 attgtgaatg tcttgaccaa aatgggattt gaagtagaag cgagtcacca cgaggttgcg
     1921 gttggacagc atgagattga ctttaagtac gatgaagttc tccgtgcttg tgataagatt
     1981 caaatcttta agcttgttgt taaaaccatt gctcgcaaac acggacttta cgcaacattt
     2041 atggcgaagc caaaatttgg tattgctgga tcaggtatgc actgtaatat gtccttgttt
     2101 gatgcagaag gaaataacgc cttctttgat ccaaatgatc caaaaggaat gcagttgtca
     2161 gaaacagctt accatttcct aggcggtttg atcaagcatg cttacaacta tactgctatc
     2221 atgaacccaa cagttaactc atacaaacgt ttggttccag gttatgaagc gcctgtttac
     2281 attgcttggg ctggtcgtaa ccgttcgcca cttgtgcgcg tacctgcttc acgtggtatg
     2341 ggaactcgtc ttgagttgcg ttcagtggat ccaatggcga acccttacgt tgctatggct
     2401 gttcttttgg aagttggttt gtatggtatt gaaaataaaa tcgaagcacc agctcctatc
     2461 gaagaaaata tctacatcat gacagcagaa gagcgcaagg aagctggtat tacagacctt
     2521 ccatcaactc ttcacaacgc tttgaaagct ttgacagaag atgaagtggt taaagctgct
     2581 ctcggagatc acatctatac tagcttcctt gaagccaaac gaatcgaatg ggcaagttat
     2641 gcaaccttcg tttcacaatg ggaaattgat aattatttag acctttacta atactaatat
     2701 agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt ctaagccatc aaatacctat
     2761 aacccttaaa atagcgattt cggtcgctat ttatttttcg aaaaatcctc ttgactcttt
     2821 tgcgaattag atttatcatc agacgtgtag aagaaaatta aggagtcact atggaaaaat
     2881 tcaatttcaa aaacaatatc gggcaagaaa acaagttact tcaaatcgaa atctacaagt
     2941 ttactaactt ttgcaagctt caaaattaca catctgtaaa tattttttcg aaagatatat
     3001 ttgaagccat agtaaattga gactagaata gtacactaca tctgctaaaa atttctagaa
     3061 actaatttaa ctttcctaat cgatttgttt acatcttatt tcaatctact atattatctc
     3121 aataaatgat gatggcgact gttttgtttg tacttgtcga tttttgaatc ctgatcgagc
     3181 ggaagaatat ttctgccgag gttgccaagg ggaaaatcct gaagatattg aattttatga
     3241 tgaacaatta caggcagaaa aggtggaggt tttgaatatt cgattggaag taaaaaattg
     3301 aattatctac aatctcatca acaataaacc tatttcaacc ccattatcta taggcgtatt
     3361 tttacgcctt tttatatact tgaagcacat aagaaacatt atgggaagtt tgctgatgga
     3421 agtactcaag aaattgatgt tccttatgat attcctgata cttgggagtg ggtgaggata
     3481 aaatcaattt attggaattt tgggcaaaat aaaccagaga aatcctttag gtatatagat
     3541 acgtctagta ttgatagaaa aaagaacata atcaactaca aaaatctaca atatctttca
     3601 cctgaacaag cgccttcccg tgctagaaaa ttagtttcgc agaatagtgt cttattttca
     3661 acagttagac catatctaaa aaatattgct gtagttagag aacttaaaga gtatttgata
     3721 gctagtacag catttattgt tttggatact ttacttaacg aaacatattt gaaatattat
     3781 ttattatcag ataattttat caatcgtgtt aataataaat ctactggaac aagttatcct
     3841 gcaatcaatg attataattt taatctatta ttaattgctc tccccccact atccgaacaa
     3901 caacgaata
//
LOCUS       DAVHBD010000080         3566 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000080 DAVHBD010000000
VERSION     DAVHBD010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3566
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.080"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..463)
                     /locus_tag="VVK04_002031"
     CDS             complement(<1..463)
                     /locus_tag="VVK04_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990634.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCG"
     gene            complement(453..650)
                     /locus_tag="VVK04_002032"
     CDS             complement(453..650)
                     /locus_tag="VVK04_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990635.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(654..1448)
                     /locus_tag="VVK04_002033"
     CDS             complement(654..1448)
                     /locus_tag="VVK04_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990636.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(1856..2281)
                     /locus_tag="VVK04_002034"
     CDS             complement(1856..2281)
                     /locus_tag="VVK04_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990637.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEYMTTGDILIEAFKA"
     gene            complement(2410..2769)
                     /locus_tag="VVK04_002035"
     CDS             complement(2410..2769)
                     /locus_tag="VVK04_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990638.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGINHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(2815..3021)
                     /locus_tag="VVK04_002036"
     CDS             complement(2815..3021)
                     /locus_tag="VVK04_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990639.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3008..3169)
                     /locus_tag="VVK04_002037"
     CDS             complement(3008..3169)
                     /locus_tag="VVK04_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU3990640.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
BASE COUNT         1148 a          715 c          444 g         1259 t
ORIGIN      
        1 aaccacaatt actcaatacc gaatacccct gaatggtttc tttttcatgc accaatatat
       61 tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca aaatgtaagg
      121 gaatttctcg accgtccttc tttaatggat attctggtaa gatactaaat agttcaatca
      181 tagaaggaaa ctcaggatta gttgttgtaa atcgaaaaag ctgcgctttc tcatctttct
      241 gacttccttg atactctccc aattctaaaa aatgattcaa ggtagtataa aattccttat
      301 tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt ttaaatcctt
      361 gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag ttctgaaaat
      421 ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc tcccagatac
      481 tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc atcatcatct
      541 tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt atttttaaaa
      601 tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat ctttcatttt
      661 aaaacatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca tatgacatag
      721 ctaatatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata agcaccacca
      781 tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa taaaatccgt
      841 tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt ctttgacacc
      901 gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa agtcctcaaa
      961 cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc aacatctact
     1021 actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct aggtgttaat
     1081 tccttaggga cttcagtatc attcgcattg agtactagtc ccaatggagg gaagaagagg
     1141 tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt ttcactgtct
     1201 gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat agtgcgagcc
     1261 tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa aaatgattcc
     1321 ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg taaagtcaaa
     1381 gtcagttcct caatactgac atcaacataa aaggattgaa aaattgacat tatctttttg
     1441 acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc ggtataataa
     1501 aatataagtt ttttgataaa ataaccaaaa actactccct atcccctctc acattaccct
     1561 acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac ttttctctca
     1621 tccactatgc aggacttact atttcacttc tactcctata ggctcaattt gacacttttc
     1681 tttttcgaat tgctcatatg cctcctgaat agtgagttcg atttatccaa atttattttt
     1741 gtctattttg atgaatactt ccacgaagat agtctgaaaa tgaatttgca ccaattttcc
     1801 ttctcttttt aagcatatta ttccagatat gattgccctc ttattcagta ataaattacg
     1861 ctttaaacgc ttcaatcagt atatctcctg ttgtcatata ttctaaagaa aattcttcta
     1921 catatgattt aacatctctt aggttattac ttcctaatat cccattatgc tttttcgcta
     1981 aggaaataga tgccccttct cccttaccaa taatcttgtt actatcatga tttcttgtta
     2041 aatctctata taatgcgtat tcttcagttc caatgtctat gctcacaatc tcagctgaac
     2101 ccttagctac caactgatct atcctagatt ttaaatgggg aattgtaggt atattgattt
     2161 catcatacac ctcttgtgga ataacaattt tacccaaata gagcttttct aaaagatgtt
     2221 cagtgccaac ccataaaaat actgaaatac aatctgcatc aataaataca cgactagtca
     2281 aacgacaact cccccctctt catctagccc atatacaata tcatatctga aagcatctag
     2341 taacagttcc tcatacttcc cttgcgaaat tctgttattt tctaaaagtt gttcagttga
     2401 attaatatat tatcctaatg ccatttcttt tttactttct gacaaaggac gatataaact
     2461 tgtatcatag cctaatcttg aagctgtctc tataacacta atatccatat ttttaatttc
     2521 ttctgcatca aggtatccat cattcctcaa tctatataac atagctttat gattgatacc
     2581 ataaaactga cccaatttta taatatcttc tacttcaaga tgagttctat tggcattttc
     2641 tctgatttcc tcaaccatcc tatacagtga agatgggaaa attaaaaaat aagaagcaaa
     2701 ctgatccgct tttctttcag tttcatctcc ttcaccaatc aagataagac tgactgaact
     2761 cttcttcacc tcatcataat aaagatgata cagtccatgt gctaaagaaa atctttacct
     2821 tcctaatggc atgtctgaat tgactgcaat gagactgaac tgagttcctt tataacagac
     2881 tccgctaata ttctttccga gtccataaaa taccagcgtc aaattttcta tcttttgtac
     2941 caatttaaaa atatctatcg gcgattcacc atcagctccc aacttttttc taagatttga
     3001 agctttatta cttaaatcca ttcgtgatat tcctttcacc tttttccatt ttggcaatca
     3061 tgctttgatt caaagacaaa tactcagcaa tcttatcttg agtaagattt gaagatattc
     3121 taagttcttt tattcttttt ccaacatcac atacatttat cacatacatt tatcatattc
     3181 atacacctct cataaaaaga atagcacact cttgtcataa ttttttaaat aaaaaaatta
     3241 tgacaaaaca aggaagcaat ttattgatgc tgcttaaaaa tctaaaattg atgagttcct
     3301 atcaaaaatc gtatcttcaa cctcaaaaca gtacttaaag ctatccgact cggtttacat
     3361 tgtcaaattt agattttatt tgagcataac tttctagttt gctttctgat ttttgtttaa
     3421 tatagtagca aacattgaag gaaatatctc cacaagaaaa cgcatactat taagcttttt
     3481 caagacctaa taatatgcgc tgttctgatt tgaaagacat tccattatta ttttactgta
     3541 atcaagccat ctggctctac tgtgaa
//
LOCUS       DAVHBD010000081         3377 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000081 DAVHBD010000000
VERSION     DAVHBD010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.081"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..244
                     /locus_tag="VVK04_002038"
     CDS             <1..244
                     /locus_tag="VVK04_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEU3990641.1"
                     /translation="ENSHLIYADYFEMKLQKLLKDDTKVFEKSTFKFVEGYKIYLTES
                     KESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(599..1132)
                     /locus_tag="VVK04_002039"
     CDS             complement(599..1132)
                     /locus_tag="VVK04_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU3990642.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1221..1997)
                     /gene="recX"
                     /locus_tag="VVK04_002040"
     CDS             complement(1221..1997)
                     /gene="recX"
                     /locus_tag="VVK04_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU3990643.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2035..>3377
                     /gene="rlmD"
                     /locus_tag="VVK04_002041"
     CDS             2035..>3377
                     /gene="rlmD"
                     /locus_tag="VVK04_002041"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU3990644.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLDYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVSKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKL"
BASE COUNT         1101 a          576 c          589 g         1111 t
ORIGIN      
        1 cgaaaattca catctaatat atgcagacta ttttgaaatg aaattacaaa aattattaaa
       61 agatgacaca aaagtttttg aaaaatctac attcaaattt gtagaaggat ataaaatata
      121 cctgacagaa tctaaagaat ctggaattaa acaaatggac aatgtcataa aatattttga
      181 gtttattgaa tctaaaagta ttgctttata ttttcaaaaa cgattaaatg agctgataga
      241 ttaaatatca ttttctctgt taagatattg tttttaaaat attgtactaa atgattgatg
      301 ctatgtggaa atacaaaaaa atgtttttga tacgaagttg acctgtattt tttatactaa
      361 tcattttcgt attttttgta ttaaacgata taagtttgtt gtaaacttac aaggaataaa
      421 gacattaaaa aataacagta tatctatttg ttttatatat tttacgaatt ttgcataaat
      481 ctctttctag taatgtgttg taactctgct ataatagatt tattcctttt tgtgtttaca
      541 caatttattt tatactacca aaaaaaggtc aggattttgt tcctgacctt tgacaacttt
      601 accgattctt tagttctaca tagcgcttgt accaaatgtt tacataggct tctgagaaag
      661 gaccacgtcc attgttaatc caatcaacaa gaattttgac atgttctttt aaaatatagt
      721 ccaagtcatc agaataattc attttgcgtt tgtgacgctc gtactcttca acgtccaaga
      781 gacgtttttc cccatctgta aaaattttaa catccaaatc gtaatcaata tacttcagtg
      841 cttcttcatc cagatagtag gggctagcca tattgcaata gtaagaagtt ccattatcac
      901 gaatcatggc aatgatatta aaccaatatt tcttgtgaaa gtaaacaata gccggttctc
      961 gagtgaccca acgacgacca tcactttcgg taacaagtgt atgatcgttg acaccaataa
     1021 tggcgttttc tgttgttttt agtaccatgg tgtcccgcca agttcggtgg agactcccat
     1081 catgcttata actttgaatt gtaataaagt cgccttcttt tggaagcttc ataactaacc
     1141 aactttctac aatttataag tttatcattt actattgtac cataaaatta cctaaaatct
     1201 gtgaatttca cttggaaata ttaaagatat tctctaagag cgcttgctat atccgaaaaa
     1261 tcgtagccct ttcgtgctaa aacttgagtt aaacgctgct tcagttcgta tccttcatac
     1321 tttcgagcat acttagtata ttgcttatca agttccttga agatgagttc ttgagtcgtt
     1381 tcttggtcaa cttggctatc taagtcgtca aaggcaattt tagcatcaga ataagagaag
     1441 cccttgttag tcaagttctg gataatctta tcttgcaggg cacgagctgg aagttttccc
     1501 tcatattttt tcaatagttt attagctaca cgttgagcaa cttcagaaaa atcaaattct
     1561 ttcaagttct cttctatagt agattttgaa atcccttttt gagctagttt ctgagtcagc
     1621 acataaggac ccttgtctcc tgaaagttga ttggtattga tgatagcata agcgtactga
     1681 ccatcattaa tccacttatc ttctttaaga ttagcaataa cttgagaaac gatgttttca
     1741 tcaatatcgt attttttcag atattctctg acttcttttt cagtgcgtgc tttaaaggat
     1801 aagtggtaga gggccagatt cttaccataa gaaaattgag caaagtcttg aatctctttc
     1861 aattcctctt cgcttatcac cttatctctc gataacataa aacgaacaat tgtatcttcg
     1921 gtgatatagc atttgtcgcc attatcaagc tccatcagat agagtctttt tttcttttca
     1981 agttttgtga ttttcatagc tctattataa ctcaaaatgt gataagatag gggtatgaat
     2041 ctgaaagtga aacaaaaaat accattaaaa atcaaacgca tgggaattaa tggtgaggga
     2101 atcggctttt accaaaaaac attagtcttt gtacctggag ctctcaaagg cgaagatatc
     2161 tattgtcaga ttacttctat tagacgcaac tttgttgaag caaaattact gaaggtcaac
     2221 aagaagtcta aatttcgaat tgtgccatct tgtactattt ataatgaatg cggaggctgc
     2281 caaatcatgc acctgcatta tgataagcag ctggagttca agacggactt acttcatcaa
     2341 gcgctgaaaa aatttgctcc tgcaggatat gaaaattatg aaattcgtcc aactattgga
     2401 atgcaggaac caaaatatta cagagctaag ttacaatttc agactcgaaa atttaaaaat
     2461 caggtcaagg cgggcttata tgcacaaaac tctcactatt tagtagagtt gaaagactgc
     2521 ctggtacaag ataaggaaac ccaagtgatt gctaatcgct tagcagaatt acttacttat
     2581 caccagattc caatcacgga tgagagaaaa gttctaggtg tccgtactat tatggtccga
     2641 cgcgcgagaa agaccggaca ggttcagatt attattgtta caaaccgcca gcttaattta
     2701 acccaactgg taaaagagtt ggttaaagat tttccagaag ttgtgacagt agctgttaat
     2761 acaaatacag ctaaaaccag tgagatatat ggtgaaaaga cagagattat ctggggacaa
     2821 gagagtattc aagaaggtgt actcgattat gaattttcac tatcccctcg agctttctat
     2881 caactaaatc ctgaacaaac agaagtcctt tatagcgagg cagtaaaagc gctggatgtt
     2941 agtaaagaag accatttgat tgacgcttat tgtggagttg gaacaattgg ttttgccttt
     3001 gcaaagaaag taaaaacact cagaggtatg gatattattc cagaagctat tgaagatgcc
     3061 aagcgaaatg ctaaaagaat gggatttgac aatactcatt atgaagctgg aacggcagaa
     3121 gagattattc ctcgttggta caaggaaggc taccgagcag atgctttgat tgttgaccca
     3181 ccacgtacag gtctggatga taagttatta gatactattc ttacttatgt accagaaaaa
     3241 atggtctata tttcttgtaa tgtttcgacc ttggctcgtg atttggtacg cttagtagaa
     3301 gtctatgatc ttcattatat ccagtcggtc gatatgttcc cacatacagc tcgaactgaa
     3361 gctgttgtaa aattaat
//
LOCUS       DAVHBD010000082         3133 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000082 DAVHBD010000000
VERSION     DAVHBD010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.082"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            184..1161
                     /locus_tag="VVK04_002042"
     CDS             184..1161
                     /locus_tag="VVK04_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990645.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRLKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            1538..1912
                     /locus_tag="VVK04_002043"
     CDS             1538..1912
                     /locus_tag="VVK04_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU3990646.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            2120..3022
                     /locus_tag="VVK04_002044"
     CDS             2120..3022
                     /locus_tag="VVK04_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990647.1"
                     /translation="MIRKPIIFLLMLPIWGLWIELHLLVSNLQLNLEIPFDFVVSTSL
                     TFFVLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
BASE COUNT         1059 a          406 c          545 g         1123 t
ORIGIN      
        1 ttatttatac tgttgcagta ggcattgtct aggataaata agctatcttg atgggggaga
       61 ttggaataat tttagtagaa acattaaagg attatggaca agtagcgcag gattaagtga
      121 tgcaatgtgc taagttggct tggtgttagc agtagtatta tttaacaatg gaaagtagac
      181 taaatgaaaa ataagcgtta tttttttgac acaattttaa tgattttact gcttataagc
      241 acgatatttt gtgtcagccc agtatttata aaattggaca tcttaggaac cccctctcat
      301 gccatcttaa cctttgtatt ggcgataccg ttattctata ttttgtctca atgcttacat
      361 actttgctat tactagtttc ctcaatcttt tgtaaattaa gaccaattta tttttatttt
      421 atatttgtga tcattatagg agctaggaaa tactatcgaa ttctctttca ccaactaatg
      481 ggatttagtc caggaatagc agtgttttat aaggagagtc aaacaactaa gaatctgttt
      541 aaattttact acttcttgta ctttacaaca ctaatttcat actatttttt ctttactttt
      601 gtgtatgaca aaccgttgct tttgcctctt atttcatttt ctattatcat agcattagta
      661 caaaaacttt atagaattga gaatcaacaa ttatttctgt taaaatcaaa ggtactaaca
      721 atactggaat ctaagaagaa ttgtgagttt aatcttcagg attatcatga aatttggaaa
      781 ttgcaatcaa aatctgagtt gccatgcgtg gctttatctt atatcagttt gatcaagcca
      841 tatctttcag agagcgtgcg tgaacaaatt gatttattag aagttaagcg attaaaaaaa
      901 ataaatcatc caatatcact ttatggtatg ttggatgtta taaaattaaa tctatattta
      961 cggcactata atgaaaaaaa taaatatgaa tcaatgttaa agaaaatttt agaggtaaga
     1021 ccagactttg ttttaatcga gcagaatatt gatgatagtt taaatagctc gcaaccatta
     1081 tctttatctt tagctatttc agaaatccaa cttttgcttg aagtgtatat ggggatcaaa
     1141 catgtttcaa ttaggagata aaactagaat aacatttgct attatagggg caagttgcat
     1201 attagtcagt atgtatctta tacctctcat taacacggat aataaatttt gggaaatact
     1261 tttatttata ataggtgtat tgctaattgg aattgcgtta ctaagtcaaa aaaaataaat
     1321 tttgaaatag tattagtgag ttcgcaatca tttattgcta gtggtttaga actgttaagt
     1381 ttcaagcaat aattggtttt aaaccttagg taacctataa aaacaaataa ggtagagaaa
     1441 ggatatctta tctaggtaac taagtgctat aaacaaagtc aacgatcact tgttaggaaa
     1501 ctatcctaac tatgcttaat aaaaaaggag aaaataaatg gaactcgtat taccaaataa
     1561 ttatgttgct cttgagcaag aagagatgat gtatcttgat gggggatttt ctattccgag
     1621 atggcctgtt gcaacagcca ttaatatagc ttttaatggt gttttaggtg gaggagcaat
     1681 cagtctagtt agaaattata ttcgtaatta tggtttgcgg cgagttacaa gcgcaattgc
     1741 tggagcagct gcaagatatg ttggggtacg agttgcaaat agagtggcag gatttgcact
     1801 gtctgctatt aatggatttg cagcttggat gtcaattggc aatgctatta caacaatctg
     1861 ggccaataat gatgtaaata ggagagaccc aaatttaaac gccttgtggt aactagatat
     1921 gggtattaaa atggaaaaaa tttttgttat tatttttttt gtatgtctat ttatatcatc
     1981 cataactttt ttagcctatg attttgttag cgaagaaata aaaaagttga ttatttggat
     2041 gaatgtcgtt tttttgattt taatcatagc aatgataatt tatccaaaat taagaaaatg
     2101 ataaggacac tgtaaaatta tgatacgtaa accaatcatt tttttattaa tgctccctat
     2161 ttggggcttg tggatagagt tgcatttgtt agtgagtaac ttgcaattga atctagaaat
     2221 tccctttgat tttgtggtta gtacgagtct tacttttttt gttttgatat tatcaaaaat
     2281 agttttagac atactatacg cattgaaaga tttgtacaag aaagaagctc ttattacgat
     2341 ttttcctttt atttttatag gcaggaagaa agtaaatgtg aggttctcgc cctatttttc
     2401 attccatcgt aaaagtttgt cgcctgatga tttaagatct aggattatat ggagttttat
     2461 tcttgaaatt gctattatcc tagtatttat tttaaaaatt ccttttgcaa tcatcatgct
     2521 tactacaata tttttctgga ctataatgga tatcaatcat ctcgttttta ataagacgga
     2581 atttcttttc aatcaaaata aatgggaaaa agaagattcg tttgaaagtg atttgacaaa
     2641 tacgttaaag gataaaatac aaaaatcaga tctcagttat tctgacttaa tgtctcttca
     2701 gctgtatgat gcgatgaatc aatctacctt tttaacggat agtgaactct ttgaggatat
     2761 tctgagtaaa attgaagatt ctcataacac ccttctgtgt acaggtcttg tcgagttact
     2821 gctgtatgag atttctatta gtaacaataa caactggtcc aacaaggttg ataaaattag
     2881 gatacacctc atcagaatca atcaattaga ttttttctat tatacaagtt ggttaaggca
     2941 aaattttgat ttctgtatga atagagagta tcataaaatg aaatctcgga aattattact
     3001 gagtaataaa aagatagttt aagttcgtcc tatttgtaaa acaaatgaaa caatttcaac
     3061 taaggaggag aaaacaaatg gaacttgtat taccaaataa ttatgttgtg attgatgaag
     3121 aagaaatgat gta
//
LOCUS       DAVHBD010000083         3107 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000083 DAVHBD010000000
VERSION     DAVHBD010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.083"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            783..1022
                     /locus_tag="VVK04_002045"
     CDS             783..1022
                     /locus_tag="VVK04_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990648.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            1570..>3107
                     /locus_tag="VVK04_002046"
     CDS             1570..>3107
                     /locus_tag="VVK04_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEU3990649.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEDAPVANQSQAEK
                     DYDVAMKNAEDAKKAVKDAQKDLDDAKAAQKEYEDGQKKTEEKGAREEETAKKVNDAA
                     LAQQKAYAEYIKANQEQGRDRKEKLAEAQRKIDEATKKLEEAKKEFQTVRQTIVIPER
                     EKLAETKKKAEEAEQKEPELTKKLEEAKVKLEEAEKKATEAKQKVDAEHAEEVVPQAK
                     IAELENEVQKLEKDLKEIDESDSEDYVKEGLRAPLQSELDAKQAKLSKLEELSDKIDE
                     LDAEIAKLEKNVEDFKNSNGEQAEQYLAAAEEDLVAKKAELEKTEADLKKAVNKPEKP
                     AEEPENPAPAPKPAPQPEKPEKPADQPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPP
                     KAEKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAM
                     ATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWLQYNDSWYYLNANG
                     AMATG"
BASE COUNT         1161 a          472 c          639 g          835 t
ORIGIN      
        1 agcaaaggaa tacgaattat ttaaaaatag caagtaatag aaacataggt taaatcttag
       61 aacggcttaa aatcagatat gataaaggga aatagtctta tctaggtaac taagtgctac
      121 aaacacagtc gaggatcact tgttaggatt acattttaat catgcttaat aagaatggag
      181 aattcctatg gggattgtat tactctgaag tttcgaatac cttagttctc gtgattttga
      241 gctgttctag ctttagaatc cttcagaatg taaaatttta agcagtcaaa gacttagaat
      301 agcctggaaa catttatttt atagcaattc taggcttaga attgctcata tatatgtatt
      361 tgagctgctc gatagttagg acagctctat tctgagaaat ctgagctatc aatgcttcag
      421 aatagtattt cgcaaatggt ttttattgaa gaggtgattg ttttatgata gtctaaaata
      481 aaactgattt aatggagtaa atggagaatc gtcacatgaa acattttttt gcaggaattg
      541 gtgagataaa acttgttggc tacttattgt atatatgtgt aggactagcc cctctttttc
      601 atatatatgt cataggttcg gaactgagtt ttgtgaaaat agtgttatct attttgggaa
      661 ttatatttgt aagtatgtta actattgctc gaatttatag gacttttttc tataaagaat
      721 agtttggact tgaactgtat ctaaaaacag aggttggtcg attatcagcc tctttcttgt
      781 cgttgaaatt acttgattgt attttggact atcaagaaag attcaatgga aaaacatgtc
      841 aagtatcaac gaattataag tatttagaga ttttcaaagt gaatttttgc ttgactgatt
      901 tacatcattt atttggctta cacaaaatca cacgagatta tgctagtcaa acaaaacctg
      961 ctattcaagc tggtgttttt attttagaag attttagaaa tatcctatgt acaatgatgt
     1021 aatcgaaagg atatctttat gtgagtttat cggcgatatt ttctattcta aaataacaag
     1081 ttgttgtatc gtactaagga tttatctaaa aatactatga aattggacgt catatttttt
     1141 gaggataaaa ataaaagatc cgcagtttta ggtttacgaa gagacaaaag cggagtattt
     1201 aaaccagtta ctctacattt tacaagcgct aagaaatatg ctaaagttcg taaaacagat
     1261 gtgaaagaaa tgaaatggct ataaagattg tccgcaggct taagcttgcg ttttttgttg
     1321 tttaacgaaa ttaaaaaaca agctctctca tcggaaatgt ttttatagga atgaaggaag
     1381 atgatgctat gtttaaaaag agaatcgaaa agggcaaaag tagtgtcttt atctttttgg
     1441 agcagaagct tatgatatag aaatttgtaa taaaaatgta atataaaaca tttgacaaat
     1501 atttacgggg ggagtatact taatataagt atagtctaaa aatgactatc agaaaagagg
     1561 taaatttaga tgaataagaa aaaaatgatt ttaacaagtc tagccagcgt cgctatctta
     1621 ggggctggtt ttgttgcgtc tcagcctact tttgtaagag cagaagacgc tcctgtagct
     1681 aaccagtctc aagctgagaa agactatgat gtagcaatga aaaatgctga ggatgcgaaa
     1741 aaagcagtaa aagatgctca aaaagattta gatgacgcaa aagctgctca gaaagagtat
     1801 gaagatggtc agaagaaaac tgaggagaaa ggcgcgcgag aagaagaaac tgctaagaag
     1861 gtaaacgatg ctgctttagc gcaacaaaaa gcatatgcag aatatataaa agctaatcag
     1921 gaacaaggta gggaccgtaa ggaaaaatta gcagaggcgc aaagaaaaat agatgaagcg
     1981 actaaaaaac tagaagaagc taagaaggag tttcaaactg taagacaaac aatagtaatt
     2041 cctgagcgag agaagttggc tgagactaag aaaaaagcag aagaggctga acaaaaagaa
     2101 ccagaactta ctaaaaaact agaagaagct aaagtaaaat tagaagaagc tgagaaaaaa
     2161 gctactgaag ccaaacaaaa agtggatgca gaacatgctg aagaagtcgt tcctcaagct
     2221 aaaatcgctg agttggaaaa tgaagttcag aaactagaaa aagatctcaa agagattgat
     2281 gaatctgact cagaagatta tgttaaagaa ggtctccgtg ctcctcttca atctgaattg
     2341 gatgccaaac aagctaaact atcaaaactt gaagagttga gtgataagat tgatgagtta
     2401 gacgctgaaa ttgcaaaact tgaaaaaaat gtagaagatt tcaaaaactc aaacggtgag
     2461 caagctgaac aataccttgc tgcagctgaa gaagacttag ttgctaaaaa agctgaatta
     2521 gaaaaaactg aagctgacct taagaaagca gttaataagc cagaaaaacc agctgaagag
     2581 cctgagaatc cagctcctgc accaaaacca gcgcctcaac cagaaaaacc agagaagcca
     2641 gctgatcaac caaaaccaga aaaaacagat gatcaacaag ctgaagaaga ctatgctcgt
     2701 agatcagaag aagaatataa ccgcttgccc caacagcaac cgccaaaagc agaaaaacca
     2761 gctccagcac caaaaccaga gcaaccagtt cctgcaccaa aaacaggttg gaaacaagaa
     2821 aacggtatgt ggtacttcta caatactgat ggttcaatgg ctacaggttg gctccaaaac
     2881 aacggttcat ggtattacct caacagcaat ggcgctatgg ctacaggttg gctccaatac
     2941 aatggttcat ggtattacct aaacgctaac ggcgctatgg ctacaggttg ggctaaagtc
     3001 aacggttcat ggtactacct caacgctaat ggtgctatgg ctacaggttg gctccaatac
     3061 aacgattcat ggtattacct aaacgctaac ggcgctatgg cgacagg
//
LOCUS       DAVHBD010000084         2535 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000084 DAVHBD010000000
VERSION     DAVHBD010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.084"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..559
                     /locus_tag="VVK04_002047"
     CDS             <1..559
                     /locus_tag="VVK04_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU3990650.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VVK04_002048"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VVK04_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU3990651.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2032
                     /locus_tag="VVK04_002049"
     CDS             1424..2032
                     /locus_tag="VVK04_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU3990652.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPTYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNQEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(1980..>2535)
                     /locus_tag="VVK04_002050"
     CDS             complement(1980..>2535)
                     /locus_tag="VVK04_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU3990653.1"
                     /translation="NIPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIK
                     PLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGG
                     FIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLA
                     PFEEQELITQKVEKLFEKVNQLWK"
BASE COUNT          891 a          378 c          424 g          842 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaacca tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaataaa gacgaaacaa cctcttatcc
     1501 tacatatgaa atcccagaag catggagata tattaaattt gctagcctag ttaacttcag
     1561 aataggaaaa actcctccac gcagtgaagc tactttttgg ggaactgaaa taccttgggt
     1621 atctatatca gatatgccta tatctggtta tgtaactaat acgagagaat ctatttctaa
     1681 attagcatta aaatcaaaga aaatagacat ttcacctaaa ggaactttat taatgagttt
     1741 taaattatct attggaaaag ttgccatatt ggatattcct gccactcata atgaagccat
     1801 tatatcgata ttcccctatg ctaataaaga aaatattatc agagattact taatgatatt
     1861 tttgccactt atctctactt taggtgattc aaaagatgct atcaaaggga aaacattaaa
     1921 tagtaccagt atctccgaat tattaatccc tatttctaat caagaagaga tgaaaagaat
     1981 catttccaaa gttgatttac tttttcaaaa agtttctcaa ctttttgagt aataagttcc
     2041 tgttcctcaa aaggagctaa cggaattaat agctcgctta gtgtagtttt aggaatatta
     2101 tataaagctt gacctgatag tttagttatt gctttcaatt gtttataaaa taacggagag
     2161 gacaagttaa ataatagaaa ttttgaaata atctctgaac tttcgaatgg tgttaattgg
     2221 aaaataaatc caccagccac aacaccatca tagtctttat cgattcttgc aaattttcca
     2281 atatgttcta aagaggttga tacaggtgtt attagctgat tatgttttaa ataaacttgc
     2341 tcagaggaga tgaattgtgt atcaatgtag taatcgttat ccaacagaga aaattctaaa
     2401 ggcttaatat taccaccacg tataattcta acacctttat tattaatgct taaatcgccc
     2461 ttcttgtaag aaagacctgt attcattgaa aaaatatctt ttatttttat aacaacccaa
     2521 ttcataggta tattc
//
LOCUS       DAVHBD010000085         2462 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000085 DAVHBD010000000
VERSION     DAVHBD010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.085"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(120..1178)
                     /locus_tag="VVK04_002051"
     CDS             complement(120..1178)
                     /locus_tag="VVK04_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990654.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSKVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSLIKG"
     gene            complement(2060..2272)
                     /locus_tag="VVK04_002052"
     CDS             complement(2060..2272)
                     /locus_tag="VVK04_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990655.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
BASE COUNT          931 a          424 c          283 g          824 t
ORIGIN      
        1 atcttttctg gcaatcatat gagtagccta atgatatttc tagttactca aaaatatcta
       61 gctatactag agttatttct aatccctagg acacttgtta atccaaatgt aacaaatttt
      121 caccccttaa taagactctt tctggaaaaa atataaggtc tatctttata aaaaaatcta
      181 tcatattggg atggcacgca tctggaattt aaacaagcta taaattcatt tataactact
      241 atttgtttag aggcaacagc atcttgtata ccgccctcga aagaaccatc ttgtaattcc
      301 gaaatatttt tgtttaaata ttgttttgac aaatctctta atgcttcatt atcgtaaatg
      361 attcccaaaa atccaacctt atatagtaaa taatttaaac ttacaaagta attgaatccc
      421 atagtatatt tttctttata aagcaaaggt aaaactttat aaaaaatatc taagtcaacc
      481 ttactctgat tctgaagcaa gtaggagtca agcaaatttt caaaaatagc taacaatatg
      541 attggtgtaa ggtttttgta ttcacatgtc aagtattccg agtatcgtgc agatgatatt
      601 tcttttacat aactttttga aagcaagatt ttttcaaatt catcatctat tattaatctt
      661 ctatttccaa tccaaacggt attaccaccc aaataagatt gtgcaaatag caatatgtaa
      721 gaaaacatga acgtaaatac tgaaagaggt agaattctat gcgtaaaaaa atagacgata
      781 atggtagcca ggagtaaagc tatctctcgt gacaatcgaa ttcttttcag catctttttt
      841 aacagtccgt aaggttgtcc ttggcaatat tcttgaacta aattaatcgg aatgacatct
      901 ctcaccattt ctggaaagta gagtaagttt ataggttgaa atctccagct cccatcataa
      961 gtaaatggat atagaaccaa atacttaaaa gatttttttc ttataaactt aattatcaca
     1021 atatgaatga ctgttgcaat gaagtatatt aaatataaaa gtaaaaccgc catcaatata
     1081 cttacaaaaa tccccttgga ctcaatcaat ggaaaataaa atattgcaac tagaagcgaa
     1141 taaagtcccg ctaataaata tttctgatca tctttcattc aaaacaccat attatttact
     1201 aagaatacat caatacaata gagcaactct gtaagtcaat atttgataaa gcaaagcttt
     1261 aaccccttcc ccagacgtta gcttttcttc aacccactac agttgacaag gagcccaaat
     1321 tattgataaa aactttagtc atcatcgtct ctataaaaat attttctata cactcttgat
     1381 aataccaaaa ttaatgccaa tatcatacca agagctataa taatagaatt tattagattt
     1441 attttagtat atccaatcac tagtccaata attggactag cagacatgct tagatataat
     1501 aaaaataaca aaaaatgaat ttcaccaatt cctgcaaaaa aatgtttcat agctatagtt
     1561 ttacgcccat aaatacccat caaatttacc gtctacgata tctaaaccat atgcaatggc
     1621 tcctcctaat gagaagactt cagcaacagt agccgcaata ttaagagcat tagtaatagt
     1681 tgccatacta actccaccaa tatatcttgt tatagcactt agttacctag ataagatatc
     1741 ctttagcttg cttccaaaat ttaagtctgc acctataata tgagttcata ttagtactgc
     1801 taaatcctat ctatagtaat gtcaaacacc taaataaagt catctctcca attcattcaa
     1861 gaaatgaaga aaggcaaaaa atctttaaaa taagaaaaat gcatattatc aggtgttcaa
     1921 aaatattgat gatatacgtt atatagatag aaagatttac tcaatctcat tttcaaattg
     1981 agttttttcc caacctcgtt tttaatttat atcttcaata aaatctaatg acctagttga
     2041 tatgttatat ggaataatat tatttaatct gtaatttttt taaaaaactt aatagtaaat
     2101 ttgctccact gattgctatc aatatttcaa ttggtaaaaa atagtaattc caaataaaat
     2161 gagaaatcag caatgataga aaaataacaa tatcaatttt cctgttgttg acatactctg
     2221 taattttatg atacaggaat gcaacaataa ctgaaattaa aacaatcaac ataatactat
     2281 tatcctatcc ttctcactaa ctctatttcc aaaatttaat ttttggggga cttagtaatg
     2341 aaattacaat taacaacaca cctaaaataa acaaaaatat ctcccaaact ttattctcag
     2401 ttttaataaa gctaccatat ctatctcatt tcttattttt aaataattca tactcttttt
     2461 ct
//
LOCUS       DAVHBD010000086         2357 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000086 DAVHBD010000000
VERSION     DAVHBD010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2357
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.086"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            532..636
                     /locus_tag="VVK04_002053"
                     /pseudo
     CDS             532..636
                     /locus_tag="VVK04_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_037603748.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            656..1231
                     /locus_tag="VVK04_002054"
     CDS             656..1231
                     /locus_tag="VVK04_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000497530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU3990656.1"
                     /translation="MFVGFLVYVIVATVGYTINQGDYFQNEHLFIIAKTFLISLSVAY
                     AKWFDMISLRRLTKKEVLLFIASFLLCVLVNIGYHSLFTVSSGAGYQHLEAASTGISL
                     SFIASATVFGPILEEFVFRGILQGAVFENSWLGLVLTASLFSFLHAPYDFPSFIYYLF
                     GGFMLGFAYKKSQKLSVAILVYICYNCLSFL"
     gene            1458..1646
                     /locus_tag="VVK04_002055"
     CDS             1458..1646
                     /locus_tag="VVK04_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990657.1"
                     /translation="MAALNTSLTTNIKFGLVGTVGGRFAGYGMYVLGYPGDYLDITNH
                     RVVSAKTSHKSYQILEND"
     gene            1676..2080
                     /locus_tag="VVK04_002056"
     CDS             1676..2080
                     /locus_tag="VVK04_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU3990658.1"
                     /translation="MKKIFATKRNVFLVRLLLGQIPLVVSTYLFLSRQFLNFSLVFQF
                     LLVIINLASILATVYLTREMRIRKFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     AESYQQIIAYIGAVLCLLIMLLLMWGLKYYKK"
BASE COUNT          734 a          348 c          460 g          815 t
ORIGIN      
        1 ggcctcaaac tctaaagtcc aaaaaggtag tcgtaaccta tatgcgtaaa tcacgagagt
       61 aaacgaggaa agatgtacga cttatcccgt gaggtctcat gagcgctaaa agcgtagtaa
      121 caacgaatca tgagaagtca gccgaaccca tagtagtgag gaaacttctg tagtggaagt
      181 ggagcgaagg ggtgaacaat tgaaagtaga attgtctgtt ttgattattt gtttgatagg
      241 atggtagtat gaaaatataa acggtgacta ttgttcataa aaaaaaggac acacgaatag
      301 aacgcttatg tagcctgaga gaggagttag ttaagaaatc tttgtaacaa ataaatatga
      361 ttgtgttaat cattattttg aaagcaaatg atatttctat tctgcagagc gaaaaatatc
      421 ataattggta cttttacaac taaatatatt cgctctgttg taaaatgaag tgcaacacaa
      481 aagacatgtt catctgatat actagagttg cgaaaaacag tataaaggaa gatgaacatg
      541 tccacaaact attctaccac aaatcaataa tacaatcact tatctgaagc tgaaagagga
      601 gaaattgaag cttatttaag cgtaggactt aaacctgttt aataaatatc atgccgtgtt
      661 tgttggattt ttagtctatg taatagtcgc tacagtaggc tataccatca atcaaggtga
      721 ttattttcaa aacgagcacc tatttattat tgcaaagact ttcttgattt cactgagtgt
      781 tgcctatgcg aaatggtttg atatgatttc gctaagaagg ttaacgaaaa aagaagttct
      841 actttttatt gcaagctttc ttctttgcgt gctggtaaat ataggttatc atagtctttt
      901 cacagtttct tctggtgcag gatatcaaca ccttgaggct gctagtacag gaatttcctt
      961 atcctttatt gcaagcgcga cagtttttgg ccctattctg gaggaatttg ttttcagagg
     1021 aatccttcaa ggtgcggttt ttgaaaattc ttggttgggg cttgtactga ctgcctctct
     1081 cttctctttc ctgcatgctc cttatgattt tccttcgttt atctattatc tatttggagg
     1141 tttcatgctg ggctttgctt ataaaaagag tcaaaaacta tcggtggcta ttttagttta
     1201 tatctgttat aactgtttat cattcctgta gtatatgtaa gtaatcaata tgacataaca
     1261 ttggacaaaa aatcttaaaa aatagggaaa tggatactat tactgtttag attaacaaca
     1321 ttaaatgaaa tgatgtcaca atttgagatt atggataccg aaatttttgc gaaagttgaa
     1381 ggaggtttag gaggttggga agaggtagct tttcaaaaaa ttatatggtt tggttggata
     1441 atcatgtgcg cattcttatg gcggctctta atacttctct cacaactaat atcaagtttg
     1501 gtctggttgg aacagttgga ggaagattcg ctggttatgg tatgtatgtt cttggttacc
     1561 caggtgatta tctagatatc accaatcata gagttgtttc tgctaaaaca tctcacaaaa
     1621 gttatcaaat tttagaaaat gattagatat catttaattg taatggagtt taggtatgaa
     1681 aaaaatattt gcaacaaaac gcaatgtttt cttagtgagg ttgttgttag gacagatacc
     1741 tttggttgtt tctacttatc tatttctatc tcgtcagttt ttaaattttt ccttggtttt
     1801 ccaatttctt ttagtgatta ttaacttggc ttctattttg gctactgttt atctcactag
     1861 ggaaatgagg ataagaaagt ttgaagatga tgatttggtt agtcctagaa ccaatcaact
     1921 catgtttatc ggcttgacag gttttatgtc tattatatgt ttgtatagag gtatcacagc
     1981 agcagaatcc tatcaacaaa taatcgctta tattggcgcg gttctctgct tgcttatcat
     2041 gcttttgctc atgtggggct tgaagtatta taaaaagtag agcttaatga agtataaaag
     2101 aaaagggtaa gtgtttttgc aatacttact cttttataat agattccctg cgaaacaaaa
     2161 tatggtatag tatagtatat tgaaactaga atagtacgcc tctacttcta aaacattgtt
     2221 agaaatcgat ttgactgtcc tgatcgattt atcctgttct tatttcattt tactatagtt
     2281 ctatgaatta tgaagcaagt aaacaactaa ccaatgcaca atttaagcgt cttgttggtg
     2341 ttcagcgcac gactttt
//
LOCUS       DAVHBD010000087         2174 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000087 DAVHBD010000000
VERSION     DAVHBD010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2174
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.087"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            231..962
                     /locus_tag="VVK04_002057"
     CDS             231..962
                     /locus_tag="VVK04_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990659.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHASYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            977..2128
                     /locus_tag="VVK04_002058"
     CDS             977..2128
                     /locus_tag="VVK04_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU3990660.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTLKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
BASE COUNT          794 a          276 c          403 g          701 t
ORIGIN      
        1 agttttatag tgaattgaat ctggaatatt acactacggt tcctaaaata ttttcagaaa
       61 gcgatttgaa tttcccaata aatttgttca gtttttaatt gattttacta tagaagatat
      121 aattttctaa attactctga cacagaactt taagaaaaag ctaattattg tagtaatttc
      181 tttaagaaaa tgatataatt cattaaaaag tatttggagg aggaagaatt atgttgaatc
      241 aggatctctt tgattcgctt gaggcacaaa aaattgtaga tactttgatg aaagggcaaa
      301 aagattatgt agatgaacgt ctagaaaaaa gagagacaat gatagtgtcg aatggttatg
      361 catggacgcg acctaatcat attgatactg catttgcatc agcagatttg tttgagtata
      421 aattacaatt agcaggacag acttggggat atttagaatt tgaaacaaac acagaaaaat
      481 atgggaaagt attgttaatt ataaaaggta agaagcgact tacgaaccaa tttcctttgg
      541 tacaaaaaaa taagagtggc tacttatttg aatatgctca aatgaataca ctttatctta
      601 atcaacatgc ttcctacaaa aatgatgaag atagtcattc ctttccaatt cagatggagt
      661 tagtttctga tgaaatgatt caagaaattg aacaagctac taaaaattcg aatatcgaaa
      721 aatttatgat tttaacttat gaggcggact cagaaaacaa tattatatct gtagatgttg
      781 ttatgcctga tgcacgaact ggtcagttac acttgattca agatttgtct gagtatattc
      841 aatcaagttc gtaccatttc gaagaagcta aatatcaaga tattcctaat ttttcagaat
      901 tatcggaaac agaagatttt gaaattattc caagaataga aaaacaagaa ggtcaaaagt
      961 agtaaggagt atgtaaatgt ttaatggtcg ggtattgaaa gaattacggc tgttaaatgg
     1021 tttaagtaga gcagaattag ctcagagaat taatttaacg gaacaagcca tttggcagtt
     1081 tgagtccaac gaaacgaaac ctaaattatc aaccaaaatg catttggcca accaatttca
     1141 tgttgattta acttattttg aacaggaaga agagagcatt cgatttgatt cttctgtaat
     1201 tgcctttaga aatgcagacc tagcaacacg gaaaacaata gatattcaaa ctatgtattt
     1261 acataaggta gatagtctga ttgattattt tgaaagtttt gtaattatac ctaatattac
     1321 aattcatgac ttaagtaatg tagtgagtga atcttatcat aagggagaat ccattgagga
     1381 attggctctt tatgccaggg aaaaattagg tatttcaaaa gataatcatg atttgcttta
     1441 taaattagaa cgttcaggca tctatatcgt ggaacgatta attaatggcc aagctgatgc
     1501 ttatagcgca tggtcaaaat tgggaagacc ttatattgtg ttgggaacga ataaatcatc
     1561 tgtacgtcga aattttgact tagctcatga gctaggacat attcttttac ataaatataa
     1621 agatatgaat gaagatggcg atcgtttgga gcaagaagca aattattttg catcatgttt
     1681 tttattgcca aaagaagagt ttttagtcaa atttgaagag agggttggca agcgtgtcag
     1741 caatcctgat agttatattt tattgaagtc ggatttgaat gtttcgatac aggctttaga
     1801 gtatcgagct tttaagttag gattattgac tctaaagcaa cattcttact tttatcgtca
     1861 aattgcgcaa aaaggttaca aaatgattga acctttggat gatcaaattt ttgttaaaaa
     1921 accaagcaaa gtaaagagta ttctggacgt cgttttgagt aatcatctag tcagtctagc
     1981 gactataatg tctaaacaaa gtattcgttt acagtttata agcgaaatat tttcagtcga
     2041 aatgaaattt tttgatcagt atcaagaaga tagaagaaca gatcgatttg ataacatcat
     2101 ccctttgtac aaaagaaata atttataatt taactgtgaa ataatttcat gaaggacata
     2161 tggcagaaat tgga
//
LOCUS       DAVHBD010000088         2151 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000088 DAVHBD010000000
VERSION     DAVHBD010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.088"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..1446)
                     /locus_tag="VVK04_002059"
     CDS             complement(<1..1446)
                     /locus_tag="VVK04_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU3990661.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPVSIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIREQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIK"
BASE COUNT          633 a          481 c          400 g          637 t
ORIGIN      
        1 cttaataacg ttgatatgat tgacctctgg atcttccgtc ccttggaggg agcaaccacg
       61 ttccttggcg aattggatat agtcgacaat ttctcgtgta atgcgttcac caggagccaa
      121 gataggaata cctggagggt aacacataac aaattctcca cagacctgtc caacagaatc
      181 atccaaagtt aaactttttc tttctgaata gaaggcttct tgcggagaca gcactaactc
      241 gggctgaata tattctcctg ctattaagtc cttcccatct cgtgaataga gtctcttaat
      301 atcagccaga gcaccaacca agcgctcgat gtcttggatg cggtcgccga tggaaatata
      361 ggccaagata ttgccgatat caccaaactc gatctgaatg tcgtattcgt ctcgcaagag
      421 gtcataaacc tcgatacctg ttaagccaat accctgagtg taaactgaca gcttagttac
      481 gtcaaaatcg caaaccgaaa caccgtctat tagctctttt gagtaggcat agtagccacc
      541 gatagcattg atttcacggc gggcatactc agatagctca atgactttct caaacgactc
      601 tttaccacga agggccaagt tgcgacgtga aatatccaaa ctagccatca acaagtaaga
      661 ggcagatgta gactgggtca ggtttataat ctgacgaacg tactcgggat tcatctgctc
      721 cctgattaaa agaagcgaac tttgtgtcaa actcccacca gacttatgca tggaaactgc
      781 tgccatatca gctcctgcat ccatagcaga aattggaagt ttatcagtga aatgcaaatg
      841 cgctccgtgg gcttcatcta ctaaaaccat catgccagct tcatgagcca tttctgtcaa
      901 cccctttagg tctgaacaga tgccgtagta agtaggattg ttgattagga tagccttagc
      961 atctggatgg tcctttatgg cctgtgctac tcggtcattt tcaagaccta aagcgatacc
     1021 aatcttagga tctacactca tctcgatata gatgggaatg gcaccacata gaaccaacgc
     1081 attgatagca gatttatgga catttcgtgg cagaataatc ttatctcctg ccttgcaggt
     1141 tgccagaatc atagtctgca ccgatgaagt tgttccacca atcattagaa aggcatggct
     1201 agctccaaaa gcatctgcag ccagctcctc tgcatcacga ataatcgaaa caggatggcc
     1261 taaattatcc aagggtttca tcgaattgac atcaatgcct acacattttt ctcctaagag
     1321 ttcgacaagt tctggatttc cccgtccacg cttgtgacct ggaacatcaa agggaacaat
     1381 ccttttcttg cgcaacttca ccaaggcctc ataaattggg gcttggtttt gatctaactc
     1441 tttcaaaaca tactcctttc aatattttta ggaccttatg aaaactaagg aactaaaggt
     1501 tgactcatga aaaaagagca ggttttcacc tgctctgcaa tcttctgacg tgtttatttt
     1561 ggtttctgtt gagtatgtct gttcccgatg tttcctaact ctctagtagc aaatattacg
     1621 tactttattg atcgtttcac aagatgacgt gtgctttcac cacactaaaa atttatgaat
     1681 taggacaagt gtcctaacat caacttataa aagtaggctt ttaaccctat caataatgtg
     1741 gcttttcaac cacgcttcgg cattcaaccc tgcctgtccg taggcatttt ttactcgggt
     1801 ttatatttgc tagaaaacat catctcattt tctaagcttt attactatat catgttttta
     1861 agaacttgta aagtattttt tgataaaaaa caaaaatata gtagattgaa actagaatag
     1921 tacacctctg cttctaaaac attgttagaa atagatttta ctgtcctgat cgatttgttc
     1981 tgttcttgtt tcattttact atatgttcgt aaatgaaagt tctataatga agttagccac
     2041 ccaaccctcc taaaaattag atggttcaac tagctgatag ctcttgtagg tataagaaaa
     2101 cacctctgtg ttatacttgt tgttcaacca caaacacaag aaaggcacag a
//
LOCUS       DAVHBD010000089         1995 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000089 DAVHBD010000000
VERSION     DAVHBD010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.089"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(1..274)
                     /locus_tag="VVK04_002060"
                     /pseudo
     CDS             complement(1..274)
                     /locus_tag="VVK04_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825319.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            609..>1995
                     /gene="pcpA"
                     /locus_tag="VVK04_002061"
     CDS             609..>1995
                     /gene="pcpA"
                     /locus_tag="VVK04_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU3990662.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT          726 a          286 c          317 g          666 t
ORIGIN      
        1 tgtttttaac acagctaaca tctcttcaaa agtggtgcgc tgaacaccaa caagacgctt
       61 aaatcgtgca tcggttagtt gtttacttgc ttcataattt cgcagggagt ctattgactc
      121 tttggtaggt gtcaatgttt ttttcatcta tcccgagaat tatttccccg ccatttgtat
      181 ttgcaaatgc tgagtaggtt tcccagaaag actctggaag attgttttta gcttttttgt
      241 attctaaatc aaccccttca aattttaagt ccatattttt cctttacatc tgttttttgt
      301 ggttctggta tttgttcaag ttgagtgata atatagcgaa ttgaatttcg agagttttta
      361 ctcagttaat ttctttttta acccacttta atttcttttt taacccgggt taaaaaagaa
      421 attaaagtgg gttaattttc cttgacttaa aatttaaaaa tgatatactg tgtttatgga
      481 gagatgacaa tttataaaat gtactactct attctactag ataatgattg aataaaactt
      541 tttataacaa cggctagcaa agttataatt ttatatctat tagaaaataa atatgtaagg
      601 aaatttaaat gaaaaaaact acaatattat cattaactac agctgcggtt attttagcag
      661 catatgtccc taatgaacca atcctagcag atactcctag ttcggaagta atcaaagaga
      721 ctaaagttgg aagtattatt caacaaaata atatcaaata taaggttcta actgtagaag
      781 gtaacatagg aactgttcaa gtgggtaatg gagttactcc tgtagagttt gaagctggtc
      841 aagatggaaa accattcacg attcctacaa aaatcacagt aggtgataaa gtatttaccg
      901 ttactgaagt agctagtcaa gcttttagtt attatccaga tgaaacaggt agaattgtct
      961 actatcctag ctctattact atcccatcaa gcataaaaaa aatacaaaaa aaaggcttcc
     1021 atggaagtaa agctaaaact attatttttg acaaaggcag tcagctggag aaaattgaag
     1081 atagagcttt tgatttttct gaattagaag agattgaatt gcctgcatct ctagaatata
     1141 ttggaacaag tgcattttct tttagtcaaa aattgaaaaa gctaaccttt tcctcaagtt
     1201 caaaattaga attaatatca catgaggctt ttgctaattt atcaaattta gagaaactaa
     1261 cattaccaaa atcggttaaa acattaggaa gtaatctatt tagactcact actagcttaa
     1321 aacatgttga tgttgaagaa ggaaatgaat cgtttgcctc agttgatggt gttttgtttt
     1381 caaaagataa aacccaatta atttattatc caagtcaaaa aaatgacgaa agttataaaa
     1441 cgcctaagga gacaaaagaa cttgcatcat attcgtttaa taaaaattct tacttgaaaa
     1501 aactcgaatt gaatgaaggt ttagaaaaaa tcggtacttt tgcatttgca gatgcgatta
     1561 aacttgaaga aattagctta ccaaatagtt tagaaactat tgaacgttta gccttttacg
     1621 gtaatttaga attaaaagaa cttatattac cagataatgt taaaaatttt ggtaaacacg
     1681 ttatgaacgg tttaccaaaa ttaaaaagtt taacaattgg taataatatc aactcattgc
     1741 cgtccttctt cctaagtggc gtcttagatt cattaaagga aattcatatt aagaataaaa
     1801 gtacagagtt ttctgtgaaa aaagatacat ttgcaattcc tgaaactgtt aagttctatg
     1861 taacatcaga acatataaaa gatgttctta aatcaaattt atctactagt aatgatatca
     1921 ttgttgaaaa agtagataat ataaaacaag aaactgatgt agctaaacct aaaaagaatt
     1981 ctaatcaggg agtag
//
LOCUS       DAVHBD010000090         1820 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000090 DAVHBD010000000
VERSION     DAVHBD010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1820
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.090"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            704..922
                     /locus_tag="VVK04_002062"
                     /pseudo
     CDS             704..922
                     /locus_tag="VVK04_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1222..1509)
                     /locus_tag="VVK04_002063"
                     /pseudo
     CDS             complement(1222..1509)
                     /locus_tag="VVK04_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1508..1771
                     /locus_tag="VVK04_002064"
                     /pseudo
     CDS             1508..1771
                     /locus_tag="VVK04_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          633 a          272 c          335 g          580 t
ORIGIN      
        1 gaacagaatc ctctcttgat tgaagacaag ctagtcatta ggctggtttg tctttttgtc
       61 aactgtagtg ggttgatata atagtattag tgagtgggat aaaagtttca tttagtttat
      121 tcagtacaaa tttaacgggt caagatttat atactggtgg tgtttttggg gctgagagaa
      181 gtatcttgat tttatgtgtg gtttttatac ttacagttgt tctgctccaa agagcttgta
      241 gagaagaatt agctcataaa ggagattgat tattttgata tcaaaaaaat gcacaggata
      301 acctgatgca tttttttagc gacaatgctt gctacttcct tctgtcgaat ttagacaatt
      361 ttaaataaaa gaatgaaata ttccctactg tatttttaga cgaagaacgt tagttaataa
      421 tactcaaatt tatttcaaac tctttgatta gtatgaattt agctctacag aaaaataaaa
      481 aatgtgataa aaatttcaac tactcttatc tataataaag ctacctgttc tttgaaaatt
      541 gaatccactc cgtcttgatt agcgtgcctg tgtaagtagg gactgagagt atttccctgt
      601 gaagggcaac tggcacaaga cgtgtgtgag aattttctaa cagacacgga gtttatcgtt
      661 tccagactca aacgatgcga caaactagat aaaggagtta atcatgaagg tagtaaactt
      721 gtatgatttg aaacaaatgg gaaataaagg tggttgtacc atccaattga ttcatcactt
      781 tccttttggt atgggcttag gacatctcaa aaaagactac attgaattta aacgtgttgg
      841 tatctttgat gggaaagcag tagaagttac tcttcgagaa ccttattcga gagatctact
      901 tcaggttgtc aagtcaataa agtaactgac accacgagta taattattag aaacgtggaa
      961 tcttattaaa ttttataata aatatattaa atgaaaaatt attagatata aacttatgta
     1021 ataaaacatt gaggaaataa taaaaatcta tgggtaatgt tctgaaagta cttttaggtt
     1081 aggagagaaa tataatgatt tttgaaaatt gattcaaaaa atagcgaatt gtagaaaacg
     1141 cttaacaaat ggtgtataat agacttccag cgaaacaaaa tatgctacaa taaacctatg
     1201 aattataaag taaccttata ctcatctgtc ttcacaaagc attctagtcc atctccgatt
     1261 aacgatggac tttatcatct ccttctccag tccttgtatg acatcttcca aagttcgaaa
     1321 ggctttattc ttaaatccac gtttacgaat ctctttccac acttattcaa tggggttcat
     1381 ttctggtgtg tatggaggaa taaatgcaaa gccaatatta gtcggaatct ttaaggcact
     1441 tgatttatgc catatagcat tgtccataac gaataaaaga taatcatctg gataagcttg
     1501 tgaaagcttg gctgacagtg gttatcaagg gctcatgaag atatatcttc aagcacaaac
     1561 tccacgtaaa tccagcaaac tcaagccgct aacagctgaa gataaagcct ataaccatgc
     1621 gctatctaag gagagaagca aggttgagaa tatttttgcc aaagtaaaaa cgtttaaaat
     1681 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc
     1741 tgatattatc aatcatgaac taggattcta gttttgcagg aagtctaata aatgtataag
     1801 aaaaaggagg aaaaaggatg
//
LOCUS       DAVHBD010000091         1716 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000091 DAVHBD010000000
VERSION     DAVHBD010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.091"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            506..1716
                     /gene="ltrA"
                     /locus_tag="VVK04_002065"
                     /pseudo
     CDS             506..1716
                     /gene="ltrA"
                     /locus_tag="VVK04_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT          580 a          294 c          392 g          450 t
ORIGIN      
        1 ggcttcaaac tctaaagtcc aaaaaggtag tcgtaaccta tatgcgtaaa tcacgagagt
       61 aattgaattc ggactaaggt ttgtgtgaaa agataaatct ttctagagtc taaagactct
      121 gcgtcagatt tcctattttc actgtaacct tttaacgtcc tcatatcttg tataaacgag
      181 gaaagatgta cgacttatcc cgtgaggtct catgagtgct gaaagcgtag taacaacgaa
      241 tcatgagaag tcagccgaac ccatagtagt gaggaaactt ccgtaatgga agtggagcga
      301 aggggtgaat actcaaacag tctggggaga gactgtttga ggtctgtcgc tagaaagaga
      361 aaacgacaga ttgaagtaat cctacttcac ttgtgtctgt aaaacgagag gtctgataga
      421 actggagtct gtcacgtatt gactagatga aggctcacca atataagatg tccctcaggc
      481 accaaaacaa gaaaggaata cgcacatgtc aaaattgcta gataagatat tatcacgcga
      541 aaatatgctg gaagcctaca atcaagtaaa atccaataaa ggctcagctg ggattgatgg
      601 aatgactatc gaagagatgg ataattatct cagacaaaac tggcgcttga ctaaggaact
      661 gataaaacag agaaaatata agcctcaacc agttcttaga gttgagatac ctaaaccaga
      721 cggaggtatc cgtcaactag gaattccaac agttatggat agaatgattc aacaggccat
      781 tgtctaagtc atgagcccca tttgtgaacc ccatttctca gatacgagtt atggtttcag
      841 accaaatagg tcatgtgaaa aagccatcat gaagctctta gaatacttaa atgacggcta
      901 tgagtggata gtggatatag acctagagaa atttttcgat acagttcctc aagatagatt
      961 gatgtcctta gtacataaca ttatcgaaga cggagatacg gaatccttga ttcgtaagta
     1021 tcttcattca ggtgttatca ttaatggtca acgttataaa acactagttg gtacaccaca
     1081 gggaggaaat ttatctcctc tcttatccaa tatcatgctt aatgaattgg acaaggaatt
     1141 agaaaagagg ggacttcgat ttgtgcgcta cgcagatgat tgtgtgatta cggtcgtaag
     1201 cgaggcagcc gctaagcgta tgatgtattc agtcagtcgt tttattgaaa aacggctagg
     1261 tttgaaagta aacatgacca agactaagat taccagacca agagagttga aatatctagg
     1321 ttttgggttc tggaaatcat cagatggttg gaaaagtcgt ccacatcaag atagtgttcg
     1381 gagatttaag cttaaattga agaaactaac acagaggaaa tggagtatag acctaacaag
     1441 acgtattgag caactgaatt tgtctattcg aggatggata aactatttct cattgggaaa
     1501 tatgaaaagt atagtcgcca gcatagatga gcgcttgcgt actcgcctac gagtgattat
     1561 ctggaagcaa tggaagaaga aatcgagacg attatgggga ttgcttaagt taggagttcc
     1621 taaatggata gcagataagg tatctggctg gggcgaccat tatcaattag tagctcagaa
     1681 gtcggtactt aaacgtgcta tatcaaaacc agtcct
//
LOCUS       DAVHBD010000092         1296 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000092 DAVHBD010000000
VERSION     DAVHBD010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1296
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.092"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            58..509
                     /locus_tag="VVK04_002066"
                     /pseudo
     CDS             58..509
                     /locus_tag="VVK04_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            674..973
                     /locus_tag="VVK04_002067"
     CDS             674..973
                     /locus_tag="VVK04_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU3990663.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          459 a          248 c          221 g          368 t
ORIGIN      
        1 ctatttttgg ttcattttac tataataata acgatactag ataatgagga aaatgcaatg
       61 gcaaacccaa ctttcggaga aaaaaagtga atacagacta tattgctcgc tatggcgtat
      121 atgcagttat ccctaatcct gaacaaaaac aaattgttct tgttcaagaa ccaaatggtg
      181 cttggttcct accatgtgga aaaattgaag caggtgaaaa tcatcaggaa gccctaaagc
      241 gtgagttgat tgaagagctt ggtttcacag cagaaattgg tacctattac ggacaagctg
      301 acgaatattt ctattctcgt catcgtgata cctactacta caatcctgcc tacctctatg
      361 aagcaactcc tttcaaagaa gtacaaaagc cactagaaaa ctttaatcat attgtctggt
      421 tccctattga cgaggctatc aaaaacctta aacgtggtag ccataaatgg gccattgaat
      481 cttggaaaaa acagcataag attggctaat actcttcgaa aataaaattc aaatcacgta
      541 agcgtcgcct taccgtactc aagtatagcc tgcggctagc ttcctagttt gctctttgat
      601 tttcattgag tataaatcaa gcgactctat tcaaaaagtg ttataataga attagaaaat
      661 cggaggaaat attatgaagc ttatcaatac gacaaactca cactcgcaac ttgtaaaaag
      721 tcaactagaa agtaccgatg caacccttgt tgaggtttat tctgcaggga atacagatgt
      781 tatttttacc caagctccgc ttcactatga aatcctcatc tcaaacaaac accgtgctat
      841 tcgtgagcct gaaatcgaaa ccattcaaga atttttcttg aaacgtaaaa ttgataagac
      901 ctctgttgat gaagccaata tcaagacact ctactcagag aaattaattg gaatttcaat
      961 cccaatcaag taagaaaatt gagtaaaaac tcgatttgag agaaagtcca ataagtcttt
     1021 ccataacaaa acgcatagta acaagagttt ctacacccac tattatgcgt ttttatcatt
     1081 ttgaaatcta ctgctaatca atgaagaagc aaagatcaaa ctaggcagct agttacaagt
     1141 tacgtaagcg cgtcataaca aggtatctat cctaattccc caacttccag tatactagat
     1201 aaaaaataat tatcggagga aaggtattgt actatgataa ttcaactaag tgatttaggt
     1261 caagttcacc ttgtttgtgg taagacagat atgagg
//
LOCUS       DAVHBD010000093         1228 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000093 DAVHBD010000000
VERSION     DAVHBD010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1228
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.093"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..199
                     /locus_tag="VVK04_002068"
     CDS             <1..199
                     /locus_tag="VVK04_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990664.1"
                     /translation="SKLKPLTVEDKTYNHALSKERSKVENIFAKVETFKMFSTTYRNH
                     RKRFGLRMNLIAGIINHELGF"
     gene            complement(937..1197)
                     /locus_tag="VVK04_002069"
     CDS             complement(937..1197)
                     /locus_tag="VVK04_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990665.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
BASE COUNT          412 a          231 c          205 g          380 t
ORIGIN      
        1 cagcaaactc aagccgctaa cagttgaaga taaaacctat aaccatgcgc tatctaagga
       61 gagaagcaag gttgagaaca tctttgccaa agtagaaacg tttaaaatgt tttcaacaac
      121 ctatcgaaat catcgtaaac gctttggatt acgaatgaat ttgattgctg gtattatcaa
      181 tcatgaacta ggattctagt tttgcaggaa gtctattata tatgcacaga catatgaaat
      241 ctttttgaga cagcagttat gatatattta tccattcaca acatcttctg tactaatact
      301 acaatattgg tacattttga ttacacaatc gtttcaaaaa atatgatgga agcctgagta
      361 ttttatagta attcccttcc tatcaactag atcaaccagt tgagtgttga atgttgaaac
      421 accctagcct cagcaaagga ctatgatcag catttcctag ccaataggac gctccaaatc
      481 acctattcta agttcatcac tagcttggtc agtaagatac agactgcaag gcaagactga
      541 cgtggttgat gagattttgg aagagtatta caatcataga ttcaccagta gacttgaccg
      601 cagatttaac tatagtagat tgaaactaga atagtacact tctgcttcta aaacattgtt
      661 agaaatcgat ttgactgtcc tgatcaattt gtcctgttct cgtttcattc tactatacta
      721 aaaaaccacc tgaaacaaat caagtgacta gaggataaaa acgaagactg ggcaaaaagt
      781 tttgaaaagc aaaaaacgca taatatcagg tcttgaaaaa ccttgatact atacgtttga
      841 ttgtgggaag attgacttca ttttctcctg aaattgaagt tttttctagt ttccagatat
      901 agacgaattc aatatagcca tctcgctaca attattttaa ccatcgagaa aatttttcag
      961 aatttcaaaa atttcatttt gatccaatga aatgtcatta ttttgaagaa tagttgactt
     1021 cacaggctct aattctatca caaagcggtg catgtctgct tttaccgcac tacttgatgt
     1081 tatagccgat aacttttcat ctcctagcaa ggaagctgtc aaacgggtaa ggtcattcaa
     1141 atgcttttta atggacttac ttaaaccttg agcacctgtg gcagagcgct ccctcatatc
     1201 cagccaagct ttagccttaa aaataatt
//
LOCUS       DAVHBD010000094          894 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000094 DAVHBD010000000
VERSION     DAVHBD010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.094"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..123)
                     /locus_tag="VVK04_002070"
     CDS             complement(<1..123)
                     /locus_tag="VVK04_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3990666.1"
                     /translation="MTIEPGQRIALVGQSGSGKSTLSKIPSGLYKIDTGKVLFYG"
     gene            536..832
                     /locus_tag="VVK04_002071"
                     /pseudo
     CDS             536..832
                     /locus_tag="VVK04_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813659.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          305 a          180 c          153 g          256 t
ORIGIN      
        1 accataaaat aaaacttttc ctgtatcaat cttatataat cctgatggta tttttgataa
       61 cgtacttttt cctgaccccg attgaccgac tagtgcaatt ctctgtcctg gctcaatagt
      121 caaatttaaa ttttctatta caggagctga gtctttggaa taagagaaag ataggtcctt
      181 aatatctatt ctacttcaaa cgtttctaaa ctatactccg gaaaataatt taaccaataa
      241 ctatctttca tcgtatcctc caaccagtac taagagtctg ggacaatagt ctcttatctc
      301 caaaaaaaag cggatttgcc gttgcttttt tgcatggttg cgatagtctt ggtaaaatag
      361 aattgcccaa taaaccattt agaaaggcta tcccatgcat attcactata acacaaatca
      421 aacaacttta ccactagaaa tcagttcttt cttgccgcaa gaccatctcg tctttactat
      481 tgaaaaagtg gtgaataccg atgaaaagga ggtaaaccat ctgattaaat atgccatgtt
      541 tgataaggaa caaaagagag gctataaaca gtcagctaga aacttagcga attagcacta
      601 taatgacaag gaggatagct atacacatcc tgatggctgg tattatcgtt ttcaccatac
      661 caaatatcag aaaacacaga cagactttca acaagaaatc aaggtttact acgccgacga
      721 acctgaatca gcccctcaaa agggactgta tatgaacgaa cgctatcaaa acttgaaagc
      781 taaagaagcc tttatctgcc caaagacaga ttttcgctca acgcaagatt gatgtggaac
      841 ctgtctttgg gcagataaag gcttctttgg gttacaagag atgtaatctg aggg
//
LOCUS       DAVHBD010000095          836 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000095 DAVHBD010000000
VERSION     DAVHBD010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.095"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(91..237)
                     /locus_tag="VVK04_002072"
     CDS             complement(91..237)
                     /locus_tag="VVK04_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990667.1"
                     /translation="MKTKEQTRKLASGCSKHCFEVVDRTDVVSNHTHGKATLTWFEEI
                     FEEY"
     gene            251..613
                     /locus_tag="VVK04_002073"
     CDS             251..613
                     /locus_tag="VVK04_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU3990668.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDVMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          263 a          127 c          160 g          286 t
ORIGIN      
        1 cacgtacggt ggtgtgagag gggctagaga ttatccccta ctcgatttcg aaatctagtg
       61 gaatgaatct ggaatagtcc atcgagcttt ctaatactct tcgaaaatct cttcaaacca
      121 cgtcaacgtc gccttgccgt gcgtatggtt actgactacg tcagttctat ccacaacctc
      181 aaaacagtgt tttgagcaac ctgaggctag tttcctagtc tgctctttgg ttttcattga
      241 gtataacaca ttgttagaag ttggtttaaa ttccctaatc agtttgttca catttacctt
      301 cgatatatta tatcccatag ttaaggttgg tcatacagat gattatagtc atggagccgt
      361 aaaacttagt gtttctttag ttgacaaaga tgtcatgaaa aaaatatctg taactgtaat
      421 aggatatttt gaaataaata tagatgaaaa tatcaccgat attctatacg taaatggtac
      481 tgctattctt tatccttatt tacgttctat tgtttcaata gtttcggcaa ttgatagcag
      541 tgaagcaatg ttgctaccta ccattaatgt tttagagtta ctagataaat ctcaaccttt
      601 tgaagaagaa taatttatta gctcactaaa ttgagggtaa ggaaaagtaa aatcagtaag
      661 aaaaatgtct tgcattatac agcaaccttt tgggaatgag tagatggatt gaataaaatt
      721 tgattaagag tggatgattt atctgtagat tattattgga cagttagtct tgaagtagtc
      781 taagaattag gttataatca gtagaagcct tgctaataat gaggaggtta gtttat
//
LOCUS       DAVHBD010000096          832 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000096 DAVHBD010000000
VERSION     DAVHBD010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.096"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>832
                     /locus_tag="VVK04_002074"
     CDS             <1..>832
                     /locus_tag="VVK04_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU3990669.1"
                     /translation="EEAKESRNEEKVKQAKAKVESKKAEATRLEKIKTDRKKAEEAKR
                     KAAEEDKVKEKPAEQPQPAPAPKPEKPAPAPKPEKPAPAPKPENPAEQPKAEKPADQQ
                     AEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWL
                     QNNGSWYYLNANGSMATGWLQYNGSWYYLNANGDMATGWLQNNGSWYYLNANGSMATG
                     WLQYNGSWYYLNANGDMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMA
                     T"
BASE COUNT          327 a          183 c          181 g          141 t
ORIGIN      
        1 gaggaagcta aggaatctcg aaacgaggaa aaagttaagc aagcaaaagc gaaagttgag
       61 agtaaaaaag ctgaggctac aaggttagaa aaaatcaaga cagatcgtaa aaaagcagaa
      121 gaagctaaac gaaaagcagc agaagaagat aaagttaaag aaaaaccagc tgaacaacca
      181 caaccagcgc cggctccaaa accagaaaaa ccagcgccgg ctccaaaacc agaaaaacca
      241 gctccagctc caaaaccaga gaatccagct gaacaaccaa aagcagaaaa accagctgat
      301 caacaagctg aagaagacta tgctcgtaga tcagaagaag aatataatcg cttgactcaa
      361 cagcaaccgc caaaaactga aaaaccagca caaccatcta ctccaaaaac aggctggaaa
      421 caagaaaacg gtatgtggta cttctacaat actgatggtt caatggcgac aggatggctc
      481 caaaacaatg gctcatggta ctatctaaac gctaatggtt caatggcaac aggatggctc
      541 caatacaatg gttcatggta ctacctaaac gctaatggtg atatggcgac aggatggctc
      601 caaaacaatg gttcatggta ctacctaaac gctaatggtt caatggcgac aggatggctc
      661 caatacaatg gctcatggta ctacctaaac gctaatggtg atatggcgac aggatggctc
      721 caaaacaatg gctcatggta ctacctaaac gctaatggtt caatggcgac aggatggctc
      781 caaaacaatg gctcatggta ctacctaaac gctaatggtt caatggcgac ag
//
LOCUS       DAVHBD010000097          817 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000097 DAVHBD010000000
VERSION     DAVHBD010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.097"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>817
                     /locus_tag="VVK04_002075"
     CDS             <1..>817
                     /locus_tag="VVK04_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU3990670.1"
                     /translation="EIAKQAEALSRTKNELSGVKSAQATYEETTTRRLSELTNLANGK
                     ASKSELTQTAEELSSKIASVQVGGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTID
                     VSDSPVTGFDKAIRLTSSNARDQIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYW
                     QVNDNSGISPIFTLKDENWTKLSFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLE
                     DGSLATSSKEAPEDIEGQISTVESTFKQRANSLEAGVNRLTEGLRTKVDISAL"
BASE COUNT          254 a          163 c          215 g          185 t
ORIGIN      
        1 ctgagattgc caagcaagct gaagcactta gccggactaa aaatgaactg tctggcgtga
       61 agtcagcgca agcgacgtat gaggagacga cgactcgtag actgtcagaa ctgaccaact
      121 tggccaatgg taaagccagc aagtcagaac tcacgcagac agctgaggag ctctctagta
      181 agatagcgag tgtgcaggtc gggggtagga attatatccg gggtacaaag cgcatgatgc
      241 tagccagagg attgtgggca tcaggtactt ttagaccgtc aggcgctggg acggcaaaga
      301 cgattgatgt atcagacagt ccagtaactg gctttgataa agcgatacga ttgacctcaa
      361 gcaatgctag agaccaaata ggtattgctc aagatggatt ttatatctcg caaggcacat
      421 acacgatgtc ttgttgggtc aaaggcagaa gaggtcaaaa ggtcaagcta caaacttatt
      481 ggcaagtcaa tgataattcg ggtatttcgc ccatctttac attaaaggat gaaaattgga
      541 caaagctatc gtttactagc gctagaaata gggctggagt cgcatcaatt ggctatgtgt
      601 atctcgtaaa tgctgaagtc ggagaatatt tagatgttct tgcgccccag ctggaagacg
      661 gaagtttggc aacaagctca aaagaagctc ctgaagatat agaaggtcag atttcaacag
      721 ttgaatcgac ctttaaacaa cgagccaact cgctcgaagc tggtgtgaat cgtctgactg
      781 aaggccttag aaccaaagtg gatatcagcg cactcaa
//
LOCUS       DAVHBD010000098          734 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000098 DAVHBD010000000
VERSION     DAVHBD010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.098"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>734
                     /locus_tag="VVK04_002076"
     CDS             <1..>734
                     /locus_tag="VVK04_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU3990671.1"
                     /translation="GSIRQEILNATKDKASKSELTQTAEELSSKIASVQASGRNLFLN
                     SLFKQDISKTGIWTTSTYTATIDSESKYLGHKALKIIGLNPSGRDGGNPKITYPALGQ
                     FGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPK
                     GWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFK
                     QRANSLDAGVRSLTEGLRTKVDISSL"
BASE COUNT          252 a          140 c          164 g          178 t
ORIGIN      
        1 ggctctatcc gtcaggaaat cctgaacgca accaaggata aagccagcaa gtcagaactt
       61 acgcagacag ctgaggagct ctctagtaag atagcgagtg tgcaggcatc cggtcgaaat
      121 ctattcttga actcactatt caagcaggat atttcaaaaa caggaatttg gacaacgagt
      181 acatatacgg ctactatcga tagcgaaagt aagtatcttg gacacaaggc tcttaaaatt
      241 ataggtctga atccatctgg ccgtgatgga gggaatccca agattactta tccagctctg
      301 ggtcaattcg ggaaagtaat tcccggaagt acgactaatc aagatgtaac cattagtttt
      361 tatgctaagg caaataaaaa tggaataatg ctaagatctc gattagggaa tatcggatat
      421 aaaactggaa atgtgacatt gtcgacagaa attaaacgat atgttgtcca tattccaaaa
      481 ggttggacaa acgaatccaa gcagaccaca aatgaatggt tgttcaattt caaccaggaa
      541 ggaaccgttt ggatttggat gccgaagttt gaaataagcg atgtagatac ttcttattca
      601 gaagctcctg aagatataga aggtcagatt tcaacagtag aatcgacctt caaacaacga
      661 gccaactcgc tcgacgctgg tgtgagaagc ttgactgaag ggcttagaac caaagtggat
      721 atcagctcac tcaa
//
LOCUS       DAVHBD010000099          702 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000099 DAVHBD010000000
VERSION     DAVHBD010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.099"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
BASE COUNT          259 a           69 c          132 g          242 t
ORIGIN      
        1 agttacttga cagttattat attttcgctc ataatataga taaaaggatg ggataggagt
       61 ttaaaaattt gaaagcgcta tccataatca taacgcataa ttttctcctt ttcgtgaaaa
      121 aagttaacgt aattttgaaa tgagcttaat aagaggtact atgtaggtag aaaataaaga
      181 taggagaaaa agtatgaata aaaaaatatt ttgtattcta gtatgtatta tatcattgat
      241 tagtctagct ataatctttc catggggctg gtcgatataa tgtaagggag cttgagttgt
      301 tagtggagga taaaatgtta agagtaatag tagttattca atctttagta ataatactgc
      361 ttgctgttgc tttattatta tctcggaaaa actttgattc gttaaatgtt gttcttataa
      421 tgatgatcgt atcacaattg ttgttattag tatatttgat aaaatcaggg aatcagtgat
      481 tagctgttat ttgaattaag taaactgtta agcttcaagc agtaactggt tttaaatatt
      541 taaaataaga taaaggaagg aagtctaatt taggtaacta aacaaagcct gcgatcactt
      601 gttaggaaac catcctaacc atgcttaata aaaaaggaga aaataaatgg aacttgtatt
      661 accaaataat tatgttgtga ttgatgaaga agagatgatg ta
//
LOCUS       DAVHBD010000100          696 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000100 DAVHBD010000000
VERSION     DAVHBD010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.100"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(330..641)
                     /locus_tag="VVK04_002077"
     CDS             complement(330..641)
                     /locus_tag="VVK04_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990672.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCSFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          231 a          130 c          107 g          228 t
ORIGIN      
        1 aaactcttac gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac
       61 tgagaacatc caccacggtt ggcatcacgc atactctaga cgcaattcta atcttttaga
      121 ctttgcataa taactgttaa acagttgaaa attaacccag ttttaacaag tagtcaaaat
      181 accagataaa ggaaaaaagt ctttaaaatc ttaaaaacgc atagtatcag gtattgaaca
      241 atcttgatat tatgcgtttt attgtgggaa gatttacttc attttctctt ggaattgagt
      301 tttctcctac ttcaaaacta gatgatttgc tatttaaaat agcgttcctt atgattttgg
      361 caacctggat taaagcgaga aaaacaaaag gagcaactta aactttcttt atattgctta
      421 tatgttagta gttttagaca aacaccacat aaaataggct tatcctgtat caaagataag
      481 ggatacggct caaaagggtg attttctaat gaatcatgac accgataaca agcatagtac
      541 tttttacaat catagcattg taaagcaata atatccaact tgctatggta atgaatgcat
      601 cttgtttgct tatccactaa gaaaccctgt gcctctatca tttccttttc ctttcttaag
      661 cacgaactgt gacgctggtt ccatcttcct tataaa
//
LOCUS       DAVHBD010000101          692 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000101 DAVHBD010000000
VERSION     DAVHBD010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.101"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(74..147)
                     /locus_tag="VVK04_002078"
     tRNA            complement(74..147)
                     /locus_tag="VVK04_002078"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VVK04_002079"
     tRNA            complement(157..242)
                     /locus_tag="VVK04_002079"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VVK04_002080"
     tRNA            complement(250..321)
                     /locus_tag="VVK04_002080"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VVK04_002081"
     tRNA            complement(344..416)
                     /locus_tag="VVK04_002081"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VVK04_002082"
     tRNA            complement(435..516)
                     /locus_tag="VVK04_002082"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VVK04_002083"
     tRNA            complement(522..594)
                     /locus_tag="VVK04_002083"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VVK04_002084"
     tRNA            complement(619..691)
                     /locus_tag="VVK04_002084"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVHBD010000102          678 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000102 DAVHBD010000000
VERSION     DAVHBD010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.102"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..623
                     /locus_tag="VVK04_002085"
     CDS             <1..623
                     /locus_tag="VVK04_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990673.1"
                     /translation="LLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCL
                     DIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAP
                     RSIGTTSPAREFEIIENIKHYKRLIDKAETCVNDLMAEFNSIITTVTGIGNRLGAVIL
                     AEIQNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMVKRGSPHLR"
BASE COUNT          201 a          152 c          134 g          191 t
ORIGIN      
        1 aacttctttc tgaccccaat cgtgaacaat ttcaacacga taatcggcaa gtagacctaa
       61 aaatactggc tagacatatt catcgtctca agaaaaaaca gtctgattgg aaagtacaat
      121 acactcgttg tcttgatatc atctttcctg agttggataa aatcgttgga aagcattcag
      181 aatataccta ccaactcttg acgcgctacc ctaatcctca gaaaaggatt gaggcaggat
      241 ttgataagct gatagaaatt aagcgattga ccgcttctaa aattcaggat atcctctcag
      301 tcgcacctcg ttctatcgga acaacatctc ctgctcgtga attcgaaatc atcgaaaaca
      361 tcaaacatta caagaggctc attgacaagg cggaaacatg tgtcaatgac ttgatggctg
      421 agttcaactc gatcatcacg acggttactg ggattgggaa tcgtttaggg gcggtcattt
      481 tagccgagat tcaaaatatt catgcctttg ataatcctgc tcaattacaa gctttcgctg
      541 gactggattc ttctatttat cagtcaggtc agattgattt agctggaaga atggtcaaac
      601 ggggttcccc tcatctgcgg taggtactca tacaagctgc caaagcatgc cctcgctttt
      661 cacctgcttt taaggcct
//
LOCUS       DAVHBD010000103          678 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000103 DAVHBD010000000
VERSION     DAVHBD010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.103"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..115
                     /locus_tag="VVK04_002086"
     CDS             <1..115
                     /locus_tag="VVK04_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU3990674.1"
                     /translation="TLEDVMNQLQDVIQGLEKEVIKSIVNRRWTRMLFESR"
     gene            complement(232..579)
                     /locus_tag="VVK04_002087"
     CDS             complement(232..579)
                     /locus_tag="VVK04_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU3990675.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
BASE COUNT          224 a          132 c          116 g          206 t
ORIGIN      
        1 aactttggaa gatgtcatga atcaactcca agatgtcata caaggactgg agaaggaggt
       61 gataaagtcc atcgttaatc ggagatggac tagaatgctt tttgaaagca gatgagtatt
      121 atatgcaatt tctttatata aaaagaccgg attgctccga tctttcaata gttcatattc
      181 tcaatttcta ttttaaaaat agctaaggtt aacgtcaaat gactacgcga cctatttcat
      241 acgataaaaa tcaagcacta gaccagcagg tccttgaact aataaggact ctgttcccca
      301 atcggttaca gttggtccgt gtaaaacctt tataccaagc tcgttcaacc gtttgtagtt
      361 ctggtctaca tcctcaacct cgatatgaat aatgattcct gactgaaagt tttccaaagg
      421 aaccaaatga ttttgtgaca acataaggca gtgactacca atcgtaaact gagcaaaacc
      481 atcatcagca taatctgcct ttttatccaa aatatgctcc aagtcagcac agacttgggg
      541 aacatttgaa acgataatat ctaattgatt taaattcatt tactctcctc cataaaaaga
      601 ccggattgct ccgatctttt aggctctata atatttgtag tgggtaaatc cactatagat
      661 attatggagc ctatttta
//
LOCUS       DAVHBD010000104          675 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000104 DAVHBD010000000
VERSION     DAVHBD010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.104"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>675
                     /locus_tag="VVK04_002088"
     CDS             <1..>675
                     /locus_tag="VVK04_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU3990676.1"
                     /translation="ESDGLVFDPAQITYRTANGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHP
                     ERLGKPN"
BASE COUNT          216 a          146 c          134 g          179 t
ORIGIN      
        1 gaatctgatg gcctagtatt tgatccggca caaataacat atcgtacagc caatggtgta
       61 gctgtccctc atggtaacca ttaccacttt atcccttatg aacaaatgtc tgaattggaa
      121 aaacgaattg ctcgtattat tccccttcgt tatcgttcaa accattgggt accagattca
      181 agaccagaac aaccaagtcc acaatcgact ccggaaccta gtccaagtct gcaacctgca
      241 ccaaatcctc aaccagctcc aagcaatcca attgatgaga aattggtcaa agaagctgtt
      301 cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta tatcccagcc
      361 aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa gcaggaaagt
      421 ttatctcata agctaggagc taagaaaact gacctcccat ctagtgatcg agaattttac
      481 aataaggctt atgacttact agcaagaatt caccaagatt tacttgataa taaaggtcga
      541 caagttgatt ttgaggcttt ggataacctg ttggaacgac tcaaggatgt ctcaagtgat
      601 aaagtcaagt tagtggatga tattcttgcc ttcttagctc cgattcgtca tccagaacgt
      661 ttaggaaaac caaat
//
LOCUS       DAVHBD010000105          662 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000105 DAVHBD010000000
VERSION     DAVHBD010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.105"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            264..626
                     /locus_tag="VVK04_002089"
     CDS             264..626
                     /locus_tag="VVK04_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990677.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHTFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
BASE COUNT          224 a           98 c          144 g          196 t
ORIGIN      
        1 aaaacaagaa caccttgctt ggcgcagggt gtttcgcgtg aaacagaaga attatctggt
       61 ttcaaatgct acagttagac aaacttatga taaaatagca gaaagtgaat gtttcctaag
      121 agcaattcta tcgatgagca attggaggta ttatgctaca cttaaaatta gtaaaacaag
      181 aaatagaagc tgaaaagcca gcatctgtag aagcttggat catttccgtc aaatttaaaa
      241 aaggttgcta ccgacatata tagattccaa aaacaaaaac gttagcggaa ctagcagatg
      301 tgattttatg gagttttgat tttgcaaatg atcatgctca cacatttttc atggataatg
      361 ttgagtggag tcatgcagat tcttactttc ttagctttgt tagtgacgat gttgaagaac
      421 gttacacaga aaatgtctat ctggatagcc taagtgtcaa acaaaaattt aagtttattt
      481 tcgacttcgg tgatgaatgg cgttttgaat gccaagtgct gagagaaatc gagacagagg
      541 acgaagaagc ttatctcgta cgttcggttg gaacgtcgcc agaacaatat ccagattatg
      601 atggttttga ctatgaagaa tggtaaaatt gaaatcagtc tgtgtgtagg cttagtattt
      661 ca
//
LOCUS       DAVHBD010000106          639 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000106 DAVHBD010000000
VERSION     DAVHBD010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.106"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>639
                     /locus_tag="VVK04_002090"
     CDS             <1..>639
                     /locus_tag="VVK04_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU3990678.1"
                     /translation="ESDGLVFDPAQITYRTANGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLGKPN"
BASE COUNT          214 a          122 c          124 g          179 t
ORIGIN      
        1 gaatctgatg gcctagtatt tgatccggca caaataacat atcgtacagc caatggtgtt
       61 gctgtaccgc acggagacca ttatcacttt attccttatt cacaactgtc acctttggaa
      121 gaaaaattgg ctcgtatgat tgctgttaag ggacaaaatg gtgcagtctt gccaggaatg
      181 cattatttga aaccagcacc aaaaccgcaa gttcaaccat caactgagaa aaaacaaact
      241 gattttgcag tagaacaggt tgttagaaaa gttggagaag gctatgttgt ggaaattgct
      301 ggtgtcagtc actatgtttt tgctaaagac ttggctaagg ataagattga tgctattgaa
      361 aatctcttgt ctaagaaaac tcaagagaca catgctctag ttgctaaaaa agaaaatgtc
      421 gctcctcgtg accaagaatt ttatgataaa gcttacaatc tgttaaccca ggctcataaa
      481 gtcttgtctg aaaataaagg tcgtacttct gatttccaag ccttagacaa attagcagaa
      541 cgcttgaata atgaatcttc taataaagta aaattggtag atgatttatt ggcattccta
      601 gcaccaatta cccacccaga acgccttggc aaaccaaat
//
LOCUS       DAVHBD010000107          592 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000107 DAVHBD010000000
VERSION     DAVHBD010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.107"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(9..488)
                     /locus_tag="VVK04_002091"
     CDS             complement(9..488)
                     /locus_tag="VVK04_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU3990679.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          159 a          140 c           80 g          213 t
ORIGIN      
        1 atgacttcct agtgggtacg gatagtaaac tccttaaaca caatgcgtaa gtctcttaat
       61 actctttgac gccctcgaaa tcgttcattg cttaagacgc gttctagttc ttcttgtttc
      121 tctttacttt gtttgtttct ataatctctt agtgtttcat gaaagagata ataatcatct
      181 agccagagac ccccctcact tatacgatga ctgatctctc ccacttcttc atagggttct
      241 ttatcgtatc tacgcttctg actttcctgc ttacggatat agtctaaaat tcgatttcga
      301 aacttggttt tgaaatattt ccttaaacgt ggaatatcgt ctaccagtcc ttcttctcta
      361 ctaatcaatt catgtaagca gagcatgcct tcttggtccc aatccgacaa ttcccataaa
      421 tgaaggtaat attcatttct acacttatac acagtccctt ggacttcttc atacaattct
      481 ttaatcataa ttttcccctt tctagataca gtctaacaga ttagaaaaca catttgttac
      541 attttctcca ttctgttccc tttagctcct aaactgcaca aaaaagagag gc
//
LOCUS       DAVHBD010000108          549 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000108 DAVHBD010000000
VERSION     DAVHBD010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.108"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>549
                     /locus_tag="VVK04_002092"
     CDS             <1..>549
                     /locus_tag="VVK04_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU3990680.1"
                     /translation="FSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCY
                     KAAVDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEY
                     KFVAEVVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRA
                     PNPMELLTIKVPQPVQSGDMVRA"
BASE COUNT          167 a          110 c          124 g          148 t
ORIGIN      
        1 ttttcaatgt cagccgttga catgtctatg attgaccaca ttccagatat gattgaaaat
       61 ggtgtggaca gtctaaaaat cgaaggacgt atgaagtcta ttcactacgt atcaacagta
      121 accaactgct acaaggcggc tgtggatgcc tatcttgaaa gtcctgaaaa gtttgaagct
      181 atcaaacaag acttggtgga cgagatgtgg aaggttgccc aacgtgaatt ggcaacaggt
      241 ttctactacg gtataccatc tgaaaatgag cagttgtttg gtgctcgccg taaaattcct
      301 gagtacaagt ttgtcgctga agtggtttct tatgatgatg cggcacaaac agcaaccatt
      361 cgtcaacgaa acgtcattaa cgaaggggac caagttgagt tttatggtcc aggtttccgt
      421 cattttgaaa cctatattga agatttgcat gatgccaaag gcaataaaat cgaccgcgct
      481 ccaaatccaa tggaactatt gactattaaa gtcccacaac ccgttcaatc aggagacatg
      541 gttcgtgca
//
LOCUS       DAVHBD010000109          504 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000109 DAVHBD010000000
VERSION     DAVHBD010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.109"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..163
                     /locus_tag="VVK04_002093"
     CDS             <1..163
                     /locus_tag="VVK04_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEU3990681.1"
                     /translation="HGNMYGVIKEVLKINEGLTIGSVRSPLTPVTEEDRPVVEEAAAL
                     IRETKERFL"
     gene            190..384
                     /locus_tag="VVK04_002094"
                     /pseudo
     CDS             190..384
                     /locus_tag="VVK04_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
BASE COUNT          167 a           91 c           98 g          148 t
ORIGIN      
        1 tcatggaaat atgtacggtg tcatcaaaga agttttgaaa atcaatgaag gcttgactat
       61 tggatctgtt cgttcaccat tgacaccagt gactgaagaa gatcgtccag ttgtagaaga
      121 agctgctgcc ttgattcgtg aaaccaagga gcgcttcctc taatccataa ggaggtattt
      181 atgacgcact acgttgccaa tccagaggtg gtcattctcg agggtggcat catgggacaa
      241 gaagctatcc tcaaaccaaa gattcgtgca gccttgaaag aagtcttggt tccaagtttg
      301 gctgagaaca caagattaga atttgctcat catcaaaaca ctgctggtat gcttggagcc
      361 tactatcatt ttaaaataaa ataaatttaa tatttacttt actaaattag tgtattcttc
      421 ctactttaat tagagaatga tttaagttct ctttaaaaat caaaagagtc taggacaaaa
      481 tagttctcaa tcacaaaaaa gcta
//
LOCUS       DAVHBD010000110          481 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000110 DAVHBD010000000
VERSION     DAVHBD010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.110"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..118
                     /locus_tag="VVK04_002095"
     CDS             <1..118
                     /locus_tag="VVK04_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU3990682.1"
                     /translation="LYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(204..>481)
                     /locus_tag="VVK04_002096"
     CDS             complement(204..>481)
                     /locus_tag="VVK04_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990683.1"
                     /translation="LLVMDNAIWQKSSILKIPTNIGFAFIPPYTPEMNPIEQVWKEIR
                     KCGFKNKAFRTLEDVMNQLQDVIQGLEKEVIKSIGNRRWNRMLFESR"
BASE COUNT          144 a           95 c           84 g          158 t
ORIGIN      
        1 cctttactgg gatggtcaag gattttggct actatataaa cgctttgaga acggaaaact
       61 gacttggcta agtacagaaa aggatgtcaa agctctcgca cctgaacaag tagattgact
      121 gatgaagggc ttttctatca ctccaaaaat aaatctatca gaaagtcgtg atttctattg
      181 aaatgaggac tttcttttta tactcatctg ctttcaaaaa gcattctatt ccatctccga
      241 ttaccgatgg actttatcac ctccttctcc agtccttgta tgacatcttg aagttgattc
      301 atgacatctt ccaaagttcg aaaggcttta ttcttaaatc cacatttacg aatctctttc
      361 cacacttgtt caatggggtt catctctggt gtgtatggag gaataaatgc aaagccaata
      421 ttagtcggaa tctttaagat acttgatttt tgccatatag cattgtccat aacgagtaaa
      481 a
//
LOCUS       DAVHBD010000111          438 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000111 DAVHBD010000000
VERSION     DAVHBD010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.111"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            30..>438
                     /locus_tag="VVK04_002097"
     CDS             30..>438
                     /locus_tag="VVK04_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990684.1"
                     /translation="MNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTDKKDAHGIALK
                     LLSDPNREQFQHDNRQVELKILARHIHRLKRKQSDWKIQYTRCLDIIFPELDKIVGKH
                     SEYTYQLLTRYPNPQKRLEAGFDKLIEIKRLTAS"
BASE COUNT          151 a           96 c           71 g          120 t
ORIGIN      
        1 aagatactgg acattatgcc tttaatctac tgaacttcct gcatgaacaa ggatataaag
       61 tttacaccta cactcctttg ctcatcaagg aatttgccaa atcattatca cttcgcaaga
      121 ctaaaacaga taagaaagac gctcatggca tcgctcttaa acttctttct gaccccaatc
      181 gtgaacaatt tcaacacgat aatcggcaag tagaactaaa aatactggct agacatattc
      241 atcgtctcaa gagaaaacag tctgattgga aaatacaata cactcgttgt cttgatatca
      301 tctttcctga gttggataaa atcgttggaa agcattcaga atatacctac caactcttga
      361 cacgctaccc taatcctcag aaaaggcttg aggcaggatt tgataagctg atagaaatta
      421 agcgattgac cgcttcta
//
LOCUS       DAVHBD010000112          429 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000112 DAVHBD010000000
VERSION     DAVHBD010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.112"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            76..>429
                     /locus_tag="VVK04_002098"
     CDS             76..>429
                     /locus_tag="VVK04_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEU3990685.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEEIAADLGIHESNLIRRSRWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEV"
BASE COUNT          140 a           80 c           91 g          118 t
ORIGIN      
        1 gtatcccagc aatgagcgtt ccagtatttg acaatattag acttcctgcg aaacaaaata
       61 tggtatagta gttccatgaa ttatgaagca agtaaacaac taactgatgc acgatttaag
      121 cgtcttgttg gtgttcaacg cacgactttt gaagagatat tagctgtatt aaaaacagct
      181 tatcaactta aacacgcaaa aggtggacga aaacctaaat taagcctaga agactttctt
      241 atggccactc ttcaatatgt gcgagaatat cgaacttatg aagaaattgc ggctgatctt
      301 ggtatccacg aaagcaactt aatccgtcgg agccgatggg ttgaagtaac tcttgttcaa
      361 agtggtgtta cgatttcaag aactcctctc agctctgagg acacggtaat gattgatgcg
      421 acggaagta
//
LOCUS       DAVHBD010000113          409 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000113 DAVHBD010000000
VERSION     DAVHBD010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.113"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..115
                     /locus_tag="VVK04_002099"
     CDS             <1..115
                     /locus_tag="VVK04_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU3990686.1"
                     /translation="ILEDVMNQLQDVIQGLEKEVIKSIVNRRWTRMLCENR"
     gene            complement(256..>409)
                     /locus_tag="VVK04_002100"
     CDS             complement(256..>409)
                     /locus_tag="VVK04_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU3990687.1"
                     /translation="LYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGF
                     SITPQI"
BASE COUNT          141 a           67 c           82 g          119 t
ORIGIN      
        1 aattttggaa gatgtcatga atcaactcca agatgttata caaggactgg agaaggaggt
       61 gataaagtcc atcgttaatc ggagatggac tagaatgctt tgtgaaaaca gatgagtata
      121 aaaagaaagt cctcatttca atagaaatca cgactttctg atgaatttat agtaaaatga
      181 aataagaaca ggacagtcaa atcgatttct aacaatgttt tagaagcaga ggtgtactat
      241 tctagtttca aaccactata tttggggagt gatagaaaag cccttcataa gccagtctac
      301 ttgttcagat gtgagagctt tgacatcctt ttctgtactt agccaagtca gttttccgtt
      361 ctcaaagcgt ttatatagta gccaaaatcc ttgaccatcc cagtaaagg
//
LOCUS       DAVHBD010000114          390 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000114 DAVHBD010000000
VERSION     DAVHBD010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.114"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(32..>390)
                     /locus_tag="VVK04_002101"
     CDS             complement(32..>390)
                     /locus_tag="VVK04_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU3990688.1"
                     /translation="EEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARA
                     LINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFVMKGG
                     KIVESGNHKYLMDLGG"
BASE COUNT          113 a           86 c           46 g          145 t
ORIGIN      
        1 ctcatttcct ttttgtatat aagctgtagt actatccacc aagatccatt aagtacttat
       61 gatttcctga ctcaacaatc ttaccacctt tcattacaaa aataatatcc gcatccttaa
      121 tcgttgacaa tctatgagct ataattattt gagtacaacc ctgactttgt atatactttg
      181 ttattctttc ctcattaata gtgtctaatg cactagttgc ttcatctaaa attacaatac
      241 taggattatt tattaatgca cgtgccagtg ctatccgttg cctttgccca cctgaaatat
      301 ttgaccccat ctctgagatg atagtattaa atttcatcgg catagccatg atttcatcat
      361 agatttgaac tgctttacaa acttcctcta
//
LOCUS       DAVHBD010000115          385 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000115 DAVHBD010000000
VERSION     DAVHBD010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.115"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(1..314)
                     /locus_tag="VVK04_002102"
                     /pseudo
     CDS             complement(1..314)
                     /locus_tag="VVK04_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          110 a           64 c           93 g          118 t
ORIGIN      
        1 agcccgaaaa atttctctgg ttccttattt tggaagtgaa acagcaagag ctgatagtgg
       61 tgtttcaagt cttgtgaata gctcaaaagc ttgtttaaaa tctctttatt ggttaagtgc
      121 atgcgaaaag tagggcgata aaaatgttta tcgctgagtt tacggctatc ctgttgaatg
      181 agtttccagt agcgcttgat agccttgtat tcatgggctt ttcgatgaaa ctgattcatg
      241 atttgaacac gcacacgact catagcacgg ctaagatgtt gtacaatgtg aaagcgttca
      301 agaacgattt tagcattcgg gagtgaaaca gtctgggaga ctgtttcagc ctgagcctag
      361 aaatttgaaa gcgaagctgt ttagc
//
LOCUS       DAVHBD010000116          363 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000116 DAVHBD010000000
VERSION     DAVHBD010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.116"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>363
                     /locus_tag="VVK04_002103"
     CDS             <1..>363
                     /locus_tag="VVK04_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU3990689.1"
                     /translation="EEAKPGNEEKIKKAKAKVESEKAEAIRLEEIKTDREEAKRKADA
                     KLKEAVENNAATSEQGEPKRRVKRGVLGEPATPDKKENDAKSSDSSVGEETLPSPSLK
                     PEKKVAEAEKKVAEAEKKA"
BASE COUNT          155 a           56 c           98 g           54 t
ORIGIN      
        1 gaggaagcta aacctggaaa cgaggaaaaa attaagaaag caaaagcgaa agttgagagt
       61 gaaaaagcag aggctataag gttagaagaa atcaagacag atcgtgaaga agctaaacga
      121 aaagcagatg ctaagttgaa ggaagctgtt gaaaacaatg cagcgacttc agagcaaggt
      181 gaaccaaaga ggcgggtaaa acgaggagtt cttggagagc cagcaacacc tgataaaaaa
      241 gaaaatgatg cgaagtcttc agattctagc gtaggtgaag aaactcttcc aagcccatcc
      301 ctgaaaccag aaaaaaaggt tgcagaagct gagaagaagg ttgcagaagc tgagaaaaaa
      361 gcc
//
LOCUS       DAVHBD010000117          345 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000117 DAVHBD010000000
VERSION     DAVHBD010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.117"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..>345)
                     /locus_tag="VVK04_002104"
     CDS             complement(<1..>345)
                     /locus_tag="VVK04_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU3990690.1"
                     /translation="GIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKRERYDG
                     LEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPKVDGPD
                     FELIKKLCDAGVD"
BASE COUNT           93 a           84 c           64 g          104 t
ORIGIN      
        1 atctacaccg gcatcacaga gtttcttaat caattcaaaa tctggaccgt ctacttttgg
       61 actgtaggat gtgtagcctg ataaggttgt tccgacaaag tcaattcctg cttctacagc
      121 tgctagccct tcttcgaaga tactagtatc agccatcaaa agctgattag gatatttctc
      181 cttaacctga cgaatgaact cttgaatttc caaaccatcg tagcgttcac gcttggtaca
      241 atccagagca atcacctcga tgtccagttc tgccaattca tcaacttctt tcatagtagc
      301 cgtgatgaag ggttcctgag gtggataatc acgtttgata atccc
//
LOCUS       DAVHBD010000118          343 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000118 DAVHBD010000000
VERSION     DAVHBD010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.118"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            1..343
                     /locus_tag="VVK04_002105"
                     /pseudo
     CDS             1..343
                     /locus_tag="VVK04_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811001.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          115 a           71 c           77 g           80 t
ORIGIN      
        1 agtcagctaa aaactgagcg aattggcact ataatgacaa ggaggatagc tacatacatc
       61 ctgatggctg gtgctatcgt tttcaccata tcaagcacca gaaaacacag acagactttc
      121 aacaggaaat caaggtttac tacgctgatg aacctgaatc agcccctcaa aaaggactgt
      181 atatgaacga acgctatcaa aacttgaaag ctaaagaatg tcaggcgctt ttatctcccc
      241 aaggtagaca gattttcgct caacgcaaga ttgatgtgaa acctgtcttt gggcagataa
      301 aggcttgttt gggtcacaag agatgtaatc tgaggggcaa gcg
//
LOCUS       DAVHBD010000119          340 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000119 DAVHBD010000000
VERSION     DAVHBD010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.119"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            1..340
                     /locus_tag="VVK04_002106"
                     /pseudo
     CDS             1..340
                     /locus_tag="VVK04_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT          110 a           63 c           76 g           91 t
ORIGIN      
        1 catttgaagg ctacagaggc agaagaattt gttacaattg atgccttatt tcaggcttat
       61 aaaaaggagt taggtcgttc ctacacacgt gatgccttct atcaactgtt gaagcgccat
      121 ggttggcgaa atattacgcc acgtccagaa catcctaaga aagcagacgc tcaaaccatt
      181 gtagtgtcta aaaataaaat ctcaattcaa gaagaaaaga aagcgattta aaaccagtag
      241 acgttttcgt aaggttcgct tgatgtacca agatgaggct ggtttcggta gaatcagtaa
      301 actgggatct tgttggtctc caataggagt aggtccacat
//
LOCUS       DAVHBD010000120          326 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000120 DAVHBD010000000
VERSION     DAVHBD010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.120"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
BASE COUNT          104 a           61 c           58 g          103 t
ORIGIN      
        1 atcgctctga acatcaaaaa agaaaggacg aaatttgtcc tttctcaagc ttagctgact
       61 tcaacccact acagttgaca aagagtcaaa aaaactccgt agtctctagc gctataaatc
      121 cggctagaga ttacagagtt atttttttat ctaaacttcc tacaagggta tattatctac
      181 tgaaaggata tggtatttgt agggaatact ttaaagagtt cttacaggaa gtcagtatta
      241 actagttata ttaggtttag tttacccatt caccattggc attgactcta tagctatcta
      301 cagttgtgtt gactgcaagg gcacct
//
LOCUS       DAVHBD010000121          316 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000121 DAVHBD010000000
VERSION     DAVHBD010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.121"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..280
                     /locus_tag="VVK04_002107"
     CDS             <1..280
                     /locus_tag="VVK04_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU3990691.1"
                     /translation="NVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLF
                     FIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEALYTYIAEATA"
BASE COUNT          107 a           60 c           53 g           96 t
ORIGIN      
        1 aaatgtagcg attcctcaca cagatattgt tcataatcta gctgaaaaag ttgtggtcgt
       61 tcgattagag aaaccggtga ctttccataa tatgattgcg ccagataagg aagtagaagt
      121 atccttgctc ttctttatca ttaataattc aagttcaagt caaacgaaca ttcttgctca
      181 gttaatggac ttcttcacag gaaatggtca tcttgaagac ctatcaaaaa tttctgaacc
      241 agaagccctt tatacttaca ttgctgaagc aaccgcttaa tcttgtctat taaaaaataa
      301 aatcggagga aatcca
//
LOCUS       DAVHBD010000122          315 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000122 DAVHBD010000000
VERSION     DAVHBD010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.122"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..279
                     /locus_tag="VVK04_002108"
     CDS             <1..279
                     /locus_tag="VVK04_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU3990692.1"
                     /translation="NVMIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGKEVEVSLLF
                     FIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIDEAIA"
BASE COUNT          108 a           53 c           57 g           97 t
ORIGIN      
        1 aatgtaatga ttcctcacac agatattgtt cataatctag ctgagaaagt ggtggttgtt
       61 cgattagaga aaccggtgac tttccataat atgattgcgc caggtaagga agtagaagta
      121 tccttgctct tctttatcat caataattca agttcaagtc aaacgaacat tcttgctcag
      181 ttgatggact ttttcacagg aaatggacat cttgaagacc tatcaaaaat ttccgaacca
      241 gaaaaacttt atgcttatat agatgaagca atcgcttaat cttgtctatt aaaaaataaa
      301 atcggaggaa gtcta
//
LOCUS       DAVHBD010000123          284 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000123 DAVHBD010000000
VERSION     DAVHBD010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.123"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>284
                     /locus_tag="VVK04_002109"
     CDS             <1..>284
                     /locus_tag="VVK04_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEU3990693.1"
                     /translation="TAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALS
                     PLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRANGTQTYSATVNVYG"
BASE COUNT           89 a           71 c           63 g           61 t
ORIGIN      
        1 acagcaggtg tcaaccatgt gattccatac gaactcttcg caggtgatgg catgttgact
       61 cgtctcttgc tcaaggcatc tgacaaggca ccatggtcag ataacggcga cgctaaaaac
      121 ccagccctat ctccactagg cgaaaacgtg aagaccaaag gtcaatactt ctatcaagta
      181 gccttggacg gaaatgtagc tggcaaagaa aaacaagcgc tcattgacca gttccgagca
      241 aatggtactc aaacttacag cgctacagtc aatgtctatg gtaa
//
LOCUS       DAVHBD010000124          283 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000124 DAVHBD010000000
VERSION     DAVHBD010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.124"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(1..283)
                     /locus_tag="VVK04_002110"
                     /pseudo
     CDS             complement(1..283)
                     /locus_tag="VVK04_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT           78 a           54 c           54 g           97 t
ORIGIN      
        1 ttaagtgatt taaatgtttt ctcatagcca taaaacattt ccgatttcag aatcccaaag
       61 aaggactcca tcataccgtt gtcttggctg tttcccttac cctctaagaa ccgatgataa
      121 gaatcgtgtt ggtattgcca gccttggtca ctatggagaa tcgtattctc gtagtgcttc
      181 tctgtgaatg cctgttccaa cattgtttgt acttattcta agttggatga agttgaaaga
      241 ttataggcga taatttcgat attaaagcca tctaaaactg gtg
//
LOCUS       DAVHBD010000125          277 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000125 DAVHBD010000000
VERSION     DAVHBD010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.125"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            1..277
                     /locus_tag="VVK04_002111"
                     /pseudo
     CDS             1..277
                     /locus_tag="VVK04_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           76 a           63 c           50 g           88 t
ORIGIN      
        1 ggtagaacac aagctgtcat ccgagatcac tttcttaaat atgatagagc cgtccgatgt
       61 cgcgtcaaaa tcattactat ggatatgttt agcccttact atgacttagc taaacagctt
      121 cgctttcaaa tttctaggct caggctgaaa cagtctccta gactgtttca ctcccgaatg
      181 ctaaaatcgt tcttgatcgc tttcatattg tacaacatct tagccgtgct atgagtcgtg
      241 tgcgtgttca aatcatgaat cagtttcatc gaaaatc
//
LOCUS       DAVHBD010000126          271 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000126 DAVHBD010000000
VERSION     DAVHBD010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.126"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>271
                     /locus_tag="VVK04_002112"
     CDS             <1..>271
                     /locus_tag="VVK04_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU3990694.1"
                     /translation="EIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIK
                     KDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRV"
BASE COUNT           89 a           57 c           67 g           58 t
ORIGIN      
        1 atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt tatatctttg
       61 atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat atgacccata
      121 gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc caggcttatg
      181 ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga aatactgagg
      241 caaaaggagc agaagctatc tacaaccgcg t
//
LOCUS       DAVHBD010000127          257 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000127 DAVHBD010000000
VERSION     DAVHBD010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.127"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>257
                     /locus_tag="VVK04_002113"
     CDS             <1..>257
                     /locus_tag="VVK04_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU3990695.1"
                     /translation="YHCSKMMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQ
                     LAISTSTVIRKLNDFHFECNFRNLPEIMSWDKYAFAKGKMS"
BASE COUNT           86 a           51 c           43 g           77 t
ORIGIN      
        1 tatcactgtt caaaaatgat ggtcgctgaa acttctatcg tcaagaaaaa tcaccaaatt
       61 cctcgtatta tcaaccaaaa gattgcgcaa aagttaattg aaaagatttc tatgaccgat
      121 attgcccatc agctggccat ttcaacttca actgtcattc gaaagctcaa tgacttccac
      181 tttgagtgta attttagaaa tctgcctgag attatgtctt gggacaaata tgcctttgca
      241 aaaggaaaga tgagctt
//
LOCUS       DAVHBD010000128          255 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000128 DAVHBD010000000
VERSION     DAVHBD010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..255
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.128"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..>255)
                     /locus_tag="VVK04_002114"
     CDS             complement(<1..>255)
                     /locus_tag="VVK04_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU3990696.1"
                     /translation="IVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQL
                     KDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIK"
BASE COUNT           74 a           54 c           40 g           87 t
ORIGIN      
        1 tttaatctct tcttttgtcc gaatattatc cgcatgagct gcatccttaa ggtaaacata
       61 gtatttaccg tttaccttaa tgacataacc acccttgatt tcattgacaa tgtctgaatc
      121 cttcaactga taattcggat ctttcatgag gagctcttca ctgatgatgg catcataagg
      181 aaccttgcca ttatagtaat gataatggtc tccatgagag gtcacataac cttgatccgt
      241 aatcttgata acaat
//
LOCUS       DAVHBD010000129          240 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000129 DAVHBD010000000
VERSION     DAVHBD010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..240
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.129"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            <1..>240
                     /locus_tag="VVK04_002115"
     CDS             <1..>240
                     /locus_tag="VVK04_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU3990697.1"
                     /translation="EKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPND
                     ESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          109 a           30 c           40 g           61 t
ORIGIN      
        1 tagaaaaagt agatgaatat gctgaaagtt ataatagact agaacagcta gataaagaat
       61 ttccagataa actaaaaaaa tctattcttc aatatgctat gcaaggaaaa ttagttgaac
      121 aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa aatacgagca gaaaaacaaa
      181 aactctttga agaaggcaag attaaaaaga aagatttgga catttctatt gtttcccaag
//
LOCUS       DAVHBD010000130          239 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000130 DAVHBD010000000
VERSION     DAVHBD010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..239
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.130"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
BASE COUNT           82 a           41 c           43 g           73 t
ORIGIN      
        1 aatgcttgta tctactcttc tatttgccta ttcacaaggg attttctctg gtcgaaaaat
       61 tgaaaaatgg aagagttagt gaccttagat tgtttgttta ttgacggaac taagattgaa
      121 gccaatgcca acaagtatag ttttgtgtgg aagaaaacga cagagaaatt ctccgccaaa
      181 cttcaagaac agatacaagt ctattttcaa gaagaaatca ctccccttct gattaaata
//
LOCUS       DAVHBD010000131          232 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000131 DAVHBD010000000
VERSION     DAVHBD010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.131"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
BASE COUNT           70 a           48 c           29 g           85 t
ORIGIN      
        1 cctttacatc gttttactat atcttacaat accttttaaa acagctatat tttgagcttt
       61 taaataaatg tttttacatc attttacaga gatttacgac acttttgccc cttttttgcc
      121 ccttttgagc aaacaaaaaa accgcaagcc tgagcctgcg gtgaaagaac aatttagaaa
      181 gtttcctttc tatttattta actgtaatca agccatctgg ctctactgtg aa
//
LOCUS       DAVHBD010000132          206 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate B4599
            SAMEA10254548-rid19607283.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAVHBD010000132 DAVHBD010000000
VERSION     DAVHBD010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA10254548
            Sequence Read Archive: ERR6890562
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001914932.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001914932.1
            Genome Coverage       :: 824x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/05/2023 17:17:59
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 40 of 110
            Pseudo Genes (incomplete)         :: 52 of 110
            Pseudo Genes (internal stop)      :: 36 of 110
            Pseudo Genes (multiple problems)  :: 14 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA10254548-rid19607283.denovo.132"
                     /isolate="B4599"
                     /isolation_source="Human, Blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="India"
                     /collection_date="1999"
     gene            complement(<1..>206)
                     /locus_tag="VVK04_002116"
     CDS             complement(<1..>206)
                     /locus_tag="VVK04_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU3990698.1"
                     /translation="IFLSFRAIINDTEYFLLIFLAFIYSIVSLPLYSVKNKIVSICLA
                     INSILLMSFPILINKFFPESFLTYT"
BASE COUNT           88 a           24 c           33 g           61 t
ORIGIN      
        1 gtataagtca aaaaactttc tgggaaaaac ttattgatta aaatggggaa actcattaac
       61 agaatcgaat ttatggctag acagatagat actattttat ttttcacaga atatagaggt
      121 agtgatacta ttgagtagat aaaagctaaa aaaataagca aaaaatactc cgtgtcattt
      181 ataatcgccc tgaatgataa aaatat
//
